| # | Side effect | Count |
|---|---|---|
| 0 | DRUG INEFFECTIVE | 52840 |
| 1 | OFF LABEL USE | 37463 |
| 2 | FATIGUE | 31656 |
| 3 | PAIN | 30290 |
| 4 | DYSPNOEA | 27265 |
| 5 | ARTHRALGIA | 26655 |
| 6 | NAUSEA | 22163 |
| 7 | DIARRHOEA | 21584 |
| 8 | CONDITION AGGRAVATED | 21058 |
| 9 | RHEUMATOID ARTHRITIS | 20386 |
| # | Side effect | Count | Frequency |
|---|---|---|---|
| 0 | SWOLLEN JOINT COUNT INCREASED | 991 | 0.8708 |
| 1 | ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE | 3389 | 0.8479 |
| 2 | PEMPHIGUS | 6395 | 0.7846 |
| 3 | RHEUMATIC FEVER | 1133 | 0.7391 |
| 4 | DUODENAL ULCER PERFORATION | 2413 | 0.6557 |
| 5 | RHEUMATOID FACTOR POSITIVE | 2307 | 0.6462 |
| 6 | DEEP VEIN THROMBOSIS POSTOPERATIVE | 325 | 0.6238 |
| 7 | GRANULOMA SKIN | 427 | 0.5939 |
| 8 | HAND DEFORMITY | 5352 | 0.5888 |
| 9 | BLOOD PRESSURE DIASTOLIC ABNORMAL | 1146 | 0.5539 |