Platinum-based Drug [EPC]

Platinum-based Drug [EPC] was reported 164001 times

Drugs of the Platinum-based Drug [EPC] class are most commonly taken among patients reporting these side effects:

# Drug class Count Frequency
0 DYSAESTHESIA PHARYNX 77 0.6016
1 RENAL SALT-WASTING SYNDROME 117 0.5735
2 DIFFUSE LARGE B-CELL LYMPHOMA REFRACTORY 191 0.4987
3 RADIATION OESOPHAGITIS 148 0.4983
4 TUMOUR PERFORATION 70 0.3723
5 OESOPHAGEAL FISTULA 88 0.3577
6 ANASTOMOTIC LEAK 175 0.3340
7 NON-CIRRHOTIC PORTAL HYPERTENSION 67 0.3221
8 PORTAL VENOUS GAS 78 0.3120
9 OTOTOXICITY 412 0.3112
10 DIFFUSE LARGE B-CELL LYMPHOMA RECURRENT 306 0.3009
11 MENINGITIS TUBERCULOUS 118 0.2554
12 HAIR DISORDER 1937 0.2509
13 MALIGNANT TRANSFORMATION 76 0.2508
14 GASTROINTESTINAL ANASTOMOTIC LEAK 70 0.2482
15 HAEMATOTOXICITY 1377 0.2420
16 OSTEOSARCOMA 66 0.2391
17 ANASTOMOTIC COMPLICATION 66 0.2340
18 GASTROINTESTINAL TOXICITY 648 0.2338
19 NEUTROPENIC SEPSIS 1260 0.2256
20 AORTIC THROMBOSIS 186 0.2222
21 RECALL PHENOMENON 146 0.2209
22 MYELOSUPPRESSION 1364 0.2179
23 PSYCHOLOGICAL TRAUMA 1796 0.2169
24 IMMUNE-MEDIATED HEPATIC DISORDER 71 0.2139
25 RADIATION PNEUMONITIS 314 0.2038
26 RADIATION SKIN INJURY 192 0.2034
27 TUMOUR NECROSIS 157 0.2008
28 SKIN TOXICITY 668 0.1998
29 COLORECTAL CANCER METASTATIC 178 0.1980
30 OVARIAN CANCER RECURRENT 141 0.1967
31 RECTAL PERFORATION 78 0.1931
32 PERIPHERAL SENSORY NEUROPATHY 790 0.1929
33 HAIR COLOUR CHANGES 2059 0.1921
34 VENOOCCLUSIVE LIVER DISEASE 642 0.1874
35 MUCOSAL INFLAMMATION 3528 0.1862
36 BONE MARROW TOXICITY 221 0.1829
37 FOCAL NODULAR HYPERPLASIA 78 0.1814
38 NEUTROPENIC COLITIS 221 0.1813
39 MADAROSIS 1907 0.1808
40 FEBRILE NEUTROPENIA 7999 0.1791
41 HAIR TEXTURE ABNORMAL 2065 0.1758
42 METASTASES TO PERITONEUM 288 0.1752
43 NEUTROPENIC INFECTION 130 0.1684
44 GASTROINTESTINAL PERFORATION 515 0.1673
45 LYMPHANGIOSIS CARCINOMATOSA 125 0.1603
46 TRACHEO-OESOPHAGEAL FISTULA 82 0.1592
47 NON-SMALL CELL LUNG CANCER 414 0.1587
48 METASTASES TO SKIN 107 0.1551
49 METASTASES TO MENINGES 209 0.1545
50 NODULAR REGENERATIVE HYPERPLASIA 78 0.1538
51 DERMATITIS ACNEIFORM 645 0.1533
52 PERIPHERAL MOTOR NEUROPATHY 161 0.1526
53 LARYNGOSPASM 321 0.1483
54 METASTASES TO ADRENALS 96 0.1477
55 SUPERIOR VENA CAVA SYNDROME 67 0.1447
56 REVERSIBLE POSTERIOR LEUKOENCEPHALOPATHY SYNDROME 111 0.1418
57 ARTERIOSPASM CORONARY 376 0.1417
58 HYPOMAGNESAEMIA 1292 0.1382
59 THERAPY PARTIAL RESPONDER 571 0.1361
60 NEUTROPHIL COUNT ABNORMAL 248 0.1321
61 NEUROTOXICITY 1515 0.1316
62 BONE MARROW FAILURE 2328 0.1285
63 MALIGNANT ASCITES 73 0.1272
64 CULTURE URINE POSITIVE 154 0.1248
65 ACQUIRED GENE MUTATION 107 0.1237
66 HYPERAMMONAEMIC ENCEPHALOPATHY 165 0.1235
67 ADMINISTRATION SITE EXTRAVASATION 71 0.1235
68 APLASIA 223 0.1231
69 SMALL INTESTINAL PERFORATION 159 0.1231
70 FEBRILE BONE MARROW APLASIA 356 0.1219
71 ENTEROCUTANEOUS FISTULA 80 0.1212
72 GRANULOCYTE COUNT DECREASED 90 0.1205
73 NEUTROPHIL COUNT DECREASED 3118 0.1184
74 DEVICE RELATED THROMBOSIS 71 0.1179
75 PNEUMATOSIS INTESTINALIS 223 0.1177
76 PARONYCHIA 341 0.1162
77 MALIGNANT PLEURAL EFFUSION 145 0.1155
78 NEUTROPENIA 10306 0.1155
79 METASTASES TO LUNG 898 0.1137
80 METASTASES TO PLEURA 76 0.1133
81 CARCINOEMBRYONIC ANTIGEN INCREASED 147 0.1125
82 CARDIOTOXICITY 614 0.1123
83 TUMOUR LYSIS SYNDROME 636 0.1114
84 ENTEROCOLITIS INFECTIOUS 85 0.1101
85 IMMUNE-MEDIATED ENTEROCOLITIS 111 0.1100
86 METASTASES TO LYMPH NODES 488 0.1093
87 NEOPLASM RECURRENCE 262 0.1089
88 IMMUNE-MEDIATED HEPATITIS 73 0.1088
89 PELVIC ABSCESS 93 0.1068
90 OESOPHAGITIS 889 0.1065
91 FEMALE GENITAL TRACT FISTULA 114 0.1060
92 DUODENAL PERFORATION 71 0.1060
93 METASTASES TO LIVER 1303 0.1057
94 ENTERITIS 441 0.1047
95 SMALL CELL LUNG CANCER 98 0.1043
96 CATHETER RELATED INFECTION 104 0.1027
97 RADIATION INJURY 75 0.1025
98 ORAL INTAKE REDUCED 246 0.1016
99 SUBCLAVIAN VEIN THROMBOSIS 98 0.1014
100 SUBILEUS 175 0.1006
101 VENA CAVA THROMBOSIS 133 0.1005
102 THROMBOCYTOPENIA 8033 0.1004
103 ENTEROCOLITIS 355 0.0991
104 GASTRIC PERFORATION 191 0.0989
105 POLYNEUROPATHY 777 0.0985
106 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 1642 0.0968
107 CYTOPENIA 561 0.0958
108 LARGE INTESTINE PERFORATION 504 0.0957
109 PORTAL HYPERTENSION 216 0.0955
