Prostaglandin Analog [EPC]

Prostaglandin Analog [EPC] was reported 47433 times

Drugs of the Prostaglandin Analog [EPC] class are most commonly taken among patients reporting these side effects:

# Drug class Count Frequency
0 IRIS HYPERPIGMENTATION 116 0.6905
1 EYELASH HYPERPIGMENTATION 24 0.6316
2 EYELASH CHANGES 22 0.6286
3 GROWTH OF EYELASHES 381 0.6175
4 BLEPHARAL PIGMENTATION 215 0.6022
5 EYELASH THICKENING 55 0.5978
6 PENILE BURNING SENSATION 84 0.5250
7 TRABECULECTOMY 24 0.4444
8 INTRAOCULAR PRESSURE FLUCTUATION 58 0.4328
9 EYELASH DISCOLOURATION 60 0.3774
10 EYELIDS PRURITUS 488 0.3562
11 OCULAR SURFACE DISEASE 23 0.3485
12 ERYTHEMA OF EYELID 892 0.3321
13 EYELID IRRITATION 292 0.3143
14 INTRAOCULAR PRESSURE TEST ABNORMAL 111 0.2906
15 GLAUCOMA SURGERY 44 0.2857
16 TRICHIASIS 56 0.2800
17 EYELID THICKENING 33 0.2683
18 PRODUCT DROPPER ISSUE 176 0.2655
19 INTRAOCULAR PRESSURE INCREASED 2031 0.2627
20 LID SULCUS DEEPENED 41 0.2470
21 EYELID EXFOLIATION 74 0.2403
22 SCLERAL HYPERAEMIA 146 0.2374
23 INTRAOCULAR PRESSURE DECREASED 71 0.2276
24 EYELID SENSORY DISORDER 29 0.2248
25 EYELID PAIN 114 0.1884
26 EYELID SKIN DRYNESS 39 0.1857
27 KERATITIS HERPETIC 24 0.1805
28 EYE COLOUR CHANGE 86 0.1762
29 MADAROSIS 1247 0.1742
30 EYELID RASH 36 0.1722
31 TRICHORRHEXIS 268 0.1667
32 UTERINE HYPERTONUS 30 0.1648
33 EYE LASER SURGERY 44 0.1424
34 CHOROIDAL DETACHMENT 41 0.1424
35 OCULAR HYPERAEMIA 2930 0.1372
36 SKIN HYPERPIGMENTATION 480 0.1351
37 EYELID MARGIN CRUSTING 120 0.1320
38 DARK CIRCLES UNDER EYES 104 0.1248
39 IRIS DISORDER 54 0.1213
40 GLAUCOMA 1211 0.1156
41 FOREIGN BODY SENSATION IN EYES 383 0.1154
42 PENILE HAEMORRHAGE 60 0.1126
43 HYPHAEMA 32 0.1092
44 REACTION TO PRESERVATIVES 46 0.1075
45 BLEPHARITIS 179 0.1074
46 FOETAL HEART RATE DECELERATION 24 0.1013
47 PUNCTATE KERATITIS 42 0.0966
48 EYELID DISORDER 117 0.0888
49 PAINFUL ERECTION 42 0.0850
50 CHOROIDAL EFFUSION 28 0.0846
51 PENILE PAIN 186 0.0830
52 EYE DISCHARGE 371 0.0808
53 CORNEAL DISORDER 100 0.0806
54 EYE BURNS 39 0.0786
55 SWELLING OF EYELID 27 0.0730
56 OCULAR DISCOMFORT 240 0.0728
57 URETHRAL HAEMORRHAGE 28 0.0720
58 RED BLOOD CELLS URINE POSITIVE 35 0.0682
59 SUPERFICIAL INJURY OF EYE 32 0.0643
60 OCULAR HYPERTENSION 49 0.0633
61 EYELID OEDEMA 569 0.0624
62 EYE PAIN 1582 0.0622
63 ABNORMAL SENSATION IN EYE 181 0.0619
64 CONJUNCTIVITIS ALLERGIC 31 0.0618
65 CORNEAL OEDEMA 70 0.0593
66 CONJUNCTIVAL HYPERAEMIA 105 0.0571
67 HORDEOLUM 73 0.0564
68 OPTIC NERVE INJURY 33 0.0547
69 CYSTOID MACULAR OEDEMA 44 0.0529
70 EYE OPERATION 86 0.0526
71 CATARACT OPERATION 194 0.0523
72 INCISION SITE PAIN 41 0.0522
73 PRODUCT CONTAINER SEAL ISSUE 21 0.0511
74 DRY EYE 893 0.0508
75 OCULAR VASCULAR DISORDER 30 0.0500
76 HAIR GROWTH ABNORMAL 209 0.0497
77 CATARACT 1359 0.0478
78 PRODUCT PACKAGING QUANTITY ISSUE 131 0.0464
79 CORNEAL OPACITY 32 0.0458
80 OPTIC NERVE DISORDER 48 0.0454
81 EYE DISORDER 704 0.0422
82 PRODUCT CONTAINER ISSUE 162 0.0420
83 ASTHENOPIA 125 0.0416
84 ERECTION INCREASED 142 0.0400
85 CORNEAL ABRASION 32 0.0399
86 LACRIMATION INCREASED 526 0.0389
87 EYE INFECTION 190 0.0385
88 VISUAL FIELD DEFECT 184 0.0381
89 IRIDOCYCLITIS 48 0.0375
90 KERATITIS 57 0.0369
91 BLINDNESS UNILATERAL 291 0.0365
92 COLITIS MICROSCOPIC 61 0.0358
93 ULCERATIVE KERATITIS 54 0.0355
94 EYE SWELLING 697 0.0351
95 VISUAL ACUITY REDUCED 944 0.0348
96 MACULAR OEDEMA 106 0.0330
97 EYE INJURY 42 0.0321
98 PREMATURE SEPARATION OF PLACENTA 32 0.0317
99 LIQUID PRODUCT PHYSICAL ISSUE 43 0.0315
100 EYE OEDEMA 45 0.0313
101 ASTIGMATISM 24 0.0305
102 MACULAR HOLE 24 0.0299
