INJECTION SITE SWELLING

INJECTION SITE SWELLING was reported 49868 times

INJECTION SITE SWELLING is most prevalent among patients taking these drug classes:

# Drug class Count Frequency
0 Melanocortin 4 Receptor Agonist [EPC] 3 0.1429
1 Cytolytic Agent [EPC] 242 0.1384
2 Phenylalanine Metabolizing Enzyme [EPC] 234 0.0711
3 Tissue-nonspecific Alkaline Phosphatase [EPC] 184 0.0393
4 Skin Test Antigen [EPC] 60 0.0316
5 Tumor Necrosis Factor Blocker [EPC] 23560 0.0311
6 Interleukin-1 Receptor Antagonist [EPC] 230 0.0235
7 PCSK9 Inhibitor [EPC] 1695 0.0170
8 Interleukin-4 Receptor alpha Antagonist [EPC] 1180 0.0164
9 Acetylcholine Release Inhibitor [EPC] 954 0.0160
10 Leptin Analog [EPC] 10 0.0137
11 Sclerosing Agent [EPC] 4 0.0134
12 Folate Analog Metabolic Inhibitor [EPC] 3257 0.0109
13 Interleukin-17A Antagonist [EPC] 1191 0.0104
14 GLP-1 Receptor Agonist [EPC] 1451 0.0082
15 Vitamin D [EPC] 1368 0.0076
16 Non-Standardized Insect Allergenic Extract [EPC] 29 0.0076
17 Antirheumatic Agent [EPC] 559 0.0075
18 Vitamin B12 [EPC] 1393 0.0072
19 Vitamin C [EPC] 1396 0.0072
20 Cholecystokinin Analog [EPC] 1 0.0072
21 Somatostatin Analog [EPC] 23 0.0069
22 Aminosalicylate [EPC] 558 0.0068
23 Plasma Kallikrein Inhibitor [EPC] 17 0.0066
24 Standardized Animal Hair Allergenic Extract [EPC] 3 0.0066
25 alpha-Adrenergic Agonist [EPC] 261 0.0064
26 Anti-IgE [EPC] 278 0.0062
27 Catecholamine [EPC] 262 0.0057
28 Interleukin-6 Receptor Antagonist [EPC] 409 0.0057
29 Endoglycosidase [EPC] 6 0.0054
30 Parathyroid Hormone Analog [EPC] 540 0.0052
31 Standardized Insect Venom Allergenic Extract [EPC] 29 0.0052
32 Serotonin-1b and Serotonin-1d Receptor Agonist [EPC] 167 0.0051
33 Vitamin B6 Analog [EPC] 1 0.0050
34 Gonadotropin [EPC] 5 0.0049
35 B Lymphocyte Stimulator-specific Inhibitor [EPC] 70 0.0049
36 Recombinant Human Growth Hormone [EPC] 50 0.0048
37 Vitamin D Analog [EPC] 16 0.0048
38 Ergot Derivative [EPC] 16 0.0047
39 Progesterone [EPC] 61 0.0046
40 Parathyroid Hormone-Related Peptide Analog [EPC] 45 0.0046
41 Non-Standardized Plant Allergenic Extract [EPC] 47 0.0045
42 Interferon beta [EPC] 849 0.0045
43 Barbiturate [EPC] 47 0.0044
44 Calcium [EPC] 461 0.0043
45 Phosphate Binder [EPC] 461 0.0042
46 GLP-2 Analog [EPC] 25 0.0042
47 Aldehyde Dehydrogenase Inhibitor [EPC] 5 0.0041
48 Non-Standardized Pollen Allergenic Extract [EPC] 3 0.0040
49 Bile Acid Sequestrant [EPC] 29 0.0040
50 Provitamin D2 Compound [EPC] 989 0.0040
51 Interleukin-6 Antagonist [EPC] 1 0.0040
52 Non-Standardized Food Allergenic Extract [EPC] 55 0.0037
53 Estrogen Receptor Antagonist [EPC] 64 0.0036
54 Leukotriene Receptor Antagonist [EPC] 47 0.0035
