SEBELIPASE ALFA

SEBELIPASE ALFA was reported 397 times

SEBELIPASE ALFA is most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 LYSOSOMAL ACID LIPASE DEFICIENCY 2 0.2857
1 INTESTINAL STEATOSIS 1 0.1429
2 ADRENAL CALCIFICATION 1 0.1250
3 HEPATIC STEATO-FIBROSIS 1 0.1111
4 FREE FATTY ACIDS INCREASED 1 0.0833
5 TRANSAMINASES DECREASED 3 0.0625
6 CD4 LYMPHOCYTE PERCENTAGE DECREASED 1 0.0500
7 PROCALCITONIN ABNORMAL 1 0.0435
8 SPLEEN ATROPHY 1 0.0385
9 LIPIDS DECREASED 2 0.0364
10 SUPRAVALVULAR AORTIC STENOSIS 1 0.0357
11 FATTY ACID DEFICIENCY 1 0.0256
12 ANTI-TRANSGLUTAMINASE ANTIBODY INCREASED 1 0.0244
13 LIPIDOSIS 1 0.0244
14 CHITOTRIOSIDASE INCREASED 1 0.0204
15 ENZYME LEVEL DECREASED 1 0.0182
16 PORTAL TRACT INFLAMMATION 1 0.0154
17 NON-HIGH-DENSITY LIPOPROTEIN CHOLESTEROL INCREASED 2 0.0150
18 EXPOSURE TO SARS-COV-2 1 0.0135
19 SALMONELLA BACTERAEMIA 1 0.0128
20 INFANTILE VOMITING 1 0.0125
21 POLYMERASE CHAIN REACTION 1 0.0118
22 ADRENOMEGALY 1 0.0093
23 HYPOTHERMIA NEONATAL 1 0.0089
24 BASOPHIL COUNT DECREASED 1 0.0072
25 CD8 LYMPHOCYTES DECREASED 1 0.0070
26 PORTAL FIBROSIS 1 0.0068
27 WEIGHT DECREASE NEONATAL 1 0.0067
28 POOR WEIGHT GAIN NEONATAL 1 0.0066
29 ADMINISTRATION SITE ERYTHEMA 1 0.0065
30 LICE INFESTATION 1 0.0065
31 REFRACTORY CYTOPENIA WITH UNILINEAGE DYSPLASIA 1 0.0060
32 VIRAL DIARRHOEA 1 0.0052
33 FEEDING INTOLERANCE 1 0.0052
34 LIPIDS INCREASED 6 0.0049
35 GASTROENTERITIS ESCHERICHIA COLI 1 0.0047
36 ANTITHROMBIN III DECREASED 1 0.0047
37 ABDOMINAL LYMPHADENOPATHY 2 0.0047
38 GRANULOCYTE COUNT INCREASED 1 0.0046
39 BLOOD TRIGLYCERIDES DECREASED 1 0.0044
40 VEIN RUPTURE 3 0.0043
41 HEPATIC ENZYME DECREASED 1 0.0043
42 SPERM CONCENTRATION DECREASED 1 0.0043
43 CENTRAL VENOUS CATHETER REMOVAL 1 0.0041
44 DARK CIRCLES UNDER EYES 4 0.0041
45 INFUSION SITE URTICARIA 1 0.0040
46 WEIGHT GAIN POOR 5 0.0036
47 LOW DENSITY LIPOPROTEIN INCREASED 18 0.0036
48 NEURODEVELOPMENTAL DISORDER 1 0.0036
49 RESPIRATORY TRACT INFECTION BACTERIAL 1 0.0036
50 NEUTRALISING ANTIBODIES POSITIVE 1 0.0035
51 HIGH DENSITY LIPOPROTEIN DECREASED 8 0.0030
52 ROTAVIRUS INFECTION 1 0.0030
53 TONGUE ERYTHEMA 1 0.0029
54 HEPATIC ATROPHY 1 0.0029
55 ENTEROVIRUS INFECTION 1 0.0028
56 BODY FAT DISORDER 1 0.0028
57 TRANSAMINASES ABNORMAL 1 0.0027
58 MOTOR DEVELOPMENTAL DELAY 1 0.0027
