Drug Side Effects

Most commonly reported drug classes:

Drug class Count
Nonsteroidal Anti-inflammatory Drug [EPC] 925747
Corticosteroid [EPC] 915504
Tumor Necrosis Factor Blocker [EPC] 806700
Benzodiazepine [EPC] 572253
Platelet Aggregation Inhibitor [EPC] 483613
Anti-epileptic Agent [EPC] 453806
Proton Pump Inhibitor [EPC] 448118
Atypical Antipsychotic [EPC] 405573
Kinase Inhibitor [EPC] 385475
Thalidomide Analog [EPC] 381386
Insulin Analog [EPC] 368639
Factor Xa Inhibitor [EPC] 350730
Folate Analog Metabolic Inhibitor [EPC] 327346
HMG-CoA Reductase Inhibitor [EPC] 302062
Histamine-2 Receptor Antagonist [EPC] 299878
Provitamin D2 Compound [EPC] 285079
Angiotensin 2 Receptor Blocker [EPC] 261746
Vitamin B12 [EPC] 256916
Vitamin C [EPC] 256217
Progestin [EPC] 242308
Dihydropyridine Calcium Channel Blocker [EPC] 242141
Vitamin D [EPC] 241582
Loop Diuretic [EPC] 226785
beta-Adrenergic Blocker [EPC] 222368
Retinoid [EPC] 219628
Nucleoside Metabolic Inhibitor [EPC] 216161
Integrin Receptor Antagonist [EPC] 210920
Opioid Agonist [EPC] 207191
GLP-1 Receptor Agonist [EPC] 200519
Calcium Channel Blocker [EPC] 196709
Interferon beta [EPC] 194019
CD20-directed Cytolytic Antibody [EPC] 188943
Thiazide Diuretic [EPC] 182202
Progestin-containing Intrauterine Device [EPC] 175880
Platinum-based Drug [EPC] 175274
Alkylating Drug [EPC] 174900
Mood Stabilizer [EPC] 172231
Osmotic Laxative [EPC] 166990
RANK Ligand Inhibitor [EPC] 165238
Endothelin Receptor Antagonist [EPC] 159378
Estrogen [EPC] 155475
Expectorant [EPC] 145390
Vascular Endothelial Growth Factor Inhibitor [EPC] 136753
Interleukin-17A Antagonist [EPC] 135411
l-Thyroxine [EPC] 134563
Xanthine Oxidase Inhibitor [EPC] 133070
Programmed Death Receptor-1 Blocking Antibody [EPC] 129205
Sulfonylurea [EPC] 127925
Interleukin-4 Receptor alpha Antagonist [EPC] 126923
Phosphate Binder [EPC] 118995
Calcium [EPC] 116621
Angiotensin Converting Enzyme Inhibitor [EPC] 115588
Azole Antifungal [EPC] 113299
PCSK9 Inhibitor [EPC] 113110
Microtubule Inhibitor [EPC] 109646
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 109459
Leukocyte Growth Factor [EPC] 108859
Aldosterone Antagonist [EPC] 108818
Parathyroid Hormone Analog [EPC] 105174
Quinolone Antimicrobial [EPC] 102813
Selective T Cell Costimulation Modulator [EPC] 100570
Phosphodiesterase 5 Inhibitor [EPC] 100183
Aminosalicylate [EPC] 95359
Prostacycline Vasodilator [EPC] 95215
Interleukin-23 Antagonist [EPC] 93066
Interleukin-6 Receptor Antagonist [EPC] 87990
Proteasome Inhibitor [EPC] 84306
Serotonin-3 Receptor Antagonist [EPC] 84011
Antirheumatic Agent [EPC] 83649
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 82551
Aromatase Inhibitor [EPC] 81234
Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 80887
Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 80591
Calcineurin Inhibitor Immunosuppressant [EPC] 80432
alpha-Adrenergic Blocker [EPC] 79111
