Drug Side Effects

ACETAMINOPHEN

ACETAMINOPHEN was reported 445034 times

ACETAMINOPHEN is most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 BLOOD PRESSURE DIASTOLIC ABNORMAL 1876 0.7395
1 BLOOD PRESSURE SYSTOLIC ABNORMAL 1720 0.6998
2 ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY 454 0.6889
3 LUPUS VULGARIS 792 0.6740
4 ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE 4606 0.6566
5 RHEUMATIC FEVER 2807 0.6510
6 SWOLLEN JOINT COUNT INCREASED 1976 0.6418
7 DEEP VEIN THROMBOSIS POSTOPERATIVE 1242 0.6415
8 C-REACTIVE PROTEIN 568 0.6339
9 DUODENAL ULCER PERFORATION 4564 0.6299
10 FACET JOINT SYNDROME 1725 0.5541
11 EXPOSURE TO TOXIC AGENT 1706 0.5365
12 RHEUMATOID FACTOR POSITIVE 2920 0.5127
13 MUSCLE INJURY 3986 0.4920
14 ADJUSTMENT DISORDER WITH DEPRESSED MOOD 977 0.4910
15 SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE 2974 0.4681
16 HELICOBACTER INFECTION 4707 0.4677
17 X-RAY ABNORMAL 801 0.4546
18 FOLLICULITIS 4524 0.4437
19 DISLOCATION OF VERTEBRA 973 0.4429
20 PEMPHIGUS 5229 0.4261
21 HAND DEFORMITY 5416 0.4194
22 ANALGESIC DRUG LEVEL INCREASED 604 0.3784
23 AUTISM SPECTRUM DISORDER 2018 0.3739
24 RETINITIS 605 0.3671
25 PERIPHERAL VENOUS DISEASE 1405 0.3564
26 SYNOVITIS 6150 0.3453
27 C-REACTIVE PROTEIN ABNORMAL 2113 0.3342
28 PERICARDITIS 5346 0.3250
29 INFUSION SITE DISCHARGE 465 0.2755
30 GLOSSODYNIA 5431 0.2462
31 SEDATION COMPLICATION 593 0.2403
32 ACUTE HEPATIC FAILURE 3177 0.2367
33 BURSITIS 2775 0.2330
34 BLOOD PRESSURE DIASTOLIC DECREASED 1704 0.2328
35 IRRITABLE BOWEL SYNDROME 4860 0.2305
36 TEMPERATURE REGULATION DISORDER 486 0.2253
37 BONE EROSION 787 0.2251
38 INFUSION SITE PRURITUS 670 0.2177
39 HYPERPARATHYROIDISM SECONDARY 543 0.2174
40 NEPHROGENIC ANAEMIA 988 0.2141
41 INFUSION RELATED REACTION 13948 0.2140
42 LIP DRY 1883 0.2129
43 BLOOD PRESSURE DIASTOLIC INCREASED 974 0.2128
44 WOUND 5736 0.2090
45 BREAST CANCER STAGE III 1325 0.2086
46 INFUSION SITE BRUISING 430 0.2049
47 DRUG TOLERANCE DECREASED 566 0.2048
48 BLOOD PRESSURE SYSTOLIC INCREASED 3885 0.2010
49 HYPERCHOLESTEROLAEMIA 1884 0.1995
50 JOINT RANGE OF MOTION DECREASED 2626 0.1991
51 GRIP STRENGTH DECREASED 1705 0.1975
52 ONYCHOMADESIS 798 0.1946
53 INFUSION SITE HAEMORRHAGE 610 0.1907
54 BLOOD PRESSURE FLUCTUATION 4516 0.1901
55 WOUND INFECTION 2021 0.1884
56 CONTRAINDICATED PRODUCT ADMINISTERED 5530 0.1858
57 WHITE BLOOD CELLS URINE POSITIVE 337 0.1828
58 INFUSION SITE SWELLING 1087 0.1789
59 ONYCHOMYCOSIS 770 0.1781
60 LIVER INJURY 4236 0.1775
61 SYSTEMIC LUPUS ERYTHEMATOSUS 5949 0.1704
62 EAR PRURITUS 578 0.1682
63 LIVE BIRTH 1351 0.1644
64 HEPATIC CYTOLYSIS 1961 0.1626
65 POISONING DELIBERATE 1491 0.1624
66 IMPAIRED HEALING 5234 0.1615
67 FIBROMYALGIA 3849 0.1606
68 INFUSION SITE REACTION 455 0.1586
69 AUTOIMMUNE DISORDER 1471 0.1557
70 BLEPHAROSPASM 931 0.1520
71 INFUSION SITE ERYTHEMA 1233 0.1507
72 CREATININE RENAL CLEARANCE DECREASED 599 0.1507
73 MATERNAL EXPOSURE TIMING UNSPECIFIED 550 0.1498
74 SUSPECTED SUICIDE 700 0.1487
75 LOWER RESPIRATORY TRACT INFECTION 6590 0.1474
76 RADICULOPATHY 383 0.1470
77 INFUSION SITE PAIN 1824 0.1448
78 BODY TEMPERATURE DECREASED 1377 0.1405
79 RED BLOOD CELL SEDIMENTATION RATE INCREASED 1530 0.1397
80 PHYSICAL DECONDITIONING 344 0.1392
81 SCIATICA 2174 0.1389
82 HEPATIC NECROSIS 517 0.1385
83 CHRONIC SINUSITIS 504 0.1363
84 REBOUND ACID HYPERSECRETION 405 0.1338
85 ATTENTION DEFICIT HYPERACTIVITY DISORDER 536 0.1308
86 ARTHROPATHY 7139 0.1297
87 POOR VENOUS ACCESS 1298 0.1274
88 END STAGE RENAL DISEASE 2312 0.1272
89 WALKING AID USER 822 0.1257
90 NAIL DISORDER 1068 0.1246
91 RED CELL DISTRIBUTION WIDTH INCREASED 508 0.1238
92 HEPATIC ENZYME INCREASED 8303 0.1238
93 INFUSION SITE EXTRAVASATION 734 0.1195
94 THERAPEUTIC PRODUCT EFFECT DECREASED 5147 0.1175
95 TYPE 2 DIABETES MELLITUS 3882 0.1165
96 OBESITY 1827 0.1160
97 EXOSTOSIS 1041 0.1156
98 BRONCHIECTASIS 750 0.1141
99 FOOD ALLERGY 845 0.1133
100 INCORRECT DRUG ADMINISTRATION RATE 469 0.1124
101 MULTIPLE DRUG OVERDOSE 555 0.1117
102 BLISTER 6174 0.1117
103 HEART RATE DECREASED 3826 0.1099
104 INTENTIONAL OVERDOSE 6888 0.1095
105 COELIAC DISEASE 1059 0.1093
106 SINUSITIS 10940 0.1079
107 URINE ABNORMALITY 477 0.1077
108 BODY TEMPERATURE INCREASED 2155 0.1067
