OMEPRAZOLE

OMEPRAZOLE was reported 316686 times

OMEPRAZOLE is most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 HYPERTENSIVE NEPHROPATHY 279 0.3568
1 CHRONIC KIDNEY DISEASE-MINERAL AND BONE DISORDER 161 0.2317
2 END STAGE RENAL DISEASE 2942 0.2129
3 NEPHROGENIC ANAEMIA 693 0.2019
4 CHRONIC KIDNEY DISEASE 10816 0.1953
5 DIABETIC NEPHROPATHY 311 0.1866
6 HYPOMAGNESAEMIA 1452 0.1785
7 SUBACUTE CUTANEOUS LUPUS ERYTHEMATOSUS 163 0.1693
8 NEPHROSCLEROSIS 148 0.1689
9 REBOUND ACID HYPERSECRETION 410 0.1559
10 HYPERPARATHYROIDISM SECONDARY 259 0.1426
11 TETANY 185 0.1423
12 TUBULOINTERSTITIAL NEPHRITIS 1634 0.1385
13 RENAL INJURY 2617 0.1055
14 NEPHROPATHY 645 0.1043
15 ACUTE KIDNEY INJURY 8391 0.0958
16 HYPOCALCAEMIA 1070 0.0865
17 NEUTROPENIC SEPSIS 391 0.0788
18 RENAL CYST 421 0.0748
19 INFECTIVE PULMONARY EXACERBATION OF CYSTIC FIBROSIS 325 0.0739
20 ABNORMAL LOSS OF WEIGHT 344 0.0711
21 BLOOD MAGNESIUM DECREASED 361 0.0690
22 HYPONATRAEMIA 2619 0.0674
23 HYPERCHLORHYDRIA 303 0.0654
24 IRON DEFICIENCY ANAEMIA 408 0.0650
25 GASTROOESOPHAGEAL REFLUX DISEASE 3329 0.0634
26 HIATUS HERNIA 613 0.0631
27 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 420 0.0627
28 ABDOMINAL TENDERNESS 223 0.0625
29 CREATININE RENAL CLEARANCE DECREASED 175 0.0621
30 RENAL FAILURE 6047 0.0610
31 VITAMIN B12 DEFICIENCY 145 0.0602
32 OESOPHAGITIS 454 0.0601
33 GASTRITIS 1094 0.0600
34 HELICOBACTER INFECTION 182 0.0589
35 BLOOD CALCIUM DECREASED 432 0.0559
36 JAUNDICE CHOLESTATIC 142 0.0555
37 UPPER GASTROINTESTINAL HAEMORRHAGE 693 0.0554
38 ORTHOSTATIC HYPOTENSION 633 0.0553
39 AZOTAEMIA 146 0.0540
40 POLYURIA 293 0.0538
41 HEPATIC ENCEPHALOPATHY 354 0.0532
42 VITAMIN D DEFICIENCY 324 0.0528
43 CLOSTRIDIUM DIFFICILE COLITIS 367 0.0521
44 PRE-EXISTING CONDITION IMPROVED 275 0.0517
45 DRUG INTERACTION 5602 0.0514
46 HYPOKALAEMIA 1518 0.0509
47 SLEEP APNOEA SYNDROME 672 0.0501
48 CYTOLYTIC HEPATITIS 166 0.0498
49 BRONCHOPNEUMONIA 171 0.0498
50 NEUTROPHIL COUNT INCREASED 355 0.0497
51 TOXIC EPIDERMAL NECROLYSIS 490 0.0491
52 PROTEINURIA 543 0.0490
53 LABELLED DRUG-DRUG INTERACTION MEDICATION ERROR 300 0.0488
54 NOCTURIA 356 0.0482
55 BLOOD SODIUM DECREASED 603 0.0482
56 SPINAL OSTEOARTHRITIS 305 0.0482
57 RENAL FAILURE ACUTE 2046 0.0481
58 HEPATITIS CHOLESTATIC 196 0.0480
59 GASTRITIS EROSIVE 170 0.0477
60 HAEMORRHAGIC ANAEMIA 210 0.0474
61 CLOSTRIDIUM DIFFICILE INFECTION 595 0.0474
62 BLOOD CHOLESTEROL ABNORMAL 140 0.0473
63 INTERVERTEBRAL DISC DEGENERATION 325 0.0472
64 DIALYSIS 498 0.0472
65 FAECALOMA 163 0.0472
66 IMMUNODEFICIENCY 333 0.0470
67 HAEMATEMESIS 851 0.0465
68 HYPERKALAEMIA 1101 0.0464
69 DIVERTICULUM 281 0.0463
70 ATRIAL FLUTTER 266 0.0459
71 BUNDLE BRANCH BLOCK LEFT 146 0.0457
72 PULMONARY FUNCTION TEST DECREASED 140 0.0456
73 OSTEOPENIA 416 0.0455
74 HYPOVOLAEMIC SHOCK 146 0.0453
75 LOWER RESPIRATORY TRACT INFECTION 1164 0.0451
76 RALES 174 0.0449
77 RENAL IMPAIRMENT 2250 0.0448
78 PLATELET COUNT INCREASED 362 0.0446
79 LOWER GASTROINTESTINAL HAEMORRHAGE 260 0.0442
80 ELECTROLYTE IMBALANCE 317 0.0442
81 HYDRONEPHROSIS 219 0.0441
82 OLIGURIA 194 0.0438
83 PYELONEPHRITIS 244 0.0438
84 RENAL TUBULAR NECROSIS 282 0.0434
85 HYPOPHOSPHATAEMIA 189 0.0434
86 OSTEOARTHRITIS 1170 0.0434
87 INTESTINAL ISCHAEMIA 163 0.0433
88 ACUTE RESPIRATORY FAILURE 484 0.0433
89 INTERNATIONAL NORMALISED RATIO INCREASED 1089 0.0430
90 ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS 213 0.0430
91 ORAL CANDIDIASIS 350 0.0430
92 SPLENOMEGALY 343 0.0429
93 LIVER FUNCTION TEST ABNORMAL 1035 0.0429
94 HYPOPHAGIA 692 0.0428
95 MELAENA 677 0.0427
96 DUODENAL ULCER 215 0.0426
97 RHINITIS 216 0.0424
98 BODY HEIGHT DECREASED 364 0.0423
99 SEROTONIN SYNDROME 498 0.0420
100 UROSEPSIS 248 0.0418
101 AMMONIA INCREASED 159 0.0417
102 IMPAIRED GASTRIC EMPTYING 201 0.0415
103 BLOOD ALBUMIN DECREASED 239 0.0414
104 ODYNOPHAGIA 155 0.0412
105 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 1487 0.0411
106 HAIR DISORDER 306 0.0411
107 DIABETIC NEUROPATHY 161 0.0410
108 URINE OUTPUT DECREASED 266 0.0409
109 SMALL INTESTINAL OBSTRUCTION 331 0.0409
110 CHOLECYSTITIS 340 0.0409
111 PATHOLOGICAL FRACTURE 141 0.0406
112 MOUTH SWELLING 138 0.0406
