SIROLIMUS

SIROLIMUS was reported 13848 times

SIROLIMUS is most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 COW POX 9 0.9000
1 TRANSPLANT DYSFUNCTION 477 0.3807
2 AVIAN INFLUENZA 14 0.3256
3 BRONCHIOLITIS OBLITERANS SYNDROME 10 0.2857
4 FOCAL GLOMERULOSCLEROSIS 29 0.2736
5 NEUROFIBROSARCOMA 13 0.2653
6 SKIN SQUAMOUS CELL CARCINOMA METASTATIC 13 0.2600
7 SMOOTH MUSCLE CELL NEOPLASM 33 0.1875
8 RENAL GRAFT INFECTION 21 0.1750
9 PROPIONIBACTERIUM INFECTION 17 0.1683
10 GRAFT DYSFUNCTION 41 0.1434
11 TRANSPLANT REJECTION 788 0.1425
12 ADJUSTED CALCIUM DECREASED 9 0.1385
13 ALOPECIA SCARRING 14 0.1321
14 LYMPHOCELE 77 0.1314
15 CHRONIC ALLOGRAFT NEPHROPATHY 73 0.1297
16 INTESTINE TRANSPLANT REJECTION 9 0.1286
17 MELAS SYNDROME 14 0.1261
18 PANCREAS TRANSPLANT REJECTION 19 0.1195
19 KIDNEY TRANSPLANT REJECTION 452 0.1192
20 PERINEPHRIC COLLECTION 12 0.1154
21 COMPLICATIONS OF TRANSPLANTED KIDNEY 181 0.1073
22 PNEUMONIA ADENOVIRAL 10 0.1042
23 HEPATIC NEOPLASM MALIGNANT RECURRENT 10 0.0943
24 CYTOMEGALOVIRUS SYNDROME 11 0.0932
25 COMPLICATIONS OF TRANSPLANT SURGERY 41 0.0923
26 LIVER TRANSPLANT REJECTION 121 0.0853
27 HEART TRANSPLANT REJECTION 68 0.0838
28 IMMUNOSUPPRESSANT DRUG LEVEL INCREASED 152 0.0762
29 HUMAN HERPESVIRUS 8 INFECTION 24 0.0757
30 SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE 174 0.0750
31 CHRONIC GRAFT VERSUS HOST DISEASE IN SKIN 35 0.0737
32 HERPES ZOSTER MENINGOENCEPHALITIS 15 0.0732
33 IMMUNOSUPPRESSANT DRUG LEVEL DECREASED 63 0.0694
34 CYSTITIS VIRAL 12 0.0678
35 BIOPSY KIDNEY ABNORMAL 12 0.0678
36 HUMAN POLYOMAVIRUS INFECTION 22 0.0669
37 ADENOVIRUS INFECTION 114 0.0642
38 KIDNEY FIBROSIS 76 0.0617
39 COMPLICATIONS OF TRANSPLANTED HEART 10 0.0610
40 BK VIRUS INFECTION 116 0.0608
41 GRAFT LOSS 36 0.0603
42 CRYPTOSPORIDIOSIS INFECTION 17 0.0601
43 GRAFT VERSUS HOST DISEASE IN LIVER 26 0.0594
44 LUNG TRANSPLANT REJECTION 27 0.0588
45 GRAFT VERSUS HOST DISEASE IN GASTROINTESTINAL TRACT 75 0.0587
46 CYTOMEGALOVIRUS INFECTION REACTIVATION 64 0.0581
47 GRAFT THROMBOSIS 12 0.0553
48 MORPHOEA 15 0.0549
49 POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER 154 0.0549
50 OVARIAN CYST 435 0.0543
51 ALVEOLAR PROTEINOSIS 17 0.0538
52 GLOBULINS DECREASED 11 0.0529
53 CHRONIC GRAFT VERSUS HOST DISEASE IN LIVER 10 0.0518
54 POLYOMAVIRUS VIRAEMIA 16 0.0510
55 PLASMABLASTIC LYMPHOMA 10 0.0495
56 GRAFT VERSUS HOST DISEASE IN SKIN 70 0.0495
57 POLYOMAVIRUS-ASSOCIATED NEPHROPATHY 63 0.0482
58 URINARY TRACT INFECTION PSEUDOMONAL 21 0.0478
59 ALTERNARIA INFECTION 9 0.0474
60 PTERYGIUM 11 0.0464
61 TRANSPLANT FAILURE 79 0.0449
62 THROMBOTIC MICROANGIOPATHY 264 0.0448
63 CHRONIC GRAFT VERSUS HOST DISEASE 100 0.0416
64 URETERIC STENOSIS 24 0.0407
65 TRICHODYSPLASIA SPINULOSA 10 0.0402
66 RENAL TUBULAR ATROPHY 25 0.0401
67 PLEOCYTOSIS 16 0.0391
68 RED BLOOD CELL SCHISTOCYTES PRESENT 11 0.0385
69 EPSTEIN-BARR VIRUS INFECTION 161 0.0380
70 CITROBACTER INFECTION 11 0.0379
71 GRAFT COMPLICATION 17 0.0378
72 SCEDOSPORIUM INFECTION 15 0.0377
73 PNEUMONIA HAEMOPHILUS 10 0.0376
74 OBLITERATIVE BRONCHIOLITIS 38 0.0369
75 HUMAN HERPESVIRUS 6 INFECTION 53 0.0368
76 GRAFT VERSUS HOST DISEASE 198 0.0362
77 EPSTEIN-BARR VIRUS ASSOCIATED LYMPHOPROLIFERATIVE DISORDER 40 0.0351
78 GLOMERULONEPHRITIS PROLIFERATIVE 10 0.0347
79 ACUTE GRAFT VERSUS HOST DISEASE 117 0.0345
80 INFECTION IN AN IMMUNOCOMPROMISED HOST 16 0.0340
81 EPSTEIN-BARR VIRAEMIA 19 0.0332
82 METASTATIC SQUAMOUS CELL CARCINOMA 12 0.0330
83 GLOMERULOSCLEROSIS 16 0.0327
84 DIAPHRAGMATIC HERNIA 15 0.0325
85 ACUTE GRAFT VERSUS HOST DISEASE IN SKIN 55 0.0325
86 RETINAL SCAR 12 0.0317
87 TRANSITIONAL CELL CARCINOMA 25 0.0305
88 VIRAEMIA 24 0.0304
89 MICROANGIOPATHIC HAEMOLYTIC ANAEMIA 16 0.0296
90 ACUTE GRAFT VERSUS HOST DISEASE IN INTESTINE 27 0.0294
91 COMPLICATIONS OF TRANSPLANTED LIVER 9 0.0293
92 CYTOMEGALOVIRUS VIRAEMIA 67 0.0286
93 EPSTEIN-BARR VIRUS INFECTION REACTIVATION 9 0.0279
94 JC VIRUS INFECTION 27 0.0277
95 PNEUMONIA CYTOMEGALOVIRAL 35 0.0275
96 NOCARDIOSIS 43 0.0268
97 NEUROENDOCRINE CARCINOMA OF THE SKIN 16 0.0266
98 TOXOPLASMOSIS 21 0.0265
99 HAEMOLYTIC URAEMIC SYNDROME 51 0.0259
100 KAPOSI'S SARCOMA 13 0.0258
101 PULMONARY CAVITATION 13 0.0258
102 ACUTE GRAFT VERSUS HOST DISEASE IN LIVER 12 0.0252
