Drug Side Effects

Nonsteroidal Anti-inflammatory Drug [EPC]

Nonsteroidal Anti-inflammatory Drug [EPC] was reported 1290786 times

Drugs of the Nonsteroidal Anti-inflammatory Drug [EPC] class are most commonly taken among patients reporting these side effects:

# Drug class Count Frequency
0 LUPUS VULGARIS 978 0.8323
1 ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE 5775 0.8232
2 DUODENAL ULCER PERFORATION 5795 0.7998
3 RHEUMATIC FEVER 3399 0.7883
4 SWOLLEN JOINT COUNT INCREASED 2404 0.7808
5 DEEP VEIN THROMBOSIS POSTOPERATIVE 1505 0.7774
6 FACET JOINT SYNDROME 2313 0.7430
7 BLOOD PRESSURE DIASTOLIC ABNORMAL 1727 0.6807
8 RHEUMATOID FACTOR POSITIVE 3814 0.6697
9 BLOOD PRESSURE SYSTOLIC ABNORMAL 1622 0.6599
10 ADJUSTMENT DISORDER WITH DEPRESSED MOOD 1273 0.6397
11 DISLOCATION OF VERTEBRA 1375 0.6259
12 EXPOSURE TO TOXIC AGENT 1949 0.6131
13 MUSCLE INJURY 4873 0.6015
14 HELICOBACTER INFECTION 5888 0.5851
15 PEMPHIGUS 7127 0.5808
16 HAND DEFORMITY 7426 0.5751
17 X-RAY ABNORMAL 984 0.5585
18 C-REACTIVE PROTEIN ABNORMAL 3523 0.5572
19 SYNOVITIS 9592 0.5385
20 SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE 3379 0.5318
21 FOLLICULITIS 5415 0.5311
22 PERIPHERAL VENOUS DISEASE 1974 0.5008
23 NEPHROGENIC ANAEMIA 2283 0.4949
24 HYPERPARATHYROIDISM SECONDARY 1170 0.4680
25 PERICARDITIS 7666 0.4661
26 REBOUND ACID HYPERSECRETION 1213 0.4007
27 BONE EROSION 1317 0.3766
28 BURSITIS 4468 0.3751
29 RED BLOOD CELL SEDIMENTATION RATE ABNORMAL 857 0.3731
30 GLOSSODYNIA 8021 0.3636
31 DRUG TOLERANCE DECREASED 983 0.3556
32 CONTRAINDICATED PRODUCT ADMINISTERED 10395 0.3492
33 HYPERCHOLESTEROLAEMIA 3234 0.3425
34 JOINT RANGE OF MOTION DECREASED 4460 0.3381
35 GRIP STRENGTH DECREASED 2907 0.3367
36 TENOSYNOVITIS 908 0.3327
37 DUODENAL ULCER HAEMORRHAGE 941 0.3317
38 RHEUMATOID NODULE 894 0.3253
39 IRRITABLE BOWEL SYNDROME 6695 0.3175
40 UPPER GASTROINTESTINAL HAEMORRHAGE 5249 0.3152
41 DUODENAL ULCER 2146 0.3082
42 WOUND 8398 0.3060
43 RED BLOOD CELL SEDIMENTATION RATE INCREASED 3333 0.3044
44 WOUND INFECTION 3241 0.3022
45 FIBROMYALGIA 7128 0.2974
46 BLOOD PRESSURE DIASTOLIC DECREASED 2157 0.2947
47 GASTRIC ULCER HAEMORRHAGE 1618 0.2935
48 LIP DRY 2585 0.2923
49 ONYCHOMYCOSIS 1242 0.2873
50 ONYCHOMADESIS 1176 0.2868
51 GASTRITIS EROSIVE 1302 0.2825
52 BREAST CANCER STAGE III 1792 0.2822
53 ULCER HAEMORRHAGE 1884 0.2820
54 CORONARY ARTERY STENOSIS 1374 0.2760
55 CAROTID ARTERY OCCLUSION 983 0.2721
56 HAEMORRHAGIC ANAEMIA 1188 0.2699
57 LOWER GASTROINTESTINAL HAEMORRHAGE 1977 0.2698
58 ACUTE HEPATIC FAILURE 3621 0.2698
59 BLOOD PRESSURE SYSTOLIC INCREASED 5150 0.2664
60 BLOOD PRESSURE DIASTOLIC INCREASED 1215 0.2655
61 DRUG EFFECTIVE FOR UNAPPROVED INDICATION 7577 0.2628
62 ANGINA UNSTABLE 1692 0.2614
63 END STAGE RENAL DISEASE 4691 0.2581
64 CAROTID ARTERY STENOSIS 891 0.2570
65 SCIATICA 4018 0.2567
66 GASTRIC ULCER 4779 0.2544
67 EXOSTOSIS 2291 0.2543
68 IMPAIRED HEALING 8225 0.2538
69 SYSTEMIC LUPUS ERYTHEMATOSUS 8836 0.2531
70 BLEPHAROSPASM 1545 0.2522
71 ARTHROPATHY 13764 0.2500
72 FINGER DEFORMITY 1184 0.2474
73 CORONARY ARTERY DISEASE 7438 0.2470
74 LIVE BIRTH 2024 0.2463
75 OBESITY 3859 0.2451
76 CHOLECYSTITIS CHRONIC 1621 0.2419
77 LIVER INJURY 5740 0.2405
78 OSTEOARTHRITIS 10077 0.2404
79 ARTERIOSCLEROSIS CORONARY ARTERY 1531 0.2348
80 GASTROINTESTINAL HAEMORRHAGE 19475 0.2347
81 INFUSION RELATED REACTION 15198 0.2331
82 BLOOD PRESSURE FLUCTUATION 5531 0.2328
83 GASTRIC HAEMORRHAGE 2631 0.2301
84 LABELLED DRUG-DRUG INTERACTION MEDICATION ERROR 2018 0.2291
85 SYNOVIAL CYST 1050 0.2291
86 MELAENA 4968 0.2282
87 SPINAL OSTEOARTHRITIS 1980 0.2272
88 PSORIATIC ARTHROPATHY 8908 0.2244
89 ANKYLOSING SPONDYLITIS 2885 0.2243
90 CREATININE RENAL CLEARANCE DECREASED 888 0.2233
91 BODY TEMPERATURE DECREASED 2184 0.2229
92 INFUSION SITE SWELLING 1353 0.2226
93 SUSPECTED SUICIDE 1041 0.2212
94 AUTOIMMUNE DISORDER 2080 0.2202
95 CORONARY ARTERY OCCLUSION 2976 0.2189
96 FOOT DEFORMITY 2394 0.2186
97 POISONING DELIBERATE 2003 0.2181
98 TRICUSPID VALVE INCOMPETENCE 1701 0.2181
99 INTERVERTEBRAL DISC DEGENERATION 1991 0.2167
100 RHEUMATOID ARTHRITIS 24169 0.2166
101 LOWER RESPIRATORY TRACT INFECTION 9686 0.2166
102 TYPE 2 DIABETES MELLITUS 7194 0.2158
103 C-REACTIVE PROTEIN INCREASED 7711 0.2148
104 ACUTE MYOCARDIAL INFARCTION 6250 0.2139
105 WALKING AID USER 1395 0.2135