103 INSTILLATION SITE PAIN 56 0.0296
104 PENILE SWELLING 21 0.0292
105 PRIAPISM 64 0.0289
106 IRITIS 50 0.0289
107 ANGLE CLOSURE GLAUCOMA 43 0.0264
108 MACULAR DEGENERATION 152 0.0258
109 HYPERAEMIA 27 0.0255
110 TEMPORAL ARTERITIS 21 0.0255
111 PERIPHERAL VENOUS DISEASE 21 0.0254
112 PHOTOPHOBIA 235 0.0248
113 RETINAL VEIN OCCLUSION 41 0.0245
114 VITREOUS DETACHMENT 28 0.0241
115 RETINAL DETACHMENT 115 0.0227
116 INCORRECT STORAGE OF DRUG 39 0.0225
117 VITREOUS FLOATERS 100 0.0223
118 METAMORPHOPSIA 23 0.0219
119 FOETAL DISTRESS SYNDROME 29 0.0219
120 PENIS DISORDER 40 0.0218
121 BLEPHAROSPASM 54 0.0216
122 MACULOPATHY 27 0.0209
123 EYE HAEMORRHAGE 166 0.0209
124 VISION BLURRED 1532 0.0200
125 MYOPIA 26 0.0191
126 EXPIRED DRUG ADMINISTERED 92 0.0184
127 PUPILLARY REFLEX IMPAIRED 22 0.0181
128 PRODUCT PHYSICAL CONSISTENCY ISSUE 24 0.0174
129 PIGMENTATION DISORDER 53 0.0174
130 UVEITIS 81 0.0173
131 SYNOVITIS 72 0.0171
132 VISUAL IMPAIRMENT 947 0.0169
133 SKIN DISCOLOURATION 397 0.0165
134 EYELID PTOSIS 93 0.0165
135 PHOTOPSIA 62 0.0163
136 BLINDNESS TRANSIENT 67 0.0163
137 PRODUCT PACKAGING ISSUE 66 0.0162
138 PRODUCT ADMINISTRATION ERROR 28 0.0159
139 LABYRINTHITIS 27 0.0157
140 DRUG ADMINISTERED AT INAPPROPRIATE SITE 163 0.0154
141 PROTEIN URINE PRESENT 37 0.0148
142 HYPOACUSIS 236 0.0147
143 ESSENTIAL HYPERTENSION 22 0.0146
144 AORTIC ARTERIOSCLEROSIS 22 0.0146
145 AORTIC STENOSIS 31 0.0140
146 PROSTATIC DISORDER 26 0.0139
147 TESTICULAR PAIN 25 0.0137
148 PERIPHERAL ARTERIAL OCCLUSIVE DISEASE 33 0.0136
149 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 916 0.0134
150 WRONG TECHNIQUE IN DRUG USAGE PROCESS 492 0.0134
151 PRODUCT FORMULATION ISSUE 52 0.0134
152 CONJUNCTIVAL HAEMORRHAGE 31 0.0133
153 DEMENTIA ALZHEIMER'S TYPE 23 0.0131
154 HEARING IMPAIRED 79 0.0130
155 LYMPHOCYTE COUNT DECREASED 104 0.0129
156 BRONCHIECTASIS 32 0.0127
157 PRODUCT USE COMPLAINT 32 0.0126
158 PRODUCT ADMINISTERED AT INAPPROPRIATE SITE 23 0.0125
159 NEUTROPHIL COUNT INCREASED 74 0.0123
160 EXPIRED PRODUCT ADMINISTERED 202 0.0123
161 ORTHOPNOEA 24 0.0122
162 BENIGN PROSTATIC HYPERPLASIA 38 0.0118
163 HEART RATE ABNORMAL 29 0.0116
164 DUODENAL ULCER HAEMORRHAGE 22 0.0115
165 CAESAREAN SECTION 104 0.0115
166 THYROID DISORDER 90 0.0114
167 ONYCHOMYCOSIS 23 0.0114
168 HAEMORRHAGIC ANAEMIA 55 0.0114
169 ANGIOPATHY 42 0.0113
170 PERIORBITAL OEDEMA 34 0.0113
171 INTENTIONAL DOSE OMISSION 22 0.0112
172 INCORRECT DOSAGE ADMINISTERED 25 0.0112
173 RALES 35 0.0110
174 BLOOD CHOLESTEROL ABNORMAL 27 0.0109
175 PRODUCT LABEL ISSUE 32 0.0107
176 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 97 0.0106
177 PERIPHERAL VASCULAR DISORDER 40 0.0105
178 CAROTID ARTERY STENOSIS 27 0.0105
179 ENDOPHTHALMITIS 31 0.0103
180 POOR QUALITY DRUG ADMINISTERED 67 0.0102
181 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 735 0.0101
182 DRY THROAT 55 0.0101
183 PROSTATE CANCER 101 0.0100
184 RHINITIS ALLERGIC 22 0.0100
185 BLOOD UREA INCREASED 124 0.0099
186 PRODUCT DOSE OMISSION 206 0.0098
187 BLOOD PRESSURE ABNORMAL 83 0.0098
188 INCORRECT DOSE ADMINISTERED 771 0.0095
189 HAEMOGLOBIN ABNORMAL 27 0.0094
190 EXTRASYSTOLES 43 0.0093
191 VISUAL DISTURBANCE 57 0.0093
192 HAIR COLOUR CHANGES 67 0.0093
193 PROSTATIC SPECIFIC ANTIGEN INCREASED 68 0.0092
194 ERECTILE DYSFUNCTION 130 0.0092
195 DEAFNESS 118 0.0091
196 SKIN IRRITATION 111 0.0091
197 DRUG INEFFECTIVE 5574 0.0090
198 DIVERTICULITIS 128 0.0089
199 SINUS BRADYCARDIA 51 0.0088
200 HYPERLIPIDAEMIA 77 0.0088
201 THERAPEUTIC RESPONSE DECREASED 278 0.0088
202 ACCIDENTAL EXPOSURE TO PRODUCT 199 0.0087
