Antimetabolite Immunosuppressant [EPC]

Antimetabolite Immunosuppressant [EPC] was reported 8676 times

Drugs of the Antimetabolite Immunosuppressant [EPC] class are most commonly taken among patients reporting these side effects:

# Drug class Count Frequency
0 AORTIC PSEUDOANEURYSM 6 0.3158
1 HISTOPLASMOSIS CUTANEOUS 7 0.2917
2 DIABETIC MACROANGIOPATHY 8 0.2759
3 CUTANEOUS MALACOPLAKIA 7 0.2593
4 ANORECTAL VARICES 6 0.2308
5 NEW ONSET DIABETES AFTER TRANSPLANTATION 8 0.1702
6 GASTROINTESTINAL MUCORMYCOSIS 11 0.1692
7 MALACOPLAKIA GASTROINTESTINAL 11 0.1667
8 PASSENGER LYMPHOCYTE SYNDROME 6 0.1667
9 RHODOCOCCUS INFECTION 17 0.1650
10 MENINGOENCEPHALITIS AMOEBIC 6 0.1579
11 MALACOPLAKIA 15 0.1562
12 PARVOVIRUS B19 INFECTION 59 0.1549
13 GASTROENTERITIS SAPOVIRUS 8 0.1481
14 APOPTOSIS 34 0.1459
15 CHROMOBLASTOMYCOSIS 7 0.1373
16 URINOMA 16 0.1368
17 PHAEHYPHOMYCOSIS 19 0.1310
18 ISOSPORIASIS 8 0.1250
19 HUMAN EHRLICHIOSIS 15 0.1250
20 DONOR SPECIFIC ANTIBODY PRESENT 10 0.1235
21 ANTI-ERYTHROPOIETIN ANTIBODY NEGATIVE 9 0.1184
22 DISSEMINATED MUCORMYCOSIS 13 0.1140
23 PHAEOHYPHOMYCOSIS 26 0.1102
24 WEST NILE VIRAL INFECTION 48 0.0984
25 EPIDERMODYSPLASIA VERRUCIFORMIS 8 0.0964
26 PANCREAS TRANSPLANT REJECTION 15 0.0943
27 POLYOMAVIRUS-ASSOCIATED NEPHROPATHY 130 0.0937
28 POSTOPERATIVE THORACIC PROCEDURE COMPLICATION 7 0.0909
29 ALTERNARIA INFECTION 18 0.0874
30 CHRONIC ALLOGRAFT NEPHROPATHY 49 0.0852
31 POLYOMAVIRUS VIRAEMIA 32 0.0840
32 PNEUMOPERICARDIUM 10 0.0833
33 TRICHODYSPLASIA SPINULOSA 21 0.0817
34 RENAL TRANSPLANT FAILURE 50 0.0776
35 BACILLARY ANGIOMATOSIS 6 0.0750
36 DELAYED GRAFT FUNCTION 35 0.0738
37 PULMONARY MUCORMYCOSIS 13 0.0718
38 HEPATITIS E 72 0.0706
39 DISSEMINATED VARICELLA ZOSTER VIRUS INFECTION 8 0.0696
40 DISSEMINATED CRYPTOCOCCOSIS 28 0.0691
41 MUCOCUTANEOUS LEISHMANIASIS 6 0.0690
42 COMPLICATIONS OF TRANSPLANTED KIDNEY 122 0.0687
43 BLASTOMYCOSIS 17 0.0683
44 CYSTITIS VIRAL 13 0.0677
45 CHRONIC GRAFT VERSUS HOST DISEASE IN LIVER 15 0.0676
46 MENINGOENCEPHALITIS VIRAL 8 0.0640
47 AMERICAN TRYPANOSOMIASIS 11 0.0625
48 CHRONIC GRAFT VERSUS HOST DISEASE IN INTESTINE 7 0.0619
49 HERPES SIMPLEX OESOPHAGITIS 6 0.0619
50 GRAFT VERSUS HOST DISEASE IN LUNG 20 0.0599
51 HERPES SIMPLEX HEPATITIS 8 0.0597
52 SMOOTH MUSCLE CELL NEOPLASM 12 0.0577
53 POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER 173 0.0574
54 CYTOMEGALOVIRUS SYNDROME 7 0.0565
55 TRICHOPHYTOSIS 8 0.0563
56 PULMONARY NOCARDIOSIS 16 0.0556
57 INFECTION REACTIVATION 37 0.0555
58 TRANSPLANT DYSFUNCTION 70 0.0546
59 BK VIRUS INFECTION 107 0.0538
60 EPSTEIN-BARR VIRAEMIA 33 0.0537
61 GRAFT VERSUS HOST DISEASE IN LIVER 25 0.0523
62 MYCOBACTERIUM FORTUITUM INFECTION 6 0.0522
63 HEART TRANSPLANT REJECTION 43 0.0521
64 CRYPTOCOCCOSIS 52 0.0520
65 IMMUNOGLOBULIN G4 RELATED DISEASE 7 0.0519
66 UREAPLASMA INFECTION 9 0.0517
67 MICROSPORIDIA INFECTION 11 0.0512
68 HUMAN POLYOMAVIRUS INFECTION 18 0.0511
69 CYTOMEGALOVIRUS GASTRITIS 7 0.0507
70 KIDNEY TRANSPLANT REJECTION 195 0.0504
71 ADENOVIRAL HEPATITIS 7 0.0500
72 CYTOMEGALOVIRUS OESOPHAGITIS 12 0.0494
73 JC VIRUS INFECTION 51 0.0486
74 GRAFT VERSUS HOST DISEASE IN GASTROINTESTINAL TRACT 67 0.0482
75 CYTOMEGALOVIRUS GASTROENTERITIS 7 0.0479
76 CANDIDURIA 7 0.0470
77 ACANTHAMOEBA INFECTION 6 0.0469
78 DERMATOPHYTOSIS 10 0.0467
79 GRAFT VERSUS HOST DISEASE IN SKIN 69 0.0462
80 ALVEOLAR PROTEINOSIS 15 0.0460
81 CYTOMEGALOVIRUS VIRAEMIA 116 0.0455
82 ACID BASE BALANCE ABNORMAL 8 0.0452
83 GASTROINTESTINAL MUCOSA HYPERAEMIA 8 0.0449
84 GRAFT LOSS 27 0.0446
85 ANGIOSARCOMA 16 0.0443
86 SCEDOSPORIUM INFECTION 18 0.0439
87 RENAL TUBULAR ATROPHY 29 0.0433
88 CHEMICAL PERITONITIS 7 0.0424
89 TRANSPLANT REJECTION 237 0.0417
90 POST TRANSPLANT DISTAL LIMB SYNDROME 8 0.0415
91 CD8 LYMPHOCYTES DECREASED 7 0.0414
92 COMPLICATIONS OF TRANSPLANTED HEART 7 0.0414
93 CHRONIC HEPATITIS C 12 0.0392
94 HUMAN HERPESVIRUS 8 INFECTION 14 0.0391
95 AMAUROSIS FUGAX 23 0.0383
96 COMPLICATIONS OF TRANSPLANTED LUNG 7 0.0383
97 KIDNEY FIBROSIS 50 0.0380
98 CORYNEBACTERIUM INFECTION 13 0.0380
99 CHRONIC GRAFT VERSUS HOST DISEASE IN SKIN 20 0.0373
100 IMMUNOSUPPRESSANT DRUG LEVEL INCREASED 78 0.0373
101 ENCEPHALITIS CYTOMEGALOVIRUS 9 0.0370
102 RENAL TUBULAR INJURY 17 0.0364
103 PERIOSTITIS 12 0.0359
