Asparagine-specific Enzyme [EPC]

Asparagine-specific Enzyme [EPC] was reported 7947 times

Drugs of the Asparagine-specific Enzyme [EPC] class are most commonly taken among patients reporting these side effects:

# Drug class Count Frequency
0 LYMPHOID TISSUE HYPOPLASIA 31 0.9118
1 ANTITHROMBIN III 13 0.8667
2 HUMAN BOCAVIRUS INFECTION 86 0.7107
3 THYMUS HYPOPLASIA 37 0.6727
4 GALLBLADDER FIBROSIS 4 0.5000
5 PERINEAL NECROSIS 12 0.4800
6 HYPOFIBRINOGENAEMIA 248 0.3899
7 MYCOBACTERIUM CHELONAE INFECTION 151 0.3275
8 CYSTITIS BACTERIAL 58 0.3085
9 LEWIS-SUMNER SYNDROME 8 0.2581
10 NOROVIRUS TEST POSITIVE 57 0.2446
11 DISSEMINATED ASPERGILLOSIS 19 0.2405
12 PERIORBITAL INFECTION 11 0.2340
13 SECONDARY IMMUNODEFICIENCY 152 0.2317
14 ABSCESS BACTERIAL 62 0.2313
15 FEBRILE BONE MARROW APLASIA 528 0.1881
16 BACILLUS BACTERAEMIA 10 0.1639
17 BACILLUS TEST POSITIVE 12 0.1600
18 ANTITHROMBIN III DECREASED 33 0.1557
19 CORONA VIRUS INFECTION 67 0.1516
20 ANTITHROMBIN III DEFICIENCY 10 0.1515
21 MULTIPLE LENTIGINES SYNDROME 5 0.1515
22 RHINOCEREBRAL MUCORMYCOSIS 8 0.1404
23 PERINEAL INFECTION 13 0.1300
24 OVERGROWTH FUNGAL 7 0.1273
25 ANORECTAL CELLULITIS 6 0.1224
26 PARAINFLUENZAE VIRUS INFECTION 113 0.1209
27 PSEUDOMONAL SEPSIS 142 0.1174
28 SPLENIC INFECTION FUNGAL 4 0.1111
29 STOMATOCOCCAL INFECTION 8 0.0964
30 LIMBAL STEM CELL DEFICIENCY 4 0.0930
31 HUMAN RHINOVIRUS TEST POSITIVE 14 0.0909
32 ABSCESS FUNGAL 9 0.0891
33 CITROBACTER TEST POSITIVE 4 0.0889
34 ENTEROVIRUS TEST POSITIVE 8 0.0870
35 HUMAN METAPNEUMOVIRUS TEST POSITIVE 6 0.0857
36 RENAL REPLACEMENT THERAPY 8 0.0825
37 PYOMYOSITIS 16 0.0796
38 ENTEROBACTER INFECTION 91 0.0793
39 MUCOCUTANEOUS ULCERATION 10 0.0781
40 BONE MARROW LEUKAEMIC CELL INFILTRATION 3 0.0769
41 CEREBRAL MASS EFFECT 3 0.0750
42 DIFFUSE ALVEOLAR DAMAGE 64 0.0736
43 GALLBLADDER OEDEMA 16 0.0699
44 RHINOVIRUS INFECTION 114 0.0691
45 ADENOVIRUS TEST POSITIVE 4 0.0690
46 SUPERIOR SAGITTAL SINUS THROMBOSIS 46 0.0667
47 LEUKAEMIC INFILTRATION 6 0.0659
48 HYPERTRIGLYCERIDAEMIA 261 0.0651
49 BLOOD FIBRINOGEN DECREASED 44 0.0648
50 CYTOMEGALOVIRUS CHORIORETINITIS 81 0.0639
51 HUMAN HERPESVIRUS 6 INFECTION 92 0.0638
52 CHOLANGITIS INFECTIVE 8 0.0625
53 MUCOSAL INFECTION 11 0.0595
54 PSEUDOMONAS TEST POSITIVE 33 0.0570
55 PNEUMATOSIS INTESTINALIS 94 0.0542
56 VIRAEMIA 42 0.0532
57 ENCOPRESIS 8 0.0516
58 PROTHROMBIN LEVEL ABNORMAL 7 0.0493
59 CANDIDA TEST POSITIVE 15 0.0487
60 CHEMOTHERAPEUTIC DRUG LEVEL INCREASED 5 0.0485
61 CRYPTOCOCCAL FUNGAEMIA 3 0.0423
62 UREAPLASMA INFECTION 7 0.0422
63 ESCHERICHIA PYELONEPHRITIS 6 0.0417
64 HERPES SIMPLEX TEST POSITIVE 4 0.0417
65 ENTEROBACTER TEST POSITIVE 8 0.0408
66 CAECITIS 17 0.0378
67 KERATITIS BACTERIAL 4 0.0377
68 INFECTIVE MYOSITIS 4 0.0374
69 PULMONARY MUCORMYCOSIS 5 0.0368
70 CYTOMEGALOVIRUS VIRAEMIA 86 0.0367
71 LENTIGO 11 0.0367
72 BLOOD CULTURE POSITIVE 97 0.0365
73 CEREBRAL VENOUS SINUS THROMBOSIS 9 0.0360
74 CLOSTRIDIUM TEST POSITIVE 42 0.0359
75 ESCHERICHIA TEST POSITIVE 31 0.0359
76 AEROMONAS INFECTION 4 0.0357
77 GASTROENTERITIS NOROVIRUS 38 0.0353
78 PNEUMONIA NECROTISING 12 0.0353
79 MUCORMYCOSIS 55 0.0352
80 HERPES ZOSTER MENINGOENCEPHALITIS 7 0.0341
81 ZYGOMYCOSIS 16 0.0340
82 HYPERBILIRUBINAEMIA 242 0.0340
83 ENTEROCOCCUS TEST POSITIVE 16 0.0335
84 OESOPHAGEAL CANDIDIASIS 90 0.0333
85 BACILLUS INFECTION 13 0.0326
86 POTENTIATING DRUG INTERACTION 73 0.0318
87 FUSARIUM INFECTION 13 0.0316
88 CLOSTRIDIUM BACTERAEMIA 4 0.0315
89 TRANSVERSE SINUS THROMBOSIS 14 0.0312
90 PSEUDOMONAL BACTERAEMIA 14 0.0302
91 BLOOD LACTIC ACID DECREASED 3 0.0300
92 ASPERGILLUS INFECTION 105 0.0296
93 CEREBRAL VENOUS THROMBOSIS 41 0.0296
94 TRICHOSPORON INFECTION 8 0.0295
95 ENTEROBACTER BACTERAEMIA 5 0.0287
96 INTUSSUSCEPTION 17 0.0284
97 PANCREATITIS NECROTISING 35 0.0277
98 PROTEUS TEST POSITIVE 4 0.0276
99 BRONCHOPULMONARY ASPERGILLOSIS 133 0.0272
100 CAVERNOUS SINUS THROMBOSIS 5 0.0272
101 BONE MARROW INFILTRATION 6 0.0267
102 CLOSTRIDIAL SEPSIS 3 0.0261
103 NEUTROPENIC COLITIS 29 0.0258
104 VULVITIS 6 0.0250
105 ANORECTAL INFECTION 4 0.0247
106 VENOOCCLUSIVE LIVER DISEASE 80 0.0247
107 ESCHERICHIA BACTERAEMIA 33 0.0243
