Proton Pump Inhibitor [EPC]

Proton Pump Inhibitor [EPC] was reported 448116 times

Drugs of the Proton Pump Inhibitor [EPC] class are most commonly taken among patients reporting these side effects:

# Drug class Count Frequency
0 RENAL HAEMANGIOMA 791 0.9937
1 HYPERTENSIVE NEPHROPATHY 681 0.6886
2 REBOUND ACID HYPERSECRETION 1993 0.6814
3 CHRONIC KIDNEY DISEASE-MINERAL AND BONE DISORDER 639 0.6698
4 END STAGE RENAL DISEASE 10569 0.6567
5 NEPHROGENIC ANAEMIA 2580 0.6017
6 CHRONIC KIDNEY DISEASE 36990 0.5509
7 HYPERPARATHYROIDISM SECONDARY 1106 0.4883
8 HYPERCHLORHYDRIA 2167 0.4077
9 TUBULOINTERSTITIAL NEPHRITIS 5274 0.3754
10 RENAL INJURY 10126 0.3682
11 DIABETIC NEPHROPATHY 704 0.3636
12 SUBACUTE CUTANEOUS LUPUS ERYTHEMATOSUS 434 0.3420
13 NEPHROSCLEROSIS 330 0.3287
14 SEDATION COMPLICATION 444 0.2830
15 HYPOMAGNESAEMIA 2586 0.2641
16 REBOUND EFFECT 1652 0.2626
17 ACUTE KIDNEY INJURY 24801 0.2281
18 NEPHROPATHY 1636 0.2100
19 GASTRIC POLYPS 324 0.1798
20 CREATININE RENAL CLEARANCE DECREASED 596 0.1723
21 RENAL FAILURE 18125 0.1592
22 TENOSYNOVITIS 344 0.1543
23 COLITIS MICROSCOPIC 467 0.1538
24 NEUTROPENIC SEPSIS 875 0.1518
25 RENAL CYST 948 0.1461
26 RHEUMATOID NODULE 316 0.1363
27 HYPOCALCAEMIA 1907 0.1339
28 DIALYSIS 1545 0.1319
29 INFECTIVE PULMONARY EXACERBATION OF CYSTIC FIBROSIS 617 0.1313
30 GASTROOESOPHAGEAL REFLUX DISEASE 7929 0.1304
31 RHINITIS ALLERGIC 406 0.1295
32 HYPONATRAEMIA 5532 0.1249
33 HIATUS HERNIA 1296 0.1211
34 ORTHOSTATIC HYPOTENSION 1583 0.1156
35 C-REACTIVE PROTEIN ABNORMAL 404 0.1155
36 BLOOD CALCIUM DECREASED 1028 0.1134
37 AZOTAEMIA 340 0.1132
38 IRON DEFICIENCY ANAEMIA 783 0.1109
39 OESOPHAGITIS 931 0.1084
40 CREPITATIONS 275 0.1075
41 EPIGASTRIC DISCOMFORT 329 0.1065
42 BLOOD MAGNESIUM DECREASED 657 0.1050
43 DUODENAL ULCER PERFORATION 313 0.1042
44 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 786 0.1038
45 HELICOBACTER INFECTION 551 0.1031
46 VITAMIN B12 DEFICIENCY 289 0.1019
47 HEPATIC CYTOLYSIS 289 0.1013
48 GASTRITIS 2099 0.1009
49 RENAL TUBULAR NECROSIS 758 0.1005
50 ABNORMAL LOSS OF WEIGHT 533 0.1003
51 SPINAL OSTEOARTHRITIS 691 0.0974
52 VITAMIN D DEFICIENCY 699 0.0949
53 HYPOKALAEMIA 3264 0.0941
54 LOWER RESPIRATORY TRACT INFECTION 2911 0.0941
55 RALES 430 0.0941
56 PROTEINURIA 1197 0.0904
57 OESOPHAGEAL ULCER 284 0.0890
58 NOCTURIA 773 0.0888
59 BURSITIS 690 0.0888
60 UPPER GASTROINTESTINAL HAEMORRHAGE 1207 0.0873
61 ATELECTASIS 691 0.0865
62 HYPERKALAEMIA 2309 0.0858
63 INTERVERTEBRAL DISC DEGENERATION 672 0.0858
64 CHOLECYSTITIS CHRONIC 557 0.0856
65 BRONCHIECTASIS 381 0.0855
66 ABDOMINAL TENDERNESS 339 0.0852
67 SLEEP APNOEA SYNDROME 1330 0.0848
68 CHOLESTASIS 1205 0.0845
69 GASTRITIS EROSIVE 332 0.0844
70 HYPOPHOSPHATAEMIA 446 0.0832
71 HAEMATEMESIS 1708 0.0831
72 BLOOD PRESSURE DIASTOLIC DECREASED 459 0.0829
73 HYDRONEPHROSIS 478 0.0829
74 RENAL IMPAIRMENT 5098 0.0824
75 CLOSTRIDIUM DIFFICILE COLITIS 659 0.0815
76 DIVERTICULUM 531 0.0813
77 BREATH SOUNDS ABNORMAL 282 0.0809
78 BLOOD ALBUMIN DECREASED 509 0.0809
79 HEPATITIS CHOLESTATIC 369 0.0808
80 GASTROINTESTINAL MOTILITY DISORDER 308 0.0806
81 TOXIC EPIDERMAL NECROLYSIS 906 0.0804
82 PANCREATITIS ACUTE 1353 0.0803
83 MELAENA 1437 0.0801
84 NEUTROPHIL COUNT INCREASED 642 0.0798
85 LABELLED DRUG-DRUG INTERACTION MEDICATION ERROR 597 0.0798
86 ODYNOPHAGIA 345 0.0798
87 DRUG INTERACTION 9901 0.0793
88 OSTEOPENIA 959 0.0786
89 PYELONEPHRITIS 511 0.0786
90 FAECALOMA 314 0.0785
91 RENAL FAILURE ACUTE 3336 0.0785
92 HEPATIC ENCEPHALOPATHY 585 0.0783
93 CARPAL TUNNEL SYNDROME 841 0.0781
94 POLYURIA 491 0.0779
95 PULMONARY FUNCTION TEST DECREASED 276 0.0776
96 OSTEOARTHRITIS 2435 0.0769
97 INTESTINAL ISCHAEMIA 325 0.0767
98 ULCER 947 0.0766
99 IMPAIRED GASTRIC EMPTYING 440 0.0766
100 URINE OUTPUT DECREASED 552 0.0763
101 LIVER FUNCTION TEST ABNORMAL 1951 0.0761
102 SENSORY LOSS 488 0.0760
103 PRE-EXISTING CONDITION IMPROVED 426 0.0754
104 HYPERLIPIDAEMIA 759 0.0753
105 LEFT VENTRICULAR DYSFUNCTION 385 0.0750
106 FIBROMYALGIA 1280 0.0750
107 BLOOD SODIUM DECREASED 1090 0.0748
108 INTERNATIONAL NORMALISED RATIO INCREASED 1979 0.0746
109 SPUTUM DISCOLOURED 512 0.0746
110 BLOOD PRESSURE SYSTOLIC INCREASED 1066 0.0746
111 DIABETIC NEUROPATHY 319 0.0743