59 POOR VENOUS ACCESS 12 0.0027
60 RESPIRATORY SYNCYTIAL VIRUS TEST POSITIVE 1 0.0026
61 MEDICAL DEVICE SITE DISCOMFORT 1 0.0026
62 SPEECH DISORDER DEVELOPMENTAL 3 0.0025
63 NUTRITIONAL CONDITION ABNORMAL 1 0.0024
64 PARACENTESIS 1 0.0024
65 SYSTEMIC INFECTION 1 0.0023
66 LOW DENSITY LIPOPROTEIN DECREASED 2 0.0023
67 ANTIBODY TEST POSITIVE 3 0.0023
68 KLEBSIELLA BACTERAEMIA 1 0.0023
69 GRUNTING 1 0.0022
70 DRUG SPECIFIC ANTIBODY PRESENT 7 0.0022
71 HEAT EXHAUSTION 1 0.0022
72 RHINOVIRUS INFECTION 3 0.0021
73 THROAT CLEARING 1 0.0019
74 INFECTIOUS MONONUCLEOSIS 3 0.0019
75 HEPATITIS VIRAL 1 0.0018
76 PALLIATIVE CARE 1 0.0018
77 INJECTION RELATED REACTION 1 0.0018
78 CATHETER SITE SWELLING 1 0.0018
79 CYTOMEGALOVIRUS TEST POSITIVE 2 0.0018
80 SELECTIVE EATING DISORDER 1 0.0017
81 POST PROCEDURAL SWELLING 1 0.0017
82 BLOOD CHOLESTEROL DECREASED 2 0.0017
83 INFUSION SITE REACTION 2 0.0016
84 DACRYOSTENOSIS ACQUIRED 1 0.0016
85 ARNOLD-CHIARI MALFORMATION 1 0.0016
86 CENTRAL VENOUS CATHETERISATION 3 0.0016
87 BLOOD FIBRINOGEN DECREASED 1 0.0016
88 INFUSION SITE RASH 1 0.0016
89 GLOMERULONEPHRITIS MEMBRANOUS 1 0.0015
90 HIGH DENSITY LIPOPROTEIN INCREASED 1 0.0015
91 CARDIAC ANEURYSM 1 0.0014
92 KLEBSIELLA SEPSIS 1 0.0014
93 ANAEMIA OF CHRONIC DISEASE 1 0.0014
94 LIMB MALFORMATION 1 0.0014
95 HYPOPERFUSION 1 0.0014
96 SKIN TEST POSITIVE 1 0.0014
97 EOSINOPHIL COUNT DECREASED 1 0.0012
98 LIP DISCOLOURATION 1 0.0012
99 PARAINFLUENZAE VIRUS INFECTION 1 0.0012
100 BILIRUBIN CONJUGATED INCREASED 2 0.0012
101 DEVICE INFUSION ISSUE 1 0.0011
102 BLOOD IMMUNOGLOBULIN G DECREASED 1 0.0011
103 HEPATOSPLENOMEGALY 2 0.0011
104 BLOOD CREATININE DECREASED 2 0.0010
105 VASCULAR DEVICE INFECTION 1 0.0010
106 RESPIRATORY SYMPTOM 1 0.0010
107 STRIDOR 2 0.0010
108 GASTROENTERITIS NOROVIRUS 1 0.0010
109 DYSLIPIDAEMIA 3 0.0010
110 HEPATOMEGALY 7 0.0010
111 WEIGHT ABNORMAL 1 0.0009
112 CLOSTRIDIUM TEST POSITIVE 1 0.0009
113 FUNCTIONAL GASTROINTESTINAL DISORDER 2 0.0009
114 ACUTE ABDOMEN 1 0.0009
115 SKULL FRACTURE 1 0.0009
116 HEPATIC FIBROSIS 2 0.0009
117 RESPIRATORY TRACT INFECTION VIRAL 1 0.0009
118 PNEUMOPERITONEUM 1 0.0008
119 HYPERAEMIA 1 0.0008
120 AUTISM SPECTRUM DISORDER 1 0.0008
121 FAILURE TO THRIVE 3 0.0008
122 HAEMATOCRIT INCREASED 1 0.0008
123 OROPHARYNGEAL BLISTERING 1 0.0008
124 BLOOD IMMUNOGLOBULIN E INCREASED 1 0.0008