113 ATELECTASIS 292 0.0405
114 POSTOPERATIVE WOUND INFECTION 166 0.0405
115 ERYSIPELAS 139 0.0403
116 BLOOD POTASSIUM DECREASED 811 0.0402
117 PANCREATITIS ACUTE 594 0.0401
118 ANAL INCONTINENCE 170 0.0401
119 FAECES DISCOLOURED 613 0.0401
120 HAEMATURIA 1000 0.0397
121 CHOLESTASIS 489 0.0396
122 HEPATIC STEATOSIS 489 0.0395
123 BLOOD IRON DECREASED 249 0.0394
124 HEPATITIS ACUTE 179 0.0394
125 FAILURE TO THRIVE 156 0.0394
126 CHOLANGITIS 143 0.0394
127 GLOMERULAR FILTRATION RATE DECREASED 247 0.0392
128 BENIGN PROSTATIC HYPERPLASIA 143 0.0392
129 CANDIDA INFECTION 358 0.0391
130 MALNUTRITION 276 0.0391
131 SUPRAVENTRICULAR TACHYCARDIA 266 0.0391
132 HAEMATOCRIT DECREASED 592 0.0390
133 BLOOD UREA INCREASED 521 0.0390
134 SQUAMOUS CELL CARCINOMA OF SKIN 138 0.0387
135 ORAL PAIN 585 0.0387
136 POLYP 165 0.0386
137 CHOLECYSTITIS CHRONIC 248 0.0386
138 MOUTH ULCERATION 506 0.0385
139 DYSPNOEA EXERTIONAL 856 0.0384
140 GASTROENTERITIS 385 0.0383
141 RECTAL HAEMORRHAGE 1177 0.0382
142 KIDNEY INFECTION 468 0.0382
143 PSYCHOLOGICAL TRAUMA 302 0.0382
144 CARPAL TUNNEL SYNDROME 351 0.0381
145 RENAL PAIN 260 0.0381
146 ELECTROCARDIOGRAM QT PROLONGED 872 0.0381
147 GASTRIC ULCER 524 0.0381
148 CHROMATURIA 617 0.0380
149 SPINAL COMPRESSION FRACTURE 229 0.0379
150 MYOSITIS 205 0.0378
151 SPINAL PAIN 262 0.0378
152 MICTURITION URGENCY 279 0.0378
153 TASTE DISORDER 173 0.0378
154 BURSITIS 253 0.0377
155 INCREASED TENDENCY TO BRUISE 250 0.0377
156 NEPHROLITHIASIS 1044 0.0376
157 URINARY TRACT INFECTION 3954 0.0376
158 ENTERITIS 137 0.0376
159 CHOLELITHIASIS 891 0.0375
160 MENISCUS INJURY 146 0.0375
161 DRUG LEVEL INCREASED 392 0.0375
162 PANCYTOPENIA 1349 0.0375
163 ESCHERICHIA INFECTION 185 0.0374
164 CHOLECYSTITIS ACUTE 153 0.0374
165 REBOUND EFFECT 173 0.0374
166 LARGE INTESTINE POLYP 176 0.0374
167 GASTROINTESTINAL HAEMORRHAGE 2531 0.0373
168 VITAMIN D DECREASED 218 0.0373
169 SPUTUM DISCOLOURED 214 0.0373
170 CIRCULATORY COLLAPSE 481 0.0372
171 EXOSTOSIS 225 0.0372
172 HAIR COLOUR CHANGES 363 0.0372
173 LEUKOCYTOSIS 450 0.0370
174 RHABDOMYOLYSIS 1080 0.0370
175 ATRIAL FIBRILLATION 2332 0.0369
176 MULTIPLE MYELOMA 172 0.0369
177 ARTERIOSCLEROSIS CORONARY ARTERY 173 0.0368
178 HAEMOGLOBIN DECREASED 2607 0.0368
179 DYSPEPSIA 2355 0.0368
180 ACIDOSIS 198 0.0368
181 HAEMORRHOIDS 502 0.0367
182 SPINAL COLUMN STENOSIS 175 0.0367
183 DIZZINESS POSTURAL 196 0.0367
184 ORAL DISORDER 183 0.0367
185 ANAEMIA 4789 0.0367
186 HYPOVOLAEMIA 152 0.0366
187 CONFUSIONAL STATE 4093 0.0366
188 OSTEOPOROSIS 939 0.0366
189 HEPATOMEGALY 272 0.0366
190 HAEMODIALYSIS 283 0.0365
191 RENAL FAILURE CHRONIC 280 0.0364
192 DYSURIA 932 0.0363
193 MOUTH HAEMORRHAGE 177 0.0363
194 ABNORMAL FAECES 179 0.0363
195 WHITE BLOOD CELL COUNT INCREASED 1005 0.0363
196 PETECHIAE 260 0.0362
197 INCONTINENCE 263 0.0362
198 HAEMOPTYSIS 721 0.0362
199 FOOT DEFORMITY 255 0.0362
200 MUSCULOSKELETAL CHEST PAIN 370 0.0362
201 TROPONIN INCREASED 151 0.0361
202 SEPTIC SHOCK 972 0.0359
203 PULMONARY MASS 317 0.0359
204 RESTLESS LEGS SYNDROME 450 0.0358
205 UPPER-AIRWAY COUGH SYNDROME 166 0.0358
206 ROTATOR CUFF SYNDROME 324 0.0356
207 CARDIOMEGALY 353 0.0355
208 ORAL MUCOSAL BLISTERING 153 0.0355
209 DIVERTICULITIS 636 0.0355
210 CARDIAC FAILURE ACUTE 137 0.0355
211 BLOOD CREATININE INCREASED 1602 0.0354
212 BLADDER DISORDER 241 0.0354
213 ERUCTATION 380 0.0354
214 THYROID DISORDER 343 0.0353
215 DROOLING 154 0.0353
216 FIBROMYALGIA 509 0.0353
217 PSEUDOMONAS INFECTION 178 0.0353
218 ASPIRATION 246 0.0353
219 RIB FRACTURE 473 0.0353
220 DERMATITIS BULLOUS 172 0.0352
221 INTERVERTEBRAL DISC PROTRUSION 551 0.0352
222 COAGULOPATHY 427 0.0351
223 BLOOD ALKALINE PHOSPHATASE INCREASED 681 0.0351
224 PULMONARY FIBROSIS 402 0.0351
225 VIRAL UPPER RESPIRATORY TRACT INFECTION 140 0.0350
226 DERMATITIS EXFOLIATIVE 156 0.0349
227 LETHARGY 1428 0.0349
228 BLOOD PRESSURE DIASTOLIC DECREASED 143 0.0348
229 HYPERCHOLESTEROLAEMIA 196 0.0348
230 DEHYDRATION 3253 0.0348
231 PRODUCTIVE COUGH 945 0.0348
232 COLITIS ISCHAEMIC 161 0.0348
233 SEASONAL ALLERGY 238 0.0347
234 MYOCLONUS 286 0.0347
235 ACUTE CORONARY SYNDROME 220 0.0347
236 PNEUMONITIS 532 0.0346
237 NEURALGIA 509 0.0346