112 HUMERUS FRACTURE 288 0.0742
113 ATRIOVENTRICULAR BLOCK FIRST DEGREE 276 0.0737
114 ELECTROLYTE IMBALANCE 611 0.0733
115 HAEMODIALYSIS 588 0.0731
116 MUSCLE INJURY 309 0.0729
117 ORAL CANDIDIASIS 685 0.0726
118 MITRAL VALVE INCOMPETENCE 660 0.0725
119 CYSTIC FIBROSIS 328 0.0724
120 CHOLANGITIS 308 0.0723
121 GASTRIC ULCER 1116 0.0722
122 GASTROENTERITIS 813 0.0721
123 POLYP 364 0.0718
124 HAEMATURIA 2025 0.0716
125 TONGUE DISORDER 444 0.0715
126 UROSEPSIS 498 0.0714
127 PATHOLOGICAL FRACTURE 284 0.0713
128 CHOLECYSTITIS 658 0.0713
129 ARTERIOSCLEROSIS CORONARY ARTERY 369 0.0711
130 INCORRECT PRODUCT ADMINISTRATION DURATION 929 0.0707
131 BLOOD UREA INCREASED 1006 0.0704
132 PULMONARY FIBROSIS 945 0.0704
133 HEPATITIS ACUTE 355 0.0703
134 CARDIOMEGALY 757 0.0703
135 ACUTE RESPIRATORY FAILURE 966 0.0702
136 ADRENAL INSUFFICIENCY 515 0.0700
137 FOLLICULITIS 335 0.0699
138 MALNUTRITION 567 0.0695
139 CLOSTRIDIUM DIFFICILE INFECTION 1061 0.0695
140 HEPATIC STEATOSIS 980 0.0691
141 RHINITIS 416 0.0690
142 COLITIS ISCHAEMIC 358 0.0690
143 CHOLECYSTITIS ACUTE 312 0.0689
144 EXOSTOSIS 469 0.0689
145 ATRIAL FLUTTER 449 0.0687
146 DUODENAL ULCER 386 0.0684
147 TRICUSPID VALVE INCOMPETENCE 408 0.0679
148 MOUTH ULCERATION 1040 0.0677
149 DYSPEPSIA 4960 0.0676
150 EOSINOPHILIA 871 0.0675
151 RED BLOOD CELL SEDIMENTATION RATE INCREASED 562 0.0674
152 HAEMORRHAGIC ANAEMIA 297 0.0674
153 ELECTROCARDIOGRAM QT PROLONGED 1818 0.0674
154 HYPERCALCAEMIA 637 0.0673
155 HEPATOCELLULAR INJURY 842 0.0673
156 SKIN NECROSIS 289 0.0672
157 AGRANULOCYTOSIS 856 0.0672
158 FAECES DISCOLOURED 1157 0.0671
159 HYPOALBUMINAEMIA 372 0.0671
160 DYSURIA 1972 0.0670
161 RENAL FAILURE CHRONIC 516 0.0670
162 DYSPNOEA EXERTIONAL 1802 0.0670
163 SUPRAVENTRICULAR TACHYCARDIA 515 0.0669
164 TOXIC SKIN ERUPTION 520 0.0669
165 C-REACTIVE PROTEIN INCREASED 1741 0.0667
166 TROPONIN INCREASED 337 0.0666
167 KIDNEY INFECTION 971 0.0663
168 NEPHROLITHIASIS 2200 0.0662
169 HYPERCHOLESTEROLAEMIA 417 0.0662
170 SMALL INTESTINAL OBSTRUCTION 615 0.0662
171 HYPOVOLAEMIA 306 0.0662
172 IRRITABLE BOWEL SYNDROME 963 0.0660
173 SEROTONIN SYNDROME 910 0.0659
174 JOINT EFFUSION 363 0.0658
175 MYOSITIS 414 0.0657
176 BLOOD ALKALINE PHOSPHATASE INCREASED 1371 0.0656
177 OLIGURIA 326 0.0655
178 TENDONITIS 822 0.0650
179 CHOLELITHIASIS 1691 0.0649
180 RECTAL HAEMORRHAGE 2229 0.0648
181 WHEEZING 2644 0.0647
182 HEMIPLEGIA 441 0.0647
183 OSTEOPOROSIS 2114 0.0647
184 MYOCARDIAL ISCHAEMIA 650 0.0646
185 RHABDOMYOLYSIS 2099 0.0644
186 CIRCULATORY COLLAPSE 913 0.0641
187 SCOLIOSIS 312 0.0640
188 ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS 381 0.0639
189 SPLENOMEGALY 586 0.0637
190 ATRIOVENTRICULAR BLOCK COMPLETE 328 0.0634
191 NEPHROTIC SYNDROME 330 0.0634
192 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 2592 0.0633
193 ACUTE CORONARY SYNDROME 441 0.0631
194 ASPIRATION 507 0.0631
195 HAEMATOCRIT DECREASED 1051 0.0630
196 BLOOD POTASSIUM DECREASED 1474 0.0630
197 BLOOD IRON DECREASED 497 0.0630
198 OBSTRUCTIVE AIRWAYS DISORDER 533 0.0628
199 LOWER GASTROINTESTINAL HAEMORRHAGE 404 0.0628
200 HYPOPHAGIA 1178 0.0627
201 HAEMOPTYSIS 1398 0.0626
202 BLOOD CREATININE INCREASED 3266 0.0626
203 RASH MACULO-PAPULAR 1024 0.0625
204 BASAL CELL CARCINOMA 741 0.0625
205 SPINAL COMPRESSION FRACTURE 446 0.0625
206 SINUS BRADYCARDIA 481 0.0625
207 ESCHERICHIA INFECTION 364 0.0623
208 ROTATOR CUFF SYNDROME 643 0.0623
209 APPENDICITIS 415 0.0622
210 MUSCULOSKELETAL CHEST PAIN 735 0.0620
211 FEELING OF BODY TEMPERATURE CHANGE 287 0.0620
212 JAUNDICE 1405 0.0619
213 TENDERNESS 513 0.0617
214 ACIDOSIS 375 0.0616
215 GLOMERULAR FILTRATION RATE DECREASED 481 0.0616
216 ARTERIOSCLEROSIS 475 0.0616
217 PLATELET COUNT INCREASED 600 0.0615
218 CONFUSIONAL STATE 7857 0.0614
219 PRODUCTIVE COUGH 2008 0.0614
220 FULL BLOOD COUNT ABNORMAL 319 0.0614
221 POST-TRAUMATIC STRESS DISORDER 299 0.0614
222 ERUCTATION 760 0.0614
223 SPINAL COLUMN STENOSIS 291 0.0614
224 HYPOTHYROIDISM 1391 0.0612
225 VENTRICULAR FIBRILLATION 548 0.0611
226 PANCYTOPENIA 2541 0.0611
227 MICTURITION URGENCY 527 0.0611
228 COORDINATION ABNORMAL 737 0.0609
229 RESTLESS LEGS SYNDROME 883 0.0609
230 HAEMORRHOIDS 939 0.0608
231 BLOOD POTASSIUM INCREASED 780 0.0608
232 PROTHROMBIN TIME PROLONGED 330 0.0608