125 PROTEIN TOTAL DECREASED 2 0.0008
126 BLOOD TRIGLYCERIDES INCREASED 10 0.0007
127 CATHETER SITE ERYTHEMA 1 0.0007
128 TRANSPLANT 1 0.0007
129 ADENOVIRUS INFECTION 1 0.0007
130 HEPATIC ENZYME ABNORMAL 2 0.0007
131 RETINAL TEAR 1 0.0007
132 ATRIAL THROMBOSIS 1 0.0007
133 BLOOD PH DECREASED 1 0.0006
134 PHARYNGEAL ERYTHEMA 1 0.0006
135 HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS 1 0.0006
136 TACHYPNOEA 5 0.0006
137 RED BLOOD CELL COUNT INCREASED 1 0.0006
138 INFUSION SITE EXTRAVASATION 2 0.0006
139 INJECTION SITE SCAR 1 0.0006
140 LIVER FUNCTION TEST INCREASED 6 0.0006
141 PSYCHOMOTOR SKILLS IMPAIRED 1 0.0006
142 MALABSORPTION 2 0.0006
143 PAINFUL RESPIRATION 1 0.0006
144 ADRENAL INSUFFICIENCY 3 0.0005
145 INFUSION SITE PAIN 3 0.0005
146 BLOOD SODIUM INCREASED 1 0.0005
147 ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED 2 0.0005
148 INCORRECT DRUG ADMINISTRATION RATE 1 0.0005
149 BLOOD CHOLESTEROL INCREASED 15 0.0005
150 GROWTH RETARDATION 1 0.0005
151 INFLAMMATORY MARKER INCREASED 1 0.0005
152 CONJUNCTIVAL HYPERAEMIA 1 0.0004
153 GASTRIC INFECTION 1 0.0004
154 CARDIAC MURMUR 3 0.0004
155 MALNUTRITION 3 0.0004
156 INFUSION SITE SWELLING 1 0.0004
157 HAEMOGLOBIN INCREASED 1 0.0004
158 BRONCHIOLITIS 1 0.0004
159 HYPOALBUMINAEMIA 2 0.0004
160 AORTIC STENOSIS 1 0.0004
161 MULTIPLE ORGAN DYSFUNCTION SYNDROME 5 0.0004
162 BLOOD BILIRUBIN INCREASED 8 0.0004
163 SENSITIVE SKIN 1 0.0004
164 RHINITIS ALLERGIC 1 0.0004
165 CATHETER SITE INFECTION 1 0.0004
166 INFUSION RELATED REACTION 12 0.0004
167 EXTRASYSTOLES 2 0.0004
168 SPLENOMEGALY 3 0.0004
169 GASTROINTESTINAL INFECTION 2 0.0004
170 HAEMOLYSIS 2 0.0004
171 KLEBSIELLA INFECTION 1 0.0004
172 SYSTEMIC INFLAMMATORY RESPONSE SYNDROME 1 0.0004
173 GASTROENTERITIS VIRAL 4 0.0004
174 DEVICE RELATED INFECTION 4 0.0004
175 MUSCLE STRAIN 2 0.0004
176 INABILITY TO AFFORD MEDICATION 1 0.0003
177 THROMBOSIS IN DEVICE 1 0.0003
178 VIRAL INFECTION 7 0.0003
179 DEVELOPMENTAL DELAY 1 0.0003
180 HISTIOCYTOSIS HAEMATOPHAGIC 1 0.0003
181 SARCOIDOSIS 1 0.0003
182 BLOOD LACTIC ACID INCREASED 1 0.0003
183 HEART RATE ABNORMAL 1 0.0003
184 ERYTHEMA OF EYELID 1 0.0003
185 OCULAR ICTERUS 1 0.0003
186 PHARYNGITIS STREPTOCOCCAL 2 0.0003
187 FOOD ALLERGY 1 0.0003
188 NUCLEAR MAGNETIC RESONANCE IMAGING ABNORMAL 1 0.0003