203 APPLICATION SITE DISCOLOURATION 27 0.0087
204 SPINAL COLUMN STENOSIS 43 0.0086
205 INFARCTION 40 0.0085
206 MYOSITIS 38 0.0085
207 BLOOD SODIUM DECREASED 91 0.0085
208 INCORRECT PRODUCT STORAGE 112 0.0085
209 GROIN PAIN 44 0.0085
210 PRODUCT STORAGE ERROR 92 0.0083
211 PAROSMIA 35 0.0083
212 SEASONAL ALLERGY 41 0.0083
213 INCREASED UPPER AIRWAY SECRETION 34 0.0082
214 DYSGRAPHIA 31 0.0082
215 DIZZINESS POSTURAL 35 0.0082
216 HYPERSENSITIVITY 746 0.0081
217 HYPONATRAEMIA 258 0.0081
218 OSTEOPENIA 51 0.0081
219 RENAL FAILURE CHRONIC 64 0.0081
220 HAIR TEXTURE ABNORMAL 67 0.0081
221 GOITRE 21 0.0080
222 SCIATICA 57 0.0080
223 OSTEOARTHRITIS 176 0.0080
224 TRICUSPID VALVE INCOMPETENCE 40 0.0080
225 BUNDLE BRANCH BLOCK LEFT 22 0.0079
226 BLOOD ALBUMIN DECREASED 41 0.0079
227 HEART RATE IRREGULAR 109 0.0079
228 OCULAR ICTERUS 22 0.0079
229 HYPERKALAEMIA 154 0.0078
230 PRODUCT QUALITY ISSUE 776 0.0078
231 SINUS DISORDER 80 0.0078
232 HAIR DISORDER 43 0.0078
233 HALLUCINATION, VISUAL 81 0.0078
234 ATELECTASIS 51 0.0078
235 THERAPEUTIC AGENT TOXICITY 27 0.0078
236 INTERVERTEBRAL DISC DEGENERATION 46 0.0078
237 MITRAL VALVE INCOMPETENCE 58 0.0078
238 HEART RATE DECREASED 129 0.0077
239 ATRIAL FLUTTER 38 0.0077
240 BASAL CELL CARCINOMA 61 0.0077
241 WRIST FRACTURE 50 0.0076
242 CARDIAC PACEMAKER INSERTION 28 0.0076
243 ARRHYTHMIA 218 0.0076
244 UPPER LIMB FRACTURE 87 0.0076
245 SUBDURAL HAEMATOMA 68 0.0076
246 HYPERKERATOSIS 23 0.0075
247 VARICOSE VEIN 23 0.0075
248 MEDICATION RESIDUE PRESENT 36 0.0075
249 EMPHYSEMA 47 0.0075
250 SCAB 41 0.0075
251 UPPER-AIRWAY COUGH SYNDROME 27 0.0075
252 BRADYCARDIA 225 0.0075
253 ARTERIOSCLEROSIS CORONARY ARTERY 32 0.0075
254 GOUT 72 0.0075
255 BLOOD CHOLESTEROL INCREASED 203 0.0075
256 IRON DEFICIENCY ANAEMIA 40 0.0074
257 NASAL DISCOMFORT 36 0.0074
258 VIRAL UPPER RESPIRATORY TRACT INFECTION 27 0.0074
259 MYDRIASIS 54 0.0074
260 HYPERAESTHESIA 39 0.0074
261 WALKING AID USER 26 0.0074
262 DERMATITIS 62 0.0074
263 UPPER GASTROINTESTINAL HAEMORRHAGE 74 0.0073
264 NOCTURIA 43 0.0072
265 HIATUS HERNIA 63 0.0072
266 PROTHROMBIN TIME PROLONGED 35 0.0072
267 DEMENTIA 86 0.0072
268 DYSPHONIA 217 0.0071
269 ERYTHEMA 669 0.0071
270 CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR 81 0.0071
271 GAIT INABILITY 48 0.0071
272 LIMB INJURY 84 0.0071
273 OESOPHAGITIS 47 0.0070
274 SENSATION OF FOREIGN BODY 29 0.0070
275 BLOOD MAGNESIUM DECREASED 29 0.0070
276 CARDIAC VALVE DISEASE 25 0.0070
277 PHLEBITIS 24 0.0070
278 DEAFNESS UNILATERAL 22 0.0070
279 EXOSTOSIS 36 0.0070
280 SLEEP APNOEA SYNDROME 75 0.0070
281 FACIAL PAIN 34 0.0069
282 SKIN WARM 21 0.0069
283 TROPONIN INCREASED 23 0.0069
284 TRANSIENT ISCHAEMIC ATTACK 157 0.0069
285 PULMONARY CONGESTION 51 0.0069
286 SPINAL DISORDER 36 0.0068
287 BURNING SENSATION 280 0.0068
288 ACUTE RESPIRATORY FAILURE 60 0.0068
289 GLOMERULAR FILTRATION RATE DECREASED 32 0.0068
290 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 205 0.0068
291 C-REACTIVE PROTEIN INCREASED 110 0.0067
292 DRY MOUTH 303 0.0067
293 NASAL DRYNESS 23 0.0067
294 BLOOD PRESSURE FLUCTUATION 66 0.0066
295 HAEMORRHAGIC STROKE 34 0.0066
296 BACTERIAL INFECTION 60 0.0066
297 ORTHOSTATIC HYPOTENSION 61 0.0066
298 HAEMOGLOBIN DECREASED 394 0.0066
299 PERONEAL NERVE PALSY 23 0.0066
300 RED BLOOD CELL COUNT DECREASED 96 0.0065
301 BLOOD PRESSURE SYSTOLIC INCREASED 51 0.0065
302 EYE MOVEMENT DISORDER 27 0.0065
303 DRUG INTOLERANCE 235 0.0065
304 FALL 1178 0.0065
305 AGEUSIA 87 0.0065
306 SPINAL OSTEOARTHRITIS 35 0.0064
307 ATRIOVENTRICULAR BLOCK 28 0.0064
308 COAGULOPATHY 68 0.0064
309 WEIGHT FLUCTUATION 25 0.0064