104 MUCORMYCOSIS 58 0.0339
105 LEISHMANIASIS 8 0.0339
106 ACUTE GRAFT VERSUS HOST DISEASE IN INTESTINE 32 0.0330
107 MORGANELLA INFECTION 7 0.0318
108 CAT SCRATCH DISEASE 7 0.0317
109 ACINETOBACTER INFECTION 25 0.0316
110 CEREBRAL ASPERGILLOSIS 14 0.0315
111 LUNG TRANSPLANT REJECTION 15 0.0314
112 CYTOMEGALOVIRUS INFECTION 374 0.0304
113 LYMPHOCELE 18 0.0303
114 PALPABLE PURPURA 6 0.0303
115 CYTOMEGALOVIRUS HEPATITIS 8 0.0302
116 VARICELLA ZOSTER VIRUS INFECTION 40 0.0299
117 VISCERAL LEISHMANIASIS 13 0.0297
118 CYTOMEGALOVIRUS GASTROINTESTINAL INFECTION 6 0.0296
119 SUPERINFECTION BACTERIAL 13 0.0294
120 CYTOMEGALOVIRUS COLITIS 40 0.0294
121 HISTOLOGY ABNORMAL 6 0.0290
122 PNEUMONIA PSEUDOMONAL 25 0.0288
123 FOCAL SEGMENTAL GLOMERULOSCLEROSIS 31 0.0282
124 GLOMERULONEPHRITIS PROLIFERATIVE 8 0.0275
125 PNEUMONIA CYTOMEGALOVIRAL 36 0.0272
126 ASPERGILLUS INFECTION 108 0.0272
127 LIVER TRANSPLANT REJECTION 39 0.0271
128 CHOROIDITIS 7 0.0271
129 HUMAN HERPESVIRUS 6 INFECTION 40 0.0271
130 GLOMERULONEPHRITIS MEMBRANOPROLIFERATIVE 10 0.0270
131 ANOGENITAL WARTS 18 0.0264
132 ENTEROVIRUS INFECTION 12 0.0260
133 STRONGYLOIDIASIS 29 0.0257
134 CRYPTOSPORIDIOSIS INFECTION 8 0.0255
135 ENCEPHALITIS VIRAL 23 0.0252
136 ADENOVIRUS INFECTION 46 0.0251
137 EPSTEIN-BARR VIRUS INFECTION 109 0.0246
138 RESPIRATORY TRACT INFLAMMATION 9 0.0246
139 NOCARDIOSIS 41 0.0242
140 BACTERIAL PYELONEPHRITIS 6 0.0241
141 IMMUNOSUPPRESSANT DRUG LEVEL DECREASED 22 0.0237
142 EPSTEIN-BARR VIRUS ASSOCIATED LYMPHOMA 8 0.0235
143 HISTOPLASMOSIS DISSEMINATED 21 0.0233
144 GASTROENTERITIS NOROVIRUS 25 0.0229
145 MEDIASTINITIS 9 0.0229
146 TRANSPLANT FAILURE 41 0.0225
147 CEREBRAL TOXOPLASMOSIS 13 0.0221
148 PNEUMONIA CRYPTOCOCCAL 12 0.0221
149 CENTRAL NERVOUS SYSTEM LYMPHOMA 19 0.0219
150 VIRAEMIA 18 0.0218
151 TOXOPLASMOSIS 18 0.0218
152 OBSTRUCTIVE PANCREATITIS 7 0.0218
153 THROMBOTIC MICROANGIOPATHY 133 0.0216
154 ENTEROBACTER INFECTION 26 0.0215
155 EPSTEIN-BARR VIRUS ASSOCIATED LYMPHOPROLIFERATIVE DISORDER 27 0.0215
156 PNEUMOCYSTIS JIROVECII INFECTION 13 0.0211
157 MYCOBACTERIUM ABSCESSUS INFECTION 8 0.0208
158 ACUTE GRAFT VERSUS HOST DISEASE IN LIVER 11 0.0208
159 CYSTITIS HAEMORRHAGIC 59 0.0204
160 HISTOPLASMOSIS 27 0.0199
161 SERRATIA INFECTION 11 0.0198
162 BRAIN ABSCESS 33 0.0195
163 CYTOMEGALOVIRUS INFECTION REACTIVATION 25 0.0188
164 VIRAL HAEMORRHAGIC CYSTITIS 7 0.0186
165 ATYPICAL HAEMOLYTIC URAEMIC SYNDROME 7 0.0186
166 APLASIA PURE RED CELL 48 0.0183
167 OBLITERATIVE BRONCHIOLITIS 19 0.0179
168 PYELONEPHRITIS ACUTE 26 0.0179
169 MYCOBACTERIAL INFECTION 23 0.0177
170 EPSTEIN-BARR VIRUS INFECTION REACTIVATION 7 0.0174
171 ABDOMINAL WALL ABSCESS 8 0.0172
172 LARGE INTESTINE INFECTION 8 0.0171
173 PAPILLOMA VIRAL INFECTION 20 0.0168
174 PNEUMOCYSTIS JIROVECII PNEUMONIA 103 0.0168
175 MYCOBACTERIUM CHELONAE INFECTION 8 0.0165
176 BRONCHOPULMONARY ASPERGILLOSIS 85 0.0165
177 HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS 45 0.0163
178 ENTEROCOCCAL INFECTION 55 0.0163
179 MENINGITIS CRYPTOCOCCAL 18 0.0159
180 GLOMERULOSCLEROSIS 8 0.0158
181 LISTERIOSIS 12 0.0155
182 PSEUDOMONAS INFECTION 89 0.0155
183 ACUTE GRAFT VERSUS HOST DISEASE IN SKIN 28 0.0153
184 CYTOMEGALOVIRUS CHORIORETINITIS 20 0.0152
185 KLEBSIELLA INFECTION 51 0.0151
186 ACUTE GRAFT VERSUS HOST DISEASE 52 0.0149
187 POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME 95 0.0149
188 PULMONARY CAVITATION 8 0.0147
189 INFECTION IN AN IMMUNOCOMPROMISED HOST 7 0.0146
190 LUPUS NEPHRITIS 14 0.0146
191 GRAFT VERSUS HOST DISEASE 80 0.0142
192 MICROANGIOPATHIC HAEMOLYTIC ANAEMIA 8 0.0141
193 MYOPATHY TOXIC 6 0.0139
194 OSMOTIC DEMYELINATION SYNDROME 7 0.0134
195 CHRONIC GRAFT VERSUS HOST DISEASE 35 0.0133
196 NEPHROPATHY TOXIC 97 0.0132
197 OESOPHAGEAL ATRESIA 7 0.0132
198 PNEUMONIA KLEBSIELLA 16 0.0130
199 ACARODERMATITIS 11 0.0130
200 STENOTROPHOMONAS INFECTION 11 0.0129
201 NEUROENDOCRINE CARCINOMA OF THE SKIN 8 0.0125
202 DIFFUSE LARGE B-CELL LYMPHOMA 53 0.0124
203 OROPHARYNGEAL CANDIDIASIS 8 0.0122
204 HERPES ZOSTER DISSEMINATED 6 0.0120
205 FUNGAL SEPSIS 8 0.0119
206 SECONDARY IMMUNODEFICIENCY 8 0.0114
207 PNEUMONIA INFLUENZAL 8 0.0113
208 VACCINATION FAILURE 8 0.0112
209 MENINGITIS BACTERIAL 12 0.0111
