Drug Side Effects

ETANERCEPT

ETANERCEPT was reported 565414 times

ETANERCEPT is most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 INJECTION SITE RECALL REACTION 483 0.9699
1 HUMAN ANTICHIMERIC ANTIBODY POSITIVE 280 0.9272
2 ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE 3420 0.8913
3 RHEUMATOID FACTOR NEGATIVE 150 0.8772
4 SWOLLEN JOINT COUNT INCREASED 891 0.8510
5 RED BLOOD CELL SEDIMENTATION RATE 216 0.8340
6 ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY 177 0.8233
7 RHEUMATOID FACTOR POSITIVE 2804 0.8071
8 RED BLOOD CELL SEDIMENTATION RATE ABNORMAL 1634 0.7924
9 RHEUMATIC FEVER 1114 0.7774
10 PEMPHIGUS 6032 0.7595
11 C-REACTIVE PROTEIN ABNORMAL 2882 0.7365
12 INJECTION SITE MACULE 469 0.7031
13 HAND DEFORMITY 6053 0.6824
14 SYNOVITIS 8628 0.6547
15 DUODENAL ULCER PERFORATION 2259 0.6476
16 GRANULOMA SKIN 460 0.6452
17 DEEP VEIN THROMBOSIS POSTOPERATIVE 268 0.6036
18 INJECTION SITE WARMTH 10352 0.5772
19 JOINT DESTRUCTION 701 0.5443
20 SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE 1956 0.5375
21 JUVENILE ARTHRITIS 168 0.5122
22 ELBOW DEFORMITY 156 0.4937
23 RHEUMATOID NODULE 1209 0.4867
24 CONTRAINDICATED PRODUCT ADMINISTERED 11004 0.4862
25 BODY HEIGHT BELOW NORMAL 299 0.4862
26 BONE EROSION 1201 0.4851
27 RHEUMATOID ARTHRITIS 42754 0.4754
28 NODULE ON EXTREMITY 163 0.4711
29 BLOOD IRON ABNORMAL 359 0.4516
30 WRIST DEFORMITY 242 0.4490
31 INJECTION SITE HAEMATOMA 6052 0.4325
32 BLOOD PARATHYROID HORMONE DECREASED 547 0.4263
33 JUVENILE IDIOPATHIC ARTHRITIS 801 0.4238
34 MUSCLE INJURY 1974 0.4190
35 HELICOBACTER INFECTION 2491 0.4170
36 INJECTION SITE PRURITUS 21954 0.4104
37 INJECTION SITE ERYTHEMA 40817 0.4074
38 INJECTION SITE SWELLING 23128 0.3998
39 DRUG TOLERANCE DECREASED 729 0.3975
40 FINGER DEFORMITY 1405 0.3851
41 FOLLICULITIS 2121 0.3790
42 ENTHESOPATHY 463 0.3758
43 ANTIBIOTIC THERAPY 255 0.3669
44 INJECTION SITE REACTION 20224 0.3614
45 INJECTION SITE INDURATION 3954 0.3546
46 DISLOCATION OF VERTEBRA 312 0.3490
47 CHONDROLYSIS 157 0.3376
48 ADJUSTMENT DISORDER WITH DEPRESSED MOOD 257 0.3320
49 SERONEGATIVE ARTHRITIS 205 0.3317
50 RHEUMATOID LUNG 269 0.3289
51 GLOSSODYNIA 5481 0.3267
52 PERICARDITIS 3508 0.3253
53 INJECTION SITE IRRITATION 3358 0.3250
54 JOINT ARTHROPLASTY 480 0.3230
55 TRANSPLANT DYSFUNCTION 456 0.3218
56 ARTHRODESIS 268 0.3172
57 PANNICULITIS 594 0.3116
58 PSORIATIC ARTHROPATHY 8516 0.3105
59 RED BLOOD CELL SEDIMENTATION RATE INCREASED 2779 0.3099
60 INJECTION SITE RASH 7020 0.3083
61 INJECTION SITE DISCOLOURATION 2984 0.3026
62 SYSTEMIC LUPUS ERYTHEMATOSUS 7242 0.2987
63 X-RAY ABNORMAL 252 0.2972
64 FACET JOINT SYNDROME 247 0.2923
65 INJECTION SITE URTICARIA 5149 0.2855
66 BUNION 201 0.2796
67 GRIP STRENGTH DECREASED 1595 0.2767
68 RHEUMATOID FACTOR INCREASED 263 0.2700
69 JOINT WARMTH 280 0.2685
70 TUBERCULIN TEST POSITIVE 640 0.2656
71 DEAFNESS TRANSITORY 198 0.2651
72 ARTHROPATHY 12021 0.2648
73 THERAPEUTIC PRODUCT EFFECT DECREASED 8185 0.2633
74 TENOSYNOVITIS 625 0.2632
75 ANKYLOSING SPONDYLITIS 2298 0.2602
76 FOETAL MALFORMATION 232 0.2533
77 KNEE ARTHROPLASTY 3822 0.2527
78 INJECTION SITE PAIN 55992 0.2499
79 INJECTION SITE HYPERSENSITIVITY 480 0.2494
80 DACTYLITIS 178 0.2462
81 PARANASAL SINUS HYPERSECRETION 826 0.2445
82 WRIST SURGERY 169 0.2439
83 SYSTEMIC LUPUS ERYTHEMATOSUS RASH 166 0.2413
84 FOOT DEFORMITY 2140 0.2405
85 WOUND 4869 0.2401
86 RUBBER SENSITIVITY 267 0.2390
87 INJECTION SITE DISCOMFORT 1753 0.2379
88 LIMB DEFORMITY 339 0.2376
89 JOINT SWELLING 22455 0.2366
90 BONE CYST 194 0.2312
91 RETINITIS 150 0.2266
92 SKIN PLAQUE 1514 0.2232
93 INJECTION SITE BRUISING 13570 0.2225
94 HIP ARTHROPLASTY 2489 0.2225
95 DRUG EFFECT INCOMPLETE 8099 0.2224
96 PSORIASIS 23921 0.2220
97 JOINT STIFFNESS 4758 0.2208
98 FEAR OF INJECTION 1022 0.2185
99 MYCOBACTERIUM TUBERCULOSIS COMPLEX TEST POSITIVE 421 0.2155
100 JOINT EFFUSION 1236 0.2101
101 IRITIS 525 0.2087
102 JOINT RANGE OF MOTION DECREASED 1954 0.2063
103 PLEURAL FIBROSIS 198 0.2054
104 INJECTION SITE INFLAMMATION 784 0.2045
105 FOOT OPERATION 754 0.2036
106 DEMYELINATION 688 0.2021
107 DRUG INTOLERANCE 14605 0.1964
108 NODULE 2014 0.1910
109 LOCAL SWELLING 3317 0.1899
