Drug Side Effects

Nonsteroidal Anti-inflammatory Drug [EPC]

Nonsteroidal Anti-inflammatory Drug [EPC] was reported 1251394 times

Drugs of the Nonsteroidal Anti-inflammatory Drug [EPC] class are most commonly taken among patients reporting these side effects:

# Drug class Count Frequency
0 LUPUS VULGARIS 847 0.8320
1 ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE 5476 0.8236
2 DUODENAL ULCER PERFORATION 5413 0.8000
3 SWOLLEN JOINT COUNT INCREASED 2256 0.7963
4 RHEUMATIC FEVER 3168 0.7956
5 DEEP VEIN THROMBOSIS POSTOPERATIVE 1361 0.7799
6 FACET JOINT SYNDROME 2038 0.7368
7 BLOOD PRESSURE DIASTOLIC ABNORMAL 1702 0.6822
8 RHEUMATOID FACTOR POSITIVE 3661 0.6668
9 BLOOD PRESSURE SYSTOLIC ABNORMAL 1601 0.6660
10 ADJUSTMENT DISORDER WITH DEPRESSED MOOD 1157 0.6350
11 DISLOCATION OF VERTEBRA 1220 0.6106
12 MUSCLE INJURY 4572 0.5990
13 EXPOSURE TO TOXIC AGENT 1654 0.5820
14 HELICOBACTER INFECTION 5496 0.5791
15 PEMPHIGUS 6707 0.5746
16 HAND DEFORMITY 7048 0.5681
17 X-RAY ABNORMAL 927 0.5544
18 C-REACTIVE PROTEIN ABNORMAL 3323 0.5519
19 SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE 3245 0.5387
20 SYNOVITIS 9239 0.5339
21 FOLLICULITIS 5046 0.5266
22 NEPHROGENIC ANAEMIA 2278 0.4995
23 PERIPHERAL VENOUS DISEASE 1800 0.4919
24 HYPERPARATHYROIDISM SECONDARY 1166 0.4761
25 PERICARDITIS 7217 0.4616
26 REBOUND ACID HYPERSECRETION 1214 0.4012
27 RED BLOOD CELL SEDIMENTATION RATE ABNORMAL 840 0.3718
28 BONE EROSION 1240 0.3671
29 BURSITIS 4155 0.3642
30 DRUG TOLERANCE DECREASED 937 0.3565
31 GLOSSODYNIA 7560 0.3553
32 CONTRAINDICATED PRODUCT ADMINISTERED 9966 0.3472
33 TENOSYNOVITIS 896 0.3352
34 DUODENAL ULCER HAEMORRHAGE 924 0.3348
35 HYPERCHOLESTEROLAEMIA 2992 0.3319
36 GRIP STRENGTH DECREASED 2744 0.3309
37 RHEUMATOID NODULE 890 0.3267
38 JOINT RANGE OF MOTION DECREASED 4130 0.3255
39 UPPER GASTROINTESTINAL HAEMORRHAGE 5139 0.3155
40 IRRITABLE BOWEL SYNDROME 6324 0.3112
41 DUODENAL ULCER 2096 0.3094
42 WOUND 7957 0.3012
43 RED BLOOD CELL SEDIMENTATION RATE INCREASED 3203 0.2990
44 BLOOD PRESSURE DIASTOLIC DECREASED 2114 0.2940
45 GASTRIC ULCER HAEMORRHAGE 1585 0.2927
46 FIBROMYALGIA 6764 0.2915
47 WOUND INFECTION 2958 0.2893
48 GASTRITIS EROSIVE 1272 0.2829
49 ONYCHOMYCOSIS 1163 0.2811
50 LIP DRY 2323 0.2782
51 ULCER HAEMORRHAGE 1810 0.2779
52 ONYCHOMADESIS 1068 0.2770
53 CORONARY ARTERY STENOSIS 1354 0.2763
54 LOWER GASTROINTESTINAL HAEMORRHAGE 1957 0.2714
55 HAEMORRHAGIC ANAEMIA 1189 0.2702
56 DRUG EFFECTIVE FOR UNAPPROVED INDICATION 7487 0.2690
57 CAROTID ARTERY OCCLUSION 938 0.2671
58 BLOOD PRESSURE DIASTOLIC INCREASED 1188 0.2664
59 BLOOD PRESSURE SYSTOLIC INCREASED 5027 0.2662
60 ACUTE HEPATIC FAILURE 3411 0.2638
61 ANGINA UNSTABLE 1678 0.2623
62 END STAGE RENAL DISEASE 4641 0.2586
63 CAROTID ARTERY STENOSIS 876 0.2576
64 BREAST CANCER STAGE III 1548 0.2562
65 GASTRIC ULCER 4697 0.2555
66 SCIATICA 3793 0.2520
67 SYSTEMIC LUPUS ERYTHEMATOSUS 8395 0.2505
68 ARTHROPATHY 13365 0.2487
69 IMPAIRED HEALING 7792 0.2477
70 CORONARY ARTERY DISEASE 7348 0.2467
71 EXOSTOSIS 2159 0.2460
72 FINGER DEFORMITY 1145 0.2447
73 CHOLECYSTITIS CHRONIC 1613 0.2422
74 LIVER INJURY 5363 0.2384
75 OBESITY 3627 0.2377
76 BLEPHAROSPASM 1358 0.2372
77 OSTEOARTHRITIS 9658 0.2367
78 GASTROINTESTINAL HAEMORRHAGE 19233 0.2357
79 BLOOD PRESSURE FLUCTUATION 5448 0.2346
80 ARTERIOSCLEROSIS CORONARY ARTERY 1482 0.2325
81 INFUSION RELATED REACTION 14570 0.2322
82 GASTRIC HAEMORRHAGE 2612 0.2317
83 SYNOVIAL CYST 1043 0.2316
84 LIVE BIRTH 1823 0.2313
85 LABELLED DRUG-DRUG INTERACTION MEDICATION ERROR 2004 0.2294
86 SPINAL OSTEOARTHRITIS 1951 0.2294
87 ANKYLOSING SPONDYLITIS 2834 0.2290
88 MELAENA 4859 0.2283
89 CREATININE RENAL CLEARANCE DECREASED 880 0.2237
90 BODY TEMPERATURE DECREASED 2145 0.2224
91 PSORIATIC ARTHROPATHY 8414 0.2224
92 TRICUSPID VALVE INCOMPETENCE 1662 0.2222
93 CORONARY ARTERY OCCLUSION 2942 0.2198
94 INFUSION SITE SWELLING 1258 0.2181
95 INTERVERTEBRAL DISC DEGENERATION 1966 0.2174
96 RHEUMATOID ARTHRITIS 23528 0.2173
97 FOOT DEFORMITY 2315 0.2162
98 LOWER RESPIRATORY TRACT INFECTION 9197 0.2162
99 AUTOIMMUNE DISORDER 1910 0.2155
100 CHRONIC KIDNEY DISEASE 16020 0.2146
101 ACUTE MYOCARDIAL INFARCTION 6144 0.2144
102 WALKING AID USER 1354 0.2135
103 C-REACTIVE PROTEIN INCREASED 7432 0.2132
104 POLYARTHRITIS 1053 0.2109
105 TYPE 2 DIABETES MELLITUS 6824 0.2099
106 DIVERTICULUM 1477 0.2082