210 CHRONIC KIDNEY DISEASE-MINERAL AND BONE DISORDER 10 0.0110
211 ESCHERICHIA INFECTION 61 0.0110
212 DIARRHOEA INFECTIOUS 6 0.0109
213 DIFFUSE ALVEOLAR DAMAGE 10 0.0109
214 PRODUCT MONITORING ERROR 9 0.0109
215 COVID-19 PNEUMONIA 62 0.0107
216 REVERSIBLE CEREBRAL VASOCONSTRICTION SYNDROME 10 0.0104
217 HAEMOLYTIC URAEMIC SYNDROME 21 0.0104
218 HYPOGAMMAGLOBULINAEMIA 36 0.0103
219 MYCOBACTERIUM AVIUM COMPLEX INFECTION 17 0.0102
220 ILEAL ULCER 6 0.0101
221 IGA NEPHROPATHY 9 0.0101
222 LARGE INTESTINAL ULCER 20 0.0101
223 PULMONARY SEPSIS 10 0.0101
224 RENAL TUBULAR NECROSIS 73 0.0100
225 PNEUMOMEDIASTINUM 11 0.0099
226 BACTERIAL SEPSIS 24 0.0099
227 GINGIVAL HYPERTROPHY 9 0.0097
228 KLEBSIELLA SEPSIS 8 0.0097
229 PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY 60 0.0096
230 FANCONI SYNDROME 10 0.0095
231 DRUG LEVEL INCREASED 114 0.0095
232 OESOPHAGEAL STENOSIS 20 0.0095
233 HEPATIC FIBROSIS 23 0.0093
234 BLOOD IMMUNOGLOBULIN G DECREASED 11 0.0093
235 NECROTISING FASCIITIS 23 0.0093
236 CYTOMEGALOVIRUS TEST POSITIVE 12 0.0093
237 SYSTEMIC MYCOSIS 7 0.0093
238 NORMOCYTIC ANAEMIA 7 0.0090
239 DRUG LEVEL FLUCTUATING 6 0.0088
240 RENAL TUBULAR ACIDOSIS 13 0.0087
241 DISSEMINATED TUBERCULOSIS 16 0.0086
242 GLOMERULONEPHRITIS RAPIDLY PROGRESSIVE 6 0.0086
243 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME 32 0.0085
244 BRONCHIECTASIS 36 0.0085
245 WHITE MATTER LESION 7 0.0085
246 PNEUMATOSIS INTESTINALIS 16 0.0084
247 SOFT TISSUE DISORDER 8 0.0084
248 PELVIC VENOUS THROMBOSIS 10 0.0084
249 DISTRIBUTIVE SHOCK 6 0.0082
250 METASTATIC MALIGNANT MELANOMA 14 0.0082
251 HYPOCHROMIC ANAEMIA 6 0.0081
252 PNEUMOPERITONEUM 11 0.0081
253 SQUAMOUS CELL CARCINOMA OF SKIN 33 0.0080
254 BONE EROSION 18 0.0079
255 GENE MUTATION 10 0.0079
256 URINARY TRACT DISORDER 25 0.0079
257 CHOLANGITIS 32 0.0078
258 LYMPHOPROLIFERATIVE DISORDER 16 0.0078
259 RENAL TRANSPLANT 20 0.0078
260 PNEUMONIA FUNGAL 18 0.0078
261 BILE DUCT STENOSIS 7 0.0077
262 MULTIPLE ORGAN DYSFUNCTION SYNDROME 125 0.0077
263 BRADYARRHYTHMIA 10 0.0077
264 RENAL ARTERY STENOSIS 9 0.0077
265 NEUTROPENIC COLITIS 9 0.0074
266 PYELONEPHRITIS 46 0.0074
267 FUNGAEMIA 8 0.0074
268 FUNCTIONAL GASTROINTESTINAL DISORDER 19 0.0073
269 HISTIOCYTOSIS HAEMATOPHAGIC 22 0.0073
270 HYPERPARATHYROIDISM SECONDARY 16 0.0072
271 RHINOVIRUS INFECTION 13 0.0071
272 OESOPHAGEAL ULCER 22 0.0071
273 CD4 LYMPHOCYTES DECREASED 12 0.0068
274 EXTREMITY NECROSIS 9 0.0068
275 ACUTE RESPIRATORY DISTRESS SYNDROME 90 0.0068
276 OESOPHAGEAL CANDIDIASIS 19 0.0068
277 GENITAL HERPES 8 0.0067
278 CANDIDA INFECTION 72 0.0066
279 B-CELL LYMPHOMA 18 0.0066
280 LYMPHOPENIA 66 0.0066
281 SALMONELLOSIS 7 0.0066
282 LUNG CONSOLIDATION 14 0.0065
283 AZOTAEMIA 19 0.0065
284 GLOMERULONEPHRITIS 11 0.0064
285 ENCEPHALITIS 31 0.0064
286 BICYTOPENIA 7 0.0063
287 SYSTEMIC CANDIDA 10 0.0063
288 POSTOPERATIVE WOUND INFECTION 29 0.0062
289 CORONAVIRUS INFECTION 23 0.0061
290 CALCIPHYLAXIS 9 0.0060
291 PNEUMONIA LEGIONELLA 7 0.0059
292 FUNGAL SKIN INFECTION 17 0.0059
293 ESCHERICHIA URINARY TRACT INFECTION 19 0.0059
294 ANAL HAEMORRHAGE 12 0.0059
295 INTERMITTENT CLAUDICATION 8 0.0058
296 SKIN NECROSIS 24 0.0058
297 LEUKOPENIA 214 0.0058
298 CONCOMITANT DISEASE PROGRESSION 10 0.0056
299 NEPHRITIS 13 0.0056
300 COVID-19 381 0.0056
301 LIVER ABSCESS 13 0.0056
302 PLASMACYTOMA 8 0.0055
303 GLYCOSURIA 6 0.0054
304 PATHOGEN RESISTANCE 32 0.0054
305 PROTEINURIA 68 0.0054
306 URINARY TRACT INFECTION BACTERIAL 9 0.0054
307 ESCHERICHIA SEPSIS 12 0.0053
308 NEPHROGENIC ANAEMIA 22 0.0053
309 NEPHROTIC SYNDROME 27 0.0053
310 BILIARY DILATATION 6 0.0053
311 HYDRONEPHROSIS 29 0.0052
312 BRAIN HERNIATION 12 0.0052
313 PNEUMONIA VIRAL 11 0.0052
314 WOUND DEHISCENCE 14 0.0051
315 GRANULOMA 13 0.0051
316 HERPES SIMPLEX 24 0.0051
317 ENDOCARDITIS 19 0.0051
318 BONE MARROW TOXICITY 6 0.0050
319 ELECTROCARDIOGRAM ST SEGMENT DEPRESSION 9 0.0049
320 NOSOCOMIAL INFECTION 9 0.0049
321 SCLERODERMA 14 0.0049
322 END STAGE RENAL DISEASE 78 0.0049
323 NODAL RHYTHM 6 0.0049
324 ALVEOLITIS 6 0.0048
325 OPTIC ATROPHY 6 0.0048
326 ESCHERICHIA BACTERAEMIA 7 0.0048
327 GENERALISED OEDEMA 42 0.0048
328 HYPERLACTACIDAEMIA 8 0.0048
329 THROMBOCYTOSIS 12 0.0048
330 SEPTIC SHOCK 144 0.0048
331 SKIN PAPILLOMA 14 0.0048
332 BRAIN NATRIURETIC PEPTIDE INCREASED 10 0.0046