110 INJECTION SITE VESICLES 805 0.1875
111 CHONDROPATHY 457 0.1874
112 TREATMENT FAILURE 11346 0.1853
113 RESPIRATORY TRACT CONGESTION 2313 0.1851
114 OPEN WOUND 205 0.1830
115 ALANINE AMINOTRANSFERASE ABNORMAL 286 0.1830
116 SCLERITIS 218 0.1797
117 JOINT CREPITATION 354 0.1783
118 JOINT LOCK 426 0.1769
119 SINUSITIS 14699 0.1769
120 MUSCULOSKELETAL STIFFNESS 12618 0.1761
121 SACROILIITIS 257 0.1739
122 PUSTULAR PSORIASIS 470 0.1734
123 ANTIBODY TEST POSITIVE 257 0.1725
124 INCORRECT PRODUCT STORAGE 2259 0.1717
125 IMPAIRED HEALING 4396 0.1709
126 ANKLE OPERATION 177 0.1704
127 CONTRAST MEDIA ALLERGY 192 0.1701
128 FINE MOTOR SKILL DYSFUNCTION 364 0.1671
129 INJECTION SITE PARAESTHESIA 172 0.1641
130 ONYCHOMYCOSIS 508 0.1639
131 MOBILITY DECREASED 9253 0.1620
132 LOWER RESPIRATORY TRACT INFECTION 5318 0.1620
133 SPINAL FUSION SURGERY 485 0.1617
134 POLYARTHRITIS 624 0.1607
135 IRRITABLE BOWEL SYNDROME 2437 0.1568
136 FIBROMYALGIA 2874 0.1559
137 PERIPHERAL VENOUS DISEASE 282 0.1555
138 SINUS CONGESTION 1719 0.1551
139 BRONCHITIS CHRONIC 328 0.1536
140 LATENT TUBERCULOSIS 240 0.1518
141 SYNOVIAL CYST 598 0.1517
142 DECREASED IMMUNE RESPONSIVENESS 1039 0.1510
143 MUSCULOSKELETAL PAIN 7145 0.1493
144 SENSITIVITY TO WEATHER CHANGE 574 0.1493
145 THERAPEUTIC RESPONSE DECREASED 6985 0.1487
146 SINUS HEADACHE 774 0.1479
147 ARTHROPOD BITE 870 0.1463
148 MUSCULOSKELETAL DISORDER 2394 0.1457
149 DRUG EFFECT DECREASED 7691 0.1425
150 INJECTION SITE HAEMORRHAGE 8703 0.1419
151 PHARYNGITIS STREPTOCOCCAL 1173 0.1417
152 SWELLING 10553 0.1416
153 IRIDOCYCLITIS 314 0.1407
154 RHEUMATIC DISORDER 223 0.1399
155 ARTHRITIS INFECTIVE 503 0.1369
156 ROTATOR CUFF REPAIR 187 0.1368
157 TOOTH INFECTION 1429 0.1342
158 HEPATIC ENZYME INCREASED 7043 0.1341
159 ANIMAL BITE 277 0.1338
160 VIRAL UPPER RESPIRATORY TRACT INFECTION 564 0.1320
161 BURSITIS 1099 0.1320
162 LIMB OPERATION 441 0.1304
163 THERAPEUTIC RESPONSE DELAYED 300 0.1302
164 INJECTION SITE EXTRAVASATION 1522 0.1299
165 EXOSTOSIS 937 0.1293
166 ARTHRALGIA 41861 0.1293
167 OSTEOARTHRITIS 4367 0.1290
168 NASOPHARYNGITIS 18444 0.1287
169 ARTHROPOD STING 168 0.1284
170 UPPER RESPIRATORY TRACT CONGESTION 321 0.1283
171 C-REACTIVE PROTEIN INCREASED 3601 0.1274
172 SARCOIDOSIS 485 0.1268
173 INCREASED TENDENCY TO BRUISE 1002 0.1255
174 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 4119 0.1254
175 ARTHRITIS 7966 0.1251
176 INJECTION SITE MASS 3512 0.1232
177 WALKING AID USER 620 0.1230
178 NECK SURGERY 191 0.1218
179 INFLAMMATION 4697 0.1215
180 INTERVERTEBRAL DISCITIS 174 0.1205
181 ENDODONTIC PROCEDURE 251 0.1190
182 INFECTION SUSCEPTIBILITY INCREASED 198 0.1189
183 INDURATION 178 0.1185
184 LOCALISED INFECTION 2331 0.1185
185 EAR INFECTION 2366 0.1182
186 UPPER RESPIRATORY TRACT INFECTION 4338 0.1179
187 PULMONARY FIBROSIS 1663 0.1156
188 ONYCHOMADESIS 300 0.1156
189 WHEELCHAIR USER 420 0.1153
190 APPARENT DEATH 407 0.1135
191 SHOULDER OPERATION 324 0.1134
192 INJECTION SITE OEDEMA 157 0.1130
193 SKIN NECROSIS 501 0.1122
194 INCORRECT STORAGE OF DRUG 193 0.1116
195 UVEITIS 1080 0.1112
196 ADVERSE REACTION 1192 0.1112
197 LACERATION 1047 0.1111
198 FURUNCLE 727 0.1095
199 TENDERNESS 961 0.1090
200 KNEE OPERATION 742 0.1089
201 VULVOVAGINAL MYCOTIC INFECTION 366 0.1082
202 PNEUMONIA VIRAL 260 0.1078
203 ANTINUCLEAR ANTIBODY POSITIVE 305 0.1070
204 EAR PAIN 1684 0.1070
205 MACULE 238 0.1067
206 NAIL DISORDER 663 0.1065
207 DISCOMFORT 4726 0.1062
208 SCIATICA 1215 0.1055
209 THERAPY NON-RESPONDER 3180 0.1048
210 INFLAMMATORY MARKER INCREASED 371 0.1048
211 EAR CONGESTION 226 0.1046
212 HIP SURGERY 387 0.1033
213 PHARYNGOLARYNGEAL PAIN 547 0.1028
214 BRONCHITIS 6454 0.1026
215 THYROID NEOPLASM 268 0.1022
216 PERIPHERAL SWELLING 12119 0.1020
217 JOINT INJURY 1764 0.1018
218 IMMUNOSUPPRESSION 626 0.1017
219 NECK MASS 232 0.1017
220 DRUG EFFECT DELAYED 460 0.1013
221 PHARYNGITIS 1053 0.1008
222 BASAL CELL CARCINOMA 1268 0.1005
223 SPINAL COLUMN INJURY 183 0.1004
224 HERPES ZOSTER 4741 0.1004
225 INFECTION 11127 0.1001
226 TOOTH ABSCESS 877 0.1000
227 WOUND INFECTION 729 0.0999
228 INCORRECT DISPOSAL OF PRODUCT 173 0.0977
229 ARTHRITIS BACTERIAL 325 0.0972
230 JOINT DISLOCATION 810 0.0972
