Drug Side Effects

ASPIRIN 325 MG

ASPIRIN 325 MG was reported 415616 times

ASPIRIN 325 MG is most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 CHRONIC KIDNEY DISEASE-MINERAL AND BONE DISORDER 333 0.3310
1 NEPHROGENIC ANAEMIA 1376 0.3134
2 HYPERPARATHYROIDISM SECONDARY 725 0.3113
3 HAEMORRHAGIC ARTERIOVENOUS MALFORMATION 265 0.2909
4 VASCULAR STENT THROMBOSIS 422 0.2481
5 SYSTEMIC INFECTION 321 0.2178
6 CORONARY ARTERY STENOSIS 916 0.2069
7 ANGINA UNSTABLE 1251 0.2061
8 THROMBOSIS IN DEVICE 625 0.1997
9 CAROTID ARTERY STENOSIS 615 0.1988
10 HAEMORRHAGIC ANAEMIA 849 0.1926
11 AORTIC VALVE STENOSIS 280 0.1874
12 REBOUND ACID HYPERSECRETION 558 0.1866
13 ISCHAEMIC CARDIOMYOPATHY 537 0.1860
14 CORONARY ARTERY DISEASE 5188 0.1850
15 DIVERTICULUM INTESTINAL HAEMORRHAGIC 367 0.1831
16 CORONARY ARTERIAL STENT INSERTION 800 0.1817
17 DIASTOLIC DYSFUNCTION 463 0.1806
18 LOWER GASTROINTESTINAL HAEMORRHAGE 1174 0.1767
19 CORONARY ARTERY OCCLUSION 2092 0.1710
20 UPPER GASTROINTESTINAL HAEMORRHAGE 2436 0.1685
21 CORONARY ARTERY THROMBOSIS 305 0.1684
22 RETROPERITONEAL HAEMORRHAGE 365 0.1611
23 ACUTE MYOCARDIAL INFARCTION 4075 0.1586
24 OCCULT BLOOD POSITIVE 295 0.1577
25 GASTROINTESTINAL HAEMORRHAGE 11469 0.1536
26 ESSENTIAL HYPERTENSION 327 0.1527
27 CORONARY ARTERY BYPASS 756 0.1473
28 MITRAL VALVE INCOMPETENCE 1390 0.1469
29 LABELLED DRUG-DRUG INTERACTION MEDICATION ERROR 1183 0.1464
30 DUODENAL ULCER HAEMORRHAGE 367 0.1447
31 ARTERIOSCLEROSIS CORONARY ARTERY 785 0.1446
32 VENTRICULAR HYPERTROPHY 335 0.1436
33 END STAGE RENAL DISEASE 2388 0.1434
34 AORTIC STENOSIS 410 0.1420
35 CAROTID ARTERY OCCLUSION 443 0.1414
36 ORTHOPNOEA 390 0.1388
37 TRICUSPID VALVE INCOMPETENCE 866 0.1382
38 ULCER HAEMORRHAGE 763 0.1375
39 LEFT VENTRICULAR HYPERTROPHY 500 0.1369
40 LACUNAR INFARCTION 287 0.1355
41 VENTRICULAR DYSFUNCTION 270 0.1337
42 GASTRIC ULCER HAEMORRHAGE 666 0.1335
43 BRAIN NATRIURETIC PEPTIDE INCREASED 324 0.1334
44 THERAPEUTIC AGENT TOXICITY 445 0.1333
45 AORTIC ARTERIOSCLEROSIS 279 0.1314
46 AORTIC VALVE INCOMPETENCE 457 0.1280
47 DUODENAL ULCER 748 0.1276
48 MULTIPLE INJURIES 779 0.1273
49 HYPERLIPIDAEMIA 1321 0.1268
50 MYOCARDIAL ISCHAEMIA 1303 0.1256
51 BUNDLE BRANCH BLOCK LEFT 469 0.1255
52 FLUSHING 11120 0.1255
53 VENTRICULAR HYPOKINESIA 339 0.1240
54 HIGH DENSITY LIPOPROTEIN DECREASED 358 0.1235
55 ANGINA PECTORIS 3083 0.1225
56 RENAL FAILURE CHRONIC 941 0.1223
57 LEFT VENTRICULAR FAILURE 344 0.1216
58 PERIPHERAL VASCULAR DISORDER 569 0.1213
59 GASTRITIS EROSIVE 492 0.1209
60 PERIPHERAL ARTERIAL OCCLUSIVE DISEASE 413 0.1209
61 DUODENITIS 306 0.1196
62 BENIGN PROSTATIC HYPERPLASIA 528 0.1190
63 NON-CARDIAC CHEST PAIN 339 0.1167
64 CREATININE RENAL CLEARANCE DECREASED 414 0.1152
65 ACUTE CORONARY SYNDROME 831 0.1143
66 DIVERTICULUM 758 0.1124
67 ARTERIOSCLEROSIS 903 0.1123
68 HAEMORRHAGIC STROKE 746 0.1117
69 ARTERIAL OCCLUSIVE DISEASE 751 0.1110
70 MELAENA 2050 0.1089
71 DIABETIC NEUROPATHY 480 0.1088
72 HAEMORRHAGE INTRACRANIAL 1384 0.1044
73 ATRIOVENTRICULAR BLOCK FIRST DEGREE 404 0.1043
74 GASTRIC HAEMORRHAGE 1068 0.1038
75 TROPONIN INCREASED 573 0.1035
76 SUPRAVENTRICULAR EXTRASYSTOLES 301 0.1034
77 TRANSIENT ISCHAEMIC ATTACK 3002 0.1029
78 CHRONIC KIDNEY DISEASE 7130 0.1027
79 ATRIAL FLUTTER 694 0.1015
80 PEPTIC ULCER 285 0.1001
81 STENT PLACEMENT 687 0.0998
82 CARDIAC FAILURE CONGESTIVE 7414 0.0996
83 LEFT VENTRICULAR DYSFUNCTION 534 0.0989
84 BREATH SOUNDS ABNORMAL 373 0.0984
85 HYPERCHOLESTEROLAEMIA 658 0.0983
86 DYSLIPIDAEMIA 402 0.0980
87 ATELECTASIS 812 0.0979
88 RENAL FAILURE ACUTE 4141 0.0975
89 ECCHYMOSIS 570 0.0969
90 ELECTROCARDIOGRAM ST SEGMENT ELEVATION 279 0.0969
91 VENTRICULAR EXTRASYSTOLES 860 0.0967
92 IRON DEFICIENCY ANAEMIA 715 0.0963
93 BUNDLE BRANCH BLOCK RIGHT 384 0.0958
94 CARDIOMEGALY 1053 0.0945
95 HYPOVOLAEMIA 458 0.0943
96 SUBDURAL HAEMATOMA 1151 0.0933
97 CARDIAC MURMUR 717 0.0930
98 SHOCK HAEMORRHAGIC 587 0.0927
99 THROMBOTIC THROMBOCYTOPENIC PURPURA 284 0.0917
100 SPINAL OSTEOARTHRITIS 684 0.0917
101 VENTRICULAR TACHYCARDIA 1256 0.0917
102 BLOOD UREA INCREASED 1343 0.0910
103 RALES 441 0.0906
104 GASTRIC ULCER 1459 0.0902
105 DIVERTICULUM INTESTINAL 305 0.0902
106 ELECTROCARDIOGRAM ABNORMAL 608 0.0898
107 SUBARACHNOID HAEMORRHAGE 764 0.0897