106 CHRONIC KIDNEY DISEASE 16124 0.2132
107 POLYARTHRITIS 1099 0.2120
108 NAIL DISORDER 1806 0.2106
109 IRON DEFICIENCY 922 0.2100
110 BENIGN PROSTATIC HYPERPLASIA 1065 0.2082
111 TUBULOINTERSTITIAL NEPHRITIS 3833 0.2074
112 DIVERTICULUM 1471 0.2070
113 PRE-EXISTING CONDITION IMPROVED 1287 0.2066
114 MITRAL VALVE INCOMPETENCE 2283 0.2045
115 TENSION HEADACHE 866 0.2042
116 HYPERLIPIDAEMIA 2414 0.2040
117 HAEMATEMESIS 5116 0.2039
118 BLOOD CHOLESTEROL INCREASED 9275 0.2015
119 THERAPEUTIC PRODUCT EFFECT DECREASED 8766 0.2001
120 ATELECTASIS 1910 0.1995
121 JOINT EFFUSION 1362 0.1994
122 RENAL TUBULAR NECROSIS 1921 0.1979
123 CORONARY ARTERIAL STENT INSERTION 981 0.1964
124 BREATH SOUNDS ABNORMAL 956 0.1964
125 RALES 1126 0.1963
126 JOINT SWELLING 23218 0.1953
127 IRON DEFICIENCY ANAEMIA 1770 0.1952
128 INFUSION SITE ERYTHEMA 1592 0.1946
129 INFUSION SITE PAIN 2434 0.1931
130 ULCER 3034 0.1930
131 METABOLIC ACIDOSIS 6028 0.1929
132 PULMONARY FIBROSIS 3624 0.1921
133 TOXIC EPIDERMAL NECROLYSIS 2856 0.1919
134 HEPATIC CYTOLYSIS 2312 0.1917
135 BRONCHIECTASIS 1244 0.1892
136 HAEMORRHAGIC STROKE 1460 0.1882
137 HEPATIC ENZYME INCREASED 12595 0.1878
138 BACK INJURY 1992 0.1864
139 MUSCULOSKELETAL STIFFNESS 16059 0.1856
140 COAGULOPATHY 3039 0.1853
141 SPINAL COLUMN STENOSIS 876 0.1853
142 JOINT DISLOCATION 1919 0.1846
143 CARDIAC MURMUR 1581 0.1842
144 RENAL FAILURE ACUTE 7799 0.1836
145 PERIPHERAL VASCULAR DISORDER 940 0.1836
146 SLEEP APNOEA SYNDROME 3442 0.1824
147 RENAL CYST 1431 0.1821
148 ANGINA PECTORIS 5178 0.1819
149 TENDERNESS 1870 0.1815
150 SUBARACHNOID HAEMORRHAGE 1829 0.1814
151 ARTERIOSCLEROSIS 1686 0.1813
152 NIGHT SWEATS 5757 0.1812
153 ARTERIAL OCCLUSIVE DISEASE 1412 0.1811
154 MULTIPLE DRUG OVERDOSE 898 0.1807
155 RENAL FAILURE CHRONIC 1389 0.1805
156 HIATUS HERNIA 2305 0.1800
157 MYOCARDIAL ISCHAEMIA 2035 0.1796
158 SEASONAL ALLERGY 2500 0.1794
159 HIP ARTHROPLASTY 2689 0.1794
160 BLISTER 9906 0.1792
161 DRUG INTOLERANCE 16969 0.1787
162 DIABETIC NEUROPATHY 872 0.1775
163 GASTRITIS 4581 0.1765
164 COELIAC DISEASE 1709 0.1764
165 ACUTE KIDNEY INJURY 26371 0.1755
166 ABDOMINAL TENDERNESS 858 0.1750
167 HAEMATOCRIT DECREASED 3443 0.1747
168 SINUSITIS 17618 0.1737
169 HEART RATE DECREASED 6041 0.1735
170 TRANSIENT ISCHAEMIC ATTACK 5797 0.1734
171 PERIORBITAL OEDEMA 885 0.1729
172 MUSCULOSKELETAL PAIN 8988 0.1724
173 INTENTIONAL OVERDOSE 10788 0.1715
174 CARDIOMEGALY 2095 0.1711
175 SWELLING 15761 0.1710
176 ANGIOEDEMA 7433 0.1706
177 DISCOMFORT 10206 0.1706
178 SHOCK HAEMORRHAGIC 1362 0.1698
179 EAR PAIN 3256 0.1697
180 MULTIPLE ALLERGIES 1306 0.1687
181 FOOD ALLERGY 1257 0.1686
182 HYPOVOLAEMIA 968 0.1678
183 FLUSHING 16859 0.1673
184 PROTHROMBIN TIME PROLONGED 999 0.1673
185 ECCHYMOSIS 1133 0.1671
186 BLOOD UREA INCREASED 2775 0.1670
187 LARYNGITIS 1787 0.1668
188 WHEEZING 9716 0.1664
189 RECTAL HAEMORRHAGE 7072 0.1662
190 CORONARY ARTERY BYPASS 947 0.1661
191 FLANK PAIN 1533 0.1660
192 HEPATITIS ACUTE 1060 0.1659
193 KNEE ARTHROPLASTY 3409 0.1657
194 MOBILITY DECREASED 11518 0.1630
195 LOWER LIMB FRACTURE 3068 0.1628
196 ARTHRITIS 12656 0.1628
197 PRESCRIBED OVERDOSE 3108 0.1627
198 RESPIRATORY RATE INCREASED 1427 0.1624
199 DRUG TOXICITY 2213 0.1624
200 DRUG-INDUCED LIVER INJURY 4934 0.1621
201 VASCULITIS 1865 0.1621
202 GAIT INABILITY 5243 0.1605
203 STOMATITIS 9583 0.1601
204 INFLAMMATION 8084 0.1596
205 PHARYNGITIS 1960 0.1594
206 GOUT 2825 0.1593
207 NECK PAIN 8765 0.1587
208 COMPLETED SUICIDE 13164 0.1585
209 ROTATOR CUFF SYNDROME 2015 0.1584
210 BLOOD CALCIUM DECREASED 1749 0.1571
211 INTERVERTEBRAL DISC PROTRUSION 3395 0.1570
212 GASTROOESOPHAGEAL REFLUX DISEASE 12405 0.1568
213 TROPONIN INCREASED 1164 0.1563
214 FAECES DISCOLOURED 3340 0.1561
215 CONTUSION 14804 0.1560
216 ACUTE CORONARY SYNDROME 1282 0.1557
217 MULTIPLE INJURIES 976 0.1550
218 BODY HEIGHT DECREASED 1653 0.1549
219 INCREASED TENDENCY TO BRUISE 1408 0.1547
220 MUSCLE SPASTICITY 1890 0.1544
221 JOINT STIFFNESS 3997 0.1543
222 ACIDOSIS 1164 0.1540
223 NERVE COMPRESSION 1395 0.1534
224 MENISCUS INJURY 932 0.1533
225 OEDEMA 8187 0.1532
226 VITAMIN D DEFICIENCY 1474 0.1532
227 ORTHOSTATIC HYPOTENSION 2637 0.1531
228 BODY TEMPERATURE INCREASED 3069 0.1519
229 DYSPNOEA EXERTIONAL 5626 0.1519
230 SPUTUM DISCOLOURED 1417 0.1519
231 INTENTIONAL PRODUCT USE ISSUE 13174 0.1518
232 UPPER RESPIRATORY TRACT INFECTION 6896 0.1514