233 PSEUDOMONAS INFECTION 364 0.0607
234 URINARY RETENTION 1548 0.0607
235 HEMIPARESIS 854 0.0605
236 GAMMA-GLUTAMYLTRANSFERASE INCREASED 1128 0.0605
237 ATRIAL FIBRILLATION 4547 0.0604
238 CARDIAC FAILURE ACUTE 287 0.0604
239 POSTOPERATIVE WOUND INFECTION 297 0.0604
240 DIVERTICULITIS 1262 0.0604
241 RESPIRATORY RATE INCREASED 410 0.0604
242 BODY HEIGHT DECREASED 572 0.0602
243 SKIN ULCER 1206 0.0602
244 ASCITES 1386 0.0602
245 RENAL PAIN 487 0.0601
246 CHROMATURIA 1090 0.0601
247 PNEUMONIA ASPIRATION 1127 0.0599
248 INTERSTITIAL LUNG DISEASE 2109 0.0598
249 PNEUMONIA BACTERIAL 349 0.0598
250 ABDOMINAL PAIN 10578 0.0597
251 VITAMIN D DECREASED 403 0.0596
252 ECCHYMOSIS 336 0.0594
253 ORAL PAIN 1050 0.0594
254 DELIRIUM 1504 0.0594
255 PERICARDITIS 567 0.0593
256 ANAEMIA 8888 0.0593
257 ACUTE MYOCARDIAL INFARCTION 1472 0.0593
258 SEPTIC SHOCK 1872 0.0592
259 PURPURA 424 0.0592
260 PULMONARY CONGESTION 597 0.0592
261 COVID-19 PNEUMONIA 422 0.0591
262 DERMATITIS BULLOUS 329 0.0591
263 PEMPHIGOID 294 0.0591
264 ELECTROCARDIOGRAM ABNORMAL 376 0.0590
265 URINARY INCONTINENCE 1373 0.0589
266 MOUTH HAEMORRHAGE 327 0.0589
267 RIB FRACTURE 932 0.0589
268 ABNORMAL FAECES 352 0.0589
269 HAEMOGLOBIN DECREASED 4770 0.0588
270 DRUG LEVEL INCREASED 749 0.0586
271 SWOLLEN TONGUE 1482 0.0586
272 SUBDURAL HAEMATOMA 697 0.0585
273 PULMONARY MASS 632 0.0585
274 LARGE INTESTINE POLYP 316 0.0585
275 DRUG ERUPTION 747 0.0585
276 LYMPHOEDEMA 294 0.0584
277 INTERVERTEBRAL DISC PROTRUSION 1035 0.0583
278 DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS 1028 0.0583
279 METABOLIC ACIDOSIS 1329 0.0581
280 SEDATION 1090 0.0580
281 EMPHYSEMA 481 0.0580
282 WHITE BLOOD CELL COUNT INCREASED 1792 0.0579
283 SYNOVITIS 699 0.0578
284 HEPATOMEGALY 476 0.0578
285 HYPERBILIRUBINAEMIA 445 0.0578
286 ANGINA PECTORIS 1400 0.0578
287 ALANINE AMINOTRANSFERASE INCREASED 2848 0.0578
288 INCONTINENCE 482 0.0577
289 OBESITY 659 0.0577
290 GENERALISED OEDEMA 528 0.0576
291 RENAL DISORDER 2071 0.0574
292 SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION 378 0.0574
293 TORSADE DE POINTES 360 0.0573
294 SEPSIS 4953 0.0573
295 DEHYDRATION 6039 0.0572
296 PNEUMONITIS 1069 0.0571
297 ARTHRITIS 3353 0.0571
298 GALLBLADDER DISORDER 848 0.0571
299 MUCOSAL INFLAMMATION 1125 0.0570
300 ANAL INCONTINENCE 315 0.0570
301 JOINT RANGE OF MOTION DECREASED 481 0.0569
302 PULMONARY HYPERTENSION 967 0.0569
303 URINARY TRACT INFECTION 7105 0.0569
304 UPPER-AIRWAY COUGH SYNDROME 324 0.0569
305 LUNG INFILTRATION 448 0.0568
306 BLOOD PRESSURE FLUCTUATION 1068 0.0566
307 FACIAL PARALYSIS 340 0.0565
308 ORAL DISORDER 323 0.0564
309 MULTIPLE ORGAN DYSFUNCTION SYNDROME 976 0.0563
310 BLOOD TEST ABNORMAL 548 0.0563
311 CORONARY ARTERY OCCLUSION 669 0.0563
312 ANGINA UNSTABLE 334 0.0563
313 SCIATICA 595 0.0562
314 HEPATITIS 1110 0.0562
315 GASTROINTESTINAL HAEMORRHAGE 4071 0.0561
316 BONE DISORDER 876 0.0560
317 ERYTHEMA MULTIFORME 414 0.0560
318 WOUND INFECTION 381 0.0559
319 INFLAMMATION 1939 0.0558
320 FOOT DEFORMITY 465 0.0556
321 FEBRILE NEUTROPENIA 2623 0.0556
322 PRESYNCOPE 1023 0.0556
323 CELLULITIS 2226 0.0556
324 FOOT FRACTURE 835 0.0555
325 MYOPATHY 375 0.0554
326 BALANCE DISORDER 3810 0.0554
327 COLITIS 1423 0.0553
328 LIPASE INCREASED 336 0.0553
329 IMMUNODEFICIENCY 503 0.0553
330 PETECHIAE 450 0.0553
331 COAGULOPATHY 747 0.0550
332 FLANK PAIN 399 0.0550
333 HYPOXIA 1439 0.0550
334 BODY TEMPERATURE DECREASED 441 0.0550
335 LEUKOCYTOSIS 764 0.0550
336 RESPIRATORY TRACT INFECTION 992 0.0550
337 MUSCLE STRAIN 368 0.0550
338 DRY MOUTH 3346 0.0549
339 OXYGEN SATURATION DECREASED 2116 0.0549
340 CARDIAC MURMUR 407 0.0548
341 CONSTIPATION 8495 0.0548
342 PLEURAL EFFUSION 2644 0.0548
343 PHARYNGITIS 539 0.0548
344 NECK PAIN 2332 0.0547
345 HYPOGLYCAEMIA 2138 0.0547
346 CHEST PAIN 8134 0.0547
347 CHOLECYSTECTOMY 472 0.0547
348 ABDOMINAL PAIN UPPER 8405 0.0545
349 FLATULENCE 2325 0.0545
350 LETHARGY 2505 0.0545
351 DYSPHAGIA 3866 0.0544
352 OEDEMA PERIPHERAL 5570 0.0543
353 CANDIDA INFECTION 625 0.0541
354 EATING DISORDER 903 0.0541
355 EOSINOPHIL COUNT INCREASED 329 0.0540
356 LIGAMENT SPRAIN 385 0.0539
357 GLOSSODYNIA 840 0.0539
358 SYNCOPE 4279 0.0539
359 BRADYCARDIA 2295 0.0539
360 HAEMORRHAGIC STROKE 348 0.0537