108 HAEMORRHOIDAL HAEMORRHAGE 378 0.0890
109 HAEMATOCRIT DECREASED 1550 0.0889
110 SINUS BRADYCARDIA 717 0.0886
111 HAEMATURIA 2609 0.0885
112 CEREBRAL ATROPHY 300 0.0878
113 VENTRICULAR FIBRILLATION 821 0.0873
114 CARDIAC FAILURE CHRONIC 288 0.0865
115 CEREBRAL HAEMORRHAGE 2579 0.0863
116 RENAL CYST 584 0.0861
117 ATRIAL FIBRILLATION 6874 0.0860
118 SPINAL COLUMN STENOSIS 406 0.0856
119 BLOOD PRESSURE DIASTOLIC DECREASED 519 0.0854
120 RECTAL HAEMORRHAGE 3091 0.0853
121 CATHETERISATION CARDIAC 320 0.0840
122 NOCTURIA 780 0.0838
123 MYOCARDIAL INFARCTION 13248 0.0832
124 RHINITIS ALLERGIC 288 0.0832
125 ISCHAEMIA 336 0.0832
126 ORTHOSTATIC HYPOTENSION 1207 0.0832
127 HAEMATEMESIS 1786 0.0831
128 HAEMATOMA 1864 0.0830
129 INTERNAL HAEMORRHAGE 791 0.0826
130 HIATUS HERNIA 920 0.0826
131 CEREBRAL ISCHAEMIA 380 0.0825
132 GOUT 1199 0.0824
133 DYSPNOEA EXERTIONAL 2387 0.0823
134 INTERNATIONAL NORMALISED RATIO DECREASED 319 0.0818
135 INCREASED TENDENCY TO BRUISE 638 0.0799
136 ATRIOVENTRICULAR BLOCK COMPLETE 434 0.0799
137 FULL BLOOD COUNT ABNORMAL 553 0.0798
138 CARDIAC VALVE DISEASE 393 0.0797
139 PERIPHERAL ISCHAEMIA 271 0.0796
140 HEPARIN-INDUCED THROMBOCYTOPENIA 331 0.0790
141 PROTHROMBIN TIME PROLONGED 437 0.0789
142 ANGIOPATHY 381 0.0786
143 COAGULOPATHY 1117 0.0784
144 SLEEP APNOEA SYNDROME 1278 0.0780
145 CARDIOGENIC SHOCK 828 0.0776
146 DIFFICULTY IN WALKING 267 0.0775
147 ATRIOVENTRICULAR BLOCK 496 0.0773
148 BLOOD PRESSURE SYSTOLIC INCREASED 1206 0.0766
149 SUPRAVENTRICULAR TACHYCARDIA 613 0.0761
150 HEMIPLEGIA 539 0.0757
151 EJECTION FRACTION DECREASED 961 0.0755
152 BLOOD CALCIUM DECREASED 716 0.0752
153 BODY HEIGHT DECREASED 734 0.0749
154 RENAL TUBULAR NECROSIS 592 0.0746
155 FAECES DISCOLOURED 1352 0.0745
156 HYPERKALAEMIA 2104 0.0744
157 INTERVERTEBRAL DISC DEGENERATION 609 0.0742
158 RENAL INJURY 2083 0.0742
159 AORTIC ANEURYSM 491 0.0741
160 ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED 330 0.0740
161 GASTRITIS 1616 0.0739
162 RHABDOMYOLYSIS 2521 0.0738
163 MYOPATHY 523 0.0736
164 ACUTE KIDNEY INJURY 8621 0.0736
165 FEELING HOT 3772 0.0735
166 INTERNATIONAL NORMALISED RATIO INCREASED 1981 0.0735
167 HYPOVOLAEMIC SHOCK 282 0.0733
168 CARDIAC TAMPONADE 284 0.0732
169 LOW DENSITY LIPOPROTEIN INCREASED 433 0.0730
170 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 3128 0.0726
171 CARDIOMYOPATHY 902 0.0724
172 SQUAMOUS CELL CARCINOMA OF SKIN 331 0.0723
173 UROSEPSIS 535 0.0722
174 ANEURYSM 297 0.0715
175 HAEMOPTYSIS 1671 0.0714
176 ACUTE RESPIRATORY FAILURE 1046 0.0710
177 RENAL FAILURE 8350 0.0708
178 EXERCISE TOLERANCE DECREASED 325 0.0707
179 MULTIPLE MYELOMA 328 0.0704
180 FULL BLOOD COUNT DECREASED 1089 0.0702
181 POST PROCEDURAL HAEMORRHAGE 697 0.0700
182 CARDIAC FAILURE ACUTE 353 0.0700
183 EPISTAXIS 4329 0.0697
184 ISCHAEMIC STROKE 1041 0.0695
185 BRONCHIECTASIS 342 0.0693
186 OESOPHAGITIS 618 0.0692
187 HEMIPARESIS 1014 0.0690
188 BLOOD POTASSIUM INCREASED 928 0.0687
189 BLOOD URIC ACID INCREASED 309 0.0684
190 HYPOMAGNESAEMIA 727 0.0684
191 PULMONARY ALVEOLAR HAEMORRHAGE 280 0.0683
192 HAEMOGLOBIN DECREASED 5847 0.0681
193 CONGESTIVE CARDIOMYOPATHY 288 0.0680
194 EXOSTOSIS 492 0.0679
195 COLITIS ISCHAEMIC 369 0.0675
196 HEART RATE IRREGULAR 1331 0.0670
197 MACULAR DEGENERATION 631 0.0669
198 CARDIAC PACEMAKER INSERTION 335 0.0668
199 OBSTRUCTIVE AIRWAYS DISORDER 601 0.0662
200 TUBULOINTERSTITIAL NEPHRITIS 991 0.0662
201 BLOOD MAGNESIUM DECREASED 443 0.0656
202 GLOMERULAR FILTRATION RATE DECREASED 557 0.0654
203 PULMONARY HYPERTENSION 1156 0.0652
204 CHEST PAIN 10145 0.0649
205 BURSITIS 540 0.0648
206 BLOOD SODIUM DECREASED 992 0.0644
207 MYOSITIS 430 0.0643
208 HUMERUS FRACTURE 262 0.0641
209 BRADYCARDIA 2884 0.0640
210 GASTROOESOPHAGEAL REFLUX DISEASE 4098 0.0640
211 DIZZINESS POSTURAL 450 0.0638
212 ELECTROLYTE IMBALANCE 575 0.0638
213 CEREBRAL INFARCTION 1308 0.0635
214 PULSE ABSENT 261 0.0634
215 CONTUSION 4912 0.0632
216 CEREBROVASCULAR ACCIDENT 9236 0.0632
217 FAILURE TO THRIVE 283 0.0630
218 BLOOD CREATININE INCREASED 3463 0.0630
219 HAEMATOCHEZIA 2695 0.0629
220 MULTIPLE ALLERGIES 375 0.0626
221 OEDEMA PERIPHERAL 6648 0.0624
222 PULMONARY CONGESTION 659 0.0624
223 ANAEMIA 9870 0.0624
224 LUNG INFILTRATION 504 0.0624
225 FAECALOMA 262 0.0620
226 PLATELET COUNT INCREASED 654 0.0619