103 MICROANGIOPATHY 17 0.0251
104 CENTRAL NERVOUS SYSTEM LYMPHOMA 20 0.0250
105 VENOOCCLUSIVE LIVER DISEASE 80 0.0247
106 NEPHROGENIC DIABETES INSIPIDUS 20 0.0246
107 HEPATITIS E 24 0.0243
108 ENTEROVIRUS INFECTION 10 0.0239
109 ACINETOBACTER INFECTION 18 0.0237
110 MENINGITIS VIRAL 25 0.0235
111 CYTOMEGALOVIRUS INFECTION 263 0.0230
112 DRUG LEVEL FLUCTUATING 15 0.0228
113 ASPERGILLOSIS 29 0.0222
114 NECROTISING RETINITIS 9 0.0219
115 FUSARIUM INFECTION 9 0.0218
116 POUCHITIS 11 0.0214
117 GASTROENTERITIS NOROVIRUS 23 0.0214
118 VENOOCCLUSIVE DISEASE 37 0.0213
119 ZYGOMYCOSIS 10 0.0213
120 PNEUMOCYSTIS JIROVECII INFECTION 12 0.0212
121 CEREBRAL TOXOPLASMOSIS 12 0.0212
122 CYTOMEGALOVIRUS COLITIS 27 0.0211
123 RENAL TRANSPLANT FAILURE 13 0.0210
124 URINARY TRACT INFECTION ENTEROCOCCAL 16 0.0209
125 ILEAL ULCER 12 0.0209
126 PNEUMONIA STREPTOCOCCAL 16 0.0208
127 VARICELLA ZOSTER VIRUS INFECTION 26 0.0208
128 NEPHROPATHY TOXIC 141 0.0202
129 ABDOMINAL WALL ABSCESS 9 0.0200
130 NORMOCYTIC ANAEMIA 14 0.0200
131 BRAIN ABSCESS 32 0.0197
132 RHINOVIRUS INFECTION 32 0.0194
133 CYTOMEGALOVIRUS CHORIORETINITIS 24 0.0189
134 OSMOTIC DEMYELINATION SYNDROME 9 0.0184
135 SQUAMOUS CELL CARCINOMA OF SKIN 70 0.0182
136 DYSPLASIA 15 0.0182
137 KLEBSIELLA SEPSIS 14 0.0181
138 RENAL TUBULAR NECROSIS 126 0.0178
139 PNEUMONIA PSEUDOMONAL 13 0.0175
140 ENTEROCOCCAL SEPSIS 11 0.0175
141 HEART TRANSPLANT 10 0.0173
142 HAEMOPHILUS INFECTION 11 0.0172
143 BRONCHOPULMONARY ASPERGILLOSIS 83 0.0170
144 SEROMA 16 0.0170
145 HYPERTRIGLYCERIDAEMIA 66 0.0165
146 FOCAL SEGMENTAL GLOMERULOSCLEROSIS 17 0.0163
147 KLEBSIELLA INFECTION 52 0.0162
148 ESCHERICHIA TEST POSITIVE 14 0.0162
149 SPUTUM CULTURE POSITIVE 11 0.0162
150 PSEUDOMONAS INFECTION 88 0.0162
151 DRUG LEVEL BELOW THERAPEUTIC 49 0.0158
152 ALPHA HAEMOLYTIC STREPTOCOCCAL INFECTION 9 0.0157
153 GRAVITATIONAL OEDEMA 9 0.0155
154 PYELONEPHRITIS ACUTE 21 0.0152
155 PULMONARY MYCOSIS 12 0.0151
156 SQUAMOUS CELL CARCINOMA 102 0.0151
157 ENTEROCOCCAL INFECTION 47 0.0146
158 WHITE MATTER LESION 11 0.0146
159 OPHTHALMIC HERPES ZOSTER 15 0.0145
160 BLOOD CREATINE INCREASED 44 0.0143
161 PULMONARY TOXICITY 54 0.0141
162 RENAL TRANSPLANT 35 0.0141
163 BLOOD ALBUMIN INCREASED 9 0.0140
164 PROTEINURIA 166 0.0138
165 LUPUS NEPHRITIS 12 0.0137
166 BLADDER TRANSITIONAL CELL CARCINOMA 16 0.0135
167 MUCORMYCOSIS 21 0.0134
168 LYMPHOPROLIFERATIVE DISORDER 26 0.0133
169 ENTEROBACTER INFECTION 15 0.0131
170 ACTINIC KERATOSIS 25 0.0130
171 BACTERIAL SEPSIS 30 0.0129
172 CLOSTRIDIUM TEST POSITIVE 15 0.0129
173 HAEMODIALYSIS 101 0.0127
174 RENAL ARTERY STENOSIS 14 0.0127
175 NEPHROSCLEROSIS 12 0.0126
176 ESCHERICHIA BACTERAEMIA 17 0.0125
177 ELECTROMECHANICAL DISSOCIATION 10 0.0125
178 POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME 75 0.0124
179 PROCTITIS 20 0.0122
180 PNEUMATOSIS INTESTINALIS 21 0.0121
181 STEM CELL TRANSPLANT 21 0.0119
182 PNEUMONIA FUNGAL 22 0.0118
183 IMMUNE THROMBOCYTOPENIA 14 0.0118
184 VARICELLA 21 0.0117
185 ALVEOLITIS ALLERGIC 12 0.0116
186 DIFFUSE ALVEOLAR DAMAGE 10 0.0115
187 MYCOBACTERIUM AVIUM COMPLEX INFECTION 18 0.0115
188 BILE DUCT STENOSIS 10 0.0114
189 DRUG LEVEL INCREASED 130 0.0114
190 ESCHERICHIA INFECTION 60 0.0113
191 RENAL ATROPHY 11 0.0112
192 WOUND DEHISCENCE 29 0.0111
193 PNEUMOCYSTIS JIROVECII PNEUMONIA 64 0.0110
194 HEPATIC FIBROSIS 26 0.0109
195 CULTURE URINE POSITIVE 13 0.0108
196 MYCOSIS FUNGOIDES 9 0.0108
197 ASPERGILLUS INFECTION 38 0.0107
198 HYDRONEPHROSIS 57 0.0107
199 CLOSTRIDIUM COLITIS 11 0.0107
200 LUNG CONSOLIDATION 22 0.0107
201 DRUG LEVEL DECREASED 62 0.0106
202 ALVEOLITIS 13 0.0106
203 LIVEDO RETICULARIS 16 0.0105
204 INCISIONAL HERNIA 11 0.0105
205 DRUG LEVEL ABOVE THERAPEUTIC 26 0.0103
206 PNEUMONIA KLEBSIELLA 12 0.0102
207 OPPORTUNISTIC INFECTION 14 0.0101
208 PAPILLOMA VIRAL INFECTION 11 0.0101
209 NEPHROTIC SYNDROME 48 0.0100
210 ESCHERICHIA URINARY TRACT INFECTION 31 0.0100
211 DIFFUSE LARGE B-CELL LYMPHOMA 39 0.0098
212 LIP HAEMORRHAGE 9 0.0098
213 ADENOCARCINOMA 16 0.0098
214 SALMONELLOSIS 10 0.0098
215 BLOOD CREATININE INCREASED 468 0.0097
216 URETERIC OBSTRUCTION 10 0.0096
217 APLASIA PURE RED CELL 24 0.0096
218 RENAL TUBULAR DISORDER 22 0.0095
219 PNEUMOMEDIASTINUM 10 0.0094