110 SECOND PRIMARY MALIGNANCY 578 0.0954
111 IMPAIRED QUALITY OF LIFE 720 0.0952
112 ACUTE MYELOID LEUKAEMIA 1084 0.0949
113 TUMOUR HAEMORRHAGE 192 0.0945
114 LEUKOPENIA 3516 0.0945
115 SYSTEMIC INFECTION 81 0.0941
116 ARTERIAL THROMBOSIS 148 0.0930
117 HYPOALBUMINAEMIA 501 0.0919
118 VENOOCCLUSIVE DISEASE 164 0.0917
119 PALMAR ERYTHEMA 82 0.0914
120 METASTASES TO CENTRAL NERVOUS SYSTEM 764 0.0913
121 LYMPHADENOPATHY MEDIASTINAL 125 0.0912
122 BLOOD CULTURE POSITIVE 245 0.0904
123 NEPHROPATHY TOXIC 664 0.0903
124 TYPE I HYPERSENSITIVITY 178 0.0893
125 PERIPHERAL ISCHAEMIA 274 0.0865
126 ACUTE PROMYELOCYTIC LEUKAEMIA 68 0.0865
127 MALIGNANT NEOPLASM PROGRESSION 5812 0.0862
128 PERFORMANCE STATUS DECREASED 312 0.0862
129 LEUKOENCEPHALOPATHY 251 0.0856
130 POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME 543 0.0852
131 EMBOLISM VENOUS 187 0.0846
132 PANCYTOPENIA 3419 0.0838
133 LUNG ADENOCARCINOMA 181 0.0834
134 COLON CANCER METASTATIC 102 0.0825
135 ADENOCARCINOMA 141 0.0819
136 ADENOCARCINOMA OF COLON 109 0.0815
137 FANCONI SYNDROME 85 0.0809
138 BICYTOPENIA 89 0.0807
139 ILEUS 720 0.0803
140 OESOPHAGEAL STENOSIS 169 0.0800
141 MYELODYSPLASTIC SYNDROME 887 0.0799
142 HYPERTRANSAMINASAEMIA 196 0.0785
143 EMBOLISM 511 0.0785
144 METASTASIS 388 0.0784
145 RENAL TUBULAR DISORDER 184 0.0772
146 DISEASE PROGRESSION 6041 0.0772
147 BONE MARROW DEPRESSION 75 0.0768
148 ODYNOPHAGIA 321 0.0767
149 BLOOD CHLORIDE DECREASED 168 0.0767
150 ALOPECIA AREATA 92 0.0766
151 HYDRONEPHROSIS 423 0.0764
152 CHOLANGITIS 307 0.0752
153 PROCTITIS 128 0.0739
154 STRIDOR 167 0.0738
155 METASTATIC NEOPLASM 227 0.0734
156 EMBOLISM ARTERIAL 69 0.0732
157 HYPOKALAEMIA 2431 0.0730
158 PNEUMONITIS 1293 0.0729
159 PULMONARY TOXICITY 318 0.0726
160 EMPYEMA 102 0.0720
161 JUGULAR VEIN THROMBOSIS 95 0.0711
162 DYSAESTHESIA 158 0.0705
163 HAEMOLYTIC URAEMIC SYNDROME 141 0.0697
164 HYPOPHOSPHATAEMIA 347 0.0696
165 NEUROPATHY PERIPHERAL 4419 0.0695
166 PROTEINURIA 875 0.0691
167 EXTREMITY NECROSIS 90 0.0682
168 INTESTINAL PERFORATION 567 0.0681
169 GENE MUTATION 86 0.0681
170 FAILURE TO THRIVE 283 0.0667
171 URETERIC OBSTRUCTION 71 0.0667
172 GASTROINTESTINAL NECROSIS 152 0.0666
173 CLOSTRIDIUM COLITIS 70 0.0664
174 CAPILLARY LEAK SYNDROME 92 0.0663
175 HYPERAMMONAEMIA 236 0.0663
176 PERIPHERAL ARTERY THROMBOSIS 66 0.0658
177 STEM CELL TRANSPLANT 119 0.0658
178 CATHETER RELATED COMPLICATION 74 0.0657
179 METASTASES TO BONE 695 0.0657
180 PNEUMOMEDIASTINUM 73 0.0657
181 ASPERGILLUS INFECTION 261 0.0657
182 NEOPLASM PROGRESSION 1566 0.0656
183 LIVER ABSCESS 153 0.0656
184 ELECTROLYTE IMBALANCE 522 0.0652
185 VENOUS THROMBOSIS 204 0.0652
186 CACHEXIA 251 0.0651
187 INTESTINAL ISCHAEMIA 268 0.0650
188 HYPOPITUITARISM 71 0.0646
189 CYTOKINE RELEASE SYNDROME 370 0.0641
190 RENAL INFARCT 70 0.0633
191 LOBAR PNEUMONIA 116 0.0625
192 IMMUNE THROMBOCYTOPENIA 98 0.0623
193 THROMBOTIC MICROANGIOPATHY 383 0.0621
194 INTERSTITIAL LUNG DISEASE 2074 0.0617
195 SMALL INTESTINAL OBSTRUCTION 555 0.0617
196 DISSEMINATED INTRAVASCULAR COAGULATION 702 0.0616
197 DIFFUSE LARGE B-CELL LYMPHOMA 262 0.0614
198 VENOUS THROMBOSIS LIMB 104 0.0612
199 PNEUMOPERITONEUM 83 0.0612
200 METASTASES TO SPINE 137 0.0603
201 HYPOCALCAEMIA 825 0.0601
202 CYSTITIS HAEMORRHAGIC 174 0.0600
203 ACUTE ABDOMEN 73 0.0600
204 ESCHERICHIA BACTERAEMIA 87 0.0599
205 HYPOVOLAEMIA 270 0.0598
206 SEPTIC SHOCK 1833 0.0593
207 CANCER PAIN 98 0.0589
208 TROPONIN I INCREASED 68 0.0571
209 ANAEMIA 8237 0.0571
210 BLOOD PRESSURE IMMEASURABLE 71 0.0560
211 DIVERTICULAR PERFORATION 94 0.0552
212 ASCITES 1220 0.0552
213 DISEASE RECURRENCE 957 0.0548
214 WOUND DEHISCENCE 149 0.0547
215 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 397 0.0543
216 RECURRENT CANCER 137 0.0542
217 ELECTROCARDIOGRAM ST SEGMENT ELEVATION 145 0.0538
218 LEFT VENTRICULAR DYSFUNCTION 266 0.0537
219 BACTERAEMIA 423 0.0533
220 DEHYDRATION 5435 0.0533
221 EXTRAVASATION 178 0.0528
222 LUNG CONSOLIDATION 113 0.0527
223 VOCAL CORD PARALYSIS 72 0.0527
224 NEUROPATHY 89 0.0524
225 STAPHYLOCOCCUS TEST POSITIVE 89 0.0523
226 LARGE INTESTINAL OBSTRUCTION 77 0.0521
227 ATELECTASIS 405 0.0520
228 VARICES OESOPHAGEAL 120 0.0519
229 PNEUMOTHORAX 583 0.0515
230 MULTIPLE-DRUG RESISTANCE 83 0.0512
