Drug Side Effects

Most commonly reported drug classes:

Drug class Count
Nonsteroidal Anti-inflammatory Drug [EPC] 1019806
Corticosteroid [EPC] 895274
Tumor Necrosis Factor Blocker [EPC] 794986
Platelet Aggregation Inhibitor [EPC] 595753
Benzodiazepine [EPC] 562698
Anti-epileptic Agent [EPC] 445380
Proton Pump Inhibitor [EPC] 438972
Atypical Antipsychotic [EPC] 396247
Kinase Inhibitor [EPC] 377878
Thalidomide Analog [EPC] 368744
Insulin Analog [EPC] 362359
Loop Diuretic [EPC] 344090
Factor Xa Inhibitor [EPC] 340157
HMG-CoA Reductase Inhibitor [EPC] 334489
Folate Analog Metabolic Inhibitor [EPC] 319703
Histamine-2 Receptor Antagonist [EPC] 293753
Provitamin D2 Compound [EPC] 269631
Angiotensin 2 Receptor Blocker [EPC] 253831
Vitamin B12 [EPC] 251909
Vitamin C [EPC] 251860
beta-Adrenergic Blocker [EPC] 251130
Progestin [EPC] 239325
Vitamin D [EPC] 237501
Dihydropyridine Calcium Channel Blocker [EPC] 236649
Retinoid [EPC] 217989
Opioid Agonist [EPC] 211224
Nucleoside Metabolic Inhibitor [EPC] 209817
Integrin Receptor Antagonist [EPC] 207604
Central Nervous System Stimulant [EPC] 198032
GLP-1 Receptor Agonist [EPC] 194053
Interferon beta [EPC] 192940
Calcium Channel Blocker [EPC] 192028
Thiazide Diuretic [EPC] 179455
CD20-directed Cytolytic Antibody [EPC] 178654
Methylxanthine [EPC] 178152
Progestin-containing Intrauterine Device [EPC] 174023
Alkylating Drug [EPC] 171075
Platinum-based Drug [EPC] 169781
Mood Stabilizer [EPC] 169167
Osmotic Laxative [EPC] 163398
RANK Ligand Inhibitor [EPC] 162759
Endothelin Receptor Antagonist [EPC] 155953
Estrogen [EPC] 153336
Expectorant [EPC] 141561
Vascular Endothelial Growth Factor Inhibitor [EPC] 134103
l-Thyroxine [EPC] 130229
Xanthine Oxidase Inhibitor [EPC] 129881
Interleukin-17A Antagonist [EPC] 129701
Sulfonylurea [EPC] 126681
Programmed Death Receptor-1 Blocking Antibody [EPC] 122206
Phosphate Binder [EPC] 116630
Calcium [EPC] 114288
Angiotensin Converting Enzyme Inhibitor [EPC] 113209
Interleukin-4 Receptor alpha Antagonist [EPC] 112341
Azole Antifungal [EPC] 110830
alpha-Adrenergic Blocker [EPC] 109970
PCSK9 Inhibitor [EPC] 109007
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 108536
Microtubule Inhibitor [EPC] 106440
Aldosterone Antagonist [EPC] 106197
Leukocyte Growth Factor [EPC] 106018
Parathyroid Hormone Analog [EPC] 104826
Quinolone Antimicrobial [EPC] 100160
Phosphodiesterase 5 Inhibitor [EPC] 98320
Selective T Cell Costimulation Modulator [EPC] 97206
Nicotinic Acid [EPC] 93589
Prostacycline Vasodilator [EPC] 92807
Aminosalicylate [EPC] 92190
Nucleoside Analog Antiviral [EPC] 91372
Interleukin-23 Antagonist [EPC] 87314
Interleukin-6 Receptor Antagonist [EPC] 83834
Proteasome Inhibitor [EPC] 81902
Antirheumatic Agent [EPC] 81466
Serotonin-3 Receptor Antagonist [EPC] 81239
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 79840
Aromatase Inhibitor [EPC] 79119
Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 78213
Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 77920
Calcineurin Inhibitor Immunosuppressant [EPC] 77611
Partial Opioid Agonist [EPC] 76684
Prostaglandin Analog [EPC] 74436
Nitrate Vasodilator [EPC] 74418
Dihydrofolate Reductase Inhibitor Antibacterial [EPC] 70133
Antiarrhythmic [EPC] 69272
gamma-Aminobutyric Acid-ergic Agonist [EPC] 68774
Interleukin-12 Antagonist [EPC] 67453
Serotonin Reuptake Inhibitor [EPC] 66275
Purine Antimetabolite [EPC] 66191
Acetylcholine Release Inhibitor [EPC] 65991
Potassium Channel Blocker [EPC] 65804
Neuromuscular Blocker [EPC] 65800
Peroxisome Proliferator Receptor alpha Agonist [EPC] 64578
Cardiac Glycoside [EPC] 64101
Erythropoiesis-stimulating Agent [EPC] 63614
Dietary Cholesterol Absorption Inhibitor [EPC] 63101
Potassium Salt [EPC] 62399
Sulfonamide Antimicrobial [EPC] 61726
Androgen Receptor Inhibitor [EPC] 59691
Amide Local Anesthetic [EPC] 57832
mTOR Inhibitor Immunosuppressant [EPC] 56732
Interferon alpha [EPC] 56650
5-alpha Reductase Inhibitor [EPC] 56128
Macrolide Antimicrobial [EPC] 55330
Vitamin A [EPC] 54131
Cytochrome P450 3A Inhibitor [EPC] 53299
Cholinergic Nicotinic Agonist [EPC] 52659
Catecholamine [EPC] 51242
Nitroimidazole Antimicrobial [EPC] 51077
HER2/neu Receptor Antagonist [EPC] 49963
Anti-IgE [EPC] 49573
Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor [EPC] 49544
Topoisomerase Inhibitor [EPC] 49219
Central alpha-2 Adrenergic Agonist [EPC] 46975
Janus Kinase Inhibitor [EPC] 46095
Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 45264
Aromatic Amino Acid [EPC] 45246
alpha-Adrenergic Agonist [EPC] 45034
beta-Adrenergic Agonist [EPC] 45033
Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 45007
Insulin [EPC] 44838
Glycopeptide Antibacterial [EPC] 44595
Complement Inhibitor [EPC] 44223
Tetracycline-class Drug [EPC] 43773
Hepatitis C Virus NS5A Inhibitor [EPC] 43740
Aromatic Amino Acid Decarboxylation Inhibitor [EPC] 40208
Protease Inhibitor [EPC] 39668
Androgen [EPC] 39150
Pyrimidine Synthesis Inhibitor [EPC] 37736
Epidermal Growth Factor Receptor Antagonist [EPC] 36399
Serotonin-1b and Serotonin-1d Receptor Agonist [EPC] 34925
Muscle Relaxant [EPC] 33495
Histamine-1 Receptor Antagonist [EPC] 33068
Polyene Antifungal [EPC] 32097
Sodium-Glucose Cotransporter 2 Inhibitor [EPC] 32094
Pyridone [EPC] 32040
Copper-containing Intrauterine Device [EPC] 31439
Cholinergic Muscarinic Antagonist [EPC] 31296
Aminoglycoside Antibacterial [EPC] 31091
General Anesthetic [EPC] 30709
Thiazide-like Diuretic [EPC] 30656
CTLA-4-directed Blocking Antibody [EPC] 30024
Sympathomimetic-like Agent [EPC] 27251
BCL-2 Inhibitor [EPC] 27172
beta3-Adrenergic Agonist [EPC] 25591
Arteriolar Vasodilator [EPC] 25539
Iron Chelator [EPC] 25389
Intestinal Lipase Inhibitor [EPC] 24553
P2Y12 Platelet Inhibitor [EPC] 24017
Interleukin-5 Antagonist [EPC] 23687