55 Surfactant [EPC] 3 0.0033
56 Interleukin-17 Receptor A Antagonist [EPC] 2 0.0031
57 Interleukin-5 Antagonist [EPC] 64 0.0031
58 Interleukin-5 Receptor alpha-directed Cytolytic Antibody [EPC] 18 0.0031
59 Purine Antimetabolite [EPC] 185 0.0030
60 Thyroid Stimulating Hormone [EPC] 2 0.0030
61 Parenteral Iron Replacement [EPC] 25 0.0030
62 Selective T Cell Costimulation Modulator [EPC] 250 0.0029
63 Insulin [EPC] 122 0.0029
64 Adenosine Receptor Agonist [EPC] 16 0.0028
65 Amide Local Anesthetic [EPC] 150 0.0027
66 Muscle Relaxant [EPC] 87 0.0027
67 Potassium-sparing Diuretic [EPC] 41 0.0026
68 Aluminum Complex [EPC] 44 0.0026
69 RNA Synthetase Inhibitor Antibacterial [EPC] 18 0.0025
70 Sulfone [EPC] 17 0.0025
71 Adrenocorticotropic Hormone [EPC] 3 0.0025
72 Parathyroid Hormone [EPC] 10 0.0025
73 Insulin Analog [EPC] 716 0.0024
74 l-Thyroxine [EPC] 285 0.0024
75 Thiazide Diuretic [EPC] 408 0.0024
76 Nonsteroidal Anti-inflammatory Drug [EPC] 2268 0.0024
77 Antiarrhythmic [EPC] 158 0.0024
78 Interleukin-23 Antagonist [EPC] 161 0.0023
79 Sulfonylurea [EPC] 288 0.0023
80 Sulfonamide Antibacterial [EPC] 6 0.0023
81 Histamine-1 Receptor Antagonist [EPC] 67 0.0023
82 Plasma Volume Expander [EPC] 1 0.0023
83 gamma-Aminobutyric Acid-ergic Agonist [EPC] 147 0.0023
84 Radiographic Contrast Agent [EPC] 36 0.0023
85 Estrogen [EPC] 322 0.0023
86 Corticosteroid [EPC] 1876 0.0022
87 Vitamin A [EPC] 10 0.0022
88 5-Lipoxygenase Inhibitor [EPC] 1 0.0021
89 Cephalosporin Antibacterial [EPC] 12 0.0021
90 Prostaglandin E1 Analog [EPC] 29 0.0021
91 Vitamin D3 Analog [EPC] 36 0.0020
92 Interleukin-12 Antagonist [EPC] 123 0.0020
93 Serotonin and Norepinephrine Reuptake Inhibitor [EPC] 86 0.0020
94 Sodium-Glucose Cotransporter 2 Inhibitor [EPC] 53 0.0020
95 Antimycobacterial [EPC] 27 0.0020
96 Proton Pump Inhibitor [EPC] 819 0.0020
97 Chloride Channel Activator [EPC] 14 0.0020
98 Lipid Emulsion [EPC] 3 0.0020
99 Photoactivated Radical Generator [EPC] 1 0.0020
100 Peroxisome Proliferator Receptor alpha Agonist [EPC] 118 0.0019
101 Radioactive Diagnostic Agent [EPC] 2 0.0019
102 alpha-Hydroxy Acid [EPC] 2 0.0019
103 Calcineurin Inhibitor Immunosuppressant [EPC] 131 0.0019
104 Dietary Cholesterol Absorption Inhibitor [EPC] 109 0.0018
105 Gadolinium-based Contrast Agent [EPC] 6 0.0018
106 Bismuth [EPC] 7 0.0018
107 alpha-Glucosidase Inhibitor [EPC] 6 0.0018
108 Methylxanthine [EPC] 275 0.0018
109 Tetracycline-class Drug [EPC] 71 0.0018
110 Glinide [EPC] 18 0.0018
111 gamma-Aminobutyric Acid A Receptor Agonist [EPC] 2 0.0017
112 Anti-epileptic Agent [EPC] 710 0.0017
113 Nitrofuran Antibacterial [EPC] 30 0.0017
114 Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC] 17 0.0017