231 STOMATITIS 2156 0.0511
232 STRESS CARDIOMYOPATHY 185 0.0508
233 CEREBRAL ISCHAEMIA 221 0.0507
234 ACUTE RESPIRATORY DISTRESS SYNDROME 669 0.0506
235 HYPERBILIRUBINAEMIA 371 0.0502
236 BLOOD ALBUMIN DECREASED 304 0.0496
237 HICCUPS 292 0.0496
238 AUTOIMMUNE HAEMOLYTIC ANAEMIA 104 0.0493
239 PULMONARY HAEMORRHAGE 317 0.0493
240 PORTAL VEIN THROMBOSIS 117 0.0485
241 ACUTE LYMPHOCYTIC LEUKAEMIA 103 0.0485
242 LUNG ABSCESS 75 0.0484
243 KLEBSIELLA INFECTION 163 0.0484
244 CLOSTRIDIAL INFECTION 149 0.0483
245 SYSTEMIC CANDIDA 76 0.0481
246 BLOOD MAGNESIUM DECREASED 287 0.0481
247 ABDOMINAL ABSCESS 154 0.0481
248 ILEUS PARALYTIC 158 0.0481
249 HYPONATRAEMIA 2027 0.0475
250 SEPSIS 3956 0.0475
251 LYMPHOPENIA 471 0.0471
252 HYPERPYREXIA 117 0.0468
253 LUNG CANCER METASTATIC 106 0.0466
254 HEPATIC LESION 142 0.0465
255 PLATELET COUNT DECREASED 3507 0.0462
256 BACTERIAL SEPSIS 112 0.0462
257 IMMUNE THROMBOCYTOPENIC PURPURA 132 0.0459
258 ABDOMINAL MASS 86 0.0459
259 DRUG RESISTANCE 798 0.0457
260 HAEMOGLOBIN ABNORMAL 192 0.0451
261 MALNUTRITION 353 0.0451
262 HAEMOLYTIC ANAEMIA 317 0.0450
263 GUILLAIN-BARRE SYNDROME 151 0.0448
264 DEAFNESS NEUROSENSORY 107 0.0448
265 HEPATITIS B REACTIVATION 94 0.0448
266 WHITE BLOOD CELL COUNT ABNORMAL 194 0.0448
267 LUNG INFILTRATION 346 0.0446
268 BRONCHOSPASM 498 0.0445
269 ORGANISING PNEUMONIA 139 0.0444
270 HYPOVOLAEMIC SHOCK 156 0.0441
271 URINARY TRACT OBSTRUCTION 77 0.0439
272 WHITE BLOOD CELL COUNT DECREASED 3336 0.0436
273 PLEURAL EFFUSION 2031 0.0435
274 OESOPHAGEAL VARICES HAEMORRHAGE 73 0.0435
275 THROMBOPHLEBITIS 125 0.0433
276 THROMBOCYTOSIS 109 0.0432
277 ALOPECIA 6406 0.0430
278 COLITIS 1048 0.0430
279 PLEURITIC PAIN 96 0.0427
280 ENTEROCOCCAL INFECTION 144 0.0426
281 NECROSIS 185 0.0421
282 COLITIS ISCHAEMIC 212 0.0419
283 ANOREXIA 536 0.0415
284 NECROTISING FASCIITIS 102 0.0412
285 HAEMOPTYSIS 889 0.0410
286 MYOSITIS 248 0.0407
287 CLOSTRIDIUM DIFFICILE COLITIS 317 0.0407
288 HEPATOTOXICITY 616 0.0406
289 ESCHERICHIA SEPSIS 92 0.0406
290 THROMBOTIC THROMBOCYTOPENIC PURPURA 121 0.0405
291 UROSEPSIS 268 0.0402
292 STAPHYLOCOCCAL SEPSIS 160 0.0400
293 PLATELET COUNT ABNORMAL 160 0.0399
294 PULMONARY EMBOLISM 3065 0.0397
295 PSEUDOMEMBRANOUS COLITIS 74 0.0395
296 PULSE ABSENT 153 0.0395
297 ACUTE CORONARY SYNDROME 268 0.0393
298 GENERAL PHYSICAL HEALTH DETERIORATION 2893 0.0389
299 SUDDEN DEATH 352 0.0388
300 OESOPHAGEAL CANDIDIASIS 108 0.0387
301 SINUS TACHYCARDIA 418 0.0384
302 SYSTEMIC INFLAMMATORY RESPONSE SYNDROME 115 0.0384
303 WHITE BLOOD CELL DISORDER 74 0.0382
304 HYPOPHAGIA 688 0.0382
305 HEPATIC CYTOLYSIS 70 0.0381
306 HEPATIC FUNCTION ABNORMAL 969 0.0378
307 TUMOUR MARKER INCREASED 113 0.0375
308 DRUG TOXICITY 510 0.0374
309 MULTIPLE ORGAN DYSFUNCTION SYNDROME 605 0.0374
310 ELECTROCARDIOGRAM ST SEGMENT DEPRESSION 68 0.0373
311 RENAL FAILURE ACUTE 1585 0.0373
312 ENCEPHALOPATHY 654 0.0373
313 RESPIRATORY FAILURE 2093 0.0372
314 BILE DUCT OBSTRUCTION 71 0.0372
315 TOXIC ENCEPHALOPATHY 121 0.0371
316 TACHYARRHYTHMIA 76 0.0370
317 HEPATITIS B 178 0.0369
318 HYPOXIA 943 0.0368
319 DUODENAL ULCER 201 0.0367
320 ORAL CANDIDIASIS 333 0.0367
321 NEPHRITIS 85 0.0367
322 COMPUTERISED TOMOGRAM ABNORMAL 69 0.0364
323 HISTIOCYTOSIS HAEMATOPHAGIC 110 0.0364
324 CARBOHYDRATE ANTIGEN 125 INCREASED 95 0.0363
325 HAEMATOCRIT DECREASED 589 0.0361
326 EJECTION FRACTION DECREASED 405 0.0359
327 BLOOD LACTATE DEHYDROGENASE INCREASED 467 0.0359
328 PROCTALGIA 168 0.0357
329 RENAL TUBULAR NECROSIS 260 0.0357
330 STAPHYLOCOCCAL BACTERAEMIA 104 0.0357
331 ADRENAL INSUFFICIENCY 253 0.0355
332 SUPRAVENTRICULAR TACHYCARDIA 265 0.0354
333 VENTRICULAR DYSFUNCTION 68 0.0352
334 BLOOD SODIUM DECREASED 491 0.0352
335 NON-CARDIAC CHEST PAIN 98 0.0352
336 LARYNGEAL OEDEMA 165 0.0351
337 ANAPHYLACTIC SHOCK 617 0.0349
338 CARDIAC TAMPONADE 124 0.0349
339 JAUNDICE CHOLESTATIC 96 0.0348
340 FIBROSIS 82 0.0348
341 VENTRICULAR HYPOKINESIA 87 0.0348
342 PULMONARY FIBROSIS 446 0.0346
343 ABDOMINAL TENDERNESS 134 0.0345
344 CANDIDIASIS 137 0.0341
345 DEVICE RELATED INFECTION 422 0.0340
346 DEEP VEIN THROMBOSIS 1855 0.0338
347 PAPILLOEDEMA 116 0.0338
348 PNEUMOCYSTIS JIROVECII PNEUMONIA 207 0.0337
349 AREFLEXIA 72 0.0335
350 ESCHERICHIA INFECTION 185 0.0332