220 MICROCYTIC ANAEMIA 15 0.0094
221 NEPHRECTOMY 9 0.0093
222 BONE MARROW DEPRESSION 9 0.0092
223 GLOMERULONEPHRITIS 15 0.0092
224 ENDOCARDITIS 33 0.0092
225 BLOOD CHLORIDE INCREASED 11 0.0090
226 LUNG INFILTRATION 68 0.0090
227 IMMUNOSUPPRESSION 45 0.0089
228 THROMBOTIC THROMBOCYTOPENIC PURPURA 26 0.0089
229 CATHETER RELATED INFECTION 9 0.0089
230 MOUTH ULCERATION 124 0.0088
231 SCLERODERMA 24 0.0087
232 PULMONARY ALVEOLAR HAEMORRHAGE 31 0.0087
233 CYSTITIS HAEMORRHAGIC 24 0.0086
234 LYMPHOEDEMA 38 0.0085
235 DILATATION ATRIAL 9 0.0084
236 NEPHROGENIC SYSTEMIC FIBROSIS 25 0.0084
237 LEUKAEMIA RECURRENT 11 0.0084
238 PNEUMONITIS 139 0.0083
239 CRANIOCEREBRAL INJURY 16 0.0082
240 LIVER FUNCTION TEST ABNORMAL 204 0.0082
241 RENAL MASS 12 0.0082
242 HYPOGAMMAGLOBULINAEMIA 26 0.0081
243 LOBAR PNEUMONIA 15 0.0081
244 ENTERITIS 32 0.0081
245 LIVER TRANSPLANT 22 0.0081
246 HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS 19 0.0080
247 HYPERLIPIDAEMIA 76 0.0079
248 NEPHRITIS INTERSTITIAL 10 0.0079
249 ACNE 470 0.0078
250 ORGANISING PNEUMONIA 23 0.0078
251 PRODUCT USE IN UNAPPROVED INDICATION 918 0.0077
252 ESCHERICHIA SEPSIS 16 0.0076
253 LUNG ABSCESS 11 0.0075
254 GASTROINTESTINAL ULCER 13 0.0075
255 PULMONARY HAEMORRHAGE 46 0.0075
256 AUTOIMMUNE HAEMOLYTIC ANAEMIA 15 0.0075
257 HERPES SIMPLEX 34 0.0074
258 LARGE INTESTINAL ULCER 14 0.0073
259 RENAL FAILURE CHRONIC 56 0.0073
260 MULTIPLE ORGAN DYSFUNCTION SYNDROME 109 0.0073
261 BLOOD CREATININE ABNORMAL 16 0.0071
262 VENTRICULAR HYPERTROPHY 16 0.0071
263 SKIN EROSION 14 0.0071
264 RENAL HAEMORRHAGE 11 0.0070
265 BLOOD BICARBONATE DECREASED 11 0.0070
266 PORTAL VEIN THROMBOSIS 16 0.0069
267 PYELONEPHRITIS 41 0.0069
268 PERICARDIAL EFFUSION 108 0.0069
269 CONCOMITANT DISEASE PROGRESSION 12 0.0069
270 WOUND INFECTION STAPHYLOCOCCAL 10 0.0068
271 ERYTHEMA NODOSUM 15 0.0068
272 FAECES SOFT 23 0.0068
273 LEUKOENCEPHALOPATHY 19 0.0067
274 MULTI-ORGAN FAILURE 116 0.0067
275 CHOLANGITIS 26 0.0067
276 METASTATIC MALIGNANT MELANOMA 11 0.0067
277 HYPOALBUMINAEMIA 34 0.0067
278 MYOPATHY 42 0.0066
279 FIBROSIS 15 0.0066
280 STAPHYLOCOCCAL BACTERAEMIA 18 0.0065
281 APHTHOUS STOMATITIS 15 0.0065
282 BLOOD UREA INCREASED 89 0.0065
283 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 48 0.0065
284 DIASTOLIC DYSFUNCTION 14 0.0064
285 AZOTAEMIA 18 0.0063
286 RENAL IMPAIRMENT 348 0.0063
287 HISTIOCYTOSIS HAEMATOPHAGIC 19 0.0063
288 GASTROENTERITIS 66 0.0063
289 PRODUCT ADMINISTERED TO PATIENT OF INAPPROPRIATE AGE 16 0.0062
290 HEPATITIS B 29 0.0062
291 METASTATIC NEOPLASM 18 0.0062
292 CACHEXIA 23 0.0061
293 DUODENITIS 14 0.0061
294 HEPATIC NECROSIS 19 0.0061
295 BASAL CELL CARCINOMA 66 0.0061
296 ANURIA 41 0.0059
297 HYPERBILIRUBINAEMIA 42 0.0059
298 CLOSTRIDIUM DIFFICILE INFECTION 81 0.0059
299 BRONCHIECTASIS 23 0.0058
300 VENTRICULAR HYPOKINESIA 14 0.0058
301 SKIN CANCER 77 0.0058
302 ORAL INTAKE REDUCED 14 0.0058
303 DYSLIPIDAEMIA 20 0.0058
304 RETROPERITONEAL HAEMATOMA 10 0.0058
305 LYMPHOPENIA 53 0.0058
306 RESPIRATORY SYNCYTIAL VIRUS INFECTION 20 0.0057
307 NEOPLASM RECURRENCE 13 0.0056
308 DRUG TOXICITY 76 0.0056
309 OESOPHAGEAL CANDIDIASIS 15 0.0056
310 DIALYSIS 62 0.0056
311 ATELECTASIS 42 0.0056
312 HAEMATOCRIT DECREASED 87 0.0055
313 CLOSTRIDIUM DIFFICILE COLITIS 41 0.0055
314 COMPUTERISED TOMOGRAM ABNORMAL 10 0.0055
315 ENCEPHALITIS 25 0.0055
316 PNEUMONIA VIRAL 11 0.0054
317 MALNUTRITION 41 0.0054
318 NECROTISING FASCIITIS 13 0.0054
319 DIARRHOEA HAEMORRHAGIC 36 0.0054
320 INTERSTITIAL LUNG DISEASE 173 0.0054
321 DIABETIC FOOT 13 0.0054
322 HERPES VIRUS INFECTION 22 0.0053
323 BACTERAEMIA 40 0.0053
324 B-CELL LYMPHOMA 14 0.0053
325 APLASTIC ANAEMIA 19 0.0053
326 PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY 31 0.0052
327 SKIN HYPERTROPHY 10 0.0051
328 SEPTIC SHOCK 148 0.0051
329 ORAL DISORDER 27 0.0051
330 OLIGURIA 24 0.0051
331 LIVER ABSCESS 11 0.0051
332 PATHOGEN RESISTANCE 28 0.0051
333 HIV INFECTION 11 0.0050
334 GLOMERULAR FILTRATION RATE DECREASED 35 0.0050
335 LUNG NEOPLASM 18 0.0050
336 APHTHOUS ULCER 19 0.0050
337 WOUND COMPLICATION 12 0.0050
338 RENAL FAILURE ACUTE 211 0.0050
339 BRONCHOPNEUMONIA 17 0.0050
340 HEPATIC NEOPLASM 12 0.0049
341 PROTEIN URINE PRESENT 17 0.0049
342 GRANULOMA 12 0.0049
343 NECROSIS 21 0.0049