108 CLOSTRIDIUM DIFFICILE COLITIS 182 0.0243
109 KLEBSIELLA TEST POSITIVE 11 0.0243
110 OTITIS MEDIA ACUTE 13 0.0239
111 SINUSITIS FUNGAL 11 0.0239
112 ACUTE LYMPHOCYTIC LEUKAEMIA RECURRENT 35 0.0239
113 ENTEROVIRUS INFECTION 10 0.0239
114 INTRACARDIAC THROMBUS 64 0.0237
115 INTRACRANIAL VENOUS SINUS THROMBOSIS 25 0.0233
116 VENOUS THROMBOSIS 71 0.0233
117 B PRECURSOR TYPE ACUTE LEUKAEMIA 4 0.0229
118 HEPATOBILIARY DISEASE 9 0.0218
119 ENTERITIS 86 0.0217
120 ANAL ULCER 11 0.0217
121 GASTROINTESTINAL WALL THICKENING 17 0.0212
122 BACTERIAL INFECTION 253 0.0211
123 VASCULAR ACCESS COMPLICATION 11 0.0210
124 RESPIRATORY SYNCYTIAL VIRUS TEST POSITIVE 8 0.0207
125 METASTASES TO PANCREAS 6 0.0206
126 FEBRILE NEUTROPENIA 863 0.0205
127 RESPIRATORY TRACT INFECTION FUNGAL 9 0.0205
128 STREPTOCOCCUS TEST POSITIVE 17 0.0204
129 GASTROENTERITIS ROTAVIRUS 4 0.0202
130 CORONAVIRUS TEST POSITIVE 11 0.0201
131 AXILLARY VEIN THROMBOSIS 6 0.0201
132 BACTERIAL TRANSLOCATION 3 0.0200
133 LOWER RESPIRATORY TRACT INFECTION FUNGAL 7 0.0200
134 ESCHERICHIA SEPSIS 42 0.0198
135 FUNGAEMIA 20 0.0197
136 PLATELET TRANSFUSION 14 0.0196
137 ASPERGILLUS TEST POSITIVE 4 0.0189
138 JUGULAR VEIN THROMBOSIS 24 0.0189
139 PERIRECTAL ABSCESS 17 0.0187
140 BRAIN MIDLINE SHIFT 10 0.0186
141 FUNGAL TEST POSITIVE 5 0.0185
142 PNEUMATOSIS 6 0.0185
143 ENTEROCOLITIS INFECTIOUS 13 0.0183
144 PANCREATITIS HAEMORRHAGIC 6 0.0181
145 APLASIA 31 0.0180
146 STEATOHEPATITIS 6 0.0180
147 PERIPHERAL MOTOR NEUROPATHY 18 0.0179
148 STAPHYLOCOCCUS TEST POSITIVE 29 0.0177
149 DRUG CLEARANCE DECREASED 14 0.0177
150 CELLULITIS ORBITAL 7 0.0177
151 POST LUMBAR PUNCTURE SYNDROME 12 0.0177
152 CANDIDA SEPSIS 12 0.0176
153 SYSTEMIC CANDIDA 25 0.0175
154 PANCREATIC PSEUDOCYST 11 0.0174
155 BLOOD IMMUNOGLOBULIN A DECREASED 6 0.0174
156 CEREBRAL THROMBOSIS 37 0.0174
157 GASTROENTERITIS ESCHERICHIA COLI 4 0.0169
158 CYSTITIS VIRAL 3 0.0169
159 LIVER TENDERNESS 4 0.0163
160 ECTHYMA 4 0.0160
161 VENOOCCLUSIVE DISEASE 27 0.0156
162 HYPOALBUMINAEMIA 79 0.0155
163 SARS-COV-2 TEST NEGATIVE 5 0.0153
164 HEPATOCELLULAR INJURY 176 0.0144
165 PANCREATIC NECROSIS 5 0.0141
166 CANDIDA PNEUMONIA 3 0.0140
167 HYPERLIPASAEMIA 5 0.0139
168 POSTURING 6 0.0136
169 NEUTRALISING ANTIBODIES POSITIVE 4 0.0135
170 CAMPYLOBACTER INFECTION 6 0.0133
171 METAPNEUMOVIRUS INFECTION 5 0.0133
172 CENTRAL VENOUS CATHETER REMOVAL 4 0.0132
173 BLOOD LACTIC ACID INCREASED 44 0.0130
174 RESPIRATORY TRACT HAEMORRHAGE 6 0.0129
175 SYSTEMIC MYCOSIS 9 0.0128
176 LEUKOENCEPHALOPATHY 36 0.0127
177 LIPASE INCREASED 73 0.0127
178 HYPERAMMONAEMIA 43 0.0127
179 PNEUMONIA FUNGAL 23 0.0123
180 FUNGAL SEPSIS 8 0.0123
181 POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME 74 0.0122
182 ALPHA HAEMOLYTIC STREPTOCOCCAL INFECTION 7 0.0122
183 OESOPHAGITIS ULCERATIVE 6 0.0120
184 COATING IN MOUTH 4 0.0120
185 HISTIOCYTOSIS HAEMATOPHAGIC 36 0.0119
186 RECTAL FISSURE 6 0.0118
187 ABDOMINAL COMPARTMENT SYNDROME 5 0.0116
188 OEDEMATOUS PANCREATITIS 4 0.0113
189 HEPATIC CYTOLYSIS 10 0.0113
190 SEPTIC EMBOLUS 7 0.0111
191 MUCOSAL INFLAMMATION 197 0.0108
192 CENTRAL NERVOUS SYSTEM INFECTION 8 0.0107
193 VASOGENIC CEREBRAL OEDEMA 4 0.0107
194 PRODUCT CONTAMINATION MICROBIAL 8 0.0106
195 CORNEAL EPITHELIUM DEFECT 4 0.0105
196 CATARRH 5 0.0103
197 IRREGULAR BREATHING 4 0.0102
198 STAPHYLOCOCCAL SEPSIS 39 0.0101
199 BACTERAEMIA 75 0.0100
200 KLEBSIELLA BACTERAEMIA 5 0.0100
201 PORPHYRIA NON-ACUTE 4 0.0099
202 GASTROINTESTINAL NECROSIS 22 0.0099
203 HERPES SIMPLEX 45 0.0098
204 SOFT TISSUE INFECTION 12 0.0098
205 INTERVERTEBRAL DISCITIS 12 0.0097
206 QUADRIPARESIS 10 0.0093
207 PULSE ABSENT 35 0.0093
208 PUPIL FIXED 13 0.0091
209 BRAIN HERNIATION 20 0.0090
210 OESOPHAGEAL STENOSIS 18 0.0090
211 VASCULITIS CEREBRAL 4 0.0088
212 OPTIC NERVE DISORDER 11 0.0088
213 PACKED RED BLOOD CELL TRANSFUSION 11 0.0087
214 URETERIC OBSTRUCTION 9 0.0087
215 THALAMIC INFARCTION 4 0.0085
216 COAGULOPATHY 109 0.0085
217 SUBCLAVIAN VEIN THROMBOSIS 8 0.0085
218 CHOLESTASIS 111 0.0084
219 GRUNTING 4 0.0084
220 BILIRUBIN CONJUGATED INCREASED 15 0.0084
221 ANAL INFLAMMATION 3 0.0084
222 ENTEROCOLITIS 28 0.0083
223 HEPATOMEGALY 64 0.0082
224 HEART SOUNDS ABNORMAL 5 0.0082