233 FACIAL PAIN 1329 0.1509
234 OESOPHAGITIS 1628 0.1509
235 PERIPHERAL SWELLING 22809 0.1506
236 MYOSITIS 1333 0.1506
237 RENAL INJURY 4447 0.1501
238 MACULAR DEGENERATION 1764 0.1500
239 RHINITIS 1187 0.1492
240 LEFT VENTRICULAR DYSFUNCTION 980 0.1489
241 TOXICITY TO VARIOUS AGENTS 24649 0.1488
242 ATRIAL FLUTTER 1174 0.1485
243 HAEMATURIA 5017 0.1482
244 DRUG HYPERSENSITIVITY 28406 0.1482
245 CARPAL TUNNEL SYNDROME 2051 0.1480
246 POOR VENOUS ACCESS 1507 0.1479
247 OBSTRUCTIVE AIRWAYS DISORDER 1628 0.1478
248 EAR INFECTION 3872 0.1478
249 LYMPHOEDEMA 1004 0.1475
250 HEART RATE IRREGULAR 3300 0.1471
251 JOINT INJURY 3104 0.1471
252 MAJOR DEPRESSION 1061 0.1467
253 HEPATIC STEATOSIS 2695 0.1467
254 MYOCARDIAL INFARCTION 25386 0.1463
255 MUSCULOSKELETAL CHEST PAIN 2233 0.1461
256 ABDOMINAL DISCOMFORT 24100 0.1461
257 SPINAL PAIN 1687 0.1460
258 ELECTROCARDIOGRAM ABNORMAL 1135 0.1458
259 INJURY 10136 0.1454
260 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 6796 0.1448
261 OSTEOPENIA 2171 0.1442
262 CHOLELITHIASIS 4667 0.1442
263 IMMUNODEFICIENCY 2083 0.1433
264 TOOTH ABSCESS 1444 0.1432
265 CARDIOVASCULAR DISORDER 3607 0.1429
266 TOOTH INFECTION 1857 0.1426
267 HYPERKALAEMIA 4897 0.1422
268 VENTRICULAR EXTRASYSTOLES 1459 0.1421
269 OSTEOPOROSIS 5769 0.1419
270 WEIGHT FLUCTUATION 1459 0.1419
271 SINUS BRADYCARDIA 1355 0.1418
272 HAEMATOMA 3639 0.1418
273 OXYGEN SATURATION DECREASED 7800 0.1416
274 ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS 1080 0.1414
275 INTERNATIONAL NORMALISED RATIO INCREASED 3995 0.1406
276 CHEST PAIN 25726 0.1405
277 INFUSION SITE EXTRAVASATION 862 0.1404
278 VENTRICULAR FIBRILLATION 1542 0.1403
279 LEUKOCYTOSIS 2501 0.1401
280 SINUS CONGESTION 1870 0.1400
281 SCOLIOSIS 858 0.1400
282 SKIN LACERATION 1491 0.1399
283 GROIN PAIN 1216 0.1397
284 VENTRICULAR TACHYCARDIA 2281 0.1394
285 LUPUS-LIKE SYNDROME 1240 0.1393
286 MUSCULOSKELETAL DISCOMFORT 2361 0.1391
287 DYSPEPSIA 13458 0.1390
288 HAEMORRHAGE INTRACRANIAL 2058 0.1390
289 RENAL FAILURE 18318 0.1388
290 OEDEMA PERIPHERAL 16744 0.1387
291 COLITIS ISCHAEMIC 915 0.1379
292 TASTE DISORDER 2720 0.1375
293 LIVER FUNCTION TEST INCREASED 2891 0.1374
294 BACK DISORDER 2210 0.1371
295 CARDIAC FAILURE CONGESTIVE 10948 0.1368
296 SUBDURAL HAEMATOMA 1939 0.1368
297 SLEEP DISORDER 9435 0.1366
298 GENERAL PHYSICAL HEALTH DETERIORATION 15486 0.1366
299 RESPIRATORY TRACT INFECTION 3497 0.1365
300 SPINAL DISORDER 1277 0.1363
301 HEMIPARESIS 2292 0.1362
302 GALLBLADDER DISORDER 2397 0.1356
303 POSTOPERATIVE WOUND INFECTION 901 0.1354
304 MUSCLE STRAIN 1154 0.1354
305 HYPERTENSION 28290 0.1352
306 PULMONARY CONGESTION 1765 0.1351
307 ORAL CANDIDIASIS 1735 0.1351
308 POST-TRAUMATIC STRESS DISORDER 894 0.1349
309 PRODUCT ADMINISTRATION INTERRUPTED 1021 0.1349
310 FEELING HOT 8162 0.1348
311 SENSORY LOSS 1073 0.1347
312 PULMONARY MASS 1975 0.1346
313 CARDIOGENIC SHOCK 1895 0.1345
314 LIGAMENT SPRAIN 1309 0.1344
315 STEVENS-JOHNSON SYNDROME 2951 0.1342
316 NEURALGIA 3210 0.1341
317 HAEMOPTYSIS 3698 0.1340
318 HEPATOTOXICITY 2923 0.1336
319 BLOOD ALBUMIN DECREASED 1042 0.1335
320 HAEMATOCHEZIA 7253 0.1334
321 GASTROINTESTINAL DISORDER 11628 0.1333
322 BRONCHITIS 9785 0.1333
323 HEMIPLEGIA 1096 0.1329
324 POLYP 858 0.1327
325 BLOOD URINE PRESENT 2495 0.1327
326 LIP SWELLING 4349 0.1326
327 NEPHROPATHY 1226 0.1324
328 HAEMORRHOIDS 2553 0.1323
329 DELIRIUM 4515 0.1323
330 ECONOMIC PROBLEM 2008 0.1321
331 TENDONITIS 2027 0.1321
332 NOCTURIA 1578 0.1320
333 RIB FRACTURE 2673 0.1319
334 BLOOD PRESSURE INCREASED 19939 0.1319
335 CYSTITIS 4159 0.1319
336 PRODUCTIVE COUGH 6153 0.1317
337 ACUTE RESPIRATORY FAILURE 2478 0.1312
338 FULL BLOOD COUNT ABNORMAL 1362 0.1309
339 INTERNAL HAEMORRHAGE 1478 0.1308
340 ARTHRALGIA 53313 0.1304
341 URINE OUTPUT DECREASED 1127 0.1303
342 MICTURITION URGENCY 1455 0.1301
343 ATRIAL FIBRILLATION 12496 0.1298
344 PLATELET COUNT INCREASED 1673 0.1297
345 ISCHAEMIC STROKE 2286 0.1296
346 VITAMIN D DECREASED 1095 0.1295
347 BLOOD CREATININE INCREASED 8350 0.1294
348 DIVERTICULITIS 3519 0.1290
349 HAEMOGLOBIN DECREASED 13089 0.1289
350 CELLULITIS 6416 0.1289
351 EMPHYSEMA 1285 0.1287
352 MUSCULAR WEAKNESS 14422 0.1286
353 RHABDOMYOLYSIS 5282 0.1286
354 THROAT IRRITATION 5669 0.1285
355 UROSEPSIS 1168 0.1284
356 CONFUSIONAL STATE 20510 0.1284
357 HYPOKALAEMIA 5812 0.1283