238 GAMMA-GLUTAMYLTRANSFERASE INCREASED 590 0.0346
239 FEELING OF BODY TEMPERATURE CHANGE 142 0.0344
240 NERVE COMPRESSION 203 0.0343
241 PULMONARY THROMBOSIS 218 0.0343
242 GOUT 403 0.0343
243 SWOLLEN TONGUE 770 0.0342
244 FULL BLOOD COUNT DECREASED 378 0.0342
245 DELIRIUM 744 0.0342
246 MUCOSAL INFLAMMATION 578 0.0341
247 LYMPHOEDEMA 140 0.0341
248 ECCHYMOSIS 177 0.0341
249 EMPHYSEMA 251 0.0341
250 DRY MOUTH 1815 0.0341
251 JAUNDICE 711 0.0341
252 SEPSIS 2552 0.0340
253 FLATULENCE 1262 0.0340
254 SENSORY LOSS 189 0.0340
255 SPINAL DISORDER 215 0.0340
256 JOINT EFFUSION 161 0.0339
257 HYPERLIPIDAEMIA 315 0.0339
258 ELECTROCARDIOGRAM ABNORMAL 186 0.0339
259 BLOOD POTASSIUM INCREASED 382 0.0339
260 TORSADE DE POINTES 190 0.0338
261 DIARRHOEA HAEMORRHAGIC 208 0.0338
262 URINARY INCONTINENCE 694 0.0338
263 RED BLOOD CELL COUNT DECREASED 596 0.0336
264 ACUTE PULMONARY OEDEMA 140 0.0336
265 WHEEZING 1080 0.0336
266 FACIAL PARALYSIS 162 0.0335
267 LIGAMENT SPRAIN 201 0.0335
268 CEREBRAL ISCHAEMIA 137 0.0335
269 RESPIRATORY TRACT INFECTION 525 0.0334
270 ATRIOVENTRICULAR BLOCK COMPLETE 153 0.0334
271 ABDOMINAL PAIN 5095 0.0333
272 PERIPHERAL SWELLING 2837 0.0333
273 ULCER 350 0.0332
274 LARGE INTESTINE PERFORATION 156 0.0332
275 HAIR TEXTURE ABNORMAL 362 0.0332
276 HEPATIC CIRRHOSIS 388 0.0331
277 FEEDING DISORDER 313 0.0330
278 HOSPICE CARE 141 0.0330
279 C-REACTIVE PROTEIN INCREASED 706 0.0330
280 BALANCE DISORDER 1965 0.0330
281 CORONARY ARTERY OCCLUSION 363 0.0330
282 LEFT VENTRICULAR DYSFUNCTION 146 0.0329
283 PNEUMONIA 6777 0.0329
284 SCOLIOSIS 136 0.0329
285 SPINAL FRACTURE 404 0.0328
286 GASTROINTESTINAL INFLAMMATION 150 0.0328
287 ACUTE MYOCARDIAL INFARCTION 739 0.0328
288 COLITIS 693 0.0328
289 MITRAL VALVE INCOMPETENCE 268 0.0327
290 CONSTIPATION 4235 0.0327
291 APHAGIA 157 0.0326
292 ONYCHOCLASIS 136 0.0326
293 SPINAL OPERATION 161 0.0326
294 PRESYNCOPE 517 0.0325
295 IMMUNOSUPPRESSION 149 0.0324
296 PROTHROMBIN TIME PROLONGED 167 0.0324
297 PROCTALGIA 137 0.0324
298 DRY THROAT 214 0.0323
299 CELLULITIS 1130 0.0323
300 FALL 7105 0.0323
301 NEPHROTIC SYNDROME 143 0.0322
302 LUNG INFILTRATION 235 0.0322
303 CONTUSION 2000 0.0322
304 ANURIA 212 0.0322
305 ASCITES 638 0.0321
306 PERIPHERAL COLDNESS 299 0.0320
307 PALLOR 550 0.0320
308 PULMONARY HYPERTENSION 484 0.0320
309 ARTERIOSCLEROSIS 212 0.0320
310 MYOPATHY 189 0.0319
311 DECREASED APPETITE 4492 0.0318
312 GALLBLADDER DISORDER 432 0.0318
313 HEPATITIS 552 0.0318
314 HYPOGLYCAEMIA 1114 0.0318
315 HALLUCINATION, VISUAL 405 0.0317
316 SYNCOPE 2207 0.0317
317 BRADYPHRENIA 148 0.0317
318 INCREASED UPPER AIRWAY SECRETION 138 0.0317
319 TENDERNESS 226 0.0317
320 HYPOALBUMINAEMIA 153 0.0317
321 PELVIC FRACTURE 161 0.0316
322 HERNIA 370 0.0316
323 NODULE 259 0.0316
324 PNEUMOTHORAX 316 0.0316
325 RENAL DISORDER 958 0.0316
326 SCIATICA 280 0.0315
327 WRIST FRACTURE 250 0.0315
328 ATAXIA 269 0.0315
329 GLOSSODYNIA 342 0.0315
330 MUSCULOSKELETAL DISCOMFORT 345 0.0314
331 METABOLIC ACIDOSIS 609 0.0314
332 HYPOXIA 690 0.0314
333 PULMONARY CONGESTION 279 0.0314
334 PULMONARY OEDEMA 965 0.0313
335 MUSCLE RIGIDITY 251 0.0313
336 HEAD DISCOMFORT 320 0.0313
337 DIARRHOEA 12275 0.0313
338 ABDOMINAL PAIN UPPER 4151 0.0313
339 JOINT DISLOCATION 212 0.0313
340 BONE DISORDER 436 0.0313
341 URINARY RETENTION 688 0.0312
342 RASH PUSTULAR 187 0.0312
343 PHARYNGITIS 271 0.0312
344 BASAL CELL CARCINOMA 313 0.0312
345 FEBRILE NEUTROPENIA 1195 0.0311
346 POLLAKIURIA 867 0.0311
347 BRONCHITIS 1674 0.0311
348 RIGHT VENTRICULAR FAILURE 170 0.0311
349 AGRANULOCYTOSIS 343 0.0310
350 LUNG INFECTION 490 0.0310
351 BACTERAEMIA 212 0.0310
352 GASTRIC ULCER HAEMORRHAGE 139 0.0310
353 DYSPHONIA 1149 0.0309
354 GINGIVAL PAIN 168 0.0309
355 NEUROPATHY PERIPHERAL 1679 0.0309
356 ARTHRITIS 1515 0.0309
357 HYPERBILIRUBINAEMIA 207 0.0309
358 LIPASE INCREASED 167 0.0308
359 NAIL DISORDER 151 0.0308
360 RESPIRATORY FAILURE 1571 0.0308
361 ARTERIAL OCCLUSIVE DISEASE 182 0.0307
362 VENTRICULAR FIBRILLATION 248 0.0307
363 GINGIVAL BLEEDING 267 0.0307
364 PARKINSONISM 188 0.0306
365 GASTROINTESTINAL INFECTION 168 0.0305
366 NECK PAIN 1128 0.0305
367 LIP SWELLING 683 0.0305
368 OXYGEN SATURATION DECREASED 917 0.0305
369 NIGHT SWEATS 607 0.0304