225 VIRAL INFECTION 180 0.0081
226 BACTERIAL SEPSIS 19 0.0081
227 SEPTIC SHOCK 232 0.0080
228 SUBCUTANEOUS EMPHYSEMA 5 0.0079
229 BRAIN DEATH 18 0.0079
230 TRANSFUSION REACTION 5 0.0078
231 ISCHAEMIC CEREBRAL INFARCTION 7 0.0078
232 SOFT TISSUE NECROSIS 4 0.0078
233 KLEBSIELLA SEPSIS 6 0.0078
234 TACHYPNOEA 69 0.0077
235 BLOOD BILIRUBIN INCREASED 161 0.0077
236 CAPILLARY LEAK SYNDROME 10 0.0077
237 DEVICE RELATED THROMBOSIS 4 0.0076
238 BLOOD FIBRINOGEN INCREASED 5 0.0076
239 CONTINUOUS HAEMODIAFILTRATION 7 0.0075
240 CYTOGENETIC ANALYSIS ABNORMAL 5 0.0075
241 PULMONARY HAEMORRHAGE 46 0.0075
242 BLOOD IMMUNOGLOBULIN G DECREASED 8 0.0075
243 PANCREATITIS ACUTE 117 0.0075
244 TONIC CLONIC MOVEMENTS 7 0.0075
245 PHARYNGEAL INFLAMMATION 6 0.0074
246 BACTERIAL TEST POSITIVE 12 0.0074
247 INTRACRANIAL HYPOTENSION 4 0.0074
248 STENOTROPHOMONAS INFECTION 6 0.0073
249 BLOOD GASES ABNORMAL 3 0.0073
250 NEUROLOGICAL DECOMPENSATION 11 0.0072
251 STAPHYLOCOCCAL BACTERAEMIA 20 0.0072
252 HEPATIC STEATOSIS 95 0.0072
253 PSEUDOMONAS INFECTION 39 0.0072
254 HYPERPHOSPHATAEMIA 9 0.0071
255 CEREBROSPINAL FLUID LEAKAGE 9 0.0071
256 EMBOLISM VENOUS 15 0.0071
257 PNEUMONIA LEGIONELLA 8 0.0070
258 EPSTEIN-BARR VIRAEMIA 4 0.0070
259 ESCHERICHIA INFECTION 37 0.0070
260 COMPUTERISED TOMOGRAM THORAX ABNORMAL 4 0.0069
261 CATHETER SITE HAEMORRHAGE 12 0.0069
262 KLEBSIELLA INFECTION 22 0.0069
263 RED MAN SYNDROME 6 0.0068
264 LEUKAEMIA RECURRENT 9 0.0068
265 DEVICE RELATED SEPSIS 9 0.0067
266 VARICELLA 12 0.0067
267 STEROID DIABETES 4 0.0066
268 PNEUMOMEDIASTINUM 7 0.0066
269 COLITIS 152 0.0066
270 BREAKTHROUGH PAIN 13 0.0066
271 ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED 27 0.0066
272 PROCALCITONIN INCREASED 4 0.0063
273 CHOLANGITIS ACUTE 3 0.0063
274 PULSELESS ELECTRICAL ACTIVITY 18 0.0063
275 ORAL HERPES 76 0.0063
276 PNEUMOPERITONEUM 8 0.0063
277 DUODENAL PERFORATION 4 0.0063
278 PANCREATITIS 248 0.0062
279 ELECTROCARDIOGRAM REPOLARISATION ABNORMALITY 4 0.0062
280 URTICARIA GENERALISED 4 0.0062
281 STREPTOCOCCAL BACTERAEMIA 4 0.0061
282 CEREBRAL ISCHAEMIA 26 0.0061
283 MULTIPLE ORGAN DYSFUNCTION SYNDROME 91 0.0061
284 GASTROINTESTINAL BACTERIAL INFECTION 4 0.0060
285 HEPATOTOXICITY 86 0.0060
286 PNEUMONIA KLEBSIELLA 7 0.0060
287 HEPATORENAL SYNDROME 8 0.0059
288 RESPIRATORY DISTRESS 123 0.0059
289 FUNGAL INFECTION 135 0.0059
290 BONE MARROW FAILURE 105 0.0058
291 PERTUSSIS 4 0.0058
292 CANDIDA INFECTION 59 0.0058
293 DISSEMINATED INTRAVASCULAR COAGULATION 64 0.0058
294 MENINGITIS BACTERIAL 6 0.0057
295 ACIDOSIS 33 0.0057
296 MYELOSUPPRESSION 24 0.0057
297 ENCEPHALITIS 26 0.0057
298 AMYLASE INCREASED 14 0.0057
299 ASCITES 120 0.0056
300 DEVICE RELATED INFECTION 68 0.0056
301 HEPATOSPLENOMEGALY 11 0.0055
302 PANCREATIC CYST 7 0.0055
303 AORTIC DILATATION 4 0.0055
304 CORONAVIRUS INFECTION 18 0.0055
305 NEUROTOXICITY 57 0.0054
306 LUNG OPACITY 4 0.0054
307 CULTURE POSITIVE 4 0.0054
308 SUBILEUS 9 0.0054
309 HYPERLIPIDAEMIA 51 0.0053
310 INTESTINAL DILATATION 5 0.0053
311 ANAPHYLACTIC REACTION 185 0.0053
312 EPSTEIN-BARR VIRUS ASSOCIATED LYMPHOPROLIFERATIVE DISORDER 6 0.0053
313 NEPHRECTOMY 5 0.0052
314 GAMMA-GLUTAMYLTRANSFERASE INCREASED 91 0.0051
315 QUADRIPLEGIA 8 0.0051
316 IRON OVERLOAD 4 0.0051
317 FIBRIN D DIMER INCREASED 12 0.0050
318 BLOOD BILIRUBIN ABNORMAL 4 0.0050
319 DISTRIBUTIVE SHOCK 3 0.0050
320 ENTEROCOCCAL INFECTION 16 0.0050
321 INTRA-ABDOMINAL FLUID COLLECTION 5 0.0050
322 CEREBRAL VASOCONSTRICTION 3 0.0050
323 HYPERGLYCAEMIA 133 0.0049
324 ILEUS 43 0.0049
325 BRAIN ABSCESS 8 0.0049
326 EMBOLISM 31 0.0049
327 ATRIAL THROMBOSIS 8 0.0049
328 ANGIONEUROTIC OEDEMA 13 0.0049
329 NEUTROPENIA 392 0.0049
330 MITRAL VALVE DISEASE 7 0.0049
331 TUMOUR LYSIS SYNDROME 26 0.0049
332 LUNG CONSOLIDATION 10 0.0048
333 OBLITERATIVE BRONCHIOLITIS 5 0.0048
334 REVERSIBLE CEREBRAL VASOCONSTRICTION SYNDROME 4 0.0048
335 KIDNEY ENLARGEMENT 4 0.0048
336 CHOLESTATIC LIVER INJURY 5 0.0048
337 ILEUS PARALYTIC 15 0.0047
338 APNOEA 29 0.0047
339 BLOOD ALBUMIN INCREASED 3 0.0047
340 GLYCOSURIA 5 0.0047
341 ATELECTASIS 35 0.0046
342 CSF PROTEIN INCREASED 3 0.0046
343 MENINGITIS 22 0.0046
344 RESPIRATORY SYNCYTIAL VIRUS INFECTION 16 0.0046