Lincosamide Antibacterial [EPC] 22902
Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 22873
CD38-directed Cytolytic Antibody [EPC] 22134
Soluble Guanylate Cyclase Stimulator [EPC] 21920
Alkaloid [EPC] 20393
Rifamycin Antibacterial [EPC] 20321
Phenothiazine [EPC] 20305
Estrogen Receptor Antagonist [EPC] 20265
Oxazolidinone Antibacterial [EPC] 19163
Nitrofuran Antibacterial [EPC] 19124
Vitamin D3 Analog [EPC] 18716
Typical Antipsychotic [EPC] 18552
Guanylate Cyclase-C Agonist [EPC] 18061
Aluminum Complex [EPC] 17905
Prostacyclin Receptor Agonist [EPC] 17333
Radiographic Contrast Agent [EPC] 16814
Anti-anginal [EPC] 16578
B Lymphocyte Stimulator-specific Inhibitor [EPC] 16275
Potassium-sparing Diuretic [EPC] 16154
CD52-directed Cytolytic Antibody [EPC] 16126
Recombinant Human Deoxyribonuclease 1 [EPC] 16001
Non-Standardized Food Allergenic Extract [EPC] 15619
Leukotriene Receptor Antagonist [EPC] 15523
Carbonic Anhydrase Inhibitor [EPC] 15056
Antimetabolite [EPC] 15040
Prostaglandin E1 Analog [EPC] 14646
Antimycobacterial [EPC] 14430
Dipeptidyl Peptidase 4 Inhibitor [EPC] 14329
Hepatitis C Virus NS3/4A Protease Inhibitor [EPC] 14251
Substance P/Neurokinin-1 Receptor Antagonist [EPC] 14158
Cholinesterase Inhibitor [EPC] 14116
Progesterone [EPC] 14087
Vitamin D2 Analog [EPC] 13708
Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor [EPC] 13699
Potassium Binder [EPC] 13612
Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 13560
Macrolide [EPC] 13514
Cystic Fibrosis Transmembrane Conductance Regulator Potentiator [EPC] 13444
Bile Acid [EPC] 12723
Anticholinergic [EPC] 12656
Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] 12512
Lipid-based Polyene Antifungal [EPC] 12067
Standardized Chemical Allergen [EPC] 12004
Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC] 11982
Parathyroid Hormone-Related Peptide Analog [EPC] 11876
Thrombopoietin Receptor Agonist [EPC] 11839
Phosphodiesterase 4 Inhibitor [EPC] 11794
Recombinant Human Growth Hormone [EPC] 11792
Orexin Receptor Antagonist [EPC] 11472
Influenza A M2 Protein Inhibitor [EPC] 11252
Interleukin-1 Receptor Antagonist [EPC] 11207
Nonergot Dopamine Agonist [EPC] 10836
Catechol-O-Methyltransferase Inhibitor [EPC] 10558
Lipopeptide Antibacterial [EPC] 10522
Non-narcotic Antitussive [EPC] 10506
Melatonin Receptor Agonist [EPC] 10331
Lymphocyte Function-Associated Antigen-1 Antagonist [EPC] 10279
Stimulant Laxative [EPC] 9977
Non-Standardized Plant Allergenic Extract [EPC] 9901
Barbiturate [EPC] 9806
Prostacycline [EPC] 9500
Asparagine-specific Enzyme [EPC] 9484
Parenteral Iron Replacement [EPC] 9265
Antimetabolite Immunosuppressant [EPC] 9162
SARS-CoV-2 Nucleotide Analog RNA Polymerase Inhibitor [EPC] 8570
Programmed Death Ligand-1 Blocker [EPC] 8543
Non-Standardized Chemical Allergen [EPC] 8486
Antidote [EPC] 8198
Bile Acid Sequestrant [EPC] 8142
RNA Synthetase Inhibitor Antibacterial [EPC] 8129