231 SKIN ULCER 2067 0.0967
232 IMMOBILE 347 0.0967
233 ORAL SURGERY 173 0.0966
234 SKIN PAPILLOMA 316 0.0965
235 PAIN IN EXTREMITY 23956 0.0964
236 ACCIDENTAL EXPOSURE TO PRODUCT 5606 0.0952
237 INFUSION RELATED REACTION 4612 0.0949
238 DIVERTICULITIS 2084 0.0937
239 TUBERCULOSIS 985 0.0933
240 LIVER FUNCTION TEST INCREASED 1386 0.0932
241 LARYNGITIS 784 0.0932
242 INJECTION SITE INJURY 296 0.0917
243 LYME DISEASE 243 0.0916
244 ILL-DEFINED DISORDER 3199 0.0908
245 POST PROCEDURAL INFECTION 562 0.0907
246 HEPATIC ENZYME ABNORMAL 360 0.0906
247 INCREASED UPPER AIRWAY SECRETION 424 0.0906
248 SPINAL OPERATION 712 0.0905
249 NO THERAPEUTIC RESPONSE 1102 0.0902
250 BLISTER 3921 0.0894
251 CUTANEOUS VASCULITIS 177 0.0893
252 LUPUS-LIKE SYNDROME 600 0.0877
253 INGROWING NAIL 170 0.0873
254 GAIT INABILITY 1895 0.0864
255 CYST 874 0.0861
256 NECK PAIN 3924 0.0860
257 INFLUENZA 7147 0.0857
258 SKIN INJURY 229 0.0854
259 COLITIS MICROSCOPIC 286 0.0851
260 SURGERY 3522 0.0848
261 DRUG ERUPTION 1152 0.0843
262 SPINAL PAIN 789 0.0841
263 DEFORMITY 704 0.0840
264 IMMUNE SYSTEM DISORDER 879 0.0839
265 STREPTOCOCCAL INFECTION 353 0.0838
266 MENISCUS INJURY 423 0.0836
267 LYMPHOMA 1088 0.0835
268 SPINAL COLUMN STENOSIS 393 0.0829
269 SPONDYLITIS 222 0.0827
270 CONTUSION 6391 0.0823
271 SKIN HAEMORRHAGE 778 0.0819
272 CONDITION AGGRAVATED 18088 0.0809
273 INFECTIOUS MONONUCLEOSIS 150 0.0805
274 TONSILLITIS 332 0.0802
275 AUTOIMMUNE DISORDER 483 0.0801
276 SECRETION DISCHARGE 722 0.0801
277 LIVER INJURY 1238 0.0801
278 CREPITATIONS 214 0.0800
279 SCRATCH 560 0.0800
280 OROPHARYNGEAL PAIN 5931 0.0799
281 CARPAL TUNNEL SYNDROME 918 0.0797
282 INTERCEPTED PRODUCT ADMINISTRATION ERROR 240 0.0796
283 ABDOMINAL DISCOMFORT 10516 0.0793
284 SPINAL DISORDER 620 0.0791
285 DISABILITY 1253 0.0787
286 SKIN MASS 397 0.0785
287 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 3821 0.0783
288 SPINAL STENOSIS 207 0.0781
289 GALLBLADDER OPERATION 241 0.0773
290 SINUS DISORDER 1242 0.0772
291 DRUG HYPERSENSITIVITY 12512 0.0766
292 PAIN 39445 0.0766
293 RHINORRHOEA 3806 0.0762
294 STOMATITIS 3619 0.0757
295 HYPERSENSITIVITY 11257 0.0746
296 STAPHYLOCOCCAL INFECTION 2106 0.0746
297 ULCER 981 0.0746
298 MENOPAUSE 149 0.0745
299 DEAFNESS NEUROSENSORY 189 0.0745
300 EYE INFECTION 629 0.0745
301 MONOCYTE COUNT INCREASED 209 0.0744
302 MUSCULOSKELETAL DISCOMFORT 1030 0.0739
303 EYE OPERATION 224 0.0738
304 PULMONARY MASS 853 0.0736
305 GASTROENTERITIS VIRAL 1027 0.0735
306 WEIGHT BEARING DIFFICULTY 166 0.0734
307 OVARIAN CYST 643 0.0734
308 TOOTH FRACTURE 678 0.0734
309 TOOTHACHE 1079 0.0731
310 INJURY ASSOCIATED WITH DEVICE 1065 0.0728
311 ALOPECIA 11941 0.0726
312 PLANTAR FASCIITIS 198 0.0724
313 SNEEZING 1241 0.0724
314 KIDNEY INFECTION 1139 0.0722
315 INJECTION SITE NODULE 676 0.0722
316 CATARACT OPERATION 344 0.0721
317 THERAPY INTERRUPTED 2322 0.0720
318 FUNGAL SKIN INFECTION 228 0.0719
319 EXCORIATION 181 0.0711
320 NASAL CONGESTION 3156 0.0706
321 ORAL INFECTION 228 0.0706
322 MASS 831 0.0706
323 PARANASAL SINUS DISCOMFORT 193 0.0705
324 RASH PRURITIC 2971 0.0705
325 MALIGNANT MELANOMA 783 0.0704
326 ULCERATIVE KERATITIS 154 0.0702
327 PRURITUS GENERALISED 1517 0.0700
328 HYPERCHOLESTEROLAEMIA 467 0.0698
329 OBESITY 836 0.0692
330 INTERVERTEBRAL DISC DISORDER 257 0.0690
331 MATERNAL EXPOSURE DURING PREGNANCY 4324 0.0687
332 GASTROINTESTINAL DISORDER 4120 0.0681
333 ROTATOR CUFF SYNDROME 738 0.0678
334 RESPIRATORY TRACT INFECTION 1326 0.0678
335 SKIN INFECTION 583 0.0678
336 INJECTION SITE INFECTION 182 0.0676
337 LOWER LIMB FRACTURE 964 0.0674
338 DRUG DOSE OMISSION 11165 0.0674
339 TRANSPLANT REJECTION 424 0.0672
340 DEVICE ISSUE 4124 0.0671
341 DRUG INEFFECTIVE 71207 0.0670
342 NIGHT SWEATS 1662 0.0665
343 LIGAMENT RUPTURE 243 0.0664
344 UPPER-AIRWAY COUGH SYNDROME 412 0.0656
345 INTERVERTEBRAL DISC PROTRUSION 1224 0.0656
346 HYPERKERATOSIS 295 0.0656
347 INCORRECT DOSE ADMINISTERED BY DEVICE 930 0.0656
348 TENDON DISORDER 359 0.0655
349 DRUG DOSE OMISSION BY DEVICE 1458 0.0654
350 PULMONARY TOXICITY 324 0.0653
351 INJECTION SITE PAPULE 248 0.0652
352 INTERVERTEBRAL DISC DEGENERATION 535 0.0652
353 TRIGGER FINGER 205 0.0649