227 MOUTH HAEMORRHAGE 363 0.0619
228 NEPHROPATHY 503 0.0618
229 OSTEOARTHRITIS 2092 0.0618
230 SYNCOPE 5118 0.0613
231 MENTAL STATUS CHANGES 1422 0.0612
232 BLOOD CREATINE PHOSPHOKINASE INCREASED 1560 0.0609
233 GLUCOSE TOLERANCE IMPAIRED 281 0.0609
234 INTESTINAL ISCHAEMIA 271 0.0608
235 VITAMIN D DEFICIENCY 478 0.0607
236 BLOOD PRESSURE INADEQUATELY CONTROLLED 338 0.0604
237 POLYP 325 0.0603
238 BLOOD CHOLESTEROL INCREASED 2241 0.0599
239 EXTRASYSTOLES 364 0.0598
240 GROIN PAIN 444 0.0598
241 HEART RATE DECREASED 1760 0.0598
242 ABNORMAL LOSS OF WEIGHT 327 0.0596
243 BLOOD TRIGLYCERIDES INCREASED 893 0.0592
244 BLOOD IRON DECREASED 514 0.0590
245 BLOOD URINE PRESENT 948 0.0588
246 PERICARDIAL EFFUSION 1071 0.0586
247 ECONOMIC PROBLEM 865 0.0583
248 ROTATOR CUFF SYNDROME 634 0.0583
249 PULMONARY OEDEMA 2162 0.0582
250 URINE OUTPUT DECREASED 437 0.0582
251 STOMACH DISCOMFORT 300 0.0580
252 BLOOD POTASSIUM DECREASED 1441 0.0580
253 FLANK PAIN 448 0.0580
254 LEUKOCYTOSIS 846 0.0579
255 HAEMODIALYSIS 471 0.0579
256 DIABETES MELLITUS INADEQUATE CONTROL 853 0.0577
257 MICTURITION URGENCY 526 0.0576
258 GINGIVAL BLEEDING 601 0.0576
259 RED BLOOD CELL COUNT DECREASED 1337 0.0575
260 LACERATION 539 0.0572
261 HAEMORRHAGE 4758 0.0571
262 MUSCULOSKELETAL CHEST PAIN 720 0.0571
263 HYPONATRAEMIA 2659 0.0570
264 TYPE 2 DIABETES MELLITUS 1549 0.0569
265 CHOLECYSTITIS ACUTE 270 0.0568
266 CIRCULATORY COLLAPSE 836 0.0566
267 HYPOGLYCAEMIA 2312 0.0566
268 OBESITY 683 0.0565
269 BASAL CELL CARCINOMA 712 0.0565
270 BLOOD ALBUMIN DECREASED 372 0.0563
271 PERIPHERAL COLDNESS 641 0.0561
272 URINE ODOUR ABNORMAL 279 0.0561
273 HYPOTENSION 9200 0.0561
274 CATARACT 2556 0.0560
275 HAEMORRHOIDS 909 0.0559
276 PROSTATIC SPECIFIC ANTIGEN INCREASED 633 0.0558
277 EYE HAEMORRHAGE 631 0.0556
278 PRESYNCOPE 1080 0.0556
279 ULCER 730 0.0555
280 EMPHYSEMA 478 0.0553
281 SEASONAL ALLERGY 556 0.0552
282 DIVERTICULITIS 1224 0.0550
283 SKIN LACERATION 427 0.0549
284 ANOREXIA 705 0.0547
285 CARDIAC FAILURE 3583 0.0546
286 GANGRENE 288 0.0544
287 RIB FRACTURE 912 0.0544
288 CARDIAC FLUTTER 287 0.0543
289 CARDIAC OPERATION 355 0.0543
290 FAECAL INCONTINENCE 261 0.0542
291 VISUAL DISTURBANCE 311 0.0541
292 PLEURAL EFFUSION 2737 0.0541
293 PULMONARY HAEMORRHAGE 367 0.0541
294 FALL 14648 0.0540
295 DEHYDRATION 5991 0.0539
296 SKIN ULCER 1149 0.0538
297 NEUROPATHY PERIPHERAL 3856 0.0534
298 CARPAL TUNNEL SYNDROME 615 0.0534
299 GENERALISED ERYTHEMA 304 0.0533
300 HYPOPHAGIA 1056 0.0530
301 UNRESPONSIVE TO STIMULI 1110 0.0529
302 PRODUCTIVE COUGH 1872 0.0528
303 WALKING AID USER 266 0.0528
304 MUSCULOSKELETAL DISCOMFORT 736 0.0528
305 BLOOD PRESSURE FLUCTUATION 1082 0.0528
306 HYPERGLYCAEMIA 1598 0.0527
307 HYPERCALCAEMIA 528 0.0527
308 MULTI-ORGAN FAILURE 913 0.0526
309 MUSCLE STRAIN 377 0.0526
310 SCIATICA 605 0.0525
311 DECUBITUS ULCER 361 0.0525
312 SPINAL COMPRESSION FRACTURE 394 0.0524
313 POSTOPERATIVE WOUND INFECTION 280 0.0523
314 DYSURIA 1616 0.0523
315 BLOOD ALKALINE PHOSPHATASE INCREASED 1133 0.0523
316 RESPIRATORY RATE INCREASED 377 0.0523
317 INGUINAL HERNIA 265 0.0523
318 HYPOKALAEMIA 1919 0.0522
319 ACIDOSIS 334 0.0522
320 TENDERNESS 460 0.0522
321 SENSORY LOSS 351 0.0519
322 ERUCTATION 692 0.0519
323 MENISCUS INJURY 261 0.0516
324 PETECHIAE 443 0.0515
325 GASTROENTERITIS 611 0.0515
326 PLASMA CELL MYELOMA 1612 0.0515
327 BLOOD PRESSURE DECREASED 2795 0.0514
328 BLOOD CALCIUM INCREASED 375 0.0514
329 MUSCULAR WEAKNESS 4777 0.0514
330 PULMONARY MASS 596 0.0514
331 REFUSAL OF TREATMENT BY PATIENT 279 0.0512
332 DYSARTHRIA 1610 0.0512
333 VASCULITIS 477 0.0511
334 HYPOXIA 1421 0.0511
335 LARGE INTESTINE POLYP 291 0.0510
336 POST PROCEDURAL COMPLICATION 822 0.0508
337 CLOSTRIDIUM DIFFICILE COLITIS 433 0.0507
338 CONSTIPATION 8429 0.0507
339 BALANCE DISORDER 3655 0.0504
340 THROMBOSIS 3399 0.0504
341 GASTROINTESTINAL PAIN 428 0.0504
342 HYPERTENSION 8637 0.0503
343 SKIN HAEMORRHAGE 478 0.0503
344 TACHYPNOEA 533 0.0502
345 RENAL IMPAIRMENT 3315 0.0501
346 VITAMIN D DECREASED 359 0.0500
347 PHARYNGOLARYNGEAL PAIN 266 0.0500
348 CELLULITIS 2117 0.0500
349 COORDINATION ABNORMAL 622 0.0500
350 RETINAL HAEMORRHAGE 293 0.0499
351 POLYURIA 335 0.0499
352 OSTEOPENIA 653 0.0499
353 LOW BIRTH WEIGHT BABY 319 0.0497