351 MYOCARDITIS 214 0.0330
352 CARDIOMYOPATHY 382 0.0330
353 HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS 91 0.0330
354 RESPIRATORY DISTRESS 703 0.0328
355 PULMONARY ALVEOLAR HAEMORRHAGE 122 0.0328
356 LYMPHOCYTE COUNT DECREASED 420 0.0326
357 BREAST CANCER METASTATIC 253 0.0325
358 DUODENITIS 77 0.0323
359 HEPATIC CYST 83 0.0322
360 FAECALOMA 126 0.0322
361 FISTULA 242 0.0321
362 BONE MARROW DISORDER 68 0.0319
363 HAEMOGLOBIN DECREASED 2474 0.0317
364 HYPERTENSIVE CRISIS 272 0.0317
365 AGRANULOCYTOSIS 386 0.0316
366 SARCOIDOSIS 111 0.0316
367 CHEST X-RAY ABNORMAL 83 0.0316
368 HYPERURICAEMIA 96 0.0315
369 MULTI-ORGAN FAILURE 545 0.0314
370 PERICARDIAL EFFUSION 516 0.0314
371 BREAST CANCER RECURRENT 70 0.0313
372 TACHYPNOEA 296 0.0313
373 HYPERCALCAEMIA 284 0.0312
374 DERMATITIS 423 0.0310
375 CONGESTIVE CARDIOMYOPATHY 123 0.0310
376 FLUID INTAKE REDUCED 104 0.0310
377 SKIN REACTION 318 0.0309
378 FIBRIN D DIMER INCREASED 82 0.0309
379 RECTAL CANCER 72 0.0308
380 BLOOD PHOSPHORUS DECREASED 75 0.0307
381 ASPIRATION 239 0.0307
382 PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY 192 0.0307
383 ATRIAL FLUTTER 194 0.0306
384 DYSPHAGIA 2079 0.0304
385 SPLENOMEGALY 268 0.0303
386 INFUSION RELATED REACTION 1258 0.0302
387 TROPONIN INCREASED 145 0.0302
388 BLOOD CREATININE INCREASED 1506 0.0300
389 BLOOD BILIRUBIN INCREASED 643 0.0299
390 CEREBRAL INFARCTION 568 0.0298
391 HYPERTHERMIA 176 0.0298
392 LEUKOCYTOSIS 400 0.0297
393 WOUND INFECTION 192 0.0296
394 CARDIOPULMONARY FAILURE 96 0.0296
395 NEPHROTIC SYNDROME 151 0.0295
396 VOMITING 10052 0.0295
397 LEFT VENTRICULAR FAILURE 76 0.0295
398 BONE LESION 79 0.0295
399 OLIGURIA 143 0.0294
400 INTESTINAL OBSTRUCTION 755 0.0294
401 AMYLASE INCREASED 76 0.0293
402 NAIL DISORDER 166 0.0293
403 PHLEBITIS 122 0.0292
404 HEPATIC FAILURE 689 0.0290
405 PANCREATIC CARCINOMA METASTATIC 68 0.0290
406 SHOCK 477 0.0289
407 PERITONITIS 471 0.0286
408 ISCHAEMIA 108 0.0286
409 PNEUMONIA ASPIRATION 518 0.0285
410 PYREXIA 7267 0.0285
411 CARDIAC FAILURE ACUTE 127 0.0284
412 BLOOD UREA INCREASED 397 0.0284
413 BLOOD ALKALINE PHOSPHATASE INCREASED 576 0.0281
414 PROTEIN URINE PRESENT 102 0.0281
415 DEAFNESS 526 0.0281
416 BRONCHOPULMONARY ASPERGILLOSIS 144 0.0280
417 METABOLIC DISORDER 124 0.0279
418 PNEUMONIA BACTERIAL 151 0.0278
419 BLOOD CALCIUM DECREASED 243 0.0278
420 BREATH SOUNDS ABNORMAL 92 0.0277
421 TONGUE OEDEMA 82 0.0277
422 APLASTIC ANAEMIA 109 0.0276
423 TRANSAMINASES INCREASED 473 0.0276
424 PSEUDOMONAS INFECTION 159 0.0276
425 BRONCHOPNEUMONIA 94 0.0274
426 TRISMUS 108 0.0273
427 OXYGEN SATURATION DECREASED 991 0.0273
428 NEUTROPHIL COUNT INCREASED 212 0.0272
429 BODY TEMPERATURE INCREASED 433 0.0272
430 ASPARTATE AMINOTRANSFERASE INCREASED 1126 0.0271
431 GRANULOCYTOPENIA 136 0.0270
432 ACUTE RESPIRATORY FAILURE 350 0.0269
433 PROTEIN TOTAL DECREASED 77 0.0268
434 OVARIAN CANCER 197 0.0266
435 PATHOLOGICAL FRACTURE 101 0.0263
436 MENTAL STATUS CHANGES 573 0.0262
437 FLANK PAIN 183 0.0262
438 CHOLESTASIS 360 0.0262
439 DECREASED APPETITE 4199 0.0262
440 ACUTE PULMONARY OEDEMA 117 0.0261
441 ENDOCARDITIS 98 0.0261
442 ANAPHYLACTOID REACTION 83 0.0260
443 HYPERNATRAEMIA 94 0.0260
444 OESOPHAGEAL ULCER 81 0.0260
445 RENAL IMPAIRMENT 1502 0.0256
446 ACUTE KIDNEY INJURY 2637 0.0255
447 FOLLICULITIS 107 0.0255
448 ACIDOSIS 151 0.0255
449 TACHYCARDIA 1674 0.0255
450 REFUSAL OF TREATMENT BY PATIENT 131 0.0254
451 MYOCARDIAL ISCHAEMIA 251 0.0253
452 NEUTROPHILIA 89 0.0253
453 RASH PUSTULAR 158 0.0253
454 BLOOD CREATINE INCREASED 82 0.0252
455 ALANINE AMINOTRANSFERASE INCREASED 1206 0.0252
456 CIRCULATORY COLLAPSE 349 0.0251
457 LUNG INFECTION 393 0.0251
458 HAEMATEMESIS 499 0.0250
459 HAEMOLYSIS 148 0.0249
460 DIARRHOEA 11092 0.0249
461 CARDIOGENIC SHOCK 235 0.0248
462 C-REACTIVE PROTEIN INCREASED 605 0.0246
463 HEPATIC ENCEPHALOPATHY 178 0.0245
464 CANDIDA INFECTION 266 0.0245
465 VENTRICULAR FIBRILLATION 214 0.0245
466 GASTROINTESTINAL INFLAMMATION 128 0.0244
467 OESOPHAGEAL PAIN 76 0.0242
468 DIVERTICULUM INTESTINAL 77 0.0242
469 ENCEPHALITIS 118 0.0242
470 GAMMA-GLUTAMYLTRANSFERASE INCREASED 440 0.0242
471 HAEMODYNAMIC INSTABILITY 123 0.0241
472 HYPERGLYCAEMIA 674 0.0241
473 CATHETER SITE INFECTION 67 0.0240