361 MYOCLONUS 510 0.0537
362 GINGIVAL PAIN 328 0.0537
363 BRONCHITIS 3173 0.0536
364 DIZZINESS POSTURAL 346 0.0536
365 HEPATIC CIRRHOSIS 727 0.0536
366 GROIN PAIN 376 0.0535
367 IMMUNOSUPPRESSION 302 0.0534
368 INCREASED TENDENCY TO BRUISE 397 0.0533
369 RED BLOOD CELL COUNT DECREASED 1146 0.0533
370 RIGHT VENTRICULAR FAILURE 320 0.0532
371 NERVE COMPRESSION 368 0.0532
372 HALLUCINATION, VISUAL 797 0.0532
373 MOTOR DYSFUNCTION 413 0.0531
374 LARGE INTESTINE PERFORATION 289 0.0531
375 ARTERIAL OCCLUSIVE DISEASE 348 0.0531
376 ASTHMA 3899 0.0528
377 SINUS CONGESTION 542 0.0527
378 PNEUMONIA 12574 0.0527
379 TRANSIENT ISCHAEMIC ATTACK 1468 0.0527
380 VENTRICULAR TACHYCARDIA 675 0.0527
381 LYMPHOCYTE COUNT DECREASED 709 0.0527
382 ASPARTATE AMINOTRANSFERASE INCREASED 2248 0.0526
383 ANURIA 380 0.0526
384 CORONARY ARTERY DISEASE 1444 0.0526
385 DRUG-INDUCED LIVER INJURY 965 0.0525
386 PALLOR 1032 0.0525
387 BLADDER DISORDER 417 0.0524
388 APHASIA 1266 0.0524
389 PSYCHOLOGICAL TRAUMA 436 0.0524
390 DEPRESSED LEVEL OF CONSCIOUSNESS 1611 0.0522
391 WOUND 966 0.0521
392 NEURALGIA 924 0.0521
393 GOUT 712 0.0521
394 BLOOD CHOLESTEROL INCREASED 1828 0.0521
395 HAEMATOMA 1122 0.0521
396 POLLAKIURIA 1672 0.0520
397 RESPIRATORY FAILURE 3002 0.0519
398 BRADYPHRENIA 286 0.0518
399 FEEDING DISORDER 638 0.0518
400 SEASONAL ALLERGY 463 0.0518
401 SINUS TACHYCARDIA 583 0.0518
402 SPINAL PAIN 444 0.0518
403 BACTERAEMIA 433 0.0517
404 LIP SWELLING 1326 0.0516
405 HICCUPS 316 0.0515
406 DYSARTHRIA 1546 0.0514
407 SQUAMOUS CELL CARCINOMA 377 0.0514
408 BLOOD CREATINE PHOSPHOKINASE INCREASED 1263 0.0513
409 HYPERGLYCAEMIA 1484 0.0513
410 PARKINSONISM 367 0.0513
411 ANKLE FRACTURE 620 0.0512
412 FALL 13076 0.0511
413 ATRIOVENTRICULAR BLOCK 309 0.0511
414 HYPOTENSION 7894 0.0511
415 CONTUSION 3717 0.0511
416 GINGIVAL BLEEDING 505 0.0510
417 ABDOMINAL DISTENSION 3963 0.0510
418 SINUSITIS 3885 0.0508
419 HAIR DISORDER 395 0.0507
420 DIARRHOEA 23785 0.0507
421 RASH PUSTULAR 322 0.0506
422 DIARRHOEA HAEMORRHAGIC 365 0.0506
423 CYST 478 0.0506
424 NODULE 489 0.0505
425 COGNITIVE DISORDER 1791 0.0505
426 VENTRICULAR EXTRASYSTOLES 429 0.0505
427 DECUBITUS ULCER 329 0.0504
428 MUSCULOSKELETAL DISCOMFORT 652 0.0503
429 UPPER RESPIRATORY TRACT INFECTION 1707 0.0503
430 WRIST FRACTURE 468 0.0503
431 BLOOD BILIRUBIN INCREASED 1109 0.0503
432 ECONOMIC PROBLEM 733 0.0503
433 MUSCULOSKELETAL PAIN 2351 0.0502
434 GASTROINTESTINAL INFLAMMATION 276 0.0501
435 IMPAIRED HEALING 1216 0.0501
436 ENCEPHALOPATHY 906 0.0501
437 LUNG DISORDER 1803 0.0501
438 SHOCK HAEMORRHAGIC 297 0.0500
439 HAND DEFORMITY 397 0.0500
440 COUGH 10028 0.0499
441 ARTHROPATHY 2099 0.0499
442 SPINAL DISORDER 368 0.0499
443 MASS 556 0.0499
444 JOINT DISLOCATION 392 0.0498
445 THROMBOCYTOPENIA 4161 0.0498
446 PULMONARY OEDEMA 1756 0.0498
447 DECREASED APPETITE 8373 0.0496
448 PERIPHERAL SWELLING 5378 0.0495
449 CONTRAINDICATED PRODUCT ADMINISTERED 1004 0.0495
450 PAROSMIA 285 0.0494
451 GASTROINTESTINAL PAIN 389 0.0494
452 PERICARDIAL EFFUSION 846 0.0493
453 OEDEMA 2012 0.0493
454 PELVIC FRACTURE 293 0.0493
455 NEUROPATHY PERIPHERAL 3303 0.0493
456 EXTRASYSTOLES 287 0.0492
457 PARAESTHESIA ORAL 525 0.0491
458 RESPIRATORY DISTRESS 1083 0.0491
459 NIGHT SWEATS 1144 0.0490
460 LIMB INJURY 946 0.0490
461 NAIL DISORDER 282 0.0489
462 HYPERTENSION 7847 0.0488
463 HERNIA 684 0.0488
464 CATARACT 2072 0.0488
465 SKIN LACERATION 334 0.0487
466 DISORIENTATION 1606 0.0487
467 ATAXIA 472 0.0486
468 SUBARACHNOID HAEMORRHAGE 383 0.0485
469 NEUTROPHIL COUNT DECREASED 1362 0.0485
470 CARDIOGENIC SHOCK 481 0.0485
471 DYSPHONIA 2120 0.0485
472 LUNG INFECTION 757 0.0484
473 MUSCULAR WEAKNESS 4249 0.0484
474 MOBILITY DECREASED 2557 0.0483
475 GASTRIC DISORDER 1571 0.0483
476 GASTROINTESTINAL INFECTION 312 0.0482
477 TYPE 2 DIABETES MELLITUS 1257 0.0482
478 VASCULITIS 408 0.0482
479 CARDIAC FAILURE 2970 0.0482
480 CYSTITIS 1233 0.0482
481 MULTI-ORGAN FAILURE 835 0.0481
482 DYSPNOEA 20898 0.0481
483 HEART RATE IRREGULAR 910 0.0481
484 SUDDEN DEATH 440 0.0480
485 MUSCLE RIGIDITY 443 0.0480
486 CYTOKINE RELEASE SYNDROME 303 0.0480
487 HEAD DISCOMFORT 605 0.0480
488 SKIN LESION 957 0.0480
489 VOMITING 17004 0.0480
490 TOOTH INFECTION 470 0.0480