107 PRE-EXISTING CONDITION IMPROVED 1286 0.2079
108 MITRAL VALVE INCOMPETENCE 2244 0.2071
109 TUBULOINTERSTITIAL NEPHRITIS 3694 0.2064
110 BENIGN PROSTATIC HYPERPLASIA 1024 0.2056
111 HAEMATEMESIS 4992 0.2039
112 NAIL DISORDER 1670 0.2033
113 HYPERLIPIDAEMIA 2352 0.2032
114 IRON DEFICIENCY 847 0.2023
115 THERAPEUTIC PRODUCT EFFECT DECREASED 8440 0.2018
116 JOINT EFFUSION 1351 0.2015
117 POISONING DELIBERATE 1717 0.2003
118 BLOOD CHOLESTEROL INCREASED 8911 0.1990
119 ATELECTASIS 1864 0.1989
120 CORONARY ARTERIAL STENT INSERTION 969 0.1986
121 BREATH SOUNDS ABNORMAL 932 0.1979
122 RENAL TUBULAR NECROSIS 1843 0.1964
123 JOINT SWELLING 22539 0.1957
124 RALES 1095 0.1956
125 IRON DEFICIENCY ANAEMIA 1689 0.1930
126 ULCER 2955 0.1929
127 HEPATIC CYTOLYSIS 2082 0.1927
128 METABOLIC ACIDOSIS 5776 0.1925
129 TOXIC EPIDERMAL NECROLYSIS 2772 0.1921
130 INFUSION SITE ERYTHEMA 1469 0.1896
131 PULMONARY FIBROSIS 3435 0.1890
132 HAEMORRHAGIC STROKE 1429 0.1878
133 INFUSION SITE PAIN 2265 0.1871
134 BRONCHIECTASIS 1171 0.1869
135 HEPATIC ENZYME INCREASED 12071 0.1863
136 SPINAL COLUMN STENOSIS 880 0.1860
137 MUSCULOSKELETAL STIFFNESS 15619 0.1853
138 COAGULOPATHY 2963 0.1852
139 SLEEP APNOEA SYNDROME 3406 0.1843
140 RENAL FAILURE ACUTE 7814 0.1840
141 PERIPHERAL VASCULAR DISORDER 922 0.1828
142 TENDERNESS 1844 0.1825
143 CARDIAC MURMUR 1541 0.1823
144 ANGINA PECTORIS 5097 0.1823
145 HIATUS HERNIA 2272 0.1815
146 RENAL CYST 1391 0.1815
147 RENAL FAILURE CHRONIC 1395 0.1813
148 ARTERIOSCLEROSIS 1653 0.1813
149 HIP ARTHROPLASTY 2595 0.1812
150 MULTIPLE DRUG OVERDOSE 897 0.1804
151 ARTERIAL OCCLUSIVE DISEASE 1368 0.1792
152 JOINT DISLOCATION 1801 0.1790
153 DIABETIC NEUROPATHY 856 0.1787
154 SEASONAL ALLERGY 2382 0.1786
155 MYOCARDIAL ISCHAEMIA 1989 0.1785
156 GASTRITIS 4498 0.1782
157 SUBARACHNOID HAEMORRHAGE 1748 0.1780
158 DRUG INTOLERANCE 16270 0.1775
159 BLISTER 9473 0.1771
160 NIGHT SWEATS 5442 0.1771
161 BACK INJURY 1817 0.1768
162 ACUTE KIDNEY INJURY 25542 0.1765
163 HAEMATOCRIT DECREASED 3394 0.1750
164 ABDOMINAL TENDERNESS 830 0.1747
165 COELIAC DISEASE 1634 0.1740
166 TRANSIENT ISCHAEMIC ATTACK 5681 0.1736
167 HEART RATE DECREASED 5904 0.1733
168 SINUSITIS 17079 0.1731
169 PERIORBITAL OEDEMA 855 0.1725
170 CARDIOMEGALY 2072 0.1716
171 SWELLING 15239 0.1708
172 DISCOMFORT 9746 0.1703
173 FOOD ALLERGY 1198 0.1698
174 ANGIOEDEMA 7160 0.1695
175 MUSCULOSKELETAL PAIN 8715 0.1693
176 MULTIPLE ALLERGIES 1275 0.1693
177 FLUSHING 16633 0.1687
178 SHOCK HAEMORRHAGIC 1293 0.1680
179 ECCHYMOSIS 1113 0.1680
180 BLOOD UREA INCREASED 2742 0.1679
181 KNEE ARTHROPLASTY 3297 0.1675
182 EAR PAIN 3126 0.1671
183 RECTAL HAEMORRHAGE 6922 0.1668
184 CORONARY ARTERY BYPASS 934 0.1668
185 PROTHROMBIN TIME PROLONGED 984 0.1668
186 FLANK PAIN 1492 0.1667
187 INTENTIONAL OVERDOSE 10025 0.1661
188 HEPATITIS ACUTE 1037 0.1659
189 HYPOVOLAEMIA 931 0.1657
190 RESPIRATORY RATE INCREASED 1394 0.1634
191 ARTHRITIS 12346 0.1631
192 LARYNGITIS 1687 0.1625
193 DRUG TOXICITY 2214 0.1624
194 VASCULITIS 1805 0.1618
195 WHEEZING 9066 0.1617
196 MOBILITY DECREASED 11025 0.1612
197 PHARYNGITIS 1919 0.1598
198 INFLAMMATION 7741 0.1591
199 ROTATOR CUFF SYNDROME 1986 0.1590
200 GOUT 2736 0.1588
201 NECK PAIN 8506 0.1582
202 BLOOD CALCIUM DECREASED 1723 0.1580
203 STOMATITIS 9166 0.1580
204 INTERVERTEBRAL DISC PROTRUSION 3347 0.1576
205 GAIT INABILITY 4878 0.1571
206 ACUTE CORONARY SYNDROME 1273 0.1570
207 FAECES DISCOLOURED 3268 0.1570
208 COMPLETED SUICIDE 12625 0.1569
209 GASTROOESOPHAGEAL REFLUX DISEASE 11948 0.1567
210 LOWER LIMB FRACTURE 2824 0.1564
211 BODY HEIGHT DECREASED 1651 0.1561
212 DRUG-INDUCED LIVER INJURY 4440 0.1551
213 TROPONIN INCREASED 1101 0.1551
214 INCREASED TENDENCY TO BRUISE 1385 0.1551
215 MENISCUS INJURY 916 0.1549
216 CONTUSION 14230 0.1545
217 ACIDOSIS 1139 0.1540
218 PRESCRIBED OVERDOSE 2862 0.1540
219 MULTIPLE INJURIES 963 0.1537
220 CHOLECYSTITIS ACUTE 836 0.1535
221 ORTHOSTATIC HYPOTENSION 2568 0.1530
222 NERVE COMPRESSION 1350 0.1530
223 JOINT STIFFNESS 3853 0.1528
224 VITAMIN D DEFICIENCY 1418 0.1526
225 SPUTUM DISCOLOURED 1375 0.1524
226 MUSCLE SPASTICITY 1834 0.1519
227 DYSPNOEA EXERTIONAL 5416 0.1518
228 BODY TEMPERATURE INCREASED 3002 0.1516
229 LEFT VENTRICULAR DYSFUNCTION 957 0.1514
230 MACULAR DEGENERATION 1720 0.1512
231 RENAL INJURY 4433 0.1508
232 OESOPHAGITIS 1575 0.1508