358 DEEP VEIN THROMBOSIS 8271 0.1283
359 BASAL CELL CARCINOMA 1972 0.1280
360 BACK PAIN 29345 0.1279
361 BLOOD IRON DECREASED 1488 0.1279
362 DRY MOUTH 10220 0.1279
363 BLOOD POTASSIUM INCREASED 2042 0.1275
364 SINUS TACHYCARDIA 1781 0.1274
365 NASOPHARYNGITIS 23168 0.1271
366 SKIN ULCER 3235 0.1270
367 UPPER-AIRWAY COUGH SYNDROME 1025 0.1268
368 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 6519 0.1267
369 HYPOAESTHESIA 18725 0.1266
370 SUICIDE ATTEMPT 7586 0.1265
371 SUPRAVENTRICULAR TACHYCARDIA 1189 0.1259
372 DEPRESSED LEVEL OF CONSCIOUSNESS 4904 0.1259
373 ALANINE AMINOTRANSFERASE INCREASED 7621 0.1257
374 LOCALISED INFECTION 3002 0.1257
375 ABDOMINAL PAIN UPPER 25471 0.1256
376 TOOTHACHE 2243 0.1256
377 HEPATITIS 3169 0.1255
378 ANAPHYLACTIC REACTION 6794 0.1253
379 STENT PLACEMENT 996 0.1252
380 PRESCRIBED UNDERDOSE 2463 0.1251
381 ANURIA 1068 0.1250
382 BLOOD MAGNESIUM DECREASED 1062 0.1246
383 EPISTAXIS 9210 0.1245
384 ARTHROPOD BITE 902 0.1243
385 LUNG DISORDER 6005 0.1243
386 FOOT FRACTURE 2329 0.1241
387 SWOLLEN TONGUE 3817 0.1237
388 PAIN IN EXTREMITY 36016 0.1237
389 HYPOTHERMIA 1237 0.1236
390 GINGIVAL PAIN 971 0.1235
391 BLOOD ALKALINE PHOSPHATASE INCREASED 3033 0.1235
392 MOUTH ULCERATION 2563 0.1235
393 DRUG INTERACTION 19323 0.1234
394 DIZZINESS POSTURAL 1169 0.1233
395 HYPOXIA 4266 0.1232
396 MIGRAINE 11538 0.1232
397 HYPOMAGNESAEMIA 1684 0.1230
398 GASTROENTERITIS 1766 0.1228
399 CHOLECYSTITIS 1433 0.1222
400 NEPHROLITHIASIS 5511 0.1221
401 RED BLOOD CELL COUNT DECREASED 3449 0.1221
402 PARAESTHESIA ORAL 1727 0.1218
403 ROAD TRAFFIC ACCIDENT 5028 0.1217
404 PRESYNCOPE 2906 0.1217
405 TONGUE DISORDER 875 0.1217
406 BONE DISORDER 2206 0.1216
407 LIVER DISORDER 5318 0.1216
408 LUNG INFILTRATION 1069 0.1216
409 SINUS DISORDER 2377 0.1214
410 HYPOTENSION 23932 0.1211
411 HYPOPHOSPHATAEMIA 878 0.1211
412 POST PROCEDURAL HAEMORRHAGE 1393 0.1208
413 ILL-DEFINED DISORDER 7227 0.1205
414 HYPERCALCAEMIA 1466 0.1204
415 LIVER FUNCTION TEST ABNORMAL 3475 0.1203
416 AORTIC ANEURYSM 909 0.1203
417 PHOTOPHOBIA 2213 0.1201
418 MENTAL STATUS CHANGES 3291 0.1200
419 BLOOD SODIUM DECREASED 2225 0.1199
420 CEREBRAL HAEMORRHAGE 4229 0.1198
421 HYPONATRAEMIA 6646 0.1198
422 DYSSTASIA 3463 0.1198
423 COORDINATION ABNORMAL 1659 0.1197
424 ASPARTATE AMINOTRANSFERASE INCREASED 6269 0.1196
425 NODULE 1539 0.1195
426 INFECTION 16995 0.1195
427 CONCUSSION 911 0.1192
428 MYOPATHY 1019 0.1192
429 GLOMERULAR FILTRATION RATE DECREASED 1424 0.1191
430 CYST 1461 0.1191
431 TINNITUS 5399 0.1189
432 UNRESPONSIVE TO STIMULI 3016 0.1188
433 GASTROINTESTINAL PAIN 1282 0.1186
434 IMPAIRED GASTRIC EMPTYING 1491 0.1185
435 ANAEMIA 22232 0.1180
436 ADRENAL INSUFFICIENCY 1392 0.1178
437 PETECHIAE 1210 0.1178
438 RESTLESS LEGS SYNDROME 2117 0.1178
439 HYPERSENSITIVITY 21541 0.1178
440 ERYTHEMA MULTIFORME 1083 0.1177
441 RESPIRATORY TRACT CONGESTION 1841 0.1173
442 LIMB INJURY 3130 0.1171
443 NEUTROPHIL COUNT INCREASED 1186 0.1169
444 NERVE INJURY 1286 0.1168
445 SPINAL COMPRESSION FRACTURE 968 0.1168
446 PERIPHERAL COLDNESS 1588 0.1168
447 GASTROENTERITIS VIRAL 2086 0.1167
448 BRADYCARDIA 6114 0.1166
449 LYMPHOCYTE COUNT DECREASED 2035 0.1166
450 HEART RATE INCREASED 11384 0.1165
451 TOOTH FRACTURE 1267 0.1165
452 WHITE BLOOD CELL COUNT INCREASED 4416 0.1162
453 HEPATIC CIRRHOSIS 2139 0.1160
454 APHTHOUS ULCER 878 0.1159
455 POOR QUALITY SLEEP 2445 0.1158
456 PURPURA 1010 0.1157
457 ATRIOVENTRICULAR BLOCK 885 0.1156
458 FACE OEDEMA 1932 0.1155
459 TREATMENT FAILURE 9356 0.1155
460 FALL 37876 0.1154
461 PYELONEPHRITIS 979 0.1152
462 URINARY TRACT INFECTION 19335 0.1152
463 CIRCULATORY COLLAPSE 1939 0.1149
464 PULMONARY HYPERTENSION 2369 0.1148
465 CLOSTRIDIUM DIFFICILE COLITIS 1203 0.1148
466 PARAESTHESIA 17860 0.1148
467 TOOTH DISORDER 2529 0.1147
468 PAIN 69548 0.1145
469 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 7993 0.1145
470 GENERALISED OEDEMA 1391 0.1145
471 RESPIRATORY DEPRESSION 1385 0.1144
472 DIPLOPIA 2932 0.1144
473 PLEURAL EFFUSION 6869 0.1143
474 TACHYPNOEA 1527 0.1142
475 CEREBROVASCULAR ACCIDENT 19077 0.1137
476 LIMB DISCOMFORT 3471 0.1136
477 TACHYCARDIA 9939 0.1134
478 HEPATIC ENCEPHALOPATHY 1045 0.1133
479 DYSURIA 4118 0.1132
480 GAIT DISTURBANCE 21448 0.1132
481 CATARACT 6627 0.1132
482 ABDOMINAL PAIN 25953 0.1131
483 PANCREATITIS ACUTE 2490 0.1131