345 VOCAL CORD PARALYSIS 6 0.0045
346 ADENOVIRUS INFECTION 8 0.0045
347 EPSTEIN-BARR VIRUS INFECTION 19 0.0045
348 HEPATIC FAILURE 103 0.0045
349 PNEUMONIA VIRAL 9 0.0045
350 LEFT VENTRICULAR DYSFUNCTION 21 0.0044
351 ACUTE LYMPHOCYTIC LEUKAEMIA 9 0.0044
352 SEPSIS 353 0.0044
353 PUPILS UNEQUAL 5 0.0044
354 PERIPHERAL SENSORY NEUROPATHY 17 0.0044
355 LIP HAEMORRHAGE 4 0.0044
356 HYPOXIA 102 0.0042
357 BLAST CELL COUNT INCREASED 3 0.0042
358 HEPATIC CONGESTION 4 0.0042
359 ESCHERICHIA URINARY TRACT INFECTION 13 0.0042
360 ALANINE AMINOTRANSFERASE INCREASED 193 0.0042
361 CHOLECYSTITIS 36 0.0041
362 UNRESPONSIVE TO STIMULI 77 0.0041
363 RESPIRATORY TRACT INFECTION VIRAL 5 0.0041
364 BRAIN HYPOXIA 3 0.0041
365 PANCYTOPENIA 155 0.0040
366 BRAIN OEDEMA 37 0.0040
367 SERUM FERRITIN INCREASED 15 0.0040
368 PULMONARY INFARCTION 8 0.0040
369 VARICELLA ZOSTER VIRUS INFECTION 5 0.0040
370 AMMONIA INCREASED 16 0.0040
371 SINUS TACHYCARDIA 42 0.0040
372 HAEMODYNAMIC INSTABILITY 19 0.0039
373 SPLENIC INFARCTION 5 0.0039
374 EFFUSION 4 0.0039
375 FACIAL PARALYSIS 21 0.0039
376 COMPUTERISED TOMOGRAM ABNORMAL 7 0.0038
377 RENAL INFARCT 4 0.0038
378 VASCULAR DEVICE INFECTION 6 0.0038
379 HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS 9 0.0038
380 NEUTROPHIL COUNT DECREASED 92 0.0037
381 CHOLECYSTITIS ACUTE 16 0.0037
382 NECROSIS 16 0.0037
383 BK VIRUS INFECTION 7 0.0037
384 TACHYCARDIA 231 0.0037
385 PROCTITIS 6 0.0037
386 PLEURITIC PAIN 8 0.0036
387 STREPTOCOCCAL INFECTION 13 0.0036
388 HYPOPHAGIA 61 0.0035
389 URINE OUTPUT DECREASED 24 0.0035
390 MENTAL STATUS CHANGES 74 0.0035
391 HYDROCEPHALUS 14 0.0035
392 HYPERNATRAEMIA 12 0.0035
393 RENAL COLIC 6 0.0035
394 BONE MARROW DISORDER 7 0.0034
395 NUCLEAR MAGNETIC RESONANCE IMAGING BRAIN ABNORMAL 5 0.0034
396 ANAL FISSURE 9 0.0034
397 ENCEPHALOPATHY 57 0.0034
398 STEM CELL TRANSPLANT 6 0.0034
399 ACUTE ABDOMEN 4 0.0034
400 DRUG-INDUCED LIVER INJURY 53 0.0033
401 CULTURE URINE POSITIVE 4 0.0033
402 HEMIPARESIS 44 0.0033
403 INTRACRANIAL PRESSURE INCREASED 13 0.0033
404 GAZE PALSY 4 0.0033
405 INTESTINAL ISCHAEMIA 13 0.0033
406 HYPOPROTEINAEMIA 4 0.0032
407 CYTOKINE RELEASE SYNDROME 15 0.0032
408 ENDOPHTHALMITIS 13 0.0032
409 PROTHROMBIN TIME PROLONGED 17 0.0032
410 BLOOD PRESSURE IMMEASURABLE 4 0.0032
411 HYPERCHOLESTEROLAEMIA 19 0.0032
412 ORAL DISORDER 17 0.0032
413 THROMBOCYTOPENIA 244 0.0032
414 SPLEEN DISORDER 4 0.0032
415 CELLULITIS 118 0.0032
416 SHOCK 50 0.0031
417 ANAL HAEMORRHAGE 6 0.0031
418 CYSTITIS 73 0.0031
419 PLEURAL EFFUSION 136 0.0030
420 ACUTE RESPIRATORY DISTRESS SYNDROME 38 0.0030
421 TRANSAMINASES INCREASED 49 0.0030
422 BICYTOPENIA 3 0.0030
423 LIP OEDEMA 9 0.0030
424 NON-CARDIAC CHEST PAIN 8 0.0029
425 LYMPHOPENIA 27 0.0029
426 CYTOPENIA 15 0.0029
427 HERPES VIRUS INFECTION 12 0.0029
428 CLOSTRIDIUM COLITIS 3 0.0029
429 PARESIS 5 0.0029
430 PROCTALGIA 13 0.0029
431 BLOOD TRIGLYCERIDES INCREASED 40 0.0029
432 OPPORTUNISTIC INFECTION 4 0.0029
433 PROTEIN TOTAL DECREASED 8 0.0029
434 GASTROINTESTINAL INJURY 6 0.0028
435 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 21 0.0028
436 MULTIPLE-DRUG RESISTANCE 4 0.0028
437 PERONEAL NERVE PALSY 12 0.0028
438 FLUID OVERLOAD 41 0.0028
439 MALNUTRITION 21 0.0028
440 BLOOD PHOSPHORUS INCREASED 5 0.0028
441 FOETAL GROWTH RESTRICTION 11 0.0028
442 LUNG INFECTION 43 0.0027
443 HYPOPHOSPHATAEMIA 13 0.0027
444 PALLOR 50 0.0027
445 SYSTEMIC INFLAMMATORY RESPONSE SYNDROME 8 0.0027
446 BRONCHIAL OBSTRUCTION 3 0.0027
447 HAEMORRHAGE INTRACRANIAL 33 0.0027
448 DIALYSIS 30 0.0027
449 PULMONARY MASS 26 0.0027
450 MULTI-ORGAN DISORDER 4 0.0026
451 HYPERCOAGULATION 4 0.0026
452 ANURIA 18 0.0026
453 DYSLIPIDAEMIA 9 0.0026
454 NEOPLASM RECURRENCE 6 0.0026
455 CHRONIC SINUSITIS 6 0.0026
456 CLOSTRIDIUM DIFFICILE INFECTION 35 0.0025
457 HEPATIC FIBROSIS 6 0.0025
458 FAECES HARD 6 0.0025
459 HYPOTENSION 357 0.0025
460 INTRAVENTRICULAR HAEMORRHAGE 5 0.0025
461 RESPIRATORY FAILURE 136 0.0025
462 CORNEAL OEDEMA 4 0.0025
463 URINARY TRACT INFECTION BACTERIAL 4 0.0025
464 MUCOUS STOOLS 6 0.0025
465 NEUTROPENIC SEPSIS 13 0.0024
466 BRAIN NATRIURETIC PEPTIDE INCREASED 5 0.0024