310 BLADDER DISORDER 36 0.0063
311 FAILURE TO THRIVE 23 0.0063
312 BRONCHITIS 285 0.0063
313 TRANSFUSION 36 0.0063
314 SPUTUM DISCOLOURED 25 0.0063
315 HIP FRACTURE 108 0.0063
316 GANGRENE 25 0.0063
317 INTERNATIONAL NORMALISED RATIO INCREASED 147 0.0063
318 ESCHERICHIA INFECTION 25 0.0063
319 GLOSSODYNIA 56 0.0063
320 PULMONARY MASS 41 0.0062
321 THROAT IRRITATION 146 0.0062
322 WHEEZING 152 0.0062
323 WOUND 61 0.0062
324 ANGINA UNSTABLE 32 0.0062
325 EAR PAIN 63 0.0062
326 HAEMORRHAGE INTRACRANIAL 62 0.0062
327 DYSPNOEA EXERTIONAL 105 0.0062
328 GENERALISED OEDEMA 44 0.0062
329 GASTRITIS 98 0.0061
330 MOUTH HAEMORRHAGE 25 0.0061
331 PLATELET COUNT INCREASED 41 0.0061
332 BEDRIDDEN 46 0.0061
333 VITAMIN D DEFICIENCY 31 0.0061
334 BLOOD POTASSIUM DECREASED 104 0.0061
335 HEMIPLEGIA 32 0.0061
336 OSTEOPOROSIS 110 0.0061
337 BALANCE DISORDER 304 0.0061
338 HAEMATOCRIT DECREASED 81 0.0061
339 TOOTH INFECTION 39 0.0060
340 ACUTE PULMONARY OEDEMA 22 0.0060
341 CLOSTRIDIUM DIFFICILE COLITIS 35 0.0060
342 MUSCULOSKELETAL DISCOMFORT 54 0.0060
343 BURSITIS 33 0.0059
344 ORAL DISORDER 25 0.0059
345 HYPOKALAEMIA 146 0.0059
346 DYSGEUSIA 282 0.0059
347 SMALL INTESTINAL OBSTRUCTION 40 0.0059
348 MYOPATHY 29 0.0058
349 PHOTOSENSITIVITY REACTION 52 0.0058
350 ECCHYMOSIS 26 0.0058
351 ARTHRITIS 225 0.0058
352 POST PROCEDURAL COMPLICATION 71 0.0057
353 TINNITUS 151 0.0057
354 CANDIDIASIS 24 0.0057
355 HAEMATEMESIS 89 0.0057
356 VERTIGO 206 0.0057
357 FULL BLOOD COUNT DECREASED 50 0.0057
358 FAECAL INCONTINENCE 28 0.0057
359 EAR DISCOMFORT 30 0.0057
360 RHINORRHOEA 174 0.0057
361 ANOSMIA 48 0.0057
362 MALIGNANT MELANOMA 41 0.0056
363 TENDERNESS 33 0.0056
364 BLOOD PRESSURE INCREASED 450 0.0056
365 ORAL PAIN 71 0.0056
366 END STAGE RENAL DISEASE 39 0.0056
367 BACK DISORDER 50 0.0056
368 CARDIOMEGALY 51 0.0056
369 POLLAKIURIA 130 0.0056
370 GASTROINTESTINAL HAEMORRHAGE 336 0.0056
371 SKIN CANCER 38 0.0056
372 SECRETION DISCHARGE 28 0.0056
373 PRE-EXISTING CONDITION IMPROVED 25 0.0055
374 SPINAL FRACTURE 54 0.0055
375 HAEMORRHOIDS 66 0.0055
376 GINGIVAL PAIN 26 0.0055
377 SKIN EXFOLIATION 163 0.0055
378 CARDIAC DISORDER 296 0.0055
379 ROTATOR CUFF SYNDROME 43 0.0055
380 CARDIAC FAILURE CONGESTIVE 350 0.0055
381 GASTROENTERITIS 46 0.0055
382 ACCIDENT 31 0.0054
383 ARTHROPATHY 141 0.0054
384 SKIN FISSURES 29 0.0054
385 APPLICATION SITE PAIN 75 0.0054
386 HYPOALBUMINAEMIA 22 0.0054
387 BLOOD PRESSURE DECREASED 200 0.0054
388 ANGINA PECTORIS 102 0.0054
389 PRODUCT SUBSTITUTION ISSUE 164 0.0054
390 ACCIDENTAL EXPOSURE 23 0.0054
391 BACTERAEMIA 30 0.0054
392 PHARMACEUTICAL PRODUCT COMPLAINT 145 0.0054
393 LOWER LIMB FRACTURE 49 0.0054
394 ASTHMA 231 0.0054
395 RHINITIS 22 0.0054
396 SYNCOPE 312 0.0053
397 RIB FRACTURE 58 0.0053
398 ELECTROCARDIOGRAM ABNORMAL 26 0.0053
399 PELVIC FRACTURE 23 0.0053
400 PULMONARY OEDEMA 138 0.0053
401 WRONG DRUG ADMINISTERED 48 0.0053
402 MUSCLE DISORDER 28 0.0053
403 CARPAL TUNNEL SYNDROME 40 0.0053
404 HALLUCINATION 202 0.0053
405 CYST 34 0.0052
406 SWELLING FACE 191 0.0052
407 URINARY INCONTINENCE 92 0.0052
408 CORONARY ARTERY DISEASE 129 0.0052
409 CONFUSIONAL STATE 487 0.0052
410 JOINT DISLOCATION 29 0.0052
411 SUPRAVENTRICULAR TACHYCARDIA 31 0.0052
412 PLEURAL EFFUSION 186 0.0051
413 JOINT INJURY 57 0.0051
414 ACUTE KIDNEY INJURY 284 0.0051
415 PULMONARY HYPERTENSION 66 0.0051
416 HEAD INJURY 89 0.0051
417 LACERATION 49 0.0051
418 SUBARACHNOID HAEMORRHAGE 30 0.0051
419 CONSTIPATION 534 0.0051
420 DIALYSIS 47 0.0051
421 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 28 0.0051
422 SNEEZING 55 0.0051
423 CARDIAC MURMUR 32 0.0051