370 INFARCTION 164 0.0304
371 CHEST PAIN 4023 0.0304
372 FLANK PAIN 189 0.0303
373 HAEMORRHAGIC STROKE 180 0.0303
374 MUSCULAR WEAKNESS 2343 0.0303
375 WEIGHT FLUCTUATION 156 0.0303
376 DISORIENTATION 901 0.0303
377 ECONOMIC PROBLEM 426 0.0302
378 WEIGHT DECREASED 5401 0.0302
379 EPISTAXIS 1570 0.0302
380 HEMIPLEGIA 183 0.0301
381 CATARACT 1065 0.0301
382 BLISTER 1021 0.0300
383 MYOCARDIAL ISCHAEMIA 283 0.0300
384 PLEURAL EFFUSION 1270 0.0300
385 PURPURA 193 0.0299
386 PARAESTHESIA ORAL 272 0.0299
387 GAIT INABILITY 396 0.0299
388 INFLAMMATION 834 0.0299
389 LIMB INJURY 465 0.0299
390 BLOOD PRESSURE ABNORMAL 332 0.0298
391 BLOOD CHOLESTEROL INCREASED 921 0.0298
392 HAEMATOMA 570 0.0298
393 OEDEMA PERIPHERAL 2795 0.0298
394 COUGH 4997 0.0298
395 WOUND INFECTION 172 0.0298
396 CYSTITIS 660 0.0298
397 DYSPHAGIA 1842 0.0298
398 GASTROINTESTINAL PAIN 198 0.0298
399 HICCUPS 157 0.0297
400 BLOOD COUNT ABNORMAL 406 0.0297
401 THROMBOCYTOPENIA 2109 0.0297
402 PLEURISY 137 0.0297
403 SQUAMOUS CELL CARCINOMA 185 0.0297
404 TONGUE DISORDER 164 0.0296
405 HYPOTENSION 3905 0.0296
406 ADRENAL INSUFFICIENCY 168 0.0295
407 ABDOMINAL DISTENSION 1992 0.0295
408 DYSPNOEA 10961 0.0295
409 INCOHERENT 148 0.0295
410 FAECAL INCONTINENCE 142 0.0295
411 APHONIA 251 0.0294
412 BRADYCARDIA 1086 0.0294
413 GENERALISED OEDEMA 238 0.0293
414 SUBDURAL HAEMATOMA 315 0.0293
415 MENTAL STATUS CHANGES 585 0.0293
416 ASTHENIA 7240 0.0292
417 FOOT FRACTURE 373 0.0292
418 DECUBITUS ULCER 170 0.0292
419 LOCALISED INFECTION 449 0.0292
420 ENCEPHALOPATHY 456 0.0292
421 VENTRICULAR EXTRASYSTOLES 223 0.0292
422 HYPERAESTHESIA 176 0.0291
423 TRICUSPID VALVE INCOMPETENCE 160 0.0291
424 ANKLE FRACTURE 301 0.0291
425 INTESTINAL OBSTRUCTION 660 0.0291
426 ALANINE AMINOTRANSFERASE INCREASED 1285 0.0291
427 EOSINOPHILIA 314 0.0290
428 INTERNAL HAEMORRHAGE 232 0.0290
429 BLOOD URINE PRESENT 393 0.0290
430 OROPHARYNGEAL PAIN 1676 0.0290
431 CHOKING 359 0.0290
432 WOUND 380 0.0290
433 BLOOD CREATINE PHOSPHOKINASE INCREASED 653 0.0289
434 GROIN PAIN 179 0.0289
435 MUSCULOSKELETAL PAIN 1302 0.0289
436 AGEUSIA 464 0.0289
437 SALIVARY HYPERSECRETION 190 0.0289
438 RED BLOOD CELL SEDIMENTATION RATE INCREASED 198 0.0289
439 HYPOAESTHESIA ORAL 299 0.0288
440 EATING DISORDER 406 0.0288
441 PLATELET COUNT DECREASED 1898 0.0288
442 IRRITABLE BOWEL SYNDROME 332 0.0288
443 TENDON RUPTURE 267 0.0288
444 SKIN ULCER 498 0.0288
445 TACHYPNOEA 235 0.0288
446 BLOOD BILIRUBIN INCREASED 571 0.0287
447 BACK PAIN 4429 0.0286
448 FURUNCLE 153 0.0286
449 ANGINA UNSTABLE 158 0.0285
450 RASH MACULO-PAPULAR 401 0.0285
451 DECREASED IMMUNE RESPONSIVENESS 139 0.0285
452 ARTHROPATHY 942 0.0284
453 DENTAL CARIES 222 0.0284
454 DRUG-INDUCED LIVER INJURY 403 0.0284
455 MULTI-ORGAN FAILURE 493 0.0284
456 PNEUMONIA ASPIRATION 460 0.0284
457 BACK DISORDER 308 0.0284
458 JOINT RANGE OF MOTION DECREASED 198 0.0284
459 JOINT SWELLING 1966 0.0283
460 TRANSIENT ISCHAEMIC ATTACK 720 0.0283
461 VOMITING 8701 0.0283
462 THIRST 308 0.0283
463 VASCULITIS 208 0.0283
464 HALLUCINATION 1330 0.0283
465 FORMICATION 153 0.0282
466 RETCHING 397 0.0282
467 NERVE INJURY 216 0.0282
468 EAR PAIN 352 0.0282
469 SHOCK HAEMORRHAGIC 147 0.0282
470 TRANSFUSION 201 0.0282
471 HYPOTHERMIA 199 0.0282
472 PLASMA CELL MYELOMA 627 0.0282
473 MADAROSIS 278 0.0281
474 OBESITY 279 0.0281
475 STAPHYLOCOCCAL INFECTION 673 0.0280
476 UNRESPONSIVE TO STIMULI 493 0.0280
477 HYPOKINESIA 275 0.0280
478 SINUS TACHYCARDIA 275 0.0279
479 HYPOTHYROIDISM 526 0.0279
480 ANGINA PECTORIS 602 0.0279
481 GASTROENTERITIS VIRAL 315 0.0279
482 JOINT INJURY 377 0.0279
483 SKIN INFECTION 182 0.0278
484 BACTERIAL INFECTION 310 0.0278
485 HAEMATOCHEZIA 866 0.0278
486 HEPATIC FAILURE 605 0.0278
487 UPPER RESPIRATORY TRACT INFECTION 843 0.0277
488 TENDONITIS 313 0.0277
489 DERMATITIS ALLERGIC 205 0.0277
490 THERAPY INTERRUPTED 153 0.0277
491 SINUSITIS 1802 0.0277
492 STOMATITIS 1009 0.0277
493 CHOLECYSTECTOMY 212 0.0276
494 HYPERTENSION 3776 0.0276
495 BLOOD PRESSURE FLUCTUATION 409 0.0276
496 ARTHRALGIA 6711 0.0275
497 SINUS BRADYCARDIA 187 0.0274
498 MUSCLE DISORDER 166 0.0274
499 PAIN IN EXTREMITY 5561 0.0274
500 SINUS DISORDER 346 0.0274