484 COVID-19 PNEUMONIA 1326 0.1130
485 RASH MACULO-PAPULAR 2470 0.1130
486 HEPATIC FAILURE 3363 0.1128
487 DECUBITUS ULCER 906 0.1127
488 HEPATOMEGALY 1098 0.1126
489 ASPIRATION 1203 0.1125
490 BALANCE DISORDER 9609 0.1125
491 BLADDER DISORDER 1104 0.1124
492 HYPOKINESIA 1609 0.1122
493 EYELID OEDEMA 1296 0.1122
494 SYNCOPE 11073 0.1121
495 AMNESIA 7225 0.1121
496 CONSTIPATION 23896 0.1119
497 WRIST FRACTURE 1323 0.1118
498 PNEUMONIA 35647 0.1118
499 DERMATITIS CONTACT 1252 0.1117
500 PULMONARY OEDEMA 4939 0.1117
501 BLOOD POTASSIUM DECREASED 3315 0.1116
502 EJECTION FRACTION DECREASED 1714 0.1116
503 DRUG ERUPTION 1941 0.1115
504 POLYURIA 901 0.1114
505 RESPIRATORY DISORDER 3297 0.1114
506 SKIN INFECTION 1226 0.1113
507 BLOOD CALCIUM INCREASED 964 0.1112
508 CHROMATURIA 2479 0.1112
509 DENTAL CARIES 1212 0.1111
510 URTICARIA 18244 0.1111
511 PULMONARY EMBOLISM 10462 0.1110
512 BRAIN OEDEMA 1383 0.1110
513 MOTOR DYSFUNCTION 1108 0.1110
514 DYSARTHRIA 4112 0.1107
515 LACERATION 1042 0.1107
516 OSTEOMYELITIS 1975 0.1106
517 BLOOD PRESSURE DECREASED 7238 0.1106
518 CARDIO-RESPIRATORY ARREST 4590 0.1105
519 GASTRIC DISORDER 3795 0.1104
520 URINARY INCONTINENCE 3220 0.1102
521 THERAPY NON-RESPONDER 4841 0.1100
522 HYPERHIDROSIS 13999 0.1100
523 ELECTROLYTE IMBALANCE 1248 0.1100
524 HYPERAESTHESIA 895 0.1096
525 OROPHARYNGEAL PAIN 10014 0.1096
526 CHEST DISCOMFORT 11023 0.1095
527 MATERNAL EXPOSURE DURING PREGNANCY 9524 0.1094
528 EYE INFECTION 1211 0.1094
529 POST PROCEDURAL INFECTION 876 0.1094
530 ASTHENIA 40570 0.1093
531 ANHEDONIA 2855 0.1092
532 CARDIOMYOPATHY 1594 0.1091
533 NASAL CONGESTION 6303 0.1091
534 HAEMODIALYSIS 914 0.1091
535 KIDNEY INFECTION 2109 0.1089
536 DEHYDRATION 14340 0.1089
537 ORAL DISCOMFORT 1496 0.1089
538 RHINORRHOEA 6923 0.1089
539 DYSPNOEA 60714 0.1088
540 COUGH 30014 0.1087
541 ANKLE FRACTURE 1663 0.1087
542 INCONTINENCE 1135 0.1086
543 WEIGHT DECREASED 29895 0.1086
544 SMALL INTESTINAL OBSTRUCTION 1312 0.1083
545 SPLENOMEGALY 1251 0.1083
546 PHARYNGEAL SWELLING 1023 0.1083
547 COMA 5085 0.1081
548 CONDITION AGGRAVATED 32170 0.1080
549 HEAD DISCOMFORT 1876 0.1079
550 SKIN LESION 2899 0.1079
551 JAUNDICE 2873 0.1079
552 PYREXIA 36704 0.1074
553 PERICARDIAL EFFUSION 2439 0.1074
554 POST PROCEDURAL COMPLICATION 2034 0.1071
555 WEIGHT INCREASED 23458 0.1067
556 EOSINOPHIL COUNT INCREASED 875 0.1067
557 DECREASED ACTIVITY 1127 0.1066
558 FATIGUE 81669 0.1065
559 TENDON RUPTURE 1301 0.1065
560 SWELLING FACE 6825 0.1064
561 POISONING 1323 0.1062
562 SEROTONIN SYNDROME 2004 0.1062
563 VOMITING 49058 0.1060
564 MIDDLE INSOMNIA 1945 0.1060
565 GINGIVAL BLEEDING 1430 0.1060
566 STRESS 7507 0.1058
567 PALLOR 2843 0.1056
568 TRANSAMINASES INCREASED 2315 0.1056
569 BLOOD PRESSURE ABNORMAL 2064 0.1056
570 HOT FLUSH 7852 0.1056
571 ORAL PAIN 2339 0.1055
572 PAIN IN JAW 2951 0.1055
573 FLUID RETENTION 5277 0.1052
574 MUSCLE SPASMS 19033 0.1051
575 SECRETION DISCHARGE 1281 0.1051
576 LACTIC ACIDOSIS 3324 0.1050
577 DIZZINESS 51531 0.1049
578 MUSCLE TWITCHING 2391 0.1048
579 FEELING COLD 2883 0.1047
580 MULTI-ORGAN FAILURE 1812 0.1047
581 ANAL INCONTINENCE 919 0.1046
582 SHOCK 2353 0.1045
583 MEDICATION ERROR 5723 0.1045
584 ASTHMA 11549 0.1044
585 MASS 1441 0.1042
586 INSOMNIA 27424 0.1042
587 APPENDICITIS 955 0.1041
588 BLOOD TRIGLYCERIDES INCREASED 1821 0.1041
589 HERPES ZOSTER 5909 0.1040
590 EYE PAIN 5666 0.1040
591 OROPHARYNGEAL DISCOMFORT 914 0.1037
592 RASH PRURITIC 5501 0.1033
593 INTENTIONAL PRODUCT MISUSE 8840 0.1031
594 DRUG LEVEL INCREASED 1686 0.1031
595 URINARY RETENTION 3382 0.1030
596 HYPOGLYCAEMIA 4931 0.1029
597 CHILLS 11917 0.1028
598 STAPHYLOCOCCAL INFECTION 3355 0.1027
599 BLOOD CREATINE PHOSPHOKINASE INCREASED 2954 0.1024
600 GAMMA-GLUTAMYLTRANSFERASE INCREASED 2239 0.1022
601 BLOOD TEST ABNORMAL 1416 0.1022
602 DEPRESSION 23043 0.1022
603 DECREASED APPETITE 23350 0.1022
604 POLLAKIURIA 4196 0.1021
605 COGNITIVE DISORDER 4683 0.1020
606 FULL BLOOD COUNT DECREASED 2029 0.1020
607 CHOLESTASIS 1919 0.1018
608 COLD SWEAT 1770 0.1016
609 APHASIA 3037 0.1016
610 EAR DISCOMFORT 1025 0.1014
611 SCAR 1715 0.1013
612 RENAL PAIN 1056 0.1013
613 EATING DISORDER 2134 0.1012
614 INITIAL INSOMNIA 1018 0.1012
615 LETHARGY 5734 0.1010
616 MYALGIA 16935 0.1010
617 HYPOPHAGIA 2519 0.1006
618 SOMNOLENCE 19953 0.1006
619 MUSCULOSKELETAL DISORDER 1899 0.1006
