RHEUMATOID ARTHRITIS

RHEUMATOID ARTHRITIS was reported 91610 times

RHEUMATOID ARTHRITIS is most prevalent among patients taking these drug classes:

# Drug class Count Frequency
0 Antirheumatic Agent [EPC] 21520 0.2404
1 Interleukin-6 Receptor Antagonist [EPC] 19649 0.1960
2 Selective T Cell Costimulation Modulator [EPC] 19571 0.1772
3 Aminosalicylate [EPC] 16301 0.1534
4 Interleukin-1 Receptor Antagonist [EPC] 1408 0.1081
5 Folate Analog Metabolic Inhibitor [EPC] 33240 0.0933
6 CD20-directed Cytolytic Antibody [EPC] 15936 0.0690
7 Tumor Necrosis Factor Blocker [EPC] 51110 0.0586
8 Vitamin D [EPC] 14401 0.0559
9 Vitamin B12 [EPC] 14481 0.0526
10 Prostaglandin E1 Analog [EPC] 788 0.0512
11 Vitamin C [EPC] 15070 0.0457
12 Standardized Chemical Allergen [EPC] 2624 0.0421
13 Histamine-1 Receptor Antagonist [EPC] 1520 0.0391
14 Purine Antimetabolite [EPC] 2590 0.0341
15 Interleukin-12 Antagonist [EPC] 2656 0.0330
16 Cannabinoid [EPC] 259 0.0316
17 Progesterone [EPC] 410 0.0248
18 Corticosteroid [EPC] 24390 0.0241
19 Endoglycosidase [EPC] 72 0.0240
20 Janus Kinase Inhibitor [EPC] 2242 0.0239
21 Expectorant [EPC] 3379 0.0211
22 Partial Opioid Agonist/Antagonist [EPC] 1 0.0208
23 Interleukin-23 Antagonist [EPC] 2736 0.0204
24 Calcium [EPC] 2367 0.0188
25 l-Triiodothyronine [EPC] 1 0.0185
26 Opioid Agonist [EPC] 4627 0.0185
27 Adrenocorticotropic Hormone [EPC] 17 0.0184
28 Non-Standardized Pollen Allergenic Extract [EPC] 6 0.0182
29 Alkaloid [EPC] 408 0.0177
30 Human Immunoglobulin G [EPC] 171 0.0177
31 Angiotensin Converting Enzyme Inhibitor [EPC] 2195 0.0176
32 Nonsteroidal Anti-inflammatory Drug [EPC] 17039 0.0171
33 Provitamin D2 Compound [EPC] 4448 0.0146
34 Interleukin-17A Antagonist [EPC] 2262 0.0142
35 Tetracycline-class Drug [EPC] 709 0.0139
36 Methylxanthine [EPC] 588 0.0137
37 Calcineurin Inhibitor Immunosuppressant [EPC] 1191 0.0130
38 Human Immunoglobulin [EPC] 1 0.0120
39 Bismuth [EPC] 57 0.0120
40 Substance P/Neurokinin-1 Receptor Antagonist [EPC] 182 0.0115
41 Dihydrofolate Reductase Inhibitor Antibacterial [EPC] 795 0.0102
42 Thyroid Stimulating Hormone [EPC] 8 0.0099
43 Phosphodiesterase 4 Inhibitor [EPC] 1429 0.0099
44 Leukotriene Receptor Antagonist [EPC] 175 0.0092
45 beta Lactamase Inhibitor [EPC] 35 0.0089
46 Central Nervous System Stimulant [EPC] 602 0.0089
47 Thiazide Diuretic [EPC] 1711 0.0089
48 Sulfonamide Antibacterial [EPC] 28 0.0086
49 Central alpha-2 Adrenergic Agonist [EPC] 417 0.0086
50 Muscle Relaxant [EPC] 317 0.0082
51 Potassium-sparing Diuretic [EPC] 136 0.0081
52 Proton Pump Inhibitor [EPC] 3874 0.0080
53 Non-Standardized Insect Allergenic Extract [EPC] 32 0.0079
54 gamma-Aminobutyric Acid-ergic Agonist [EPC] 597 0.0078
55 Serotonin Reuptake Inhibitor [EPC] 566 0.0078
56 Aluminum Complex [EPC] 152 0.0077
57 Calcitonin [EPC] 22 0.0076
58 l-Thyroxine [EPC] 1143 0.0075
59 alpha-Hydroxy Acid [EPC] 10 0.0070
60 Antidiarrheal [EPC] 2 0.0069
61 Standardized Insect Venom Allergenic Extract [EPC] 36 0.0069