233 ATRIAL FLUTTER 1157 0.1506
234 UPPER RESPIRATORY TRACT INFECTION 6639 0.1505
235 MYOSITIS 1277 0.1505
236 INTENTIONAL PRODUCT USE ISSUE 12596 0.1504
237 OEDEMA 7791 0.1503
238 CARPAL TUNNEL SYNDROME 2028 0.1502
239 PERIPHERAL SWELLING 21890 0.1500
240 HAEMATURIA 4941 0.1491
241 LYMPHOEDEMA 978 0.1490
242 FACIAL PAIN 1268 0.1489
243 DRUG HYPERSENSITIVITY 27833 0.1482
244 POOR VENOUS ACCESS 1455 0.1478
245 HEART RATE IRREGULAR 3255 0.1478
246 JOINT INJURY 3028 0.1476
247 MAJOR DEPRESSION 1036 0.1473
248 RHINITIS 1134 0.1472
249 MYOCARDIAL INFARCTION 25172 0.1470
250 ELECTROCARDIOGRAM ABNORMAL 1125 0.1470
251 EAR INFECTION 3712 0.1466
252 OBSTRUCTIVE AIRWAYS DISORDER 1574 0.1466
253 SPINAL PAIN 1644 0.1463
254 ABDOMINAL DISCOMFORT 23239 0.1458
255 MUSCULOSKELETAL CHEST PAIN 2159 0.1458
256 HEPATIC STEATOSIS 2582 0.1457
257 OSTEOPENIA 2150 0.1456
258 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 6524 0.1453
259 TOXICITY TO VARIOUS AGENTS 23056 0.1451
260 CHOLELITHIASIS 4545 0.1450
261 IMMUNODEFICIENCY 1979 0.1436
262 SINUS BRADYCARDIA 1335 0.1434
263 VENTRICULAR EXTRASYSTOLES 1439 0.1433
264 CARDIOVASCULAR DISORDER 3571 0.1433
265 TOOTH INFECTION 1809 0.1430
266 INJURY 9796 0.1424
267 WEIGHT FLUCTUATION 1408 0.1423
268 HAEMATOMA 3579 0.1423
269 TOOTH ABSCESS 1406 0.1419
270 OSTEOPOROSIS 5597 0.1409
271 HYPERKALAEMIA 4698 0.1408
272 SKIN LACERATION 1432 0.1407
273 OXYGEN SATURATION DECREASED 7413 0.1404
274 INFUSION SITE EXTRAVASATION 841 0.1404
275 SCOLIOSIS 838 0.1404
276 VENTRICULAR FIBRILLATION 1497 0.1403
277 CHEST PAIN 25051 0.1402
278 INTERNATIONAL NORMALISED RATIO INCREASED 3940 0.1398
279 VENTRICULAR TACHYCARDIA 2222 0.1398
280 LEUKOCYTOSIS 2411 0.1397
281 RENAL FAILURE 18119 0.1395
282 DYSPEPSIA 13017 0.1394
283 MUSCULOSKELETAL DISCOMFORT 2293 0.1392
284 GROIN PAIN 1182 0.1391
285 HAEMORRHAGE INTRACRANIAL 2019 0.1388
286 ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS 1021 0.1386
287 SINUS CONGESTION 1795 0.1380
288 OEDEMA PERIPHERAL 16289 0.1378
289 ORAL CANDIDIASIS 1696 0.1372
290 PULMONARY CONGESTION 1748 0.1371
291 CARDIAC FAILURE CONGESTIVE 10860 0.1371
292 SPINAL DISORDER 1253 0.1371
293 GALLBLADDER DISORDER 2360 0.1370
294 SUBDURAL HAEMATOMA 1891 0.1367
295 POSTOPERATIVE WOUND INFECTION 880 0.1366
296 POST-TRAUMATIC STRESS DISORDER 876 0.1364
297 GENERAL PHYSICAL HEALTH DETERIORATION 14794 0.1364
298 BACK DISORDER 2142 0.1362
299 LIGAMENT SPRAIN 1284 0.1361
300 PRODUCT ADMINISTRATION INTERRUPTED 980 0.1361
301 SLEEP DISORDER 9010 0.1358
302 MUSCLE STRAIN 1127 0.1356
303 COLITIS ISCHAEMIC 863 0.1355
304 LIVER FUNCTION TEST INCREASED 2706 0.1350
305 BLOOD ALBUMIN DECREASED 1023 0.1349
306 FEELING HOT 7977 0.1349
307 RESPIRATORY TRACT INFECTION 3315 0.1347
308 HAEMATOCHEZIA 7064 0.1347
309 TASTE DISORDER 2488 0.1345
310 HYPERTENSION 27301 0.1344
311 GASTROINTESTINAL DISORDER 11091 0.1343
312 PULMONARY MASS 1906 0.1341
313 HEPATOTOXICITY 2820 0.1338
314 STEVENS-JOHNSON SYNDROME 2884 0.1338
315 HEMIPARESIS 2195 0.1338
316 BRONCHITIS 9608 0.1337
317 BLOOD URINE PRESENT 2453 0.1336
318 POLYP 842 0.1336
319 HAEMORRHOIDS 2512 0.1336
320 NEURALGIA 3079 0.1333
321 TENDONITIS 2004 0.1330
322 CARDIOGENIC SHOCK 1798 0.1330
323 HAEMOPTYSIS 3571 0.1329
324 NOCTURIA 1535 0.1326
325 NEPHROPATHY 1209 0.1326
326 LUPUS-LIKE SYNDROME 1139 0.1326
327 SENSORY LOSS 1028 0.1323
328 INTERNAL HAEMORRHAGE 1458 0.1322
329 RIB FRACTURE 2597 0.1320
330 LIP SWELLING 4195 0.1320
331 BLOOD PRESSURE INCREASED 19373 0.1318
332 PRODUCTIVE COUGH 5875 0.1317
333 ECONOMIC PROBLEM 2011 0.1315
334 HEMIPLEGIA 1058 0.1314
335 CYSTITIS 4062 0.1314
336 ARTHRALGIA 51758 0.1311
337 VITAMIN D DECREASED 1079 0.1311
338 ACUTE RESPIRATORY FAILURE 2376 0.1308
339 ATRIAL FIBRILLATION 12223 0.1307
340 FULL BLOOD COUNT ABNORMAL 1303 0.1302
341 MICTURITION URGENCY 1405 0.1302
342 URINE OUTPUT DECREASED 1098 0.1300
343 DELIRIUM 4281 0.1298
344 CELLULITIS 6295 0.1295
345 BLOOD CREATININE INCREASED 8173 0.1295
346 ISCHAEMIC STROKE 2224 0.1294
347 DIVERTICULITIS 3408 0.1293
348 PLATELET COUNT INCREASED 1619 0.1292
349 UROSEPSIS 1132 0.1291
350 DEEP VEIN THROMBOSIS 8153 0.1289
351 SINUS TACHYCARDIA 1759 0.1287
352 BLOOD POTASSIUM INCREASED 2003 0.1286
353 HAEMOGLOBIN DECREASED 12761 0.1286
354 RHABDOMYOLYSIS 5105 0.1281
355 BACK PAIN 28597 0.1281
356 SUPRAVENTRICULAR TACHYCARDIA 1180 0.1279
