Drug Side Effects

Most commonly reported drug classes:

Drug class Count
Nonsteroidal Anti-inflammatory Drug [EPC] 998995
Corticosteroid [EPC] 869535
Tumor Necrosis Factor Blocker [EPC] 779593
Platelet Aggregation Inhibitor [EPC] 581143
Benzodiazepine [EPC] 551647
Anti-epileptic Agent [EPC] 436944
Proton Pump Inhibitor [EPC] 430310
Kinase Inhibitor [EPC] 361453
Insulin Analog [EPC] 356098
Thalidomide Analog [EPC] 353495
Atypical Antipsychotic [EPC] 349878
Loop Diuretic [EPC] 337518
Factor Xa Inhibitor [EPC] 330564
HMG-CoA Reductase Inhibitor [EPC] 328378
Folate Analog Metabolic Inhibitor [EPC] 312342
Histamine-2 Receptor Antagonist [EPC] 290721
Provitamin D2 Compound [EPC] 262565
Angiotensin 2 Receptor Blocker [EPC] 246328
Progestin [EPC] 235323
Dihydropyridine Calcium Channel Blocker [EPC] 231431
Opioid Agonist [EPC] 231305
beta-Adrenergic Blocker [EPC] 230466
Retinoid [EPC] 215514
Integrin Receptor Antagonist [EPC] 204101
Nucleoside Metabolic Inhibitor [EPC] 202703
Vitamin C [EPC] 202113
Vitamin B12 [EPC] 202083
Interferon beta [EPC] 191749
Central Nervous System Stimulant [EPC] 190339
GLP-1 Receptor Agonist [EPC] 188226
Vitamin D [EPC] 188122
Calcium Channel Blocker [EPC] 187624
Thiazide Diuretic [EPC] 176650
Methylxanthine [EPC] 171001
Progestin-containing Intrauterine Device [EPC] 170907
CD20-directed Cytolytic Antibody [EPC] 166803
Mood Stabilizer [EPC] 166261
Alkylating Drug [EPC] 165914
Platinum-based Drug [EPC] 163999
RANK Ligand Inhibitor [EPC] 160234
Osmotic Laxative [EPC] 159979
Endothelin Receptor Antagonist [EPC] 152352
Estrogen [EPC] 151809
Expectorant [EPC] 137874
Vascular Endothelial Growth Factor Inhibitor [EPC] 130862
Xanthine Oxidase Inhibitor [EPC] 126897
l-Thyroxine [EPC] 126229
Sulfonylurea [EPC] 125430
Interleukin-17A Antagonist [EPC] 124516
Programmed Death Receptor-1 Blocking Antibody [EPC] 114888
Phosphate Binder [EPC] 114137
Calcium [EPC] 111842
Angiotensin Converting Enzyme Inhibitor [EPC] 110945
Azole Antifungal [EPC] 108011
alpha-Adrenergic Blocker [EPC] 108005
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 106233
PCSK9 Inhibitor [EPC] 105597
Parathyroid Hormone Analog [EPC] 104397
Aldosterone Antagonist [EPC] 103640
Microtubule Inhibitor [EPC] 103416
Leukocyte Growth Factor [EPC] 102754
Quinolone Antimicrobial [EPC] 97615
Interleukin-4 Receptor alpha Antagonist [EPC] 97452
Phosphodiesterase 5 Inhibitor [EPC] 96246
Selective T Cell Costimulation Modulator [EPC] 93108
Nucleoside Analog Antiviral [EPC] 90791
Prostacycline Vasodilator [EPC] 90388
Aminosalicylate [EPC] 88343
Proteasome Inhibitor [EPC] 79747
Interleukin-6 Receptor Antagonist [EPC] 79232
Antirheumatic Agent [EPC] 79059
Serotonin-3 Receptor Antagonist [EPC] 78518
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 77098
Aromatase Inhibitor [EPC] 76535
Calcineurin Inhibitor Immunosuppressant [EPC] 75615
Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 75492
Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 75206
Partial Opioid Agonist [EPC] 75151
Interleukin-23 Antagonist [EPC] 75099
Prostaglandin Analog [EPC] 73423
Nitrate Vasodilator [EPC] 72738
Erythropoiesis-stimulating Agent [EPC] 71636
Dihydrofolate Reductase Inhibitor Antibacterial [EPC] 68606
Antiarrhythmic [EPC] 67752
gamma-Aminobutyric Acid-ergic Agonist [EPC] 67478
Potassium Channel Blocker [EPC] 65366
Acetylcholine Release Inhibitor [EPC] 65075
Interleukin-12 Antagonist [EPC] 65036
Neuromuscular Blocker [EPC] 64891
Purine Antimetabolite [EPC] 64415
Peroxisome Proliferator Receptor alpha Agonist [EPC] 63706
Cardiac Glycoside [EPC] 63624
Dietary Cholesterol Absorption Inhibitor [EPC] 61899
Potassium Salt [EPC] 60660
Sulfonamide Antimicrobial [EPC] 60372
Androgen Receptor Inhibitor [EPC] 58967
Interferon alpha [EPC] 56575
Amide Local Anesthetic [EPC] 56338
mTOR Inhibitor Immunosuppressant [EPC] 55635
5-alpha Reductase Inhibitor [EPC] 54968
Macrolide Antimicrobial [EPC] 52570
Cytochrome P450 3A Inhibitor [EPC] 52273
Cholinergic Nicotinic Agonist [EPC] 52230
Nitroimidazole Antimicrobial [EPC] 49888
Catecholamine [EPC] 49237
Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor [EPC] 49147
Anti-IgE [EPC] 48739
HER2/neu Receptor Antagonist [EPC] 48615
Topoisomerase Inhibitor [EPC] 47475
Complement Inhibitor [EPC] 45095
Aromatic Amino Acid [EPC] 44418
Central alpha-2 Adrenergic Agonist [EPC] 44407
Nicotinic Acid [EPC] 44247
Insulin [EPC] 44217
Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 44211
Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 44132
Janus Kinase Inhibitor [EPC] 43896
Hepatitis C Virus NS5A Inhibitor [EPC] 43367
alpha-Adrenergic Agonist [EPC] 43349
beta-Adrenergic Agonist [EPC] 43348
Glycopeptide Antibacterial [EPC] 43122
Tetracycline-class Drug [EPC] 42456
Aromatic Amino Acid Decarboxylation Inhibitor [EPC] 39451
Protease Inhibitor [EPC] 39066
Androgen [EPC] 38684
Pyrimidine Synthesis Inhibitor [EPC] 36214
Epidermal Growth Factor Receptor Antagonist [EPC] 35830
Serotonin-1b and Serotonin-1d Receptor Agonist [EPC] 34312
Muscle Relaxant [EPC] 33123
Histamine-1 Receptor Antagonist [EPC] 31919
Polyene Antifungal [EPC] 31169
Cholinergic Muscarinic Antagonist [EPC] 30814
Copper-containing Intrauterine Device [EPC] 30613
Aminoglycoside Antibacterial [EPC] 30425
Sodium-Glucose Cotransporter 2 Inhibitor [EPC] 30115
General Anesthetic [EPC] 30093
Thiazide-like Diuretic [EPC] 29882
Pyridone [EPC] 29110
CTLA-4-directed Blocking Antibody [EPC] 28849
Sympathomimetic-like Agent [EPC] 26897
beta3-Adrenergic Agonist [EPC] 25117
Iron Chelator [EPC] 25070
BCL-2 Inhibitor [EPC] 25061
Intestinal Lipase Inhibitor [EPC] 24500
P2Y12 Platelet Inhibitor [EPC] 23563
Arteriolar Vasodilator [EPC] 22879
Interleukin-5 Antagonist [EPC] 22663
Lincosamide Antibacterial [EPC] 22302
Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 21387
Soluble Guanylate Cyclase Stimulator [EPC] 21130
CD38-directed Cytolytic Antibody [EPC] 20595
Alkaloid [EPC] 19828
Phenothiazine [EPC] 19751
Rifamycin Antibacterial [EPC] 19394
Estrogen Receptor Antagonist [EPC] 19369
Nitrofuran Antibacterial [EPC] 18682
Oxazolidinone Antibacterial [EPC] 18600
Vitamin D3 Analog [EPC] 18408
Typical Antipsychotic [EPC] 18144
Guanylate Cyclase-C Agonist [EPC] 17709
Aluminum Complex [EPC] 17564
Prostacyclin Receptor Agonist [EPC] 16736
Radiographic Contrast Agent [EPC] 16487
Anti-anginal [EPC] 16449
Potassium-sparing Diuretic [EPC] 16008
CD52-directed Cytolytic Antibody [EPC] 15888
Recombinant Human Deoxyribonuclease 1 [EPC] 15754
B Lymphocyte Stimulator-specific Inhibitor [EPC] 15658
Vitamin D2 Analog [EPC] 14811
Leukotriene Receptor Antagonist [EPC] 14759
Carbonic Anhydrase Inhibitor [EPC] 14734
Non-Standardized Food Allergenic Extract [EPC] 14705
Antimetabolite [EPC] 14545
Prostaglandin E1 Analog [EPC] 14491
Antimycobacterial [EPC] 14169
Hepatitis C Virus NS3/4A Protease Inhibitor [EPC] 14169
Progesterone [EPC] 14117
Cholinesterase Inhibitor [EPC] 13901
Dipeptidyl Peptidase 4 Inhibitor [EPC] 13809
Substance P/Neurokinin-1 Receptor Antagonist [EPC] 13770
Non-narcotic Antitussive [EPC] 13652
Potassium Binder [EPC] 13494
Cystic Fibrosis Transmembrane Conductance Regulator Potentiator [EPC] 13245
Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor [EPC] 13238
Macrolide [EPC] 13235
Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 13001
Anticholinergic [EPC] 12381
Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] 12168
Bile Acid [EPC] 12109
Thrombopoietin Receptor Agonist [EPC] 11709
Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC] 11631
Lipid-based Polyene Antifungal [EPC] 11543
Phosphodiesterase 4 Inhibitor [EPC] 11319
Orexin Receptor Antagonist [EPC] 11209
Standardized Chemical Allergen [EPC] 11188
Recombinant Human Growth Hormone [EPC] 11140
Influenza A M2 Protein Inhibitor [EPC] 10872
Barbiturate [EPC] 10790
Interleukin-1 Receptor Antagonist [EPC] 10703
Catechol-O-Methyltransferase Inhibitor [EPC] 10354
Melatonin Receptor Agonist [EPC] 10266
Lipopeptide Antibacterial [EPC] 10212
Parathyroid Hormone-Related Peptide Analog [EPC] 10002
Lymphocyte Function-Associated Antigen-1 Antagonist [EPC] 9783
Stimulant Laxative [EPC] 9670
Prostacycline [EPC] 9421
Asparagine-specific Enzyme [EPC] 9147
Non-Standardized Plant Allergenic Extract [EPC] 9091
Parenteral Iron Replacement [EPC] 8979
Antimetabolite Immunosuppressant [EPC] 8676
Glinide [EPC] 8324
Non-Standardized Chemical Allergen [EPC] 8256
Antidote [EPC] 8057
Programmed Death Ligand-1 Blocker [EPC] 7939
SARS-CoV-2 Nucleotide Analog RNA Polymerase Inhibitor [EPC] 7936
Bile Acid Sequestrant [EPC] 7891
RNA Synthetase Inhibitor Antibacterial [EPC] 7852
