Drug Side Effects

BRCA2 GENE MUTATION

This adverse event was reported 51 times

These drugs are most commonly taken by patients reporting BRCA2 GENE MUTATION:

# Drug Count
0 OLAPARIB 16
1 CARBOPLATIN 15
2 GEMCITABINE HYDROCHLORIDE 11
3 BEVACIZUMAB 10
4 LETROZOLE 9
5 DENOSUMAB 8
6 GEMCITABINE 8
7 GOSERELIN 7
8 LETROZOLE TABLETS 7
9 PACLITAXEL 5
See all common drugs associated with BRCA2 GENE MUTATION

BRCA2 GENE MUTATION is most prevalent among patients taking these drugs:

# Drug Count Frequency
0 OLAPARIB 16 0.0017
1 STANDARDIZED SENNA CONCENTRATE AND DOCUSATE SODIUM 1 0.0010
2 GOSERELIN 7 0.0007
3 DHEA (DEHYDROEPIANDROSTERONE) 1 0.0005
4 RIBOCICLIB 5 0.0004
5 GEMCITABINE HYDROCHLORIDE 11 0.0003
6 PRASTERONE 1 0.0003
7 NIRAPARIB 4 0.0003
8 BICALUTAMIDE 3 0.0002
9 LETROZOLE TABLETS 7 0.0002
See all drugs enriched for association with BRCA2 GENE MUTATION

These drug classes are most commonly taken by patients reporting BRCA2 GENE MUTATION:

# Drug class Count
0 Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 19
1 Platinum-based Drug [EPC] 16
2 Aromatase Inhibitor [EPC] 13
3 Nucleoside Metabolic Inhibitor [EPC] 10
4 Vascular Endothelial Growth Factor Inhibitor [EPC] 10
5 RANK Ligand Inhibitor [EPC] 8
6 Kinase Inhibitor [EPC] 6
7 Microtubule Inhibitor [EPC] 6
8 Androgen Receptor Inhibitor [EPC] 4
9 Benzodiazepine [EPC] 4
See all common drug classes associated with BRCA2 GENE MUTATION

BRCA2 GENE MUTATION is most prevalent among patients taking these drug classes:

# Drug class Count Frequency
0 Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 19 0.0008
1 Aromatase Inhibitor [EPC] 13 0.0002
2 Estrogen Receptor Antagonist [EPC] 3 0.0001
3 Chloride Channel Activator [EPC] 1 0.0001
4 Bile Acid Sequestrant [EPC] 1 0.0001
5 Platinum-based Drug [EPC] 16 0.0001
6 Vascular Endothelial Growth Factor Inhibitor [EPC] 10 0.0001
7 Progesterone [EPC] 1 0.0001
8 Androgen Receptor Inhibitor [EPC] 4 0.0001
9 Microtubule Inhibitor [EPC] 6 0.0001
See all drug classes enriched for association with BRCA2 GENE MUTATION