357 BLOOD IRON DECREASED 1423 0.1277
358 HYPOKALAEMIA 5579 0.1273
359 MUSCULAR WEAKNESS 13882 0.1273
360 SKIN ULCER 3155 0.1272
361 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 6345 0.1272
362 EMPHYSEMA 1243 0.1271
363 BASAL CELL CARCINOMA 1907 0.1270
364 CONFUSIONAL STATE 19727 0.1267
365 NASOPHARYNGITIS 22276 0.1265
366 ALANINE AMINOTRANSFERASE INCREASED 7456 0.1263
367 BLOOD MAGNESIUM DECREASED 1041 0.1262
368 DEPRESSED LEVEL OF CONSCIOUSNESS 4761 0.1261
369 ABDOMINAL PAIN UPPER 24618 0.1259
370 STENT PLACEMENT 970 0.1258
371 ANAPHYLACTIC REACTION 6531 0.1257
372 THROAT IRRITATION 5338 0.1256
373 HEPATITIS 3083 0.1255
374 LOCALISED INFECTION 2917 0.1255
375 DRY MOUTH 9687 0.1254
376 UPPER-AIRWAY COUGH SYNDROME 973 0.1254
377 HYPOAESTHESIA 18086 0.1254
378 TOOTHACHE 2177 0.1253
379 FOOT FRACTURE 2295 0.1251
380 ANURIA 1050 0.1250
381 ARTHROPOD BITE 882 0.1245
382 MOUTH ULCERATION 2493 0.1243
383 EPISTAXIS 8926 0.1241
384 GASTROENTERITIS 1730 0.1241
385 SUICIDE ATTEMPT 7242 0.1239
386 HYPOTHERMIA 1205 0.1236
387 BLOOD ALKALINE PHOSPHATASE INCREASED 2975 0.1235
388 PAIN IN EXTREMITY 35091 0.1233
389 CHOLECYSTITIS 1393 0.1233
390 SWOLLEN TONGUE 3694 0.1230
391 GINGIVAL PAIN 933 0.1227
392 HYPOXIA 4109 0.1226
393 DRUG INTERACTION 18647 0.1224
394 MIGRAINE 11029 0.1223
395 LUNG INFILTRATION 1064 0.1223
396 DIZZINESS POSTURAL 1103 0.1221
397 PRESYNCOPE 2810 0.1220
398 RED BLOOD CELL COUNT DECREASED 3360 0.1220
399 BONE DISORDER 2177 0.1219
400 TONGUE DISORDER 864 0.1219
401 NEPHROLITHIASIS 5299 0.1217
402 POST PROCEDURAL HAEMORRHAGE 1364 0.1217
403 NODULE 1526 0.1213
404 HYPERCALCAEMIA 1429 0.1212
405 PHOTOPHOBIA 2166 0.1211
406 CONCUSSION 896 0.1210
407 PARAESTHESIA ORAL 1657 0.1209
408 ROAD TRAFFIC ACCIDENT 4852 0.1206
409 HYPOTENSION 23148 0.1206
410 CEREBRAL HAEMORRHAGE 4141 0.1205
411 MENTAL STATUS CHANGES 3226 0.1204
412 HYPOMAGNESAEMIA 1589 0.1203
413 BLOOD SODIUM DECREASED 2169 0.1203
414 LIVER DISORDER 5101 0.1203
415 SINUS DISORDER 2286 0.1203
416 ASPARTATE AMINOTRANSFERASE INCREASED 6129 0.1202
417 GLOMERULAR FILTRATION RATE DECREASED 1366 0.1202
418 CYST 1439 0.1201
419 DYSSTASIA 3393 0.1201
420 LUNG DISORDER 5620 0.1200
421 PRESCRIBED UNDERDOSE 2267 0.1199
422 LIVER FUNCTION TEST ABNORMAL 3401 0.1197
423 ADRENAL INSUFFICIENCY 1340 0.1195
424 INFECTION 16378 0.1193
425 HYPONATRAEMIA 6435 0.1191
426 GASTROINTESTINAL PAIN 1238 0.1190
427 PETECHIAE 1172 0.1190
428 ILL-DEFINED DISORDER 6945 0.1189
429 UNRESPONSIVE TO STIMULI 2915 0.1189
430 TINNITUS 5249 0.1186
431 ANAEMIA 21692 0.1182
432 RESTLESS LEGS SYNDROME 2073 0.1180
433 AORTIC ANEURYSM 874 0.1179
434 GASTROENTERITIS VIRAL 2027 0.1178
435 LIMB INJURY 3048 0.1177
436 COORDINATION ABNORMAL 1603 0.1177
437 APHTHOUS ULCER 852 0.1175
438 PERIPHERAL COLDNESS 1551 0.1175
439 HYPERSENSITIVITY 20840 0.1173
440 TOOTH FRACTURE 1252 0.1173
441 NERVE INJURY 1262 0.1172
442 BRADYCARDIA 5993 0.1169
443 SPINAL COMPRESSION FRACTURE 970 0.1168
444 MYOPATHY 972 0.1167
445 LYMPHOCYTE COUNT DECREASED 1987 0.1165
446 NEUTROPHIL COUNT INCREASED 1153 0.1160
447 HEART RATE INCREASED 10981 0.1159
448 WHITE BLOOD CELL COUNT INCREASED 4307 0.1158
449 PURPURA 986 0.1158
450 POOR QUALITY SLEEP 2356 0.1157
451 TACHYPNOEA 1491 0.1156
452 TREATMENT FAILURE 8998 0.1156
453 ERYTHEMA MULTIFORME 1034 0.1155
454 FALL 36764 0.1155
455 TOOTH DISORDER 2498 0.1155
456 URINARY TRACT INFECTION 18733 0.1153
457 RESPIRATORY TRACT CONGESTION 1748 0.1152
458 FACE OEDEMA 1882 0.1151
459 CIRCULATORY COLLAPSE 1897 0.1151
460 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 7734 0.1150
461 PYELONEPHRITIS 947 0.1150
462 CLOSTRIDIUM DIFFICILE COLITIS 1164 0.1148
463 GENERALISED OEDEMA 1345 0.1147
464 DIPLOPIA 2842 0.1147
465 CATARACT 6463 0.1145
466 IMPAIRED GASTRIC EMPTYING 1248 0.1143
467 PULMONARY HYPERTENSION 2305 0.1143
468 CEREBROVASCULAR ACCIDENT 18754 0.1142
469 PAIN 67681 0.1142
470 HEPATIC CIRRHOSIS 2028 0.1142
471 RESPIRATORY DEPRESSION 1340 0.1142
472 COVID-19 PNEUMONIA 1305 0.1140
473 PLEURAL EFFUSION 6683 0.1140
474 PARAESTHESIA 17318 0.1140
475 ATRIOVENTRICULAR BLOCK 850 0.1138
476 DYSURIA 4033 0.1137
477 HYPOKINESIA 1581 0.1133
478 SKIN INFECTION 1202 0.1131
479 DECUBITUS ULCER 884 0.1131
480 GAIT DISTURBANCE 20910 0.1130
481 CONSTIPATION 23068 0.1128
482 LIMB DISCOMFORT 3347 0.1128
483 ABDOMINAL PAIN 25021 0.1127
484 PANCREATITIS ACUTE 2390 0.1126