Antiprotozoal [EPC] 7821
Interleukin-2 Receptor Blocking Antibody [EPC] 7784
Vasopressin V2 Receptor Antagonist [EPC] 7766
Chloride Channel Activator [EPC] 7369
GLP-2 Analog [EPC] 7115
Hedgehog Pathway Inhibitor [EPC] 7102
Cannabinoid [EPC] 7078
Sulfone [EPC] 7058
Interleukin-5 Receptor alpha-directed Cytolytic Antibody [EPC] 6800
Peroxisome Proliferator Receptor gamma Agonist [EPC] 6530
Thiazolidinedione [EPC] 6530
Hydrolytic Lysosomal Neutral Glycosphingolipid-specific Enzyme [EPC] 6505
Vitamin K [EPC] 6214
Warfarin Reversal Agent [EPC] 6214
Antifibrinolytic Agent [EPC] 6192
Immunoglobulin G [EPC] 6114
Cephalosporin Antibacterial [EPC] 6101
Antimalarial [EPC] 5898
Antisense Oligonucleotide [EPC] 5855
CD30-directed Immunoconjugate [EPC] 5691
Adenosine Receptor Agonist [EPC] 5609
Farnesoid X Receptor Agonist [EPC] 5468
Hydrolytic Lysosomal Glucocerebroside-specific Enzyme [EPC] 5451
Antidote for Acetaminophen Overdose [EPC] 5378
Mucolytic [EPC] 5378
Thyroid Hormone Synthesis Inhibitor [EPC] 5369
Anti-coagulant [EPC] 5302
Vitamin A [EPC] 4936
Phosphodiesterase 3 Inhibitor [EPC] 4764
Survival Motor Neuron-2-directed RNA Interaction [EPC] 4763
Dopamine-2 Receptor Antagonist [EPC] 4762
Tissue-nonspecific Alkaline Phosphatase [EPC] 4759
Echinocandin Antifungal [EPC] 4755
Standardized Insect Venom Allergenic Extract [EPC] 4566
Prostaglandin E1 Agonist [EPC] 4374
Pediculicide [EPC] 4251
Tetracycline-class Antibacterial [EPC] 4248
Bismuth [EPC] 4219
Vascular Endothelial Growth Factor Receptor 2 Antagonist [EPC] 4201
Parathyroid Hormone [EPC] 4175
Paramagnetic Contrast Agent [EPC] 4157
Antiparasitic [EPC] 4135
Noncompetitive AMPA Glutamate Receptor Antagonist [EPC] 4108
SLAMF7-directed Immunostimulatory Antibody [EPC] 4099
Contrast Agent for Ultrasound Imaging [EPC] 4097
Non-Standardized Insect Allergenic Extract [EPC] 3849
Phenylalanine Metabolizing Enzyme [EPC] 3802
Somatostatin Analog [EPC] 3715
beta Lactamase Inhibitor [EPC] 3607
Vitamin D Analog [EPC] 3587
Osmotic Diuretic [EPC] 3559
Ergot Derivative [EPC] 3502
alpha-Glucosidase Inhibitor [EPC] 3496
Human Immunoglobulin G [EPC] 3485
Gadolinium-based Contrast Agent [EPC] 3474
Direct Thrombin Inhibitor [EPC] 3466
Progestin Antagonist [EPC] 3269
Antiseptic [EPC] 3085
Blood Viscosity Reducer [EPC] 2910
CD33-directed Immunoconjugate [EPC] 2895
Sulfonamide Antibacterial [EPC] 2804
Calcitonin [EPC] 2771
Selective T Cell Costimulation Blocker [EPC] 2761
Plasma Kallikrein Inhibitor [EPC] 2694
Sigma-1 Agonist [EPC] 2584
Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC] 2584
Neuraminidase Inhibitor [EPC] 2574
Antihypoglycemic Agent [EPC] 2527
Gastrointestinal Motility Inhibitor [EPC] 2526
Estrogen Agonist/Antagonist [EPC] 2519
Histone Deacetylase Inhibitor [EPC] 2488
Monoamine Oxidase Inhibitor [EPC] 2477
mu-Opioid Receptor Agonist [EPC] 2455
Monoamine Oxidase Type B Inhibitor [EPC] 2408