344 PAPILLOEDEMA 16 0.0049
345 BLOOD LACTATE DEHYDROGENASE INCREASED 61 0.0048
346 NEPHROGENIC ANAEMIA 19 0.0048
347 HAEMORRHAGIC DIATHESIS 13 0.0048
348 ACUTE RESPIRATORY DISTRESS SYNDROME 60 0.0048
349 BLOOD PHOSPHORUS DECREASED 11 0.0047
350 CANDIDIASIS 19 0.0047
351 BILE DUCT OBSTRUCTION 9 0.0047
352 BLOOD TRIGLYCERIDES INCREASED 65 0.0047
353 PORTAL HYPERTENSION 10 0.0046
354 HEPATIC ENCEPHALOPATHY 32 0.0046
355 HYPOVOLAEMIA 20 0.0046
356 HEPATOSPLENOMEGALY 9 0.0045
357 PROSTATE CANCER METASTATIC 10 0.0045
358 SKIN NECROSIS 18 0.0045
359 DISEASE RECURRENCE 74 0.0045
360 IMPAIRED HEALING 97 0.0044
361 SYSTEMIC INFLAMMATORY RESPONSE SYNDROME 13 0.0044
362 HYPOPHOSPHATAEMIA 21 0.0044
363 POTENTIATING DRUG INTERACTION 10 0.0044
364 HYPERPARATHYROIDISM SECONDARY 9 0.0043
365 PROTEIN TOTAL DECREASED 12 0.0043
366 COVID-19 PNEUMONIA 16 0.0043
367 GINGIVITIS 17 0.0043
368 RENAL CELL CARCINOMA 16 0.0043
369 BACTERIAL INFECTION 51 0.0043
370 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 101 0.0042
371 PRODUCT USE ISSUE 498 0.0042
372 BLOOD ALBUMIN DECREASED 25 0.0042
373 CREPITATIONS 10 0.0042
374 HAEMOLYSIS 24 0.0042
375 DRUG RESISTANCE 68 0.0042
376 FLUID OVERLOAD 61 0.0041
377 PHARYNGITIS 38 0.0041
378 CUSHINGOID 9 0.0041
379 FAILURE TO THRIVE 17 0.0041
380 CANDIDA INFECTION 42 0.0041
381 MALIGNANT MELANOMA 40 0.0041
382 PNEUMONIA BACTERIAL 20 0.0041
383 RESPIRATORY FAILURE 222 0.0041
384 ABDOMINAL HERNIA 14 0.0041
385 PLEURAL EFFUSION 182 0.0040
386 BLOOD DISORDER 23 0.0040
387 NEPHROPATHY 29 0.0040
388 DRUG EFFECTIVE FOR UNAPPROVED INDICATION 34 0.0040
389 METASTASES TO LYMPH NODES 17 0.0040
390 PERICARDITIS 29 0.0040
391 METASTASES TO LUNG 30 0.0040
392 NAIL DISCOLOURATION 11 0.0040
393 LEFT VENTRICULAR FAILURE 10 0.0040
394 HEPATOCELLULAR CARCINOMA 22 0.0040
395 LEUKOPENIA 138 0.0039
396 NORMOCHROMIC NORMOCYTIC ANAEMIA 9 0.0039
397 ACUTE PULMONARY OEDEMA 17 0.0039
398 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME 14 0.0039
399 HEPATIC ENZYME ABNORMAL 13 0.0039
400 VIRAL INFECTION 85 0.0038
401 METASTASIS 18 0.0038
402 GASTROINTESTINAL TOXICITY 10 0.0038
403 CHOLESTASIS 50 0.0038
404 DRUG INTERACTION 442 0.0038
405 HYPOVOLAEMIC SHOCK 13 0.0038
406 GUILLAIN-BARRE SYNDROME 12 0.0038
407 ANGIONEUROTIC OEDEMA 10 0.0037
408 OESOPHAGITIS 30 0.0037
409 HYPERCHOLESTEROLAEMIA 22 0.0037
410 TRANSAMINASES INCREASED 60 0.0037
411 MENINGITIS ASEPTIC 11 0.0037
412 HYPOXIA 87 0.0036
413 STAPHYLOCOCCAL INFECTION 92 0.0036
414 CYTOLYTIC HEPATITIS 12 0.0036
415 VENOUS THROMBOSIS 11 0.0036
416 MITRAL VALVE INCOMPETENCE 31 0.0036
417 ALOPECIA 511 0.0036
418 RESPIRATORY DISTRESS 74 0.0036
419 PRODUCT PRESCRIBING ERROR 37 0.0035
420 ASCITES 74 0.0035
421 SMALL INTESTINAL OBSTRUCTION 30 0.0035
422 PANCYTOPENIA 133 0.0035
423 RHINITIS 19 0.0034
424 MUCOSAL INFLAMMATION 62 0.0034
425 DIABETES MELLITUS 197 0.0034
426 OFF LABEL USE 1470 0.0034
427 WOUND INFECTION 21 0.0034
428 HEPATITIS C 36 0.0034
429 SKIN INFECTION 24 0.0033
430 STREPTOCOCCAL INFECTION 12 0.0033
431 THROMBOSIS IN DEVICE 10 0.0033
432 CYTOPENIA 17 0.0033
433 POST PROCEDURAL COMPLICATION 48 0.0033
434 HAEMOGLOBIN DECREASED 248 0.0033
435 OESOPHAGEAL ULCER 10 0.0033
436 BLOOD IRON DECREASED 23 0.0033
437 LEG AMPUTATION 11 0.0033
438 CREATININE RENAL CLEARANCE DECREASED 10 0.0033
439 SHOCK HAEMORRHAGIC 18 0.0033
440 FOLLICULITIS 11 0.0033
441 ABDOMINAL ABSCESS 10 0.0032
442 ODYNOPHAGIA 13 0.0032
443 SEPSIS 259 0.0032
444 NEUROTOXICITY 34 0.0032
445 COLITIS 74 0.0032
446 PULMONARY FIBROSIS 39 0.0032
447 THROMBOCYTOPENIA 243 0.0032
448 RENAL FAILURE 340 0.0032
449 CONGESTIVE CARDIOMYOPATHY 12 0.0032
450 MENTAL STATUS CHANGES 67 0.0032
451 ILEUS PARALYTIC 10 0.0031
452 HERNIA 40 0.0031
453 UROSEPSIS 20 0.0031
454 NYSTAGMUS 13 0.0031
455 ARTHRITIS BACTERIAL 9 0.0031
456 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 96 0.0031
457 ILEUS 27 0.0031
458 CARDIAC FAILURE ACUTE 13 0.0031
459 HAEMOLYTIC ANAEMIA 21 0.0031
460 BONE MARROW FAILURE 55 0.0031
461 TOE AMPUTATION 13 0.0031
462 RENAL DISORDER 100 0.0030
463 PNEUMONIA 669 0.0030
464 DUODENAL ULCER 16 0.0030
465 RESPIRATORY RATE INCREASED 19 0.0030
466 STOMATITIS 119 0.0030
467 LIVER FUNCTION TEST INCREASED 36 0.0030
468 DERMATITIS ACNEIFORM 12 0.0030