501 PERICARDIAL EFFUSION 402 0.0274
502 INFLUENZA 1864 0.0273
503 LOCAL SWELLING 477 0.0273
504 LACERATION 257 0.0272
505 MASS 262 0.0272
506 HIP FRACTURE 563 0.0272
507 ERYTHEMA MULTIFORME 178 0.0272
508 OEDEMA 974 0.0271
509 HYPERCALCAEMIA 218 0.0271
510 PULMONARY EMBOLISM 1930 0.0271
511 BONE PAIN 1082 0.0271
512 DEEP VEIN THROMBOSIS 1395 0.0271
513 HYPERTENSIVE CRISIS 213 0.0271
514 COORDINATION ABNORMAL 303 0.0271
515 NEUTROPENIA 1985 0.0271
516 HEAD INJURY 562 0.0270
517 MYALGIA 3160 0.0270
518 VENTRICULAR TACHYCARDIA 308 0.0270
519 PARAESTHESIA 2923 0.0270
520 MUSCLE STRAIN 155 0.0270
521 ILEUS 223 0.0269
522 DYSARTHRIA 720 0.0269
523 BLOOD PRESSURE SYSTOLIC INCREASED 294 0.0269
524 TOXIC SKIN ERUPTION 186 0.0269
525 LUNG DISORDER 824 0.0269
526 MUSCLE SPASMS 3362 0.0269
527 FLUID OVERLOAD 378 0.0269
528 INTESTINAL PERFORATION 203 0.0268
529 ATRIOVENTRICULAR BLOCK 143 0.0268
530 APPENDICITIS 149 0.0268
531 GASTRIC DISORDER 756 0.0268
532 TOOTH ABSCESS 200 0.0268
533 LIMB DISCOMFORT 506 0.0267
534 RESPIRATORY RATE INCREASED 157 0.0267
535 FACIAL PAIN 153 0.0267
536 IMPAIRED HEALING 543 0.0267
537 SKIN CANCER 241 0.0267
538 LYMPHOCYTE COUNT DECREASED 297 0.0267
539 GLAUCOMA 343 0.0266
540 CYST 214 0.0266
541 ORAL DISCOMFORT 256 0.0266
542 APHASIA 563 0.0266
543 LUPUS-LIKE SYNDROME 145 0.0266
544 SWELLING FACE 1178 0.0266
545 SKIN DISCOLOURATION 819 0.0265
546 KNEE ARTHROPLASTY 289 0.0265
547 HEPATOTOXICITY 345 0.0265
548 LARYNGITIS 182 0.0265
549 FREQUENT BOWEL MOVEMENTS 363 0.0265
550 TOOTH FRACTURE 197 0.0264
551 FLUID RETENTION 922 0.0264
552 SEDATION 415 0.0264
553 EAR DISCOMFORT 171 0.0264
554 SINUS CONGESTION 241 0.0264
555 THROAT IRRITATION 735 0.0263
556 HYPERSOMNIA 492 0.0263
557 ISCHAEMIC STROKE 336 0.0263
558 CARDIAC FAILURE 1387 0.0263
559 HYPERHIDROSIS 2369 0.0263
560 NEUTROPHIL COUNT DECREASED 586 0.0263
561 POOR QUALITY SLEEP 343 0.0263
562 BLOOD TRIGLYCERIDES INCREASED 352 0.0263
563 HEMIPARESIS 334 0.0262
564 GAIT DISTURBANCE 3410 0.0262
565 DYSSTASIA 512 0.0262
566 CHEST DISCOMFORT 1689 0.0262
567 SKIN LESION 444 0.0262
568 MUSCLE ATROPHY 204 0.0261
569 TACHYCARDIA 1538 0.0261
570 BLOOD DISORDER 139 0.0261
571 UPPER LIMB FRACTURE 364 0.0261
572 MALIGNANT MELANOMA 234 0.0260
573 RESPIRATORY DISTRESS 511 0.0260
574 PROSTATIC SPECIFIC ANTIGEN INCREASED 232 0.0259
575 PYREXIA 5888 0.0259
576 DIZZINESS 8615 0.0259
577 HIP ARTHROPLASTY 208 0.0259
578 LEUKOPENIA 849 0.0258
579 EYE INFECTION 164 0.0258
580 RASH PRURITIC 867 0.0258
581 TREMOR 3013 0.0257
582 PHOTOSENSITIVITY REACTION 286 0.0257
583 CYANOSIS 291 0.0257
584 HEART RATE IRREGULAR 424 0.0256
585 HYPERGLYCAEMIA 645 0.0256
586 VITREOUS FLOATERS 146 0.0256
587 MEMORY IMPAIRMENT 2308 0.0256
588 RASH ERYTHEMATOUS 692 0.0256
589 LYMPHADENOPATHY 591 0.0255
590 DIABETES MELLITUS INADEQUATE CONTROL 310 0.0255
591 BACK INJURY 164 0.0255
592 BODY TEMPERATURE INCREASED 357 0.0255
593 PHARYNGEAL OEDEMA 380 0.0254
594 HYPERTHERMIA 136 0.0254
595 FEELING DRUNK 142 0.0254
596 VIRAL INFECTION 537 0.0254
597 ABDOMINAL DISCOMFORT 2542 0.0254
598 FATIGUE 12077 0.0254
599 SWELLING 1412 0.0253
600 MALAISE 7832 0.0253
601 SUDDEN DEATH 212 0.0253
602 MACULAR DEGENERATION 180 0.0253
603 FEELING COLD 475 0.0252
604 ACUTE RESPIRATORY DISTRESS SYNDROME 297 0.0252
605 ARRHYTHMIA 856 0.0252
606 COGNITIVE DISORDER 750 0.0252
607 SCHIZOPHRENIA 181 0.0252
608 SPEECH DISORDER 921 0.0252
609 MULTIPLE FRACTURES 177 0.0251
610 TRANSAMINASES INCREASED 378 0.0251
611 SECRETION DISCHARGE 169 0.0251
612 PHOTOPHOBIA 286 0.0251
613 RASH MACULAR 531 0.0250
614 ASPARTATE AMINOTRANSFERASE INCREASED 963 0.0250
615 PRURITUS GENERALISED 544 0.0250
616 MUSCLE TWITCHING 407 0.0250
617 BLOOD TEST ABNORMAL 188 0.0250
618 TOOTH INFECTION 201 0.0250
619 HAEMORRHAGE INTRACRANIAL 294 0.0250
620 LACTIC ACIDOSIS 468 0.0249
621 MOBILITY DECREASED 1101 0.0249
622 DEVICE RELATED INFECTION 285 0.0249
623 ASTHMA 1436 0.0249
624 GASTRIC HAEMORRHAGE 219 0.0248
625 POST PROCEDURAL COMPLICATION 343 0.0248
626 STEVENS-JOHNSON SYNDROME 418 0.0248
627 DIABETES MELLITUS 1350 0.0248
628 DRY EYE 560 0.0248
629 FEELING HOT 1006 0.0247
630 TUBERCULOSIS 205 0.0246
631 LIVER DISORDER 698 0.0246
632 METASTASES TO BONE 223 0.0246