333 APLASTIC ANAEMIA 18 0.0046
334 LUNG ABSCESS 7 0.0045
335 HEPATITIS CHOLESTATIC 20 0.0045
336 STAPHYLOCOCCAL SEPSIS 18 0.0045
337 ENTEROCOLITIS 16 0.0045
338 BACTERAEMIA 35 0.0044
339 HAEMOLYTIC ANAEMIA 31 0.0044
340 VENOOCCLUSIVE LIVER DISEASE 15 0.0044
341 TUBULOINTERSTITIAL NEPHRITIS 59 0.0044
342 THROMBOTIC THROMBOCYTOPENIC PURPURA 13 0.0044
343 OLIGURIA 21 0.0043
344 HAEMODYNAMIC INSTABILITY 22 0.0043
345 OCULAR DISCOMFORT 25 0.0043
346 FANCONI SYNDROME ACQUIRED 6 0.0043
347 FIBROSIS 10 0.0042
348 SQUAMOUS CELL CARCINOMA 30 0.0042
349 DUODENITIS 10 0.0042
350 PANNICULITIS 7 0.0042
351 MYOPATHY 27 0.0041
352 SERUM SICKNESS 9 0.0041
353 STAPHYLOCOCCAL BACTERAEMIA 12 0.0041
354 RENAL IMPAIRMENT 241 0.0041
355 HEPATIC NECROSIS 13 0.0041
356 UROSEPSIS 27 0.0041
357 PROCTITIS 7 0.0040
358 PULMONARY ALVEOLAR HAEMORRHAGE 15 0.0040
359 CUSHINGOID 9 0.0040
360 BACTERIAL INFECTION 50 0.0040
361 ACUTE KIDNEY INJURY 410 0.0040
362 VENOOCCLUSIVE DISEASE 7 0.0039
363 HAEMORRHAGIC STROKE 25 0.0039
364 DRUG LEVEL ABOVE THERAPEUTIC 11 0.0039
365 CATATONIA 14 0.0039
366 HEPATITIS B REACTIVATION 8 0.0038
367 ARTERIAL THROMBOSIS 6 0.0038
368 HIDRADENITIS 12 0.0037
369 CLOSTRIDIUM DIFFICILE COLITIS 29 0.0037
370 CEREBRAL ATROPHY 12 0.0037
371 PANCYTOPENIA 150 0.0037
372 SYSTEMIC INFLAMMATORY RESPONSE SYNDROME 11 0.0037
373 DRUG LEVEL DECREASED 24 0.0037
374 DERMATOMYOSITIS 6 0.0036
375 HYPERCALCAEMIA 33 0.0036
376 EMBOLISM VENOUS 8 0.0036
377 LARGE INTESTINE PERFORATION 19 0.0036
378 HEPATIC ENCEPHALOPATHY 26 0.0036
379 LYMPHADENITIS 6 0.0036
380 DRUG RESISTANCE 62 0.0036
381 ORGANISING PNEUMONIA 11 0.0035
382 BLOOD CREATININE INCREASED 176 0.0035
383 RESPIRATORY FAILURE 196 0.0035
384 ABDOMINAL INFECTION 6 0.0034
385 BLOOD CREATINE INCREASED 11 0.0034
386 PERIORBITAL SWELLING 7 0.0034
387 PULSELESS ELECTRICAL ACTIVITY 10 0.0034
388 DEAFNESS NEUROSENSORY 8 0.0034
389 ODYNOPHAGIA 14 0.0033
390 HYPERTRIGLYCERIDAEMIA 14 0.0033
391 IMPULSIVE BEHAVIOUR 10 0.0033
392 PNEUMONIA BACTERIAL 18 0.0033
393 GUILLAIN-BARRE SYNDROME 11 0.0033
394 DISEASE RECURRENCE 57 0.0033
395 METABOLIC ACIDOSIS 72 0.0033
396 PRODUCT USE IN UNAPPROVED INDICATION 434 0.0033
397 CLOSTRIDIAL INFECTION 10 0.0032
398 NEUROTOXICITY 37 0.0032
399 INFLAMMATORY MARKER INCREASED 9 0.0032
400 PNEUMOCYSTIS JIROVECI PNEUMONIA 7 0.0031
401 ELECTROLYTE IMBALANCE 25 0.0031
402 HYPERKALAEMIA 82 0.0031
403 ENTERITIS 13 0.0031
404 METASTASES TO SPINE 7 0.0031
405 ASCITES 68 0.0031
406 NEUTROPENIA 270 0.0030
407 PULMONARY MASS 31 0.0030
408 ABSCESS LIMB 9 0.0030
409 BRAIN DEATH 7 0.0030
410 ENCEPHALOPATHY 52 0.0030
411 PEMPHIGOID 14 0.0029
412 HYPOALBUMINAEMIA 16 0.0029
413 AUTOIMMUNE HEPATITIS 14 0.0029
414 GASTROINTESTINAL PERFORATION 9 0.0029
415 PULMONARY FUNCTION TEST DECREASED 10 0.0029
416 HYDROCEPHALUS 12 0.0029
417 MYELOSUPPRESSION 18 0.0029
418 CREPITATIONS 7 0.0029
419 MENINGITIS 14 0.0029
420 ANURIA 20 0.0028
421 SEPSIS 234 0.0028
422 HEART VALVE INCOMPETENCE 6 0.0028
423 DRUG INTERACTION 336 0.0028
424 MYOSITIS 17 0.0028
425 AGRANULOCYTOSIS 34 0.0028
426 NEPHROPATHY 21 0.0028
427 MALIGNANT MELANOMA 28 0.0028
428 LUNG ADENOCARCINOMA 6 0.0028
429 DYSLIPIDAEMIA 10 0.0028
430 CYTOPENIA 16 0.0027
431 NECROSIS 12 0.0027
432 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 23 0.0027
433 TUBERCULOSIS 25 0.0027
434 ACUTE HEPATIC FAILURE 26 0.0027
435 COLITIS 65 0.0027
436 HYPERURICAEMIA 8 0.0026
437 CHRONIC MYELOID LEUKAEMIA 9 0.0026
438 C-REACTIVE PROTEIN ABNORMAL 8 0.0026
439 PEMPHIGUS 17 0.0025
440 NORMOCHROMIC NORMOCYTIC ANAEMIA 6 0.0025
441 DIARRHOEA HAEMORRHAGIC 17 0.0025
442 TOXIC ENCEPHALOPATHY 8 0.0025
443 TRANSAMINASES INCREASED 42 0.0025
444 LUNG INFILTRATION 19 0.0024
445 SMALL INTESTINAL OBSTRUCTION 22 0.0024
446 INTESTINAL ISCHAEMIA 10 0.0024
447 SUBCUTANEOUS ABSCESS 9 0.0024
448 GASTROENTERITIS 26 0.0024
449 THERAPY PARTIAL RESPONDER 10 0.0024
450 DUODENAL ULCER 13 0.0024
451 HEPATOTOXICITY 36 0.0024
452 CORONARY ARTERY STENOSIS 10 0.0024
453 BASAL CELL CARCINOMA 27 0.0024
454 HAEMATURIA 66 0.0024
455 CACHEXIA 9 0.0023
456 HERPES VIRUS INFECTION 10 0.0023
457 PAPILLOEDEMA 8 0.0023
458 PULMONARY TUBERCULOSIS 8 0.0023
459 MYOCARDITIS 15 0.0023
460 WOUND INFECTION 15 0.0023
461 ABNORMAL LOSS OF WEIGHT 12 0.0023