109 INTENTIONAL PRODUCT USE ISSUE 9164 0.1056
110 MULTIPLE ALLERGIES 817 0.1055
111 IRON DEFICIENCY 463 0.1055
112 PULMONARY FIBROSIS 1989 0.1054
113 RESPIRATORY RATE INCREASED 909 0.1034
114 STOMATITIS 6169 0.1030
115 RHEUMATOID ARTHRITIS 11488 0.1030
116 COMPLETED SUICIDE 8542 0.1029
117 OSTEOARTHRITIS 4311 0.1028
118 EXPOSURE DURING PREGNANCY 6233 0.1016
119 EAR PAIN 1936 0.1009
120 MONOCYTE COUNT INCREASED 362 0.1008
121 TOXICITY TO VARIOUS AGENTS 16634 0.1004
122 SEASONAL ALLERGY 1398 0.1003
123 METABOLIC ACIDOSIS 3125 0.1000
124 JOINT SWELLING 11833 0.0995
125 OXYGEN SATURATION DECREASED 5448 0.0989
126 NIGHT SWEATS 3144 0.0989
127 C-REACTIVE PROTEIN INCREASED 3547 0.0988
128 DISCOMFORT 5898 0.0986
129 PRESCRIBED OVERDOSE 1875 0.0982
130 RALES 559 0.0975
131 BLOOD CALCIUM DECREASED 1077 0.0967
132 MUSCLE SPASTICITY 1179 0.0963
133 BLOOD CHOLESTEROL INCREASED 4405 0.0957
134 PSORIATIC ARTHROPATHY 3790 0.0955
135 SWELLING 8774 0.0952
136 HIP ARTHROPLASTY 1423 0.0949
137 BACK INJURY 1013 0.0948
138 DRUG INTOLERANCE 8978 0.0945
139 LOWER LIMB FRACTURE 1779 0.0944
140 ATELECTASIS 903 0.0943
141 SPONDYLITIS 337 0.0941
142 CHRONIC KIDNEY DISEASE 7003 0.0926
143 ULCER HAEMORRHAGE 617 0.0924
144 LARYNGITIS 986 0.0920
145 JOINT DISLOCATION 955 0.0919
146 WEIGHT FLUCTUATION 933 0.0907
147 FOOT DEFORMITY 992 0.0906
148 GAIT INABILITY 2957 0.0905
149 CYTOKINE RELEASE SYNDROME 1678 0.0892
150 COAGULOPATHY 1454 0.0887
151 DRUG TOXICITY 1199 0.0880
152 MACULAR DEGENERATION 1030 0.0876
153 HEPATITIS ACUTE 557 0.0872
154 HEPATOTOXICITY 1897 0.0867
155 URINARY TRACT DISORDER 385 0.0867
156 BREATH SOUNDS ABNORMAL 420 0.0863
157 EAR INFECTION 2257 0.0862
158 VASCULAR DEVICE INFECTION 384 0.0862
159 DRUG-INDUCED LIVER INJURY 2622 0.0861
160 MOBILITY DECREASED 6020 0.0852
161 SPUTUM DISCOLOURED 789 0.0846
162 PRODUCT LABEL CONFUSION 484 0.0843
163 PROTHROMBIN TIME PROLONGED 498 0.0834
164 ILL-DEFINED DISORDER 5000 0.0833
165 BLOOD PRESSURE SYSTOLIC DECREASED 371 0.0831
166 IMMUNODEFICIENCY 1202 0.0827
167 MUSCULOSKELETAL STIFFNESS 7151 0.0827
168 INFLAMMATION 4186 0.0826
169 LIVER FUNCTION TEST INCREASED 1739 0.0826
170 RASH VESICULAR 388 0.0816
171 CARDIAC MURMUR 699 0.0814
172 UPPER RESPIRATORY TRACT INFECTION 3698 0.0812
173 WHEEZING 4729 0.0810
174 LUPUS-LIKE SYNDROME 696 0.0782
175 APLASTIC ANAEMIA 404 0.0781
176 HEPATIC ENCEPHALOPATHY 712 0.0772
177 ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED 386 0.0769
178 GASTROINTESTINAL DISORDER 6667 0.0764
179 MAJOR DEPRESSION 550 0.0761
180 LYMPHOCYTE COUNT DECREASED 1319 0.0756
181 KNEE ARTHROPLASTY 1554 0.0755
182 SKIN LACERATION 802 0.0752
183 TASTE DISORDER 1488 0.0752
184 ORTHOSTATIC HYPOTENSION 1291 0.0750
185 DRUG LEVEL BELOW THERAPEUTIC 406 0.0749
186 HEPATIC FAILURE 2230 0.0748
187 PERIPHERAL SWELLING 11275 0.0745
188 CONTUSION 7063 0.0744
189 JOINT EFFUSION 504 0.0738
190 SINUS CONGESTION 985 0.0738
191 BLOOD URIC ACID INCREASED 418 0.0734
192 RHINITIS 582 0.0731
193 CONGENITAL ANOMALY 561 0.0729
194 TOXIC EPIDERMAL NECROLYSIS 1082 0.0727
195 SUICIDE ATTEMPT 4344 0.0724
196 SKIN ABRASION 334 0.0724
197 HYPOPHOSPHATAEMIA 525 0.0724
198 SCOLIOSIS 443 0.0723
199 NASOPHARYNGITIS 13089 0.0718
200 ANAL FISSURE 378 0.0718
201 COVID-19 PNEUMONIA 842 0.0718
202 TENDERNESS 738 0.0716
203 THROAT IRRITATION 3150 0.0714
204 APHTHOUS ULCER 540 0.0713
205 MUSCULOSKELETAL PAIN 3716 0.0713
206 FEBRILE NEUTROPENIA 4621 0.0707
207 DELIRIUM 2400 0.0703
208 PROTEIN URINE PRESENT 344 0.0702
209 FOETAL DEATH 358 0.0700
210 RENAL TUBULAR NECROSIS 677 0.0697
211 SPINAL OSTEOARTHRITIS 606 0.0696
212 LIVER DISORDER 3040 0.0695
213 ACIDOSIS 523 0.0692
214 ORAL CANDIDIASIS 887 0.0691
215 OEDEMA 3690 0.0691
216 SLEEP DISORDER 4758 0.0689
217 BLOOD PRESSURE INCREASED 10381 0.0687
218 TROPONIN INCREASED 510 0.0685
219 BRAIN OEDEMA 850 0.0682
220 LUNG DISORDER 3279 0.0679
221 RESPIRATORY TRACT INFECTION 1738 0.0678
222 RESPIRATORY DEPRESSION 820 0.0678
223 ABDOMINAL TENDERNESS 332 0.0677
224 HYPOXIA 2343 0.0677
225 HAEMORRHAGIC STROKE 525 0.0677
226 NEUTROPHIL COUNT INCREASED 683 0.0673
227 INTERVERTEBRAL DISC DEGENERATION 611 0.0665
228 JOINT STIFFNESS 1712 0.0661
229 PRESCRIBED UNDERDOSE 1300 0.0660
230 ACUTE KIDNEY INJURY 9922 0.0660
231 HAEMATOCRIT DECREASED 1298 0.0659
232 ABDOMINAL DISCOMFORT 10847 0.0658