633 DEPRESSION 4108 0.0246
634 BRONCHOSPASM 255 0.0245
635 TINNITUS 764 0.0245
636 CHILLS 1875 0.0245
637 PANCREATITIS 929 0.0245
638 GENERAL PHYSICAL HEALTH DETERIORATION 1575 0.0245
639 CONDITION AGGRAVATED 3864 0.0245
640 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 348 0.0244
641 WHITE BLOOD CELL COUNT DECREASED 1611 0.0244
642 BLOOD PRESSURE INCREASED 2405 0.0244
643 NAUSEA 12652 0.0244
644 TOOTH DISORDER 377 0.0243
645 AORTIC ANEURYSM 142 0.0243
646 LYMPHOPENIA 203 0.0243
647 CEREBRAL HAEMORRHAGE 620 0.0243
648 FISTULA 162 0.0242
649 VERTIGO 1034 0.0242
650 CARDIO-RESPIRATORY ARREST 770 0.0242
651 HEART RATE DECREASED 521 0.0242
652 THROMBOSIS 1290 0.0242
653 SNEEZING 319 0.0242
654 DYSGEUSIA 1256 0.0242
655 SUBARACHNOID HAEMORRHAGE 170 0.0242
656 HYPOAESTHESIA 2458 0.0242
657 OBSTRUCTIVE AIRWAYS DISORDER 150 0.0242
658 VISION BLURRED 2161 0.0241
659 PAIN IN JAW 494 0.0240
660 DEPRESSED MOOD 807 0.0240
661 PAIN 8639 0.0240
662 BURNING SENSATION 1163 0.0240
663 SKIN HAEMORRHAGE 168 0.0240
664 IMMUNE SYSTEM DISORDER 195 0.0240
665 MOTOR DYSFUNCTION 162 0.0240
666 MULTIPLE ORGAN DYSFUNCTION SYNDROME 312 0.0238
667 ACUTE HEPATIC FAILURE 200 0.0238
668 LOSS OF CONSCIOUSNESS 2136 0.0238
669 EAR INFECTION 361 0.0237
670 AGITATION 1300 0.0237
671 BLOOD PRESSURE DECREASED 1042 0.0237
672 LIVER INJURY 250 0.0236
673 DIPLOPIA 407 0.0236
674 FUNGAL INFECTION 506 0.0236
675 SOMNOLENCE 3178 0.0236
676 ANGIOEDEMA 687 0.0235
677 INSOMNIA 4376 0.0235
678 ILLNESS 198 0.0234
679 CARDIAC MURMUR 160 0.0233
680 DERMATITIS 280 0.0233
681 HUNGER 163 0.0233
682 PALPITATIONS 1842 0.0233
683 DELUSION 235 0.0233
684 DYSKINESIA 654 0.0233
685 PARANOIA 295 0.0232
686 NEUROLEPTIC MALIGNANT SYNDROME 197 0.0232
687 BREAST PAIN 184 0.0232
688 DEMENTIA 363 0.0232
689 COLD SWEAT 285 0.0232
690 DEPRESSED LEVEL OF CONSCIOUSNESS 615 0.0232
691 MANIA 279 0.0232
692 HEART RATE INCREASED 1496 0.0231
693 HEPATOCELLULAR INJURY 270 0.0231
694 SLEEP DISORDER 923 0.0230
695 FEMUR FRACTURE 544 0.0230
696 HERPES ZOSTER 855 0.0229
697 ABSCESS 232 0.0229
698 BRAIN OEDEMA 198 0.0229
699 HYPERTHYROIDISM 206 0.0229
700 CARDIOMYOPATHY 242 0.0228
701 SEIZURE 1411 0.0228
702 RHINORRHOEA 873 0.0228
703 GASTROINTESTINAL DISORDER 1040 0.0228
704 CONJUNCTIVITIS 221 0.0228
705 JOINT STIFFNESS 391 0.0227
706 BEDRIDDEN 202 0.0227
707 ACTIVITIES OF DAILY LIVING IMPAIRED 451 0.0227
708 BLOOD LACTATE DEHYDROGENASE INCREASED 277 0.0227
709 INFECTION 1925 0.0226
710 THERAPY CESSATION 698 0.0226
711 BODY TEMPERATURE DECREASED 145 0.0225
712 NERVOUSNESS 902 0.0225
713 METASTASES TO LIVER 243 0.0225
714 THROAT TIGHTNESS 408 0.0225
715 FACE OEDEMA 274 0.0224
716 MUSCULOSKELETAL STIFFNESS 1225 0.0224
717 PRURITUS 4684 0.0224
718 AMNESIA 1062 0.0224
719 RESTLESSNESS 572 0.0224
720 EJECTION FRACTION DECREASED 213 0.0224
721 MOVEMENT DISORDER 496 0.0224
722 ECZEMA 347 0.0224
723 ABASIA 554 0.0224
724 COELIAC DISEASE 146 0.0224
725 ANHEDONIA 415 0.0224
726 HOT FLUSH 992 0.0223
727 RHEUMATOID ARTHRITIS 1495 0.0223
728 LOWER LIMB FRACTURE 249 0.0223
729 LIVER FUNCTION TEST INCREASED 239 0.0222
730 ANXIETY 4314 0.0221
731 SENSORY DISTURBANCE 270 0.0220
732 OSTEOMYELITIS 297 0.0220
733 CORONARY ARTERY DISEASE 572 0.0220
734 NASAL CONGESTION 744 0.0220
735 RESPIRATORY TRACT CONGESTION 226 0.0219
736 NIGHTMARE 555 0.0219
737 ACUTE MYELOID LEUKAEMIA 219 0.0218
738 HEADACHE 9087 0.0218
739 TOOTHACHE 265 0.0218
740 DISTURBANCE IN ATTENTION 831 0.0218
741 SLUGGISHNESS 150 0.0217
742 FLUSHING 1666 0.0217
743 METASTASES TO LUNG 150 0.0217
744 POLYNEUROPATHY 147 0.0217
745 HALLUCINATION, AUDITORY 230 0.0217
746 CARDIAC ARREST 1291 0.0216
747 DISSEMINATED INTRAVASCULAR COAGULATION 230 0.0216
748 CARDIOGENIC SHOCK 178 0.0216
749 HYPOTONIA 161 0.0216
750 DISEASE PROGRESSION 1396 0.0216
751 METASTASES TO CENTRAL NERVOUS SYSTEM 158 0.0216
752 PSORIATIC ARTHROPATHY 394 0.0215
753 THINKING ABNORMAL 304 0.0215
754 WEIGHT INCREASED 3077 0.0215
755 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 313 0.0215
756 COVID-19 264 0.0215
757 ANAPHYLACTIC REACTION 695 0.0214
758 CARDIAC FAILURE CONGESTIVE 1465 0.0214
759 PULMONARY ARTERIAL HYPERTENSION 229 0.0213
760 LABORATORY TEST ABNORMAL 397 0.0213