354 RHINITIS 320 0.0496
355 INCONTINENCE 436 0.0496
356 HEAD INJURY 1250 0.0493
357 LIVER FUNCTION TEST ABNORMAL 1295 0.0493
358 POLLAKIURIA 1671 0.0491
359 RED BLOOD CELL SEDIMENTATION RATE INCREASED 439 0.0490
360 SINUS DISORDER 786 0.0489
361 FLUID OVERLOAD 713 0.0488
362 OEDEMA 2099 0.0487
363 DRUG INTERACTION 6394 0.0487
364 CHROMATURIA 927 0.0486
365 ASTHENIA 14825 0.0485
366 MIDDLE INSOMNIA 707 0.0485
367 CHOLELITHIASIS 1322 0.0485
368 URINARY TRACT INFECTION 6498 0.0484
369 SWOLLEN TONGUE 1281 0.0484
370 BODY TEMPERATURE DECREASED 412 0.0482
371 BLOOD PRESSURE INCREASED 6045 0.0481
372 WHEEZING 2114 0.0481
373 HIP FRACTURE 1241 0.0481
374 WHITE BLOOD CELL COUNT INCREASED 1566 0.0480
375 PANCREATITIS ACUTE 852 0.0480
376 PNEUMONIA 12190 0.0479
377 INFARCTION 300 0.0479
378 HEPATIC STEATOSIS 715 0.0478
379 NERVE COMPRESSION 357 0.0478
380 LIMB INJURY 1006 0.0478
381 BRONCHITIS 3001 0.0477
382 URINARY INCONTINENCE 1168 0.0476
383 APHASIA 1208 0.0476
384 WOUND INFECTION 347 0.0476
385 DEEP VEIN THROMBOSIS 2748 0.0475
386 DEMENTIA 996 0.0475
387 SINUS TACHYCARDIA 560 0.0474
388 HICCUPS 307 0.0474
389 DYSPEPSIA 3717 0.0473
390 CHEST DISCOMFORT 3835 0.0473
391 LOCALISED INFECTION 926 0.0471
392 SPLENOMEGALY 460 0.0470
393 BLOOD PRESSURE ABNORMAL 708 0.0470
394 MUSCULOSKELETAL PAIN 2250 0.0470
395 PARAESTHESIA 6270 0.0470
396 RESPIRATORY FAILURE 2835 0.0469
397 CARDIAC DISORDER 3712 0.0468
398 MYALGIA 6490 0.0465
399 HOSPICE CARE 338 0.0465
400 CONFUSIONAL STATE 6236 0.0464
401 AGEUSIA 953 0.0464
402 DYSPNOEA 21334 0.0463
403 SQUAMOUS CELL CARCINOMA 355 0.0463
404 INTERVERTEBRAL DISC PROTRUSION 863 0.0463
405 BACK DISORDER 621 0.0463
406 ARRHYTHMIA 1873 0.0463
407 ATAXIA 466 0.0461
408 SMALL INTESTINAL OBSTRUCTION 449 0.0461
409 HAEMODYNAMIC INSTABILITY 261 0.0459
410 CYSTITIS 1239 0.0457
411 BONE DISORDER 740 0.0455
412 PULMONARY FIBROSIS 654 0.0455
413 HYPOCALCAEMIA 681 0.0454
414 ANGIOEDEMA 1622 0.0454
415 DIABETES MELLITUS 2962 0.0453
416 RIGHT VENTRICULAR FAILURE 281 0.0453
417 PHARYNGITIS 473 0.0453
418 JOINT INJURY 784 0.0452
419 MUSCLE ATROPHY 429 0.0452
420 LIPASE INCREASED 287 0.0452
421 HYDRONEPHROSIS 277 0.0452
422 HYPOKINESIA 554 0.0451
423 BLOOD GLUCOSE FLUCTUATION 422 0.0451
424 CARDIAC ARREST 3144 0.0450
425 WEIGHT DECREASED 10207 0.0450
426 URINARY RETENTION 1209 0.0450
427 TOOTH DISORDER 852 0.0449
428 LACTIC ACIDOSIS 1065 0.0448
429 GINGIVAL PAIN 291 0.0446
430 LABORATORY TEST ABNORMAL 1058 0.0446
431 JOINT EFFUSION 262 0.0445
432 ERECTILE DYSFUNCTION 913 0.0444
433 METABOLIC ACIDOSIS 1106 0.0444
434 ESCHERICHIA INFECTION 278 0.0443
435 MALNUTRITION 382 0.0443
436 BACK INJURY 354 0.0443
437 PULMONARY THROMBOSIS 383 0.0443
438 COLD SWEAT 650 0.0443
439 ORAL CANDIDIASIS 442 0.0442
440 BLADDER DISORDER 371 0.0441
441 PELVIC FRACTURE 277 0.0440
442 DRUG TOXICITY 600 0.0440
443 HYPOTHYROIDISM 1080 0.0439
444 PALLOR 1015 0.0439
445 DIZZINESS 17905 0.0439
446 ALANINE AMINOTRANSFERASE INCREASED 2260 0.0438
447 EMBOLISM 308 0.0438
448 GLYCOSYLATED HAEMOGLOBIN INCREASED 863 0.0437
449 PNEUMONIA ASPIRATION 870 0.0437
450 PROCEDURAL COMPLICATION 299 0.0437
451 GLAUCOMA 693 0.0436
452 SINUS CONGESTION 483 0.0436
453 OXYGEN SATURATION DECREASED 1832 0.0435
454 GENERAL PHYSICAL HEALTH DETERIORATION 3688 0.0435
455 SPUTUM DISCOLOURED 323 0.0434
456 BACK PAIN 8332 0.0434
457 DYSPHONIA 2035 0.0434
458 PRURITUS GENERALISED 940 0.0434
459 MUSCLE SPASMS 6558 0.0433
460 MASS 508 0.0431
461 LETHARGY 2080 0.0431
462 DIPLOPIA 897 0.0431
463 DISORIENTATION 1479 0.0431
464 SENSATION OF FOREIGN BODY 282 0.0430
465 RESPIRATORY TRACT INFECTION 841 0.0430
466 UPPER-AIRWAY COUGH SYNDROME 269 0.0429
467 NECK PAIN 1951 0.0428
468 NIGHT SWEATS 1069 0.0428
469 JOINT DISLOCATION 355 0.0426
470 ASPIRATION 360 0.0425
471 THYROID DISORDER 526 0.0425
472 EATING DISORDER 754 0.0425
473 SPINAL DISORDER 333 0.0425
474 BLOOD GLUCOSE DECREASED 1757 0.0425
475 FLUID RETENTION 1799 0.0425
476 TRANSFUSION 375 0.0425
477 CARDIOVASCULAR DISORDER 983 0.0424
478 CHOLECYSTITIS 408 0.0424
479 ORAL PAIN 795 0.0423
480 ANURIA 318 0.0423
481 COVID-19 PNEUMONIA 375 0.0422
482 DECREASED APPETITE 7639 0.0422
483 OSTEOMYELITIS 659 0.0421
484 JOINT RANGE OF MOTION DECREASED 399 0.0421
485 RESTLESS LEGS SYNDROME 643 0.0421
486 FLATULENCE 1905 0.0420