Recombinant Human Nerve Growth Factor [EPC] 2278
Cholinergic Receptor Agonist [EPC] 2192
Partial Cholinergic Nicotinic Agonist [EPC] 2192
Rifamycin Antimycobacterial [EPC] 2138
Actinomycin [EPC] 2124
Human Platelet-derived Growth Factor [EPC] 2106
Anthelmintic [EPC] 2090
Oxytocic [EPC] 2034
Skin Test Antigen [EPC] 1964
Tuberculosis Skin Test [EPC] 1964
Carnitine Analog [EPC] 1947
Monobactam Antibacterial [EPC] 1934
Vasodilator [EPC] 1919
CCR5 Co-receptor Antagonist [EPC] 1906
Calculi Dissolution Agent [EPC] 1836
Serotonin and Norepinephrine Reuptake Inhibitor [EPC] 1822
Cytolytic Agent [EPC] 1756
Hydrolytic Lysosomal Glycogen-specific Enzyme [EPC] 1685
Reducing and Complexing Thiol [EPC] 1680
Benzothiazole [EPC] 1668
Calcitonin Gene-related Peptide Receptor Antagonist [EPC] 1644
Lipid Emulsion [EPC] 1606
CD22-directed Immunoconjugate [EPC] 1602
Melanin Synthesis Inhibitor [EPC] 1598
Glucosylceramide Synthase Inhibitor [EPC] 1581
Macrolide Antibacterial [EPC] 1540
Uric Acid-specific Enzyme [EPC] 1538
Endoglycosidase [EPC] 1467
Photoenhancer [EPC] 1451
Live Attenuated Bacillus Calmette-Guerin Immunotherapy [EPC] 1344
Live Attenuated Bacillus Calmette-Guerin Vaccine [EPC] 1344
Insulin-like Growth Factor-1 Receptor Inhibitor [EPC] 1337
Penem Antibacterial [EPC] 1288
Pyrethroid [EPC] 1288
Interferon gamma [EPC] 1272
Humanized Monoclonal Antibody Fragment [EPC] 1234
gamma-Aminobutyric Acid A Receptor Agonist [EPC] 1207
Adrenocorticotropic Hormone [EPC] 1172
Non-Standardized Fungal Allergenic Extract [EPC] 1158
Calcitonin Gene-related Peptide Antagonist [EPC] 1150
Gonadotropin [EPC] 1148
alpha-Hydroxy Acid [EPC] 1140
Radioactive Diagnostic Agent [EPC] 1104
Hematopoietic Stem Cell Mobilizer [EPC] 1092
Cytomegalovirus DNA Terminase Complex Inhibitor [EPC] 1084
Gonadotropin Releasing Hormone Receptor Antagonist [EPC] 943
Surfactant [EPC] 943
Dihydrofolate Reductase Inhibitor Antimalarial [EPC] 932
Lymphocyte Growth Factor [EPC] 854
Interleukin-17 Receptor A Antagonist [EPC] 811
Leptin Analog [EPC] 799
Vesicular Monoamine Transporter 2 Inhibitor [EPC] 779
Polymyxin-class Antibacterial [EPC] 778
4-Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor [EPC] 755
Methylating Agent [EPC] 755
Amino Acid [EPC] 751
Oxaborole Antifungal [EPC] 733
Lipoglycopeptide Antibacterial [EPC] 729
Nucleoside Analog Antifungal [EPC] 726
Aldehyde Dehydrogenase Inhibitor [EPC] 718
Pleuromutilin Antibacterial [EPC] 711
Thyroid Stimulating Hormone [EPC] 706
Chemokine Receptor Type 4 Interaction [EPC] 697
Monoclonal Antibody [EPC] 697
Anthracycline Topoisomerase Inhibitor [EPC] 689
Opioid Antagonist [EPC] 586
Benzodiazepine Antagonist [EPC] 560
Glycolipid Disialoganglioside-directed Antibody [EPC] 539
Adenosine Triphosphate-Citrate Lyase Inhibitor [EPC] 534
Photoactivated Radical Generator [EPC] 530
Psoralen [EPC] 530
