AGGRESSION

AGGRESSION was reported 42645 times

AGGRESSION is most prevalent among patients taking these drug classes:

# Drug class Count Frequency
0 Noncompetitive AMPA Glutamate Receptor Antagonist [EPC] 404 0.0842
1 Cholinesterase Inhibitor [EPC] 428 0.0288
2 Typical Antipsychotic [EPC] 484 0.0245
3 Dopamine-2 Receptor Antagonist [EPC] 131 0.0241
4 Melanocortin 4 Receptor Agonist [EPC] 1 0.0233
5 Neuraminidase Inhibitor [EPC] 58 0.0224
6 Partial Opioid Agonist/Antagonist [EPC] 1 0.0208
7 Catechol-O-Methyltransferase Inhibitor [EPC] 233 0.0204
8 Atypical Antipsychotic [EPC] 6084 0.0144
9 Anti-epileptic Agent [EPC] 2621 0.0137
10 Mood Stabilizer [EPC] 2439 0.0137
11 Vesicular Monoamine Transporter 2 Inhibitor [EPC] 94 0.0135
12 Monobactam Antibacterial [EPC] 28 0.0133
13 Central alpha-2 Adrenergic Agonist [EPC] 617 0.0132
14 Leukotriene Receptor Antagonist [EPC] 224 0.0126
15 Aromatic Amino Acid Decarboxylation Inhibitor [EPC] 538 0.0120
16 Central Nervous System Stimulant [EPC] 742 0.0114
17 Aromatic Amino Acid [EPC] 575 0.0113
18 Influenza A M2 Protein Inhibitor [EPC] 124 0.0100
19 Tricyclic Antidepressant [EPC] 4 0.0098
20 Benzodiazepine [EPC] 5367 0.0091
21 Monoamine Oxidase Inhibitor [EPC] 23 0.0088
22 Aldehyde Dehydrogenase Inhibitor [EPC] 7 0.0085
23 Tubulin Inhibiting Agent [EPC] 2 0.0083
24 Benzodiazepine Antagonist [EPC] 5 0.0079
25 Nonergot Dopamine Agonist [EPC] 172 0.0077
26 Sigma-1 Agonist [EPC] 48 0.0074
27 Carnitine Analog [EPC] 17 0.0073
28 Ergot Derivative [EPC] 27 0.0071
29 Serotonin Reuptake Inhibitor [EPC] 494 0.0071
30 gamma-Aminobutyric Acid A Receptor Agonist [EPC] 9 0.0070
31 Serotonin and Norepinephrine Reuptake Inhibitor [EPC] 295 0.0067
32 Cannabinoid [EPC] 50 0.0064
33 Histamine-1 Receptor Antagonist [EPC] 218 0.0060
34 Amyloid Beta-directed Antibody [EPC] 2 0.0054
35 Glucosylceramide Synthase Inhibitor [EPC] 10 0.0053
36 Androgen [EPC] 207 0.0051
37 Methylating Agent [EPC] 4 0.0049
38 Muscle Relaxant [EPC] 178 0.0047
39 Recombinant Human Growth Hormone [EPC] 60 0.0046
40 Sympathomimetic-like Agent [EPC] 128 0.0045
41 Glycolipid Disialoganglioside-directed Antibody [EPC] 3 0.0044
42 Benzothiazole [EPC] 7 0.0043
43 Antidote [EPC] 40 0.0043
44 Non-Standardized Plant Allergenic Extract [EPC] 39 0.0040
45 Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] 1 0.0040
46 Vitamin B6 Analog [EPC] 1 0.0039
47 General Anesthetic [EPC] 127 0.0039
48 Standardized Chemical Allergen [EPC] 49 0.0038
49 5-alpha Reductase Inhibitor [EPC] 220 0.0037
50 Osmotic Laxative [EPC] 647 0.0037
51 Antimalarial [EPC] 25 0.0036
52 5-Lipoxygenase Inhibitor [EPC] 2 0.0036
53 Penem Antibacterial [EPC] 5 0.0036
54 Opioid Agonist [EPC] 833 0.0035
55 Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] 47 0.0035
56 Melatonin Receptor Agonist [EPC] 38 0.0034
57 Interferon alpha [EPC] 191 0.0034
58 Leptin Analog [EPC] 3 0.0033