487 PAIN IN EXTREMITY 10442 0.0420
488 ARTHRITIS 2670 0.0419
489 HALLUCINATION, VISUAL 681 0.0419
490 DYSPHAGIA 3136 0.0419
491 HYPERTENSIVE CRISIS 393 0.0418
492 ASPARTATE AMINOTRANSFERASE INCREASED 1867 0.0418
493 HEART RATE INCREASED 3370 0.0417
494 MOTOR DYSFUNCTION 342 0.0417
495 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 333 0.0414
496 RENAL DISORDER 1586 0.0414
497 HYPERHIDROSIS 4498 0.0414
498 PLATELET COUNT DECREASED 3557 0.0414
499 BURNING SENSATION 2428 0.0413
500 SEPSIS 3775 0.0413
501 DRY MOUTH 2667 0.0413
502 WEIGHT FLUCTUATION 326 0.0413
503 GENERALISED OEDEMA 402 0.0413
504 UPPER RESPIRATORY TRACT INFECTION 1517 0.0412
505 PERIPHERAL SWELLING 4895 0.0412
506 ABASIA 1018 0.0411
507 DYSSTASIA 1010 0.0411
508 COUGH 9004 0.0411
509 SECRETION DISCHARGE 370 0.0411
510 LOSS OF CONSCIOUSNESS 4372 0.0410
511 PURPURA 305 0.0408
512 GAIT DISTURBANCE 6510 0.0408
513 HERNIA 616 0.0408
514 FOOT FRACTURE 650 0.0407
515 C-REACTIVE PROTEIN INCREASED 1147 0.0406
516 BLINDNESS UNILATERAL 464 0.0405
517 HOT FLUSH 2298 0.0405
518 BLOOD GLUCOSE INCREASED 6532 0.0405
519 SUDDEN DEATH 382 0.0404
520 WHITE BLOOD CELL COUNT DECREASED 3532 0.0403
521 TOOTH FRACTURE 372 0.0403
522 TOOTHACHE 594 0.0403
523 TINNITUS 1515 0.0402
524 OSTEOPOROSIS 1389 0.0402
525 DECREASED ACTIVITY 334 0.0402
526 NEPHROLITHIASIS 1436 0.0401
527 GALLBLADDER DISORDER 619 0.0401
528 LIMB DISCOMFORT 1008 0.0401
529 SKIN DISCOLOURATION 1517 0.0400
530 THROMBOCYTOPENIA 3546 0.0399
531 FEELING COLD 922 0.0399
532 TOXIC EPIDERMAL NECROLYSIS 478 0.0398
533 PRURITUS 10853 0.0397
534 DEAFNESS 827 0.0397
535 FACIAL PAIN 285 0.0397
536 DELIRIUM 1077 0.0396
537 DIALYSIS 479 0.0396
538 PARAESTHESIA ORAL 452 0.0395
539 TASTE DISORDER 464 0.0395
540 FEEDING DISORDER 537 0.0395
541 IMPAIRED HEALING 1016 0.0395
542 DIARRHOEA 19921 0.0395
543 DEPRESSED LEVEL OF CONSCIOUSNESS 1300 0.0394
544 BLOOD LACTATE DEHYDROGENASE INCREASED 550 0.0394
545 SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION 282 0.0392
546 HALLUCINATION 2287 0.0392
547 HYPOAESTHESIA 4851 0.0392
548 SHOCK 702 0.0391
549 TOOTH INFECTION 416 0.0391
550 INITIAL INSOMNIA 301 0.0390
551 NEUTROPHIL COUNT INCREASED 332 0.0390
552 RHINORRHOEA 1945 0.0389
553 PALPITATIONS 3739 0.0389
554 FATIGUE 24010 0.0388
555 LIP SWELLING 1061 0.0388
556 PULMONARY EMBOLISM 3194 0.0388
557 COGNITIVE DISORDER 1460 0.0387
558 ARTHROPATHY 1755 0.0387
559 MUSCLE DISORDER 273 0.0386
560 STAPHYLOCOCCAL INFECTION 1085 0.0385
561 JAUNDICE 900 0.0384
562 VITREOUS FLOATERS 280 0.0384
563 AMNESIA 2141 0.0384
564 NERVE INJURY 361 0.0383
565 RESPIRATORY TRACT CONGESTION 476 0.0381
566 PNEUMOTHORAX 481 0.0380
567 PREMATURE DELIVERY 502 0.0377
568 DIARRHOEA HAEMORRHAGIC 290 0.0377
569 MOBILITY DECREASED 2149 0.0376
570 RESPIRATORY DISTRESS 866 0.0376
571 WRIST FRACTURE 371 0.0376
572 PRODUCT PRESCRIBING ERROR 602 0.0375
573 SKIN LESION 807 0.0375
574 GASTROENTERITIS VIRAL 523 0.0374
575 SEPTIC SHOCK 1257 0.0374
576 NASAL CONGESTION 1671 0.0374
577 GAMMA-GLUTAMYLTRANSFERASE INCREASED 721 0.0373
578 PHARYNGEAL OEDEMA 566 0.0373
579 RASH PRURITIC 1573 0.0373
580 TOOTH ABSCESS 326 0.0372
581 TEMPERATURE INTOLERANCE 293 0.0371
582 TENDON RUPTURE 392 0.0370
583 KNEE ARTHROPLASTY 559 0.0370
584 SPINAL FRACTURE 579 0.0369
585 TENDONITIS 490 0.0369
586 ANKLE FRACTURE 475 0.0369
587 ABDOMINAL PAIN UPPER 6058 0.0368
588 BACTERAEMIA 330 0.0368
589 CHOKING 562 0.0366
590 EAR PAIN 576 0.0366
591 CLOSTRIDIUM DIFFICILE INFECTION 606 0.0365
592 ABDOMINAL DISTENSION 3013 0.0365
593 RASH MACULAR 985 0.0365
594 PAIN IN JAW 880 0.0364
595 BLOOD BILIRUBIN INCREASED 837 0.0364
596 TACHYCARDIA 2637 0.0364
597 LIGAMENT SPRAIN 282 0.0363
598 SPEECH DISORDER 1588 0.0362
599 HAIR DISORDER 286 0.0362
600 CYST 367 0.0362
601 HYPERSOMNIA 837 0.0361
602 DELUSION 443 0.0361
603 DENTAL CARIES 336 0.0361
604 PROTEINURIA 516 0.0361
605 MALIGNANT MELANOMA 401 0.0361
606 ACTIVITIES OF DAILY LIVING IMPAIRED 715 0.0360
607 EAR DISCOMFORT 291 0.0360
608 VISUAL ACUITY REDUCED 1113 0.0360
609 HEPATOMEGALY 309 0.0360
610 SINUSITIS 2987 0.0359
611 PRESCRIBED UNDERDOSE 559 0.0359
612 BLOOD COUNT ABNORMAL 554 0.0358
613 CHILLS 3463 0.0358
614 EYE INFECTION 302 0.0358
615 PANCYTOPENIA 1581 0.0358
616 NEURALGIA 684 0.0357