354 TOOTH DISORDER 1228 0.0648
355 RASH ERYTHEMATOUS 2176 0.0645
356 DERMATITIS ALLERGIC 598 0.0642
357 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 9580 0.0640
358 GRANULOMA 180 0.0639
359 PAPULE 318 0.0637
360 BREAST CANCER STAGE III 286 0.0637
361 SPUTUM DISCOLOURED 473 0.0636
362 PLEURITIC PAIN 151 0.0634
363 ORAL HERPES 934 0.0632
364 LIP DRY 345 0.0628
365 CYSTITIS 1704 0.0628
366 UNEVALUABLE EVENT 4094 0.0625
367 PRODUCTIVE COUGH 2207 0.0623
368 LIVE BIRTH 357 0.0622
369 DRUG USE DISORDER 252 0.0618
370 IMMUNODEFICIENCY 627 0.0614
371 HYPERCALCAEMIA 615 0.0614
372 ADRENAL INSUFFICIENCY 495 0.0612
373 NERVE COMPRESSION 457 0.0612
374 LIMB DISCOMFORT 1537 0.0612
375 BLOOD CHOLESTEROL INCREASED 2271 0.0607
376 RASH PUSTULAR 398 0.0606
377 MATERNAL EXPOSURE TIMING UNSPECIFIED 158 0.0605
378 GASTRIC INFECTION 181 0.0599
379 DRUG TOLERANCE 246 0.0597
380 B-CELL LYMPHOMA 174 0.0596
381 PLEURISY 310 0.0595
382 COELIAC DISEASE 452 0.0593
383 SKIN LACERATION 461 0.0593
384 SKIN ATROPHY 268 0.0590
385 LIVER FUNCTION TEST ABNORMAL 1540 0.0586
386 BEDRIDDEN 640 0.0586
387 PHYSICAL DISABILITY 231 0.0585
388 LYMPHADENOPATHY 1679 0.0582
389 LUNG INFECTION 905 0.0580
390 PULMONARY TUBERCULOSIS 210 0.0580
391 ACCIDENT 541 0.0578
392 HEPATIC FIBROSIS 156 0.0578
393 SKIN REACTION 647 0.0577
394 SCAB 519 0.0576
395 CELLULITIS 2418 0.0571
396 VIRAL INFECTION 1455 0.0571
397 PRODUCT STORAGE ERROR 2708 0.0571
398 MELANOCYTIC NAEVUS 202 0.0570
399 SQUAMOUS CELL CARCINOMA 436 0.0568
400 ABSCESS LIMB 190 0.0566
401 DENTAL CARIES 524 0.0563
402 CHRONIC SINUSITIS 159 0.0561
403 GASTROINTESTINAL INFECTION 392 0.0560
404 GROIN PAIN 415 0.0559
405 FOOT FRACTURE 889 0.0557
406 BONE DISORDER 906 0.0557
407 EPIGASTRIC DISCOMFORT 182 0.0556
408 BRONCHIECTASIS 274 0.0555
409 TONGUE DISORDER 357 0.0554
410 VARICOSE VEIN 237 0.0549
411 TOOTH EXTRACTION 577 0.0549
412 TYPE 2 DIABETES MELLITUS 1491 0.0548
413 LIMB INJURY 1154 0.0548
414 COUGH 11998 0.0548
415 TENDONITIS 723 0.0545
416 MOUTH ULCERATION 900 0.0544
417 SKIN WARM 258 0.0544
418 IMPAIRED WORK ABILITY 1008 0.0543
419 GAIT DISTURBANCE 8664 0.0543
420 BODY TEMPERATURE INCREASED 943 0.0542
421 ADVERSE DRUG REACTION 3559 0.0541
422 LUNG DISORDER 2071 0.0540
423 CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR 1177 0.0539
424 HEPATIC STEATOSIS 805 0.0539
425 EAR DISORDER 205 0.0538
426 LUNG NEOPLASM 207 0.0537
427 BACK PAIN 10295 0.0536
428 DEVICE FAILURE 629 0.0536
429 POSTOPERATIVE WOUND INFECTION 286 0.0535
430 OSTEOPOROSIS 1848 0.0535
431 INTENTIONAL PRODUCT MISUSE 3746 0.0533
432 BREAST MASS 292 0.0527
433 EYE DISORDER 1375 0.0525
434 PULMONARY CONGESTION 554 0.0525
435 SKIN LESION 1129 0.0524
436 HEPATIC CIRRHOSIS 753 0.0523
437 NEPHROLITHIASIS 1869 0.0523
438 MULTIPLE ALLERGIES 313 0.0522
439 NAIL DISCOLOURATION 167 0.0522
440 FUNGAL INFECTION 1404 0.0522
441 DEVICE DIFFICULT TO USE 1767 0.0517
442 HERPES VIRUS INFECTION 242 0.0516
443 RESPIRATORY DISORDER 1251 0.0513
444 NERVE INJURY 484 0.0513
445 MUSCLE SPASTICITY 557 0.0510
446 RASH PAPULAR 983 0.0510
447 RASH 17212 0.0510
448 STRESS 2890 0.0507
449 HYSTERECTOMY 340 0.0506
450 BACK DISORDER 678 0.0505
451 LIVER DISORDER 1776 0.0504
452 RHINITIS 324 0.0502
453 UNDERDOSE 2932 0.0500
454 THERAPY CESSATION 1953 0.0497
455 SKIN FISSURES 573 0.0495
456 GLAUCOMA 784 0.0494
457 PURULENT DISCHARGE 180 0.0493
458 GASTROINTESTINAL TOXICITY 161 0.0493
459 UPPER LIMB FRACTURE 850 0.0491
460 SKIN DISCOLOURATION 1862 0.0491
461 SEASONAL ALLERGY 494 0.0491
462 ERYSIPELAS 202 0.0488
463 CATARACT 2226 0.0488
464 LIGAMENT SPRAIN 378 0.0487
465 SUBCUTANEOUS ABSCESS 194 0.0484
466 BACK INJURY 386 0.0483
467 SPINAL OSTEOARTHRITIS 358 0.0480
468 BLOOD TEST ABNORMAL 514 0.0475
469 VASCULITIS 443 0.0475
470 ANKLE FRACTURE 611 0.0475
471 VAGINAL INFECTION 181 0.0468
472 DRY EYE 1497 0.0467
473 ADVERSE EVENT 3505 0.0466
474 FOOD ALLERGY 222 0.0465
475 HAND FRACTURE 269 0.0464
476 ABASIA 1147 0.0464
477 OEDEMA PERIPHERAL 4928 0.0463
478 SKIN DISORDER 1207 0.0461
479 HYPOAESTHESIA 5696 0.0460
480 ONYCHOCLASIS 251 0.0460
481 EYE INFLAMMATION 310 0.0459
482 OSTEOMYELITIS 715 0.0457
483 URTICARIA 5879 0.0452
484 GINGIVITIS 207 0.0452
485 TIBIA FRACTURE 175 0.0451