62 Vitamin A [EPC] 369 0.0067
63 Diagnostic Dye [EPC] 1 0.0065
64 RNA Synthetase Inhibitor Antibacterial [EPC] 63 0.0065
65 Estrogen [EPC] 1055 0.0064
66 Melanin Synthesis Inhibitor [EPC] 6 0.0064
67 Vitamin B6 Analog [EPC] 305 0.0061
68 Nicotinic Acid [EPC] 364 0.0060
69 Serotonin-1b and Serotonin-1d Receptor Agonist [EPC] 225 0.0059
70 Dihydropyridine Calcium Channel Blocker [EPC] 1553 0.0058
71 Barbiturate [EPC] 61 0.0058
72 Macrolide Antimicrobial [EPC] 249 0.0057
73 Benzodiazepine [EPC] 3409 0.0056
74 Non-Standardized Food Allergenic Extract [EPC] 98 0.0056
75 Antidote [EPC] 327 0.0055
76 Antimycobacterial [EPC] 87 0.0055
77 Non-Standardized Plant Allergenic Extract [EPC] 53 0.0053
78 Lincosamide Antibacterial [EPC] 135 0.0052
79 beta-Adrenergic Blocker [EPC] 1404 0.0052
80 Xanthine Oxidase Inhibitor [EPC] 746 0.0051
81 HMG-CoA Reductase Inhibitor [EPC] 1866 0.0051
82 Anthelmintic [EPC] 12 0.0050
83 Interleukin-5 Antagonist [EPC] 153 0.0050
84 Amide Local Anesthetic [EPC] 327 0.0050
85 Platelet Aggregation Inhibitor [EPC] 2555 0.0049
86 Thiazide-like Diuretic [EPC] 168 0.0049
87 Nitrofuran Antibacterial [EPC] 102 0.0048
88 Angiotensin 2 Receptor Blocker [EPC] 1395 0.0048
89 Cephalosporin Antibacterial [EPC] 33 0.0048
90 Non-Standardized Fungal Allergenic Extract [EPC] 16 0.0047
91 Antiarrhythmic [EPC] 350 0.0045
92 Cholinergic Muscarinic Antagonist [EPC] 147 0.0045
93 Dietary Cholesterol Absorption Inhibitor [EPC] 315 0.0045
94 RANK Ligand Inhibitor [EPC] 786 0.0045
95 Phenothiazine [EPC] 100 0.0043
96 Nitrate Vasodilator [EPC] 317 0.0042
97 Pyruvate Kinase Activator [EPC] 1 0.0041
98 Fluoroquinolone Antibacterial [EPC] 436 0.0041
99 Blood Viscosity Reducer [EPC] 14 0.0041
100 Loop Diuretic [EPC] 1518 0.0041
101 Live Attenuated Bacillus Calmette-Guerin Immunotherapy [EPC] 6 0.0040
102 Parathyroid Hormone Analog [EPC] 422 0.0040
103 beta3-Adrenergic Agonist [EPC] 122 0.0039
104 Parenteral Iron Replacement [EPC] 41 0.0038
105 Dopamine and Norepinephrine Reuptake Inhibitor [EPC] 9 0.0038
106 Bile Acid Sequestrant [EPC] 36 0.0038
107 Non-narcotic Antitussive [EPC] 45 0.0037
108 Nitroimidazole Antimicrobial [EPC] 208 0.0037
109 Histamine-2 Receptor Antagonist [EPC] 1055 0.0037
110 Sulfone [EPC] 30 0.0036
111 Anti-IgE [EPC] 203 0.0036
112 Chloride Channel Activator [EPC] 29 0.0036
113 Programmed Death Receptor-1 Blocking Antibody [EPC] 554 0.0035
114 Peroxisome Proliferator Receptor alpha Agonist [EPC] 238 0.0035
115 Serotonin and Norepinephrine Reuptake Inhibitor [EPC] 8 0.0034
116 Sulfonylurea [EPC] 382 0.0034
117 B Lymphocyte Stimulator-specific Inhibitor [EPC] 67 0.0033
118 Photoactivated Radical Generator [EPC] 2 0.0032
119 alpha-Adrenergic Agonist [EPC] 164 0.0032
120 Serotonin-3 Receptor Antagonist [EPC] 307 0.0032
121 Aldosterone Antagonist [EPC] 378 0.0032
122 Sympathomimetic-like Agent [EPC] 91 0.0031
123 Azole Antifungal [EPC] 387 0.0031
124 Antimetabolite Immunosuppressant [EPC] 38 0.0031