485 TACHYCARDIA 9569 0.1124
486 RASH MACULO-PAPULAR 2374 0.1124
487 WRIST FRACTURE 1293 0.1123
488 BLOOD POTASSIUM DECREASED 3251 0.1123
489 DRUG ERUPTION 1880 0.1122
490 SYNCOPE 10791 0.1122
491 BALANCE DISORDER 9345 0.1122
492 EJECTION FRACTION DECREASED 1676 0.1120
493 HEPATOMEGALY 1070 0.1120
494 BLADDER DISORDER 1075 0.1120
495 PULMONARY OEDEMA 4824 0.1119
496 HEPATIC ENCEPHALOPATHY 1010 0.1118
497 PNEUMONIA 34370 0.1116
498 BRAIN OEDEMA 1347 0.1115
499 CHROMATURIA 2413 0.1114
500 OSTEOMYELITIS 1945 0.1113
501 AMNESIA 7004 0.1113
502 ELECTROLYTE IMBALANCE 1210 0.1113
503 EYELID OEDEMA 1268 0.1111
504 RESPIRATORY DISORDER 3189 0.1110
505 URTICARIA 17516 0.1109
506 DERMATITIS CONTACT 1205 0.1109
507 LACERATION 1043 0.1108
508 PULMONARY EMBOLISM 10204 0.1107
509 DENTAL CARIES 1185 0.1107
510 GASTRIC DISORDER 3809 0.1107
511 EYE INFECTION 1185 0.1106
512 POLYURIA 869 0.1106
513 BLOOD PRESSURE DECREASED 7018 0.1104
514 POST PROCEDURAL INFECTION 847 0.1102
515 URINARY INCONTINENCE 3134 0.1101
516 MOTOR DYSFUNCTION 1066 0.1100
517 CARDIOMYOPATHY 1573 0.1100
518 DYSARTHRIA 3974 0.1099
519 ANHEDONIA 2850 0.1098
520 CHEST DISCOMFORT 10658 0.1097
521 CARDIO-RESPIRATORY ARREST 4455 0.1097
522 HAEMODIALYSIS 915 0.1096
523 KIDNEY INFECTION 2060 0.1096
524 HYPERHIDROSIS 13615 0.1094
525 HYPERAESTHESIA 878 0.1092
526 DEHYDRATION 13962 0.1090
527 ANKLE FRACTURE 1627 0.1090
528 ASPIRATION 1115 0.1090
529 ASTHENIA 39276 0.1089
530 ORAL DISCOMFORT 1455 0.1088
531 SKIN LESION 2812 0.1088
532 WEIGHT DECREASED 29041 0.1086
533 CONDITION AGGRAVATED 31019 0.1086
534 BLOOD CALCIUM INCREASED 912 0.1085
535 PHARYNGEAL SWELLING 963 0.1085
536 NASAL CONGESTION 6016 0.1085
537 OROPHARYNGEAL PAIN 9620 0.1084
538 DYSPNOEA 58625 0.1082
539 RHINORRHOEA 6629 0.1082
540 HEAD DISCOMFORT 1810 0.1082
541 SPLENOMEGALY 1216 0.1082
542 JAUNDICE 2820 0.1082
543 POST PROCEDURAL COMPLICATION 2010 0.1081
544 COMA 4951 0.1080
545 SMALL INTESTINAL OBSTRUCTION 1258 0.1079
546 COUGH 28735 0.1078
547 PERICARDIAL EFFUSION 2357 0.1074
548 WEIGHT INCREASED 22729 0.1072
549 HEPATIC FAILURE 3105 0.1071
550 INCONTINENCE 1091 0.1071
551 MATERNAL EXPOSURE DURING PREGNANCY 8897 0.1071
552 PYREXIA 35540 0.1069
553 THERAPY NON-RESPONDER 4458 0.1068
554 EOSINOPHIL COUNT INCREASED 849 0.1067
555 TENDON RUPTURE 1276 0.1064
556 SWELLING FACE 6619 0.1064
557 SEROTONIN SYNDROME 1940 0.1064
558 FATIGUE 78928 0.1063
559 STRESS 7285 0.1062
560 GINGIVAL BLEEDING 1392 0.1060
561 MIDDLE INSOMNIA 1885 0.1056
562 DECREASED ACTIVITY 1079 0.1055
563 VOMITING 47123 0.1055
564 PALLOR 2774 0.1053
565 ORAL PAIN 2279 0.1053
566 BLOOD TRIGLYCERIDES INCREASED 1798 0.1053
567 HOT FLUSH 7639 0.1051
568 MULTI-ORGAN FAILURE 1819 0.1050
569 EYE PAIN 5481 0.1050
570 ANAL INCONTINENCE 870 0.1049
571 POISONING 1276 0.1047
572 TRANSAMINASES INCREASED 2225 0.1045
573 HERPES ZOSTER 5781 0.1043
574 DIZZINESS 49717 0.1043
575 BLOOD PRESSURE ABNORMAL 1965 0.1042
576 MUSCLE TWITCHING 2321 0.1042
577 INSOMNIA 26705 0.1040
578 FEELING COLD 2788 0.1040
579 PAIN IN JAW 2845 0.1039
580 MUSCLE SPASMS 18271 0.1039
581 ASTHMA 10969 0.1038
582 OROPHARYNGEAL DISCOMFORT 866 0.1038
583 MASS 1400 0.1037
584 RASH PRURITIC 5316 0.1037
585 STAPHYLOCOCCAL INFECTION 3310 0.1036
586 SECRETION DISCHARGE 1193 0.1036
587 FLUID RETENTION 5062 0.1035
588 URINARY RETENTION 3290 0.1033
589 MEDICATION ERROR 5449 0.1032
590 POLLAKIURIA 4100 0.1029
591 DRUG LEVEL INCREASED 1640 0.1028
592 LACTIC ACIDOSIS 3099 0.1026
593 SHOCK 2223 0.1026
594 APPENDICITIS 902 0.1025
595 CHILLS 11571 0.1025
596 HYPOGLYCAEMIA 4768 0.1024
597 SCAR 1691 0.1023
598 BLOOD CREATINE PHOSPHOKINASE INCREASED 2930 0.1021
599 OCULAR DISCOMFORT 1021 0.1020
600 CYTOKINE RELEASE SYNDROME 1708 0.1020
601 FULL BLOOD COUNT DECREASED 1974 0.1020
602 COLD SWEAT 1731 0.1019
603 EAR DISCOMFORT 998 0.1018
604 INITIAL INSOMNIA 994 0.1017
605 DECREASED APPETITE 22397 0.1015
606 DEPRESSION 22410 0.1014
607 HYPOPHAGIA 2434 0.1014
608 RENAL PAIN 1029 0.1012
609 VIRAL INFECTION 3190 0.1011
610 GAMMA-GLUTAMYLTRANSFERASE INCREASED 2167 0.1011
611 CHOLESTASIS 1842 0.1011
612 MYALGIA 16474 0.1011
613 LETHARGY 5588 0.1010
614 MUSCULOSKELETAL DISORDER 1868 0.1009
615 INTENTIONAL PRODUCT MISUSE 8385 0.1009
616 COGNITIVE DISORDER 4483 0.1007
617 HERNIA 1845 0.1007
618 ATAXIA 1152 0.1006
619 APHASIA 2925 0.1006
620 EATING DISORDER 2071 0.1005