474 ACUTE MYOCARDIAL INFARCTION 587 0.0239
475 CYANOSIS 294 0.0239
476 PROTHROMBIN TIME PROLONGED 128 0.0239
477 HYPOTENSION 3539 0.0239
478 ABDOMINAL PAIN 4047 0.0238
479 LUNG NEOPLASM 87 0.0237
480 PURPURA 165 0.0237
481 HYPERTRIGLYCERIDAEMIA 99 0.0236
482 AZOTAEMIA 69 0.0236
483 HEPATOCELLULAR INJURY 289 0.0234
484 PYELONEPHRITIS 146 0.0234
485 RETINOPATHY 68 0.0234
486 BLOOD POTASSIUM DECREASED 535 0.0233
487 NEOPLASM 181 0.0231
488 CHOLECYSTITIS ACUTE 101 0.0229
489 ANURIA 161 0.0228
490 SPINAL CORD COMPRESSION 68 0.0227
491 ATAXIA 212 0.0226
492 EPISTAXIS 1286 0.0226
493 INFECTION 2194 0.0225
494 TUBULOINTERSTITIAL NEPHRITIS 304 0.0225
495 LYMPHOEDEMA 106 0.0223
496 HEMIPARESIS 306 0.0222
497 URINE OUTPUT DECREASED 156 0.0221
498 CHOLECYSTITIS 197 0.0221
499 HAEMATURIA 612 0.0220
500 HERPES SIMPLEX 104 0.0219
501 BLOOD LACTIC ACID INCREASED 78 0.0219
502 ABSCESS 247 0.0219
503 CREATININE RENAL CLEARANCE DECREASED 72 0.0219
504 LYMPHADENOPATHY 566 0.0218
505 ATRIAL FIBRILLATION 1570 0.0218
506 HYPOGAMMAGLOBULINAEMIA 76 0.0218
507 HEPATIC NECROSIS 69 0.0216
508 CHILLS 1865 0.0216
509 SKIN NECROSIS 89 0.0215
510 RASH MACULO-PAPULAR 337 0.0215
511 MOUTH ULCERATION 316 0.0214
512 CEREBRAL ATROPHY 69 0.0213
513 SHOCK HAEMORRHAGIC 123 0.0212
514 NAUSEA 12128 0.0211
515 PHARYNGOLARYNGEAL PAIN 112 0.0211
516 NEUROLOGICAL SYMPTOM 87 0.0210
517 PERICARDITIS 178 0.0210
518 PULMONARY MASS 215 0.0209
519 PETECHIAE 164 0.0208
520 PRODUCT USE IN UNAPPROVED INDICATION 2754 0.0207
521 ANAPHYLACTIC REACTION 760 0.0206
522 ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED 87 0.0205
523 THROAT TIGHTNESS 412 0.0205
524 BRAIN OEDEMA 195 0.0204
525 TOXIC SKIN ERUPTION 153 0.0203
526 RENAL FAILURE 2240 0.0202
527 APHTHOUS ULCER 88 0.0201
528 ORTHOSTATIC HYPOTENSION 264 0.0201
529 RENAL FAILURE CHRONIC 155 0.0201
530 HYPERKALAEMIA 531 0.0201
531 PLATELET COUNT INCREASED 185 0.0200
532 LIPASE INCREASED 118 0.0200
533 HYDROCEPHALUS 83 0.0199
534 CARDIO-RESPIRATORY ARREST 691 0.0199
535 LIVER INJURY 265 0.0198
536 BACTERIAL INFECTION 247 0.0196
537 STREPTOCOCCAL INFECTION 73 0.0196
538 DYSARTHRIA 569 0.0195
539 PIGMENTATION DISORDER 85 0.0194
540 GRAFT VERSUS HOST DISEASE 108 0.0191
541 PNEUMONIA 4391 0.0191
542 ISCHAEMIC STROKE 267 0.0191
543 JAUNDICE 425 0.0191
544 DRUG-INDUCED LIVER INJURY 324 0.0190
545 STAPHYLOCOCCAL INFECTION 499 0.0190
546 GASTROENTERITIS 206 0.0189
547 HAEMODIALYSIS 151 0.0189
548 HEPATITIS 358 0.0189
549 ASTHENIA 5177 0.0188
550 TOXIC EPIDERMAL NECROLYSIS 205 0.0188
551 CONSTIPATION 2778 0.0188
552 DYSPNOEA EXERTIONAL 477 0.0187
553 ORAL PAIN 317 0.0187
554 GENERALISED OEDEMA 162 0.0185
555 RALES 80 0.0184
556 RED BLOOD CELL COUNT DECREASED 372 0.0183
557 ANAL FISTULA 66 0.0182
558 HEPATOMEGALY 146 0.0182
559 ERYTHEMA MULTIFORME 130 0.0181
560 SYNCOPE 1383 0.0181
561 CYTOMEGALOVIRUS INFECTION 222 0.0181
562 ALTERED STATE OF CONSCIOUSNESS 267 0.0181
563 VASCULITIS 145 0.0178
564 SKIN HYPERPIGMENTATION 119 0.0178
565 DIARRHOEA HAEMORRHAGIC 122 0.0176
566 RESPIRATORY RATE INCREASED 115 0.0175
567 CHOKING SENSATION 73 0.0175
568 METABOLIC ACIDOSIS 387 0.0175
569 GENERALISED ERYTHEMA 100 0.0175
570 HYPERTENSION 2688 0.0175
571 HYPOTHYROIDISM 376 0.0175
572 FOETAL GROWTH RESTRICTION 73 0.0173
573 OFF LABEL USE 8146 0.0172
574 NO THERAPEUTIC RESPONSE 210 0.0172
575 WHITE BLOOD CELL COUNT INCREASED 515 0.0172
576 PARAESTHESIA ORAL 176 0.0172
577 PARAESTHESIA 2020 0.0171
578 ANGIOPATHY 78 0.0171
579 GASTRITIS 343 0.0171
580 THERAPY NON-RESPONDER 411 0.0171
581 DYSPNOEA 7093 0.0170
582 MOUTH HAEMORRHAGE 91 0.0169
583 UNRESPONSIVE TO STIMULI 328 0.0169
584 PALLOR 321 0.0169
585 MELAENA 293 0.0169
586 COAGULOPATHY 223 0.0168
587 SUBARACHNOID HAEMORRHAGE 129 0.0168
588 POST PROCEDURAL COMPLICATION 251 0.0168
589 PRESYNCOPE 294 0.0167
590 EYELID PTOSIS 120 0.0165
591 EMPHYSEMA 133 0.0165
592 RETINAL HAEMORRHAGE 90 0.0165
593 COLON CANCER 183 0.0165
594 RESPIRATORY TRACT INFECTION 284 0.0164
595 UPPER GASTROINTESTINAL HAEMORRHAGE 220 0.0164
596 PLEURISY 80 0.0163
597 ERYTHEMA 2492 0.0163
598 LUNG DISORDER 561 0.0163
599 CARDIAC FAILURE 980 0.0162
600 FLUSHING 1345 0.0162
601 TOXICITY TO VARIOUS AGENTS 1886 0.0161
602 FACE OEDEMA 210 0.0160
603 PANCREATITIS ACUTE 259 0.0159