467 CENTRAL VENOUS CATHETERISATION 5 0.0024
468 AREFLEXIA 5 0.0024
469 OCULAR ICTERUS 8 0.0024
470 ORTHOPNOEA 6 0.0024
471 LARGE INTESTINE PERFORATION 12 0.0024
472 ASPARTATE AMINOTRANSFERASE INCREASED 94 0.0023
473 HEPATITIS CHOLESTATIC 10 0.0023
474 HYPOKALAEMIA 74 0.0023
475 PARAPLEGIA 5 0.0023
476 PERICARDIAL EFFUSION 36 0.0023
477 NEUTROPHIL COUNT ABNORMAL 4 0.0022
478 TYPE IV HYPERSENSITIVITY REACTION 4 0.0022
479 PYREXIA 537 0.0022
480 GRAFT VERSUS HOST DISEASE 12 0.0022
481 BLOOD ALBUMIN DECREASED 13 0.0022
482 CYSTITIS HAEMORRHAGIC 6 0.0022
483 GENERALISED TONIC-CLONIC SEIZURE 22 0.0021
484 HAEMODIALYSIS 17 0.0021
485 HYPERTRANSAMINASAEMIA 5 0.0021
486 POOR PERIPHERAL CIRCULATION 7 0.0021
487 FACIAL PARESIS 6 0.0021
488 MOUTH HAEMORRHAGE 11 0.0021
489 GENERALISED OEDEMA 18 0.0021
490 ANAPHYLACTIC SHOCK 36 0.0021
491 OLIGURIA 10 0.0021
492 SEIZURE 147 0.0021
493 BODY TEMPERATURE INCREASED 32 0.0021
494 LARGE INTESTINAL ULCER 4 0.0021
495 NECROTISING FASCIITIS 5 0.0021
496 CEREBRAL HAEMORRHAGE 56 0.0021
497 LOW BIRTH WEIGHT BABY 11 0.0021
498 CARDIO-RESPIRATORY ARREST 69 0.0021
499 ABDOMINAL PAIN 338 0.0021
500 OXYGEN SATURATION DECREASED 70 0.0021
501 HAEMATOTOXICITY 11 0.0021
502 HYPOVOLAEMIA 9 0.0020
503 STAPHYLOCOCCAL INFECTION 52 0.0020
504 SUBDURAL HAEMATOMA 23 0.0020
505 HYPONATRAEMIA 84 0.0020
506 METABOLIC ACIDOSIS 43 0.0020
507 TYPE 1 DIABETES MELLITUS 8 0.0020
508 HYPOTHERMIA 15 0.0020
509 CHEST X-RAY ABNORMAL 5 0.0020
510 CATHETER SITE ERYTHEMA 3 0.0020
511 STOMATITIS 79 0.0020
512 PARTIAL SEIZURES 7 0.0020
513 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 14 0.0020
514 INFUSION RELATED REACTION 74 0.0020
515 PETECHIAE 15 0.0020
516 TOXIC ENCEPHALOPATHY 6 0.0020
517 CARDIAC DYSFUNCTION 3 0.0020
518 CLOSTRIDIAL INFECTION 6 0.0020
519 CEREBRAL HAEMATOMA 5 0.0019
520 FAILURE TO THRIVE 8 0.0019
521 ELECTROENCEPHALOGRAM ABNORMAL 5 0.0019
522 CEREBRAL ATROPHY 6 0.0019
523 GASTROINTESTINAL TOXICITY 5 0.0019
524 WOUND DEHISCENCE 5 0.0019
525 HYPOCALCAEMIA 25 0.0019
526 BLOOD BICARBONATE DECREASED 3 0.0019
527 METABOLIC ENCEPHALOPATHY 4 0.0019
528 ACUTE RESPIRATORY FAILURE 23 0.0019
529 LEUKOPENIA 66 0.0019
530 LARYNGOSPASM 4 0.0019
531 LACTIC ACIDOSIS 38 0.0019
532 FLUID INTAKE REDUCED 6 0.0019
533 PERIORBITAL OEDEMA 7 0.0019
534 CATHETER SITE INFECTION 5 0.0018
535 LUNG INFILTRATION 14 0.0018
536 FUNGAL SKIN INFECTION 5 0.0018
537 HYPERSENSITIVITY 238 0.0018
538 PORTAL HYPERTENSION 4 0.0018
539 APPENDICITIS 11 0.0018
540 DIASTOLIC DYSFUNCTION 4 0.0018
541 PLATELET COUNT DECREASED 131 0.0018
542 BRADYCARDIA 71 0.0018
543 EYE MOVEMENT DISORDER 9 0.0018
544 HYPOVOLAEMIC SHOCK 6 0.0018
545 ODYNOPHAGIA 7 0.0017
546 INTESTINAL PERFORATION 14 0.0017
547 LEUKAEMIA 11 0.0017
548 PORTAL VEIN THROMBOSIS 4 0.0017
549 INFUSION SITE EXTRAVASATION 7 0.0017
550 HEPATIC LESION 5 0.0017
551 HEMIPLEGIA 11 0.0017
552 HEPATIC ENCEPHALOPATHY 12 0.0017
553 APPENDICITIS PERFORATED 3 0.0017
554 REGURGITATION 4 0.0017
555 HEPATITIS ACUTE 8 0.0017
556 LIVER INJURY 20 0.0017
557 THROMBOCYTOSIS 4 0.0017
558 ENDOCARDITIS 6 0.0017
559 LIVER FUNCTION TEST INCREASED 20 0.0017
560 POSTURE ABNORMAL 4 0.0017
561 POLYDIPSIA 5 0.0017
562 SHOCK HAEMORRHAGIC 9 0.0016
563 THROMBOPHLEBITIS SUPERFICIAL 5 0.0016
564 PATHOGEN RESISTANCE 9 0.0016
565 ABDOMINAL ABSCESS 5 0.0016
566 SUBARACHNOID HAEMORRHAGE 12 0.0016
567 METABOLIC DISORDER 7 0.0016
568 ACUTE KIDNEY INJURY 157 0.0016
569 HAEMATEMESIS 31 0.0016
570 ANAPHYLACTOID REACTION 5 0.0016
571 ABDOMINAL TENDERNESS 6 0.0016
572 CARDIOPULMONARY FAILURE 5 0.0016
573 LOOSE TOOTH 4 0.0016
574 PHOTOPHOBIA 19 0.0015
575 COMPARTMENT SYNDROME 3 0.0015
576 RESPIRATORY ACIDOSIS 4 0.0015
577 MOTOR DYSFUNCTION 11 0.0015
578 CEREBRAL INFARCTION 28 0.0015
579 HALLUCINATIONS, MIXED 4 0.0015
580 PYELONEPHRITIS 9 0.0015
581 VENTRICULAR ARRHYTHMIA 4 0.0015
582 METASTASIS 7 0.0015
583 JAUNDICE CHOLESTATIC 4 0.0015
584 ACUTE MYELOID LEUKAEMIA 16 0.0015
585 VENTRICULAR TACHYCARDIA 18 0.0015
586 PNEUMOTHORAX 16 0.0015
587 LIP SWELLING 35 0.0015
588 ANAL INCONTINENCE 7 0.0015
589 CARDIAC ARREST 92 0.0015
590 TRANSFUSION 11 0.0014
591 SCREAMING 7 0.0014
592 NEURALGIA 23 0.0014
593 GANGRENE 7 0.0014
594 CYANOSIS 17 0.0014