115 HMG-CoA Reductase Inhibitor [EPC] 529 0.0017
116 Benzodiazepine [EPC] 876 0.0016
117 Soluble Guanylate Cyclase Stimulator [EPC] 32 0.0016
118 Central Nervous System Stimulant [EPC] 281 0.0016
119 Interferon gamma [EPC] 2 0.0016
120 beta-Adrenergic Blocker [EPC] 368 0.0016
121 Oxytocic [EPC] 3 0.0016
122 Lincosamide Antibacterial [EPC] 33 0.0016
123 Androgen [EPC] 58 0.0015
124 Influenza A M2 Protein Inhibitor [EPC] 15 0.0015
125 Sympathomimetic-like Agent [EPC] 39 0.0015
126 Prostacyclin Receptor Agonist [EPC] 23 0.0015
127 Blood Viscosity Reducer [EPC] 4 0.0015
128 Histamine-2 Receptor Antagonist [EPC] 366 0.0014
129 Contrast Agent for Ultrasound Imaging [EPC] 5 0.0014
130 Polymyxin-class Antibacterial [EPC] 1 0.0014
131 Dihydropyridine Calcium Channel Blocker [EPC] 62 0.0014
132 Guanylate Cyclase-C Agonist [EPC] 23 0.0014
133 Cholinergic Muscarinic Antagonist [EPC] 40 0.0014
134 Central alpha-2 Adrenergic Agonist [EPC] 58 0.0014
135 Thyroid Hormone Synthesis Inhibitor [EPC] 7 0.0014
136 Platelet Aggregation Inhibitor [EPC] 763 0.0014
137 Photoenhancer [EPC] 2 0.0014
138 Thiazide-like Diuretic [EPC] 39 0.0014
139 Antiseptic [EPC] 4 0.0014
140 Interferon alpha [EPC] 77 0.0014
141 Cannabinoid [EPC] 9 0.0013
142 Partial Opioid Agonist [EPC] 91 0.0013
143 Antihypoglycemic Agent [EPC] 3 0.0013
144 Vasopressin V2 Receptor Antagonist [EPC] 9 0.0013
145 Angiotensin Converting Enzyme Inhibitor [EPC] 131 0.0012
146 Potassium Channel Blocker [EPC] 78 0.0012
147 Phosphodiesterase 5 Inhibitor [EPC] 113 0.0012
148 Phosphodiesterase 4 Inhibitor [EPC] 13 0.0012
149 Dipeptidyl Peptidase 4 Inhibitor [EPC] 15 0.0012
150 Aldosterone Antagonist [EPC] 115 0.0012
151 Angiotensin 2 Receptor Blocker [EPC] 257 0.0011
152 Copper-containing Intrauterine Device [EPC] 29 0.0011
153 CCR5 Co-receptor Antagonist [EPC] 2 0.0011
154 Phosphodiesterase 3 Inhibitor [EPC] 5 0.0011
155 Non-Standardized Chemical Allergen [EPC] 24 0.0010
156 Bile Acid [EPC] 11 0.0010
157 Nitroimidazole Antimicrobial [EPC] 48 0.0010
158 Nitrate Vasodilator [EPC] 70 0.0010
159 Nucleoside Analog Antiviral [EPC] 88 0.0010
160 General Anesthetic [EPC] 28 0.0010
161 alpha-Adrenergic Blocker [EPC] 100 0.0010
162 Partial Cholinergic Nicotinic Agonist [EPC] 2 0.0010
163 RANK Ligand Inhibitor [EPC] 149 0.0010
164 Non-narcotic Antitussive [EPC] 12 0.0009
165 5-alpha Reductase Inhibitor [EPC] 48 0.0009
166 Opioid Agonist [EPC] 196 0.0009
167 Mood Stabilizer [EPC] 144 0.0009
168 Osmotic Diuretic [EPC] 3 0.0009
169 Xanthine Oxidase Inhibitor [EPC] 106 0.0009
170 Anti-anginal [EPC] 14 0.0009
171 Endothelin Receptor Antagonist [EPC] 124 0.0008