233 TUBULOINTERSTITIAL NEPHRITIS 1212 0.0656
234 FLANK PAIN 605 0.0655
235 SEDATION 1683 0.0654
236 HYPERTRANSAMINASAEMIA 439 0.0653
237 TOOTH INFECTION 847 0.0651
238 HEART RATE IRREGULAR 1459 0.0651
239 DEPRESSED LEVEL OF CONSCIOUSNESS 2530 0.0649
240 GENERAL PHYSICAL HEALTH DETERIORATION 7355 0.0649
241 SKIN INFECTION 714 0.0648
242 FAILURE TO THRIVE 333 0.0647
243 CONFUSIONAL STATE 10281 0.0643
244 HEPATITIS 1625 0.0643
245 INFECTION 9133 0.0642
246 TOOTH ABSCESS 646 0.0640
247 UPPER-AIRWAY COUGH SYNDROME 517 0.0639
248 PRODUCTIVE COUGH 2987 0.0639
249 NECK PAIN 3516 0.0637
250 INSURANCE ISSUE 932 0.0636
251 GINGIVAL PAIN 498 0.0634
252 CYSTITIS 1998 0.0633
253 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 2960 0.0631
254 SINUS DISORDER 1229 0.0628
255 BREAST CANCER STAGE II 520 0.0627
256 INJURY 4375 0.0627
257 MYOSITIS 555 0.0627
258 HEPATIC CIRRHOSIS 1152 0.0625
259 RESPIRATORY DISORDER 1834 0.0619
260 MATERNAL EXPOSURE DURING PREGNANCY 5374 0.0617
261 PULMONARY MASS 901 0.0614
262 NEURALGIA 1469 0.0614
263 LEUKOCYTOSIS 1094 0.0613
264 ASPIRATION 654 0.0612
265 DERMATITIS CONTACT 685 0.0611
266 GASTROOESOPHAGEAL REFLUX DISEASE 4836 0.0611
267 OSTEOPOROSIS 2474 0.0609
268 SENSORY LOSS 485 0.0609
269 MIGRAINE 5681 0.0607
270 OSTEOPENIA 913 0.0606
271 ULCER 952 0.0606
272 CLOSTRIDIUM DIFFICILE COLITIS 632 0.0603
273 LIGAMENT SPRAIN 586 0.0602
274 PYREXIA 20430 0.0598
275 APPENDICITIS 548 0.0597
276 BRONCHITIS 4385 0.0597
277 ARTHRITIS 4633 0.0596
278 TREATMENT FAILURE 4822 0.0595
279 HYPERSENSITIVITY 10888 0.0595
280 GENERALISED OEDEMA 723 0.0595
281 ENCEPHALOPATHY 1432 0.0592
282 HYPERTENSION 12380 0.0592
283 RENAL CYST 465 0.0592
284 MYASTHENIA GRAVIS 459 0.0591
285 DRY MOUTH 4718 0.0590
286 TRICUSPID VALVE INCOMPETENCE 458 0.0587
287 NERVE COMPRESSION 533 0.0586
288 INTERNATIONAL NORMALISED RATIO INCREASED 1664 0.0586
289 HEAD DISCOMFORT 1017 0.0585
290 VASCULITIS 673 0.0585
291 BLOOD TEST ABNORMAL 807 0.0582
292 BLOOD ALBUMIN DECREASED 453 0.0580
293 ROAD TRAFFIC ACCIDENT 2397 0.0580
294 POSTOPERATIVE WOUND INFECTION 386 0.0580
295 ALANINE AMINOTRANSFERASE INCREASED 3514 0.0580
296 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 961 0.0579
297 TRANSAMINASES INCREASED 1267 0.0578
298 BLOOD MAGNESIUM DECREASED 492 0.0577
299 FREQUENT BOWEL MOVEMENTS 1532 0.0577
300 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 4015 0.0575
301 PHARYNGITIS STREPTOCOCCAL 614 0.0575
302 MUSCULOSKELETAL CHEST PAIN 878 0.0574
303 ACUTE RESPIRATORY FAILURE 1085 0.0574
304 LOCALISED INFECTION 1371 0.0574
305 SARS-COV-2 TEST POSITIVE 756 0.0574
306 CONCUSSION 438 0.0573
307 HEART RATE INCREASED 5590 0.0572
308 POISONING 711 0.0571
309 BACTERAEMIA 662 0.0570
310 HEPATITIS CHOLESTATIC 336 0.0568
311 ARTHRALGIA 23147 0.0566
312 HYPOTHERMIA 566 0.0566
313 RIB FRACTURE 1145 0.0565
314 DYSPEPSIA 5457 0.0564
315 GANGRENE 336 0.0561
316 DRUG LEVEL INCREASED 916 0.0560
317 LYMPHOEDEMA 381 0.0560
318 SLEEP APNOEA SYNDROME 1056 0.0559
319 SEROTONIN SYNDROME 1055 0.0559
320 SINUS TACHYCARDIA 779 0.0557
321 PRODUCT PACKAGING ISSUE 509 0.0556
322 VITAMIN D DEFICIENCY 534 0.0555
323 WEIGHT INCREASED 12197 0.0555
324 DRUG USE DISORDER 453 0.0554
325 BLOOD IRON DECREASED 645 0.0554
326 POST-TRAUMATIC STRESS DISORDER 366 0.0552
327 RESPIRATORY TRACT CONGESTION 865 0.0551
328 TACHYCARDIA 4826 0.0550
329 THERAPY NON-RESPONDER 2417 0.0549
330 ARTERIOSCLEROSIS CORONARY ARTERY 356 0.0546
331 GASTROENTERITIS VIRAL 975 0.0546
332 ASPARTATE AMINOTRANSFERASE INCREASED 2858 0.0545
333 CARDIO-RESPIRATORY ARREST 2265 0.0545
334 CHILLS 6316 0.0545
335 CARDIOMEGALY 667 0.0545
336 RECTAL HAEMORRHAGE 2318 0.0545
337 OROPHARYNGEAL PAIN 4962 0.0543
338 PHARYNGITIS 666 0.0542
339 OCULAR DISCOMFORT 580 0.0541
340 PARAESTHESIA ORAL 767 0.0541
341 PRODUCT ADMINISTRATION INTERRUPTED 409 0.0540
342 RED BLOOD CELL COUNT DECREASED 1524 0.0539
343 HEPATIC STEATOSIS 989 0.0538
344 CHOLESTASIS 1014 0.0538
345 EYE INFECTION 592 0.0535
346 BLOOD ALKALINE PHOSPHATASE INCREASED 1310 0.0533
347 SMALL INTESTINAL OBSTRUCTION 646 0.0533
348 PHOTOPHOBIA 982 0.0533
349 HYPOTENSION 10506 0.0532
350 NASAL CONGESTION 3069 0.0531
351 ECCHYMOSIS 360 0.0531
352 COMA 2496 0.0531
353 COORDINATION ABNORMAL 735 0.0530
354 DECUBITUS ULCER 426 0.0530