Antiprotozoal [EPC] 8068
Vasopressin V2 Receptor Antagonist [EPC] 8035
Interleukin-2 Receptor Blocking Antibody [EPC] 8001
GLP-2 Analog [EPC] 7728
Chloride Channel Activator [EPC] 7481
Cannabinoid [EPC] 7274
Sulfone [EPC] 7252
Interleukin-5 Receptor alpha-directed Cytolytic Antibody [EPC] 7232
Hedgehog Pathway Inhibitor [EPC] 7197
Vesicular Monoamine Transporter 2 Inhibitor [EPC] 6863
Peroxisome Proliferator Receptor gamma Agonist [EPC] 6719
Thiazolidinedione [EPC] 6719
Hydrolytic Lysosomal Neutral Glycosphingolipid-specific Enzyme [EPC] 6677
Antifibrinolytic Agent [EPC] 6440
Vitamin K [EPC] 6428
Warfarin Reversal Agent [EPC] 6428
Glinide [EPC] 6343
Cephalosporin Antibacterial [EPC] 6259
Immunoglobulin G [EPC] 6199
Antimalarial [EPC] 6132
Sigma-1 Agonist [EPC] 6069
Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC] 6069
Antisense Oligonucleotide [EPC] 6038
CD30-directed Immunoconjugate [EPC] 5888
Adenosine Receptor Agonist [EPC] 5833
Thyroid Hormone Synthesis Inhibitor [EPC] 5651
Hydrolytic Lysosomal Glucocerebroside-specific Enzyme [EPC] 5581
Farnesoid X Receptor Agonist [EPC] 5558
Antidote for Acetaminophen Overdose [EPC] 5462
Mucolytic [EPC] 5462
Anti-coagulant [EPC] 5420
Standardized Insect Venom Allergenic Extract [EPC] 5048
Dopamine-2 Receptor Antagonist [EPC] 4972
Human Immunoglobulin G [EPC] 4966
Echinocandin Antifungal [EPC] 4939
Survival Motor Neuron-2-directed RNA Interaction [EPC] 4926
Phosphodiesterase 3 Inhibitor [EPC] 4849
Tissue-nonspecific Alkaline Phosphatase [EPC] 4795
Prostaglandin E1 Agonist [EPC] 4428
Tetracycline-class Antibacterial [EPC] 4394
Pediculicide [EPC] 4363
Vascular Endothelial Growth Factor Receptor 2 Antagonist [EPC] 4331
Bismuth [EPC] 4326
Noncompetitive AMPA Glutamate Receptor Antagonist [EPC] 4272
Antiparasitic [EPC] 4242
Parathyroid Hormone [EPC] 4238
SLAMF7-directed Immunostimulatory Antibody [EPC] 4181
Paramagnetic Contrast Agent [EPC] 4178
Contrast Agent for Ultrasound Imaging [EPC] 4153
Phenylalanine Metabolizing Enzyme [EPC] 3990
Somatostatin Analog [EPC] 3881
Non-Standardized Insect Allergenic Extract [EPC] 3846
Amino Acid [EPC] 3711
Vitamin D Analog [EPC] 3697
Osmotic Diuretic [EPC] 3677
beta Lactamase Inhibitor [EPC] 3646
Ergot Derivative [EPC] 3579
alpha-Glucosidase Inhibitor [EPC] 3565
Gadolinium-based Contrast Agent [EPC] 3559
Direct Thrombin Inhibitor [EPC] 3521
Progestin Antagonist [EPC] 3357
Antiseptic [EPC] 3160
Blood Viscosity Reducer [EPC] 3007
Non-Standardized Fungal Allergenic Extract [EPC] 2974
CD33-directed Immunoconjugate [EPC] 2952
Sulfonamide Antibacterial [EPC] 2880
Selective T Cell Costimulation Blocker [EPC] 2852
Calcitonin [EPC] 2792
Plasma Kallikrein Inhibitor [EPC] 2773
Antihypoglycemic Agent [EPC] 2613
Gastrointestinal Motility Inhibitor [EPC] 2612
Neuraminidase Inhibitor [EPC] 2581
Histone Deacetylase Inhibitor [EPC] 2539
Estrogen Agonist/Antagonist [EPC] 2527