621 RENAL IMPAIRMENT 8000 0.1002
622 PRODUCT USE IN UNAPPROVED INDICATION 22867 0.1002
623 BLOOD BILIRUBIN INCREASED 2612 0.1000
624 HEAD INJURY 3016 0.1000
625 ANOREXIA 1288 0.0999
626 PHARYNGEAL OEDEMA 1534 0.0999
627 SOMNOLENCE 19226 0.0998
628 PRURITUS 35172 0.0997
629 HEADACHE 59628 0.0994
630 RASH ERYTHEMATOUS 4324 0.0994
631 HYPOCALCAEMIA 1786 0.0994
632 HYPOAESTHESIA ORAL 1436 0.0993
633 NEUROPATHY PERIPHERAL 8881 0.0993
634 ENCEPHALOPATHY 2303 0.0990
635 CANDIDA INFECTION 1551 0.0988
636 PALPITATIONS 11044 0.0988
637 PNEUMONIA ASPIRATION 2353 0.0987
638 MALNUTRITION 1039 0.0987
639 UVEITIS 1269 0.0987
640 BLOOD TEST ABNORMAL 1320 0.0986
641 MUSCLE ATROPHY 1173 0.0986
642 THROMBOSIS 7663 0.0986
643 DYSPHAGIA 8889 0.0985
644 TEMPERATURE INTOLERANCE 960 0.0984
645 THROAT TIGHTNESS 2546 0.0984
646 DISORIENTATION 3772 0.0982
647 SEPTIC SHOCK 4038 0.0982
648 MUSCLE TIGHTNESS 1526 0.0982
649 BURNING SENSATION 6587 0.0979
650 ABDOMINAL DISTENSION 9660 0.0979
651 DIABETES MELLITUS INADEQUATE CONTROL 1659 0.0978
652 DYSPHONIA 5466 0.0978
653 PRURITUS GENERALISED 2117 0.0977
654 SEPSIS 10454 0.0977
655 BLOOD LACTATE DEHYDROGENASE INCREASED 1512 0.0975
656 SEDATION 2418 0.0975
657 INFLUENZA 10222 0.0974
658 CARDIAC ARREST 7752 0.0973
659 HALLUCINATION, VISUAL 1932 0.0972
660 RASH 39998 0.0972
661 PHARYNGITIS STREPTOCOCCAL 1009 0.0971
662 IMPAIRED WORK ABILITY 2007 0.0969
663 ACUTE RESPIRATORY DISTRESS SYNDROME 1637 0.0967
664 INSURANCE ISSUE 1243 0.0966
665 SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION 1358 0.0965
666 DIARRHOEA HAEMORRHAGIC 869 0.0964
667 THERAPEUTIC RESPONSE UNEXPECTED 4194 0.0964
668 HYPERSOMNIA 2640 0.0964
669 RESPIRATORY DISTRESS 2551 0.0963
670 MOVEMENT DISORDER 2994 0.0963
671 DERMATITIS ALLERGIC 1126 0.0963
672 DIARRHOEA 58798 0.0963
673 COLITIS 3422 0.0963
674 NAUSEA 72004 0.0957
675 SKIN HAEMORRHAGE 1271 0.0954
676 PHOTOSENSITIVITY REACTION 1511 0.0954
677 CHOLECYSTECTOMY 1033 0.0953
678 ALOPECIA 18035 0.0953
679 RENAL DISORDER 4282 0.0953
680 HYPERGLYCAEMIA 3321 0.0953
681 HALLUCINATION 6760 0.0952
682 BACTERAEMIA 1060 0.0950
683 HAEMORRHAGE 9520 0.0950
684 BACTERIAL INFECTION 1675 0.0949
685 RESPIRATORY FAILURE 6646 0.0949
686 ANXIETY 26053 0.0948
687 DIABETES MELLITUS 7001 0.0946
688 LYMPHADENOPATHY 3211 0.0946
689 VERTIGO 5538 0.0945
690 UPPER LIMB FRACTURE 1827 0.0945
691 MEMORY IMPAIRMENT 12505 0.0945
692 FEBRILE NEUTROPENIA 5958 0.0944
693 CONJUNCTIVITIS 1634 0.0942
694 FREQUENT BOWEL MOVEMENTS 2397 0.0942
695 LOSS OF CONSCIOUSNESS 11583 0.0941
696 CHOKING 1744 0.0941
697 ORAL HERPES 1742 0.0940
698 CEREBRAL INFARCTION 2213 0.0938
699 EOSINOPHILIA 1563 0.0938
700 HYPOTHYROIDISM 2843 0.0936
701 EYE HAEMORRHAGE 1205 0.0934
702 FLATULENCE 5014 0.0933
703 GLAUCOMA 1723 0.0930
704 DRY THROAT 897 0.0927
705 PNEUMOTHORAX 1405 0.0926
706 EYE SWELLING 3262 0.0922
707 SCRATCH 889 0.0920
708 DRUG EFFECT LESS THAN EXPECTED 1108 0.0920
709 SCAB 990 0.0917
710 KNEE OPERATION 836 0.0917
711 RETCHING 1858 0.0916
712 ACTIVITIES OF DAILY LIVING IMPAIRED 1813 0.0914
713 THYROID DISORDER 1345 0.0912
714 NEPHROPATHY TOXIC 957 0.0910
715 PRODUCT USE ISSUE 16038 0.0909
716 MULTIPLE ORGAN DYSFUNCTION SYNDROME 2346 0.0909
717 ALTERED STATE OF CONSCIOUSNESS 1860 0.0908
718 SPINAL FRACTURE 1717 0.0906
719 ADVERSE REACTION 1154 0.0906
720 ABSCESS 1387 0.0905
721 SNEEZING 1929 0.0905
722 ABDOMINAL PAIN LOWER 2186 0.0901
723 BONE PAIN 5063 0.0901
724 QUALITY OF LIFE DECREASED 1165 0.0901
725 ARRHYTHMIA 4125 0.0899
726 FEELING JITTERY 1657 0.0898
727 LOCAL SWELLING 1567 0.0897
728 TRANSFUSION 909 0.0897
729 BEDRIDDEN 1130 0.0897
730 ANAPHYLACTIC SHOCK 2175 0.0896
731 RASH PAPULAR 1939 0.0895
732 THROMBOCYTOPENIA 9516 0.0894
733 RESPIRATORY ARREST 2407 0.0891
734 SKIN DISCOLOURATION 3917 0.0890
735 ERUCTATION 1528 0.0887
736 DISABILITY 1667 0.0885
737 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 852 0.0884
738 ASCITES 2494 0.0883
739 HIP FRACTURE 2703 0.0882
740 SENSORY DISTURBANCE 1375 0.0882
741 PULMONARY THROMBOSIS 924 0.0881
742 DISSEMINATED INTRAVASCULAR COAGULATION 1202 0.0881
743 MALAISE 37255 0.0880
744 CARDIAC FAILURE 6777 0.0879
745 EXPOSURE DURING PREGNANCY 5234 0.0878
746 RASH MACULAR 2908 0.0878
747 PROTEINURIA 1557 0.0877
748 ABASIA 2167 0.0876
749 BRONCHOSPASM 1208 0.0876
750 LABORATORY TEST ABNORMAL 2471 0.0875