617 DRY THROAT 295 0.0357
618 PANCREATITIS 1565 0.0357
619 RENAL PAIN 308 0.0357
620 CARDIO-RESPIRATORY ARREST 1300 0.0356
621 SWELLING FACE 1895 0.0355
622 WOUND 720 0.0355
623 VERTIGO 1808 0.0355
624 COLITIS 988 0.0354
625 PARKINSONISM 268 0.0354
626 UPPER LIMB FRACTURE 612 0.0354
627 HERPES ZOSTER 1667 0.0353
628 DYSGEUSIA 2265 0.0351
629 HEAD DISCOMFORT 476 0.0351
630 ILEUS 340 0.0351
631 ABDOMINAL PAIN 6595 0.0350
632 ABDOMINAL DISCOMFORT 4634 0.0349
633 EAR INFECTION 699 0.0349
634 CYANOSIS 458 0.0347
635 VISION BLURRED 3801 0.0346
636 ENCEPHALOPATHY 680 0.0346
637 JOINT SWELLING 3284 0.0346
638 POOR QUALITY SLEEP 577 0.0345
639 HAIR COLOUR CHANGES 391 0.0344
640 POLYNEUROPATHY 311 0.0344
641 VIRAL INFECTION 873 0.0343
642 BLOOD THYROID STIMULATING HORMONE INCREASED 261 0.0342
643 INSOMNIA 7611 0.0342
644 GASTRIC DISORDER 1180 0.0342
645 TREMOR 4776 0.0342
646 ANHEDONIA 836 0.0342
647 RETCHING 582 0.0341
648 BLOOD TEST ABNORMAL 368 0.0340
649 MUSCLE SPASTICITY 371 0.0340
650 ADRENAL INSUFFICIENCY 274 0.0339
651 SENSORY DISTURBANCE 479 0.0338
652 TREATMENT NONCOMPLIANCE 1355 0.0338
653 EYELID PTOSIS 267 0.0336
654 LOWER RESPIRATORY TRACT INFECTION 1103 0.0336
655 MUSCLE TIGHTNESS 455 0.0335
656 SCAR 479 0.0333
657 EOSINOPHILIA 458 0.0332
658 BONE PAIN 1607 0.0332
659 NO THERAPEUTIC RESPONSE 405 0.0332
660 ARTHRALGIA 10734 0.0332
661 DEVICE OCCLUSION 301 0.0331
662 BACTERIAL INFECTION 471 0.0331
663 HYPOTHERMIA 275 0.0331
664 RASH GENERALISED 857 0.0330
665 MEMORY IMPAIRMENT 3746 0.0330
666 PNEUMONITIS 662 0.0329
667 DRUG ERUPTION 449 0.0329
668 BODY TEMPERATURE INCREASED 571 0.0328
669 DISSEMINATED INTRAVASCULAR COAGULATION 398 0.0328
670 STRESS 1871 0.0328
671 HYPERTHYROIDISM 370 0.0327
672 GAIT INABILITY 718 0.0327
673 EYE DISORDER 855 0.0327
674 NAUSEA 20855 0.0326
675 HAIR TEXTURE ABNORMAL 399 0.0325
676 HYPOACUSIS 1065 0.0324
677 MUSCULOSKELETAL DISORDER 532 0.0324
678 SCAB 291 0.0323
679 VOMITING 12125 0.0323
680 NODULE 340 0.0322
681 FIBROMYALGIA 592 0.0321
682 LOCAL SWELLING 560 0.0321
683 FOOT DEFORMITY 285 0.0320
684 SLEEP DISORDER 1701 0.0320
685 NERVOUSNESS 1480 0.0320
686 BLOOD GLUCOSE ABNORMAL 487 0.0320
687 RASH ERYTHEMATOUS 1078 0.0320
688 MYELODYSPLASTIC SYNDROME 383 0.0320
689 SNEEZING 547 0.0319
690 LIVER DISORDER 1124 0.0319
691 MOVEMENT DISORDER 857 0.0318
692 PERICARDITIS 343 0.0318
693 DEPRESSION 6223 0.0317
694 SKIN CANCER 549 0.0317
695 GRAND MAL CONVULSION 293 0.0317
696 DYSKINESIA 1069 0.0316
697 LACRIMATION INCREASED 702 0.0316
698 NEUTROPHIL COUNT DECREASED 969 0.0316
699 KIDNEY INFECTION 497 0.0315
700 STOMATITIS 1506 0.0315
701 SKIN INFECTION 271 0.0315
702 MOUTH ULCERATION 519 0.0314
703 MUSCLE TWITCHING 610 0.0314
704 INJECTION SITE NODULE 294 0.0314
705 RESTLESSNESS 966 0.0314
706 HIP ARTHROPLASTY 351 0.0314
707 DIABETIC KETOACIDOSIS 617 0.0314
708 SLUGGISHNESS 264 0.0313
709 HEPATIC ENZYME INCREASED 1643 0.0313
710 ASTHMA 2505 0.0313
711 BLISTER 1368 0.0312
712 IRRITABLE BOWEL SYNDROME 485 0.0312
713 LUNG DISORDER 1193 0.0311
714 ALTERED STATE OF CONSCIOUSNESS 512 0.0310
715 LARYNGITIS 261 0.0310
716 FREQUENT BOWEL MOVEMENTS 601 0.0310
717 ACUTE RESPIRATORY DISTRESS SYNDROME 443 0.0306
718 EYE PAIN 1236 0.0306
719 COLON CANCER 376 0.0306
720 ASCITES 741 0.0305
721 RESPIRATORY DISORDER 743 0.0305
722 PYREXIA 8625 0.0305
723 CHOLECYSTECTOMY 278 0.0305
724 INJURY 1905 0.0305
725 INFLUENZA 2539 0.0305
726 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 1000 0.0304
727 OROPHARYNGEAL PAIN 2259 0.0304
728 CANDIDA INFECTION 380 0.0304
729 SOMNOLENCE 5003 0.0304
730 ERYTHEMA 5098 0.0304
731 ABDOMINAL PAIN LOWER 644 0.0304
732 CONVULSION 1738 0.0304
733 WEIGHT INCREASED 5432 0.0303
734 FEAR 739 0.0303
735 DRUG LEVEL INCREASED 410 0.0303
736 BRONCHOSPASM 364 0.0302
737 LOWER LIMB FRACTURE 432 0.0302
738 THROAT IRRITATION 1065 0.0302
739 DERMATITIS ALLERGIC 281 0.0302
740 SEDATION 597 0.0302
741 CONTRAINDICATED PRODUCT ADMINISTERED 682 0.0301
742 NASOPHARYNGITIS 4317 0.0301
743 BREAST PAIN 278 0.0301
744 MYOCLONUS 296 0.0300
745 HYPOAESTHESIA ORAL 375 0.0300
746 HEPATIC CIRRHOSIS 432 0.0300
747 MUSCULOSKELETAL STIFFNESS 2146 0.0300
748 JOINT STIFFNESS 645 0.0299
749 BEDRIDDEN 327 0.0299
750 ELECTROCARDIOGRAM QT PROLONGED 857 0.0299
751 HEPATITIS 620 0.0299