59 Non-Standardized Insect Allergenic Extract [EPC] 13 0.0033
60 Macrolide Antimicrobial [EPC] 135 0.0033
61 Stimulant Laxative [EPC] 35 0.0032
62 Recombinant Human Deoxyribonuclease 1 [EPC] 54 0.0032
63 Cephalosporin Antibacterial [EPC] 21 0.0031
64 Antihypoglycemic Agent [EPC] 9 0.0031
65 Anthelmintic [EPC] 7 0.0031
66 Osmotic Diuretic [EPC] 12 0.0030
67 Angiotensin Converting Enzyme Inhibitor [EPC] 360 0.0030
68 Orexin Receptor Antagonist [EPC] 39 0.0030
69 Antiprotozoal [EPC] 26 0.0029
70 gamma-Aminobutyric Acid-ergic Agonist [EPC] 208 0.0029
71 Anticholinergic [EPC] 35 0.0028
72 Vitamin A [EPC] 141 0.0028
73 Nucleoside Analog Antiviral [EPC] 220 0.0028
74 Cystic Fibrosis Transmembrane Conductance Regulator Potentiator [EPC] 39 0.0028
75 HMG-CoA Reductase Inhibitor [EPC] 957 0.0027
76 Standardized Insect Venom Allergenic Extract [EPC] 14 0.0027
77 Barbiturate [EPC] 27 0.0026
78 Cholinergic Nicotinic Agonist [EPC] 143 0.0026
79 Carbonic Anhydrase Inhibitor [EPC] 42 0.0026
80 Nicotinic Acid [EPC] 158 0.0026
81 l-Thyroxine [EPC] 369 0.0026
82 Serotonin-1b and Serotonin-1d Receptor Agonist [EPC] 94 0.0025
83 Non-Standardized Fungal Allergenic Extract [EPC] 8 0.0025
84 Non-Standardized Chemical Allergen [EPC] 22 0.0025
85 4-Hydroxyphenyl-Pyruvate Dioxygenase Inhibitor [EPC] 2 0.0024
86 Methylxanthine [EPC] 100 0.0024
87 Nitrate Vasodilator [EPC] 185 0.0024
88 Proton Pump Inhibitor [EPC] 1087 0.0023
89 Adrenocorticotropic Hormone [EPC] 2 0.0023
90 Peroxisome Proliferator Receptor alpha Agonist [EPC] 152 0.0023
91 Antifibrinolytic Agent [EPC] 16 0.0022
92 Partial Opioid Agonist [EPC] 175 0.0022
93 Plasma Volume Expander [EPC] 5 0.0022
94 Pyrethroid [EPC] 3 0.0022
95 Nonsteroidal Anti-inflammatory Drug [EPC] 2087 0.0022
96 Cardiac Glycoside [EPC] 138 0.0021
97 Non-Standardized Food Allergenic Extract [EPC] 29 0.0021
98 Expectorant [EPC] 323 0.0021
99 beta Lactamase Inhibitor [EPC] 8 0.0021
100 Cholinergic Muscarinic Antagonist [EPC] 66 0.0021
101 Oxazolidinone Antibacterial [EPC] 44 0.0021
102 Platelet Aggregation Inhibitor [EPC] 1026 0.0020
103 Dietary Cholesterol Absorption Inhibitor [EPC] 136 0.0020
104 Carbamoyl Phosphate Synthetase 1 Activator [EPC] 1 0.0020
105 beta-Adrenergic Blocker [EPC] 528 0.0020
106 Vitamin C [EPC] 532 0.0020
107 Vitamin B12 [EPC] 535 0.0020
108 Fluoroquinolone Antibacterial [EPC] 202 0.0020
109 Antimycobacterial [EPC] 30 0.0020
110 Antiparasitic [EPC] 9 0.0020
111 Vitamin D [EPC] 489 0.0020
112 Prostaglandin E1 Analog [EPC] 29 0.0019
113 Pediculicide [EPC] 9 0.0019
114 Sulfone [EPC] 15 0.0019
115 Phenothiazine [EPC] 41 0.0018
116 Amide Local Anesthetic [EPC] 112 0.0018
117 Thiazide Diuretic [EPC] 337 0.0018
118 Aluminum Complex [EPC] 34 0.0018
119 Dihydropyridine Calcium Channel Blocker [EPC] 453 0.0018
120 Calcitonin [EPC] 5 0.0018
121 Dihydrofolate Reductase Inhibitor Antibacterial [EPC] 131 0.0017
122 Oxytocic [EPC] 4 0.0017
123 Interleukin-17 Receptor A Antagonist [EPC] 2 0.0017