604 SKIN MASS 70 0.0158
605 BLOOD PRESSURE DIASTOLIC DECREASED 81 0.0158
606 DELIRIUM 379 0.0156
607 OROPHARYNGEAL DISCOMFORT 73 0.0155
608 PRODUCTIVE COUGH 490 0.0154
609 HEPATITIS CHOLESTATIC 68 0.0153
610 MITRAL VALVE INCOMPETENCE 136 0.0153
611 IMMUNOSUPPRESSION 82 0.0153
612 SINUS BRADYCARDIA 114 0.0152
613 MUSCULOSKELETAL CHEST PAIN 173 0.0152
614 LIVER DISORDER 490 0.0152
615 HEARING IMPAIRED 91 0.0151
616 GASTRIC ULCER HAEMORRHAGE 72 0.0151
617 CARDIAC ARREST 997 0.0151
618 HYPERSENSITIVITY 2048 0.0151
619 ACUTE HEPATIC FAILURE 147 0.0151
620 GASTRIC ULCER 227 0.0151
621 AUTOIMMUNE HEPATITIS 72 0.0151
622 PULMONARY OEDEMA 521 0.0150
623 COLD SWEAT 201 0.0149
624 STATUS EPILEPTICUS 125 0.0148
625 COVID-19 PNEUMONIA 85 0.0147
626 ORAL DISORDER 81 0.0147
627 HEMIPLEGIA 97 0.0147
628 HEPATITIS ACUTE 73 0.0147
629 POSTOPERATIVE WOUND INFECTION 68 0.0146
630 OEDEMA 571 0.0146
631 TEMPERATURE INTOLERANCE 101 0.0145
632 APHAGIA 70 0.0145
633 GRAND MAL CONVULSION 134 0.0145
634 SKIN INFECTION 112 0.0145
635 APHASIA 338 0.0145
636 OSTEONECROSIS OF JAW 302 0.0144
637 DERMATITIS EXFOLIATIVE 66 0.0144
638 DEPRESSED LEVEL OF CONSCIOUSNESS 427 0.0143
639 DYSURIA 405 0.0143
640 RECTAL HAEMORRHAGE 483 0.0143
641 MENINGITIS 70 0.0143
642 VENTRICULAR TACHYCARDIA 177 0.0142
643 DRUG ERUPTION 174 0.0142
644 TREATMENT FAILURE 748 0.0141
645 HYPERTHYROIDISM 145 0.0141
646 SKIN DISORDER 307 0.0139
647 CHEST PAIN 2004 0.0139
648 GENERALISED TONIC-CLONIC SEIZURE 151 0.0139
649 RENAL CYST 87 0.0138
650 BONE PAIN 621 0.0138
651 CLOSTRIDIUM DIFFICILE INFECTION 198 0.0136
652 TRICUSPID VALVE INCOMPETENCE 80 0.0136
653 BLOOD PRESSURE DECREASED 667 0.0136
654 GASTROINTESTINAL DISORDER 739 0.0135
655 EYELID OEDEMA 136 0.0135
656 ARTERIAL OCCLUSIVE DISEASE 86 0.0135
657 HEPATIC STEATOSIS 184 0.0134
658 APPENDICITIS 85 0.0134
659 ASPHYXIA 77 0.0134
660 CHEST DISCOMFORT 974 0.0133
661 BLOOD DISORDER 79 0.0133
662 URINARY RETENTION 327 0.0133
663 NEURALGIA 224 0.0133
664 SKIN FISSURES 130 0.0132
665 ARTERIOSCLEROSIS CORONARY ARTERY 66 0.0131
666 FEELING HOT 594 0.0131
667 CELLULITIS 503 0.0130
668 CONJUNCTIVITIS 147 0.0130
669 GLOMERULAR FILTRATION RATE DECREASED 94 0.0128
670 SQUAMOUS CELL CARCINOMA 90 0.0127
671 MASS 137 0.0127
672 URINARY TRACT INFECTION 1510 0.0127
673 DERMATITIS BULLOUS 68 0.0127
674 GASTRIC HAEMORRHAGE 123 0.0126
675 HAEMORRHAGE 948 0.0126
676 THROMBOSIS 786 0.0126
677 EPILEPSY 264 0.0125
678 ANGINA PECTORIS 294 0.0125
679 INCONTINENCE 100 0.0124
680 GASTROINTESTINAL HAEMORRHAGE 885 0.0124
681 FACIAL PARALYSIS 71 0.0124
682 SENSORY LOSS 78 0.0124
683 LEUKAEMIA 84 0.0123
684 DECUBITUS ULCER 78 0.0123
685 OEDEMA PERIPHERAL 1227 0.0123
686 NEPHROPATHY 94 0.0122
687 ABDOMINAL PAIN LOWER 237 0.0122
688 TINNITUS 415 0.0121
689 DIVERTICULITIS 242 0.0121
690 PROCEDURAL COMPLICATION 79 0.0120
691 NERVOUS SYSTEM DISORDER 312 0.0120
692 FATIGUE 6533 0.0120
693 BODY TEMPERATURE DECREASED 91 0.0119
694 RHINITIS 69 0.0119
695 RESPIRATORY DISORDER 264 0.0119
696 LOSS OF CONSCIOUSNESS 1162 0.0118
697 LYMPHOMA 136 0.0118
698 IMPAIRED HEALING 273 0.0118
699 TENDERNESS 93 0.0117
700 PHARYNGITIS 111 0.0117
701 GROIN PAIN 79 0.0116
702 WEIGHT DECREASED 2346 0.0116
703 SPINAL COMPRESSION FRACTURE 79 0.0116
704 FORMICATION 66 0.0115
705 HYPERHIDROSIS 1123 0.0114
706 TASTE DISORDER 88 0.0114
707 CONFUSIONAL STATE 1404 0.0114
708 DYSPHONIA 483 0.0113
709 HYPERAESTHESIA 75 0.0113
710 LETHARGY 511 0.0113
711 ULCER 134 0.0113
712 ELECTROCARDIOGRAM ABNORMAL 69 0.0112
713 DYSGEUSIA 618 0.0112
714 INTERNATIONAL NORMALISED RATIO INCREASED 293 0.0112
715 INFUSION SITE PAIN 81 0.0112
716 RASH 3337 0.0112
717 HYPOTHERMIA 87 0.0112
718 LOWER GASTROINTESTINAL HAEMORRHAGE 70 0.0111
719 INTENTIONAL PRODUCT USE ISSUE 562 0.0111
720 CEREBRAL HAEMORRHAGE 306 0.0110
721 POLYURIA 68 0.0110
722 PERIPHERAL COLDNESS 116 0.0110
723 RETCHING 170 0.0110
724 RETINAL DETACHMENT 72 0.0108
725 DIPLOPIA 204 0.0108
726 COUGH 2060 0.0108
727 SKIN LESION 205 0.0107
728 SPINAL OSTEOARTHRITIS 74 0.0107
729 DISORIENTATION 349 0.0107
730 ARTERIOSCLEROSIS 80 0.0107
731 VENTRICULAR EXTRASYSTOLES 87 0.0106
732 SKIN ULCER 204 0.0106
733 THERAPEUTIC RESPONSE DECREASED 448 0.0105
734 DIALYSIS 119 0.0104
735 COMA 386 0.0104