189 TONGUE DISCOLOURATION 1 0.0003
190 SERUM FERRITIN INCREASED 1 0.0003
191 LABORATORY TEST ABNORMAL 5 0.0003
192 NEUROLOGICAL SYMPTOM 1 0.0003
193 STAPHYLOCOCCAL SEPSIS 1 0.0003
194 INTERNATIONAL NORMALISED RATIO DECREASED 1 0.0003
195 ODYNOPHAGIA 1 0.0003
196 GENERAL PHYSICAL CONDITION ABNORMAL 1 0.0003
197 PIGMENTATION DISORDER 1 0.0003
198 HEPATIC ENZYME INCREASED 10 0.0003
199 ASCITES 5 0.0003
200 VIRAL UPPER RESPIRATORY TRACT INFECTION 1 0.0003
201 ANAPHYLACTIC REACTION 8 0.0003
202 CYTOPENIA 1 0.0002
203 EAR PAIN 3 0.0002
204 PRODUCT PACKAGING QUANTITY ISSUE 1 0.0002
205 DERMATITIS ATOPIC 1 0.0002
206 HYPERVENTILATION 1 0.0002
207 ADVERSE REACTION 2 0.0002
208 OLIGURIA 1 0.0002
209 NEPHROTIC SYNDROME 1 0.0002
210 GASTROINTESTINAL INFLAMMATION 1 0.0002
211 FEEDING DISORDER 2 0.0002
212 CONJUNCTIVITIS 2 0.0002
213 POST PROCEDURAL INFECTION 1 0.0002
214 ILL-DEFINED DISORDER 5 0.0002
215 SKIN LACERATION 1 0.0002
216 TRANSAMINASES INCREASED 3 0.0002
217 WEIGHT FLUCTUATION 1 0.0002
218 HYPOGLYCAEMIA 7 0.0002
219 PRODUCT PACKAGING ISSUE 1 0.0002
220 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 1 0.0002
221 PROTHROMBIN TIME PROLONGED 1 0.0002
222 C-REACTIVE PROTEIN INCREASED 4 0.0002
223 EOSINOPHILIA 2 0.0002
224 HYPERTHERMIA 1 0.0002
225 PRE-EXISTING CONDITION IMPROVED 1 0.0002
226 LYMPHOCYTE COUNT DECREASED 2 0.0002
227 HEPATIC FAILURE 4 0.0002
228 ABDOMINAL DISTENSION 12 0.0002
229 LIP SWELLING 4 0.0002
230 PYREXIA 40 0.0002
231 DECREASED ACTIVITY 1 0.0002
232 DECUBITUS ULCER 1 0.0002
233 BLOOD ALBUMIN DECREASED 1 0.0002
234 APNOEA 1 0.0002
235 PRODUCT ADMINISTRATION ERROR 1 0.0002
236 DEPENDENCE 1 0.0002
237 CLOSTRIDIUM DIFFICILE INFECTION 2 0.0002
238 CHOLESTASIS 2 0.0002
239 DIARRHOEA HAEMORRHAGIC 1 0.0002
240 BLOOD SODIUM DECREASED 2 0.0002
241 IRON DEFICIENCY ANAEMIA 1 0.0002
242 ALANINE AMINOTRANSFERASE INCREASED 7 0.0002
243 EAR DISCOMFORT 1 0.0002
244 ASPARTATE AMINOTRANSFERASE INCREASED 6 0.0002
245 PRODUCT PREPARATION ERROR 1 0.0002
246 HEPATIC ENCEPHALOPATHY 1 0.0002
247 BACTERAEMIA 1 0.0002
248 SLUGGISHNESS 1 0.0001
249 BODY TEMPERATURE INCREASED 2 0.0001
250 CLOSTRIDIUM DIFFICILE COLITIS 1 0.0001
251 LIVER DISORDER 4 0.0001
252 TENDERNESS 1 0.0001
253 BLOOD TEST ABNORMAL 1 0.0001
254 HYPOTONIA 1 0.0001
255 EAR INFECTION 2 0.0001
256 IRRITABILITY 6 0.0001