491 SINUS DISORDER 710 0.0480
492 MUSCLE ATROPHY 429 0.0480
493 BLISTER 1970 0.0479
494 ILEUS 444 0.0479
495 DRY THROAT 371 0.0479
496 FACIAL PAIN 312 0.0478
497 JOINT INJURY 769 0.0477
498 APHONIA 474 0.0476
499 CHEST DISCOMFORT 3629 0.0476
500 HYPERTHERMIA 288 0.0475
501 SPINAL FRACTURE 696 0.0475
502 STAPHYLOCOCCAL INFECTION 1280 0.0474
503 SALIVARY HYPERSECRETION 359 0.0474
504 PULMONARY THROMBOSIS 383 0.0474
505 GASTROENTERITIS VIRAL 608 0.0473
506 HEPATIC FAILURE 1152 0.0473
507 OROPHARYNGEAL PAIN 3229 0.0473
508 JOINT SWELLING 4127 0.0472
509 STOMATITIS 2098 0.0472
510 ASTHENIA 13540 0.0472
511 INFUSION RELATED REACTION 2113 0.0472
512 ISCHAEMIC STROKE 678 0.0471
513 WEIGHT FLUCTUATION 333 0.0471
514 LIVER INJURY 654 0.0471
515 CROHN'S DISEASE 323 0.0471
516 BODY TEMPERATURE INCREASED 778 0.0470
517 EAR PAIN 692 0.0470
518 ALTERED STATE OF CONSCIOUSNESS 726 0.0470
519 BACK PAIN 8436 0.0469
520 HEPATIC FUNCTION ABNORMAL 1257 0.0469
521 INTESTINAL OBSTRUCTION 1259 0.0469
522 MENTAL STATUS CHANGES 1053 0.0468
523 THYROID DISORDER 540 0.0468
524 DIABETES MELLITUS INADEQUATE CONTROL 656 0.0468
525 PHOTOPHOBIA 636 0.0467
526 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 1345 0.0467
527 NERVE INJURY 416 0.0466
528 WEIGHT DECREASED 9894 0.0466
529 BLOOD TRIGLYCERIDES INCREASED 677 0.0466
530 HAIR COLOUR CHANGES 511 0.0465
531 BLOOD LACTATE DEHYDROGENASE INCREASED 620 0.0465
532 LACTIC ACIDOSIS 1033 0.0464
533 SKIN INFECTION 368 0.0464
534 PLATELET COUNT DECREASED 3711 0.0464
535 RASH PRURITIC 1824 0.0464
536 HALLUCINATION 2530 0.0463
537 PERIPHERAL COLDNESS 496 0.0462
538 PNEUMOTHORAX 546 0.0461
539 DISSEMINATED INTRAVASCULAR COAGULATION 537 0.0461
540 UNRESPONSIVE TO STIMULI 918 0.0459
541 PANCREATITIS 1925 0.0459
542 DEEP VEIN THROMBOSIS 2575 0.0459
543 DENTAL CARIES 409 0.0459
544 SWELLING FACE 2314 0.0458
545 BLOOD URINE PRESENT 699 0.0457
546 PYREXIA 12157 0.0457
547 HYPERAESTHESIA 314 0.0457
548 GENERAL PHYSICAL HEALTH DETERIORATION 3579 0.0455
549 ANGIOEDEMA 1530 0.0455
550 HEAD INJURY 1084 0.0453
551 LIVER DISORDER 1495 0.0453
552 EPISTAXIS 2664 0.0452
553 ARTHRALGIA 13365 0.0452
554 PULMONARY EMBOLISM 3585 0.0452
555 MUSCULOSKELETAL STIFFNESS 2973 0.0452
556 KNEE ARTHROPLASTY 609 0.0452
557 RETCHING 727 0.0452
558 TACHYCARDIA 3080 0.0451
559 BLOOD COUNT ABNORMAL 705 0.0451
560 TOOTH ABSCESS 377 0.0451
561 TENDON RUPTURE 459 0.0450
562 DIPLOPIA 881 0.0450
563 TOOTH DISORDER 810 0.0450
564 CHOKING 651 0.0449
565 OSTEOMYELITIS 671 0.0448
566 HAEMATOCHEZIA 1748 0.0448
567 BACTERIAL INFECTION 590 0.0447
568 THIRST 556 0.0447
569 MYALGIA 5895 0.0446
570 RASH ERYTHEMATOUS 1403 0.0446
571 EJECTION FRACTION DECREASED 530 0.0446
572 FACE OEDEMA 602 0.0445
573 HEART RATE DECREASED 1221 0.0445
574 ACUTE RESPIRATORY DISTRESS SYNDROME 610 0.0443
575 LOCALISED INFECTION 807 0.0443
576 GASTRIC HAEMORRHAGE 439 0.0442
577 POOR QUALITY SLEEP 687 0.0442
578 EYE INFECTION 341 0.0441
579 HYPOAESTHESIA ORAL 520 0.0441
580 LUPUS-LIKE SYNDROME 282 0.0440
581 VIRAL INFECTION 1032 0.0438
582 CEREBRAL INFARCTION 862 0.0438
583 PSORIATIC ARTHROPATHY 1044 0.0438
584 CARDIOMYOPATHY 522 0.0438
585 PAIN IN JAW 1009 0.0438
586 DIABETES MELLITUS 2715 0.0437
587 PARAESTHESIA 5341 0.0437
588 BACK DISORDER 549 0.0437
589 BACK INJURY 328 0.0436
590 PHOTOSENSITIVITY REACTION 559 0.0436
591 PALPITATIONS 3941 0.0436
592 THROAT IRRITATION 1424 0.0435
593 HUNGER 348 0.0435
594 PAIN IN EXTREMITY 10157 0.0435
595 HYPERHIDROSIS 4415 0.0435
596 EAR INFECTION 784 0.0434
597 PHARYNGEAL OEDEMA 656 0.0434
598 INTESTINAL PERFORATION 374 0.0434
599 COLD SWEAT 607 0.0434
600 TOOTH FRACTURE 380 0.0434
601 MUSCLE SPASMS 6193 0.0433
602 BLOOD PRESSURE DECREASED 2218 0.0432
603 LARYNGITIS 337 0.0431
604 AFFECT LABILITY 353 0.0431
605 TASTE DISORDER 406 0.0431
606 ANAPHYLACTIC REACTION 1662 0.0431
607 TINNITUS 1527 0.0430
608 ABDOMINAL DISCOMFORT 5295 0.0430
609 LOWER LIMB FRACTURE 572 0.0430
610 TRANSFUSION 355 0.0429
611 LEUKOPENIA 1623 0.0428
612 RHINORRHOEA 1964 0.0427
613 RESPIRATORY TRACT CONGESTION 494 0.0427
614 HIP ARTHROPLASTY 431 0.0426
615 MUSCLE DISORDER 288 0.0426
616 SLEEP DISORDER 2098 0.0426
617 ANOREXIA 547 0.0424
618 SWELLING 2937 0.0424
619 LYMPHOPENIA 433 0.0424
620 DERMATITIS ALLERGIC 367 0.0424