172 Non-Standardized Fungal Allergenic Extract [EPC] 1 0.0008
173 Monoamine Oxidase Inhibitor [EPC] 2 0.0008
174 Loop Diuretic [EPC] 268 0.0008
175 Polyene Antifungal [EPC] 24 0.0008
176 Nicotinic Acid [EPC] 36 0.0008
177 Pyrethroid [EPC] 1 0.0008
178 Osmotic Laxative [EPC] 123 0.0008
179 Estrogen Agonist/Antagonist [EPC] 2 0.0008
180 Androgen Receptor Inhibitor [EPC] 45 0.0008
181 Live Attenuated Bacillus Calmette-Guerin Immunotherapy [EPC] 1 0.0008
182 Antisense Oligonucleotide [EPC] 4 0.0008
183 Hydrolytic Lysosomal Glucocerebroside-specific Enzyme [EPC] 4 0.0008
184 Azole Antifungal [EPC] 78 0.0008
185 Serotonin-3 Receptor Antagonist [EPC] 55 0.0008
186 Dihydrofolate Reductase Inhibitor Antibacterial [EPC] 48 0.0007
187 Proteasome Inhibitor [EPC] 55 0.0007
188 Prostaglandin Analog [EPC] 51 0.0007
189 Carbonic Anhydrase Inhibitor [EPC] 10 0.0007
190 Histamine-1 Receptor Inhibitor [EPC] 2 0.0007
191 Anticholinergic [EPC] 7 0.0007
192 Uric Acid-specific Enzyme [EPC] 1 0.0007
193 Aromatic Amino Acid Decarboxylation Inhibitor [EPC] 23 0.0006
194 Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 45 0.0006
195 Benzothiazole [EPC] 1 0.0006
196 Antimalarial [EPC] 6 0.0006
197 Erythropoiesis-stimulating Agent [EPC] 44 0.0006
198 Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 43 0.0006
199 Complement Inhibitor [EPC] 27 0.0006
200 Quinolone Antimicrobial [EPC] 56 0.0006
201 Aromatic Amino Acid [EPC] 24 0.0006
202 CD20-directed Cytolytic Antibody [EPC] 85 0.0006
203 Leukocyte Growth Factor [EPC] 55 0.0006
204 CD30-directed Immunoconjugate [EPC] 3 0.0006
205 Carnitine Analog [EPC] 1 0.0006
206 beta Lactamase Inhibitor [EPC] 2 0.0006
207 Antiprotozoal [EPC] 4 0.0005
208 Macrolide Antimicrobial [EPC] 25 0.0005
209 Vitamin K [EPC] 3 0.0005
210 Rifamycin Antimycobacterial [EPC] 1 0.0005
211 Actinomycin [EPC] 1 0.0005
212 beta3-Adrenergic Agonist [EPC] 12 0.0005
213 Cardiac Glycoside [EPC] 31 0.0005
214 CD52-directed Cytolytic Antibody [EPC] 6 0.0005
215 Prostacycline Vasodilator [EPC] 23 0.0005
216 Aminoglycoside Antibacterial [EPC] 13 0.0005
217 Stimulant Laxative [EPC] 4 0.0004
218 P2Y12 Platelet Inhibitor [EPC] 10 0.0004
219 mu-Opioid Receptor Agonist [EPC] 1 0.0004
220 Catechol-O-Methyltransferase Inhibitor [EPC] 4 0.0004
221 Antidote [EPC] 3 0.0004
222 Aromatase Inhibitor [EPC] 29 0.0004
223 Melatonin Receptor Agonist [EPC] 4 0.0004
224 Atypical Antipsychotic [EPC] 126 0.0004
225 Nucleoside Metabolic Inhibitor [EPC] 72 0.0004
226 Factor Xa Inhibitor [EPC] 114 0.0004
227 Calcitonin [EPC] 1 0.0004
228 Antifibrinolytic Agent [EPC] 2 0.0003
229 Sigma-1 Agonist [EPC] 2 0.0003
230 Retinoid [EPC] 71 0.0003