mu-Opioid Receptor Agonist [EPC] 2499
Monoamine Oxidase Inhibitor [EPC] 2498
Monoamine Oxidase Type B Inhibitor [EPC] 2429
Cholinergic Receptor Agonist [EPC] 2376
Partial Cholinergic Nicotinic Agonist [EPC] 2376
Recombinant Human Nerve Growth Factor [EPC] 2318
Rifamycin Antimycobacterial [EPC] 2226
Actinomycin [EPC] 2174
Anthelmintic [EPC] 2151
Human Platelet-derived Growth Factor [EPC] 2106
Vasodilator [EPC] 2087
Oxytocic [EPC] 2077
Carnitine Analog [EPC] 2040
Calcitonin Gene-related Peptide Receptor Antagonist [EPC] 2019
Skin Test Antigen [EPC] 2002
Tuberculosis Skin Test [EPC] 2002
Monobactam Antibacterial [EPC] 1978
Cytolytic Agent [EPC] 1950
CCR5 Co-receptor Antagonist [EPC] 1947
Serotonin and Norepinephrine Reuptake Inhibitor [EPC] 1914
Calculi Dissolution Agent [EPC] 1899
Hydrolytic Lysosomal Glycogen-specific Enzyme [EPC] 1789
Reducing and Complexing Thiol [EPC] 1718
CD22-directed Immunoconjugate [EPC] 1699
Lipid Emulsion [EPC] 1656
Glucosylceramide Synthase Inhibitor [EPC] 1649
Endoglycosidase [EPC] 1612
Macrolide Antibacterial [EPC] 1589
Uric Acid-specific Enzyme [EPC] 1574
Insulin-like Growth Factor-1 Receptor Inhibitor [EPC] 1539
Gonadotropin Releasing Hormone Receptor Antagonist [EPC] 1481
Calcitonin Gene-related Peptide Antagonist [EPC] 1463
Photoenhancer [EPC] 1452
Live Attenuated Bacillus Calmette-Guerin Immunotherapy [EPC] 1382
Live Attenuated Bacillus Calmette-Guerin Vaccine [EPC] 1382
Pyrethroid [EPC] 1321
Penem Antibacterial [EPC] 1314
Interferon gamma [EPC] 1274
Humanized Monoclonal Antibody Fragment [EPC] 1256
gamma-Aminobutyric Acid A Receptor Agonist [EPC] 1230
Gonadotropin [EPC] 1223
Radioactive Diagnostic Agent [EPC] 1196
alpha-Hydroxy Acid [EPC] 1188
Benzothiazole [EPC] 1172
Cytomegalovirus DNA Terminase Complex Inhibitor [EPC] 1161
Hematopoietic Stem Cell Mobilizer [EPC] 1110
Surfactant [EPC] 968
Dihydrofolate Reductase Inhibitor Antimalarial [EPC] 962
Interleukin-17 Receptor A Antagonist [EPC] 911
Lymphocyte Growth Factor [EPC] 871
Melanin Synthesis Inhibitor [EPC] 854
Polymyxin-class Antibacterial [EPC] 837
Leptin Analog [EPC] 812
Adrenocorticotropic Hormone [EPC] 803
4-Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor [EPC] 784
Chemokine Receptor Type 4 Interaction [EPC] 774
Monoclonal Antibody [EPC] 774
Nucleoside Analog Antifungal [EPC] 749
Aldehyde Dehydrogenase Inhibitor [EPC] 736
Oxaborole Antifungal [EPC] 736
Lipoglycopeptide Antibacterial [EPC] 732
Anthracycline Topoisomerase Inhibitor [EPC] 731
Methylating Agent [EPC] 728
Thyroid Stimulating Hormone [EPC] 727
Pleuromutilin Antibacterial [EPC] 711
Adenosine Triphosphate-Citrate Lyase Inhibitor [EPC] 653
Opioid Antagonist [EPC] 606
Glycolipid Disialoganglioside-directed Antibody [EPC] 575
Benzodiazepine Antagonist [EPC] 564
Photoactivated Radical Generator [EPC] 550
Psoralen [EPC] 550
5-Lipoxygenase Inhibitor [EPC] 517
Adrenal Steroid Synthesis Inhibitor [EPC] 509