124 Provitamin D2 Compound [EPC] 502 0.0017
125 Aldosterone Antagonist [EPC] 196 0.0017
126 Nitrofuran Antibacterial [EPC] 33 0.0016
127 Sulfonylurea [EPC] 211 0.0016
128 Calcitonin Gene-related Peptide Antagonist [EPC] 4 0.0016
129 Tetracycline-class Drug [EPC] 77 0.0016
130 Nitroimidazole Antimicrobial [EPC] 87 0.0016
131 Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 75 0.0016
132 Glycopeptide Antibacterial [EPC] 77 0.0016
133 Loop Diuretic [EPC] 572 0.0016
134 Bile Acid [EPC] 23 0.0016
135 Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 76 0.0016
136 Azole Antifungal [EPC] 186 0.0016
137 Phosphodiesterase 3 Inhibitor [EPC] 8 0.0016
138 Blood Viscosity Reducer [EPC] 5 0.0016
139 Interferon gamma [EPC] 2 0.0015
140 Antiarrhythmic [EPC] 114 0.0015
141 beta3-Adrenergic Agonist [EPC] 43 0.0015
142 alpha-Hydroxy Acid [EPC] 2 0.0015
143 Estrogen [EPC] 239 0.0015
144 Folate Analog [EPC] 1 0.0015
145 CCR5 Co-receptor Antagonist [EPC] 3 0.0015
146 Opioid Antagonist [EPC] 1 0.0015
147 Xanthine Oxidase Inhibitor [EPC] 201 0.0014
148 Lincosamide Antibacterial [EPC] 35 0.0014
149 alpha-Adrenergic Blocker [EPC] 166 0.0014
150 Corticosteroid [EPC] 1382 0.0014
151 Retinoid [EPC] 317 0.0014
152 Pleuromutilin Antibacterial [EPC] 1 0.0014
153 Chloride Channel Activator [EPC] 11 0.0014
154 Progesterone [EPC] 22 0.0014
155 Thiazide-like Diuretic [EPC] 46 0.0014
156 Non-narcotic Antitussive [EPC] 16 0.0014
157 Parenteral Iron Replacement [EPC] 14 0.0014
158 Progestin Antagonist [EPC] 5 0.0014
159 Protease Inhibitor [EPC] 56 0.0014
160 Progestin [EPC] 331 0.0013
161 Bismuth [EPC] 6 0.0013
162 Plasma Kallikrein Inhibitor [EPC] 4 0.0013
163 Angiotensin 2 Receptor Blocker [EPC] 362 0.0013
164 Quinolone Antimicrobial [EPC] 10 0.0013
165 Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 112 0.0013
166 Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 114 0.0013
167 Sulfonamide Antibacterial [EPC] 4 0.0013
168 Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor [EPC] 64 0.0013
169 Potassium-sparing Diuretic [EPC] 21 0.0013
170 Serotonin-3 Receptor Antagonist [EPC] 114 0.0013
171 Insulin [EPC] 59 0.0013
172 Catecholamine [EPC] 69 0.0012
173 alpha-Adrenergic Agonist [EPC] 60 0.0012
174 Calcium [EPC] 148 0.0012
175 Polyene Antifungal [EPC] 42 0.0012
176 Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 137 0.0012
177 Hydrolytic Lysosomal Glucocerebroside-specific Enzyme [EPC] 7 0.0012
178 Insulin Analog [EPC] 440 0.0012
179 Cytochrome P450 3A Inhibitor [EPC] 64 0.0012
180 Interleukin-5 Antagonist [EPC] 32 0.0011
181 Prostaglandin Analog [EPC] 89 0.0011
182 Anti-IgE [EPC] 62 0.0011
183 Lipid-based Polyene Antifungal [EPC] 15 0.0011
184 Hydrolytic Lysosomal Neutral Glycosphingolipid-specific Enzyme [EPC] 8 0.0011
185 Melanin Synthesis Inhibitor [EPC] 1 0.0011
186 Vitamin K [EPC] 7 0.0011
187 Lipid Emulsion [EPC] 2 0.0011
