Guanylate Cyclase-C Agonist [EPC]

17709 reported adverse events

Drugs of this class: PLECANATIDE LINACLOTIDE

These side effects are most commonly reported by patients taking drugs of the Guanylate Cyclase-C Agonist [EPC] class:

# Side effect Count
0 DIARRHOEA 3750
1 DRUG INEFFECTIVE 3419
2 OFF LABEL USE 2524
3 CONSTIPATION 1205
4 NAUSEA 927
5 ABDOMINAL DISTENSION 912
6 ABDOMINAL PAIN 824
7 FATIGUE 688
8 ABDOMINAL PAIN UPPER 675
9 HEADACHE 669
See all common reactions for Guanylate Cyclase-C Agonist [EPC]

Drugs of the Guanylate Cyclase-C Agonist [EPC] class are most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 RECTAL TENESMUS 28 0.0387
1 FAECES HARD 91 0.0375
2 THERAPEUTIC PRODUCT EFFECT INCREASED 24 0.0373
3 INFREQUENT BOWEL MOVEMENTS 57 0.0320
4 GASTROINTESTINAL MOTILITY DISORDER 113 0.0313
5 FAECAL VOLUME INCREASED 11 0.0306
6 BOWEL MOVEMENT IRREGULARITY 138 0.0288
7 DYSCHEZIA 42 0.0261
8 CONTRAINDICATED DRUG PRESCRIBED 7 0.0247
9 GASTROINTESTINAL HYPERMOTILITY 7 0.0236
See all enriched reactions for Guanylate Cyclase-C Agonist [EPC]