751 IMPAIRED QUALITY OF LIFE 1209 0.0874
752 HYPERBILIRUBINAEMIA 855 0.0873
753 INFLUENZA LIKE ILLNESS 6955 0.0873
754 EYE DISORDER 2728 0.0871
755 RESTLESSNESS 3069 0.0870
756 NIGHTMARE 2900 0.0865
757 FEAR 2276 0.0863
758 CYANOSIS 1311 0.0863
759 MYOCLONUS 991 0.0862
760 PRODUCT PRESCRIBING ERROR 1903 0.0861
761 OVARIAN CYST 841 0.0860
762 APHONIA 1146 0.0860
763 COVID-19 14741 0.0859
764 PANCREATITIS 4349 0.0858
765 HYPERTENSIVE CRISIS 917 0.0856
766 CARDIAC DISORDER 7729 0.0853
767 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 1322 0.0849
768 DISTURBANCE IN ATTENTION 4436 0.0848
769 ACCIDENTAL OVERDOSE 2960 0.0847
770 TREMOR 13541 0.0847
771 SPEECH DISORDER 4270 0.0847
772 HAIR COLOUR CHANGES 1037 0.0847
773 AGRANULOCYTOSIS 1480 0.0846
774 CLOSTRIDIUM DIFFICILE INFECTION 1735 0.0846
775 DEAFNESS 2118 0.0846
776 DRUG EFFECT INCOMPLETE 3071 0.0844
777 PNEUMONITIS 2159 0.0844
778 VISION BLURRED 10985 0.0844
779 WHITE BLOOD CELL COUNT DECREASED 8797 0.0843
780 FEEDING DISORDER 1546 0.0841
781 AGEUSIA 2015 0.0839
782 DRY EYE 3737 0.0839
783 ERYTHEMA 16444 0.0837
784 SARS-COV-2 TEST POSITIVE 1092 0.0836
785 DYSGEUSIA 6053 0.0836
786 PREMATURE DELIVERY 1297 0.0835
787 BRAIN FOG 1003 0.0834
788 PROSTATIC SPECIFIC ANTIGEN INCREASED 1118 0.0833
789 EPILEPSY 2417 0.0833
790 FEELING ABNORMAL 19337 0.0831
791 PANCYTOPENIA 4408 0.0828
792 INTESTINAL PERFORATION 888 0.0828
793 MALIGNANT MELANOMA 1067 0.0827
794 ILEUS 968 0.0824
795 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 1995 0.0822
796 SUDDEN DEATH 852 0.0821
797 MYOCARDITIS 868 0.0821
798 PLATELET COUNT DECREASED 8369 0.0820
799 FEMUR FRACTURE 2457 0.0819
800 BLINDNESS UNILATERAL 1101 0.0817
801 IMMUNE SYSTEM DISORDER 1024 0.0814
802 FUNGAL INFECTION 2600 0.0814
803 DEPRESSED MOOD 4070 0.0812
804 NERVOUSNESS 4123 0.0809
805 RASH GENERALISED 2098 0.0809
806 LACRIMATION INCREASED 2279 0.0809
807 BIPOLAR DISORDER 855 0.0806
808 BREAST PAIN 830 0.0805
809 PARANOIA 1331 0.0796
810 SKIN DISORDER 2517 0.0795
811 AGITATION 5648 0.0795
812 DELUSION 1174 0.0794
813 SPINAL OPERATION 892 0.0794
814 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 4264 0.0791
815 IMPAIRED DRIVING ABILITY 865 0.0791
816 HEPATOCELLULAR INJURY 1086 0.0789
817 PRODUCT TASTE ABNORMAL 1000 0.0788
818 PRODUCT ADMINISTRATION ERROR 1460 0.0786
819 ANOSMIA 1092 0.0785
820 HAIR TEXTURE ABNORMAL 1032 0.0785
821 MUSCLE RIGIDITY 895 0.0783
822 ELECTROCARDIOGRAM QT PROLONGED 2687 0.0783
823 THIRST 1327 0.0782
824 POLYNEUROPATHY 878 0.0781
825 OVERDOSE 16331 0.0779
826 LEUKOPENIA 3696 0.0775
827 DEMENTIA 2031 0.0771
828 FLUID OVERLOAD 1114 0.0765
829 INTENTIONAL DRUG MISUSE 1596 0.0763
830 MYDRIASIS 939 0.0761
831 ILLNESS 6889 0.0760
832 PSORIASIS 9508 0.0758
833 PREMATURE BABY 2211 0.0754
834 ACCIDENT 860 0.0753
835 MUCOSAL INFLAMMATION 1878 0.0753
836 PARALYSIS 1042 0.0753
837 BLINDNESS 2925 0.0752
838 THERAPEUTIC RESPONSE SHORTENED 2133 0.0751
839 PROCEDURAL PAIN 1934 0.0747
840 TOOTH EXTRACTION 897 0.0745
841 ERECTILE DYSFUNCTION 1823 0.0742
842 LYMPHOPENIA 991 0.0742
843 VISUAL IMPAIRMENT 8626 0.0740
844 LUNG INFECTION 1150 0.0740
845 DYSKINESIA 2861 0.0737
846 NEUTROPHIL COUNT DECREASED 2830 0.0736
847 DRUG INEFFECTIVE 92695 0.0735
848 PANIC ATTACK 2562 0.0730
849 BLOOD COUNT ABNORMAL 1108 0.0729
850 INTENTIONAL SELF-INJURY 1412 0.0728
851 HUNGER 867 0.0723
852 DERMATITIS 1395 0.0721
853 OFF LABEL USE 58474 0.0717
854 PLASMA CELL MYELOMA 2700 0.0717
855 THINKING ABNORMAL 1295 0.0713
856 INTERSTITIAL LUNG DISEASE 3273 0.0712
857 EXPIRED PRODUCT ADMINISTERED 2256 0.0710
858 ABNORMAL DREAMS 1911 0.0706
859 METASTASES TO BONE 1094 0.0704
860 HYPERTHYROIDISM 962 0.0702
861 DIALYSIS 961 0.0701
862 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 11406 0.0699
863 MENTAL DISORDER 2925 0.0698
864 INTENTIONAL DOSE OMISSION 1699 0.0698
865 MULTIPLE FRACTURES 1124 0.0697
866 TREATMENT NONCOMPLIANCE 3577 0.0696
867 DEVICE RELATED INFECTION 1035 0.0694
868 PELVIC PAIN 1184 0.0692
869 SKIN REACTION 923 0.0690
870 CONVULSION 3935 0.0687
871 VISUAL ACUITY REDUCED 2235 0.0685
872 APATHY 952 0.0684
873 FOETAL EXPOSURE DURING PREGNANCY 5292 0.0678
874 CRYING 2392 0.0677
875 DISEASE RECURRENCE 3112 0.0675
876 INCREASED APPETITE 1160 0.0671
877 MENTAL IMPAIRMENT 1565 0.0670
878 HALLUCINATION, AUDITORY 1022 0.0669
879 HEPATIC FUNCTION ABNORMAL 2352 0.0669
880 PRODUCT USE COMPLAINT 954 0.0668