257 VENTRICULAR EXTRASYSTOLES 1 0.0001
258 RESPIRATORY TRACT INFECTION 2 0.0001
259 ANAPHYLACTIC SHOCK 2 0.0001
260 PLATELET COUNT INCREASED 1 0.0001
261 RESPIRATORY FAILURE 6 0.0001
262 INCORRECT DOSE ADMINISTERED 12 0.0001
263 OSTEOPENIA 1 0.0001
264 GAMMA-GLUTAMYLTRANSFERASE INCREASED 2 0.0001
265 URTICARIA 12 0.0001
266 RED BLOOD CELL COUNT DECREASED 2 0.0001
267 BEDRIDDEN 1 0.0001
268 MYDRIASIS 1 0.0001
269 ROTATOR CUFF SYNDROME 1 0.0001
270 SINUS CONGESTION 1 0.0001
271 PERIPHERAL COLDNESS 1 0.0001
272 MASS 1 0.0001
273 THYROID DISORDER 1 0.0001
274 ANGIOEDEMA 3 0.0001
275 INFLUENZA 7 0.0001
276 TACHYCARDIA 6 0.0001
277 BLOOD ALKALINE PHOSPHATASE INCREASED 2 0.0001
278 RESPIRATORY DISTRESS 2 0.0001
279 HYPERSENSITIVITY 12 0.0001
280 BLOOD POTASSIUM DECREASED 2 0.0001
281 LIVER INJURY 1 0.0001
282 MUSCULOSKELETAL CHEST PAIN 1 0.0001
283 HEAD INJURY 2 0.0001
284 HYPOAESTHESIA ORAL 1 0.0001
285 HEART RATE DECREASED 2 0.0001
286 VOMITING 29 0.0001
287 CYTOMEGALOVIRUS INFECTION 1 0.0001
288 WEIGHT INCREASED 13 0.0001
289 ABDOMINAL PAIN UPPER 12 0.0001
290 PRURITUS GENERALISED 2 0.0001
291 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 4 0.0001
292 IRRITABLE BOWEL SYNDROME 1 0.0001
293 COAGULOPATHY 1 0.0001
294 UPPER GASTROINTESTINAL HAEMORRHAGE 1 0.0001
295 BLOOD LACTATE DEHYDROGENASE INCREASED 1 0.0001
296 SEPSIS 6 0.0001
297 SINUS DISORDER 1 0.0001
298 RHINORRHOEA 3 0.0001
299 PANIC ATTACK 2 0.0001
300 POOR QUALITY SLEEP 1 0.0001
301 SLEEP APNOEA SYNDROME 1 0.0001
302 DIARRHOEA 29 0.0001
303 INCORRECT PRODUCT STORAGE 1 0.0001
304 DEVICE BREAKAGE 1 0.0001
305 GALLBLADDER DISORDER 1 0.0001
306 HAEMORRHOIDS 1 0.0001
307 BLOOD UREA INCREASED 1 0.0001
308 LETHARGY 3 0.0001
309 INFLAMMATION 2 0.0001
310 THROAT IRRITATION 2 0.0001
311 POST PROCEDURAL COMPLICATION 1 0.0001
312 HAEMATOCRIT DECREASED 1 0.0001
313 PHARYNGEAL OEDEMA 1 0.0001
314 THERAPEUTIC RESPONSE UNEXPECTED 2 0.0001
315 DRUG ADMINISTRATION ERROR 2 0.0001
316 UNDERDOSE 3 0.0001
317 EYE PRURITUS 1 0.0001
318 PLATELET COUNT DECREASED 4 0.0001
319 LEUKOPENIA 2 0.0001
320 RASH PAPULAR 1 0.0001
321 COUGH 10 0.0001
322 RASH PRURITIC 2 0.0001
323 NASAL CONGESTION 2 0.0001
324 PREGNANCY 1 0.0001
325 PROCEDURAL PAIN 1 0.0001
326 ABDOMINAL PAIN 9 0.0001
327 ARRHYTHMIA 2 0.0001
328 CONDITION AGGRAVATED 9 0.0001
329 THERAPY NON-RESPONDER 1 0.0001