469 ELECTROLYTE IMBALANCE 23 0.0030
470 MALABSORPTION 11 0.0030
471 PNEUMOTHORAX 32 0.0030
472 ACIDOSIS 17 0.0029
473 CLOSTRIDIAL INFECTION 9 0.0029
474 LUNG INFECTION 46 0.0029
475 POSTOPERATIVE WOUND INFECTION 13 0.0029
476 PERIORBITAL OEDEMA 11 0.0029
477 URINE OUTPUT DECREASED 20 0.0029
478 HEPATIC FAILURE 67 0.0029
479 EOSINOPHIL COUNT INCREASED 16 0.0029
480 ACUTE HEPATIC FAILURE 26 0.0029
481 RALES 12 0.0029
482 BREATH SOUNDS ABNORMAL 9 0.0028
483 STAPHYLOCOCCAL SEPSIS 11 0.0028
484 IMMUNE SYSTEM DISORDER 25 0.0028
485 PARTIAL SEIZURES 10 0.0028
486 GENERALISED OEDEMA 24 0.0028
487 CELLULITIS 105 0.0028
488 ULCER 32 0.0028
489 SKIN ULCER 52 0.0028
490 PHOTOSENSITIVITY REACTION 33 0.0028
491 LUNG DISORDER 92 0.0028
492 BLOOD POTASSIUM INCREASED 33 0.0028
493 ENCEPHALOPATHY 46 0.0027
494 ANEURYSM 10 0.0027
495 CONDITION AGGRAVATED 477 0.0027
496 DYSPNOEA EXERTIONAL 66 0.0027
497 ACUTE MYELOID LEUKAEMIA 29 0.0027
498 TUBULOINTERSTITIAL NEPHRITIS 35 0.0027
499 ACUTE KIDNEY INJURY 264 0.0027
500 PYREXIA 660 0.0027
501 PULMONARY OEDEMA 88 0.0027
502 OEDEMA 101 0.0027
503 INFECTION 242 0.0026
504 EJECTION FRACTION DECREASED 28 0.0026
505 CARDIOMEGALY 27 0.0026
506 SKIN MASS 11 0.0026
507 FUNGAL INFECTION 60 0.0026
508 LYMPHOMA 28 0.0026
509 DEVICE RELATED INFECTION 31 0.0026
510 NEOPLASM 19 0.0026
511 HEPATOMEGALY 20 0.0026
512 LEUKOCYTOSIS 33 0.0026
513 LARGE INTESTINE PERFORATION 13 0.0026
514 RHEUMATOID ARTHRITIS 187 0.0025
515 COVID-19 85 0.0025
516 C-REACTIVE PROTEIN INCREASED 59 0.0025
517 HAEMOPTYSIS 52 0.0025
518 TUBERCULOSIS 22 0.0025
519 OEDEMA PERIPHERAL 241 0.0025
520 ERYSIPELAS 9 0.0025
521 BLOOD CHOLESTEROL INCREASED 80 0.0025
522 GANGRENE 12 0.0025
523 CARDIOTOXICITY 12 0.0024
524 ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED 10 0.0024
525 ORAL CANDIDIASIS 21 0.0024
526 GASTROINTESTINAL INFLAMMATION 12 0.0024
527 IMMUNODEFICIENCY 19 0.0024
528 MYELOSUPPRESSION 10 0.0024
529 FEBRILE NEUTROPENIA 100 0.0024
530 END STAGE RENAL DISEASE 36 0.0024
531 TACHYPNOEA 21 0.0024
532 RETINAL DETACHMENT 15 0.0023
533 GASTRITIS 45 0.0023
534 HEPATIC ENZYME INCREASED 101 0.0023
535 RHABDOMYOLYSIS 71 0.0023
536 MENINGITIS 11 0.0023
537 METASTASES TO LIVER 27 0.0023
538 RENAL CYST 14 0.0023
539 PLEURISY 11 0.0023
540 SKIN LESION 42 0.0023
541 LOW DENSITY LIPOPROTEIN INCREASED 12 0.0023
542 NEUROLOGICAL SYMPTOM 9 0.0023
543 ANGIOPATHY 10 0.0023
544 NEUTROPENIA 182 0.0023
545 ANAEMIA 312 0.0022
546 COLITIS ISCHAEMIC 11 0.0022
547 PERITONITIS 36 0.0022
548 HEPATITIS 41 0.0022
549 METABOLIC ACIDOSIS 47 0.0022
550 SPLENOMEGALY 19 0.0022
551 HYPOKALAEMIA 71 0.0022
552 HAEMORRHOIDS 32 0.0022
553 ECCHYMOSIS 12 0.0022
554 LEUKAEMIA 14 0.0022
555 GAMMA-GLUTAMYLTRANSFERASE INCREASED 39 0.0022
556 AUTOIMMUNE HEPATITIS 10 0.0022
557 DEFORMITY 15 0.0021
558 RED BLOOD CELL COUNT DECREASED 41 0.0021
559 HYPERGLYCAEMIA 57 0.0021
560 IRON DEFICIENCY ANAEMIA 14 0.0021
561 PHOTOPHOBIA 26 0.0021
562 IMPAIRED GASTRIC EMPTYING 11 0.0021
563 BODY HEIGHT DECREASED 19 0.0021
564 ACUTE CORONARY SYNDROME 14 0.0021
565 HAEMATURIA 56 0.0021
566 CHOLECYSTITIS ACUTE 9 0.0021
567 LYMPHADENOPATHY 52 0.0021
568 HEPATOTOXICITY 30 0.0021
569 GOUT 26 0.0021
570 DEHYDRATION 203 0.0021
571 OSTEOMYELITIS 29 0.0021
572 GENERALISED TONIC-CLONIC SEIZURE 21 0.0020
573 WEIGHT FLUCTUATION 12 0.0020
574 GASTROENTERITIS VIRAL 24 0.0020
575 CARDIAC VALVE DISEASE 9 0.0020
576 PLATELET COUNT DECREASED 145 0.0020
577 PULMONARY CONGESTION 19 0.0020
578 BLOOD BILIRUBIN INCREASED 42 0.0020
579 DISEASE PROGRESSION 141 0.0020
580 BLOOD ALKALINE PHOSPHATASE INCREASED 40 0.0020
581 APPENDICITIS 12 0.0020
582 POST PROCEDURAL HAEMORRHAGE 18 0.0020
583 AGRANULOCYTOSIS 23 0.0020
584 CARDIAC MURMUR 14 0.0020
585 RASH PUSTULAR 12 0.0020
586 PULMONARY HYPERTENSION 31 0.0019
587 HYPOMAGNESAEMIA 17 0.0019
588 HEPATIC CIRRHOSIS 24 0.0019
589 HYPERKALAEMIA 48 0.0019
590 DEEP VEIN THROMBOSIS 102 0.0019
591 SKIN PLAQUE 10 0.0019
592 ORAL HERPES 23 0.0019
593 INTENTIONAL PRODUCT USE ISSUE 88 0.0019
594 HYPERTENSION 277 0.0019
595 HAEMATOTOXICITY 10 0.0019
596 COAGULOPATHY 24 0.0019
597 FAECAL INCONTINENCE 9 0.0019
598 HEMIPLEGIA 12 0.0019
599 URINARY TRACT INFECTION 211 0.0019
600 RESPIRATORY TRACT INFECTION 31 0.0019
601 PULMONARY MASS 18 0.0018