188 Histamine-2 Receptor Antagonist [EPC] 303 0.0011
189 Uric Acid-specific Enzyme [EPC] 2 0.0011
190 Phosphodiesterase 5 Inhibitor [EPC] 109 0.0010
191 Adenosine Triphosphate-Citrate Lyase Inhibitor [EPC] 1 0.0010
192 Adenosine Receptor Agonist [EPC] 6 0.0010
193 Dihydrofolate Reductase Inhibitor Antimalarial [EPC] 1 0.0010
194 Intestinal Lipase Inhibitor [EPC] 24 0.0010
195 Thyroid Hormone Synthesis Inhibitor [EPC] 6 0.0010
196 Interferon beta [EPC] 189 0.0010
197 B Lymphocyte Stimulator-specific Inhibitor [EPC] 18 0.0010
198 Hepatitis C Virus NS5A Inhibitor [EPC] 41 0.0009
199 RNA Synthetase Inhibitor Antibacterial [EPC] 8 0.0009
200 Anti-coagulant [EPC] 5 0.0009
201 Alkaloid [EPC] 19 0.0009
202 Substance P/Neurokinin-1 Receptor Antagonist [EPC] 13 0.0009
203 Androgen Receptor Inhibitor [EPC] 53 0.0008
204 Arteriolar Vasodilator [EPC] 24 0.0008
205 Human Immunoglobulin G [EPC] 6 0.0008
206 Vitamin D3 Analog [EPC] 12 0.0008
207 Aromatase Inhibitor [EPC] 63 0.0007
208 Hepatitis C Virus NS3/4A Protease Inhibitor [EPC] 11 0.0007
209 Radioactive Diagnostic Agent [EPC] 1 0.0007
210 CD52-directed Cytolytic Antibody [EPC] 12 0.0007
211 Paramagnetic Contrast Agent [EPC] 3 0.0007
212 P2Y12 Platelet Inhibitor [EPC] 18 0.0007
213 Calcineurin Inhibitor Immunosuppressant [EPC] 60 0.0007
214 Dipeptidyl Peptidase 4 Inhibitor [EPC] 11 0.0007
215 Rifamycin Antibacterial [EPC] 16 0.0007
216 Purine Antimetabolite [EPC] 50 0.0007
217 Iron Chelator [EPC] 18 0.0007
218 Bile Acid Sequestrant [EPC] 6 0.0007
219 Vitamin D2 Analog [EPC] 10 0.0007
220 Anti-anginal [EPC] 11 0.0006
221 Sodium-Glucose Cotransporter 2 Inhibitor [EPC] 25 0.0006
222 Aminoglycoside Antibacterial [EPC] 21 0.0006
223 Radiographic Contrast Agent [EPC] 11 0.0006
224 Nuclear Export Inhibitor [EPC] 3 0.0006
225 Folate Analog Metabolic Inhibitor [EPC] 205 0.0006
226 Antiseptic [EPC] 2 0.0006
227 Prostacyclin Receptor Agonist [EPC] 11 0.0006
228 Antisense Oligonucleotide [EPC] 4 0.0006
229 Pyrimidine Synthesis Inhibitor [EPC] 23 0.0006
230 Antimetabolite Immunosuppressant [EPC] 6 0.0005
231 Guanylate Cyclase-C Agonist [EPC] 11 0.0005
232 Potassium Channel Blocker [EPC] 37 0.0005
233 Integrin Receptor Antagonist [EPC] 118 0.0005
234 Kinase Inhibitor [EPC] 227 0.0005
235 CD20-directed Cytolytic Antibody [EPC] 110 0.0005
236 CD38-directed Cytolytic Antibody [EPC] 14 0.0005
237 Asparagine-specific Enzyme [EPC] 5 0.0005
238 Factor Xa Inhibitor [EPC] 181 0.0005
239 CD30-directed Immunoconjugate [EPC] 3 0.0005
240 Vitamin D Analog [EPC] 8 0.0004
241 Copper-containing Intrauterine Device [EPC] 16 0.0004
242 Glinide [EPC] 3 0.0004
243 GLP-2 Analog [EPC] 4 0.0004
244 Sphingosine 1-phosphate Receptor Modulator [EPC] 1 0.0004
245 Potassium Binder [EPC] 6 0.0004
246 Phenylalanine Metabolizing Enzyme [EPC] 2 0.0004
247 Platinum-based Drug [EPC] 81 0.0004
248 Calcitonin Gene-related Peptide Receptor Antagonist [EPC] 2 0.0004