424 TUBULOINTERSTITIAL NEPHRITIS 45 0.0051
425 PRESYNCOPE 67 0.0051
426 HYPERCHOLESTEROLAEMIA 25 0.0051
427 BLOOD URINE PRESENT 58 0.0051
428 DIZZINESS 1418 0.0051
429 UNRESPONSIVE TO STIMULI 76 0.0050
430 BLOOD POTASSIUM INCREASED 49 0.0050
431 HICCUPS 23 0.0050
432 CARDIAC OPERATION 21 0.0050
433 HYPOMAGNESAEMIA 33 0.0050
434 LUNG INFILTRATION 34 0.0050
435 SKIN DISORDER 79 0.0050
436 URINARY TRACT INFECTION 428 0.0050
437 RENAL FAILURE ACUTE 219 0.0050
438 BLOOD CALCIUM DECREASED 32 0.0050
439 PRESCRIBED UNDERDOSE 39 0.0050
440 MUSCULAR WEAKNESS 327 0.0050
441 DENTAL CARIES 34 0.0050
442 INITIAL INSOMNIA 28 0.0049
443 HYPOPHAGIA 64 0.0049
444 CHEST DISCOMFORT 259 0.0049
445 OSTEOMYELITIS 57 0.0049
446 FAECES DISCOLOURED 63 0.0049
447 ANAEMIA 541 0.0049
448 INFLAMMATION 103 0.0049
449 DRY SKIN 187 0.0049
450 SWOLLEN TONGUE 94 0.0048
451 BLISTER 134 0.0048
452 HYPOGLYCAEMIA 147 0.0048
453 DRUG HYPERSENSITIVITY 493 0.0048
454 DYSURIA 104 0.0048
455 MUSCLE ATROPHY 32 0.0048
456 ASTHENIA 998 0.0048
457 CONTRAINDICATED PRODUCT ADMINISTERED 29 0.0048
458 ORAL CANDIDIASIS 32 0.0048
459 STENT PLACEMENT 25 0.0048
460 PALPITATIONS 318 0.0048
461 DRUG DISPENSING ERROR 74 0.0048
462 AORTIC ANEURYSM 25 0.0048
463 URINE OUTPUT DECREASED 27 0.0048
464 CEREBRAL HAEMORRHAGE 103 0.0048
465 DISCOMFORT 110 0.0048
466 HAEMATOMA 77 0.0047
467 GASTROOESOPHAGEAL REFLUX DISEASE 209 0.0047
468 DIABETES MELLITUS INADEQUATE CONTROL 46 0.0047
469 NERVOUSNESS 165 0.0047
470 OXYGEN SATURATION DECREASED 108 0.0047
471 SKIN ULCER 66 0.0047
472 ECZEMA 52 0.0047
473 BLOOD TEST ABNORMAL 26 0.0047
474 LIP SWELLING 88 0.0047
475 MICTURITION URGENCY 29 0.0047
476 MYOCARDIAL ISCHAEMIA 41 0.0047
477 CONTUSION 243 0.0047
478 MASS 36 0.0047
479 MELAENA 62 0.0047
480 RESTLESS LEGS SYNDROME 49 0.0047
481 POLYURIA 21 0.0047
482 OEDEMA PERIPHERAL 394 0.0047
483 LARYNGITIS 27 0.0046
484 METABOLIC ACIDOSIS 73 0.0046
485 RENAL TUBULAR NECROSIS 24 0.0046
486 CIRCULATORY COLLAPSE 52 0.0046
487 INCREASED TENDENCY TO BRUISE 26 0.0046
488 PRURITUS 747 0.0046
489 DELUSION 39 0.0046
490 BRONCHOSPASM 41 0.0046
491 BLOOD COUNT ABNORMAL 39 0.0046
492 NEUROPATHY PERIPHERAL 193 0.0046
493 DYSPNOEA 1385 0.0045
494 PNEUMOTHORAX 37 0.0045
495 BLOOD CREATININE INCREASED 174 0.0045
496 CELLULITIS 132 0.0045
497 PNEUMONIA 747 0.0045
498 ATAXIA 33 0.0045
499 BLOOD TESTOSTERONE DECREASED 24 0.0045
500 KNEE ARTHROPLASTY 40 0.0045
501 CARDIAC FAILURE 195 0.0045
502 MUSCLE TWITCHING 62 0.0045
503 SPINAL COMPRESSION FRACTURE 22 0.0045
504 HAEMOPTYSIS 73 0.0045
505 RESPIRATORY FAILURE 192 0.0045
506 DECUBITUS ULCER 22 0.0044
507 NEOPLASM MALIGNANT 115 0.0044
508 HYPOKINESIA 35 0.0044
509 ULCER 38 0.0044
510 ORAL DISCOMFORT 36 0.0044
511 DEHYDRATION 352 0.0044
512 THERAPEUTIC RESPONSE UNEXPECTED 116 0.0044
513 INTENTIONAL PRODUCT USE ISSUE 76 0.0044
514 HYPOTENSION 477 0.0044
515 PERIPHERAL SWELLING 265 0.0044
516 DEVICE MALFUNCTION 101 0.0044
517 ECONOMIC PROBLEM 46 0.0044
518 SPEECH DISORDER 134 0.0044
519 URINARY RETENTION 80 0.0044
520 MENTAL STATUS CHANGES 77 0.0043
521 LEUKOCYTOSIS 45 0.0043
522 RASH MACULAR 67 0.0043
523 SQUAMOUS CELL CARCINOMA 22 0.0043
524 CEREBROVASCULAR ACCIDENT 479 0.0043
525 NECK PAIN 132 0.0043
526 ASPIRATION 26 0.0043
527 GAIT DISTURBANCE 467 0.0043
528 PRODUCT PHYSICAL ISSUE 39 0.0043
529 TOOTH FRACTURE 26 0.0043
530 WEIGHT DECREASED 626 0.0043
531 PULMONARY FIBROSIS 40 0.0043
532 RENAL DISORDER 103 0.0043
533 BLOOD ALKALINE PHOSPHATASE INCREASED 75 0.0042
534 KIDNEY INFECTION 40 0.0042
535 MYALGIA 423 0.0042
536 SPLENOMEGALY 28 0.0042
537 OEDEMA 131 0.0042