881 INTESTINAL OBSTRUCTION 2365 0.0667
882 ADVERSE DRUG REACTION 5623 0.0666
883 SURGERY 3596 0.0666
884 COLITIS ULCERATIVE 2781 0.0666
885 THERAPEUTIC RESPONSE DECREASED 3814 0.0664
886 FRACTURE 1204 0.0660
887 SKIN FISSURES 1130 0.0660
888 EYE PRURITUS 2011 0.0659
889 DRUG EFFECT DECREASED 3549 0.0658
890 HYPOACUSIS 2693 0.0658
891 BLOOD GLUCOSE DECREASED 3052 0.0656
892 SKIN CANCER 1346 0.0654
893 LYMPHOMA 973 0.0651
894 PRODUCT DOSE OMISSION IN ERROR 1530 0.0648
895 PREGNANCY 1278 0.0647
896 PSYCHOTIC DISORDER 1830 0.0643
897 BLOOD GLUCOSE INCREASED 11641 0.0638
898 UNEVALUABLE EVENT 4656 0.0636
899 OCULAR HYPERAEMIA 2781 0.0636
900 GLYCOSYLATED HAEMOGLOBIN INCREASED 1527 0.0635
901 BONE DENSITY DECREASED 1954 0.0633
902 SUICIDAL IDEATION 5573 0.0633
903 NEUTROPENIA 8132 0.0629
904 PSYCHOMOTOR HYPERACTIVITY 1008 0.0626
905 CENTRAL NERVOUS SYSTEM LESION 842 0.0625
906 GENERALISED TONIC-CLONIC SEIZURE 967 0.0625
907 INCORRECT PRODUCT ADMINISTRATION DURATION 1202 0.0622
908 PRODUCT PHYSICAL ISSUE 1160 0.0618
909 INJECTION SITE HAEMATOMA 887 0.0616
910 PERITONITIS 1222 0.0615
911 COLON CANCER 879 0.0614
912 PULMONARY ARTERIAL HYPERTENSION 858 0.0607
913 PAIN OF SKIN 1574 0.0606
914 INCORRECT DRUG ADMINISTRATION DURATION 1700 0.0604
915 MULTIPLE SCLEROSIS 2809 0.0603
916 THERAPY CESSATION 2908 0.0599
917 TOOTH LOSS 1211 0.0597
918 SEIZURE 6389 0.0592
919 INJECTION SITE BRUISING 4406 0.0592
920 WRONG TECHNIQUE IN DRUG USAGE PROCESS 2146 0.0590
921 METASTASES TO LIVER 986 0.0589
922 DRUG ABUSE 4733 0.0587
923 NERVOUS SYSTEM DISORDER 1776 0.0587
924 ECZEMA 2589 0.0585
925 ANGER 1918 0.0584
926 DRUG ADMINISTRATION ERROR 1789 0.0582
927 OSTEONECROSIS OF JAW 1402 0.0579
928 IRRITABILITY 3356 0.0578
929 SKIN EXFOLIATION 4472 0.0572
930 EMOTIONAL DISTRESS 6616 0.0561
931 DISEASE PROGRESSION 6279 0.0558
932 EMOTIONAL DISORDER 1663 0.0557
933 UNDERDOSE 3886 0.0556
934 PRODUCT DOSE OMISSION ISSUE 13945 0.0555
935 MOOD ALTERED 1442 0.0555
936 DIABETIC KETOACIDOSIS 1270 0.0551
937 BLOOD GLUCOSE ABNORMAL 980 0.0551
938 MOOD SWINGS 1680 0.0545
939 AGGRESSION 2640 0.0545
940 EYE IRRITATION 2752 0.0542
941 ADVERSE EVENT 4774 0.0539
942 INCORRECT DOSE ADMINISTERED 11313 0.0537
943 ABNORMAL BEHAVIOUR 2069 0.0536
944 MULTIPLE SCLEROSIS RELAPSE 3584 0.0532
945 PRODUCT QUALITY ISSUE 6934 0.0530
946 PHARMACEUTICAL PRODUCT COMPLAINT 1357 0.0522
947 INJECTION SITE HAEMORRHAGE 3870 0.0512
948 INJECTION SITE REACTION 3337 0.0510
949 THERAPY INTERRUPTED 3160 0.0509
950 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 3627 0.0509
951 DRUG PRESCRIBING ERROR 964 0.0501
952 PRODUCT DOSE OMISSION 3317 0.0501
953 OSTEONECROSIS 1620 0.0500
954 PRODUCT AVAILABILITY ISSUE 1037 0.0499
955 DRY SKIN 6119 0.0497
956 PRODUCT SUBSTITUTION ISSUE 2680 0.0486
957 WITHDRAWAL SYNDROME 1927 0.0472
958 INJECTION SITE PRURITUS 2957 0.0468
959 VAGINAL HAEMORRHAGE 1926 0.0465
960 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 1037 0.0462
961 INJECTION SITE ERYTHEMA 5393 0.0458
962 DRUG DOSE OMISSION 7576 0.0457
963 BONE MARROW FAILURE 908 0.0456
964 MENORRHAGIA 893 0.0454
965 INJECTION SITE MASS 1592 0.0453
966 SKIN BURNING SENSATION 3010 0.0444
967 LUNG NEOPLASM MALIGNANT 1773 0.0443
968 INJECTION SITE RASH 1258 0.0442
969 NEOPLASM MALIGNANT 2788 0.0437
970 NEOPLASM PROGRESSION 1480 0.0431
971 EXTRA DOSE ADMINISTERED 1577 0.0428
972 MALIGNANT NEOPLASM PROGRESSION 4062 0.0423
973 INJECTION SITE WARMTH 833 0.0419
974 ABORTION SPONTANEOUS 1613 0.0415
975 INJECTION SITE SWELLING 2950 0.0412
976 INJECTION SITE URTICARIA 924 0.0405
977 INJECTION SITE PAIN 11491 0.0402
978 HOSPITALISATION 5598 0.0390
979 NEEDLE ISSUE 988 0.0370
980 DEATH 30020 0.0364
981 EXTRAPYRAMIDAL DISORDER 866 0.0353
982 DRUG EXPOSURE DURING PREGNANCY 1194 0.0351
983 DEVICE MALFUNCTION 2126 0.0345
984 DEVICE DISLOCATION 1374 0.0332
985 DEVICE ISSUE 2618 0.0322
986 ACNE 2366 0.0321
987 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 6113 0.0316
988 SKIN IRRITATION 1313 0.0298
989 DERMATITIS ATOPIC 1220 0.0295
990 DRUG WITHDRAWAL SYNDROME 2435 0.0280
991 BREAST CANCER 2482 0.0270
992 CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR 839 0.0262
993 DRUG DEPENDENCE 3672 0.0230
994 ACCIDENTAL EXPOSURE TO PRODUCT 2054 0.0225
995 NO ADVERSE EVENT 3730 0.0222
996 PROSTATE CANCER 1594 0.0200
997 PRODUCT STORAGE ERROR 1080 0.0133