602 ARTERIOSCLEROSIS 13 0.0018
603 NEOPLASM MALIGNANT 80 0.0018
604 METASTASES TO BONE 18 0.0018
605 HERPES ZOSTER 73 0.0018
606 OSTEONECROSIS 49 0.0018
607 HEPATOCELLULAR INJURY 22 0.0018
608 SUPRAVENTRICULAR TACHYCARDIA 13 0.0018
609 OSTEOPENIA 19 0.0018
610 GENERAL PHYSICAL HEALTH DETERIORATION 126 0.0018
611 GASTRIC ULCER 26 0.0018
612 RESPIRATORY DISORDER 38 0.0018
613 LABELLED DRUG-DRUG INTERACTION MEDICATION ERROR 12 0.0018
614 TOXICITY TO VARIOUS AGENTS 197 0.0018
615 JAUNDICE 38 0.0018
616 INTESTINAL PERFORATION 14 0.0017
617 HEMIPARESIS 23 0.0017
618 BLOOD SODIUM DECREASED 23 0.0017
619 DRUG INTOLERANCE 103 0.0017
620 OBSTRUCTIVE AIRWAYS DISORDER 13 0.0017
621 ASPARTATE AMINOTRANSFERASE INCREASED 68 0.0017
622 BLOOD CALCIUM DECREASED 14 0.0017
623 LABORATORY TEST ABNORMAL 34 0.0017
624 MYELODYSPLASTIC SYNDROME 18 0.0017
625 LARYNGITIS 12 0.0017
626 FLUID RETENTION 62 0.0017
627 ABSCESS 18 0.0017
628 BLOOD TEST ABNORMAL 14 0.0017
629 CARDIOGENIC SHOCK 15 0.0016
630 CARDIAC FAILURE 93 0.0016
631 ALANINE AMINOTRANSFERASE INCREASED 76 0.0016
632 BRAIN OEDEMA 15 0.0016
633 DIABETES MELLITUS INADEQUATE CONTROL 21 0.0016
634 POLYNEUROPATHY 12 0.0016
635 CHOLECYSTITIS 14 0.0016
636 STENT PLACEMENT 10 0.0016
637 UPPER RESPIRATORY TRACT INFECTION 51 0.0016
638 PANCREATITIS 63 0.0016
639 THERAPY NON-RESPONDER 35 0.0016
640 JOINT RANGE OF MOTION DECREASED 12 0.0016
641 HAEMATOMA 32 0.0016
642 BODY TEMPERATURE INCREASED 24 0.0016
643 CORONARY ARTERY DISEASE 42 0.0016
644 TENDERNESS 12 0.0016
645 DIARRHOEA 664 0.0016
646 ANGINA UNSTABLE 9 0.0016
647 LIVER DISORDER 47 0.0016
648 CHRONIC KIDNEY DISEASE 97 0.0015
649 MYOSITIS 9 0.0015
650 BLOOD PRESSURE SYSTOLIC INCREASED 19 0.0015
651 DRUG ADMINISTERED TO PATIENT OF INAPPROPRIATE AGE 11 0.0015
652 GRAND MAL CONVULSION 14 0.0015
653 ANGIOEDEMA 47 0.0015
654 WHITE BLOOD CELL COUNT DECREASED 109 0.0015
655 INFLAMMATION 46 0.0015
656 MELAENA 25 0.0015
657 SKIN DISORDER 31 0.0015
658 LYMPHOCYTE COUNT DECREASED 18 0.0015
659 ACUTE RESPIRATORY FAILURE 18 0.0015
660 HAEMORRHAGE INTRACRANIAL 18 0.0015
661 GASTROINTESTINAL DISORDER 73 0.0015
662 CARDIAC ARREST 92 0.0015
663 PERIPHERAL SWELLING 138 0.0014
664 PETECHIAE 11 0.0014
665 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 23 0.0014
666 HEPATIC STEATOSIS 19 0.0014
667 EPISTAXIS 79 0.0014
668 ATAXIA 13 0.0014
669 INTERNATIONAL NORMALISED RATIO INCREASED 37 0.0014
670 ATRIAL FIBRILLATION 96 0.0014
671 METASTASES TO CENTRAL NERVOUS SYSTEM 11 0.0014
672 BODY TEMPERATURE DECREASED 10 0.0014
673 BLINDNESS 38 0.0014
674 FOOT FRACTURE 19 0.0014
675 UPPER GASTROINTESTINAL HAEMORRHAGE 18 0.0014
676 SUDDEN DEATH 12 0.0014
677 HYPOCALCAEMIA 18 0.0014
678 RENAL PAIN 10 0.0014
679 DISSEMINATED INTRAVASCULAR COAGULATION 15 0.0013
680 CARDIOMYOPATHY 15 0.0013
681 COLON CANCER 14 0.0013
682 PULMONARY ARTERIAL HYPERTENSION 15 0.0013
683 LACTIC ACIDOSIS 27 0.0013
684 PULMONARY EMBOLISM 99 0.0013
685 TRANSFUSION 10 0.0013
686 SPINAL PAIN 10 0.0013
687 ABDOMINAL PAIN 209 0.0013
688 TREATMENT NONCOMPLIANCE 43 0.0013
689 RENAL INJURY 34 0.0013
690 EOSINOPHILIA 15 0.0013
691 HYPERCALCAEMIA 11 0.0013
692 MASS 13 0.0013
693 NODULE 11 0.0013
694 PERITONITIS BACTERIAL 10 0.0012
695 COUGH 224 0.0012
696 MYOCARDIAL ISCHAEMIA 12 0.0012
697 ANGINA PECTORIS 28 0.0012
698 SINUS TACHYCARDIA 13 0.0012
699 THERAPEUTIC RESPONSE DECREASED 50 0.0012
700 GASTROINTESTINAL HAEMORRHAGE 85 0.0012
701 OXYGEN SATURATION DECREASED 41 0.0012
702 HIP FRACTURE 27 0.0012
703 APHONIA 11 0.0012
704 BLOOD POTASSIUM DECREASED 26 0.0012
705 DRUG-INDUCED LIVER INJURY 19 0.0012
706 HEPATIC FUNCTION ABNORMAL 29 0.0012
707 EPILEPSY 24 0.0012
708 RASH MACULO-PAPULAR 18 0.0012
709 CEREBRAL HAEMORRHAGE 32 0.0012
710 FREQUENT BOWEL MOVEMENTS 18 0.0012
711 INFLUENZA 84 0.0012
712 MUSCULOSKELETAL CHEST PAIN 13 0.0012
713 WEIGHT DECREASED 227 0.0012
714 PRODUCTIVE COUGH 34 0.0011
715 PANCREATITIS ACUTE 18 0.0011
716 RHINORRHOEA 47 0.0011
717 PLATELET COUNT INCREASED 10 0.0011
718 NEOPLASM PROGRESSION 25 0.0011
719 WHITE BLOOD CELL COUNT INCREASED 33 0.0011
720 SHOCK 18 0.0011
721 CARDIAC FAILURE CONGESTIVE 78 0.0011
722 HAEMATOCHEZIA 38 0.0011
723 MUSCULOSKELETAL DISCOMFORT 13 0.0011
724 NERVOUS SYSTEM DISORDER 28 0.0011
725 INTESTINAL OBSTRUCTION 27 0.0011