Nucleoside Analog Antiviral [EPC] 78060
Partial Opioid Agonist [EPC] 77384
Nitrate Vasodilator [EPC] 75758
Prostaglandin Analog [EPC] 75531
Dihydrofolate Reductase Inhibitor Antibacterial [EPC] 71654
Antiarrhythmic [EPC] 70627
gamma-Aminobutyric Acid-ergic Agonist [EPC] 70103
Interleukin-12 Antagonist [EPC] 69769
Purine Antimetabolite [EPC] 68023
Serotonin Reuptake Inhibitor [EPC] 67302
Acetylcholine Release Inhibitor [EPC] 66731
Neuromuscular Blocker [EPC] 66535
Potassium Channel Blocker [EPC] 66249
Peroxisome Proliferator Receptor alpha Agonist [EPC] 65467
Cardiac Glycoside [EPC] 64535
Erythropoiesis-stimulating Agent [EPC] 64474
Dietary Cholesterol Absorption Inhibitor [EPC] 64363
Potassium Salt [EPC] 64184
Sulfonamide Antimicrobial [EPC] 63069
Central Nervous System Stimulant [EPC] 62623
Androgen Receptor Inhibitor [EPC] 61075
Nicotinic Acid [EPC] 60322
Amide Local Anesthetic [EPC] 59170
mTOR Inhibitor Immunosuppressant [EPC] 57729
5-alpha Reductase Inhibitor [EPC] 57246
Interferon alpha [EPC] 56780
Cytochrome P450 3A Inhibitor [EPC] 53928
Cholinergic Nicotinic Agonist [EPC] 53060
Catecholamine [EPC] 52688
Nitroimidazole Antimicrobial [EPC] 52207
Topoisomerase Inhibitor [EPC] 50888
HER2/neu Receptor Antagonist [EPC] 50826
Anti-IgE [EPC] 50358
Vitamin A [EPC] 50103
Janus Kinase Inhibitor [EPC] 48110
Aromatic Amino Acid [EPC] 46729
Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 46231
alpha-Adrenergic Agonist [EPC] 46209
beta-Adrenergic Agonist [EPC] 46208
Glycopeptide Antibacterial [EPC] 45767
Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 45538
Tetracycline-class Drug [EPC] 45185
Central alpha-2 Adrenergic Agonist [EPC] 45130
Complement Inhibitor [EPC] 44770
Insulin [EPC] 44567
Hepatitis C Virus NS5A Inhibitor [EPC] 44304
Aromatic Amino Acid Decarboxylation Inhibitor [EPC] 41623
Methylxanthine [EPC] 40291
Protease Inhibitor [EPC] 40094
Macrolide Antimicrobial [EPC] 39904
Androgen [EPC] 39719
Pyrimidine Synthesis Inhibitor [EPC] 39114
Epidermal Growth Factor Receptor Antagonist [EPC] 36941
Serotonin-1b and Serotonin-1d Receptor Agonist [EPC] 35541
Sodium-Glucose Cotransporter 2 Inhibitor [EPC] 34214
Histamine-1 Receptor Antagonist [EPC] 34170
Muscle Relaxant [EPC] 33901
Polyene Antifungal [EPC] 32993
Pyridone [EPC] 32659
Aminoglycoside Antibacterial [EPC] 31844
Copper-containing Intrauterine Device [EPC] 31785
Thiazide-like Diuretic [EPC] 31427
General Anesthetic [EPC] 31148
CTLA-4-directed Blocking Antibody [EPC] 31124
Arteriolar Vasodilator [EPC] 30879
Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor [EPC] 30821
Cholinergic Muscarinic Antagonist [EPC] 30354
BCL-2 Inhibitor [EPC] 29290
Sympathomimetic-like Agent [EPC] 27561
beta3-Adrenergic Agonist [EPC] 26843
Iron Chelator [EPC] 25657
Interleukin-5 Antagonist [EPC] 25006
Intestinal Lipase Inhibitor [EPC] 24629
P2Y12 Platelet Inhibitor [EPC] 24508
Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 24331