620 MALNUTRITION 1102 0.1005
621 VIRAL INFECTION 3291 0.1003
622 HYPOCALCAEMIA 1868 0.1003
623 BLOOD BILIRUBIN INCREASED 2678 0.1002
624 HEADACHE 61836 0.1001
625 ATAXIA 1177 0.1001
626 CANDIDA INFECTION 1645 0.0999
627 ANOREXIA 1287 0.0998
628 HERNIA 1896 0.0998
629 OCULAR DISCOMFORT 1069 0.0997
630 SEDATION 2566 0.0997
631 RENAL IMPAIRMENT 8232 0.0997
632 HEAD INJURY 3105 0.0997
633 PHARYNGEAL OEDEMA 1531 0.0995
634 HYPOAESTHESIA ORAL 1476 0.0993
635 MUSCLE TIGHTNESS 1585 0.0993
636 PRODUCT USE IN UNAPPROVED INDICATION 23926 0.0992
637 PALPITATIONS 11442 0.0991
638 ENCEPHALOPATHY 2393 0.0990
639 DYSPHONIA 5703 0.0989
640 DISORIENTATION 3874 0.0988
641 PNEUMONIA ASPIRATION 2428 0.0987
642 DYSPHAGIA 9217 0.0987
643 NEUROPATHY PERIPHERAL 9182 0.0984
644 THROMBOSIS 7835 0.0984
645 THROAT TIGHTNESS 2618 0.0982
646 BLOOD LACTATE DEHYDROGENASE INCREASED 1543 0.0980
647 PRURITUS 36538 0.0980
648 SEPTIC SHOCK 4178 0.0980
649 HALLUCINATION, VISUAL 2025 0.0978
650 ABDOMINAL DISTENSION 10033 0.0978
651 SEPSIS 10768 0.0978
652 CYTOKINE RELEASE SYNDROME 1838 0.0977
653 MUSCLE ATROPHY 1212 0.0977
654 PRURITUS GENERALISED 2114 0.0976
655 TEMPERATURE INTOLERANCE 982 0.0974
656 UVEITIS 1298 0.0974
657 INFLUENZA 10734 0.0973
658 BURNING SENSATION 6725 0.0972
659 DIABETES MELLITUS INADEQUATE CONTROL 1698 0.0972
660 PHARYNGITIS STREPTOCOCCAL 1038 0.0971
661 BACTERIAL INFECTION 1777 0.0970
662 HYPERSOMNIA 2738 0.0969
663 RASH 41466 0.0969
664 CARDIAC ARREST 7915 0.0968
665 MOVEMENT DISORDER 3079 0.0967
666 RASH ERYTHEMATOUS 4468 0.0966
667 IMPAIRED WORK ABILITY 2043 0.0965
668 RESPIRATORY DISTRESS 2624 0.0963
669 DIARRHOEA 61088 0.0962
670 MEMORY IMPAIRMENT 13038 0.0961
671 ACUTE RESPIRATORY DISTRESS SYNDROME 1676 0.0960
672 HYPERGLYCAEMIA 3439 0.0959
673 ALOPECIA 18625 0.0959
674 NAUSEA 74578 0.0958
675 DIARRHOEA HAEMORRHAGIC 885 0.0957
676 THERAPEUTIC RESPONSE UNEXPECTED 4245 0.0956
677 FREQUENT BOWEL MOVEMENTS 2536 0.0955
678 HALLUCINATION 7060 0.0954
679 LYMPHADENOPATHY 3335 0.0954
680 VERTIGO 5740 0.0954
681 PHOTOSENSITIVITY REACTION 1546 0.0952
682 INSURANCE ISSUE 1393 0.0950
683 COLITIS 3532 0.0950
684 RESPIRATORY FAILURE 6840 0.0950
685 DIABETES MELLITUS 7174 0.0949
686 ANXIETY 26695 0.0948
687 SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION 1513 0.0948
688 DRY THROAT 949 0.0947
689 MULTIPLE ORGAN DYSFUNCTION SYNDROME 2608 0.0947
690 SKIN HAEMORRHAGE 1345 0.0944
691 FEBRILE NEUTROPENIA 6168 0.0944
692 HAEMORRHAGE 9734 0.0944
693 RENAL DISORDER 4346 0.0943
694 CHOLECYSTECTOMY 1057 0.0943
695 DERMATITIS ALLERGIC 1159 0.0942
696 UPPER LIMB FRACTURE 1861 0.0942
697 LOSS OF CONSCIOUSNESS 11906 0.0941
698 ORAL HERPES 1803 0.0940
699 CHOKING 1796 0.0937
700 EOSINOPHILIA 1614 0.0936
701 BACTERAEMIA 1087 0.0936
702 CEREBRAL INFARCTION 2253 0.0933
703 EYE HAEMORRHAGE 1224 0.0927
704 CONJUNCTIVITIS 1681 0.0927
705 HYPOTHYROIDISM 2913 0.0927
706 FLATULENCE 5149 0.0922
707 PNEUMOTHORAX 1441 0.0921
708 GLAUCOMA 1750 0.0920
709 SNEEZING 2024 0.0917
710 RETCHING 1923 0.0916
711 ACTIVITIES OF DAILY LIVING IMPAIRED 1815 0.0915
712 EYE SWELLING 3333 0.0914
713 EXPOSURE DURING PREGNANCY 5603 0.0913
714 PRODUCT USE ISSUE 16840 0.0913
715 ADVERSE REACTION 1195 0.0913
716 ALTERED STATE OF CONSCIOUSNESS 1939 0.0912
717 BONE PAIN 5264 0.0910
718 SCAB 1017 0.0909
719 SCRATCH 928 0.0908
720 NEPHROPATHY TOXIC 998 0.0908
721 QUALITY OF LIFE DECREASED 1196 0.0902
722 THYROID DISORDER 1372 0.0902
723 ARRHYTHMIA 4231 0.0901
724 KNEE OPERATION 864 0.0901
725 ANAPHYLACTIC SHOCK 2279 0.0901
726 ABDOMINAL PAIN LOWER 2255 0.0901
727 FEELING JITTERY 1696 0.0900
728 RASH PAPULAR 1994 0.0900
729 SPINAL FRACTURE 1769 0.0899
730 SENSORY DISTURBANCE 1431 0.0899
731 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 1489 0.0898
732 ABSCESS 1411 0.0897
733 NIGHTMARE 3071 0.0895
734 BEDRIDDEN 1160 0.0895
735 LOCAL SWELLING 1563 0.0895
736 BRONCHOSPASM 1260 0.0892
737 TRANSFUSION 925 0.0891
738 ASCITES 2587 0.0891
739 MALAISE 38606 0.0890
740 THROMBOCYTOPENIA 9793 0.0890
741 DISABILITY 1736 0.0889
742 EPILEPSY 2676 0.0888
743 SKIN DISCOLOURATION 4027 0.0888
744 RESPIRATORY ARREST 2428 0.0884
745 HIP FRACTURE 2790 0.0881
746 CARDIAC FAILURE 6975 0.0880
747 AGRANULOCYTOSIS 1603 0.0879
748 IMPAIRED QUALITY OF LIFE 1246 0.0877
749 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 881 0.0877