726 DIPLOPIA 20 0.0011
727 HYPONATRAEMIA 45 0.0011
728 CYSTITIS 26 0.0011
729 NASOPHARYNGITIS 130 0.0011
730 CYANOSIS 13 0.0011
731 PRODUCT DISPENSING ERROR 10 0.0011
732 SCAR 14 0.0011
733 ANOREXIA 14 0.0011
734 MUSCLE ATROPHY 9 0.0011
735 LOCALISED INFECTION 18 0.0011
736 DRY EYE 27 0.0011
737 CHILLS 89 0.0011
738 LOWER LIMB FRACTURE 13 0.0011
739 ECZEMA 19 0.0011
740 INTERNAL HAEMORRHAGE 9 0.0011
741 TREATMENT FAILURE 53 0.0010
742 DIVERTICULITIS 20 0.0010
743 CONVULSION 59 0.0010
744 BLOOD CREATINE PHOSPHOKINASE INCREASED 24 0.0010
745 PAIN 409 0.0010
746 DISCOMFORT 35 0.0010
747 MYOCLONUS 9 0.0010
748 VOMITING 329 0.0010
749 LETHARGY 43 0.0010
750 DERMATITIS 13 0.0010
751 EATING DISORDER 15 0.0010
752 NO THERAPEUTIC RESPONSE 12 0.0010
753 DEPRESSED LEVEL OF CONSCIOUSNESS 28 0.0010
754 HIATUS HERNIA 10 0.0010
755 LUNG NEOPLASM MALIGNANT 29 0.0010
756 HYPOPHAGIA 17 0.0010
757 DYSPHONIA 39 0.0010
758 BLOOD PRESSURE DECREASED 46 0.0010
759 GINGIVAL BLEEDING 9 0.0010
760 DYSPHAGIA 64 0.0010
761 GASTRIC HAEMORRHAGE 9 0.0010
762 SEIZURE 67 0.0010
763 UNRESPONSIVE TO STIMULI 18 0.0010
764 SINUS DISORDER 13 0.0010
765 DECREASED APPETITE 146 0.0010
766 ASTHENIA 252 0.0010
767 PREMATURE BABY 21 0.0009
768 THROMBOSIS 55 0.0009
769 INTRAOCULAR PRESSURE INCREASED 9 0.0009
770 PNEUMONIA ASPIRATION 16 0.0009
771 BONE PAIN 39 0.0009
772 HYPOTENSION 130 0.0009
773 OSTEOPOROSIS 27 0.0009
774 WOUND 14 0.0009
775 VENTRICULAR TACHYCARDIA 11 0.0009
776 BLOOD PRESSURE ABNORMAL 11 0.0009
777 NEUROPATHY PERIPHERAL 54 0.0009
778 SWELLING FACE 42 0.0009
779 ACUTE MYOCARDIAL INFARCTION 21 0.0009
780 NIGHT SWEATS 19 0.0009
781 FULL BLOOD COUNT DECREASED 11 0.0009
782 MYOCARDIAL INFARCTION 132 0.0009
783 BLOOD COUNT ABNORMAL 15 0.0009
784 MUSCULAR WEAKNESS 72 0.0009
785 DYSURIA 24 0.0009
786 EXPIRED PRODUCT ADMINISTERED 20 0.0009
787 STRESS 41 0.0009
788 CARDIOVASCULAR DISORDER 19 0.0009
789 EAR INFECTION 14 0.0009
790 LOWER RESPIRATORY TRACT INFECTION 24 0.0009
791 CATARACT 33 0.0009
792 COMA 30 0.0009
793 OVERDOSE 122 0.0009
794 RESPIRATORY ARREST 20 0.0009
795 CONFUSIONAL STATE 101 0.0009
796 CHOLELITHIASIS 21 0.0008
797 DYSPNOEA 339 0.0008
798 ABORTION SPONTANEOUS 26 0.0008
799 GLYCOSYLATED HAEMOGLOBIN INCREASED 14 0.0008
800 DEATH 484 0.0008
801 CEREBROVASCULAR ACCIDENT 111 0.0008
802 KIDNEY INFECTION 11 0.0008
803 DRUG INEFFECTIVE 738 0.0008
804 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 13 0.0008
805 DYSARTHRIA 23 0.0008
806 RASH PAPULAR 14 0.0008
807 MALIGNANT NEOPLASM PROGRESSION 51 0.0008
808 TREMOR 100 0.0008
809 DEMENTIA 14 0.0008
810 ABDOMINAL PAIN LOWER 15 0.0008
811 CENTRAL NERVOUS SYSTEM LESION 9 0.0008
812 OROPHARYNGEAL PAIN 49 0.0008
813 VISUAL ACUITY REDUCED 23 0.0008
814 CORONARY ARTERY OCCLUSION 9 0.0008
815 FACE OEDEMA 10 0.0008
816 COORDINATION ABNORMAL 9 0.0008
817 MALAISE 251 0.0008
818 BRONCHITIS 43 0.0008
819 JOINT SWELLING 59 0.0008
820 ABDOMINAL DISTENSION 55 0.0008
821 DRUG EXPOSURE DURING PREGNANCY 26 0.0008
822 HAEMORRHAGE 54 0.0008
823 ABDOMINAL DISCOMFORT 82 0.0007
824 TACHYCARDIA 47 0.0007
825 CIRCULATORY COLLAPSE 10 0.0007
826 HYPOGLYCAEMIA 27 0.0007
827 VISUAL IMPAIRMENT 58 0.0007
828 UPPER LIMB FRACTURE 11 0.0007
829 GASTROOESOPHAGEAL REFLUX DISEASE 41 0.0007
830 ACCIDENTAL OVERDOSE 18 0.0007
831 SINUSITIS 50 0.0007
832 SPEECH DISORDER 28 0.0007
833 AMNESIA 36 0.0007
834 THERAPEUTIC RESPONSE UNEXPECTED 24 0.0007
835 LACRIMATION INCREASED 13 0.0007
836 BLOOD PRESSURE INCREASED 75 0.0007
837 GASTRIC DISORDER 21 0.0007
838 RASH ERYTHEMATOUS 20 0.0007
839 INTENTIONAL PRODUCT MISUSE 41 0.0007
840 CHEST PAIN 95 0.0007
841 ORAL PAIN 11 0.0007
842 PROSTATE CANCER 35 0.0007
843 MYALGIA 82 0.0007
844 NAUSEA 366 0.0007
845 CARDIAC DISORDER 46 0.0007
846 DRUG HYPERSENSITIVITY 95 0.0007
847 COGNITIVE DISORDER 21 0.0007
848 NEUTROPHIL COUNT DECREASED 16 0.0006
849 HEADACHE 289 0.0006
850 URINARY RETENTION 15 0.0006
851 NASAL CONGESTION 23 0.0006
852 DIABETIC KETOACIDOSIS 11 0.0006
853 SWOLLEN TONGUE 15 0.0006
854 GAIT INABILITY 10 0.0006
855 LIP SWELLING 15 0.0006
856 LOCAL SWELLING 11 0.0006
857 LIMB DISCOMFORT 13 0.0006
858 APHASIA 14 0.0006
859 HAEMATEMESIS 12 0.0006
860 SWELLING 38 0.0006
861 CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR 9 0.0006