538 DECREASED APPETITE 483 0.0042
539 PSYCHOLOGICAL TRAUMA 22 0.0042
540 RECTAL HAEMORRHAGE 112 0.0042
541 BLOOD CALCIUM INCREASED 23 0.0042
542 TACHYPNOEA 28 0.0042
543 FOOT FRACTURE 44 0.0042
544 OROPHARYNGEAL PAIN 196 0.0042
545 FOOT DEFORMITY 23 0.0042
546 INCONTINENCE 26 0.0042
547 TENDON RUPTURE 34 0.0042
548 SLUGGISHNESS 24 0.0042
549 RENAL FAILURE 322 0.0042
550 CEREBRAL INFARCTION 64 0.0042
551 CYSTITIS 76 0.0042
552 HERPES ZOSTER 123 0.0042
553 LUNG DISORDER 102 0.0042
554 DRUG INTERACTION 370 0.0042
555 THROMBOSIS 182 0.0042
556 CHEST PAIN 477 0.0041
557 DYSARTHRIA 95 0.0041
558 APHONIA 28 0.0041
559 MULTIPLE INJURIES 24 0.0041
560 HAEMODIALYSIS 31 0.0041
561 PLATELET COUNT DECREASED 220 0.0041
562 MIDDLE INSOMNIA 42 0.0041
563 MEMORY IMPAIRMENT 299 0.0041
564 THIRST 37 0.0041
565 FLUID RETENTION 116 0.0041
566 HEADACHE 1386 0.0040
567 DEFORMITY 23 0.0040
568 VENTRICULAR TACHYCARDIA 40 0.0040
569 MUSCULOSKELETAL PAIN 155 0.0040
570 COLON CANCER 29 0.0040
571 PETECHIAE 24 0.0040
572 DRUG EFFECT DECREASED 225 0.0040
573 ELECTROLYTE IMBALANCE 23 0.0040
574 PURPURA 22 0.0040
575 MULTIPLE MYELOMA 21 0.0040
576 LOCALISED INFECTION 48 0.0040
577 FEEDING DISORDER 27 0.0040
578 SWELLING 174 0.0040
579 CANDIDA INFECTION 26 0.0040
580 NEURALGIA 46 0.0040
581 FUNGAL INFECTION 69 0.0040
582 NEPHROLITHIASIS 87 0.0040
583 DYSSTASIA 65 0.0040
584 GINGIVAL BLEEDING 29 0.0040
585 PNEUMONIA ASPIRATION 53 0.0040
586 UPPER RESPIRATORY TRACT INFECTION 99 0.0040
587 INTERNAL HAEMORRHAGE 25 0.0039
588 DRUG EXPOSURE DURING PREGNANCY 138 0.0039
589 HIP ARTHROPLASTY 25 0.0039
590 DISORIENTATION 102 0.0039
591 MUSCLE TIGHTNESS 38 0.0039
592 FATIGUE 1500 0.0039
593 APPLICATION SITE ERYTHEMA 76 0.0039
594 HYPOXIA 69 0.0039
595 SINUS TACHYCARDIA 33 0.0039
596 HEART RATE INCREASED 209 0.0039
597 MUSCULOSKELETAL DISORDER 42 0.0039
598 HYPERSOMNIA 59 0.0039
599 INTENTIONAL PRODUCT MISUSE 169 0.0039
600 IMPAIRED DRIVING ABILITY 29 0.0039
601 JOINT RANGE OF MOTION DECREASED 22 0.0039
602 RESPIRATORY DISORDER 63 0.0039
603 MEDICATION ERROR 139 0.0038
604 TOOTH DISORDER 50 0.0038
605 HYPOTONIA 25 0.0038
606 FRACTURE 33 0.0038
607 INFLUENZA 203 0.0038
608 INSOMNIA 605 0.0038
609 SKIN LESION 51 0.0038
610 FLUID OVERLOAD 47 0.0038
611 INTERVERTEBRAL DISC PROTRUSION 51 0.0038
612 RESPIRATORY TRACT CONGESTION 33 0.0038
613 HOT FLUSH 138 0.0038
614 FLATULENCE 117 0.0038
615 DISABILITY 25 0.0038
616 LIMB DISCOMFORT 55 0.0038
617 HAEMATOCHEZIA 91 0.0038
618 HEPATIC ENZYME INCREASED 120 0.0038
619 CHOLELITHIASIS 80 0.0038
620 AMNESIA 154 0.0038
621 PNEUMONITIS 44 0.0038
622 RASH ERYTHEMATOUS 80 0.0037
623 FEMUR FRACTURE 79 0.0037
624 STOMATITIS 110 0.0037
625 MALAISE 948 0.0037
626 TOOTH EXTRACTION 29 0.0037
627 DISEASE RECURRENCE 45 0.0037
628 SOMNOLENCE 415 0.0037
629 SINUS CONGESTION 29 0.0037
630 NIGHTMARE 82 0.0037
631 DYSPHAGIA 194 0.0037
632 TREMOR 370 0.0037
633 PLASMA CELL MYELOMA 60 0.0037
634 LYMPHOMA 29 0.0037
635 BACK PAIN 479 0.0037
636 EJECTION FRACTION DECREASED 28 0.0037
637 PERICARDIAL EFFUSION 45 0.0037
638 APPLICATION SITE IRRITATION 30 0.0037
639 PAIN IN EXTREMITY 628 0.0037
640 NASOPHARYNGITIS 336 0.0037
641 APHASIA 65 0.0037
642 VASCULITIS 23 0.0037
643 PARANOIA 41 0.0037
644 DYSPEPSIA 197 0.0037
645 ISCHAEMIC STROKE 39 0.0037
646 ABASIA 91 0.0036
647 ABSCESS 30 0.0036
648 ABDOMINAL DISCOMFORT 281 0.0036
649 TACHYCARDIA 175 0.0036
650 MYELODYSPLASTIC SYNDROME 32 0.0036
651 PROCEDURAL COMPLICATION 21 0.0036
652 BONE DISORDER 45 0.0036
653 SENSORY DISTURBANCE 39 0.0036
654 HYPERGLYCAEMIA 76 0.0036
655 HYPOAESTHESIA 307 0.0036
656 PROTEINURIA 31 0.0036