750 DISSEMINATED INTRAVASCULAR COAGULATION 1220 0.0875
751 ACCIDENTAL OVERDOSE 3157 0.0875
752 LABORATORY TEST ABNORMAL 2546 0.0875
753 INFLUENZA LIKE ILLNESS 7135 0.0875
754 PULMONARY THROMBOSIS 943 0.0875
755 ABASIA 2162 0.0874
756 RASH MACULAR 3001 0.0873
757 RESTLESSNESS 3157 0.0873
758 EYE DISORDER 2803 0.0867
759 COVID-19 15119 0.0866
760 DRUG EFFECT LESS THAN EXPECTED 1202 0.0864
761 APHONIA 1189 0.0864
762 HYPERBILIRUBINAEMIA 878 0.0863
763 MYOCLONUS 1016 0.0863
764 HYPERTENSIVE CRISIS 950 0.0862
765 FEAR 2301 0.0860
766 CYANOSIS 1336 0.0859
767 PROTEINURIA 1596 0.0858
768 PANCREATITIS 4478 0.0857
769 CARDIAC DISORDER 7935 0.0856
770 DISTURBANCE IN ATTENTION 4556 0.0854
771 PROSTATIC SPECIFIC ANTIGEN INCREASED 1160 0.0848
772 TREMOR 13917 0.0848
773 PREMATURE DELIVERY 1339 0.0848
774 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 2136 0.0847
775 PRODUCT PRESCRIBING ERROR 1973 0.0844
776 HAIR COLOUR CHANGES 1048 0.0844
777 SPEECH DISORDER 4361 0.0843
778 DRUG EFFECT INCOMPLETE 3066 0.0843
779 ERUCTATION 1582 0.0843
780 DEAFNESS 2177 0.0842
781 WHITE BLOOD CELL COUNT DECREASED 9002 0.0841
782 AGEUSIA 2068 0.0838
783 DYSGEUSIA 6169 0.0837
784 VISION BLURRED 11264 0.0836
785 ERYTHEMA 16920 0.0835
786 ILEUS 1014 0.0835
787 SARS-COV-2 TEST POSITIVE 1097 0.0832
788 PNEUMONITIS 2220 0.0832
789 CLOSTRIDIUM DIFFICILE INFECTION 1779 0.0832
790 FEELING ABNORMAL 19744 0.0832
791 MALIGNANT MELANOMA 1101 0.0832
792 FEEDING DISORDER 1627 0.0827
793 PANCYTOPENIA 4529 0.0824
794 PLATELET COUNT DECREASED 8633 0.0821
795 SUDDEN DEATH 865 0.0820
796 INTESTINAL PERFORATION 909 0.0820
797 FEMUR FRACTURE 2512 0.0820
798 FUNGAL INFECTION 2690 0.0819
799 DRY EYE 3912 0.0818
800 DEPRESSED MOOD 4232 0.0815
801 HEPATOCELLULAR INJURY 1141 0.0813
802 MYOCARDITIS 908 0.0813
803 IMMUNE SYSTEM DISORDER 1053 0.0811
804 LACRIMATION INCREASED 2389 0.0810
805 NERVOUSNESS 4184 0.0807
806 RASH GENERALISED 2092 0.0807
807 OVERDOSE 17222 0.0806
808 BRAIN FOG 1157 0.0804
809 BIPOLAR DISORDER 868 0.0803
810 BLINDNESS UNILATERAL 1114 0.0802
811 MUSCLE RIGIDITY 945 0.0801
812 ANOSMIA 1145 0.0800
813 PARANOIA 1367 0.0800
814 DELUSION 1222 0.0799
815 AGITATION 5807 0.0799
816 INTENTIONAL SELF-INJURY 1587 0.0797
817 SKIN DISORDER 2591 0.0789
818 ELECTROCARDIOGRAM QT PROLONGED 2798 0.0788
819 PRODUCT ADMINISTRATION ERROR 1546 0.0785
820 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 4315 0.0784
821 IMPAIRED DRIVING ABILITY 880 0.0784
822 SPINAL OPERATION 936 0.0784
823 HAIR TEXTURE ABNORMAL 1039 0.0780
824 POLYNEUROPATHY 912 0.0777
825 THIRST 1361 0.0774
826 LEUKOPENIA 3792 0.0770
827 PRODUCT TASTE ABNORMAL 1021 0.0769
828 PREMATURE BABY 2290 0.0769
829 DEMENTIA 2111 0.0768
830 MYDRIASIS 969 0.0766
831 PSORIASIS 9882 0.0766
832 INTENTIONAL DRUG MISUSE 1597 0.0763
833 FLUID OVERLOAD 1110 0.0762
834 BLINDNESS 3011 0.0749
835 ILLNESS 7426 0.0749
836 ACCIDENT 879 0.0748
837 MUCOSAL INFLAMMATION 1923 0.0748
838 TOOTH EXTRACTION 917 0.0746
839 PARALYSIS 1055 0.0744
840 VISUAL IMPAIRMENT 9009 0.0742
841 PROCEDURAL PAIN 2025 0.0742
842 LYMPHOPENIA 1025 0.0738
843 LUNG INFECTION 1147 0.0738
844 DYSKINESIA 2951 0.0737
845 ERECTILE DYSFUNCTION 1861 0.0732
846 DRUG INEFFECTIVE 95074 0.0732
847 BLOOD COUNT ABNORMAL 1106 0.0729
848 NEUTROPHIL COUNT DECREASED 2910 0.0728
849 PANIC ATTACK 2616 0.0727
850 OFF LABEL USE 61585 0.0719
851 PLASMA CELL MYELOMA 2769 0.0718
852 THERAPEUTIC RESPONSE SHORTENED 2249 0.0716
853 METASTASES TO BONE 1150 0.0712
854 INTENTIONAL DOSE OMISSION 1915 0.0710
855 ABNORMAL DREAMS 1946 0.0709
856 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 12352 0.0708
857 THINKING ABNORMAL 1308 0.0707
858 EXPIRED PRODUCT ADMINISTERED 2316 0.0707
859 INTERSTITIAL LUNG DISEASE 3341 0.0701
860 DEVICE RELATED INFECTION 1065 0.0699
861 MULTIPLE FRACTURES 1143 0.0699
862 DERMATITIS 1428 0.0698
863 DIALYSIS 980 0.0698
864 TREATMENT NONCOMPLIANCE 3737 0.0697
865 MENTAL DISORDER 2996 0.0696
866 CONVULSION 3933 0.0687
867 APATHY 984 0.0686
868 SKIN REACTION 952 0.0686
869 HYPERTHYROIDISM 976 0.0684
870 PELVIC PAIN 1224 0.0682
871 VISUAL ACUITY REDUCED 2250 0.0681
872 CRYING 2443 0.0679
873 INTESTINAL OBSTRUCTION 2498 0.0676
874 DISEASE RECURRENCE 3178 0.0675
875 HUNGER 890 0.0671
876 PREGNANCY 1336 0.0669
877 COLITIS ULCERATIVE 2935 0.0667
878 ADVERSE DRUG REACTION 5878 0.0666
879 THERAPEUTIC RESPONSE DECREASED 3960 0.0665