486 MUSCULOSKELETAL CHEST PAIN 565 0.0448
487 URINARY TRACT INFECTION 6006 0.0448
488 MUSCLE STRAIN 320 0.0447
489 EAR DISCOMFORT 360 0.0446
490 MALAISE 16468 0.0446
491 SLEEP DISORDER 2357 0.0444
492 IMPAIRED GASTRIC EMPTYING 270 0.0442
493 ORAL DISORDER 266 0.0439
494 UMBILICAL HERNIA 168 0.0439
495 FATIGUE 27049 0.0437
496 INTERSTITIAL LUNG DISEASE 1633 0.0435
497 PELVIC FRACTURE 273 0.0434
498 HEPATOTOXICITY 748 0.0431
499 HEADACHE 22161 0.0431
500 FACIAL PAIN 306 0.0426
501 FOOD POISONING 166 0.0425
502 SQUAMOUS CELL CARCINOMA OF SKIN 194 0.0424
503 TENDON RUPTURE 448 0.0423
504 PULMONARY THROMBOSIS 364 0.0421
505 PNEUMONIA 10696 0.0420
506 RASH MACULAR 1131 0.0419
507 FEELING HOT 2146 0.0418
508 APHONIA 452 0.0416
509 GASTROINTESTINAL PAIN 352 0.0414
510 WRIST FRACTURE 409 0.0414
511 DERMATITIS CONTACT 366 0.0414
512 BACTERIAL INFECTION 587 0.0412
513 OSTEOPENIA 538 0.0411
514 PHOTOSENSITIVITY REACTION 557 0.0411
515 THROAT IRRITATION 1445 0.0410
516 ROAD TRAFFIC ACCIDENT 1389 0.0408
517 DIABETES MELLITUS 2653 0.0406
518 BLEPHAROSPASM 159 0.0405
519 THERMAL BURN 244 0.0404
520 CHOLECYSTECTOMY 368 0.0403
521 SCOLIOSIS 211 0.0403
522 THYROID DISORDER 497 0.0402
523 ERYTHEMA 6726 0.0401
524 ACTIVITIES OF DAILY LIVING IMPAIRED 791 0.0399
525 GUILLAIN-BARRE SYNDROME 149 0.0398
526 OPTIC NEURITIS 308 0.0397
527 HEARING IMPAIRED 238 0.0396
528 SKIN SWELLING 220 0.0396
529 SUNBURN 253 0.0395
530 PAIN IN JAW 954 0.0394
531 PYREXIA 11111 0.0393
532 SENSATION OF HEAVINESS 152 0.0391
533 OCCUPATIONAL EXPOSURE TO PRODUCT 190 0.0390
534 CARDIAC OPERATION 253 0.0387
535 STAPHYLOCOCCAL SEPSIS 166 0.0386
536 VEIN DISORDER 165 0.0385
537 HYPERAESTHESIA 277 0.0385
538 HYPOACUSIS 1264 0.0384
539 RASH GENERALISED 996 0.0384
540 GASTRIC DISORDER 1318 0.0382
541 MENINGITIS 205 0.0381
542 PRURITUS 10412 0.0381
543 HERNIA 576 0.0381
544 PHOTOPHOBIA 550 0.0381
545 HEAD DISCOMFORT 513 0.0378
546 INFLUENZA LIKE ILLNESS 2687 0.0378
547 COLON CANCER 464 0.0377
548 HEPATITIS 781 0.0376
549 BLOOD DISORDER 248 0.0375
550 TERMINAL STATE 208 0.0374
551 SCAR 538 0.0374
552 SPINAL FRACTURE 582 0.0371
553 DYSSTASIA 911 0.0371
554 PRODUCT USE ISSUE 5279 0.0368
555 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 405 0.0368
556 LABORATORY TEST ABNORMAL 873 0.0368
557 PREGNANCY 667 0.0366
558 ORAL CANDIDIASIS 364 0.0364
559 FEMUR FRACTURE 982 0.0363
560 VITAMIN D DEFICIENCY 285 0.0362
561 PRESCRIBED OVERDOSE 558 0.0361
562 DEAFNESS 750 0.0360
563 STRESS FRACTURE 171 0.0356
564 OVERWEIGHT 153 0.0354
565 DRUG SPECIFIC ANTIBODY PRESENT 171 0.0353
566 DIFFUSE LARGE B-CELL LYMPHOMA 183 0.0353
567 GINGIVAL PAIN 229 0.0351
568 FEELING OF BODY TEMPERATURE CHANGE 171 0.0350
569 GENERAL PHYSICAL HEALTH DETERIORATION 2969 0.0350
570 NEOPLASM MALIGNANT 1827 0.0349
571 GENERALISED OEDEMA 339 0.0348
572 INSURANCE ISSUE 212 0.0347
573 INGUINAL HERNIA 176 0.0347
574 HYPOKINESIA 425 0.0346
575 EMPHYSEMA 299 0.0346
576 MIGRAINE 2566 0.0346
577 SKIN CANCER 598 0.0346
578 INTENTIONAL DOSE OMISSION 403 0.0344
579 ENCEPHALITIS 182 0.0344
580 GENERAL SYMPTOM 226 0.0343
581 NASAL DRYNESS 173 0.0343
582 WHITE BLOOD CELL COUNT ABNORMAL 173 0.0343
583 SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION 244 0.0339
584 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 2412 0.0338
585 GENERALISED ERYTHEMA 193 0.0338
586 BLOOD PRESSURE ABNORMAL 509 0.0338
587 DYSPHONIA 1584 0.0338
588 UTERINE LEIOMYOMA 206 0.0338
589 BLOOD IRON DECREASED 294 0.0337
590 PHARYNGEAL OEDEMA 509 0.0336
591 BURNING SENSATION 1959 0.0334
592 PARAESTHESIA 4442 0.0333
593 ABSCESS 428 0.0332
594 VITAMIN D DECREASED 237 0.0330
595 PRESCRIBED UNDERDOSE 512 0.0329
596 FRUSTRATION TOLERANCE DECREASED 198 0.0328
597 DRY THROAT 269 0.0326
598 CONJUNCTIVITIS 430 0.0324
599 DIVERTICULUM 218 0.0323
600 WEIGHT INCREASED 5760 0.0322
601 LYMPHOEDEMA 174 0.0321
602 POST PROCEDURAL COMPLICATION 517 0.0320
603 CANDIDA INFECTION 399 0.0319
604 STENT PLACEMENT 219 0.0318
605 HYPERTENSION 5452 0.0318
606 ORAL PAIN 597 0.0318
607 GALLBLADDER DISORDER 488 0.0316
608 TEMPERATURE INTOLERANCE 249 0.0316
609 BRAIN NEOPLASM 229 0.0315
610 HIP FRACTURE 811 0.0314
611 OFF LABEL USE 18374 0.0314