752 PULMONARY ARTERIAL HYPERTENSION 374 0.0298
753 ABNORMAL DREAMS 731 0.0297
754 THERAPY CESSATION 1162 0.0296
755 PARALYSIS 354 0.0295
756 LUNG INFECTION 460 0.0295
757 ROAD TRAFFIC ACCIDENT 1001 0.0294
758 IMMUNE SYSTEM DISORDER 307 0.0293
759 FEMUR FRACTURE 793 0.0293
760 ANXIETY 7021 0.0293
761 LYMPHOCYTE COUNT DECREASED 423 0.0292
762 PHOTOPHOBIA 421 0.0292
763 DRUG-INDUCED LIVER INJURY 592 0.0291
764 FEELING ABNORMAL 6020 0.0291
765 ANAPHYLACTIC REACTION 1203 0.0291
766 FEELING JITTERY 478 0.0290
767 RASH PAPULAR 558 0.0290
768 EYELID OEDEMA 306 0.0289
769 PHOTOSENSITIVITY REACTION 392 0.0289
770 BLINDNESS 930 0.0288
771 ORAL DISCOMFORT 331 0.0287
772 LEUKOPENIA 1146 0.0287
773 LIVER INJURY 441 0.0285
774 IMPAIRED DRIVING ABILITY 274 0.0284
775 HEADACHE 14607 0.0284
776 THROAT TIGHTNESS 631 0.0284
777 SKIN DISORDER 742 0.0284
778 STEVENS-JOHNSON SYNDROME 540 0.0283
779 SYNOVITIS 372 0.0282
780 CONDITION AGGRAVATED 6311 0.0282
781 PHARMACEUTICAL PRODUCT COMPLAINT 733 0.0282
782 AGITATION 1781 0.0282
783 RASH 9505 0.0282
784 ECZEMA 677 0.0281
785 APHONIA 305 0.0281
786 SWELLING 2088 0.0280
787 THIRST 405 0.0280
788 ILL-DEFINED DISORDER 985 0.0279
789 UNEVALUABLE EVENT 1829 0.0279
790 LYMPHADENOPATHY 803 0.0279
791 BRAIN OEDEMA 288 0.0279
792 DRUG HYPERSENSITIVITY 4545 0.0278
793 PREMATURE BABY 707 0.0277
794 MALAISE 10230 0.0277
795 INCREASED APPETITE 372 0.0276
796 INJECTION SITE HAEMORRHAGE 1692 0.0276
797 COVID-19 3389 0.0275
798 MADAROSIS 299 0.0275
799 MULTIPLE ORGAN DYSFUNCTION SYNDROME 528 0.0275
800 COMA 1090 0.0274
801 ABSCESS 353 0.0274
802 DRY EYE 876 0.0273
803 METASTASES TO BONE 334 0.0273
804 CONJUNCTIVITIS 362 0.0273
805 MUSCLE RIGIDITY 266 0.0273
806 EYE SWELLING 803 0.0271
807 NEUTROPENIA 2793 0.0271
808 VISUAL IMPAIRMENT 2570 0.0271
809 GASTROINTESTINAL DISORDER 1637 0.0271
810 RASH MACULO-PAPULAR 470 0.0270
811 PAIN 13893 0.0270
812 INTRAOCULAR PRESSURE INCREASED 292 0.0269
813 DISEASE RECURRENCE 894 0.0269
814 SKIN BURNING SENSATION 1594 0.0268
815 PERITONITIS 471 0.0268
816 INTESTINAL OBSTRUCTION 764 0.0267
817 DEPRESSED MOOD 1116 0.0267
818 INJECTION SITE HAEMATOMA 373 0.0267
819 MENTAL IMPAIRMENT 535 0.0266
820 GLOSSODYNIA 444 0.0265
821 HEPATIC FUNCTION ABNORMAL 757 0.0264
822 DISTURBANCE IN ATTENTION 1204 0.0263
823 WRONG TECHNIQUE IN DRUG USAGE PROCESS 956 0.0263
824 HEPATIC FAILURE 667 0.0263
825 ACUTE HEPATIC FAILURE 275 0.0263
826 INFLAMMATION 1013 0.0262
827 INFECTION 2897 0.0261
828 NIGHTMARE 758 0.0258
829 INJECTION SITE BRUISING 1570 0.0257
830 TOOTH EXTRACTION 270 0.0257
831 IMMUNODEFICIENCY 262 0.0257
832 MEDICATION ERROR 1167 0.0255
833 FUNGAL INFECTION 685 0.0255
834 INFLUENZA LIKE ILLNESS 1805 0.0254
835 PARANOIA 372 0.0254
836 APATHY 298 0.0252
837 THINKING ABNORMAL 413 0.0252
838 METASTASES TO LIVER 348 0.0252
839 LIVER FUNCTION TEST INCREASED 373 0.0251
840 THERAPEUTIC RESPONSE UNEXPECTED 953 0.0250
841 INTERSTITIAL LUNG DISEASE 940 0.0250
842 CHOLESTASIS 376 0.0249
843 DISEASE PROGRESSION 2226 0.0247
844 DRUG INTOLERANCE 1821 0.0245
845 DISCOMFORT 1088 0.0244
846 DRUG ADMINISTRATION ERROR 751 0.0244
847 URTICARIA 3167 0.0244
848 FACE OEDEMA 346 0.0243
849 TRANSAMINASES INCREASED 447 0.0242
850 ANOSMIA 290 0.0241
851 QUALITY OF LIFE DECREASED 265 0.0241
852 DERMATITIS 364 0.0240
853 PRODUCT ADMINISTRATION ERROR 313 0.0240
854 PROCEDURAL PAIN 512 0.0239
855 INTENTIONAL PRODUCT USE ISSUE 1553 0.0237
856 IMPAIRED WORK ABILITY 436 0.0235
857 PRODUCT AVAILABILITY ISSUE 269 0.0235
858 ADVERSE DRUG REACTION 1540 0.0234
859 DEVICE RELATED INFECTION 311 0.0234
860 AGRANULOCYTOSIS 327 0.0233
861 THERAPY INTERRUPTED 746 0.0231
862 FRACTURE 363 0.0231
863 SKIN FISSURES 267 0.0231
864 FEBRILE NEUTROPENIA 1167 0.0230
865 MENTAL DISORDER 819 0.0229
866 INFUSION RELATED REACTION 1109 0.0228
867 ILLNESS 1121 0.0228
868 INJECTION SITE EXTRAVASATION 264 0.0225
869 SKIN EXFOLIATION 1413 0.0224
870 OCULAR HYPERAEMIA 769 0.0224
871 EYE PRURITUS 507 0.0224
872 DRUG PRESCRIBING ERROR 430 0.0223
873 INTENTIONAL DRUG MISUSE 467 0.0223
874 DRUG DOSE OMISSION 3697 0.0223
875 PRESCRIBED OVERDOSE 345 0.0223
876 RESPIRATORY ARREST 553 0.0221
877 HYPERSENSITIVITY 3306 0.0219
878 INTENTIONAL PRODUCT MISUSE 1541 0.0219
879 MUCOSAL INFLAMMATION 457 0.0219
880 PANIC ATTACK 659 0.0219