355 APPETITE DISORDER 340 0.0529
356 MEDICATION ERROR 2897 0.0529
357 PROCTALGIA 335 0.0529
358 OROPHARYNGEAL DISCOMFORT 465 0.0527
359 ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS 402 0.0526
360 HIATUS HERNIA 673 0.0526
361 HYPOAESTHESIA 7774 0.0526
362 BACK PAIN 12029 0.0524
363 ACCIDENTAL OVERDOSE 1890 0.0524
364 IRON DEFICIENCY ANAEMIA 475 0.0524
365 UROSEPSIS 476 0.0523
366 BLOOD URINE PRESENT 983 0.0523
367 DYSPNOEA EXERTIONAL 1931 0.0521
368 BACTERIAL INFECTION 955 0.0521
369 KIDNEY INFECTION 1008 0.0521
370 GOUT 923 0.0521
371 HOSPICE CARE 506 0.0521
372 ABDOMINAL PAIN 11943 0.0521
373 HYPOALBUMINAEMIA 393 0.0521
374 TOOTHACHE 928 0.0520
375 PNEUMONIA 16578 0.0520
376 URINARY TRACT INFECTION 8722 0.0520
377 RHINORRHOEA 3305 0.0520
378 CARDIOGENIC SHOCK 731 0.0519
379 JOINT INJURY 1095 0.0519
380 RENAL INJURY 1535 0.0518
381 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 9021 0.0517
382 NEPHROPATHY 478 0.0516
383 DRUG HYPERSENSITIVITY 9882 0.0516
384 URTICARIA 8429 0.0513
385 CYST 628 0.0512
386 MALNUTRITION 561 0.0512
387 UPPER GASTROINTESTINAL HAEMORRHAGE 850 0.0510
388 MENTAL STATUS CHANGES 1400 0.0510
389 BLOOD UREA INCREASED 848 0.0510
390 PRODUCT LABEL ISSUE 337 0.0509
391 CELLULITIS 2531 0.0508
392 HYPERAESTHESIA 415 0.0508
393 RESPIRATORY SYNCYTIAL VIRUS INFECTION 433 0.0507
394 POOR QUALITY SLEEP 1070 0.0507
395 TACHYPNOEA 677 0.0507
396 POST PROCEDURAL INFECTION 405 0.0506
397 PRODUCT USE ISSUE 9328 0.0506
398 ARTERIAL OCCLUSIVE DISEASE 394 0.0505
399 BLOOD BILIRUBIN INCREASED 1350 0.0505
400 ABDOMINAL PAIN UPPER 10234 0.0505
401 SPINAL DISORDER 473 0.0505
402 PAIN IN JAW 1408 0.0503
403 OBSTRUCTIVE AIRWAYS DISORDER 554 0.0503
404 MUSCULAR WEAKNESS 5639 0.0503
405 PRESYNCOPE 1200 0.0503
406 TOOTH DISORDER 1106 0.0501
407 UNRESPONSIVE TO STIMULI 1272 0.0501
408 VIRAL INFECTION 1644 0.0501
409 DIVERTICULITIS 1366 0.0501
410 NEUTROPENIC SEPSIS 352 0.0498
411 COUGH 13690 0.0496
412 FULL BLOOD COUNT ABNORMAL 514 0.0494
413 HYPOKALAEMIA 2237 0.0494
414 COVID-19 8621 0.0494
415 DIVERTICULUM 350 0.0493
416 MITRAL VALVE INCOMPETENCE 550 0.0493
417 PULMONARY CONGESTION 643 0.0492
418 FLUID RETENTION 2469 0.0492
419 FACIAL PAIN 433 0.0492
420 BLOOD CREATININE INCREASED 3173 0.0491
421 EOSINOPHIL COUNT INCREASED 403 0.0491
422 LIMB INJURY 1313 0.0491
423 MOTOR DYSFUNCTION 490 0.0491
424 HEADACHE 30238 0.0489
425 NEPHROLITHIASIS 2209 0.0489
426 CONSTIPATION 10445 0.0489
427 NODULE 630 0.0489
428 TOOTH FRACTURE 532 0.0489
429 ANAL INCONTINENCE 429 0.0488
430 HYPERBILIRUBINAEMIA 496 0.0488
431 PAIN 29611 0.0488
432 PREGNANCY 973 0.0487
433 OVERDOSE 10412 0.0487
434 HYPERLIPIDAEMIA 575 0.0486
435 ARTHROPOD BITE 352 0.0485
436 PRODUCT ADMINISTRATION ERROR 954 0.0484
437 HAEMORRHOIDS 933 0.0484
438 FOETAL EXPOSURE DURING PREGNANCY 3875 0.0483
439 HYDRONEPHROSIS 356 0.0483
440 INCREASED TENDENCY TO BRUISE 439 0.0482
441 PYELONEPHRITIS 410 0.0482
442 ASCITES 1399 0.0482
443 HAEMOGLOBIN DECREASED 4893 0.0482
444 CLOSTRIDIUM DIFFICILE INFECTION 1027 0.0480
445 RENAL FAILURE 6339 0.0480
446 PHARYNGEAL SWELLING 453 0.0479
447 WHITE BLOOD CELL COUNT INCREASED 1814 0.0477
448 VOMITING 22036 0.0476
449 SEPSIS 5244 0.0476
450 INFLUENZA 5250 0.0476
451 ALOPECIA 9236 0.0476
452 PAIN IN EXTREMITY 13816 0.0474
453 BLOOD CALCIUM INCREASED 411 0.0474
454 FATIGUE 36342 0.0474
455 MUSCLE STRAIN 404 0.0474
456 PLEURAL EFFUSION 2845 0.0473
457 CHEST PAIN 8662 0.0473
458 OEDEMA PERIPHERAL 5707 0.0473
459 LOWER GASTROINTESTINAL HAEMORRHAGE 346 0.0472
460 SPINAL PAIN 545 0.0472
461 HAEMATEMESIS 1181 0.0471
462 MUSCULOSKELETAL DISCOMFORT 797 0.0469
463 HEMIPLEGIA 385 0.0467
464 DUODENAL ULCER 325 0.0467
465 GASTROINTESTINAL INFECTION 411 0.0466
466 COGNITIVE DISORDER 2141 0.0466
467 PELVIC FRACTURE 357 0.0466
468 HEPATOMEGALY 454 0.0466
469 WEIGHT DECREASED 12815 0.0465
470 HAEMOLYSIS 354 0.0464
471 CHOLELITHIASIS 1500 0.0463
472 HAEMODYNAMIC INSTABILITY 342 0.0462
473 ORAL PAIN 1024 0.0462
474 FEELING COLD 1270 0.0461
475 BLADDER DISORDER 452 0.0460
476 CONDITION AGGRAVATED 13709 0.0460
477 COLITIS 1708 0.0459
478 VITAMIN D DECREASED 388 0.0459
479 MOUTH ULCERATION 951 0.0458
480 CHEST DISCOMFORT 4609 0.0458
481 INTENTIONAL PRODUCT MISUSE 3916 0.0457
482 HYPERTHERMIA 341 0.0457