595 BRAIN INJURY 10 0.0014
596 SKIN ABRASION 4 0.0014
597 BLOOD CREATININE DECREASED 3 0.0014
598 DYSARTHRIA 40 0.0014
599 PULMONARY ALVEOLAR HAEMORRHAGE 5 0.0014
600 ADRENAL INSUFFICIENCY 9 0.0014
601 BLOOD CHLORIDE DECREASED 3 0.0014
602 SKIN INFECTION 10 0.0014
603 SMALL INTESTINAL OBSTRUCTION 12 0.0014
604 POLYURIA 8 0.0014
605 AGRANULOCYTOSIS 16 0.0014
606 OSTEONECROSIS 37 0.0014
607 DIARRHOEA HAEMORRHAGIC 9 0.0014
608 GASTROINTESTINAL SOUNDS ABNORMAL 4 0.0014
609 BLINDNESS TRANSIENT 7 0.0013
610 THROMBOSIS IN DEVICE 4 0.0013
611 ISCHAEMIC STROKE 18 0.0013
612 VOMITING 427 0.0013
613 BLOOD CREATINE INCREASED 4 0.0013
614 ORAL PAIN 21 0.0013
615 ECCHYMOSIS 7 0.0013
616 SKIN TOXICITY 4 0.0013
617 HYPERKALAEMIA 32 0.0013
618 BLOOD SODIUM DECREASED 17 0.0013
619 ORAL CANDIDIASIS 11 0.0013
620 GUILLAIN-BARRE SYNDROME 4 0.0013
621 JAUNDICE 27 0.0012
622 CANDIDIASIS 5 0.0012
623 SUPRAVENTRICULAR TACHYCARDIA 9 0.0012
624 INFARCTION 7 0.0012
625 RESPIRATION ABNORMAL 5 0.0012
626 BLOOD PRESSURE DECREASED 58 0.0012
627 HAEMOLYSIS 7 0.0012
628 REFUSAL OF TREATMENT BY PATIENT 6 0.0012
629 MYOSITIS 7 0.0012
630 GASTROINTESTINAL INFLAMMATION 6 0.0012
631 IMMUNOSUPPRESSION 6 0.0012
632 NEUROPATHY PERIPHERAL 71 0.0012
633 ACUTE GRAFT VERSUS HOST DISEASE 4 0.0012
634 BLOOD UREA INCREASED 16 0.0012
635 ABDOMINAL ADHESIONS 3 0.0012
636 MULTI-ORGAN FAILURE 20 0.0012
637 ANAEMIA 158 0.0011
638 DEHYDRATION 112 0.0011
639 EJECTION FRACTION DECREASED 12 0.0011
640 DRUG SPECIFIC ANTIBODY PRESENT 4 0.0011
641 APHASIA 25 0.0011
642 LETHARGY 48 0.0011
643 PULMONARY OEDEMA 36 0.0011
644 BLOOD ALKALINE PHOSPHATASE INCREASED 22 0.0011
645 ISCHAEMIA 4 0.0011
646 THROAT TIGHTNESS 21 0.0011
647 BLOOD CALCIUM DECREASED 9 0.0011
648 PRODUCT USE IN UNAPPROVED INDICATION 129 0.0011
649 RESPIRATORY TRACT INFECTION 18 0.0011
650 INTERNATIONAL NORMALISED RATIO INCREASED 28 0.0011
651 COVID-19 PNEUMONIA 4 0.0011
652 DROOLING 5 0.0011
653 HYPOGLYCAEMIA 39 0.0011
654 DEPRESSED LEVEL OF CONSCIOUSNESS 30 0.0011
655 CAROTID ARTERY STENOSIS 3 0.0011
656 FLANK PAIN 7 0.0010
657 BLOOD URIC ACID INCREASED 4 0.0010
658 SWELLING FACE 49 0.0010
659 SKIN LESION 19 0.0010
660 HYPERCALCAEMIA 9 0.0010
661 ELECTROLYTE IMBALANCE 8 0.0010
662 HEPATIC FUNCTION ABNORMAL 25 0.0010
663 PNEUMOCYSTIS JIROVECII PNEUMONIA 6 0.0010
664 CHOLANGITIS 4 0.0010
665 NEUROLOGICAL SYMPTOM 4 0.0010
666 NEPHROPATHY TOXIC 7 0.0010
667 SKIN NECROSIS 4 0.0010
668 DRUG HYPERSENSITIVITY 145 0.0010
669 ALTERED STATE OF CONSCIOUSNESS 14 0.0010
670 BLOOD PRESSURE SYSTOLIC DECREASED 3 0.0010
671 VIRAL UPPER RESPIRATORY TRACT INFECTION 4 0.0010
672 GRAND MAL CONVULSION 9 0.0010
673 PULMONARY EMBOLISM 73 0.0010
674 PERICARDITIS 7 0.0010
675 WHITE BLOOD CELL COUNT DECREASED 70 0.0010
676 TOXIC SKIN ERUPTION 7 0.0010
677 CYTOMEGALOVIRUS INFECTION 11 0.0010
678 MYDRIASIS 9 0.0010
679 INCOHERENT 5 0.0010
680 CHILLS 79 0.0010
681 FACE OEDEMA 12 0.0009
682 VENTRICULAR FIBRILLATION 8 0.0009
683 HEPATITIS 17 0.0009
684 PNEUMONIA 203 0.0009
685 DIABETIC KETOACIDOSIS 16 0.0009
686 URTICARIA 103 0.0009
687 DEEP VEIN THROMBOSIS 49 0.0009
688 HAEMOGLOBIN DECREASED 68 0.0009
689 ACUTE CORONARY SYNDROME 6 0.0009
690 INFECTION 83 0.0009
691 AUTOIMMUNE DISORDER 4 0.0009
692 ACUTE HEPATIC FAILURE 8 0.0009
693 HEPATIC CIRRHOSIS 11 0.0009
694 OESOPHAGITIS 7 0.0009
695 ANAL FISTULA 3 0.0009
696 GENERAL PHYSICAL HEALTH DETERIORATION 61 0.0009
697 MOUTH ULCERATION 12 0.0008
698 UPPER RESPIRATORY TRACT INFECTION 27 0.0008
699 RESPIRATORY DISORDER 18 0.0008
700 PNEUMONITIS 14 0.0008
701 EPISTAXIS 46 0.0008
702 ANGIOEDEMA 26 0.0008
703 CHOLELITHIASIS 20 0.0008
704 VITREOUS FLOATERS 5 0.0008
705 ABDOMINAL DISTENSION 58 0.0008
706 ASPIRATION 6 0.0008
707 BUNDLE BRANCH BLOCK RIGHT 3 0.0008
708 NEUTROPHIL COUNT INCREASED 6 0.0008
709 SINUSITIS 55 0.0008
710 MAJOR DEPRESSION 4 0.0008
711 HAEMATURIA 21 0.0008
712 RETINAL DETACHMENT 5 0.0008
713 GASTRITIS 15 0.0008
714 VASCULITIS 6 0.0008
715 HEART RATE INCREASED 53 0.0008
716 PHARYNGITIS 7 0.0008
717 COUGH 138 0.0008
718 PARALYSIS 8 0.0008
719 GASTRIC HAEMORRHAGE 7 0.0008
720 HYDRONEPHROSIS 4 0.0008
721 DECREASED APPETITE 114 0.0007
722 BRUXISM 3 0.0007