761 HEPATIC FUNCTION ABNORMAL 480 0.0213
762 SKIN FISSURES 173 0.0212
763 DEAFNESS 350 0.0212
764 INTERSTITIAL LUNG DISEASE 633 0.0212
765 MENTAL IMPAIRMENT 353 0.0211
766 STRESS 925 0.0211
767 ALOPECIA 2806 0.0211
768 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 389 0.0211
769 RESPIRATORY DISORDER 420 0.0211
770 RASH GENERALISED 548 0.0210
771 INTENTIONAL PRODUCT USE ISSUE 800 0.0210
772 HEPATIC ENZYME INCREASED 835 0.0210
773 MYELODYSPLASTIC SYNDROME 213 0.0209
774 NASOPHARYNGITIS 2372 0.0209
775 LACRIMATION INCREASED 354 0.0208
776 VISUAL IMPAIRMENT 1498 0.0207
777 TYPE 2 DIABETES MELLITUS 486 0.0207
778 MIDDLE INSOMNIA 247 0.0207
779 RASH PAPULAR 340 0.0206
780 CROHN'S DISEASE 141 0.0206
781 BIPOLAR DISORDER 170 0.0205
782 PERITONITIS 318 0.0205
783 ORAL HERPES 229 0.0204
784 GASTRIC CANCER 153 0.0203
785 TREATMENT NONCOMPLIANCE 640 0.0203
786 SYSTEMIC LUPUS ERYTHEMATOSUS 312 0.0202
787 HYPOACUSIS 467 0.0201
788 INCREASED APPETITE 224 0.0201
789 PRODUCT DOSE OMISSION 1378 0.0200
790 LUNG NEOPLASM MALIGNANT 394 0.0200
791 INFUSION RELATED REACTION 650 0.0200
792 DRUG ERUPTION 217 0.0199
793 SCAB 144 0.0199
794 FEELING ABNORMAL 3352 0.0198
795 WITHDRAWAL SYNDROME 518 0.0198
796 BLINDNESS UNILATERAL 188 0.0197
797 DISEASE RECURRENCE 298 0.0197
798 POST PROCEDURAL HAEMORRHAGE 169 0.0196
799 EYE HAEMORRHAGE 184 0.0196
800 MIGRAINE 1127 0.0196
801 PSYCHOTIC DISORDER 411 0.0196
802 DISCOMFORT 591 0.0196
803 EPILEPSY 364 0.0195
804 SKIN DISORDER 377 0.0195
805 APATHY 193 0.0194
806 DERMATITIS CONTACT 139 0.0194
807 MUSCLE TIGHTNESS 220 0.0194
808 SCAR 232 0.0193
809 RASH 5041 0.0193
810 PRODUCT SUBSTITUTION ISSUE 770 0.0193
811 NEUROTOXICITY 182 0.0193
812 PARALYSIS 191 0.0192
813 COLITIS ULCERATIVE 364 0.0191
814 PANIC ATTACK 486 0.0191
815 MUSCULOSKELETAL DISORDER 254 0.0191
816 COLON CANCER 174 0.0190
817 EYE PAIN 597 0.0190
818 EYE DISORDER 388 0.0189
819 GRAND MAL CONVULSION 174 0.0188
820 HAEMORRHAGE 1270 0.0188
821 ROAD TRAFFIC ACCIDENT 539 0.0188
822 ANOREXIA 241 0.0187
823 CONTRAINDICATED PRODUCT ADMINISTERED 255 0.0186
824 SHOCK 278 0.0186
825 SKIN EXFOLIATION 922 0.0185
826 FEELING JITTERY 265 0.0185
827 THERAPEUTIC RESPONSE UNEXPECTED 575 0.0185
828 PRODUCT TASTE ABNORMAL 151 0.0185
829 ALTERED STATE OF CONSCIOUSNESS 242 0.0184
830 ABDOMINAL PAIN LOWER 329 0.0184
831 ILL-DEFINED DISORDER 456 0.0184
832 SURGERY 577 0.0184
833 PRESCRIBED UNDERDOSE 202 0.0184
834 TOOTH EXTRACTION 160 0.0183
835 INTENTIONAL PRODUCT MISUSE 1019 0.0183
836 EYELID OEDEMA 178 0.0183
837 PROCEDURAL PAIN 311 0.0181
838 PRODUCT PRESCRIBING ERROR 153 0.0181
839 INTENTIONAL SELF-INJURY 257 0.0181
840 QUALITY OF LIFE DECREASED 163 0.0180
841 PRODUCT DOSE OMISSION ISSUE 460 0.0179
842 ABNORMAL DREAMS 398 0.0178
843 CYTOMEGALOVIRUS INFECTION 189 0.0178
844 EMOTIONAL DISTRESS 913 0.0177
845 EYE SWELLING 428 0.0177
846 SUICIDAL IDEATION 1150 0.0176
847 ERYTHEMA 2412 0.0176
848 OSTEONECROSIS OF JAW 347 0.0176
849 BLOOD GLUCOSE FLUCTUATION 140 0.0176
850 INFLUENZA LIKE ILLNESS 1088 0.0175
851 GLYCOSYLATED HAEMOGLOBIN INCREASED 268 0.0175
852 MENTAL DISORDER 482 0.0175
853 NEOPLASM PROGRESSION 340 0.0174
854 NO THERAPEUTIC RESPONSE 212 0.0174
855 BLINDNESS 439 0.0173
856 HEPATITIS C 179 0.0173
857 DIABETIC KETOACIDOSIS 278 0.0172
858 VISUAL ACUITY REDUCED 490 0.0172
859 CARDIAC DISORDER 1106 0.0172
860 COMA 571 0.0172
861 PSYCHOMOTOR HYPERACTIVITY 217 0.0171
862 PROSTATE CANCER 287 0.0170
863 HYPERSENSITIVITY 2020 0.0169
864 DISABILITY 181 0.0169
865 DRUG DOSE OMISSION 2807 0.0169
866 CEREBROVASCULAR ACCIDENT 2118 0.0169
867 TOXICITY TO VARIOUS AGENTS 1732 0.0168
868 URTICARIA 1760 0.0168
869 IMPAIRED DRIVING ABILITY 142 0.0168
870 BLOOD GLUCOSE ABNORMAL 201 0.0167
871 PRESCRIBED OVERDOSE 209 0.0166
872 PSORIASIS 1334 0.0165
873 PANCREATIC CARCINOMA 192 0.0164
874 AGGRESSION 620 0.0163
875 MALIGNANT NEOPLASM PROGRESSION 945 0.0162
876 ERECTILE DYSFUNCTION 271 0.0162
877 EMOTIONAL DISORDER 365 0.0161
878 FRACTURE 225 0.0160
879 ABNORMAL BEHAVIOUR 518 0.0160
880 CEREBRAL INFARCTION 281 0.0160
881 UNEVALUABLE EVENT 848 0.0159
882 GENERALISED TONIC-CLONIC SEIZURE 148 0.0159
883 TOOTH LOSS 196 0.0159
884 MOOD ALTERED 300 0.0159