612 INTENTIONAL PRODUCT USE ISSUE 2057 0.0314
613 SPINAL COMPRESSION FRACTURE 234 0.0311
614 NASAL DISCOMFORT 207 0.0309
615 MUSCULAR WEAKNESS 2863 0.0308
616 LACRIMATION INCREASED 680 0.0306
617 CONCUSSION 188 0.0306
618 URINE ODOUR ABNORMAL 152 0.0305
619 WRONG TECHNIQUE IN DRUG USAGE PROCESS 1107 0.0304
620 PYELONEPHRITIS 209 0.0304
621 HEPATITIS C 341 0.0302
622 NEEDLE ISSUE 559 0.0301
623 MOTOR DYSFUNCTION 247 0.0301
624 WHEEZING 1324 0.0301
625 EYE DISCHARGE 224 0.0301
626 FALL 8147 0.0300
627 FEELING ABNORMAL 6209 0.0300
628 CHILLS 2886 0.0298
629 VISUAL IMPAIRMENT 2817 0.0297
630 NEURALGIA 567 0.0296
631 MEMORY IMPAIRMENT 3361 0.0296
632 FRACTURE 466 0.0296
633 ABDOMINAL PAIN UPPER 4834 0.0294
634 FEEDING DISORDER 397 0.0292
635 CORONARY ARTERY BYPASS 149 0.0290
636 ESCHERICHIA INFECTION 181 0.0289
637 DEVICE DEFECTIVE 168 0.0287
638 RIB FRACTURE 481 0.0287
639 ANAPHYLACTIC REACTION 1186 0.0286
640 ORAL DISCOMFORT 329 0.0285
641 ULCER HAEMORRHAGE 158 0.0285
642 DRY MOUTH 1832 0.0284
643 TENDON PAIN 180 0.0284
644 NEOPLASM 257 0.0283
645 DERMATITIS 425 0.0280
646 EYE PAIN 1128 0.0280
647 IRON DEFICIENCY ANAEMIA 206 0.0278
648 ALANINE AMINOTRANSFERASE INCREASED 1426 0.0276
649 NERVOUSNESS 1277 0.0276
650 MENSTRUAL DISORDER 189 0.0275
651 SKIN EXFOLIATION 1733 0.0275
652 ILLNESS 1338 0.0272
653 RENAL CYST 184 0.0271
654 SENSORY LOSS 183 0.0271
655 FLANK PAIN 209 0.0271
656 NAUSEA 17107 0.0267
657 GASTRIC ULCER 431 0.0267
658 MUSCLE TIGHTNESS 362 0.0267
659 GINGIVAL BLEEDING 277 0.0265
660 DEVICE MALFUNCTION 1267 0.0265
661 ASPARTATE AMINOTRANSFERASE INCREASED 1174 0.0263
662 SWELLING FACE 1400 0.0263
663 BONE PAIN 1268 0.0262
664 OVARIAN CANCER 209 0.0261
665 DRUG-INDUCED LIVER INJURY 529 0.0260
666 WHITE BLOOD CELL COUNT INCREASED 844 0.0259
667 ASTHMA 2069 0.0258
668 LEUKAEMIA 199 0.0258
669 MACULAR DEGENERATION 243 0.0258
670 SLUGGISHNESS 216 0.0256
671 THYROID CANCER 277 0.0255
672 HIATUS HERNIA 283 0.0254
673 EYE PRURITUS 575 0.0254
674 INFARCTION 159 0.0254
675 EYE SWELLING 750 0.0253
676 EXPOSURE DURING PREGNANCY 1217 0.0253
677 FEELING COLD 584 0.0252
678 LUNG NEOPLASM MALIGNANT 916 0.0252
679 MUSCLE SPASMS 3802 0.0251
680 FACIAL PARALYSIS 162 0.0250
681 EXTRA DOSE ADMINISTERED 580 0.0248
682 MUSCLE DISORDER 175 0.0247
683 OEDEMA 1060 0.0246
684 APPENDICITIS 176 0.0245
685 CHOLELITHIASIS 668 0.0245
686 OCULAR HYPERAEMIA 840 0.0245
687 SEPTIC SHOCK 822 0.0245
688 INSOMNIA 5421 0.0244
689 OCULAR DISCOMFORT 170 0.0241
690 SEPSIS 2192 0.0240
691 GOUT 349 0.0240
692 ASTHENIA 7326 0.0240
693 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 1031 0.0239
694 CHEST PAIN 3722 0.0238
695 BLOOD URINE PRESENT 382 0.0237
696 LEUKOPENIA 946 0.0237
697 SLEEP APNOEA SYNDROME 386 0.0236
698 UTERINE CANCER 176 0.0235
699 PLATELET COUNT INCREASED 248 0.0235
700 BREAST CANCER 2031 0.0233
701 DYSPEPSIA 1826 0.0233
702 VISUAL ACUITY REDUCED 718 0.0232
703 AORTIC ANEURYSM 153 0.0231
704 ECZEMA 555 0.0230
705 WHITE BLOOD CELL COUNT DECREASED 2016 0.0230
706 VOMITING 8646 0.0230
707 CAESAREAN SECTION 240 0.0230
708 DIARRHOEA 11514 0.0228
709 PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY 154 0.0227
710 EYE HAEMORRHAGE 255 0.0225
711 PNEUMOCYSTIS JIROVECII PNEUMONIA 162 0.0225
712 RENAL DISORDER 857 0.0224
713 BREAST PAIN 205 0.0222
714 UROSEPSIS 164 0.0221
715 BLADDER DISORDER 186 0.0221
716 THERAPEUTIC RESPONSE SHORTENED 352 0.0221
717 POOR QUALITY SLEEP 368 0.0220
718 COLITIS 614 0.0220
719 RED BLOOD CELL COUNT DECREASED 512 0.0220
720 CROHN'S DISEASE 151 0.0220
721 HYPERHIDROSIS 2385 0.0219
722 ABORTION SPONTANEOUS 742 0.0218
723 PRODUCT DOSE OMISSION 1444 0.0217
724 INJURY 1355 0.0217
725 PAIN OF SKIN 491 0.0216
726 CONFUSIONAL STATE 2892 0.0215
727 DEVICE RELATED INFECTION 286 0.0215
728 DEVICE USE ERROR 526 0.0215
729 BLINDNESS 690 0.0214
730 DIZZINESS 8725 0.0214
731 EPISTAXIS 1328 0.0214
732 PNEUMONITIS 430 0.0214
733 RETINAL DETACHMENT 157 0.0213
734 PERIPHERAL COLDNESS 243 0.0213
735 DYSPNOEA 9774 0.0212
736 ATELECTASIS 175 0.0211
737 CHEST DISCOMFORT 1711 0.0211
738 CRYING 670 0.0210
739 PRODUCT DISPENSING ERROR 294 0.0210
740 AMNESIA 1170 0.0210
741 WEIGHT DECREASED 4737 0.0209
742 CORONARY ARTERY OCCLUSION 254 0.0208