483 DENTAL CARIES 498 0.0457
484 BACK DISORDER 735 0.0456
485 FOOT FRACTURE 855 0.0456
486 LIVER FUNCTION TEST ABNORMAL 1315 0.0455
487 PNEUMONIA ASPIRATION 1120 0.0455
488 ATRIAL FLUTTER 360 0.0455
489 ASTHMA 5033 0.0455
490 BLOOD PRESSURE ABNORMAL 887 0.0454
491 SUBSTANCE ABUSE 365 0.0454
492 STRESS 3217 0.0453
493 ABSCESS 713 0.0453
494 CANDIDA INFECTION 746 0.0453
495 ADVERSE REACTION 592 0.0452
496 HYPONATRAEMIA 2507 0.0452
497 BLOOD SODIUM DECREASED 837 0.0451
498 ESCHERICHIA INFECTION 363 0.0450
499 PNEUMONIA BACTERIAL 405 0.0449
500 FEELING HOT 2720 0.0449
501 DECREASED APPETITE 10258 0.0449
502 MULTIPLE ORGAN DYSFUNCTION SYNDROME 1235 0.0448
503 ASTHENIA 16637 0.0448
504 SOMNOLENCE 8889 0.0448
505 EAR DISCOMFORT 452 0.0447
506 BODY HEIGHT DECREASED 477 0.0447
507 HERPES ZOSTER 2539 0.0447
508 ADRENAL INSUFFICIENCY 528 0.0447
509 BLOOD POTASSIUM INCREASED 715 0.0447
510 FISTULA 496 0.0446
511 PULMONARY OEDEMA 1971 0.0446
512 ASPHYXIA 359 0.0445
513 ANAPHYLACTIC REACTION 2410 0.0445
514 RASH MACULO-PAPULAR 970 0.0444
515 FALL 14551 0.0444
516 EATING DISORDER 935 0.0443
517 SKIN ULCER 1125 0.0442
518 PRODUCT DISTRIBUTION ISSUE 386 0.0441
519 GASTRIC ULCER 829 0.0441
520 PAROSMIA 327 0.0440
521 BLOOD PRESSURE DECREASED 2874 0.0439
522 TEMPERATURE INTOLERANCE 442 0.0439
523 BALANCE DISORDER 3746 0.0438
524 SPINAL COMPRESSION FRACTURE 363 0.0438
525 MASS 605 0.0437
526 MICTURITION URGENCY 489 0.0437
527 PLATELET COUNT INCREASED 563 0.0437
528 EMPHYSEMA 435 0.0436
529 GASTROENTERITIS 626 0.0435
530 PSEUDOMONAS INFECTION 363 0.0434
531 WRIST FRACTURE 514 0.0434
532 ROTATOR CUFF SYNDROME 552 0.0434
533 SPLENOMEGALY 501 0.0434
534 MIOSIS 340 0.0432
535 PALLOR 1164 0.0432
536 RASH 18481 0.0432
537 INTERVERTEBRAL DISC PROTRUSION 934 0.0432
538 BRAIN FOG 621 0.0431
539 STEVENS-JOHNSON SYNDROME 948 0.0431
540 DYSPNOEA 24049 0.0431
541 THROAT TIGHTNESS 1148 0.0431
542 URINE OUTPUT DECREASED 372 0.0430
543 PERIPHERAL COLDNESS 584 0.0429
544 ORAL HERPES 824 0.0429
545 HAEMATOCHEZIA 2332 0.0429
546 SCHIZOPHRENIA 514 0.0428
547 EPILEPSY 1287 0.0427
548 RESPIRATORY DISTRESS 1164 0.0427
549 APNOEA 330 0.0427
550 LUNG INFILTRATION 375 0.0426
551 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 2191 0.0426
552 BLOOD POTASSIUM DECREASED 1261 0.0425
553 CATARACT 2483 0.0424
554 RASH ERYTHEMATOUS 1961 0.0424
555 SNEEZING 936 0.0424
556 GLOMERULAR FILTRATION RATE DECREASED 507 0.0424
557 VENTRICULAR FIBRILLATION 465 0.0423
558 DIZZINESS POSTURAL 400 0.0422
559 RESTLESS LEGS SYNDROME 758 0.0422
560 PURPURA 368 0.0422
561 ALTERED STATE OF CONSCIOUSNESS 896 0.0421
562 PRODUCT USE IN UNAPPROVED INDICATION 10116 0.0420
563 HAEMOPTYSIS 1157 0.0419
564 OESOPHAGITIS 452 0.0419
565 DRUG LEVEL DECREASED 421 0.0417
566 ATRIAL SEPTAL DEFECT 346 0.0417
567 HERNIA 792 0.0417
568 SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION 665 0.0417
569 IMMUNOSUPPRESSION 355 0.0414
570 DISABILITY 808 0.0414
571 SINUS BRADYCARDIA 395 0.0413
572 ABDOMINAL DISTENSION 4237 0.0413
573 FACIAL PARALYSIS 345 0.0412
574 AMNESIA 2655 0.0412
575 AFFECT LABILITY 393 0.0412
576 TRANSFUSION 427 0.0411
577 GROIN PAIN 358 0.0411
578 THERAPEUTIC RESPONSE SHORTENED 1292 0.0411
579 INSOMNIA 10813 0.0411
580 PETECHIAE 421 0.0410
581 OSTEOMYELITIS 732 0.0410
582 ARTERIOSCLEROSIS 381 0.0410
583 PULMONARY HYPERTENSION 844 0.0409
584 HYPERHIDROSIS 5204 0.0409
585 GAMMA-GLUTAMYLTRANSFERASE INCREASED 895 0.0409
586 HYPOMAGNESAEMIA 559 0.0408
587 GAIT DISTURBANCE 7733 0.0408
588 TINNITUS 1851 0.0408
589 HEMIPARESIS 685 0.0407
590 OFF LABEL USE 34857 0.0407
591 ATRIAL FIBRILLATION 3917 0.0407
592 IMPAIRED GASTRIC EMPTYING 512 0.0407
593 DECREASED ACTIVITY 430 0.0407
594 SKIN LESION 1092 0.0406
595 DRY THROAT 407 0.0406
596 RENAL PAIN 423 0.0406
597 VAGINAL DISCHARGE 402 0.0406
598 CARPAL TUNNEL SYNDROME 561 0.0405
599 NAUSEA 31499 0.0405
600 PRURITUS 15079 0.0404
601 ECONOMIC PROBLEM 614 0.0404
602 DEHYDRATION 5312 0.0404
603 PNEUMONITIS 1076 0.0403
604 INTENTIONAL SELF-INJURY 803 0.0403
605 ILLNESS 3995 0.0403
606 LIMB DISCOMFORT 1229 0.0402
607 THERAPEUTIC RESPONSE UNEXPECTED 1787 0.0402
608 DIPLOPIA 1029 0.0401
609 GASTRITIS 1038 0.0400
610 HYPERCALCAEMIA 486 0.0399
611 BLOOD LACTATE DEHYDROGENASE INCREASED 628 0.0399
612 INCONTINENCE 417 0.0399