657 JOINT SWELLING 190 0.0036
658 NERVE INJURY 22 0.0036
659 PARALYSIS 30 0.0036
660 WHITE BLOOD CELL COUNT DECREASED 188 0.0036
661 RENAL IMPAIRMENT 137 0.0036
662 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 73 0.0036
663 BLOOD BILIRUBIN INCREASED 62 0.0035
664 SURGERY 86 0.0035
665 LOSS OF CONSCIOUSNESS 267 0.0035
666 GENERAL PHYSICAL HEALTH DETERIORATION 178 0.0035
667 INTESTINAL OBSTRUCTION 64 0.0035
668 MEDICAL DEVICE COMPLICATION 26 0.0035
669 TOXIC EPIDERMAL NECROLYSIS 29 0.0035
670 VIRAL INFECTION 60 0.0035
671 CARDIOMYOPATHY 32 0.0035
672 SCAR 33 0.0035
673 OBESITY 29 0.0034
674 MUSCULOSKELETAL STIFFNESS 148 0.0034
675 PERIPHERAL COLDNESS 27 0.0034
676 MUSCLE SPASMS 365 0.0034
677 RASH 690 0.0034
678 LYMPHOPENIA 22 0.0034
679 CHROMATURIA 47 0.0034
680 GASTRIC ULCER 40 0.0034
681 RESPIRATORY DISTRESS 56 0.0034
682 DRUG EFFECT INCOMPLETE 131 0.0034
683 DEEP VEIN THROMBOSIS 157 0.0034
684 ARTHRALGIA 662 0.0034
685 CHRONIC KIDNEY DISEASE 101 0.0034
686 DYSKINESIA 80 0.0034
687 PHARYNGITIS 24 0.0034
688 IRRITABLE BOWEL SYNDROME 33 0.0034
689 GALLBLADDER DISORDER 41 0.0034
690 LABORATORY TEST ABNORMAL 52 0.0034
691 ROAD TRAFFIC ACCIDENT 81 0.0034
692 LOCAL SWELLING 59 0.0034
693 EATING DISORDER 39 0.0033
694 FREQUENT BOWEL MOVEMENTS 35 0.0033
695 PARAESTHESIA 309 0.0033
696 THERAPY NON-RESPONDER 39 0.0033
697 FEELING ABNORMAL 470 0.0033
698 GASTRIC DISORDER 73 0.0033
699 ABNORMAL DREAMS 68 0.0033
700 MOVEMENT DISORDER 62 0.0033
701 NO THERAPEUTIC RESPONSE 41 0.0033
702 PRODUCT USE ISSUE 272 0.0033
703 PANCYTOPENIA 99 0.0033
704 PAIN 942 0.0033
705 PROCEDURAL PAIN 46 0.0033
706 METASTASES TO BONE 23 0.0033
707 CLOSTRIDIUM DIFFICILE INFECTION 30 0.0032
708 CHILLS 210 0.0032
709 OFF LABEL USE 849 0.0032
710 DISEASE PROGRESSION 175 0.0032
711 SEPSIS 199 0.0032
712 UNEVALUABLE EVENT 140 0.0032
713 BONE PAIN 106 0.0032
714 RHABDOMYOLYSIS 80 0.0032
715 ABDOMINAL PAIN UPPER 343 0.0032
716 CHOKING 32 0.0032
717 ALANINE AMINOTRANSFERASE INCREASED 121 0.0032
718 TOOTHACHE 32 0.0032
719 RASH PRURITIC 87 0.0031
720 BLOOD GLUCOSE INCREASED 374 0.0031
721 STRESS 110 0.0031
722 RENAL INJURY 35 0.0031
723 RASH GENERALISED 78 0.0031
724 FIBROMYALGIA 36 0.0031
725 ASPARTATE AMINOTRANSFERASE INCREASED 105 0.0031
726 INTERSTITIAL LUNG DISEASE 73 0.0031
727 FACE OEDEMA 32 0.0031
728 MOUTH ULCERATION 33 0.0031
729 MENTAL DISORDER 69 0.0031
730 HEPATIC STEATOSIS 32 0.0031
731 HYPOAESTHESIA ORAL 27 0.0030
732 THERAPY CESSATION 55 0.0030
733 THINKING ABNORMAL 37 0.0030
734 PARAESTHESIA ORAL 23 0.0030
735 ACTIVITIES OF DAILY LIVING IMPAIRED 61 0.0030
736 HEPATIC FUNCTION ABNORMAL 57 0.0030
737 FEELING HOT 105 0.0030
738 THROMBOCYTOPENIA 177 0.0030
739 FEAR 59 0.0030
740 EAR INFECTION 36 0.0030
741 INJURY ASSOCIATED WITH DEVICE 21 0.0030
742 THROAT TIGHTNESS 46 0.0030
743 LACTIC ACIDOSIS 43 0.0030
744 SHOCK 38 0.0030
745 LIVER FUNCTION TEST ABNORMAL 66 0.0030
746 NEUTROPHIL COUNT DECREASED 53 0.0030
747 DELIRIUM 53 0.0030
748 EXTRA DOSE ADMINISTERED 35 0.0030
749 MOBILITY DECREASED 105 0.0030
750 ASCITES 50 0.0029
751 BLADDER CANCER 38 0.0029
752 COGNITIVE DISORDER 71 0.0029
753 PALLOR 42 0.0029
754 POOR QUALITY SLEEP 31 0.0029
755 ALOPECIA 299 0.0029
756 PRODUCT USE IN UNAPPROVED INDICATION 147 0.0029
757 WEIGHT INCREASED 340 0.0029
758 COLITIS 47 0.0029
759 DEPRESSED LEVEL OF CONSCIOUSNESS 62 0.0029
760 OSTEONECROSIS OF JAW 50 0.0029
761 MYOCARDIAL INFARCTION 378 0.0028
762 NO ADVERSE EVENT 183 0.0028
763 PYREXIA 528 0.0028
764 PAIN OF SKIN 24 0.0028
765 GASTROINTESTINAL DISORDER 100 0.0028
766 GASTRIC HAEMORRHAGE 21 0.0028