125 Prostacyclin Receptor Agonist [EPC] 62 0.0031
126 Rifamycin Antimycobacterial [EPC] 8 0.0031
127 Osmotic Laxative [EPC] 556 0.0031
128 Insulin Analog [EPC] 1194 0.0031
129 Prostaglandin Analog [EPC] 244 0.0030
130 Farnesoid X Receptor Agonist [EPC] 18 0.0030
131 Thyroid Hormone Synthesis Inhibitor [EPC] 20 0.0030
132 Phosphodiesterase 3 Inhibitor [EPC] 16 0.0030
133 Folate Analog [EPC] 2 0.0030
134 CTLA-4-directed Blocking Antibody [EPC] 100 0.0029
135 Aromatase Inhibitor [EPC] 253 0.0028
136 Catecholamine [EPC] 165 0.0028
137 Nonergot Dopamine Agonist [EPC] 65 0.0028
138 Opioid Antagonist [EPC] 2 0.0028
139 Polyene Antifungal [EPC] 100 0.0027
140 alpha-Adrenergic Blocker [EPC] 326 0.0027
141 Quinolone Antimicrobial [EPC] 22 0.0027
142 Vitamin D3 Analog [EPC] 47 0.0027
143 Glinide [EPC] 19 0.0027
144 Bile Acid [EPC] 41 0.0026
145 Cardiac Glycoside [EPC] 173 0.0026
146 P2Y12 Platelet Inhibitor [EPC] 254 0.0026
147 Insulin [EPC] 125 0.0026
148 Dipeptidyl Peptidase 4 Inhibitor [EPC] 44 0.0026
149 Stimulant Laxative [EPC] 29 0.0025
150 Sodium-Glucose Cotransporter 2 Inhibitor [EPC] 109 0.0025
151 Vitamin K [EPC] 16 0.0024
152 Interleukin-17 Receptor A Antagonist [EPC] 3 0.0024
153 Estrogen Agonist/Antagonist [EPC] 6 0.0024
154 Non-Standardized Chemical Allergen [EPC] 53 0.0023
155 Carbonic Anhydrase Inhibitor [EPC] 38 0.0023
156 Tricyclic Antidepressant [EPC] 1 0.0023
157 Atypical Antipsychotic [EPC] 1006 0.0023
158 Guanylate Cyclase-C Agonist [EPC] 48 0.0023
159 Pyrethroid [EPC] 3 0.0021
160 Reducing and Complexing Thiol [EPC] 4 0.0021
161 Aminoglycoside Antibacterial [EPC] 72 0.0021
162 5-alpha Reductase Inhibitor [EPC] 126 0.0021
163 Rifamycin Antibacterial [EPC] 51 0.0020
164 Programmed Death Ligand-1 Blocker [EPC] 23 0.0020
165 Parathyroid Hormone-Related Peptide Analog [EPC] 28 0.0019
166 Plasma Volume Expander [EPC] 1 0.0019
167 Antiparasitic [EPC] 9 0.0019
168 Glycopeptide Antibacterial [EPC] 96 0.0019
169 Lymphocyte Function-Associated Antigen-1 Antagonist [EPC] 25 0.0019
170 Pediculicide [EPC] 9 0.0018
171 Interferon beta [EPC] 359 0.0018
172 Hydrolytic Lysosomal Glucocerebroside-specific Enzyme [EPC] 11 0.0018
173 Factor Xa Inhibitor [EPC] 687 0.0018
174 Amyloid Beta-directed Antibody [EPC] 1 0.0018
175 5-Lipoxygenase Inhibitor [EPC] 1 0.0017
176 Anti-anginal [EPC] 30 0.0017
177 GLP-2 Analog [EPC] 17 0.0017
178 Anticholinergic [EPC] 22 0.0017
179 Adenosine Triphosphate-Citrate Lyase Inhibitor [EPC] 2 0.0017
180 Mood Stabilizer [EPC] 308 0.0017
181 Androgen [EPC] 70 0.0017
182 Sigma-1 Agonist [EPC] 11 0.0017
183 Oxytocic [EPC] 4 0.0016
184 Melatonin Receptor Agonist [EPC] 19 0.0016
185 Anti-epileptic Agent [EPC] 318 0.0016
186 Antifibrinolytic Agent [EPC] 12 0.0016
187 Progestin Antagonist [EPC] 6 0.0016
188 Soluble Guanylate Cyclase Stimulator [EPC] 40 0.0016
189 Interleukin-5 Receptor alpha-directed Cytolytic Antibody [EPC] 15 0.0015
190 Calcitonin Gene-related Peptide Receptor Antagonist [EPC] 9 0.0015