5-Lipoxygenase Inhibitor [EPC] 507
Standardized Animal Hair Allergenic Extract [EPC] 504
Adrenal Steroid Synthesis Inhibitor [EPC] 497
Plasma Volume Expander [EPC] 457
Hydrolytic Lysosomal Cholesteryl Ester-specific Enzyme [EPC] 455
Hydrolytic Lysosomal Triacylglycerol-specific Enzyme [EPC] 455
Non-Standardized House Dust Allergenic Extract [EPC] 435
Ester Local Anesthetic [EPC] 424
Carbamoyl Phosphate Synthetase 1 Activator [EPC] 418
Tricyclic Antidepressant [EPC] 381
Mucocutaneous Epithelial Cell Growth Factor [EPC] 368
Non-Standardized Pollen Allergenic Extract [EPC] 364
Standardized Pollen Allergenic Extract [EPC] 364
Sclerosing Agent [EPC] 316
Interleukin-6 Antagonist [EPC] 271
CD4-directed Blocking Antibody [EPC] 245
Human Immunodeficiency Virus 1 Post-attachment Fusion Inhibitor [EPC] 245
beta2-Adrenergic Agonist [EPC] 245
Carboxypeptidase [EPC] 239
Human Blood Coagulation Factor [EPC] 236
Vitamin B6 Analog [EPC] 229
Tubulin Inhibiting Agent [EPC] 223
Antileishmanial [EPC] 222
CD123 Interaction [EPC] 219
Cytotoxin [EPC] 219
Antidiarrheal [EPC] 184
Polyene Antimicrobial [EPC] 167
Cholecystokinin Analog [EPC] 140
Cytomegalovirus pUL97 Kinase Inhibitor [EPC] 126
Nonsteroidal Mineralocorticoid-Receptor Antagonist [EPC] 121
Streptogramin Antibacterial [EPC] 104
Amyloid Beta-directed Antibody [EPC] 94
Standardized Insect Allergenic Extract [EPC] 79
Human Immunoglobulin [EPC] 77
Inactivated Influenza B Virus Vaccine [EPC] 72
Nitrogen Binding Agent [EPC] 66
Cyclooxygenase Inhibitor [EPC] 64
alpha-1 Adrenergic Agonist [EPC] 64
Sucrose-specific Enzyme [EPC] 58
Sphingosine 1-phosphate Receptor Modulator [EPC] 56
Lead Chelator [EPC] 54
Type I Interferon Receptor Antagonist [EPC] 54
Non-Standardized Animal Skin Allergenic Extract [EPC] 49
Partial Opioid Agonist/Antagonist [EPC] 47
Farnesyltransferase Inhibitor [EPC] 46
Interferon gamma Blocker [EPC] 46
Urease Inhibitor [EPC] 46
Folate Analog [EPC] 44
Catecholamine Synthesis Inhibitor [EPC] 38
l-Triiodothyronine [EPC] 37
Omega-3 Fatty Acid [EPC] 36
Lysosomal beta Glucuronidase [EPC] 34
Interferon alfa-2b [EPC] 33
Renal Dehydropeptidase Inhibitor [EPC] 32
Complement 5a Receptor Antagonist [EPC] 31
Angiopoietin-like 3 Inhibitor [EPC] 29
Metal Chelator [EPC] 26
Melanocortin 4 Receptor Agonist [EPC] 23
Non-Standardized Animal Hair Allergenic Extract [EPC] 17
Recombinant Antithrombin [EPC] 16
Non-Standardized Feather Allergenic Extract [EPC] 13
Interleukin-13 Antagonist [EPC] 11
Ileal Bile Acid Transporter Inhibitor [EPC] 9
Inhalation Diagnostic Agent [EPC] 8
Bispecific gp100 Peptide-HLA-directed CD3 T Cell Engager [EPC] 6
Growth Hormone Secretagogue Receptor Agonist [EPC] 5
Decorporation Agent [EPC] 4
Live Vaccinia Virus Vaccine [EPC] 4
Anthrax Protective Antigen-directed Antibody [EPC] 1
Classical Complement Pathway Inhibitor [EPC] 1
Non-Standardized Plant Fiber Allergenic Extract [EPC] 1