CD38-directed Cytolytic Antibody [EPC] 23698
Lincosamide Antibacterial [EPC] 23371
Soluble Guanylate Cyclase Stimulator [EPC] 22670
Rifamycin Antibacterial [EPC] 21070
Estrogen Receptor Antagonist [EPC] 21060
Phenothiazine [EPC] 20952
Alkaloid [EPC] 20915
Oxazolidinone Antibacterial [EPC] 19780
Nitrofuran Antibacterial [EPC] 19506
Typical Antipsychotic [EPC] 18955
Guanylate Cyclase-C Agonist [EPC] 18388
Aluminum Complex [EPC] 18292
Prostacyclin Receptor Agonist [EPC] 17903
Radiographic Contrast Agent [EPC] 17124
B Lymphocyte Stimulator-specific Inhibitor [EPC] 17095
Anti-anginal [EPC] 16760
CD52-directed Cytolytic Antibody [EPC] 16360
Potassium-sparing Diuretic [EPC] 16293
Leukotriene Receptor Antagonist [EPC] 16266
Recombinant Human Deoxyribonuclease 1 [EPC] 16249
Antimetabolite [EPC] 15460
Carbonic Anhydrase Inhibitor [EPC] 15388
Vitamin D3 Analog [EPC] 15235
Vitamin D2 Analog [EPC] 14965
Dipeptidyl Peptidase 4 Inhibitor [EPC] 14832
Prostaglandin E1 Analog [EPC] 14817
Antimycobacterial [EPC] 14664
Substance P/Neurokinin-1 Receptor Antagonist [EPC] 14501
Hepatitis C Virus NS3/4A Protease Inhibitor [EPC] 14497
Progesterone [EPC] 14470
Cholinesterase Inhibitor [EPC] 14343
Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 14029
Macrolide [EPC] 13914
Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor [EPC] 13889
Potassium Binder [EPC] 13701
Cystic Fibrosis Transmembrane Conductance Regulator Potentiator [EPC] 13626
Bile Acid [EPC] 13356
Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] 12865
Lipid-based Polyene Antifungal [EPC] 12511
Standardized Chemical Allergen [EPC] 12235
Non-Standardized Food Allergenic Extract [EPC] 12193
Recombinant Human Growth Hormone [EPC] 12179
Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC] 12133
Phosphodiesterase 4 Inhibitor [EPC] 12042
Thrombopoietin Receptor Agonist [EPC] 12016
Parathyroid Hormone-Related Peptide Analog [EPC] 11928
Orexin Receptor Antagonist [EPC] 11874
Interleukin-1 Receptor Antagonist [EPC] 11704
Influenza A M2 Protein Inhibitor [EPC] 11513
Anticholinergic [EPC] 11510
Lymphocyte Function-Associated Antigen-1 Antagonist [EPC] 11113
Nonergot Dopamine Agonist [EPC] 11107
Melatonin Receptor Agonist [EPC] 10938
Lipopeptide Antibacterial [EPC] 10812
Non-narcotic Antitussive [EPC] 10793
Stimulant Laxative [EPC] 10279
Barbiturate [EPC] 9964
Antimetabolite Immunosuppressant [EPC] 9842
Non-Standardized Plant Allergenic Extract [EPC] 9840
Catechol-O-Methyltransferase Inhibitor [EPC] 9799
Asparagine-specific Enzyme [EPC] 9700
Prostacycline [EPC] 9569
Parenteral Iron Replacement [EPC] 9566
SARS-CoV-2 Nucleotide Analog RNA Polymerase Inhibitor [EPC] 9230
Programmed Death Ligand-1 Blocker [EPC] 9065
Non-Standardized Chemical Allergen [EPC] 8560
Antidote [EPC] 8552
RNA Synthetase Inhibitor Antibacterial [EPC] 8440
Bile Acid Sequestrant [EPC] 8375
Antiprotozoal [EPC] 8354