880 MENTAL IMPAIRMENT 1593 0.0665
881 HALLUCINATION, AUDITORY 1044 0.0665
882 HEPATIC FUNCTION ABNORMAL 2423 0.0662
883 PRODUCT USE COMPLAINT 1013 0.0662
884 SURGERY 3780 0.0661
885 HYPOACUSIS 2801 0.0661
886 EYE PRURITUS 2139 0.0657
887 SKIN CANCER 1398 0.0657
888 DRUG EFFECT DECREASED 3537 0.0656
889 FRACTURE 1224 0.0655
890 BLOOD GLUCOSE DECREASED 3094 0.0650
891 SKIN FISSURES 1207 0.0648
892 LYMPHOMA 989 0.0647
893 PRODUCT DOSE OMISSION IN ERROR 1695 0.0640
894 INCREASED APPETITE 1184 0.0638
895 UNEVALUABLE EVENT 4764 0.0638
896 PSYCHOTIC DISORDER 1859 0.0638
897 PSYCHOMOTOR HYPERACTIVITY 1048 0.0637
898 BLOOD GLUCOSE INCREASED 11855 0.0635
899 SUICIDAL IDEATION 5727 0.0633
900 OCULAR HYPERAEMIA 2919 0.0633
901 GLYCOSYLATED HAEMOGLOBIN INCREASED 1569 0.0631
902 INCORRECT PRODUCT ADMINISTRATION DURATION 1260 0.0629
903 BONE DENSITY DECREASED 1965 0.0629
904 NEUTROPENIA 8380 0.0627
905 GENERALISED TONIC-CLONIC SEIZURE 1010 0.0625
906 COLON CANCER 919 0.0624
907 PERITONITIS 1273 0.0623
908 PAIN OF SKIN 1653 0.0620
909 PULMONARY ARTERIAL HYPERTENSION 887 0.0617
910 INJECTION SITE HAEMATOMA 890 0.0615
911 PRODUCT PHYSICAL ISSUE 1204 0.0612
912 DRUG ABUSE 4971 0.0602
913 INCORRECT DRUG ADMINISTRATION DURATION 1694 0.0602
914 MULTIPLE SCLEROSIS 2847 0.0600
915 THERAPY CESSATION 2994 0.0594
916 SEIZURE 6710 0.0592
917 TOOTH LOSS 1220 0.0592
918 INJECTION SITE BRUISING 4593 0.0590
919 WRONG TECHNIQUE IN DRUG USAGE PROCESS 2145 0.0590
920 NERVOUS SYSTEM DISORDER 1816 0.0588
921 METASTASES TO LIVER 1016 0.0587
922 ANGER 1954 0.0583
923 DRUG ADMINISTRATION ERROR 1787 0.0582
924 OSTEONECROSIS OF JAW 1418 0.0577
925 IRRITABILITY 3422 0.0576
926 SKIN EXFOLIATION 4720 0.0576
927 UNDERDOSE 4133 0.0573
928 ECZEMA 2777 0.0559
929 EMOTIONAL DISTRESS 6687 0.0558
930 DIABETIC KETOACIDOSIS 1319 0.0558
931 DISEASE PROGRESSION 6447 0.0554
932 BLOOD GLUCOSE ABNORMAL 1011 0.0553
933 EYE IRRITATION 3043 0.0553
934 EMOTIONAL DISORDER 1686 0.0551
935 AGGRESSION 2712 0.0548
936 MOOD ALTERED 1468 0.0547
937 MOOD SWINGS 1717 0.0545
938 PRODUCT DOSE OMISSION ISSUE 15306 0.0545
939 ADVERSE EVENT 4940 0.0543
940 ABNORMAL BEHAVIOUR 2110 0.0536
941 PRODUCT QUALITY ISSUE 7091 0.0533
942 INCORRECT DOSE ADMINISTERED 11751 0.0529
943 MULTIPLE SCLEROSIS RELAPSE 3609 0.0529
944 PHARMACEUTICAL PRODUCT COMPLAINT 1357 0.0522
945 THERAPY INTERRUPTED 3554 0.0522
946 INJECTION SITE REACTION 3479 0.0514
947 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 3616 0.0508
948 PRODUCT AVAILABILITY ISSUE 1118 0.0505
949 INJECTION SITE HAEMORRHAGE 3946 0.0504
950 PRODUCT DOSE OMISSION 3280 0.0502
951 DRUG PRESCRIBING ERROR 963 0.0501
952 OSTEONECROSIS 1630 0.0498
953 DRY SKIN 6440 0.0496
954 PRODUCT SUBSTITUTION ISSUE 2725 0.0480
955 WITHDRAWAL SYNDROME 1959 0.0470
956 VAGINAL HAEMORRHAGE 1965 0.0468
957 INJECTION SITE PRURITUS 3050 0.0464
958 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 1066 0.0462
959 BONE MARROW FAILURE 927 0.0459
960 INJECTION SITE ERYTHEMA 5566 0.0457
961 DRUG DOSE OMISSION 7555 0.0457
962 INJECTION SITE MASS 1650 0.0454
963 MENORRHAGIA 890 0.0453
964 PRODUCT PRESCRIBING ISSUE 908 0.0452
965 LUNG NEOPLASM MALIGNANT 1823 0.0447
966 SKIN BURNING SENSATION 3071 0.0437
967 NEOPLASM MALIGNANT 2871 0.0436
968 INJECTION SITE RASH 1306 0.0436
969 NEOPLASM PROGRESSION 1488 0.0430
970 MALIGNANT NEOPLASM PROGRESSION 4220 0.0420
971 INJECTION SITE SWELLING 3089 0.0413
972 EXTRA DOSE ADMINISTERED 1623 0.0412
973 ABORTION SPONTANEOUS 1635 0.0412
974 INJECTION SITE PAIN 11977 0.0400
975 INJECTION SITE URTICARIA 949 0.0396
976 HOSPITALISATION 5943 0.0395
977 DEATH 31203 0.0367
978 NEEDLE ISSUE 1031 0.0365
979 EXTRAPYRAMIDAL DISORDER 873 0.0353
980 DRUG EXPOSURE DURING PREGNANCY 1195 0.0351
981 DEVICE DISLOCATION 1448 0.0338
982 DEVICE MALFUNCTION 2186 0.0330
983 ACNE 2441 0.0325
984 DEVICE ISSUE 2766 0.0321
985 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 6343 0.0318
986 SKIN IRRITATION 1363 0.0301
987 DRUG WITHDRAWAL SYNDROME 2457 0.0281
988 DERMATITIS ATOPIC 1360 0.0276
989 BREAST CANCER 2516 0.0271
990 CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR 884 0.0267
991 DRUG DEPENDENCE 3766 0.0235
992 ACCIDENTAL EXPOSURE TO PRODUCT 2258 0.0229
993 NO ADVERSE EVENT 3846 0.0220
994 PROSTATE CANCER 1642 0.0205
995 PRODUCT STORAGE ERROR 1146 0.0134
996 DEVICE DIFFICULT TO USE 869 0.0133