191 alpha-Glucosidase Inhibitor [EPC] 6 0.0015
192 Endothelin Receptor Antagonist [EPC] 263 0.0015
193 gamma-Aminobutyric Acid A Receptor Agonist [EPC] 2 0.0015
194 Pyrimidine Synthesis Inhibitor [EPC] 63 0.0015
195 Uric Acid-specific Enzyme [EPC] 3 0.0015
196 Antiseptic [EPC] 5 0.0015
197 Interferon alfa-2b [EPC] 1 0.0015
198 Phosphodiesterase 5 Inhibitor [EPC] 156 0.0014
199 Pleuromutilin Antibacterial [EPC] 1 0.0014
200 Tissue-nonspecific Alkaline Phosphatase [EPC] 7 0.0014
201 Gonadotropin [EPC] 2 0.0013
202 Integrin Receptor Antagonist [EPC] 300 0.0013
203 Pyridone [EPC] 48 0.0013
204 Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 122 0.0013
205 Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 117 0.0013
206 Partial Opioid Agonist [EPC] 103 0.0013
207 Interferon alpha [EPC] 72 0.0013
208 GLP-1 Receptor Agonist [EPC] 282 0.0012
209 CD52-directed Cytolytic Antibody [EPC] 21 0.0012
210 Acetylcholine Release Inhibitor [EPC] 91 0.0012
211 Osmotic Diuretic [EPC] 5 0.0012
212 Prostacycline Vasodilator [EPC] 124 0.0012
213 Aldehyde Dehydrogenase Inhibitor [EPC] 1 0.0012
214 Methylating Agent [EPC] 1 0.0011
215 Copper-containing Intrauterine Device [EPC] 41 0.0011
216 Prostacycline [EPC] 11 0.0011
217 Influenza A M2 Protein Inhibitor [EPC] 13 0.0011
218 Antiprotozoal [EPC] 10 0.0011
219 Somatostatin Analog [EPC] 5 0.0010
220 Tyrosine Kinase 2 Inhibitor [EPC] 1 0.0010
221 Estrogen Receptor Antagonist [EPC] 27 0.0010
222 Anti-coagulant [EPC] 6 0.0010
223 Ergot Derivative [EPC] 4 0.0010
224 Cardiac Myosin Inhibitor [EPC] 1 0.0010
225 Oxazolidinone Antibacterial [EPC] 22 0.0010
226 Antihypoglycemic Agent [EPC] 3 0.0010
227 Erythroid Maturation Agent [EPC] 1 0.0009
228 Dihydrofolate Reductase Inhibitor Antimalarial [EPC] 1 0.0009
229 Intestinal Lipase Inhibitor [EPC] 23 0.0009
230 General Anesthetic [EPC] 31 0.0009
231 Interleukin-4 Receptor alpha Antagonist [EPC] 170 0.0009
232 Kinase Inhibitor [EPC] 404 0.0009
233 Alkylating Drug [EPC] 173 0.0009
234 PCSK9 Inhibitor [EPC] 119 0.0009
235 Skin Test Antigen [EPC] 2 0.0009
236 Complement Inhibitor [EPC] 43 0.0009
237 Poly(ADP-Ribose) Polymerase Inhibitor [EPC] 25 0.0008
238 Aromatic Amino Acid [EPC] 42 0.0008
239 Retinoid [EPC] 182 0.0008
240 Erythropoiesis-stimulating Agent [EPC] 51 0.0008
241 mu-Opioid Receptor Agonist [EPC] 2 0.0008
242 Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor [EPC] 38 0.0007
243 Monoamine Oxidase Inhibitor [EPC] 2 0.0007
244 Nucleoside Analog Antiviral [EPC] 59 0.0007
245 Hepatitis C Virus NS3/4A Protease Inhibitor [EPC] 11 0.0007
246 Dopamine-2 Receptor Antagonist [EPC] 4 0.0007
247 Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 34 0.0007
248 Recombinant Human Growth Hormone [EPC] 9 0.0006
249 Aromatic Amino Acid Decarboxylation Inhibitor [EPC] 29 0.0006
250 Plasma Kallikrein Inhibitor [EPC] 2 0.0006
251 Calcitonin Gene-related Peptide Antagonist [EPC] 2 0.0006
252 Vitamin D Analog [EPC] 10 0.0006