613 DRUG ADMINISTRATION ERROR 1222 0.0398
614 ACUTE RESPIRATORY DISTRESS SYNDROME 694 0.0397
615 ELECTROLYTE IMBALANCE 451 0.0397
616 IMPAIRED QUALITY OF LIFE 564 0.0397
617 HAEMATURIA 1344 0.0397
618 TUMOUR LYSIS SYNDROME 342 0.0397
619 ANAEMIA 7470 0.0397
620 RESPIRATORY ARREST 1088 0.0396
621 FAECES DISCOLOURED 848 0.0396
622 DYSURIA 1441 0.0396
623 BRADYCARDIA 2075 0.0396
624 SECRETION DISCHARGE 481 0.0394
625 APHONIA 543 0.0394
626 DIARRHOEA 25002 0.0394
627 HYPERSOMNIA 1109 0.0393
628 NEUTROPHIL COUNT DECREASED 1569 0.0392
629 EPISTAXIS 2891 0.0391
630 CHOLECYSTITIS 458 0.0390
631 LETHARGY 2216 0.0390
632 MYOCARDITIS 436 0.0390
633 THROMBOCYTOPENIA 4285 0.0389
634 SWOLLEN TONGUE 1196 0.0388
635 SUPRAVENTRICULAR TACHYCARDIA 366 0.0388
636 GALLBLADDER DISORDER 683 0.0386
637 LYMPHADENOPATHY 1351 0.0386
638 ANGIOEDEMA 1682 0.0386
639 URINARY INCONTINENCE 1126 0.0385
640 SUBARACHNOID HAEMORRHAGE 388 0.0385
641 INCORRECT DOSE ADMINISTERED 8538 0.0385
642 HYPOPHAGIA 963 0.0385
643 PARAESTHESIA 5985 0.0385
644 NIGHTMARE 1315 0.0383
645 MUSCLE RIGIDITY 451 0.0382
646 MUSCLE SPASMS 6919 0.0382
647 PERICARDIAL EFFUSION 867 0.0382
648 DYSPHAGIA 3560 0.0381
649 EOSINOPHILIA 657 0.0381
650 PLATELET COUNT DECREASED 4005 0.0381
651 MALAISE 16482 0.0380
652 JAUNDICE 1012 0.0380
653 RETCHING 797 0.0380
654 STAPHYLOCOCCAL INFECTION 1237 0.0379
655 COLITIS ULCERATIVE 1666 0.0379
656 RESPIRATORY FAILURE 2724 0.0378
657 SEPTIC SHOCK 1609 0.0377
658 PNEUMOTHORAX 590 0.0377
659 BASAL CELL CARCINOMA 581 0.0377
660 FULL BLOOD COUNT DECREASED 750 0.0377
661 HEAD INJURY 1172 0.0376
662 HALLUCINATION, VISUAL 778 0.0376
663 HAEMATOMA 963 0.0375
664 CYANOSIS 582 0.0374
665 BRONCHOSPASM 526 0.0372
666 FUNGAL INFECTION 1223 0.0372
667 DYSPHONIA 2141 0.0371
668 EYE PAIN 2022 0.0371
669 NEUROPATHY PERIPHERAL 3459 0.0371
670 HYPOKINESIA 531 0.0370
671 INFLUENZA LIKE ILLNESS 3014 0.0370
672 SHOCK 832 0.0369
673 HIP FRACTURE 1169 0.0369
674 PULMONARY THROMBOSIS 397 0.0368
675 HYPERKALAEMIA 1268 0.0368
676 POST PROCEDURAL COMPLICATION 699 0.0368
677 DYSSTASIA 1061 0.0367
678 WHITE BLOOD CELL COUNT DECREASED 3930 0.0367
679 DIZZINESS 18026 0.0367
680 BONE PAIN 2119 0.0366
681 DEVICE RELATED INFECTION 557 0.0366
682 GINGIVAL BLEEDING 493 0.0365
683 MEMORY IMPAIRMENT 4943 0.0364
684 FEEDING DISORDER 715 0.0363
685 RENAL FAILURE ACUTE 1541 0.0363
686 FLUSHING 3653 0.0363
687 ANKYLOSING SPONDYLITIS 466 0.0362
688 ANXIETY 10198 0.0362
689 PULMONARY EMBOLISM 3408 0.0362
690 TENDONITIS 555 0.0362
691 HEPATOCELLULAR INJURY 507 0.0361
692 CONJUNCTIVITIS 654 0.0361
693 ERYTHEMA MULTIFORME 330 0.0359
694 PANCREATITIS ACUTE 787 0.0357
695 UVEITIS 476 0.0357
696 RASH PRURITIC 1900 0.0357
697 HOT FLUSH 2654 0.0357
698 DRUG INTERACTION 5586 0.0357
699 MYDRIASIS 449 0.0355
700 FACE OEDEMA 592 0.0354
701 LACERATION 333 0.0354
702 BONE DISORDER 640 0.0353
703 DEPRESSION 7958 0.0353
704 DYSARTHRIA 1308 0.0352
705 SKIN HAEMORRHAGE 501 0.0352
706 GLAUCOMA 668 0.0351
707 SYNCOPE 3467 0.0351
708 LYMPHOPENIA 486 0.0350
709 APHASIA 1044 0.0349
710 HALLUCINATION 2577 0.0348
711 SPINAL FRACTURE 685 0.0348
712 ANGINA PECTORIS 988 0.0347
713 PANCYTOPENIA 1907 0.0347
714 URINARY RETENTION 1138 0.0347
715 MUCOSAL INFLAMMATION 891 0.0346
716 DEEP VEIN THROMBOSIS 2232 0.0346
717 LABORATORY TEST ABNORMAL 1005 0.0345
718 ANKLE FRACTURE 528 0.0345
719 NOCTURIA 412 0.0345
720 CARDIAC ARREST 2808 0.0343
721 PALPITATIONS 3962 0.0343
722 VERTIGO 2065 0.0343
723 MUSCLE TIGHTNESS 547 0.0343
724 DECREASED IMMUNE RESPONSIVENESS 330 0.0342
725 HYPOGLYCAEMIA 1631 0.0340
726 AGRANULOCYTOSIS 621 0.0340
727 SWELLING FACE 2181 0.0340
728 MYALGIA 5696 0.0340
729 BRAIN INJURY 336 0.0339
730 INITIAL INSOMNIA 341 0.0339
731 SCAR 571 0.0337
732 HYPOAESTHESIA ORAL 501 0.0337
733 SCAB 376 0.0336
734 PRODUCT USE COMPLAINT 512 0.0335
735 MUSCLE TWITCHING 761 0.0334
736 INTESTINAL OBSTRUCTION 1231 0.0333
737 BEDRIDDEN 431 0.0333
738 DRUG ABUSE 2741 0.0332
739 MELAENA 722 0.0332
740 THYROID DISORDER 504 0.0331
741 ILEUS 401 0.0330
742 OVARIAN CYST 326 0.0329
743 RESTLESSNESS 1188 0.0328
744 LEUKOPENIA 1611 0.0327
745 SCRATCH 334 0.0327
746 UPPER LIMB FRACTURE 645 0.0327
747 PROCEDURAL PAIN 891 0.0326
748 ERYTHEMA 6597 0.0326
749 CHOKING 623 0.0325
750 POLLAKIURIA 1334 0.0325