736 INFLAMMATION 348 0.0103
737 GINGIVAL BLEEDING 98 0.0102
738 BLOOD POTASSIUM INCREASED 126 0.0102
739 PULMONARY HYPERTENSION 168 0.0102
740 OSTEONECROSIS 288 0.0102
741 RASH ERYTHEMATOUS 306 0.0102
742 ARRHYTHMIA 378 0.0102
743 DEVICE OCCLUSION 72 0.0101
744 CARDIOMEGALY 106 0.0100
745 BRADYCARDIA 415 0.0099
746 TRANSIENT ISCHAEMIC ATTACK 269 0.0099
747 ILL-DEFINED DISORDER 294 0.0099
748 OBSTRUCTIVE AIRWAYS DISORDER 80 0.0098
749 PELVIC PAIN 139 0.0098
750 HYPOTONIA 80 0.0098
751 LACRIMATION INCREASED 188 0.0097
752 BACK PAIN 1673 0.0097
753 HAEMORRHAGE INTRACRANIAL 122 0.0097
754 POST PROCEDURAL HAEMORRHAGE 90 0.0096
755 DEATH 5877 0.0096
756 NEOPLASM MALIGNANT 447 0.0096
757 LUNG NEOPLASM MALIGNANT 313 0.0096
758 EMOTIONAL DISTRESS 1012 0.0095
759 CONVULSION 545 0.0095
760 PARALYSIS 106 0.0095
761 NODULE 87 0.0094
762 URINARY INCONTINENCE 212 0.0094
763 DERMATITIS ALLERGIC 78 0.0094
764 DRUG INTOLERANCE 625 0.0094
765 LOWER RESPIRATORY TRACT INFECTION 277 0.0093
766 MOTOR DYSFUNCTION 70 0.0093
767 SPEECH DISORDER 377 0.0092
768 HAEMORRHOIDS 137 0.0092
769 ABDOMINAL DISTENSION 685 0.0092
770 LIVER FUNCTION TEST INCREASED 117 0.0092
771 FUNGAL INFECTION 219 0.0091
772 RESPIRATORY ARREST 219 0.0091
773 LIVER FUNCTION TEST ABNORMAL 232 0.0091
774 DRUG INTERACTION 1095 0.0091
775 BLOOD PRESSURE SYSTOLIC INCREASED 120 0.0090
776 COGNITIVE DISORDER 305 0.0090
777 MUSCULAR WEAKNESS 758 0.0090
778 LACTIC ACIDOSIS 190 0.0089
779 HYPOAESTHESIA 1000 0.0089
780 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 320 0.0089
781 PLASMA CELL MYELOMA 240 0.0089
782 HAEMATOMA 185 0.0088
783 STEVENS-JOHNSON SYNDROME 156 0.0087
784 SENSORY DISTURBANCE 114 0.0087
785 BLINDNESS 250 0.0087
786 HEPATIC CIRRHOSIS 112 0.0086
787 PULMONARY CONGESTION 84 0.0086
788 CYSTITIS 212 0.0086
789 HIATUS HERNIA 89 0.0085
790 HYPOACUSIS 239 0.0085
791 HEART RATE INCREASED 614 0.0085
792 HAEMATOCHEZIA 309 0.0084
793 FEEDING DISORDER 100 0.0084
794 DRUG EFFECT INCOMPLETE 302 0.0083
795 IMMUNODEFICIENCY 70 0.0082
796 MUSCLE RIGIDITY 74 0.0082
797 HERPES ZOSTER 349 0.0081
798 MUSCULOSKELETAL PAIN 375 0.0081
799 MALAISE 2672 0.0079
800 SPINAL PAIN 66 0.0079
801 BONE DISORDER 118 0.0078
802 TOOTH EXTRACTION 74 0.0078
803 ANXIETY 1699 0.0077
804 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 306 0.0077
805 OSTEOMYELITIS 112 0.0077
806 PRURITUS 1840 0.0077
807 DYSPEPSIA 540 0.0076
808 ABDOMINAL PAIN UPPER 1124 0.0076
809 RENAL DISORDER 261 0.0076
810 FLUID OVERLOAD 111 0.0076
811 EATING DISORDER 120 0.0076
812 PULMONARY ARTERIAL HYPERTENSION 87 0.0075
813 HOT FLUSH 383 0.0074
814 OROPHARYNGEAL PAIN 478 0.0074
815 HYPOAESTHESIA ORAL 84 0.0074
816 HEPATIC ENZYME INCREASED 349 0.0073
817 SUBDURAL HAEMATOMA 83 0.0072
818 SEIZURE 526 0.0071
819 UPPER RESPIRATORY TRACT INFECTION 237 0.0071
820 BLOOD CREATINE PHOSPHOKINASE INCREASED 169 0.0071
821 OSTEOPENIA 80 0.0070
822 VERTIGO 330 0.0069
823 FULL BLOOD COUNT DECREASED 91 0.0069
824 RESTLESSNESS 194 0.0069
825 PAIN IN JAW 154 0.0069
826 PAIN 3119 0.0068
827 CONDITION AGGRAVATED 1280 0.0068
828 TOOTHACHE 91 0.0068
829 WHEEZING 271 0.0068
830 RASH GENERALISED 176 0.0068
831 PANCREATITIS 280 0.0068
832 LOCAL SWELLING 117 0.0067
833 FEELING COLD 140 0.0067
834 NIGHT SWEATS 149 0.0067
835 BLOOD URINE PRESENT 98 0.0066
836 BLOOD PRESSURE INCREASED 739 0.0066
837 CENTRAL NERVOUS SYSTEM LESION 75 0.0064
838 PREMATURE BABY 147 0.0063
839 CHOLELITHIASIS 161 0.0063
840 DIZZINESS 2295 0.0062
841 CEREBROVASCULAR ACCIDENT 846 0.0062
842 MYALGIA 786 0.0062
843 COORDINATION ABNORMAL 73 0.0061
844 NECK PAIN 256 0.0061
845 ELECTROCARDIOGRAM QT PROLONGED 162 0.0061
846 CARDIOVASCULAR DISORDER 136 0.0061
847 PREMATURE DELIVERY 70 0.0061
848 SKIN EXFOLIATION 342 0.0060
849 ANGIOEDEMA 194 0.0060
850 DIABETIC KETOACIDOSIS 108 0.0060
851 HYPOGLYCAEMIA 226 0.0059
852 RHABDOMYOLYSIS 186 0.0059
853 WOUND 99 0.0058
854 FAECES DISCOLOURED 96 0.0058
855 LABORATORY TEST ABNORMAL 122 0.0057
856 CHROMATURIA 100 0.0057
857 EAR PAIN 80 0.0057
858 MYOCARDIAL INFARCTION 862 0.0057
859 SWOLLEN TONGUE 139 0.0057
860 ECZEMA 109 0.0056
861 PRURITUS GENERALISED 121 0.0056
862 TREMOR 717 0.0056
863 DRY SKIN 499 0.0056
864 THROAT IRRITATION 172 0.0055
865 BLOOD COUNT ABNORMAL 90 0.0055
866 DRY MOUTH 321 0.0055