249 Contrast Agent for Ultrasound Imaging [EPC] 2 0.0004
250 Rifamycin Antimycobacterial [EPC] 1 0.0004
251 Tissue-nonspecific Alkaline Phosphatase [EPC] 2 0.0004
252 Alkylating Drug [EPC] 75 0.0004
253 mu-Opioid Receptor Agonist [EPC] 1 0.0004
254 Aminosalicylate [EPC] 39 0.0004
255 Complement Inhibitor [EPC] 17 0.0004
256 Interleukin-2 Receptor Blocking Antibody [EPC] 3 0.0004
257 Farnesoid X Receptor Agonist [EPC] 2 0.0003
258 Topoisomerase Inhibitor [EPC] 18 0.0003
259 Phosphodiesterase 4 Inhibitor [EPC] 46 0.0003
260 Janus Kinase Inhibitor [EPC] 17 0.0003
261 GLP-1 Receptor Agonist [EPC] 66 0.0003
262 Antirheumatic Agent [EPC] 27 0.0003
263 Prostacycline [EPC] 3 0.0003
264 Erythropoiesis-stimulating Agent [EPC] 20 0.0003
265 Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC] 4 0.0003
266 Parathyroid Hormone Analog [EPC] 32 0.0003
267 Nucleoside Metabolic Inhibitor [EPC] 64 0.0003
268 Acetylcholine Release Inhibitor [EPC] 20 0.0003
269 Tumor Necrosis Factor Blocker [EPC] 226 0.0003
270 Prostacycline Vasodilator [EPC] 27 0.0003
271 alpha-Glucosidase Inhibitor [EPC] 1 0.0003
272 Gadolinium-based Contrast Agent [EPC] 1 0.0003
273 Epidermal Growth Factor Receptor Antagonist [EPC] 10 0.0003
274 Selective T Cell Costimulation Modulator [EPC] 27 0.0003
275 Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 7 0.0003
276 Soluble Guanylate Cyclase Stimulator [EPC] 6 0.0002
277 Proteasome Inhibitor [EPC] 22 0.0002
278 Interleukin-1 Receptor Antagonist [EPC] 3 0.0002
279 Thalidomide Analog [EPC] 97 0.0002
280 Interleukin-12 Antagonist [EPC] 18 0.0002
281 Pyridone [EPC] 8 0.0002
282 Programmed Death Receptor-1 Blocking Antibody [EPC] 33 0.0002
283 Endothelin Receptor Antagonist [EPC] 38 0.0002
284 Parathyroid Hormone [EPC] 1 0.0002
285 Vasopressin V2 Receptor Antagonist [EPC] 2 0.0002
286 SLAMF7-directed Immunostimulatory Antibody [EPC] 1 0.0002
287 Somatostatin Analog [EPC] 1 0.0002
288 Vascular Endothelial Growth Factor Inhibitor [EPC] 31 0.0002
289 Microtubule Inhibitor [EPC] 25 0.0002
290 CTLA-4-directed Blocking Antibody [EPC] 7 0.0002
291 RANK Ligand Inhibitor [EPC] 35 0.0002
292 Interleukin-6 Receptor Antagonist [EPC] 19 0.0002
293 Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 3 0.0002
294 BCL-2 Inhibitor [EPC] 7 0.0002
295 Interleukin-17A Antagonist [EPC] 28 0.0002
296 Interleukin-23 Antagonist [EPC] 22 0.0002
297 Echinocandin Antifungal [EPC] 1 0.0002
298 Estrogen Receptor Antagonist [EPC] 4 0.0002
299 Leukocyte Growth Factor [EPC] 19 0.0002
300 Thrombopoietin Receptor Agonist [EPC] 2 0.0002
301 PCSK9 Inhibitor [EPC] 17 0.0001
302 Interleukin-4 Receptor alpha Antagonist [EPC] 21 0.0001
303 Hedgehog Pathway Inhibitor [EPC] 1 0.0001
304 HER2/neu Receptor Antagonist [EPC] 6 0.0001
305 SARS-CoV-2 Nucleotide Analog RNA Polymerase Inhibitor [EPC] 1 0.0001
306 Lipopeptide Antibacterial [EPC] 1 0.0001
307 Parathyroid Hormone-Related Peptide Analog [EPC] 1 0.0001