Hydrolytic Lysosomal Cholesteryl Ester-specific Enzyme [EPC] 464
Hydrolytic Lysosomal Triacylglycerol-specific Enzyme [EPC] 464
Plasma Volume Expander [EPC] 464
Ester Local Anesthetic [EPC] 437
Carbamoyl Phosphate Synthetase 1 Activator [EPC] 431
Tricyclic Antidepressant [EPC] 392
Standardized Pollen Allergenic Extract [EPC] 371
Mucocutaneous Epithelial Cell Growth Factor [EPC] 369
Non-Standardized Pollen Allergenic Extract [EPC] 367
Sclerosing Agent [EPC] 328
beta2-Adrenergic Agonist [EPC] 287
Interleukin-6 Antagonist [EPC] 279
Cytomegalovirus pUL97 Kinase Inhibitor [EPC] 276
CD4-directed Blocking Antibody [EPC] 271
Human Immunodeficiency Virus 1 Post-attachment Fusion Inhibitor [EPC] 271
Carboxypeptidase [EPC] 250
Human Blood Coagulation Factor [EPC] 240
Nonsteroidal Mineralocorticoid-Receptor Antagonist [EPC] 233
Vitamin B6 Analog [EPC] 233
Tubulin Inhibiting Agent [EPC] 232
CD123 Interaction [EPC] 226
Cytotoxin [EPC] 226
Antileishmanial [EPC] 225
Antidiarrheal [EPC] 190
Polyene Antimicrobial [EPC] 181
Amyloid Beta-directed Antibody [EPC] 164
Interferon alfa-2b [EPC] 151
Vasoconstrictor [EPC] 142
Cholecystokinin Analog [EPC] 140
Standardized Animal Hair Allergenic Extract [EPC] 121
Interleukin-13 Antagonist [EPC] 117
Complement 5a Receptor Antagonist [EPC] 110
Type I Interferon Receptor Antagonist [EPC] 108
Streptogramin Antibacterial [EPC] 103
Sphingosine 1-phosphate Receptor Modulator [EPC] 90
Standardized Insect Allergenic Extract [EPC] 84
Human Immunoglobulin [EPC] 77
Inactivated Influenza B Virus Vaccine [EPC] 76
Nitrogen Binding Agent [EPC] 67
Cyclooxygenase Inhibitor [EPC] 64
Sucrose-specific Enzyme [EPC] 64
alpha-1 Adrenergic Agonist [EPC] 64
Lead Chelator [EPC] 57
Interferon gamma Blocker [EPC] 52
Non-Standardized House Dust Allergenic Extract [EPC] 51
Farnesyltransferase Inhibitor [EPC] 50
Non-Standardized Animal Skin Allergenic Extract [EPC] 50
Partial Opioid Agonist/Antagonist [EPC] 47
Urease Inhibitor [EPC] 46
Catecholamine Synthesis Inhibitor [EPC] 39
l-Triiodothyronine [EPC] 38
Lysosomal beta Glucuronidase [EPC] 34
Renal Dehydropeptidase Inhibitor [EPC] 34
Angiopoietin-like 3 Inhibitor [EPC] 33
Bispecific gp100 Peptide-HLA-directed CD3 T Cell Engager [EPC] 29
Ileal Bile Acid Transporter Inhibitor [EPC] 28
Metal Chelator [EPC] 26
Melanocortin 4 Receptor Agonist [EPC] 24
Non-Standardized Animal Hair Allergenic Extract [EPC] 17
Non-Standardized Feather Allergenic Extract [EPC] 13
Inhalation Diagnostic Agent [EPC] 8
Cortisol Synthesis Inhibitor [EPC] 6
Orthopoxvirus VP37 Envelope Wrapping Protein Inhibitor [EPC] 6
Growth Hormone Secretagogue Receptor Agonist [EPC] 5
Decorporation Agent [EPC] 4
Live Vaccinia Virus Vaccine [EPC] 4
Classical Complement Pathway Inhibitor [EPC] 3
Folate Analog [EPC] 3
Anthrax Protective Antigen-directed Antibody [EPC] 2
Non-Standardized Plant Fiber Allergenic Extract [EPC] 1
Omega-3 Fatty Acid [EPC] 1