462 MULTI-ORGAN FAILURE 40 0.0023
463 LEUKOCYTOSIS 31 0.0023
464 BRAIN OEDEMA 22 0.0023
465 APHTHOUS ULCER 10 0.0023
466 PRE-ECLAMPSIA 8 0.0023
467 IMMUNOSUPPRESSION 12 0.0022
468 LABELLED DRUG-DRUG INTERACTION MEDICATION ERROR 16 0.0022
469 ALTERED STATE OF CONSCIOUSNESS 33 0.0022
470 RED BLOOD CELL SEDIMENTATION RATE INCREASED 18 0.0022
471 HYPERKERATOSIS 9 0.0022
472 HYPOVOLAEMIA 10 0.0022
473 GENERALISED TONIC-CLONIC SEIZURE 24 0.0022
474 ANGIOPATHY 10 0.0022
475 ATELECTASIS 17 0.0022
476 LUNG INFECTION 34 0.0022
477 GASTROINTESTINAL TOXICITY 6 0.0022
478 ATRIOVENTRICULAR BLOCK COMPLETE 11 0.0022
479 NON-CARDIAC CHEST PAIN 6 0.0022
480 RESPIRATORY DISTRESS 46 0.0021
481 ENDOPHTHALMITIS 9 0.0021
482 LARGE INTESTINE POLYP 11 0.0021
483 HEAD DISCOMFORT 25 0.0021
484 DISSEMINATED INTRAVASCULAR COAGULATION 24 0.0021
485 HYPOXIA 54 0.0021
486 STAPHYLOCOCCAL INFECTION 55 0.0021
487 HYPOTONIA 17 0.0021
488 ACUTE CORONARY SYNDROME 14 0.0021
489 BRONCHOPNEUMONIA 7 0.0020
490 IRON DEFICIENCY ANAEMIA 14 0.0020
491 POLYARTHRITIS 7 0.0020
492 OESOPHAGITIS 17 0.0020
493 MOUTH ULCERATION 30 0.0020
494 INTERSTITIAL LUNG DISEASE 68 0.0020
495 HEPATIC FAILURE 48 0.0020
496 COMA 75 0.0020
497 METASTASIS 10 0.0020
498 PHOTOPHOBIA 26 0.0020
499 CARDIOTOXICITY 11 0.0020
500 ARTHRITIS BACTERIAL 6 0.0020
501 ECCHYMOSIS 11 0.0020
502 HYPERAMMONAEMIA 7 0.0020
503 HELICOBACTER INFECTION 9 0.0020
504 INTRACRANIAL PRESSURE INCREASED 8 0.0019
505 HEPATITIS C 21 0.0019
506 NEUROLOGICAL SYMPTOM 8 0.0019
507 PROTEIN URINE PRESENT 7 0.0019
508 ACUTE RESPIRATORY FAILURE 25 0.0019
509 ORAL HERPES 24 0.0019
510 OFF LABEL USE 889 0.0019
511 ORAL CANDIDIASIS 17 0.0019
512 PNEUMONIA ASPIRATION 34 0.0019
513 PNEUMONITIS 33 0.0019
514 ANEURYSM 7 0.0018
515 FEBRILE NEUTROPENIA 82 0.0018
516 RALES 8 0.0018
517 SKIN LESION 35 0.0018
518 SHOCK 30 0.0018
519 HYPOMAGNESAEMIA 17 0.0018
520 SYSTEMIC LUPUS ERYTHEMATOSUS 37 0.0018
521 DRUG INTOLERANCE 120 0.0018
522 CENTRAL NERVOUS SYSTEM LESION 21 0.0018
523 C-REACTIVE PROTEIN INCREASED 44 0.0018
524 LEFT VENTRICULAR HYPERTROPHY 6 0.0018
525 METASTASES TO LUNG 14 0.0018
526 HAEMATOMA 37 0.0018
527 GLOMERULAR FILTRATION RATE DECREASED 13 0.0018
528 DRUG LEVEL BELOW THERAPEUTIC 6 0.0018
529 INTENTIONAL PRODUCT USE ISSUE 89 0.0018
530 PLATELET COUNT ABNORMAL 7 0.0017
531 CLOSTRIDIUM DIFFICILE INFECTION 25 0.0017
532 DIVERTICULUM 11 0.0017
533 BONE MARROW FAILURE 31 0.0017
534 MYASTHENIA GRAVIS 6 0.0017
535 FUNGAL INFECTION 41 0.0017
536 FLUID OVERLOAD 25 0.0017
537 JOINT EFFUSION 9 0.0017
538 HYPERTHERMIA 10 0.0017
539 HAEMOLYSIS 10 0.0017
540 TREATMENT FAILURE 89 0.0017
541 HEMIPARESIS 23 0.0017
542 HEPATITIS B 8 0.0017
543 HYPERGLYCAEMIA 46 0.0016
544 MUCOSAL INFLAMMATION 31 0.0016
545 SKIN PLAQUE 9 0.0016
546 RENAL FAILURE 179 0.0016
547 FAECES SOFT 6 0.0016
548 ARTERIOSCLEROSIS 12 0.0016
549 CHOLESTASIS 22 0.0016
550 SYNOVITIS 17 0.0016
551 LOWER GASTROINTESTINAL HAEMORRHAGE 10 0.0016
552 REBOUND EFFECT 9 0.0016
553 TACHYPNOEA 15 0.0016
554 OSTEOMYELITIS 23 0.0016
555 PERITONITIS 26 0.0016
556 METASTASES TO LYMPH NODES 7 0.0016
557 ACUTE PULMONARY OEDEMA 7 0.0016
558 WALKING AID USER 7 0.0016
559 UPPER RESPIRATORY TRACT INFECTION 52 0.0016
560 TOXICITY TO VARIOUS AGENTS 181 0.0015
561 STATUS EPILEPTICUS 13 0.0015
562 PANCREATITIS ACUTE 25 0.0015
563 DIABETES MELLITUS 92 0.0015
564 MENTAL STATUS CHANGES 33 0.0015
565 ABSCESS 17 0.0015
566 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 11 0.0015
567 UVEITIS 12 0.0015
568 PNEUMOTHORAX 17 0.0015
569 RESPIRATORY TRACT INFECTION 26 0.0015
570 CHRONIC KIDNEY DISEASE 98 0.0015
571 MASS 16 0.0015
572 DIPLOPIA 28 0.0015
573 VASCULITIS 12 0.0015
574 CARDIOGENIC SHOCK 14 0.0015
575 PERIPHERAL SENSORY NEUROPATHY 6 0.0015
576 PLEURAL EFFUSION 68 0.0015
577 DEVICE RELATED INFECTION 18 0.0015
578 GASTROINTESTINAL DISORDER 79 0.0014
579 RENAL FAILURE CHRONIC 11 0.0014
580 FAILURE TO THRIVE 6 0.0014
581 HYPERLIPIDAEMIA 14 0.0014
582 HAEMATOTOXICITY 8 0.0014
583 LACTIC ACIDOSIS 30 0.0014
584 HAEMATEMESIS 28 0.0014
585 MALNUTRITION 11 0.0014
586 SCIATICA 14 0.0014
587 THERAPY NON-RESPONDER 33 0.0014
588 PRESYNCOPE 24 0.0014
589 ACIDOSIS 8 0.0014
590 THROMBOCYTOPENIA 108 0.0014
591 BLINDNESS 39 0.0013
592 DIVERTICULITIS 27 0.0013
593 ULCER 16 0.0013