885 CONVULSION 904 0.0158
886 IRRITABILITY 713 0.0158
887 FEAR 342 0.0157
888 CRYING 431 0.0154
889 LYMPHOMA 146 0.0154
890 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 1096 0.0153
891 INTENTIONAL DRUG MISUSE 322 0.0153
892 DRUG PRESCRIBING ERROR 294 0.0152
893 BONE DENSITY DECREASED 276 0.0152
894 BONE MARROW FAILURE 270 0.0152
895 INCORRECT DOSE ADMINISTERED 1560 0.0152
896 DRUG INTOLERANCE 814 0.0151
897 MOOD SWINGS 363 0.0150
898 DRUG TOXICITY 204 0.0150
899 OFF LABEL USE 5663 0.0149
900 PRODUCT USE ISSUE 1571 0.0149
901 PRODUCT PHYSICAL ISSUE 171 0.0148
902 INJECTION SITE MASS 322 0.0148
903 WRONG TECHNIQUE IN DRUG USAGE PROCESS 535 0.0147
904 MYOCARDIAL INFARCTION 2108 0.0146
905 EYE PRURITUS 236 0.0145
906 OCULAR HYPERAEMIA 384 0.0145
907 BLOOD GLUCOSE DECREASED 512 0.0144
908 PRODUCT USE IN UNAPPROVED INDICATION 1451 0.0143
909 DRUG EFFECT INCOMPLETE 522 0.0142
910 DRY SKIN 1070 0.0141
911 INJURY 763 0.0141
912 BLOOD GLUCOSE INCREASED 1918 0.0141
913 RENAL CANCER 174 0.0140
914 PELVIC PAIN 185 0.0140
915 NEOPLASM MALIGNANT 486 0.0140
916 CENTRAL NERVOUS SYSTEM LESION 151 0.0140
917 HOSPITALISATION 1107 0.0140
918 ANAPHYLACTIC SHOCK 221 0.0138
919 INJECTION SITE PRURITUS 621 0.0138
920 DEVICE MALFUNCTION 441 0.0138
921 ADVERSE DRUG REACTION 618 0.0136
922 ANGER 347 0.0135
923 INJECTION SITE HAEMORRHAGE 630 0.0135
924 MULTIPLE SCLEROSIS RELAPSE 686 0.0135
925 INJECTION SITE PAIN 2401 0.0134
926 DRUG EFFECT DECREASED 728 0.0134
927 EYE IRRITATION 402 0.0134
928 RESPIRATORY ARREST 301 0.0133
929 THERAPEUTIC RESPONSE DECREASED 503 0.0133
930 INCORRECT DRUG ADMINISTRATION DURATION 372 0.0132
931 INTENTIONAL OVERDOSE 519 0.0131
932 CARDIOVASCULAR DISORDER 280 0.0130
933 DRUG INEFFECTIVE 10575 0.0130
934 INJECTION SITE BRUISING 648 0.0129
935 ACCIDENTAL OVERDOSE 299 0.0129
936 INJECTION SITE RASH 234 0.0128
937 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 290 0.0128
938 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 355 0.0128
939 COMPLETED SUICIDE 803 0.0127
940 SUICIDE ATTEMPT 525 0.0126
941 MEDICATION ERROR 491 0.0126
942 IMPAIRED WORK ABILITY 198 0.0125
943 OSTEONECROSIS 287 0.0125
944 DRUG HYPERSENSITIVITY 1684 0.0123
945 INJECTION SITE HAEMATOMA 164 0.0123
946 INJECTION SITE URTICARIA 173 0.0122
947 DRUG DISPENSING ERROR 186 0.0121
948 EXPIRED PRODUCT ADMINISTERED 259 0.0121
949 EXTRA DOSE ADMINISTERED 194 0.0121
950 PRODUCT QUALITY ISSUE 1334 0.0121
951 DRUG ADMINISTRATION ERROR 367 0.0119
952 DEVICE ISSUE 489 0.0119
953 NERVOUS SYSTEM DISORDER 291 0.0118
954 DRUG WITHDRAWAL SYNDROME 551 0.0118
955 INJECTION SITE ERYTHEMA 1019 0.0118
956 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 587 0.0118
957 THERAPY NON-RESPONDER 220 0.0116
958 PAIN OF SKIN 212 0.0115
959 DYSTONIA 173 0.0113
960 UNDERDOSE 526 0.0110
961 INJECTION SITE SWELLING 513 0.0109
962 EXPOSURE DURING PREGNANCY 390 0.0109
963 CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR 147 0.0108
964 OVERDOSE 1284 0.0107
965 BREAST CANCER 406 0.0106
966 DEATH 5620 0.0106
967 EXTRAPYRAMIDAL DISORDER 224 0.0104
968 ADVERSE EVENT 650 0.0104
969 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 986 0.0101
970 INJECTION SITE REACTION 476 0.0100
971 MULTIPLE SCLEROSIS 316 0.0100
972 THERAPEUTIC PRODUCT EFFECT DECREASED 144 0.0097
973 INJECTION SITE WARMTH 156 0.0097
974 PREMATURE BABY 196 0.0096
975 TARDIVE DYSKINESIA 225 0.0093
976 APPLICATION SITE PRURITUS 149 0.0090
977 APPLICATION SITE PAIN 146 0.0089
978 PHARMACEUTICAL PRODUCT COMPLAINT 232 0.0089
979 VAGINAL HAEMORRHAGE 298 0.0089
980 APPLICATION SITE ERYTHEMA 190 0.0088
981 PRODUCT ADHESION ISSUE 176 0.0087
982 FOETAL EXPOSURE DURING PREGNANCY 405 0.0085
983 PRODUCT STORAGE ERROR 179 0.0081
984 SKIN BURNING SENSATION 389 0.0077
985 BLADDER CANCER 156 0.0075
986 INCORRECT ROUTE OF DRUG ADMINISTRATION 263 0.0073
987 MATERNAL EXPOSURE DURING PREGNANCY 298 0.0073
988 DRUG DEPENDENCE 360 0.0068
989 ACNE 365 0.0068
990 NO ADVERSE EVENT 525 0.0063
991 TREATMENT FAILURE 279 0.0061
992 DRUG ABUSE 309 0.0060
993 SKIN IRRITATION 185 0.0058
994 DEVICE DISLOCATION 152 0.0053
995 ACCIDENTAL EXPOSURE TO PRODUCT 177 0.0049
996 DRUG EXPOSURE DURING PREGNANCY 149 0.0044