Vasopressin V2 Receptor Antagonist [EPC] 8300
GLP-2 Analog [EPC] 8238
Interleukin-2 Receptor Blocking Antibody [EPC] 8153
Interleukin-5 Receptor alpha-directed Cytolytic Antibody [EPC] 7649
Chloride Channel Activator [EPC] 7594
Sulfone [EPC] 7470
Cannabinoid [EPC] 7442
Hedgehog Pathway Inhibitor [EPC] 7279
Vesicular Monoamine Transporter 2 Inhibitor [EPC] 6899
Peroxisome Proliferator Receptor gamma Agonist [EPC] 6891
Thiazolidinedione [EPC] 6891
Hydrolytic Lysosomal Neutral Glycosphingolipid-specific Enzyme [EPC] 6829
Antifibrinolytic Agent [EPC] 6716
Vitamin K [EPC] 6600
Warfarin Reversal Agent [EPC] 6600
Antisense Oligonucleotide [EPC] 6528
Glinide [EPC] 6522
Antimalarial [EPC] 6406
Cephalosporin Antibacterial [EPC] 6371
Immunoglobulin G [EPC] 6283
Sigma-1 Agonist [EPC] 6135
Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC] 6135
CD30-directed Immunoconjugate [EPC] 6124
Human Immunoglobulin G [EPC] 5970
Adenosine Receptor Agonist [EPC] 5855
Thyroid Hormone Synthesis Inhibitor [EPC] 5835
Antidote for Acetaminophen Overdose [EPC] 5694
Mucolytic [EPC] 5694
Hydrolytic Lysosomal Glucocerebroside-specific Enzyme [EPC] 5677
Farnesoid X Receptor Agonist [EPC] 5627
Anti-coagulant [EPC] 5514
Echinocandin Antifungal [EPC] 5121
Dopamine-2 Receptor Antagonist [EPC] 5115
Standardized Insect Venom Allergenic Extract [EPC] 5102
Survival Motor Neuron-2-directed RNA Interaction [EPC] 5098
Phosphodiesterase 3 Inhibitor [EPC] 4959
Tissue-nonspecific Alkaline Phosphatase [EPC] 4837
Tetracycline-class Antibacterial [EPC] 4527
Vascular Endothelial Growth Factor Receptor 2 Antagonist [EPC] 4485
Prostaglandin E1 Agonist [EPC] 4480
Pediculicide [EPC] 4463
Bismuth [EPC] 4458
Noncompetitive AMPA Glutamate Receptor Antagonist [EPC] 4450
Antiparasitic [EPC] 4338
Parathyroid Hormone [EPC] 4295
SLAMF7-directed Immunostimulatory Antibody [EPC] 4275
Phenylalanine Metabolizing Enzyme [EPC] 4198
Contrast Agent for Ultrasound Imaging [EPC] 4197
Paramagnetic Contrast Agent [EPC] 4195
Recombinant Human Nerve Growth Factor [EPC] 4098
Somatostatin Analog [EPC] 4074
Amino Acid [EPC] 3972
Non-Standardized Insect Allergenic Extract [EPC] 3882
Vitamin D Analog [EPC] 3796
Osmotic Diuretic [EPC] 3773
Gadolinium-based Contrast Agent [EPC] 3646
beta Lactamase Inhibitor [EPC] 3646
alpha-Glucosidase Inhibitor [EPC] 3638
Ergot Derivative [EPC] 3635
Direct Thrombin Inhibitor [EPC] 3569
Progestin Antagonist [EPC] 3440
Antiseptic [EPC] 3204
Blood Viscosity Reducer [EPC] 3078
Non-Standardized Fungal Allergenic Extract [EPC] 3070
CD33-directed Immunoconjugate [EPC] 3023
Sulfonamide Antibacterial [EPC] 2960
Selective T Cell Costimulation Blocker [EPC] 2932
Plasma Kallikrein Inhibitor [EPC] 2866
Calcitonin [EPC] 2824
Antihypoglycemic Agent [EPC] 2710
Gastrointestinal Motility Inhibitor [EPC] 2709
Histone Deacetylase Inhibitor [EPC] 2641
Neuraminidase Inhibitor [EPC] 2584
Cholinergic Receptor Agonist [EPC] 2552