594 CARDIAC FAILURE ACUTE 6 0.0013
595 GASTRIC ULCER 20 0.0013
596 HERPES ZOSTER 57 0.0013
597 EOSINOPHILIA 16 0.0013
598 HYPONATRAEMIA 55 0.0013
599 ANAEMIA 186 0.0013
600 BLOOD UREA INCREASED 18 0.0013
601 COAGULOPATHY 17 0.0013
602 PYREXIA 325 0.0013
603 INFLAMMATION 43 0.0013
604 CARDIAC ARREST 84 0.0013
605 ORAL DISORDER 7 0.0013
606 IMPAIRED HEALING 29 0.0013
607 HEPATIC CIRRHOSIS 16 0.0012
608 LIVER FUNCTION TEST ABNORMAL 31 0.0012
609 PULMONARY HYPERTENSION 20 0.0012
610 HEPATOCELLULAR CARCINOMA 7 0.0012
611 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 40 0.0012
612 HYPOPHOSPHATAEMIA 6 0.0012
613 INTESTINAL PERFORATION 10 0.0012
614 QUALITY OF LIFE DECREASED 12 0.0012
615 LYMPHADENOPATHY 31 0.0012
616 URINARY TRACT INFECTION 141 0.0012
617 PERICARDITIS 10 0.0012
618 BLOOD DISORDER 7 0.0012
619 EYE PAIN 42 0.0012
620 SUBARACHNOID HAEMORRHAGE 9 0.0012
621 DELUSION 13 0.0012
622 HYPOTHERMIA 9 0.0012
623 HYPERCHOLESTEROLAEMIA 7 0.0011
624 BLOOD ALBUMIN DECREASED 7 0.0011
625 MUSCLE ATROPHY 10 0.0011
626 TREATMENT NONCOMPLIANCE 40 0.0011
627 PNEUMONIA 258 0.0011
628 AORTIC ANEURYSM 7 0.0011
629 LIVER INJURY 15 0.0011
630 DRUG-INDUCED LIVER INJURY 19 0.0011
631 GASTRITIS 22 0.0011
632 PERITONITIS BACTERIAL 9 0.0011
633 PULMONARY HAEMORRHAGE 7 0.0011
634 INTRAOCULAR PRESSURE INCREASED 11 0.0011
635 HYPERBILIRUBINAEMIA 8 0.0011
636 RENAL FAILURE ACUTE 46 0.0011
637 CONDITION AGGRAVATED 202 0.0011
638 BLOOD LACTATE DEHYDROGENASE INCREASED 14 0.0011
639 ISCHAEMIC STROKE 15 0.0011
640 PARALYSIS 12 0.0011
641 IMPAIRED GASTRIC EMPTYING 6 0.0011
642 BLOOD BILIRUBIN INCREASED 23 0.0011
643 EYE INFLAMMATION 6 0.0011
644 IMMUNODEFICIENCY 9 0.0011
645 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 38 0.0011
646 OSTEOPOROSIS 33 0.0011
647 PHARYNGITIS 10 0.0011
648 PSORIATIC ARTHROPATHY 23 0.0010
649 DIABETES MELLITUS INADEQUATE CONTROL 14 0.0010
650 SKIN INFECTION 8 0.0010
651 SKIN ULCER 20 0.0010
652 NEUTROPHIL COUNT INCREASED 8 0.0010
653 PRODUCT PRESCRIBING ERROR 13 0.0010
654 RASH MACULO-PAPULAR 16 0.0010
655 LIPASE INCREASED 6 0.0010
656 HAEMOPTYSIS 22 0.0010
657 MITRAL VALVE INCOMPETENCE 9 0.0010
658 HAEMOGLOBIN DECREASED 79 0.0010
659 CARDIO-RESPIRATORY ARREST 35 0.0010
660 INTERNAL HAEMORRHAGE 9 0.0010
661 PURPURA 7 0.0010
662 HAEMORRHOIDS 15 0.0010
663 ILEUS 9 0.0010
664 INFECTION 97 0.0010
665 URINE OUTPUT DECREASED 7 0.0010
666 LUNG DISORDER 34 0.0010
667 METASTASES TO LIVER 12 0.0010
668 IMMUNE SYSTEM DISORDER 9 0.0010
669 CARDIOMYOPATHY 11 0.0010
670 HEPATITIS 18 0.0009
671 CEREBRAL INFARCTION 18 0.0009
672 TACHYCARDIA 62 0.0009
673 MATERNAL EXPOSURE DURING PREGNANCY 49 0.0009
674 BRADYCARDIA 39 0.0009
675 DIARRHOEA 411 0.0009
676 PULMONARY CONGESTION 9 0.0009
677 BLOOD IRON DECREASED 7 0.0009
678 GENERAL PHYSICAL HEALTH DETERIORATION 68 0.0009
679 INFUSION RELATED REACTION 38 0.0009
680 THERAPY INTERRUPTED 18 0.0009
681 HEMIPLEGIA 6 0.0009
682 CELLULITIS 35 0.0009
683 TENDON RUPTURE 9 0.0009
684 SPLENOMEGALY 8 0.0009
685 MYELODYSPLASTIC SYNDROME 10 0.0009
686 PRODUCTIVE COUGH 28 0.0009
687 ASPIRATION 7 0.0009
688 HEPATIC FUNCTION ABNORMAL 23 0.0009
689 THERAPEUTIC RESPONSE DECREASED 38 0.0009
690 BLOOD POTASSIUM INCREASED 11 0.0009
691 INFLAMMATORY BOWEL DISEASE 7 0.0009
692 DYSURIA 25 0.0009
693 DERMATITIS 12 0.0009
694 HEPATOMEGALY 7 0.0009
695 MYOCLONUS 8 0.0009
696 OSTEOPENIA 10 0.0009
697 DISEASE PROGRESSION 68 0.0009
698 PULMONARY OEDEMA 30 0.0009
699 ABDOMINAL PAIN 147 0.0009
700 DYSPNOEA EXERTIONAL 22 0.0009
701 BLOOD SODIUM DECREASED 12 0.0009
702 APHASIA 20 0.0009
703 URINARY RETENTION 21 0.0009
704 LYMPHOCYTE COUNT DECREASED 11 0.0009
705 BLOOD PRESSURE FLUCTUATION 15 0.0008
706 ADRENAL INSUFFICIENCY 6 0.0008
707 METASTASES TO CENTRAL NERVOUS SYSTEM 7 0.0008
708 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 22 0.0008
709 HYPOPHAGIA 15 0.0008
710 ABORTION SPONTANEOUS 26 0.0008
711 RENAL INJURY 22 0.0008
712 VIRAL INFECTION 18 0.0008
713 BODY TEMPERATURE DECREASED 6 0.0008
714 CARDIAC FAILURE 47 0.0008
715 HEPATIC ENZYME INCREASED 37 0.0008
716 DIABETIC KETOACIDOSIS 14 0.0008
717 GASTROOESOPHAGEAL REFLUX DISEASE 45 0.0008
718 TINNITUS 26 0.0008
719 GASTROINTESTINAL HAEMORRHAGE 54 0.0008
720 CEREBRAL HAEMORRHAGE 21 0.0008