867 PHARYNGEAL OEDEMA 82 0.0055
868 GASTRIC CANCER 108 0.0054
869 PALPITATIONS 473 0.0054
870 CORONARY ARTERY DISEASE 148 0.0054
871 ORAL HERPES 69 0.0054
872 RASH MACULAR 130 0.0054
873 BLOOD PRESSURE ABNORMAL 70 0.0054
874 POLLAKIURIA 170 0.0054
875 RASH PAPULAR 95 0.0054
876 DRUG HYPERSENSITIVITY 797 0.0053
877 AGITATION 318 0.0053
878 VAGINAL HAEMORRHAGE 185 0.0052
879 FLATULENCE 217 0.0052
880 DISCOMFORT 193 0.0052
881 URTICARIA 596 0.0051
882 MUSCLE TWITCHING 90 0.0051
883 RHINORRHOEA 225 0.0050
884 PAIN IN EXTREMITY 1104 0.0049
885 SWELLING FACE 239 0.0049
886 VISUAL ACUITY REDUCED 145 0.0049
887 GASTROOESOPHAGEAL REFLUX DISEASE 285 0.0049
888 BRONCHITIS 279 0.0049
889 AGEUSIA 89 0.0048
890 PRODUCT USE ISSUE 607 0.0048
891 VIRAL INFECTION 109 0.0048
892 CARDIAC FAILURE CONGESTIVE 342 0.0048
893 SKIN DISCOLOURATION 166 0.0047
894 BLISTER 190 0.0047
895 RASH PRURITIC 182 0.0047
896 LIP SWELLING 115 0.0046
897 HEART RATE IRREGULAR 85 0.0046
898 LIMB DISCOMFORT 99 0.0045
899 MUSCLE SPASMS 614 0.0045
900 BALANCE DISORDER 293 0.0044
901 DEPRESSION 797 0.0044
902 ADVERSE EVENT 303 0.0043
903 FALL 1037 0.0042
904 GAIT DISTURBANCE 605 0.0042
905 VISUAL IMPAIRMENT 348 0.0041
906 SOMNOLENCE 621 0.0041
907 ARTHRALGIA 1143 0.0041
908 RENAL INJURY 109 0.0040
909 ACTIVITIES OF DAILY LIVING IMPAIRED 79 0.0040
910 VISION BLURRED 393 0.0040
911 DRY EYE 107 0.0040
912 CONTRAINDICATED PRODUCT ADMINISTERED 72 0.0040
913 HEART RATE DECREASED 102 0.0040
914 SWELLING 255 0.0039
915 HEADACHE 1782 0.0038
916 PSYCHOTIC DISORDER 87 0.0038
917 DISTURBANCE IN ATTENTION 159 0.0037
918 TREATMENT NONCOMPLIANCE 132 0.0037
919 ABDOMINAL DISCOMFORT 433 0.0037
920 DEPRESSED MOOD 139 0.0037
921 DIABETES MELLITUS 220 0.0037
922 BURNING SENSATION 194 0.0036
923 FOETAL EXPOSURE DURING PREGNANCY 211 0.0036
924 OESOPHAGEAL CARCINOMA 81 0.0036
925 CHRONIC KIDNEY DISEASE 231 0.0035
926 DRUG INEFFECTIVE 3258 0.0035
927 SLEEP DISORDER 165 0.0034
928 COVID-19 232 0.0034
929 MOVEMENT DISORDER 81 0.0033
930 FLUID RETENTION 128 0.0033
931 HEAD INJURY 75 0.0033
932 ADVERSE DRUG REACTION 187 0.0033
933 PANCREATIC CARCINOMA 74 0.0032
934 CONTUSION 223 0.0032
935 NEPHROLITHIASIS 103 0.0032
936 CARDIAC DISORDER 234 0.0032
937 MATERNAL EXPOSURE DURING PREGNANCY 164 0.0031
938 ABASIA 77 0.0031
939 SINUSITIS 226 0.0031
940 DYSKINESIA 96 0.0031
941 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 102 0.0031
942 FEMUR FRACTURE 77 0.0030
943 PERIPHERAL SWELLING 307 0.0030
944 HIP FRACTURE 70 0.0030
945 BLOOD GLUCOSE INCREASED 446 0.0030
946 INSOMNIA 609 0.0030
947 OCULAR HYPERAEMIA 89 0.0029
948 OSTEOARTHRITIS 91 0.0029
949 AMNESIA 150 0.0029
950 HALLUCINATION 153 0.0029
951 MEDICATION ERROR 120 0.0028
952 EYE SWELLING 74 0.0027
953 COLITIS ULCERATIVE 66 0.0027
954 EXPOSURE DURING PREGNANCY 111 0.0026
955 NASAL CONGESTION 101 0.0026
956 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 67 0.0025
957 MENTAL DISORDER 83 0.0025
958 MOBILITY DECREASED 121 0.0023
959 INFLUENZA LIKE ILLNESS 156 0.0023
960 COLORECTAL CANCER 99 0.0023
961 UNEVALUABLE EVENT 140 0.0023
962 EYE PAIN 82 0.0023
963 INFLUENZA 168 0.0023
964 FEELING ABNORMAL 420 0.0022
965 NASOPHARYNGITIS 278 0.0022
966 OSTEOPOROSIS 70 0.0022
967 ARTHROPATHY 90 0.0022
968 WEIGHT INCREASED 352 0.0022
969 CATARACT 89 0.0021
970 MUSCULOSKELETAL STIFFNESS 136 0.0021
971 ARTHRITIS 118 0.0021
972 INCORRECT ROUTE OF DRUG ADMINISTRATION 75 0.0021
973 ACNE 128 0.0021
974 MEMORY IMPAIRMENT 210 0.0021
975 ABNORMAL BEHAVIOUR 69 0.0020
976 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 146 0.0019
977 ASTHMA 134 0.0019
978 AGGRESSION 77 0.0019
979 SURGERY 67 0.0019
980 JOINT SWELLING 151 0.0018
981 INJURY 101 0.0017
982 BREAST CANCER 136 0.0016
983 NO ADVERSE EVENT 143 0.0014
984 OVERDOSE 215 0.0013
985 MIGRAINE 85 0.0013
986 UNDERDOSE 67 0.0012
987 SKIN BURNING SENSATION 67 0.0012
988 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 147 0.0012
989 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 81 0.0011
990 PROSTATE CANCER 70 0.0011
991 HOSPITALISATION 89 0.0009
992 RHEUMATOID ARTHRITIS 68 0.0008
993 INCORRECT DOSE ADMINISTERED 106 0.0008
994 INJECTION SITE ERYTHEMA 69 0.0007
995 DRUG DOSE OMISSION 84 0.0005
996 INJECTION SITE PAIN 86 0.0004