743 THROMBOSIS 1400 0.0208
744 MUSCLE ATROPHY 197 0.0208
745 HYPOTHYROIDISM 510 0.0207
746 DYSURIA 632 0.0205
747 MYALGIA 2830 0.0203
748 VERTIGO 1032 0.0203
749 DEPRESSION 3937 0.0201
750 DEPRESSED MOOD 836 0.0200
751 CARDIAC MURMUR 154 0.0200
752 DIPLOPIA 415 0.0199
753 INFLAMMATORY BOWEL DISEASE 166 0.0199
754 ACNE 1295 0.0196
755 GASTROENTERITIS 233 0.0196
756 HOT FLUSH 1102 0.0194
757 BONE DENSITY DECREASED 551 0.0194
758 INTESTINAL PERFORATION 175 0.0193
759 CLOSTRIDIUM DIFFICILE INFECTION 319 0.0192
760 QUALITY OF LIFE DECREASED 211 0.0192
761 NEUROPATHY PERIPHERAL 1383 0.0192
762 FEAR 463 0.0190
763 GASTRITIS 414 0.0189
764 MULTIPLE FRACTURES 280 0.0189
765 HEAD INJURY 479 0.0189
766 GASTROOESOPHAGEAL REFLUX DISEASE 1206 0.0188
767 BLOOD PRESSURE INCREASED 2363 0.0188
768 MUSCLE TWITCHING 365 0.0188
769 DISEASE RECURRENCE 623 0.0187
770 PNEUMOTHORAX 236 0.0187
771 MOVEMENT DISORDER 501 0.0186
772 BLOOD PRESSURE FLUCTUATION 380 0.0185
773 MICTURITION URGENCY 168 0.0184
774 EYELID OEDEMA 194 0.0183
775 EATING DISORDER 325 0.0183
776 TINNITUS 689 0.0183
777 TRANSAMINASES INCREASED 337 0.0183
778 LIP SWELLING 496 0.0181
779 NERVOUS SYSTEM DISORDER 497 0.0181
780 HYPOPHAGIA 361 0.0181
781 ABDOMINAL PAIN 3407 0.0181
782 VISION BLURRED 1981 0.0180
783 COLD SWEAT 265 0.0180
784 SPLENOMEGALY 175 0.0179
785 DECREASED APPETITE 3240 0.0179
786 FEELING JITTERY 294 0.0178
787 HUNGER 153 0.0177
788 HAEMORRHOIDS 288 0.0177
789 POLYNEUROPATHY 160 0.0177
790 PALLOR 409 0.0177
791 BODY TEMPERATURE DECREASED 151 0.0177
792 BLOOD GLUCOSE ABNORMAL 268 0.0176
793 SWOLLEN TONGUE 461 0.0174
794 HYPERSOMNIA 403 0.0174
795 HOSPITALISATION 1914 0.0174
796 PETECHIAE 149 0.0173
797 DRY SKIN 1683 0.0173
798 POLLAKIURIA 587 0.0173
799 CHOLECYSTITIS 166 0.0172
800 CARDIAC DISORDER 1356 0.0171
801 BLOOD PRESSURE SYSTOLIC INCREASED 269 0.0171
802 THROAT TIGHTNESS 379 0.0170
803 BLINDNESS UNILATERAL 195 0.0170
804 DRUG RESISTANCE 335 0.0169
805 MENORRHAGIA 331 0.0168
806 MULTIPLE SCLEROSIS 680 0.0168
807 HYPOAESTHESIA ORAL 209 0.0167
808 TOOTH LOSS 300 0.0167
809 PARALYSIS 200 0.0167
810 PROCEDURAL PAIN 357 0.0166
811 BLOOD COUNT ABNORMAL 255 0.0165
812 PLEURAL EFFUSION 827 0.0163
813 ABDOMINAL DISTENSION 1337 0.0162
814 HAEMATOCRIT DECREASED 282 0.0162
815 PRESYNCOPE 313 0.0161
816 RENAL IMPAIRMENT 1064 0.0161
817 DEMENTIA 336 0.0160
818 RESTLESS LEGS SYNDROME 244 0.0160
819 MYOCARDIAL INFARCTION 2526 0.0159
820 LOSS OF CONSCIOUSNESS 1685 0.0158
821 MOOD ALTERED 349 0.0157
822 LETHARGY 756 0.0157
823 DRUG ADMINISTERED AT INAPPROPRIATE SITE 165 0.0156
824 SENSORY DISTURBANCE 221 0.0156
825 FLUID RETENTION 660 0.0156
826 HEPATIC FUNCTION ABNORMAL 447 0.0156
827 TRANSIENT ISCHAEMIC ATTACK 454 0.0156
828 BLOOD CREATININE INCREASED 854 0.0155
829 PERICARDIAL EFFUSION 282 0.0154
830 BALANCE DISORDER 1111 0.0153
831 BREAST CANCER FEMALE 374 0.0152
832 RASH MACULO-PAPULAR 264 0.0152
833 HYPERLIPIDAEMIA 158 0.0152
834 PULMONARY EMBOLISM 1248 0.0152
835 ANGINA PECTORIS 381 0.0151
836 COVID-19 1838 0.0149
837 PARAESTHESIA ORAL 170 0.0149
838 BLOOD POTASSIUM INCREASED 199 0.0147
839 ANXIETY 3505 0.0146
840 INTRAOCULAR PRESSURE INCREASED 158 0.0146
841 PALPITATIONS 1398 0.0145
842 DEEP VEIN THROMBOSIS 840 0.0145
843 CEREBROVASCULAR ACCIDENT 2115 0.0145
844 DYSPNOEA EXERTIONAL 412 0.0142
845 PANCREATITIS 621 0.0142
846 BLOOD POTASSIUM DECREASED 351 0.0141
847 INCREASED APPETITE 189 0.0140
848 CARDIOMEGALY 156 0.0140
849 COORDINATION ABNORMAL 174 0.0140
850 ATRIAL FIBRILLATION 1112 0.0139
851 CARDIOMYOPATHY 173 0.0139
852 MOOD SWINGS 382 0.0138
853 BRONCHOSPASM 166 0.0138
854 HAEMATOMA 307 0.0137
855 DELIRIUM 369 0.0136
856 ANAPHYLACTIC SHOCK 266 0.0135
857 EMOTIONAL DISORDER 353 0.0135
858 SYNCOPE 1116 0.0134
859 PROTEINURIA 191 0.0134
860 PRODUCT DOSE OMISSION ISSUE 1881 0.0133
861 EYE IRRITATION 520 0.0132
862 DRUG DISPENSING ERROR 202 0.0132
863 CARDIAC FAILURE CONGESTIVE 978 0.0131
864 HAEMOGLOBIN DECREASED 1121 0.0131
865 HAEMATOCHEZIA 558 0.0130
866 THERAPEUTIC RESPONSE UNEXPECTED 495 0.0130
867 PANIC ATTACK 390 0.0129
868 RENAL FAILURE 1521 0.0129
869 BLOOD TRIGLYCERIDES INCREASED 194 0.0129
870 HAEMOPTYSIS 300 0.0128