253 Progestin [EPC] 150 0.0006
254 HER2/neu Receptor Antagonist [EPC] 34 0.0006
255 Cholinesterase Inhibitor [EPC] 9 0.0006
256 Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 69 0.0006
257 Macrolide Antibacterial [EPC] 1 0.0006
258 Hepatitis C Virus NS5A Inhibitor [EPC] 25 0.0005
259 Cholinergic Nicotinic Agonist [EPC] 30 0.0005
260 Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] 26 0.0005
261 Typical Antipsychotic [EPC] 11 0.0005
262 Adenosine Receptor Agonist [EPC] 3 0.0005
263 Platinum-based Drug [EPC] 95 0.0005
264 Human Platelet-derived Growth Factor [EPC] 1 0.0005
265 Monobactam Antibacterial [EPC] 1 0.0005
266 Parathyroid Hormone [EPC] 2 0.0005
267 Interleukin-2 Receptor Blocking Antibody [EPC] 4 0.0004
268 Cytochrome P450 3A Inhibitor [EPC] 25 0.0004
269 Vesicular Monoamine Transporter 2 Inhibitor [EPC] 3 0.0004
270 Orexin Receptor Antagonist [EPC] 6 0.0004
271 Lipid-based Polyene Antifungal [EPC] 6 0.0004
272 Catechol-O-Methyltransferase Inhibitor [EPC] 5 0.0004
273 Vascular Endothelial Growth Factor Inhibitor [EPC] 62 0.0004
274 Androgen Receptor Inhibitor [EPC] 26 0.0004
275 Hydrolytic Lysosomal Neutral Glycosphingolipid-specific Enzyme [EPC] 3 0.0004
276 Insulin-like Growth Factor-1 Receptor Inhibitor [EPC] 1 0.0004
277 Carnitine Analog [EPC] 1 0.0004
278 Phenylalanine Metabolizing Enzyme [EPC] 2 0.0004
279 Noncompetitive AMPA Glutamate Receptor Antagonist [EPC] 2 0.0004
280 Potassium Channel Blocker [EPC] 26 0.0004
281 Hedgehog Pathway Inhibitor [EPC] 3 0.0004
282 Iron Chelator [EPC] 10 0.0004
283 Topoisomerase Inhibitor [EPC] 21 0.0004
284 Vitamin D2 Analog [EPC] 5 0.0003
285 Thrombopoietin Receptor Agonist [EPC] 4 0.0003
286 Leukocyte Growth Factor [EPC] 37 0.0003
287 Sphingosine 1-phosphate Receptor Modulator [EPC] 3 0.0003
288 Microtubule Inhibitor [EPC] 35 0.0003
289 Antimalarial [EPC] 2 0.0003
290 Nucleoside Metabolic Inhibitor [EPC] 62 0.0003
291 Gadolinium-based Contrast Agent [EPC] 1 0.0003
292 Paramagnetic Contrast Agent [EPC] 1 0.0002
293 CD19-directed Chimeric Antigen Receptor [EPC] 2 0.0002
294 Thalidomide Analog [EPC] 93 0.0002
295 Arteriolar Vasodilator [EPC] 8 0.0002
296 Protease Inhibitor [EPC] 9 0.0002
297 Cystic Fibrosis Transmembrane Conductance Regulator Potentiator [EPC] 3 0.0002
298 Autologous Cellular Immunotherapy [EPC] 1 0.0002
299 Tetracycline-class Antibacterial [EPC] 1 0.0002
300 SARS-CoV-2 Nucleotide Analog RNA Polymerase Inhibitor [EPC] 2 0.0002
301 Lipopeptide Antibacterial [EPC] 2 0.0002
302 CD38-directed Cytolytic Antibody [EPC] 5 0.0002
303 Proteasome Inhibitor [EPC] 13 0.0001
304 BCL-2 Inhibitor [EPC] 5 0.0001
305 Recombinant Human Deoxyribonuclease 1 [EPC] 2 0.0001
306 Radiographic Contrast Agent [EPC] 2 0.0001
307 Vasopressin V2 Receptor Antagonist [EPC] 1 0.0001
308 Hemoglobin S Polymerization Inhibitor [EPC] 2 0.0001
309 Epidermal Growth Factor Receptor Antagonist [EPC] 3 0.0001
310 Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC] 1 0.0001