621 ORAL DISCOMFORT 464 0.0424
622 BLOOD PRESSURE INCREASED 4976 0.0423
623 VERTIGO 2047 0.0423
624 DEPRESSION 7970 0.0423
625 GASTROINTESTINAL DISORDER 2369 0.0423
626 HYPOTHERMIA 333 0.0423
627 CYANOSIS 534 0.0422
628 INFLUENZA 3161 0.0422
629 BURNING SENSATION 2335 0.0421
630 NAUSEA 25251 0.0421
631 HAIR TEXTURE ABNORMAL 505 0.0421
632 CEREBRAL HAEMORRHAGE 1202 0.0420
633 MALAISE 14651 0.0419
634 RHEUMATOID ARTHRITIS 3448 0.0419
635 BONE PAIN 1919 0.0419
636 RESPIRATORY DISORDER 961 0.0418
637 TREMOR 5571 0.0418
638 DEVICE RELATED INFECTION 534 0.0418
639 DIZZINESS 15951 0.0416
640 NEUTROPENIA 3948 0.0416
641 CONDITION AGGRAVATED 8383 0.0415
642 PEMPHIGUS 292 0.0415
643 SPINAL OPERATION 281 0.0413
644 HEART RATE INCREASED 3126 0.0413
645 MUSCLE TWITCHING 755 0.0413
646 EAR DISCOMFORT 310 0.0413
647 DRY EYE 1191 0.0413
648 ARRHYTHMIA 1587 0.0413
649 BLOOD PRESSURE ABNORMAL 569 0.0413
650 TEMPERATURE INTOLERANCE 304 0.0412
651 HYPERTHYROIDISM 435 0.0412
652 STEVENS-JOHNSON SYNDROME 757 0.0412
653 LOCAL SWELLING 719 0.0412
654 TOOTHACHE 573 0.0412
655 CONJUNCTIVITIS 495 0.0412
656 FULL BLOOD COUNT DECREASED 577 0.0411
657 ECZEMA 862 0.0411
658 HYPERTENSIVE CRISIS 366 0.0410
659 CARDIO-RESPIRATORY ARREST 1436 0.0410
660 TACHYPNOEA 406 0.0410
661 LYMPHADENOPATHY 1103 0.0409
662 UPPER LIMB FRACTURE 671 0.0408
663 EYE HAEMORRHAGE 439 0.0408
664 PRURITUS GENERALISED 884 0.0408
665 NASAL CONGESTION 1660 0.0407
666 CHILLS 3672 0.0407
667 RASH MACULAR 1024 0.0407
668 GLAUCOMA 610 0.0406
669 POST PROCEDURAL COMPLICATION 625 0.0406
670 ANHEDONIA 962 0.0406
671 FEELING COLD 880 0.0405
672 THROAT TIGHTNESS 848 0.0403
673 FLUID OVERLOAD 590 0.0403
674 GAIT INABILITY 776 0.0402
675 SOMNOLENCE 6263 0.0401
676 NIGHTMARE 1127 0.0401
677 BRONCHOSPASM 462 0.0401
678 CARDIAC FAILURE CONGESTIVE 2912 0.0400
679 HYPERSOMNIA 869 0.0400
680 WHITE BLOOD CELL COUNT DECREASED 3243 0.0399
681 FEELING HOT 1847 0.0399
682 SECRETION DISCHARGE 326 0.0398
683 DEPRESSED MOOD 1566 0.0398
684 SKIN HAEMORRHAGE 343 0.0397
685 LOSS OF CONSCIOUSNESS 4039 0.0397
686 FLUID RETENTION 1593 0.0397
687 FATIGUE 22795 0.0397
688 TRANSAMINASES INCREASED 698 0.0396
689 INFECTION 4074 0.0396
690 DYSSTASIA 913 0.0395
691 LIVER FUNCTION TEST INCREASED 536 0.0395
692 HYPOAESTHESIA 4594 0.0393
693 FREQUENT BOWEL MOVEMENTS 680 0.0393
694 PARANOIA 553 0.0393
695 SCHIZOPHRENIA 341 0.0392
696 AGEUSIA 760 0.0392
697 JOINT STIFFNESS 775 0.0391
698 GAIT DISTURBANCE 5854 0.0389
699 DYSKINESIA 1245 0.0388
700 HEPATIC ENZYME INCREASED 1890 0.0388
701 DELUSION 450 0.0387
702 INSOMNIA 8189 0.0387
703 VISION BLURRED 3971 0.0386
704 DYSGEUSIA 2303 0.0385
705 LIMB DISCOMFORT 895 0.0385
706 HYPOKINESIA 447 0.0383
707 AMNESIA 2042 0.0383
708 SYSTEMIC LUPUS ERYTHEMATOSUS 852 0.0383
709 HIP FRACTURE 931 0.0383
710 AGITATION 2329 0.0382
711 SPEECH DISORDER 1593 0.0382
712 ANXIETY 8699 0.0381
713 STRESS 1995 0.0381
714 FEMUR FRACTURE 993 0.0380
715 SNEEZING 600 0.0380
716 LACERATION 358 0.0380
717 SKIN DISCOLOURATION 1351 0.0378
718 EYE PAIN 1439 0.0378
719 HEADACHE 18186 0.0376
720 FUNGAL INFECTION 942 0.0376
721 SENSORY DISTURBANCE 510 0.0376
722 ACUTE HEPATIC FAILURE 371 0.0375
723 RASH GENERALISED 973 0.0374
724 HERPES ZOSTER 1648 0.0374
725 MULTIPLE FRACTURES 521 0.0374
726 DERMATITIS 530 0.0373
727 DISCOMFORT 1501 0.0372
728 MIDDLE INSOMNIA 509 0.0371
729 ABSCESS 440 0.0371
730 PRURITUS 9348 0.0370
731 ORAL HERPES 499 0.0370
732 METASTASES TO LIVER 479 0.0370
733 INTERNAL HAEMORRHAGE 336 0.0369
734 NASOPHARYNGITIS 4789 0.0368
735 PRESCRIBED OVERDOSE 539 0.0368
736 PAIN 17574 0.0367
737 MUSCLE SPASTICITY 382 0.0366
738 GENERALISED TONIC-CLONIC SEIZURE 417 0.0366
739 HAEMORRHAGE INTRACRANIAL 470 0.0366
740 HALLUCINATION, AUDITORY 444 0.0366
741 DECREASED ACTIVITY 275 0.0364
742 IMPAIRED QUALITY OF LIFE 306 0.0364
743 BIPOLAR DISORDER 333 0.0364
744 BREAST PAIN 322 0.0363
745 INCORRECT DRUG ADMINISTRATION DURATION 1021 0.0363
746 MIGRAINE 2465 0.0362
747 FISTULA 290 0.0361
748 PLASMA CELL MYELOMA 1028 0.0360
749 CARDIAC ARREST 2400 0.0360
750 THROMBOSIS 2296 0.0359
751 METASTASES TO BONE 402 0.0359
752 HEPATOTOXICITY 574 0.0357
753 NEUROLEPTIC MALIGNANT SYNDROME 338 0.0357
754 ILL-DEFINED DISORDER 1130 0.0357
755 IMMUNE SYSTEM DISORDER 346 0.0357