721 BLOOD PRESSURE SYSTOLIC INCREASED 10 0.0008
722 CHILLS 65 0.0008
723 HAEMODIALYSIS 6 0.0008
724 MELAENA 13 0.0007
725 ATRIAL FIBRILLATION 53 0.0007
726 BLOOD COUNT ABNORMAL 12 0.0007
727 PERICARDIAL EFFUSION 12 0.0007
728 HYPERTENSION 109 0.0007
729 LIVER FUNCTION TEST INCREASED 9 0.0007
730 INTESTINAL OBSTRUCTION 18 0.0007
731 OEDEMA PERIPHERAL 70 0.0007
732 MANIA 9 0.0007
733 PREMATURE DELIVERY 8 0.0007
734 GLAUCOMA 10 0.0007
735 OXYGEN SATURATION DECREASED 25 0.0007
736 HALLUCINATION, AUDITORY 8 0.0007
737 AMENORRHOEA 9 0.0007
738 COUGH 129 0.0007
739 JAUNDICE 15 0.0007
740 UNRESPONSIVE TO STIMULI 13 0.0007
741 DRUG EFFECTIVE FOR UNAPPROVED INDICATION 7 0.0007
742 GASTROENTERITIS VIRAL 8 0.0007
743 NODULE 6 0.0007
744 CYSTITIS 16 0.0006
745 HEPATOCELLULAR INJURY 8 0.0006
746 KIDNEY INFECTION 9 0.0006
747 VENTRICULAR TACHYCARDIA 8 0.0006
748 LOWER RESPIRATORY TRACT INFECTION 19 0.0006
749 RENAL DISORDER 22 0.0006
750 ANGINA PECTORIS 15 0.0006
751 BLOOD TEST ABNORMAL 6 0.0006
752 SKIN DISORDER 14 0.0006
753 HYPOTENSION 94 0.0006
754 RASH ERYTHEMATOUS 19 0.0006
755 CATARACT 26 0.0006
756 PULMONARY FIBROSIS 8 0.0006
757 DELIRIUM 15 0.0006
758 LYMPHOMA 7 0.0006
759 MYOCARDIAL ISCHAEMIA 6 0.0006
760 SCAR 8 0.0006
761 PULMONARY ARTERIAL HYPERTENSION 7 0.0006
762 OSTEONECROSIS 17 0.0006
763 DEHYDRATION 61 0.0006
764 ANAPHYLACTIC REACTION 22 0.0006
765 BLOOD PRESSURE INCREASED 67 0.0006
766 GAIT INABILITY 11 0.0006
767 SEIZURE 44 0.0006
768 RED BLOOD CELL COUNT DECREASED 12 0.0006
769 DEAFNESS 11 0.0006
770 HEPATIC STEATOSIS 8 0.0006
771 WEIGHT DECREASED 118 0.0006
772 PANCREATITIS 24 0.0006
773 HIATUS HERNIA 6 0.0006
774 DEPRESSED LEVEL OF CONSCIOUSNESS 17 0.0006
775 CARDIOMEGALY 6 0.0006
776 MUSCULAR WEAKNESS 48 0.0006
777 PLATELET COUNT DECREASED 43 0.0006
778 DEEP VEIN THROMBOSIS 31 0.0006
779 HALLUCINATION, VISUAL 8 0.0006
780 LIVER DISORDER 18 0.0006
781 HAEMORRHAGE INTRACRANIAL 7 0.0006
782 JOINT SWELLING 45 0.0006
783 MYALGIA 70 0.0005
784 ABDOMINAL PAIN UPPER 81 0.0005
785 CHOLELITHIASIS 14 0.0005
786 HAEMORRHAGE 41 0.0005
787 SKIN CANCER 8 0.0005
788 VOMITING 185 0.0005
789 HYPOKALAEMIA 18 0.0005
790 RESPIRATORY DISORDER 12 0.0005
791 SOMNOLENCE 81 0.0005
792 BRONCHOSPASM 6 0.0005
793 POST PROCEDURAL COMPLICATION 8 0.0005
794 SINUSITIS 39 0.0005
795 JOINT STIFFNESS 10 0.0005
796 ACUTE MYELOID LEUKAEMIA 6 0.0005
797 DIALYSIS 6 0.0005
798 EPILEPSY 11 0.0005
799 THERAPEUTIC PRODUCT EFFECT DECREASED 12 0.0005
800 ECZEMA 10 0.0005
801 CORONARY ARTERY OCCLUSION 6 0.0005
802 PRODUCT USE ISSUE 65 0.0005
803 ABDOMINAL PAIN LOWER 10 0.0005
804 OEDEMA 20 0.0005
805 TREMOR 65 0.0005
806 CIRCULATORY COLLAPSE 7 0.0005
807 ARTHRITIS 28 0.0005
808 COGNITIVE DISORDER 17 0.0005
809 DRUG INEFFECTIVE 471 0.0005
810 ALANINE AMINOTRANSFERASE INCREASED 24 0.0005
811 SYNCOPE 38 0.0005
812 CONTRAINDICATED PRODUCT ADMINISTERED 9 0.0005
813 HAEMATOCHEZIA 18 0.0005
814 HAEMATOCRIT DECREASED 8 0.0005
815 DYSPNOEA 203 0.0005
816 ECONOMIC PROBLEM 7 0.0005
817 PSYCHOTIC DISORDER 11 0.0005
818 BLOOD URINE PRESENT 7 0.0005
819 ACCIDENTAL OVERDOSE 12 0.0005
820 FOETAL EXPOSURE DURING PREGNANCY 27 0.0005
821 LOCALISED INFECTION 8 0.0005
822 WHITE BLOOD CELL COUNT DECREASED 35 0.0005
823 INTERNATIONAL NORMALISED RATIO INCREASED 12 0.0005
824 ABDOMINAL DISCOMFORT 53 0.0005
825 DISCOMFORT 17 0.0005
826 VISION BLURRED 45 0.0005
827 ANHEDONIA 10 0.0005
828 DYSPEPSIA 32 0.0005
829 RASH PAPULAR 8 0.0005
830 INFLUENZA 33 0.0004
831 STEVENS-JOHNSON SYNDROME 8 0.0004
832 PERIPHERAL SWELLING 45 0.0004
833 BODY TEMPERATURE INCREASED 7 0.0004
834 BLOOD ALKALINE PHOSPHATASE INCREASED 9 0.0004
835 ASTHENIA 121 0.0004
836 HYPOCALCAEMIA 6 0.0004
837 DISORIENTATION 14 0.0004
838 ARRHYTHMIA 16 0.0004
839 PULMONARY EMBOLISM 33 0.0004
840 NAUSEA 242 0.0004
841 THROMBOSIS 26 0.0004
842 GASTRIC DISORDER 13 0.0004
843 CONFUSIONAL STATE 51 0.0004
844 COLITIS ULCERATIVE 10 0.0004
845 DECREASED APPETITE 66 0.0004
846 ASPARTATE AMINOTRANSFERASE INCREASED 17 0.0004
847 WHEEZING 16 0.0004
848 MUSCULOSKELETAL PAIN 19 0.0004
849 SKIN DISCOLOURATION 14 0.0004
850 NIGHT SWEATS 9 0.0004
851 ABDOMINAL DISTENSION 30 0.0004
852 THERAPEUTIC RESPONSE UNEXPECTED 14 0.0004
853 BLISTER 16 0.0004
854 HEADACHE 184 0.0004
855 HYPOGLYCAEMIA 15 0.0004
856 DYSKINESIA 12 0.0004