330 FLATULENCE 2 0.0001
331 DRUG EFFECT INCOMPLETE 2 0.0001
332 HYPOTHYROIDISM 1 0.0001
333 THERAPEUTIC RESPONSE DECREASED 2 0.0001
334 METABOLIC ACIDOSIS 1 0.0001
335 WEIGHT DECREASED 9 0.0001
336 RESPIRATORY DISORDER 1 0.0001
337 HAEMOPTYSIS 1 0.0001
338 RASH MACULAR 1 0.0000
339 PRODUCT STORAGE ERROR 1 0.0000
340 OFF LABEL USE 17 0.0000
341 HEART RATE INCREASED 3 0.0000
342 CHEST DISCOMFORT 3 0.0000
343 INJECTION SITE MASS 1 0.0000
344 SINUSITIS 3 0.0000
345 ANGINA PECTORIS 1 0.0000
346 HYPOXIA 1 0.0000
347 HEADACHE 19 0.0000
348 NEUTROPHIL COUNT DECREASED 1 0.0000
349 MALAISE 14 0.0000
350 ADVERSE DRUG REACTION 2 0.0000
351 HEPATIC FUNCTION ABNORMAL 1 0.0000
352 GASTROINTESTINAL DISORDER 2 0.0000
353 SWOLLEN TONGUE 1 0.0000
354 HAEMOGLOBIN DECREASED 3 0.0000
355 FEMUR FRACTURE 1 0.0000
356 PRODUCT DOSE OMISSION 3 0.0000
357 CHOLELITHIASIS 1 0.0000
358 EYE SWELLING 1 0.0000
359 STAPHYLOCOCCAL INFECTION 1 0.0000
360 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 3 0.0000
361 ABDOMINAL DISCOMFORT 4 0.0000
362 LOWER RESPIRATORY TRACT INFECTION 1 0.0000
363 RESTLESSNESS 1 0.0000
364 FLUSHING 3 0.0000
365 PNEUMONIA 8 0.0000
366 INTERNATIONAL NORMALISED RATIO INCREASED 1 0.0000
367 HOSPITALISATION 3 0.0000
368 GASTROOESOPHAGEAL REFLUX DISEASE 2 0.0000
369 OCULAR HYPERAEMIA 1 0.0000
370 PALPITATIONS 3 0.0000
371 RASH ERYTHEMATOUS 1 0.0000
372 WHITE BLOOD CELL COUNT INCREASED 1 0.0000
373 PRODUCT QUALITY ISSUE 4 0.0000
374 CRYING 1 0.0000
375 MIGRAINE 2 0.0000
376 OROPHARYNGEAL PAIN 2 0.0000
377 INCORRECT DRUG ADMINISTRATION DURATION 1 0.0000
378 OXYGEN SATURATION DECREASED 1 0.0000
379 DISCOMFORT 1 0.0000
380 EYE IRRITATION 1 0.0000
381 HYPOKALAEMIA 1 0.0000
382 DISORIENTATION 1 0.0000
383 LUNG DISORDER 1 0.0000
384 UPPER RESPIRATORY TRACT INFECTION 1 0.0000
385 HAEMATOCHEZIA 1 0.0000
386 SKIN DISCOLOURATION 1 0.0000
387 EYE PAIN 1 0.0000
388 DEHYDRATION 3 0.0000
389 TREATMENT NONCOMPLIANCE 1 0.0000
390 GENERAL PHYSICAL HEALTH DETERIORATION 2 0.0000
391 CARDIO-RESPIRATORY ARREST 1 0.0000
392 DISEASE PROGRESSION 2 0.0000
393 WHITE BLOOD CELL COUNT DECREASED 2 0.0000
394 ABNORMAL BEHAVIOUR 1 0.0000
395 DEPRESSED MOOD 1 0.0000
396 BLISTER 1 0.0000
397 FLUID RETENTION 1 0.0000
398 URINARY TRACT INFECTION 3 0.0000
399 EXPOSURE DURING PREGNANCY 1 0.0000
400 DECREASED APPETITE 4 0.0000