767 BODY TEMPERATURE INCREASED 32 0.0028
768 NAUSEA 1195 0.0028
769 HYPERHIDROSIS 214 0.0028
770 NEOPLASM PROGRESSION 36 0.0028
771 STAPHYLOCOCCAL INFECTION 58 0.0028
772 BLOOD GLUCOSE DECREASED 87 0.0027
773 HYPOCALCAEMIA 27 0.0027
774 VOMITING 696 0.0027
775 RASH PAPULAR 32 0.0027
776 ANHEDONIA 32 0.0027
777 CARDIAC ARREST 139 0.0027
778 FLUSHING 177 0.0026
779 TYPE 2 DIABETES MELLITUS 57 0.0026
780 ABDOMINAL PAIN 328 0.0026
781 DRUG TOXICITY 36 0.0026
782 ILL-DEFINED DISORDER 48 0.0025
783 ELECTROCARDIOGRAM QT PROLONGED 45 0.0025
784 INFECTION 167 0.0025
785 ALTERED STATE OF CONSCIOUSNESS 27 0.0025
786 LYMPHADENOPATHY 48 0.0025
787 CYANOSIS 25 0.0025
788 ACCIDENTAL OVERDOSE 48 0.0025
789 MIGRAINE 112 0.0025
790 COLD SWEAT 26 0.0025
791 RESTLESSNESS 53 0.0024
792 AGITATION 117 0.0024
793 SEIZURE 103 0.0024
794 COMA 66 0.0024
795 HALLUCINATION, AUDITORY 22 0.0024
796 ANOREXIA 33 0.0024
797 ANGIOEDEMA 58 0.0024
798 RHEUMATOID ARTHRITIS 116 0.0024
799 FEBRILE NEUTROPENIA 73 0.0024
800 PULMONARY EMBOLISM 148 0.0024
801 COORDINATION ABNORMAL 24 0.0024
802 CARDIO-RESPIRATORY ARREST 67 0.0023
803 EPILEPSY 35 0.0023
804 UNDERDOSE 85 0.0023
805 JAUNDICE 42 0.0023
806 DRUG-INDUCED LIVER INJURY 23 0.0023
807 ENCEPHALOPATHY 29 0.0023
808 ABNORMAL BEHAVIOUR 67 0.0022
809 PREGNANCY 35 0.0022
810 GASTROENTERITIS VIRAL 21 0.0022
811 MULTI-ORGAN FAILURE 40 0.0022
812 INJURY 109 0.0022
813 LEUKOPENIA 58 0.0022
814 CHOLESTASIS 21 0.0022
815 EMOTIONAL DISTRESS 79 0.0022
816 RASH MACULO-PAPULAR 24 0.0022
817 PANCREATITIS 71 0.0021
818 SEPTIC SHOCK 47 0.0021
819 SYSTEMIC LUPUS ERYTHEMATOSUS 24 0.0021
820 RETCHING 25 0.0021
821 INTENTIONAL DRUG MISUSE 45 0.0021
822 NEUTROPENIA 120 0.0021
823 INFLUENZA LIKE ILLNESS 114 0.0021
824 PANIC ATTACK 45 0.0021
825 MULTIPLE SCLEROSIS 55 0.0021
826 ADVERSE DRUG REACTION 72 0.0021
827 HEPATITIS 29 0.0020
828 ANAPHYLACTIC SHOCK 27 0.0020
829 DEPRESSED MOOD 54 0.0020
830 DISTURBANCE IN ATTENTION 65 0.0020
831 STEVENS-JOHNSON SYNDROME 30 0.0020
832 MALIGNANT NEOPLASM PROGRESSION 87 0.0020
833 AGGRESSION 65 0.0019
834 URTICARIA 163 0.0019
835 ABDOMINAL PAIN LOWER 29 0.0019
836 PSYCHOMOTOR HYPERACTIVITY 21 0.0019
837 CRYING 47 0.0019
838 MOOD SWINGS 40 0.0019
839 CARDIOVASCULAR DISORDER 38 0.0019
840 PREMATURE BABY 31 0.0019
841 BONE MARROW FAILURE 26 0.0019
842 HEPATIC FAILURE 35 0.0018
843 ADVERSE EVENT 97 0.0018
844 RESPIRATORY ARREST 38 0.0018
845 SUICIDAL IDEATION 102 0.0018
846 EMOTIONAL DISORDER 38 0.0018
847 MOOD ALTERED 29 0.0018
848 LIVER DISORDER 41 0.0017
849 NERVOUS SYSTEM DISORDER 38 0.0017
850 IRRITABILITY 65 0.0016
851 CONVULSION 91 0.0016
852 INCORRECT DRUG ADMINISTRATION DURATION 44 0.0016
853 INJECTION SITE MASS 25 0.0015
854 INFUSION RELATED REACTION 37 0.0015
855 PERITONITIS 21 0.0015
856 COLITIS ULCERATIVE 21 0.0015
857 INJECTION SITE BRUISING 63 0.0014
858 VAGINAL HAEMORRHAGE 40 0.0014
859 HOSPITALISATION 82 0.0014
860 INJECTION SITE PAIN 213 0.0014
861 DEVICE ISSUE 35 0.0013
862 PSORIASIS 82 0.0013
863 PSYCHOTIC DISORDER 24 0.0013
864 MULTIPLE SCLEROSIS RELAPSE 56 0.0013
865 MATERNAL EXPOSURE DURING PREGNANCY 34 0.0013
866 INCORRECT ROUTE OF DRUG ADMINISTRATION 41 0.0011
867 TOXICITY TO VARIOUS AGENTS 87 0.0011
868 WITHDRAWAL SYNDROME 21 0.0011
869 INJECTION SITE PRURITUS 42 0.0011
870 TARDIVE DYSKINESIA 23 0.0010
871 INJECTION SITE SWELLING 41 0.0010
872 GYNAECOMASTIA 24 0.0010
873 FOETAL EXPOSURE DURING PREGNANCY 35 0.0010
874 DRUG DEPENDENCE 23 0.0009
875 INJECTION SITE ERYTHEMA 72 0.0009
876 DRUG WITHDRAWAL SYNDROME 35 0.0008
877 EXPOSURE DURING PREGNANCY 21 0.0007
878 SUICIDE ATTEMPT 21 0.0006