Partial Cholinergic Nicotinic Agonist [EPC] 2552
Calcitonin Gene-related Peptide Receptor Antagonist [EPC] 2535
Estrogen Agonist/Antagonist [EPC] 2531
Monoamine Oxidase Inhibitor [EPC] 2519
mu-Opioid Receptor Agonist [EPC] 2514
Monoamine Oxidase Type B Inhibitor [EPC] 2450
Rifamycin Antimycobacterial [EPC] 2302
Gonadotropin Releasing Hormone Receptor Antagonist [EPC] 2296
Vasodilator [EPC] 2249
Actinomycin [EPC] 2223
Anthelmintic [EPC] 2197
Plasma Volume Expander [EPC] 2176
Oxytocic [EPC] 2132
Carnitine Analog [EPC] 2120
Human Platelet-derived Growth Factor [EPC] 2107
Skin Test Antigen [EPC] 2045
Tuberculosis Skin Test [EPC] 2045
Monobactam Antibacterial [EPC] 2024
Serotonin and Norepinephrine Reuptake Inhibitor [EPC] 2011
CCR5 Co-receptor Antagonist [EPC] 1975
Cytolytic Agent [EPC] 1952
Calculi Dissolution Agent [EPC] 1945
Hydrolytic Lysosomal Glycogen-specific Enzyme [EPC] 1886
Calcitonin Gene-related Peptide Antagonist [EPC] 1793
CD22-directed Immunoconjugate [EPC] 1777
Reducing and Complexing Thiol [EPC] 1765
Sphingosine 1-phosphate Receptor Modulator [EPC] 1718
Glucosylceramide Synthase Inhibitor [EPC] 1716
Endoglycosidase [EPC] 1697
Lipid Emulsion [EPC] 1697
Insulin-like Growth Factor-1 Receptor Inhibitor [EPC] 1694
Uric Acid-specific Enzyme [EPC] 1668
Macrolide Antibacterial [EPC] 1656
Benzothiazole [EPC] 1522
Photoenhancer [EPC] 1453
Live Attenuated Bacillus Calmette-Guerin Immunotherapy [EPC] 1406
Live Attenuated Bacillus Calmette-Guerin Vaccine [EPC] 1406
Pyrethroid [EPC] 1342
Penem Antibacterial [EPC] 1332
Gonadotropin [EPC] 1304
Radioactive Diagnostic Agent [EPC] 1297
Interferon gamma [EPC] 1275
Humanized Monoclonal Antibody Fragment [EPC] 1273
Cytomegalovirus DNA Terminase Complex Inhibitor [EPC] 1259
gamma-Aminobutyric Acid A Receptor Agonist [EPC] 1253
alpha-Hydroxy Acid [EPC] 1231
Hematopoietic Stem Cell Mobilizer [EPC] 1114
Anthracycline Topoisomerase Inhibitor [EPC] 1000
Surfactant [EPC] 989
Interleukin-17 Receptor A Antagonist [EPC] 985
Dihydrofolate Reductase Inhibitor Antimalarial [EPC] 980
Lymphocyte Growth Factor [EPC] 879
Melanin Synthesis Inhibitor [EPC] 863
Leptin Analog [EPC] 822
Adrenocorticotropic Hormone [EPC] 821
Chemokine Receptor Type 4 Interaction [EPC] 814
Monoclonal Antibody [EPC] 814
4-Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor [EPC] 799
Lipoglycopeptide Antibacterial [EPC] 785
Nucleoside Analog Antifungal [EPC] 780
Adenosine Triphosphate-Citrate Lyase Inhibitor [EPC] 770
Aldehyde Dehydrogenase Inhibitor [EPC] 770
Thyroid Stimulating Hormone [EPC] 746
Oxaborole Antifungal [EPC] 742
Methylating Agent [EPC] 737
Pleuromutilin Antibacterial [EPC] 712
Opioid Antagonist [EPC] 630
Glycolipid Disialoganglioside-directed Antibody [EPC] 601
Benzodiazepine Antagonist [EPC] 579
Photoactivated Radical Generator [EPC] 553
Psoralen [EPC] 553
5-Lipoxygenase Inhibitor [EPC] 527
Adrenal Steroid Synthesis Inhibitor [EPC] 517
