Drug Side Effects

ETANERCEPT

ETANERCEPT was reported 592886 times

ETANERCEPT is most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 INJECTION SITE RECALL REACTION 485 0.9642
1 HUMAN ANTICHIMERIC ANTIBODY POSITIVE 307 0.9192
2 ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE 5424 0.7950
3 RED BLOOD CELL SEDIMENTATION RATE 217 0.7834
4 RED BLOOD CELL SEDIMENTATION RATE ABNORMAL 1742 0.7657
5 ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY 498 0.7615
6 RHEUMATOID FACTOR POSITIVE 4245 0.7594
7 SWOLLEN JOINT COUNT INCREASED 2090 0.7082
8 PEMPHIGUS 8286 0.6937
9 C-REACTIVE PROTEIN ABNORMAL 4246 0.6886
10 INJECTION SITE MACULE 469 0.6877
11 RHEUMATIC FEVER 2835 0.6845
12 HAND DEFORMITY 8428 0.6664
13 C-REACTIVE PROTEIN 572 0.6605
14 SYNOVITIS 11089 0.6328
15 DUODENAL ULCER PERFORATION 4420 0.6316
16 GRANULOMA SKIN 512 0.6290
17 DEEP VEIN THROMBOSIS POSTOPERATIVE 1161 0.6269
18 LUPUS VULGARIS 624 0.5794
19 FACET JOINT SYNDROME 1563 0.5333
20 JOINT DESTRUCTION 810 0.5294
21 SLEEP DISORDER DUE TO GENERAL MEDICAL CONDITION, INSOMNIA TYPE 3275 0.5281
22 INJECTION SITE WARMTH 10383 0.5179
23 JUVENILE ARTHRITIS 168 0.5122
24 BODY HEIGHT BELOW NORMAL 322 0.5016
25 BONE EROSION 1720 0.5007
26 ADJUSTMENT DISORDER WITH DEPRESSED MOOD 945 0.4997
27 HELICOBACTER INFECTION 4703 0.4812
28 DISLOCATION OF VERTEBRA 990 0.4776
29 MUSCLE INJURY 3732 0.4761
30 RHEUMATOID NODULE 1294 0.4733
31 X-RAY ABNORMAL 812 0.4729
32 CONTRAINDICATED PRODUCT ADMINISTERED 12791 0.4378
33 FOLLICULITIS 4301 0.4353
34 RHEUMATOID ARTHRITIS 46373 0.4225
35 INJECTION SITE HAEMATOMA 6061 0.4203
36 WRIST DEFORMITY 250 0.4132
37 BLOOD PARATHYROID HORMONE DECREASED 604 0.4120
38 SERONEGATIVE ARTHRITIS 423 0.3946
39 FINGER DEFORMITY 1866 0.3944
40 BLOOD IRON ABNORMAL 368 0.3882
41 JUVENILE IDIOPATHIC ARTHRITIS 897 0.3801
42 RETINITIS 565 0.3662
43 GLOSSODYNIA 7845 0.3622
44 PERICARDITIS 5696 0.3561
45 DRUG TOLERANCE DECREASED 964 0.3547
46 SUBCUTANEOUS DRUG ABSORPTION IMPAIRED 176 0.3478
47 INJECTION SITE PRURITUS 22094 0.3441
48 INJECTION SITE ERYTHEMA 41026 0.3436
49 GRIP STRENGTH DECREASED 2744 0.3243
50 ENTHESOPATHY 494 0.3222
51 INJECTION SITE SWELLING 23263 0.3194
52 PERIPHERAL VENOUS DISEASE 1197 0.3162
53 RED BLOOD CELL SEDIMENTATION RATE INCREASED 3412 0.3154
54 INJECTION SITE INDURATION 3974 0.3144
55 INJECTION SITE REACTION 20886 0.3144
56 RHEUMATOID LUNG 290 0.3062
57 ANTIBIOTIC THERAPY 278 0.3022
58 JOINT ARTHROPLASTY 512 0.2941
59 PSORIATIC ARTHROPATHY 10919 0.2820
60 PANNICULITIS 661 0.2816
61 BUNION 201 0.2796
62 ARTHRODESIS 273 0.2777
63 INJECTION SITE IRRITATION 3376 0.2768
64 JOINT RANGE OF MOTION DECREASED 3516 0.2725