871 COLITIS ULCERATIVE 386 0.0128
872 TREMOR 1781 0.0127
873 ANAEMIA 2014 0.0127
874 PREMATURE BABY 324 0.0127
875 DYSPHAGIA 949 0.0127
876 MULTI-ORGAN FAILURE 219 0.0126
877 FAECES DISCOLOURED 228 0.0126
878 RECTAL HAEMORRHAGE 455 0.0126
879 HEART RATE IRREGULAR 249 0.0125
880 PLATELET COUNT DECREASED 1073 0.0125
881 RETCHING 209 0.0122
882 DEVICE LEAKAGE 278 0.0121
883 HAEMORRHAGE 1010 0.0121
884 INCORRECT DOSE ADMINISTERED 1838 0.0121
885 METASTASES TO LIVER 166 0.0120
886 ABDOMINAL PAIN LOWER 255 0.0120
887 DYSGEUSIA 772 0.0120
888 THIRST 173 0.0119
889 CARDIAC FAILURE 783 0.0119
890 URINARY INCONTINENCE 292 0.0119
891 SPEECH DISORDER 521 0.0119
892 SOMNOLENCE 1937 0.0118
893 MEDICATION ERROR 535 0.0117
894 CYTOMEGALOVIRUS INFECTION 154 0.0117
895 PRODUCT USE IN UNAPPROVED INDICATION 1886 0.0116
896 CHOKING 177 0.0115
897 HEART RATE INCREASED 930 0.0115
898 PREMATURE DELIVERY 153 0.0115
899 MENTAL DISORDER 409 0.0114
900 PULMONARY OEDEMA 419 0.0113
901 DRUG ADMINISTRATION ERROR 341 0.0111
902 ARRHYTHMIA 449 0.0111
903 THINKING ABNORMAL 181 0.0111
904 PELVIC PAIN 166 0.0110
905 INCORRECT ROUTE OF DRUG ADMINISTRATION 394 0.0110
906 INTESTINAL OBSTRUCTION 314 0.0110
907 HAEMATURIA 321 0.0109
908 MUCOSAL INFLAMMATION 226 0.0108
909 COGNITIVE DISORDER 402 0.0106
910 DEHYDRATION 1175 0.0106
911 ACUTE RESPIRATORY DISTRESS SYNDROME 150 0.0104
912 BLOOD SODIUM DECREASED 159 0.0103
913 FLATULENCE 465 0.0103
914 PULMONARY HYPERTENSION 178 0.0100
915 PROSTATE CANCER 767 0.0100
916 PRODUCT PRESCRIBING ERROR 161 0.0100
917 TREATMENT NONCOMPLIANCE 397 0.0099
918 WRONG TECHNIQUE IN DEVICE USAGE PROCESS 282 0.0098
919 RESPIRATORY FAILURE 589 0.0097
920 MENTAL IMPAIRMENT 195 0.0097
921 BLOOD ALKALINE PHOSPHATASE INCREASED 209 0.0096
922 SKIN IRRITATION 376 0.0096
923 HAEMATEMESIS 206 0.0096
924 HEART RATE DECREASED 282 0.0096
925 CHROMATURIA 182 0.0096
926 CARDIOVASCULAR DISORDER 221 0.0095
927 ASCITES 231 0.0095
928 COMA 376 0.0095
929 GLYCOSYLATED HAEMOGLOBIN INCREASED 182 0.0092
930 PANCYTOPENIA 404 0.0091
931 CORONARY ARTERY DISEASE 256 0.0091
932 PERITONITIS 160 0.0091
933 DISTURBANCE IN ATTENTION 413 0.0090
934 VAGINAL HAEMORRHAGE 336 0.0090
935 CONSTIPATION 1474 0.0089
936 ANGIOEDEMA 316 0.0088
937 BLOOD GLUCOSE DECREASED 365 0.0088
938 NEUTROPENIA 897 0.0087
939 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 923 0.0087
940 IRRITABILITY 447 0.0087
941 CONVULSION 490 0.0086
942 TACHYCARDIA 619 0.0085
943 APHASIA 215 0.0085
944 OXYGEN SATURATION DECREASED 356 0.0085
945 FREQUENT BOWEL MOVEMENTS 164 0.0085
946 FLUSHING 748 0.0084
947 OSTEONECROSIS 250 0.0084
948 EPILEPSY 198 0.0084
949 THROMBOCYTOPENIA 738 0.0083
950 ANGER 243 0.0083
951 HEPATIC FAILURE 209 0.0082
952 GAMMA-GLUTAMYLTRANSFERASE INCREASED 155 0.0080
953 DEATH 5518 0.0080
954 ACUTE MYOCARDIAL INFARCTION 201 0.0078
955 CEREBRAL INFARCTION 161 0.0078
956 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 313 0.0078
957 BLOOD GLUCOSE INCREASED 1231 0.0076
958 DISORIENTATION 257 0.0075
959 PANCREATIC CARCINOMA 196 0.0075
960 BLOOD PRESSURE DECREASED 398 0.0073
961 FOETAL EXPOSURE DURING PREGNANCY 452 0.0071
962 GASTRIC CANCER 168 0.0069
963 HYPOTENSION 1127 0.0069
964 JAUNDICE 160 0.0068
965 DISEASE PROGRESSION 611 0.0068
966 SKIN BURNING SENSATION 401 0.0067
967 DYSARTHRIA 211 0.0067
968 CEREBRAL HAEMORRHAGE 197 0.0066
969 DYSKINESIA 219 0.0065
970 BLADDER CANCER 370 0.0065
971 HYPOKALAEMIA 232 0.0063
972 SUICIDAL IDEATION 470 0.0062
973 DRUG EXPOSURE DURING PREGNANCY 205 0.0060
974 CARDIO-RESPIRATORY ARREST 220 0.0060
975 URINARY RETENTION 159 0.0059
976 RESTLESSNESS 182 0.0059
977 RENAL FAILURE ACUTE 246 0.0058
978 SEIZURE 492 0.0058
979 NEUTROPHIL COUNT DECREASED 172 0.0056
980 CARDIAC ARREST 368 0.0053
981 DRUG INTERACTION 686 0.0052
982 RENAL CANCER 240 0.0052
983 NIGHTMARE 150 0.0051
984 GASTROINTESTINAL HAEMORRHAGE 378 0.0051
985 OVERDOSE 788 0.0045
986 AGITATION 280 0.0044
987 HALLUCINATION 238 0.0041
988 ACUTE KIDNEY INJURY 441 0.0038
989 TOXICITY TO VARIOUS AGENTS 484 0.0037
990 NO ADVERSE EVENT 385 0.0032
991 CHRONIC KIDNEY DISEASE 209 0.0030
992 PRODUCT QUALITY ISSUE 340 0.0028
993 EMOTIONAL DISTRESS 310 0.0028
994 DRUG DEPENDENCE 396 0.0026