Hydrolytic Lysosomal Cholesteryl Ester-specific Enzyme [EPC] 469
Hydrolytic Lysosomal Triacylglycerol-specific Enzyme [EPC] 469
Ester Local Anesthetic [EPC] 446
Cytomegalovirus pUL97 Kinase Inhibitor [EPC] 423
Tricyclic Antidepressant [EPC] 396
Mucocutaneous Epithelial Cell Growth Factor [EPC] 370
beta2-Adrenergic Agonist [EPC] 347
Nonsteroidal Mineralocorticoid-Receptor Antagonist [EPC] 337
Interleukin-13 Antagonist [EPC] 309
Interleukin-6 Antagonist [EPC] 294
CD4-directed Blocking Antibody [EPC] 293
Human Immunodeficiency Virus 1 Post-attachment Fusion Inhibitor [EPC] 293
Non-Standardized Pollen Allergenic Extract [EPC] 285
Standardized Pollen Allergenic Extract [EPC] 285
Complement 5a Receptor Antagonist [EPC] 262
Carboxypeptidase [EPC] 251
CD123 Interaction [EPC] 247
Cytotoxin [EPC] 247
Interferon alfa-2b [EPC] 244
Human Blood Coagulation Factor [EPC] 243
Amyloid Beta-directed Antibody [EPC] 240
Tubulin Inhibiting Agent [EPC] 240
Vitamin B6 Analog [EPC] 239
Antidiarrheal [EPC] 201
Polyene Antimicrobial [EPC] 188
Type I Interferon Receptor Antagonist [EPC] 153
Vasoconstrictor [EPC] 143
Cholecystokinin Analog [EPC] 141
Streptogramin Antibacterial [EPC] 104
Standardized Insect Allergenic Extract [EPC] 85
Inactivated Influenza B Virus Vaccine [EPC] 79
Human Immunoglobulin [EPC] 78
Sucrose-specific Enzyme [EPC] 66
Bispecific gp100 Peptide-HLA-directed CD3 T Cell Engager [EPC] 65
Cyclooxygenase Inhibitor [EPC] 64
Nitrogen Binding Agent [EPC] 64
alpha-1 Adrenergic Agonist [EPC] 64
Lead Chelator [EPC] 60
Interferon gamma Blocker [EPC] 56
Non-Standardized House Dust Allergenic Extract [EPC] 52
Non-Standardized Animal Skin Allergenic Extract [EPC] 51
Partial Opioid Agonist/Antagonist [EPC] 47
Urease Inhibitor [EPC] 47
Angiopoietin-like 3 Inhibitor [EPC] 45
Ileal Bile Acid Transporter Inhibitor [EPC] 44
Catecholamine Synthesis Inhibitor [EPC] 41
l-Triiodothyronine [EPC] 39
Renal Dehydropeptidase Inhibitor [EPC] 35
Lysosomal beta Glucuronidase [EPC] 34
Melanocortin 4 Receptor Agonist [EPC] 31
Metal Chelator [EPC] 28
Lymphocyte Activation Gene-3 Blocker [EPC] 24
Cortisol Synthesis Inhibitor [EPC] 19
Non-Standardized Animal Hair Allergenic Extract [EPC] 17
Standardized Animal Hair Allergenic Extract [EPC] 17
Carbamoyl Phosphate Synthetase 1 Activator [EPC] 14
Non-Standardized Feather Allergenic Extract [EPC] 13
Classical Complement Pathway Inhibitor [EPC] 11
Orthopoxvirus VP37 Envelope Wrapping Protein Inhibitor [EPC] 11
Inhalation Diagnostic Agent [EPC] 8
Growth Hormone Secretagogue Receptor Agonist [EPC] 5
Decorporation Agent [EPC] 4
Live Vaccinia Virus Vaccine [EPC] 4
Folate Analog [EPC] 3
Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] 3
Small Interfering RNA [EPC] 3
Transthyretin-directed RNA Interaction [EPC] 3
Anthrax Protective Antigen-directed Antibody [EPC] 2
Non-Standardized Plant Fiber Allergenic Extract [EPC] 1
Omega-3 Fatty Acid [EPC] 1