723 HERPES ZOSTER 30 0.0007
724 BLOOD CREATININE INCREASED 36 0.0007
725 OCULAR DISCOMFORT 4 0.0007
726 BRONCHOSPASM 8 0.0007
727 NEOPLASM PROGRESSION 16 0.0007
728 RHINITIS 4 0.0007
729 THERAPY NON-RESPONDER 16 0.0007
730 SALIVARY HYPERSECRETION 5 0.0007
731 EYELID PTOSIS 5 0.0007
732 TOXICITY TO VARIOUS AGENTS 80 0.0007
733 OEDEMA 27 0.0007
734 HEPATIC ENZYME INCREASED 31 0.0007
735 CENTRAL NERVOUS SYSTEM LESION 8 0.0007
736 RHINORRHOEA 29 0.0007
737 THROMBOSIS 41 0.0007
738 LIVER DISORDER 21 0.0007
739 GAIT INABILITY 11 0.0007
740 HAEMATOMA 14 0.0007
741 ACUTE PULMONARY OEDEMA 3 0.0007
742 DIABETES MELLITUS 40 0.0007
743 ELECTROCARDIOGRAM ABNORMAL 4 0.0007
744 AGITATION 39 0.0007
745 EAR PAIN 9 0.0007
746 PHARYNGEAL OEDEMA 10 0.0007
747 FACIAL PAIN 4 0.0007
748 HYPERTENSION 97 0.0007
749 MELAENA 11 0.0007
750 HYPOKINESIA 7 0.0007
751 HAEMORRHAGIC STROKE 4 0.0007
752 MYELODYSPLASTIC SYNDROME 7 0.0007
753 ABSCESS 7 0.0006
754 MUSCULAR WEAKNESS 53 0.0006
755 OROPHARYNGEAL PAIN 40 0.0006
756 INCONTINENCE 5 0.0006
757 SKIN ULCER 12 0.0006
758 RENAL FAILURE 69 0.0006
759 DELIRIUM 15 0.0006
760 HAEMATOCRIT DECREASED 10 0.0006
761 IMMUNODEFICIENCY 5 0.0006
762 VENTRICULAR EXTRASYSTOLES 5 0.0006
763 LIGAMENT SPRAIN 4 0.0006
764 DRUG LEVEL INCREASED 7 0.0006
765 EYELID OEDEMA 6 0.0006
766 RETCHING 9 0.0006
767 WHEEZING 22 0.0006
768 CHROMATURIA 10 0.0006
769 LYMPHOCYTE COUNT DECREASED 7 0.0006
770 DYSPNOEA EXERTIONAL 14 0.0006
771 GASTROENTERITIS 6 0.0006
772 GALLBLADDER DISORDER 8 0.0006
773 AFFECTIVE DISORDER 3 0.0006
774 MYOCLONUS 5 0.0006
775 DRUG INTERACTION 65 0.0006
776 C-REACTIVE PROTEIN INCREASED 13 0.0006
777 HAEMORRHAGE 40 0.0006
778 ATAXIA 5 0.0006
779 DRUG RESISTANCE 9 0.0006
780 ASPHYXIA 3 0.0005
781 TOOTHACHE 7 0.0005
782 EYE SWELLING 14 0.0005
783 POLYNEUROPATHY 4 0.0005
784 DYSKINESIA 16 0.0005
785 PULMONARY CONGESTION 5 0.0005
786 GASTROINTESTINAL HAEMORRHAGE 37 0.0005
787 ERYTHEMA 78 0.0005
788 INADEQUATE ANALGESIA 4 0.0005
789 LIVER FUNCTION TEST ABNORMAL 13 0.0005
790 HAEMOPTYSIS 11 0.0005
791 CONSTIPATION 73 0.0005
792 BONE PAIN 22 0.0005
793 HALLUCINATION, VISUAL 7 0.0005
794 LUNG DISORDER 17 0.0005
795 CARDIAC FAILURE 29 0.0005
796 HYPOTONIA 4 0.0005
797 CRYING 15 0.0005
798 PAIN IN JAW 11 0.0005
799 DERMATITIS ALLERGIC 4 0.0005
800 THROAT IRRITATION 15 0.0005
801 SYNCOPE 37 0.0005
802 FLUSHING 40 0.0005
803 FEELING COLD 10 0.0005
804 HEAD INJURY 11 0.0005
805 BLINDNESS UNILATERAL 5 0.0005
806 RECTAL HAEMORRHAGE 16 0.0005
807 NAUSEA 274 0.0005
808 HAEMATOCHEZIA 17 0.0005
809 BLOOD CHOLESTEROL INCREASED 16 0.0005
810 POST PROCEDURAL COMPLICATION 7 0.0005
811 GASTRIC ULCER 7 0.0005
812 CHEST DISCOMFORT 33 0.0005
813 CONFUSIONAL STATE 56 0.0005
814 SPLENOMEGALY 4 0.0005
815 MEDICATION ERROR 19 0.0005
816 COMPLICATION ASSOCIATED WITH DEVICE 4 0.0005
817 HYPOMAGNESAEMIA 4 0.0005
818 RESPIRATORY DEPRESSION 4 0.0005
819 CHOKING 6 0.0004
820 PAIN IN EXTREMITY 97 0.0004
821 RASH ERYTHEMATOUS 13 0.0004
822 CARDIOMYOPATHY 5 0.0004
823 NEUROLEPTIC MALIGNANT SYNDROME 4 0.0004
824 HEADACHE 196 0.0004
825 CARDIOGENIC SHOCK 4 0.0004
826 PERITONITIS 7 0.0004
827 NERVOUS SYSTEM DISORDER 11 0.0004
828 DYSSTASIA 9 0.0004
829 DRUG ERUPTION 5 0.0004
830 DISEASE RECURRENCE 7 0.0004
831 OSTEOMYELITIS 6 0.0004
832 DYSPHAGIA 28 0.0004
833 BLOOD PRESSURE FLUCTUATION 7 0.0004
834 CONVULSION 24 0.0004
835 DYSPNOEA 167 0.0004
836 BLOOD POTASSIUM DECREASED 9 0.0004
837 BODY TEMPERATURE DECREASED 3 0.0004
838 HEART RATE DECREASED 10 0.0004
839 BLOOD COUNT ABNORMAL 7 0.0004
840 WHITE BLOOD CELL COUNT INCREASED 12 0.0004
841 NO THERAPEUTIC RESPONSE 5 0.0004
842 DIARRHOEA 171 0.0004
843 ORTHOSTATIC HYPOTENSION 5 0.0004
844 PERIPHERAL COLDNESS 4 0.0004
845 OEDEMA PERIPHERAL 39 0.0004
846 SOMNOLENCE 57 0.0004
847 ABNORMAL BEHAVIOUR 13 0.0004
848 CARDIOMEGALY 4 0.0004
849 LEUKOCYTOSIS 5 0.0004
850 ASTHENIA 102 0.0004
851 AFFECT LABILITY 3 0.0004
852 DISORIENTATION 12 0.0004
853 CHEST PAIN 53 0.0004
854 IRRITABILITY 18 0.0004
855 BACK PAIN 62 0.0004
856 ABDOMINAL PAIN LOWER 7 0.0004
857 THERAPEUTIC RESPONSE DECREASED 15 0.0004
858 THERAPY CESSATION 12 0.0004
859 ELECTROCARDIOGRAM QT PROLONGED 9 0.0004
860 PRESYNCOPE 6 0.0004