756 THINKING ABNORMAL 560 0.0355
757 DISTURBANCE IN ATTENTION 1533 0.0354
758 SCAR 485 0.0354
759 DEMENTIA 689 0.0354
760 BEDRIDDEN 363 0.0353
761 BRAIN OEDEMA 348 0.0353
762 MADAROSIS 376 0.0352
763 WEIGHT INCREASED 5933 0.0352
764 MEMORY IMPAIRMENT 3727 0.0351
765 RESTLESSNESS 1016 0.0350
766 FLUSHING 2980 0.0349
767 POLYNEUROPATHY 292 0.0349
768 NERVOUSNESS 1557 0.0349
769 MACULAR DEGENERATION 310 0.0348
770 MOVEMENT DISORDER 880 0.0347
771 ABASIA 856 0.0346
772 METASTASES TO LUNG 287 0.0345
773 MANIA 457 0.0345
774 SHOCK 585 0.0343
775 MUSCULOSKELETAL DISORDER 529 0.0343
776 BONE MARROW FAILURE 630 0.0343
777 PANIC ATTACK 985 0.0343
778 ACTIVITIES OF DAILY LIVING IMPAIRED 679 0.0342
779 ABDOMINAL PAIN LOWER 689 0.0342
780 HOT FLUSH 1808 0.0342
781 MUSCLE TIGHTNESS 442 0.0341
782 SEIZURE 2683 0.0341
783 RASH 10653 0.0339
784 INTENTIONAL PRODUCT USE ISSUE 1917 0.0339
785 FEELING JITTERY 537 0.0339
786 DRUG INTOLERANCE 2310 0.0338
787 TOOTH EXTRACTION 334 0.0337
788 SKIN DISORDER 785 0.0336
789 POST PROCEDURAL HAEMORRHAGE 321 0.0336
790 ROAD TRAFFIC ACCIDENT 1081 0.0335
791 URTICARIA 4089 0.0334
792 OSTEONECROSIS OF JAW 714 0.0333
793 SKIN FISSURES 344 0.0331
794 ILLNESS 1139 0.0330
795 PRESCRIBED UNDERDOSE 464 0.0330
796 DEAFNESS 645 0.0330
797 PULMONARY ARTERIAL HYPERTENSION 394 0.0328
798 LACRIMATION INCREASED 671 0.0328
799 MALIGNANT MELANOMA 343 0.0327
800 SOPOR 374 0.0327
801 METASTASES TO CENTRAL NERVOUS SYSTEM 288 0.0326
802 DISEASE RECURRENCE 868 0.0326
803 OVARIAN CYST 275 0.0325
804 GRAND MAL CONVULSION 300 0.0325
805 STATUS EPILEPTICUS 283 0.0324
806 ACUTE MYELOID LEUKAEMIA 378 0.0324
807 EPILEPSY 711 0.0323
808 EYELID OEDEMA 332 0.0323
809 ERYTHEMA 5078 0.0321
810 MYELODYSPLASTIC SYNDROME 369 0.0320
811 INCREASED APPETITE 405 0.0319
812 RASH PAPULAR 580 0.0319
813 PARALYSIS 363 0.0319
814 MENTAL IMPAIRMENT 609 0.0318
815 PERITONITIS 538 0.0317
816 THERAPY NON-RESPONDER 839 0.0317
817 THERAPEUTIC PRODUCT EFFECT DECREASED 823 0.0316
818 COMA 1189 0.0316
819 DIABETIC KETOACIDOSIS 591 0.0313
820 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 295 0.0313
821 ERECTILE DYSFUNCTION 609 0.0313
822 ALOPECIA 4860 0.0313
823 DISEASE PROGRESSION 2538 0.0312
824 PROSTATIC SPECIFIC ANTIGEN INCREASED 330 0.0310
825 FEELING ABNORMAL 6067 0.0310
826 PRODUCT SUBSTITUTION ISSUE 1425 0.0310
827 PSYCHOTIC DISORDER 722 0.0308
828 BLINDNESS UNILATERAL 334 0.0308
829 ABNORMAL DREAMS 734 0.0308
830 HYPERSENSITIVITY 4369 0.0308
831 INFLUENZA LIKE ILLNESS 2084 0.0307
832 CARDIAC DISORDER 2302 0.0306
833 COLON CANCER 357 0.0305
834 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 1234 0.0304
835 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 538 0.0304
836 APATHY 340 0.0303
837 CYTOMEGALOVIRUS INFECTION 378 0.0303
838 ANAPHYLACTIC SHOCK 559 0.0303
839 VISUAL IMPAIRMENT 2669 0.0302
840 SUICIDAL IDEATION 2198 0.0302
841 THERAPY INTERRUPTED 686 0.0301
842 TREATMENT NONCOMPLIANCE 1122 0.0301
843 MEDICATION ERROR 1302 0.0298
844 HAEMORRHAGE 2337 0.0298
845 FRACTURE 448 0.0298
846 QUALITY OF LIFE DECREASED 305 0.0294
847 TOXICITY TO VARIOUS AGENTS 3557 0.0293
848 CEREBROVASCULAR ACCIDENT 4110 0.0292
849 COLITIS ULCERATIVE 776 0.0292
850 INJURY 1757 0.0292
851 SURGERY 1113 0.0292
852 FEAR 691 0.0291
853 TUBERCULOSIS 282 0.0290
854 SKIN CANCER 463 0.0287
855 DRUG TOXICITY 391 0.0287
856 THERAPEUTIC RESPONSE UNEXPECTED 1033 0.0284
857 EYE DISORDER 693 0.0283
858 LABORATORY TEST ABNORMAL 629 0.0283
859 EYE SWELLING 788 0.0281
860 MENTAL DISORDER 948 0.0281
861 LYMPHOMA 340 0.0280
862 OFF LABEL USE 14328 0.0279
863 PRODUCT PRESCRIBING ERROR 381 0.0278
864 CONVULSION 1594 0.0278
865 MALIGNANT NEOPLASM PROGRESSION 1987 0.0278
866 WITHDRAWAL SYNDROME 856 0.0278
867 PSYCHOMOTOR HYPERACTIVITY 389 0.0277
868 MOOD ALTERED 581 0.0274
869 COVID-19 2353 0.0274
870 SKIN EXFOLIATION 1609 0.0273
871 PROCEDURAL PAIN 543 0.0272
872 PRODUCT ADMINISTRATION ERROR 309 0.0271
873 INTENTIONAL SELF-INJURY 429 0.0271
874 IMPAIRED WORK ABILITY 480 0.0271
875 MYOCARDIAL INFARCTION 4171 0.0269
876 INTENTIONAL PRODUCT MISUSE 1762 0.0269
877 MOOD SWINGS 718 0.0269
878 ABNORMAL BEHAVIOUR 928 0.0268
879 HEPATITIS C 295 0.0268
880 VISUAL ACUITY REDUCED 808 0.0267
881 BLINDNESS 802 0.0266