862 WEIGHT INCREASED 94 0.0006
863 MUSCULOSKELETAL STIFFNESS 36 0.0006
864 FATIGUE 313 0.0006
865 CARDIO-RESPIRATORY ARREST 20 0.0006
866 PAIN OF SKIN 12 0.0006
867 HYPOTHYROIDISM 12 0.0006
868 EYE DISORDER 13 0.0006
869 LIMB INJURY 10 0.0006
870 FALL 136 0.0006
871 VERTIGO 26 0.0006
872 CHEST DISCOMFORT 40 0.0006
873 POLLAKIURIA 17 0.0006
874 DRUG PRESCRIBING ERROR 11 0.0006
875 HYPOACUSIS 15 0.0006
876 ARTHROPATHY 21 0.0006
877 RASH 160 0.0006
878 FAECES DISCOLOURED 9 0.0006
879 CONTUSION 37 0.0006
880 BLOOD GLUCOSE INCREASED 80 0.0006
881 URINARY INCONTINENCE 12 0.0006
882 PAIN IN EXTREMITY 119 0.0006
883 PANCREATIC CARCINOMA 11 0.0005
884 HEART RATE INCREASED 38 0.0005
885 JOINT STIFFNESS 10 0.0005
886 SLEEP DISORDER 24 0.0005
887 SYSTEMIC LUPUS ERYTHEMATOSUS 10 0.0005
888 DISORIENTATION 17 0.0005
889 HOSPITALISATION 47 0.0005
890 TYPE 2 DIABETES MELLITUS 13 0.0005
891 TRANSIENT ISCHAEMIC ATTACK 14 0.0005
892 MUSCLE TWITCHING 9 0.0005
893 PRODUCT DOSE OMISSION 35 0.0005
894 DISTURBANCE IN ATTENTION 21 0.0005
895 ABDOMINAL PAIN UPPER 73 0.0005
896 BLISTER 19 0.0005
897 GAIT DISTURBANCE 70 0.0005
898 DEAFNESS 9 0.0005
899 ARTHRALGIA 131 0.0005
900 CEREBRAL INFARCTION 9 0.0005
901 ILLNESS 9 0.0005
902 RASH PRURITIC 17 0.0005
903 SURGERY 16 0.0005
904 DYSKINESIA 14 0.0005
905 MEDICATION ERROR 19 0.0005
906 RASH GENERALISED 12 0.0005
907 SKIN EXFOLIATION 25 0.0005
908 HALLUCINATION 23 0.0005
909 BLOOD GLUCOSE DECREASED 17 0.0005
910 ACTIVITIES OF DAILY LIVING IMPAIRED 9 0.0005
911 SKIN DISCOLOURATION 15 0.0005
912 PALPITATIONS 38 0.0005
913 HEAD INJURY 10 0.0005
914 ABASIA 11 0.0004
915 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 17 0.0004
916 PRURITUS 100 0.0004
917 ERYTHEMA 65 0.0004
918 INFLUENZA LIKE ILLNESS 28 0.0004
919 LOSS OF CONSCIOUSNESS 41 0.0004
920 ROAD TRAFFIC ACCIDENT 13 0.0004
921 DELIRIUM 10 0.0004
922 EXPOSURE DURING PREGNANCY 17 0.0004
923 DYSGEUSIA 23 0.0004
924 DYSSTASIA 9 0.0004
925 MEMORY IMPAIRMENT 41 0.0004
926 AGITATION 24 0.0004
927 DEPRESSION 73 0.0004
928 PARAESTHESIA 47 0.0004
929 HYPOAESTHESIA 44 0.0004
930 BRADYCARDIA 16 0.0004
931 COLITIS ULCERATIVE 9 0.0004
932 FEMUR FRACTURE 10 0.0004
933 MATERNAL EXPOSURE DURING PREGNANCY 19 0.0004
934 DIZZINESS 141 0.0004
935 PLASMA CELL MYELOMA 10 0.0004
936 EYE PAIN 13 0.0004
937 FLATULENCE 15 0.0004
938 VISION BLURRED 36 0.0004
939 OSTEOARTHRITIS 11 0.0004
940 RECTAL HAEMORRHAGE 12 0.0004
941 UNEVALUABLE EVENT 21 0.0004
942 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 24 0.0004
943 THERAPY CESSATION 12 0.0004
944 BACK PAIN 60 0.0004
945 ARRHYTHMIA 13 0.0004
946 ILL-DEFINED DISORDER 10 0.0004
947 IRRITABILITY 17 0.0004
948 CONSTIPATION 50 0.0004
949 MOBILITY DECREASED 17 0.0004
950 NECK PAIN 14 0.0004
951 DRY MOUTH 20 0.0004
952 DRUG EFFECT DECREASED 19 0.0004
953 MUSCULOSKELETAL PAIN 16 0.0004
954 BURNING SENSATION 18 0.0004
955 HYPERSENSITIVITY 45 0.0003
956 INSOMNIA 68 0.0003
957 ARTHRITIS 18 0.0003
958 EYE IRRITATION 11 0.0003
959 NERVOUSNESS 14 0.0003
960 NEPHROLITHIASIS 10 0.0003
961 PRODUCT SUBSTITUTION ISSUE 14 0.0003
962 SYNCOPE 24 0.0003
963 SOMNOLENCE 47 0.0003
964 MIGRAINE 20 0.0003
965 FEELING ABNORMAL 57 0.0003
966 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 10 0.0003
967 DRY SKIN 26 0.0003
968 BALANCE DISORDER 19 0.0003
969 MENTAL DISORDER 9 0.0003
970 INFUSION RELATED REACTION 11 0.0003
971 DRUG ADMINISTRATION ERROR 9 0.0003
972 HYPERHIDROSIS 27 0.0003
973 FEELING HOT 12 0.0003
974 ADVERSE EVENT 18 0.0003
975 DRUG DOSE OMISSION 45 0.0003
976 ADVERSE DRUG REACTION 14 0.0003
977 ABNORMAL BEHAVIOUR 9 0.0003
978 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 30 0.0003
979 ANXIETY 55 0.0003
980 PRODUCT DOSE OMISSION ISSUE 15 0.0003
981 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 18 0.0003
982 DYSPEPSIA 17 0.0003
983 MUSCLE SPASMS 33 0.0002
984 DRUG EFFECT INCOMPLETE 9 0.0002
985 BLADDER CANCER 10 0.0002
986 INCORRECT DOSE ADMINISTERED 28 0.0002
987 INJURY 14 0.0002
988 URTICARIA 27 0.0002
989 PRODUCT QUALITY ISSUE 27 0.0002
990 BREAST CANCER 17 0.0002
991 FOETAL EXPOSURE DURING PREGNANCY 13 0.0002
992 ASTHMA 15 0.0002
993 FLUSHING 17 0.0002
994 SUICIDAL IDEATION 14 0.0002
995 NO ADVERSE EVENT 19 0.0002
996 EMOTIONAL DISTRESS 11 0.0002