861 OFF LABEL USE 154 0.0004
862 BLOOD URINE PRESENT 5 0.0004
863 FLUID RETENTION 13 0.0003
864 LABORATORY TEST ABNORMAL 7 0.0003
865 COGNITIVE DISORDER 11 0.0003
866 URINARY RETENTION 8 0.0003
867 HYPERHIDROSIS 32 0.0003
868 BLOOD POTASSIUM INCREASED 4 0.0003
869 PROTEINURIA 4 0.0003
870 DYSURIA 9 0.0003
871 FLATULENCE 13 0.0003
872 LOSS OF CONSCIOUSNESS 31 0.0003
873 RENAL IMPAIRMENT 18 0.0003
874 PSYCHOTIC DISORDER 7 0.0003
875 SEROTONIN SYNDROME 4 0.0003
876 DYSTONIA 5 0.0003
877 RASH 89 0.0003
878 RED BLOOD CELL COUNT DECREASED 6 0.0003
879 SWELLING 19 0.0003
880 TREMOR 38 0.0003
881 MENORRHAGIA 6 0.0003
882 RENAL INJURY 8 0.0003
883 BLOOD CREATINE PHOSPHOKINASE INCREASED 7 0.0003
884 RESPIRATORY ARREST 7 0.0003
885 ABDOMINAL PAIN UPPER 42 0.0003
886 EYE PAIN 10 0.0003
887 COMA 10 0.0003
888 MALIGNANT NEOPLASM PROGRESSION 18 0.0003
889 CONJUNCTIVITIS 3 0.0003
890 URINARY INCONTINENCE 6 0.0003
891 WEIGHT DECREASED 53 0.0003
892 DEATH 158 0.0003
893 RENAL DISORDER 9 0.0003
894 GAIT DISTURBANCE 38 0.0003
895 LACRIMATION INCREASED 5 0.0003
896 CEREBROVASCULAR ACCIDENT 36 0.0003
897 RASH GENERALISED 7 0.0003
898 PARAESTHESIA 30 0.0003
899 WOUND 4 0.0003
900 GASTROINTESTINAL DISORDER 13 0.0003
901 DRUG ADMINISTRATION ERROR 8 0.0003
902 SPEECH DISORDER 10 0.0003
903 MOVEMENT DISORDER 6 0.0003
904 CONTUSION 17 0.0003
905 FEELING HOT 11 0.0003
906 ACUTE MYOCARDIAL INFARCTION 6 0.0003
907 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 4 0.0003
908 RASH PRURITIC 9 0.0002
909 EMOTIONAL DISORDER 6 0.0002
910 FAECES DISCOLOURED 4 0.0002
911 HYPOTHYROIDISM 5 0.0002
912 BLOOD GLUCOSE INCREASED 35 0.0002
913 PRURITUS 55 0.0002
914 LYMPHADENOPATHY 6 0.0002
915 PRODUCTIVE COUGH 7 0.0002
916 RENAL FAILURE ACUTE 10 0.0002
917 PRURITUS GENERALISED 5 0.0002
918 FALL 54 0.0002
919 EMOTIONAL DISTRESS 15 0.0002
920 CIRCULATORY COLLAPSE 3 0.0002
921 NASAL CONGESTION 8 0.0002
922 URINARY TRACT INFECTION 25 0.0002
923 DIZZINESS 77 0.0002
924 MALAISE 70 0.0002
925 DISEASE PROGRESSION 15 0.0002
926 PAIN 85 0.0002
927 TINNITUS 7 0.0002
928 SKIN DISCOLOURATION 7 0.0002
929 BLOOD PRESSURE INCREASED 22 0.0002
930 FATIGUE 105 0.0002
931 ABASIA 5 0.0002
932 NEPHROLITHIASIS 6 0.0002
933 ADVERSE EVENT 13 0.0002
934 HYPOAESTHESIA 21 0.0002
935 SKIN DISORDER 4 0.0002
936 SUICIDAL IDEATION 13 0.0002
937 CONDITION AGGRAVATED 33 0.0002
938 MUSCULOSKELETAL STIFFNESS 11 0.0002
939 EXTRAPYRAMIDAL DISORDER 4 0.0002
940 ANXIETY 38 0.0002
941 FOETAL EXPOSURE DURING PREGNANCY 10 0.0002
942 HIP FRACTURE 4 0.0002
943 TREATMENT NONCOMPLIANCE 6 0.0002
944 NECK PAIN 7 0.0002
945 VISUAL IMPAIRMENT 14 0.0002
946 VISUAL ACUITY REDUCED 5 0.0002
947 SWOLLEN TONGUE 4 0.0002
948 DEAFNESS 3 0.0002
949 MENTAL DISORDER 5 0.0002
950 INTESTINAL OBSTRUCTION 4 0.0002
951 RHABDOMYOLYSIS 5 0.0002
952 BLISTER 6 0.0002
953 ACCIDENTAL OVERDOSE 4 0.0002
954 INTERSTITIAL LUNG DISEASE 5 0.0002
955 WEIGHT INCREASED 24 0.0002
956 MYALGIA 18 0.0001
957 PRODUCT USE ISSUE 17 0.0001
958 BRONCHITIS 8 0.0001
959 ARRHYTHMIA 5 0.0001
960 TREATMENT FAILURE 7 0.0001
961 DRUG EFFECT INCOMPLETE 5 0.0001
962 PERIPHERAL SWELLING 13 0.0001
963 BLOOD GLUCOSE DECREASED 5 0.0001
964 MUSCULOSKELETAL PAIN 6 0.0001
965 INFLUENZA 9 0.0001
966 AGGRESSION 5 0.0001
967 ARTHRALGIA 33 0.0001
968 DISTURBANCE IN ATTENTION 5 0.0001
969 UNEVALUABLE EVENT 7 0.0001
970 UNDERDOSE 6 0.0001
971 DRUG INTOLERANCE 7 0.0001
972 VISION BLURRED 11 0.0001
973 SLEEP DISORDER 5 0.0001
974 BLINDNESS 3 0.0001
975 INTENTIONAL PRODUCT USE ISSUE 5 0.0001
976 MEMORY IMPAIRMENT 10 0.0001
977 DYSPHONIA 4 0.0001
978 ABDOMINAL DISCOMFORT 11 0.0001
979 ADVERSE DRUG REACTION 5 0.0001
980 PALPITATIONS 8 0.0001
981 SKIN EXFOLIATION 5 0.0001
982 INSOMNIA 18 0.0001
983 DISCOMFORT 3 0.0001
984 MOBILITY DECREASED 4 0.0001
985 DEPRESSION 14 0.0001
986 NASOPHARYNGITIS 9 0.0001
987 DRUG EFFECT DECREASED 4 0.0001
988 ATRIAL FIBRILLATION 5 0.0001
989 GASTROOESOPHAGEAL REFLUX DISEASE 4 0.0001
990 INJURY 4 0.0001
991 FEELING ABNORMAL 12 0.0001
992 BALANCE DISORDER 4 0.0001
993 NO ADVERSE EVENT 5 0.0001
994 CHRONIC KIDNEY DISEASE 3 0.0000
995 MYOCARDIAL INFARCTION 7 0.0000
996 MUSCLE SPASMS 5 0.0000
997 DRUG INEFFECTIVE 30 0.0000