231 Prostacycline [EPC] 3 0.0003
232 Hydrolytic Lysosomal Neutral Glycosphingolipid-specific Enzyme [EPC] 2 0.0003
233 Phenothiazine [EPC] 7 0.0003
234 Janus Kinase Inhibitor [EPC] 1 0.0003
235 Lipopeptide Antibacterial [EPC] 3 0.0003
236 Cholinesterase Inhibitor [EPC] 4 0.0003
237 Protease Inhibitor [EPC] 11 0.0003
238 Orexin Receptor Antagonist [EPC] 3 0.0003
239 CD38-directed Cytolytic Antibody [EPC] 5 0.0003
240 Rifamycin Antibacterial [EPC] 5 0.0003
241 Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 12 0.0003
242 Cytochrome P450 3A Inhibitor [EPC] 14 0.0003
243 Progestin [EPC] 64 0.0003
244 Alkylating Drug [EPC] 43 0.0003
245 Antimetabolite Immunosuppressant [EPC] 2 0.0003
246 Antiparasitic [EPC] 1 0.0003
247 Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 26 0.0003
248 Pediculicide [EPC] 1 0.0003
249 Serotonin-4 Receptor Agonist [EPC] 1 0.0003
250 Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor [EPC] 12 0.0002
251 Substance P/Neurokinin-1 Receptor Antagonist [EPC] 3 0.0002
252 Lymphocyte Function-Associated Antigen-1 Antagonist [EPC] 2 0.0002
253 Dopamine-2 Receptor Antagonist [EPC] 1 0.0002
254 Cholinergic Nicotinic Agonist [EPC] 11 0.0002
255 Recombinant Human Deoxyribonuclease 1 [EPC] 3 0.0002
256 Glycopeptide Antibacterial [EPC] 8 0.0002
257 HER2/neu Receptor Antagonist [EPC] 9 0.0002
258 Kinase Inhibitor [EPC] 65 0.0002
259 Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 8 0.0002
260 Vascular Endothelial Growth Factor Inhibitor [EPC] 23 0.0002
261 Pyrimidine Synthesis Inhibitor [EPC] 6 0.0002
262 Thrombopoietin Receptor Agonist [EPC] 2 0.0002
263 Oxazolidinone Antibacterial [EPC] 3 0.0002
264 Immunoglobulin G [EPC] 1 0.0002
265 Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 2 0.0002
266 SARS-CoV-2 Nucleotide Analog RNA Polymerase Inhibitor [EPC] 1 0.0002
267 Vesicular Monoamine Transporter 2 Inhibitor [EPC] 1 0.0001
268 Programmed Death Ligand-1 Blocker [EPC] 1 0.0001
269 Integrin Receptor Antagonist [EPC] 27 0.0001
270 Platinum-based Drug [EPC] 21 0.0001
271 Arteriolar Vasodilator [EPC] 3 0.0001
272 Asparagine-specific Enzyme [EPC] 1 0.0001
273 Typical Antipsychotic [EPC] 2 0.0001
274 Thalidomide Analog [EPC] 32 0.0001
275 Microtubule Inhibitor [EPC] 9 0.0001
276 Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] 1 0.0001
277 Programmed Death Receptor-1 Blocking Antibody [EPC] 8 0.0001
278 Epidermal Growth Factor Receptor Antagonist [EPC] 2 0.0001
279 Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 1 0.0001
280 BCL-2 Inhibitor [EPC] 1 0.0000
281 Hepatitis C Virus NS5A Inhibitor [EPC] 2 0.0000
282 Iron Chelator [EPC] 1 0.0000
283 Topoisomerase Inhibitor [EPC] 1 0.0000