881 HEPATOTOXICITY 376 0.0217
882 NERVOUS SYSTEM DISORDER 593 0.0216
883 RHEUMATOID ARTHRITIS 1944 0.0216
884 MULTIPLE FRACTURES 318 0.0215
885 OSTEONECROSIS OF JAW 466 0.0211
886 DRUG EFFECT DECREASED 1126 0.0209
887 SURGERY 865 0.0208
888 LYMPHOMA 269 0.0206
889 LUNG NEOPLASM MALIGNANT 746 0.0205
890 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 1458 0.0205
891 ACCIDENTAL OVERDOSE 565 0.0203
892 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 386 0.0203
893 ORAL HERPES 299 0.0202
894 SEROTONIN SYNDROME 288 0.0199
895 DRY SKIN 1917 0.0197
896 AGGRESSION 848 0.0197
897 ABNORMAL BEHAVIOUR 701 0.0197
898 INCORRECT DRUG ADMINISTRATION DURATION 553 0.0196
899 PRODUCT DOSE OMISSION ISSUE 2780 0.0196
900 COLITIS ULCERATIVE 591 0.0196
901 MIGRAINE 1449 0.0195
902 OFF LABEL USE 11438 0.0195
903 EMOTIONAL DISORDER 511 0.0195
904 ANGER 569 0.0193
905 PSORIATIC ARTHROPATHY 527 0.0192
906 PRODUCT DOSE OMISSION 1273 0.0192
907 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 932 0.0191
908 DRUG DISPENSING ERROR 292 0.0191
909 PRODUCT QUALITY ISSUE 2319 0.0191
910 ALOPECIA 3133 0.0191
911 SEIZURE 1622 0.0190
912 THERAPY NON-RESPONDER 576 0.0190
913 ANAPHYLACTIC SHOCK 374 0.0190
914 PSYCHOMOTOR HYPERACTIVITY 274 0.0188
915 PSORIASIS 2023 0.0188
916 INJECTION SITE MASS 533 0.0187
917 MULTIPLE SCLEROSIS 755 0.0187
918 EYE IRRITATION 728 0.0185
919 PRODUCT PHYSICAL ISSUE 278 0.0185
920 BONE MARROW FAILURE 344 0.0184
921 PAIN OF SKIN 413 0.0182
922 INCORRECT DOSE ADMINISTERED 2731 0.0180
923 IRRITABILITY 925 0.0179
924 PSYCHOTIC DISORDER 439 0.0179
925 OSTEONECROSIS 529 0.0177
926 MALIGNANT NEOPLASM PROGRESSION 1365 0.0176
927 EPILEPSY 412 0.0174
928 THERAPEUTIC RESPONSE DECREASED 801 0.0170
929 CRYING 539 0.0169
930 THERAPEUTIC PRODUCT EFFECT DECREASED 524 0.0169
931 SYSTEMIC LUPUS ERYTHEMATOSUS 408 0.0168
932 THERAPEUTIC RESPONSE SHORTENED 267 0.0167
933 MOOD ALTERED 370 0.0167
934 FOETAL EXPOSURE DURING PREGNANCY 1059 0.0166
935 ADVERSE EVENT 1250 0.0166
936 EXPOSURE DURING PREGNANCY 798 0.0166
937 UNDERDOSE 965 0.0165
938 TOOTH LOSS 295 0.0164
939 TOXICITY TO VARIOUS AGENTS 2149 0.0164
940 PRODUCT SUBSTITUTION ISSUE 794 0.0163
941 DEATH 11129 0.0162
942 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 645 0.0161
943 INTENTIONAL OVERDOSE 777 0.0159
944 VAGINAL HAEMORRHAGE 594 0.0159
945 MATERNAL EXPOSURE DURING PREGNANCY 987 0.0157
946 BONE DENSITY DECREASED 440 0.0155
947 SUICIDAL IDEATION 1176 0.0155
948 HOSPITALISATION 1696 0.0154
949 DRUG INEFFECTIVE 16331 0.0154
950 PRODUCT USE ISSUE 2203 0.0154
951 DRUG RESISTANCE 304 0.0153
952 MULTIPLE SCLEROSIS RELAPSE 938 0.0151
953 EMOTIONAL DISTRESS 1649 0.0147
954 NEOPLASM PROGRESSION 425 0.0147
955 SUICIDE ATTEMPT 730 0.0147
956 NEEDLE ISSUE 270 0.0145
957 APPLICATION SITE ERYTHEMA 345 0.0145
958 DRUG EFFECT INCOMPLETE 529 0.0145
959 MOOD SWINGS 398 0.0144
960 PRODUCT USE IN UNAPPROVED INDICATION 2329 0.0144
961 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 1523 0.0144
962 DEVICE MALFUNCTION 680 0.0142
963 APPLICATION SITE PRURITUS 280 0.0141
964 EXTRAPYRAMIDAL DISORDER 323 0.0140
965 NEOPLASM MALIGNANT 709 0.0136
966 PANCREATIC CARCINOMA 353 0.0134
967 INJECTION SITE PAIN 2897 0.0129
968 OVERDOSE 2268 0.0129
969 INJECTION SITE PRURITUS 661 0.0124
970 WITHDRAWAL SYNDROME 394 0.0123
971 TARDIVE DYSKINESIA 320 0.0122
972 EXTRA DOSE ADMINISTERED 282 0.0121
973 INJECTION SITE ERYTHEMA 1203 0.0120
974 EXPIRED PRODUCT ADMINISTERED 320 0.0119
975 INJECTION SITE RASH 264 0.0116
976 DEVICE ISSUE 708 0.0115
977 DEVICE LEAKAGE 261 0.0114
978 COMPLETED SUICIDE 831 0.0114
979 DRUG EXPOSURE DURING PREGNANCY 381 0.0112
980 BREAST CANCER FEMALE 264 0.0107
981 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 1512 0.0101
982 PRODUCT ADHESION ISSUE 269 0.0100
983 TREATMENT FAILURE 602 0.0098
984 INJECTION SITE SWELLING 565 0.0098
985 DEVICE DISLOCATION 349 0.0098
986 PROSTATE CANCER 743 0.0097
987 SKIN IRRITATION 375 0.0096
988 ABORTION SPONTANEOUS 323 0.0095
989 INCORRECT ROUTE OF DRUG ADMINISTRATION 318 0.0089
990 BREAST CANCER 767 0.0088
991 INJECTION SITE REACTION 484 0.0086
992 ACNE 523 0.0079
993 BLADDER CANCER 395 0.0069
994 DRUG WITHDRAWAL SYNDROME 570 0.0068
995 NO ADVERSE EVENT 742 0.0062
996 DRUG ABUSE 320 0.0046
997 DRUG DEPENDENCE 414 0.0027