751 SUBDURAL HAEMATOMA 460 0.0325
752 MOVEMENT DISORDER 1032 0.0324
753 GASTROINTESTINAL HAEMORRHAGE 2680 0.0323
754 GASTROINTESTINAL PAIN 349 0.0323
755 PHOTOSENSITIVITY REACTION 524 0.0323
756 MIDDLE INSOMNIA 590 0.0321
757 PANCREATITIS 1677 0.0321
758 EJECTION FRACTION DECREASED 491 0.0320
759 VENTRICULAR EXTRASYSTOLES 328 0.0320
760 MULTI-ORGAN FAILURE 553 0.0319
761 DRY EYE 1526 0.0319
762 EXPIRED PRODUCT ADMINISTERED 1044 0.0319
763 AGITATION 2305 0.0317
764 INCORRECT PRODUCT ADMINISTRATION DURATION 635 0.0317
765 MYOCLONUS 373 0.0317
766 TREMOR 5198 0.0317
767 BLOOD COUNT ABNORMAL 479 0.0316
768 COLD SWEAT 549 0.0315
769 LIP SWELLING 1033 0.0315
770 CHROMATURIA 702 0.0315
771 MUSCLE ATROPHY 390 0.0314
772 HYPERGLYCAEMIA 1126 0.0314
773 MUSCULOSKELETAL DISORDER 593 0.0314
774 INTENTIONAL DRUG MISUSE 657 0.0314
775 EYE DISORDER 1011 0.0313
776 SKIN DISORDER 1025 0.0312
777 ANHEDONIA 813 0.0311
778 ADVERSE DRUG REACTION 2744 0.0311
779 SKIN DISCOLOURATION 1409 0.0311
780 ACCIDENT 365 0.0311
781 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 780 0.0309
782 PROTEINURIA 575 0.0309
783 IMPAIRED WORK ABILITY 654 0.0309
784 NEUTROPENIA 4127 0.0309
785 DISSEMINATED INTRAVASCULAR COAGULATION 430 0.0308
786 CARDIOMYOPATHY 450 0.0308
787 INTERNAL HAEMORRHAGE 348 0.0308
788 INJECTION SITE EXTRAVASATION 379 0.0308
789 RENAL DISORDER 1416 0.0307
790 THERAPY PARTIAL RESPONDER 456 0.0307
791 ADVERSE EVENT 2785 0.0306
792 FEELING JITTERY 577 0.0306
793 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 2175 0.0305
794 DEPRESSED MOOD 1585 0.0305
795 IMMUNE SYSTEM DISORDER 395 0.0304
796 INTENTIONAL DOSE OMISSION 820 0.0304
797 FLATULENCE 1696 0.0304
798 HYPOTHYROIDISM 954 0.0304
799 THROMBOSIS 2415 0.0303
800 DIABETES MELLITUS INADEQUATE CONTROL 530 0.0303
801 NEUROLEPTIC MALIGNANT SYNDROME 355 0.0302
802 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 1661 0.0302
803 RASH MACULAR 1036 0.0301
804 GASTRIC DISORDER 1034 0.0301
805 TRANSIENT ISCHAEMIC ATTACK 1006 0.0301
806 LACRIMATION INCREASED 887 0.0301
807 DISORIENTATION 1178 0.0301
808 PSYCHOTIC DISORDER 875 0.0300
809 ABDOMINAL PAIN LOWER 751 0.0300
810 VENTRICULAR TACHYCARDIA 489 0.0299
811 SKIN REACTION 415 0.0299
812 LOSS OF CONSCIOUSNESS 3749 0.0296
813 CORONARY ARTERY DISEASE 891 0.0296
814 DRUG ERUPTION 512 0.0294
815 ELECTROCARDIOGRAM QT PROLONGED 1045 0.0294
816 ATAXIA 345 0.0293
817 LACTIC ACIDOSIS 924 0.0292
818 THIRST 512 0.0291
819 HYPOCALCAEMIA 541 0.0290
820 RENAL IMPAIRMENT 2394 0.0290
821 DRUG INEFFECTIVE 37633 0.0290
822 RHABDOMYOLYSIS 1187 0.0289
823 QUALITY OF LIFE DECREASED 383 0.0289
824 DEMENTIA 792 0.0288
825 BURNING SENSATION 1992 0.0288
826 DELUSION 439 0.0287
827 DEVICE OCCLUSION 392 0.0286
828 FLUID OVERLOAD 416 0.0286
829 UNDERDOSE 2044 0.0283
830 SPEECH DISORDER 1465 0.0283
831 METASTASES TO BONE 455 0.0282
832 EYE SWELLING 1025 0.0281
833 ANAPHYLACTIC SHOCK 709 0.0280
834 SENSORY DISTURBANCE 446 0.0280
835 DYSGEUSIA 2059 0.0279
836 TENDON RUPTURE 339 0.0278
837 TOOTH EXTRACTION 341 0.0277
838 LUNG INFECTION 427 0.0275
839 HAIR COLOUR CHANGES 340 0.0274
840 BLOOD CREATINE PHOSPHOKINASE INCREASED 787 0.0273
841 INTERSTITIAL LUNG DISEASE 1294 0.0271
842 ACUTE MYOCARDIAL INFARCTION 793 0.0271
843 PULMONARY ARTERIAL HYPERTENSION 389 0.0271
844 SEIZURE 3064 0.0271
845 VISION BLURRED 3645 0.0270
846 RASH PAPULAR 596 0.0269
847 PARANOIA 459 0.0269
848 ORAL DISCOMFORT 368 0.0268
849 FEELING ABNORMAL 6337 0.0267
850 VISUAL IMPAIRMENT 3233 0.0266
851 DIABETES MELLITUS 2007 0.0266
852 SKIN FISSURES 494 0.0265
853 DRUG EFFECT INCOMPLETE 961 0.0264
854 DISEASE PROGRESSION 3043 0.0262
855 PRODUCT DOSE OMISSION IN ERROR 693 0.0261
856 THERAPEUTIC RESPONSE DECREASED 1551 0.0261
857 AGEUSIA 637 0.0258
858 ARRHYTHMIA 1211 0.0258
859 FEMUR FRACTURE 784 0.0256
860 SKIN CANCER 543 0.0255
861 CARDIAC FAILURE CONGESTIVE 2041 0.0255
862 PLASMA CELL MYELOMA 983 0.0255
863 DISEASE RECURRENCE 1194 0.0254
864 PRODUCT DOSE OMISSION ISSUE 7117 0.0253
865 DEAFNESS 654 0.0253
866 TOOTH LOSS 517 0.0251
867 DISTURBANCE IN ATTENTION 1336 0.0250
868 CRYING 900 0.0250
869 PARALYSIS 354 0.0250
870 GENERALISED TONIC-CLONIC SEIZURE 403 0.0250
871 HALLUCINATION, AUDITORY 391 0.0249
872 PANIC ATTACK 894 0.0248
873 HAEMORRHAGE INTRACRANIAL 367 0.0248