857 RECTAL HAEMORRHAGE 13 0.0004
858 EXPOSURE DURING PREGNANCY 16 0.0004
859 ELECTROCARDIOGRAM QT PROLONGED 10 0.0004
860 OROPHARYNGEAL PAIN 24 0.0004
861 DRY EYE 10 0.0004
862 SWELLING 24 0.0004
863 LOSS OF CONSCIOUSNESS 36 0.0004
864 DYSPHAGIA 25 0.0004
865 NEUROPATHY PERIPHERAL 23 0.0004
866 PAIN IN JAW 8 0.0004
867 FATIGUE 193 0.0004
868 LETHARGY 16 0.0004
869 RHEUMATOID ARTHRITIS 28 0.0003
870 BLOOD CHOLESTEROL INCREASED 12 0.0003
871 ARTHRALGIA 97 0.0003
872 NEPHROLITHIASIS 11 0.0003
873 NERVOUS SYSTEM DISORDER 9 0.0003
874 PREMATURE BABY 8 0.0003
875 NASAL CONGESTION 13 0.0003
876 ILL-DEFINED DISORDER 10 0.0003
877 PRODUCT DOSE OMISSION ISSUE 28 0.0003
878 BLOOD CREATINE PHOSPHOKINASE INCREASED 8 0.0003
879 WHITE BLOOD CELL COUNT INCREASED 10 0.0003
880 RASH MACULAR 8 0.0003
881 PLASMA CELL MYELOMA 9 0.0003
882 MENTAL DISORDER 11 0.0003
883 PSORIASIS 31 0.0003
884 BRONCHITIS 19 0.0003
885 GAMMA-GLUTAMYLTRANSFERASE INCREASED 6 0.0003
886 LIMB INJURY 6 0.0003
887 MUSCULOSKELETAL STIFFNESS 21 0.0003
888 MENTAL IMPAIRMENT 6 0.0003
889 SUICIDE ATTEMPT 15 0.0003
890 DEPRESSED MOOD 12 0.0003
891 RHABDOMYOLYSIS 10 0.0003
892 CHEST DISCOMFORT 23 0.0003
893 ADVERSE DRUG REACTION 17 0.0003
894 DYSARTHRIA 9 0.0003
895 SWELLING FACE 15 0.0003
896 INSOMNIA 62 0.0003
897 CONVULSION 17 0.0003
898 RASH 88 0.0003
899 SPEECH DISORDER 12 0.0003
900 CHEST PAIN 42 0.0003
901 RHINORRHOEA 13 0.0003
902 MOOD ALTERED 6 0.0003
903 MALAISE 98 0.0003
904 DRY SKIN 26 0.0003
905 HOSPITALISATION 27 0.0003
906 GAIT DISTURBANCE 41 0.0003
907 HYPOTHYROIDISM 6 0.0003
908 ANGIOEDEMA 9 0.0003
909 VISUAL IMPAIRMENT 23 0.0003
910 WEIGHT INCREASED 44 0.0003
911 NASOPHARYNGITIS 34 0.0003
912 MOBILITY DECREASED 14 0.0003
913 CARDIOVASCULAR DISORDER 6 0.0003
914 BLOOD POTASSIUM DECREASED 6 0.0003
915 PRURITUS 64 0.0003
916 NEUTROPHIL COUNT DECREASED 7 0.0003
917 AGITATION 16 0.0003
918 BONE DENSITY DECREASED 7 0.0003
919 BLOOD PRESSURE DECREASED 13 0.0003
920 FEELING HOT 12 0.0003
921 NECK PAIN 11 0.0003
922 UNDERDOSE 14 0.0003
923 DRUG HYPERSENSITIVITY 39 0.0003
924 NIGHTMARE 7 0.0003
925 DIZZINESS 93 0.0003
926 DEATH 154 0.0003
927 SKIN EXFOLIATION 14 0.0002
928 ACUTE MYOCARDIAL INFARCTION 6 0.0002
929 CARDIAC DISORDER 18 0.0002
930 ASTHMA 17 0.0002
931 ALOPECIA 36 0.0002
932 HEART RATE INCREASED 17 0.0002
933 DISTURBANCE IN ATTENTION 10 0.0002
934 FLUID RETENTION 9 0.0002
935 RASH PRURITIC 9 0.0002
936 ILLNESS 6 0.0002
937 PRODUCT SUBSTITUTION ISSUE 10 0.0002
938 INFLUENZA LIKE ILLNESS 15 0.0002
939 POLLAKIURIA 7 0.0002
940 SURGERY 8 0.0002
941 CORONARY ARTERY DISEASE 6 0.0002
942 FALL 54 0.0002
943 PAIN 100 0.0002
944 DRUG EFFECT INCOMPLETE 8 0.0002
945 NEOPLASM MALIGNANT 10 0.0002
946 HYPOACUSIS 6 0.0002
947 PALPITATIONS 18 0.0002
948 BURNING SENSATION 11 0.0002
949 PROSTATE CANCER 13 0.0002
950 CONTUSION 14 0.0002
951 PAIN IN EXTREMITY 45 0.0002
952 BACK PAIN 34 0.0002
953 OSTEOARTHRITIS 6 0.0002
954 AMNESIA 10 0.0002
955 ERYTHEMA 29 0.0002
956 BLOOD GLUCOSE INCREASED 28 0.0002
957 HALLUCINATION 10 0.0002
958 MYOCARDIAL INFARCTION 28 0.0002
959 LUNG NEOPLASM MALIGNANT 6 0.0002
960 IRRITABILITY 9 0.0002
961 OVERDOSE 29 0.0002
962 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 7 0.0002
963 ABNORMAL BEHAVIOUR 6 0.0002
964 CONSTIPATION 26 0.0002
965 ADVERSE EVENT 12 0.0002
966 URTICARIA 20 0.0002
967 HYPERSENSITIVITY 23 0.0002
968 CARDIAC FAILURE CONGESTIVE 12 0.0002
969 STOMATITIS 7 0.0002
970 MIGRAINE 11 0.0002
971 DYSPHONIA 7 0.0002
972 DEPRESSION 30 0.0002
973 MEDICATION ERROR 7 0.0002
974 MEMORY IMPAIRMENT 16 0.0002
975 NO ADVERSE EVENT 16 0.0002
976 CEREBROVASCULAR ACCIDENT 21 0.0002
977 DRY MOUTH 9 0.0002
978 MUSCLE SPASMS 21 0.0002
979 ANXIETY 33 0.0002
980 UNEVALUABLE EVENT 9 0.0001
981 ACNE 9 0.0001
982 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 11 0.0001
983 FLATULENCE 6 0.0001
984 HYPERHIDROSIS 14 0.0001
985 INTENTIONAL OVERDOSE 6 0.0001
986 HYPOAESTHESIA 15 0.0001
987 FEELING ABNORMAL 25 0.0001
988 ACCIDENTAL EXPOSURE TO PRODUCT 6 0.0001
989 PARAESTHESIA 15 0.0001
990 EPISTAXIS 7 0.0001
991 EMOTIONAL DISTRESS 12 0.0001
992 MALIGNANT NEOPLASM PROGRESSION 7 0.0001
993 BALANCE DISORDER 6 0.0001
994 BREAST CANCER 7 0.0001
995 INCORRECT DOSE ADMINISTERED 10 0.0001
996 PRODUCT QUALITY ISSUE 8 0.0001