401 THROMBOCYTOPENIA 2 0.0000
402 OEDEMA 1 0.0000
403 PANCYTOPENIA 1 0.0000
404 BLOOD GLUCOSE DECREASED 1 0.0000
405 NECK PAIN 1 0.0000
406 NASOPHARYNGITIS 3 0.0000
407 DRUG INEFFECTIVE 21 0.0000
408 MEDICATION ERROR 1 0.0000
409 NAUSEA 13 0.0000
410 DEVICE ISSUE 1 0.0000
411 NERVOUSNESS 1 0.0000
412 MATERNAL EXPOSURE DURING PREGNANCY 1 0.0000
413 PRURITUS 5 0.0000
414 PERIPHERAL SWELLING 2 0.0000
415 INFECTION 2 0.0000
416 CONSTIPATION 3 0.0000
417 FATIGUE 11 0.0000
418 STRESS 1 0.0000
419 MOBILITY DECREASED 1 0.0000
420 HYPOTENSION 3 0.0000
421 SWELLING FACE 1 0.0000
422 DRUG HYPERSENSITIVITY 3 0.0000
423 HYPERHIDROSIS 2 0.0000
424 BLOOD CREATININE INCREASED 1 0.0000
425 ERYTHEMA 3 0.0000
426 FOETAL EXPOSURE DURING PREGNANCY 1 0.0000
427 INJECTION SITE REACTION 1 0.0000
428 ANXIETY 4 0.0000
429 ARTHRITIS 1 0.0000
430 RENAL FAILURE 2 0.0000
431 ASTHENIA 5 0.0000
432 TOXICITY TO VARIOUS AGENTS 2 0.0000
433 DRUG ABUSE 1 0.0000
434 HYPOAESTHESIA 2 0.0000
435 DRUG INTOLERANCE 1 0.0000
436 THROMBOSIS 1 0.0000
437 ACNE 1 0.0000
438 DRY MOUTH 1 0.0000
439 MUSCULOSKELETAL STIFFNESS 1 0.0000
440 BRONCHITIS 1 0.0000
441 AGITATION 1 0.0000
442 DRUG EFFECT DECREASED 1 0.0000
443 ASTHMA 1 0.0000
444 SEIZURE 1 0.0000
445 CONTUSION 1 0.0000
446 INFLUENZA LIKE ILLNESS 1 0.0000
447 MUSCLE SPASMS 2 0.0000
448 ADVERSE EVENT 1 0.0000
449 CARDIAC DISORDER 1 0.0000
450 ANAEMIA 2 0.0000
451 HAEMORRHAGE 1 0.0000
452 CARDIAC FAILURE CONGESTIVE 1 0.0000
453 SYNCOPE 1 0.0000
454 NEUTROPENIA 1 0.0000
455 FALL 3 0.0000
456 DEATH 7 0.0000
457 BACK PAIN 2 0.0000
458 DIZZINESS 4 0.0000
459 FEELING ABNORMAL 2 0.0000
460 DRUG DOSE OMISSION 2 0.0000
461 ACUTE KIDNEY INJURY 1 0.0000
462 RASH 3 0.0000
463 INJECTION SITE ERYTHEMA 1 0.0000
464 LOSS OF CONSCIOUSNESS 1 0.0000
465 DYSPNOEA 4 0.0000
466 OEDEMA PERIPHERAL 1 0.0000
467 PRODUCT USE IN UNAPPROVED INDICATION 1 0.0000
468 BLOOD PRESSURE INCREASED 1 0.0000
469 PRODUCT USE ISSUE 1 0.0000
470 PARAESTHESIA 1 0.0000
471 CONFUSIONAL STATE 1 0.0000
472 OVERDOSE 1 0.0000
473 TREMOR 1 0.0000
474 PAIN 3 0.0000
475 GAIT DISTURBANCE 1 0.0000
476 ALOPECIA 1 0.0000
477 CHEST PAIN 1 0.0000
478 SOMNOLENCE 1 0.0000
479 HYPERTENSION 1 0.0000
480 BLOOD GLUCOSE INCREASED 1 0.0000
481 DEPRESSION 1 0.0000
482 INJECTION SITE PAIN 1 0.0000
483 PAIN IN EXTREMITY 1 0.0000