ACQUIRED GENE MUTATION

ACQUIRED GENE MUTATION was reported 812 times

ACQUIRED GENE MUTATION is most prevalent among patients taking these drug classes:

# Drug class Count Frequency
0 Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 144 0.0034
1 Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 69 0.0016
2 Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 159 0.0016
3 Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 21 0.0011
4 CCR5 Co-receptor Antagonist [EPC] 2 0.0011
5 Hedgehog Pathway Inhibitor [EPC] 7 0.0011
6 Kinase Inhibitor [EPC] 350 0.0010
7 Topoisomerase Inhibitor [EPC] 34 0.0008
8 Alkylating Drug [EPC] 110 0.0007
9 CD20-directed Cytolytic Antibody [EPC] 100 0.0007
10 Platinum-based Drug [EPC] 87 0.0006
11 Estrogen Receptor Antagonist [EPC] 9 0.0005
12 Echinocandin Antifungal [EPC] 2 0.0005
13 Protease Inhibitor [EPC] 17 0.0005
14 Purine Antimetabolite [EPC] 26 0.0004
15 Cytochrome P450 3A Inhibitor [EPC] 19 0.0004
16 Microtubule Inhibitor [EPC] 36 0.0004
17 Aromatase Inhibitor [EPC] 22 0.0003
18 Somatostatin Analog [EPC] 1 0.0003
19 Nucleoside Metabolic Inhibitor [EPC] 40 0.0002
20 Vascular Endothelial Growth Factor Inhibitor [EPC] 24 0.0002
21 Programmed Death Receptor-1 Blocking Antibody [EPC] 18 0.0002
22 HER2/neu Receptor Antagonist [EPC] 8 0.0002
23 Epidermal Growth Factor Receptor Antagonist [EPC] 6 0.0002
24 Corticosteroid [EPC] 140 0.0002
25 CD52-directed Cytolytic Antibody [EPC] 2 0.0002
26 Azole Antifungal [EPC] 16 0.0002
27 Programmed Death Ligand-1 Blocker [EPC] 1 0.0001
28 Androgen Receptor Inhibitor [EPC] 8 0.0001
29 BCL-2 Inhibitor [EPC] 2 0.0001
30 Recombinant Human Growth Hormone [EPC] 1 0.0001
31 Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 1 0.0001
32 Antimycobacterial [EPC] 1 0.0001
33 Folate Analog Metabolic Inhibitor [EPC] 18 0.0001
34 Rifamycin Antibacterial [EPC] 1 0.0001
35 Oxazolidinone Antibacterial [EPC] 1 0.0001
36 Lincosamide Antibacterial [EPC] 1 0.0000
37 Complement Inhibitor [EPC] 2 0.0000
38 Phenothiazine [EPC] 1 0.0000
39 Macrolide Antimicrobial [EPC] 2 0.0000
40 Opioid Agonist [EPC] 9 0.0000
41 Iron Chelator [EPC] 1 0.0000
42 Nucleoside Analog Antiviral [EPC] 3 0.0000
43 Quinolone Antimicrobial [EPC] 3 0.0000
44 RANK Ligand Inhibitor [EPC] 5 0.0000
45 Tetracycline-class Drug [EPC] 1 0.0000
46 Thalidomide Analog [EPC] 8 0.0000
47 Leukocyte Growth Factor [EPC] 2 0.0000
48 Methylxanthine [EPC] 3 0.0000
49 Benzodiazepine [EPC] 10 0.0000
50 Calcium [EPC] 2 0.0000
51 Angiotensin Converting Enzyme Inhibitor [EPC] 2 0.0000
52 Mood Stabilizer [EPC] 3 0.0000
53 Phosphate Binder [EPC] 2 0.0000
54 Central Nervous System Stimulant [EPC] 3 0.0000
55 Vitamin D [EPC] 3 0.0000
56 Interleukin-12 Antagonist [EPC] 1 0.0000
57 Potassium Channel Blocker [EPC] 1 0.0000
58 Vitamin B12 [EPC] 3 0.0000
59 Vitamin C [EPC] 3 0.0000
60 Dihydrofolate Reductase Inhibitor Antibacterial [EPC] 1 0.0000
61 Atypical Antipsychotic [EPC] 5 0.0000
62 Interleukin-23 Antagonist [EPC] 1 0.0000
63 Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 1 0.0000
64 Erythropoiesis-stimulating Agent [EPC] 1 0.0000
65 Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 1 0.0000
66 Interleukin-6 Receptor Antagonist [EPC] 1 0.0000
67 Serotonin-3 Receptor Antagonist [EPC] 1 0.0000
68 HMG-CoA Reductase Inhibitor [EPC] 4 0.0000
69 Nonsteroidal Anti-inflammatory Drug [EPC] 12 0.0000
70 Provitamin D2 Compound [EPC] 3 0.0000
71 Thiazide Diuretic [EPC] 2 0.0000
72 Selective T Cell Costimulation Modulator [EPC] 1 0.0000
73 Aldosterone Antagonist [EPC] 1 0.0000
74 alpha-Adrenergic Blocker [EPC] 1 0.0000
75 Anti-epileptic Agent [EPC] 4 0.0000
76 l-Thyroxine [EPC] 1 0.0000
77 Xanthine Oxidase Inhibitor [EPC] 1 0.0000
78 Platelet Aggregation Inhibitor [EPC] 4 0.0000
79 Proton Pump Inhibitor [EPC] 3 0.0000
80 Estrogen [EPC] 1 0.0000
81 Loop Diuretic [EPC] 2 0.0000
82 Integrin Receptor Antagonist [EPC] 1 0.0000
83 Retinoid [EPC] 1 0.0000
84 Progestin [EPC] 1 0.0000
85 beta-Adrenergic Blocker [EPC] 1 0.0000
86 Angiotensin 2 Receptor Blocker [EPC] 1 0.0000
87 Factor Xa Inhibitor [EPC] 1 0.0000
88 Tumor Necrosis Factor Blocker [EPC] 2 0.0000