874 BLINDNESS 994 0.0247
875 INCREASED APPETITE 458 0.0247
876 NERVOUSNESS 1278 0.0247
877 DYSKINESIA 987 0.0247
878 PSYCHOMOTOR HYPERACTIVITY 403 0.0245
879 PREMATURE BABY 718 0.0241
880 HAEMORRHAGE 2454 0.0238
881 ECZEMA 1167 0.0235
882 BONE DENSITY DECREASED 733 0.0234
883 ISCHAEMIC STROKE 413 0.0234
884 BLOOD TRIGLYCERIDES INCREASED 408 0.0233
885 EXTRA DOSE ADMINISTERED 915 0.0232
886 TREATMENT NONCOMPLIANCE 1245 0.0232
887 CEREBRAL HAEMORRHAGE 814 0.0231
888 MULTIPLE FRACTURES 377 0.0230
889 HEPATIC FUNCTION ABNORMAL 842 0.0230
890 CARDIAC FAILURE 1824 0.0230
891 MENTAL DISORDER 981 0.0228
892 CARDIAC DISORDER 2113 0.0228
893 EYE PRURITUS 739 0.0227
894 METASTASES TO LIVER 393 0.0227
895 PRODUCT PRESCRIBING ERROR 530 0.0227
896 HYPOACUSIS 951 0.0224
897 MENTAL IMPAIRMENT 537 0.0224
898 THINKING ABNORMAL 414 0.0224
899 ERUCTATION 420 0.0224
900 LYMPHOMA 340 0.0222
901 CIRCULATORY COLLAPSE 372 0.0220
902 MULTIPLE SCLEROSIS 1041 0.0219
903 FRACTURE 409 0.0219
904 CYTOMEGALOVIRUS INFECTION 358 0.0218
905 PRODUCT AVAILABILITY ISSUE 481 0.0217
906 PREMATURE DELIVERY 340 0.0215
907 OCULAR HYPERAEMIA 981 0.0213
908 CEREBROVASCULAR ACCIDENT 3569 0.0213
909 FEAR 568 0.0212
910 PSORIASIS 2698 0.0209
911 NEOPLASM PROGRESSION 715 0.0206
912 SUICIDAL IDEATION 1863 0.0206
913 UNEVALUABLE EVENT 1508 0.0202
914 SKIN EXFOLIATION 1656 0.0202
915 INCORRECT DRUG ADMINISTRATION DURATION 567 0.0201
916 NERVOUS SYSTEM DISORDER 621 0.0201
917 MALIGNANT NEOPLASM PROGRESSION 2017 0.0201
918 DERMATITIS 409 0.0200
919 SURGERY 1139 0.0199
920 PRURITUS GENERALISED 431 0.0199
921 ABNORMAL BEHAVIOUR 776 0.0197
922 AGGRESSION 968 0.0196
923 PELVIC PAIN 350 0.0195
924 IRRITABILITY 1158 0.0195
925 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 447 0.0194
926 INJECTION SITE REACTION 1303 0.0192
927 PAIN OF SKIN 512 0.0192
928 PRODUCT PHYSICAL ISSUE 377 0.0192
929 HOSPITALISATION 2863 0.0190
930 MULTIPLE SCLEROSIS RELAPSE 1295 0.0190
931 THERAPY INTERRUPTED 1288 0.0189
932 LOCAL SWELLING 330 0.0189
933 DEATH 15715 0.0185
934 MOOD SWINGS 581 0.0185
935 RASH GENERALISED 477 0.0184
936 MOOD ALTERED 492 0.0183
937 DRY SKIN 2359 0.0182
938 ANGER 607 0.0181
939 ACTIVITIES OF DAILY LIVING IMPAIRED 352 0.0178
940 EMOTIONAL DISTRESS 2127 0.0177
941 OSTEONECROSIS OF JAW 430 0.0175
942 ABASIA 432 0.0175
943 BONE MARROW FAILURE 350 0.0173
944 PRODUCT PRESCRIBING ISSUE 346 0.0172
945 PERITONITIS 350 0.0171
946 EYE IRRITATION 939 0.0171
947 MYOCARDIAL INFARCTION 2956 0.0170
948 EMOTIONAL DISORDER 519 0.0170
949 THERAPY CESSATION 853 0.0169
950 CONVULSION 950 0.0166
951 BLOOD GLUCOSE DECREASED 759 0.0160
952 NEEDLE ISSUE 447 0.0158
953 ABNORMAL DREAMS 430 0.0157
954 CEREBRAL INFARCTION 377 0.0156
955 PRODUCT QUALITY ISSUE 2077 0.0156
956 NEOPLASM MALIGNANT 1022 0.0155
957 LUNG NEOPLASM MALIGNANT 629 0.0154
958 ACNE 1159 0.0154
959 BLOOD GLUCOSE INCREASED 2789 0.0149
960 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 2964 0.0149
961 OSTEONECROSIS 485 0.0148
962 DRUG EXPOSURE DURING PREGNANCY 493 0.0145
963 WITHDRAWAL SYNDROME 600 0.0144
964 DIABETIC KETOACIDOSIS 335 0.0142
965 VAGINAL HAEMORRHAGE 591 0.0141
966 CARDIOVASCULAR DISORDER 355 0.0141
967 GLYCOSYLATED HAEMOGLOBIN INCREASED 349 0.0140
968 ABORTION SPONTANEOUS 549 0.0138
969 PRODUCT DOSE OMISSION 891 0.0136
970 DRUG EFFECTIVE FOR UNAPPROVED INDICATION 390 0.0135
971 INJECTION SITE BRUISING 1035 0.0133
972 INJECTION SITE PRURITUS 843 0.0128
973 INJECTION SITE RASH 376 0.0126
974 INJECTION SITE ERYTHEMA 1528 0.0125
975 DRUG EFFECT DECREASED 672 0.0125
976 VISUAL ACUITY REDUCED 410 0.0124
977 DEVICE DISLOCATION 527 0.0123
978 INJECTION SITE MASS 443 0.0122
979 INJECTION SITE SWELLING 894 0.0120
980 SKIN IRRITATION 513 0.0113
981 DEVICE ISSUE 915 0.0106
982 PRODUCT SUBSTITUTION ISSUE 597 0.0105
983 DRUG DEPENDENCE 1667 0.0104
984 INJECTION SITE PAIN 3104 0.0104
985 INJECTION SITE HAEMORRHAGE 750 0.0096
986 ACCIDENTAL EXPOSURE TO PRODUCT 884 0.0090
987 BREAST CANCER 826 0.0089
988 DRUG DOSE OMISSION 1441 0.0087
989 SKIN BURNING SENSATION 600 0.0085
990 DEVICE MALFUNCTION 555 0.0084
991 DEVICE LEAKAGE 330 0.0079
992 DRUG WITHDRAWAL SYNDROME 689 0.0079
993 NO ADVERSE EVENT 1370 0.0078
994 DERMATITIS ATOPIC 378 0.0077
995 PROSTATE CANCER 411 0.0051
996 PRODUCT STORAGE ERROR 408 0.0048