882 EMOTIONAL DISORDER 673 0.0266
883 GLYCOSYLATED HAEMOGLOBIN INCREASED 488 0.0265
884 HYPOACUSIS 786 0.0263
885 THERAPY CESSATION 952 0.0263
886 NO THERAPEUTIC RESPONSE 319 0.0261
887 NEUROTOXICITY 309 0.0260
888 DRUG PRESCRIBING ERROR 501 0.0260
889 BONE DENSITY DECREASED 711 0.0260
890 PSORIASIS 2485 0.0260
891 DRUG HYPERSENSITIVITY 4016 0.0259
892 AGGRESSION 1079 0.0259
893 PRODUCT USE ISSUE 3434 0.0256
894 IRRITABILITY 1255 0.0252
895 PELVIC PAIN 364 0.0252
896 INTENTIONAL DRUG MISUSE 526 0.0251
897 PRODUCT USE IN UNAPPROVED INDICATION 3661 0.0251
898 PRODUCT DOSE OMISSION 1668 0.0250
899 UNEVALUABLE EVENT 1534 0.0249
900 BLOOD GLUCOSE DECREASED 987 0.0248
901 RESPIRATORY ARREST 598 0.0246
902 BLOOD GLUCOSE ABNORMAL 352 0.0246
903 INJECTION SITE EXTRAVASATION 287 0.0246
904 NEOPLASM PROGRESSION 636 0.0245
905 THERAPEUTIC RESPONSE SHORTENED 288 0.0245
906 WRONG TECHNIQUE IN DRUG USAGE PROCESS 887 0.0244
907 TOOTH LOSS 417 0.0243
908 CRYING 746 0.0242
909 ANGER 672 0.0237
910 DYSTONIA 391 0.0235
911 PRODUCT DOSE OMISSION ISSUE 2575 0.0235
912 EYE PRURITUS 478 0.0234
913 OCULAR HYPERAEMIA 746 0.0234
914 GASTRIC CANCER 512 0.0232
915 BLOOD GLUCOSE INCREASED 3537 0.0229
916 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 1632 0.0229
917 DRUG DOSE OMISSION 3756 0.0227
918 ACCIDENTAL OVERDOSE 596 0.0226
919 CARDIOVASCULAR DISORDER 511 0.0225
920 ADVERSE DRUG REACTION 1329 0.0222
921 THERAPEUTIC RESPONSE DECREASED 971 0.0220
922 INCORRECT DOSE ADMINISTERED 3007 0.0220
923 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 783 0.0219
924 NERVOUS SYSTEM DISORDER 581 0.0219
925 OSTEONECROSIS 631 0.0218
926 DRUG EFFECT DECREASED 1166 0.0216
927 HOSPITALISATION 2157 0.0215
928 EYE IRRITATION 783 0.0215
929 PHARMACEUTICAL PRODUCT COMPLAINT 556 0.0214
930 EXTRA DOSE ADMINISTERED 445 0.0213
931 INJECTION SITE HAEMATOMA 290 0.0213
932 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 1811 0.0209
933 LUNG NEOPLASM MALIGNANT 723 0.0208
934 INJECTION SITE MASS 548 0.0207
935 PRODUCT PHYSICAL ISSUE 286 0.0206
936 DRUG INEFFECTIVE 20181 0.0205
937 DISABILITY 311 0.0203
938 INJECTION SITE RASH 423 0.0203
939 DRY SKIN 1849 0.0203
940 INTENTIONAL OVERDOSE 922 0.0202
941 INJECTION SITE PRURITUS 1003 0.0201
942 EXTRAPYRAMIDAL DISORDER 446 0.0197
943 SUICIDE ATTEMPT 934 0.0197
944 TREATMENT FAILURE 1091 0.0195
945 EMOTIONAL DISTRESS 2084 0.0195
946 DRUG EFFECT INCOMPLETE 709 0.0195
947 INJECTION SITE HAEMORRHAGE 1099 0.0194
948 MULTIPLE SCLEROSIS 736 0.0194
949 INJECTION SITE BRUISING 1099 0.0193
950 INJECTION SITE URTICARIA 318 0.0192
951 INJECTION SITE PAIN 3964 0.0190
952 DRUG DISPENSING ERROR 291 0.0190
953 DRUG ADMINISTRATION ERROR 581 0.0189
954 ADVERSE EVENT 1333 0.0186
955 INJECTION SITE ERYTHEMA 1740 0.0184
956 MULTIPLE SCLEROSIS RELAPSE 1078 0.0183
957 NEOPLASM MALIGNANT 894 0.0182
958 NEEDLE ISSUE 293 0.0181
959 COMPLETED SUICIDE 1259 0.0180
960 TARDIVE DYSKINESIA 464 0.0180
961 DEVICE MALFUNCTION 786 0.0180
962 DEATH 11359 0.0177
963 EXPIRED PRODUCT ADMINISTERED 442 0.0176
964 PRODUCT QUALITY ISSUE 2071 0.0175
965 OVERDOSE 2922 0.0174
966 INJECTION SITE REACTION 926 0.0174
967 PREMATURE BABY 419 0.0174
968 EXPOSURE DURING PREGNANCY 768 0.0171
969 PAIN OF SKIN 362 0.0170
970 INJECTION SITE SWELLING 878 0.0163
971 VAGINAL HAEMORRHAGE 590 0.0161
972 INJECTION SITE WARMTH 276 0.0160
973 MATERNAL EXPOSURE DURING PREGNANCY 907 0.0160
974 UNDERDOSE 880 0.0157
975 DEVICE ISSUE 853 0.0153
976 PANCREATIC CARCINOMA 352 0.0144
977 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 1861 0.0138
978 APPLICATION SITE ERYTHEMA 305 0.0132
979 NO ADVERSE EVENT 1395 0.0128
980 FOETAL EXPOSURE DURING PREGNANCY 760 0.0126
981 DRUG WITHDRAWAL SYNDROME 1017 0.0125
982 PRODUCT ADHESION ISSUE 292 0.0116
983 DRUG ABUSE 716 0.0113
984 SKIN BURNING SENSATION 626 0.0109
985 DEVICE DISLOCATION 362 0.0108
986 ACNE 659 0.0105
987 SKIN IRRITATION 389 0.0104
988 PRODUCT STORAGE ERROR 371 0.0101
989 INCORRECT ROUTE OF DRUG ADMINISTRATION 355 0.0099
990 DRUG DEPENDENCE 1385 0.0096
991 BREAST CANCER 798 0.0093
992 DRUG EXPOSURE DURING PREGNANCY 286 0.0084
993 RENAL CANCER 327 0.0072
994 PROSTATE CANCER 510 0.0069
995 ACCIDENTAL EXPOSURE TO PRODUCT 311 0.0061
996 BLADDER CANCER 281 0.0054