65 TRANSPLANT DYSFUNCTION 456 0.2673
66 WOUND 7176 0.2668
67 ARTHROPATHY 14425 0.2656
68 TUBERCULIN TEST POSITIVE 660 0.2611
69 RHEUMATOID FACTOR INCREASED 286 0.2607
70 INJECTION SITE DISCOLOURATION 3001 0.2507
71 INJECTION SITE RASH 7098 0.2439
72 TENOSYNOVITIS 657 0.2432
73 FOOT DEFORMITY 2623 0.2424
74 DEAFNESS TRANSITORY 202 0.2411
75 JOINT WARMTH 284 0.2367
76 ONYCHOMYCOSIS 1004 0.2366
77 THERAPEUTIC PRODUCT EFFECT DECREASED 9789 0.2293
78 AMAUROSIS FUGAX 233 0.2245
79 INJECTION SITE URTICARIA 5201 0.2232
80 ONYCHOMADESIS 886 0.2232
81 DRUG EFFECT INCOMPLETE 8086 0.2223
82 DACTYLITIS 212 0.2213
83 BURSITIS 2580 0.2213
84 LIMB DEFORMITY 344 0.2212
85 SYSTEMIC LUPUS ERYTHEMATOSUS RASH 172 0.2202
86 PARANASAL SINUS HYPERSECRETION 827 0.2194
87 SHOULDER ARTHROPLASTY 557 0.2191
88 JOINT SWELLING 25549 0.2187
89 KNEE ARTHROPLASTY 4383 0.2181
90 FOETAL MALFORMATION 232 0.2164
91 BREAST CANCER STAGE III 1321 0.2137
92 IRRITABLE BOWEL SYNDROME 4414 0.2135
93 BONE CYST 195 0.2113
94 JOINT STIFFNESS 5268 0.2065
95 IMPAIRED HEALING 6581 0.2061
96 FIBROMYALGIA 4841 0.2056
97 HIP ARTHROPLASTY 3005 0.2053
98 PSORIASIS 25032 0.1971
99 ANKYLOSING SPONDYLITIS 2470 0.1962
100 PUSTULAR PSORIASIS 659 0.1961
101 PLEURAL FIBROSIS 198 0.1951
102 WRIST SURGERY 173 0.1946
103 INJECTION SITE PAIN 56703 0.1945
104 LOCAL SWELLING 3317 0.1899
105 LIP DRY 1625 0.1895
106 IRITIS 562 0.1889
107 JOINT EFFUSION 1276 0.1888
108 MYCOBACTERIUM TUBERCULOSIS COMPLEX TEST POSITIVE 433 0.1882
109 SKIN PLAQUE 1533 0.1871
110 PORPHYRIA ACUTE 238 0.1839
111 RUBBER SENSITIVITY 274 0.1838
112 DEMYELINATION 739 0.1834
113 OPEN WOUND 205 0.1829
114 WOUND INFECTION 1909 0.1828
115 INJECTION SITE BRUISING 13738 0.1814
116 INJECTION SITE DISCOMFORT 1775 0.1797
117 DRUG INTOLERANCE 16729 0.1795
118 CHONDROPATHY 479 0.1785
119 JOINT CREPITATION 354 0.1783
120 HYPERCHOLESTEROLAEMIA 1636 0.1773
121 ANTIBODY TEST POSITIVE 290 0.1761
122 INCORRECT PRODUCT STORAGE 2258 0.1716
123 MUSCULOSKELETAL STIFFNESS 14556 0.1707
124 INJECTION SITE INFLAMMATION 803 0.1683
125 INJECTION SITE HYPERSENSITIVITY 490 0.1683
126 FOOT OPERATION 796 0.1673
127 LOWER RESPIRATORY TRACT INFECTION 7282 0.1668
128 TREATMENT FAILURE 13128 0.1656
129 NODULE 2107 0.1656
130 SINUSITIS 16544 0.1654
131 NAIL DISORDER 1381 0.1648
132 MOBILITY DECREASED 11308 0.1629
133 FEAR OF INJECTION 1065 0.1610
134 POLYARTHRITIS 811 0.1597
135 MUSCULOSKELETAL PAIN 8172 0.1579
136 EXOSTOSIS 1399 0.1578
137 JOINT LOCK 431 0.1550
138 SCLERITIS 238 0.1533
139 WALKING AID USER 978 0.1521
140 AUTOIMMUNE DISORDER 1388 0.1520
141 RESPIRATORY TRACT CONGESTION 2337 0.1515
142 SACROILIITIS 277 0.1496
143 SPINAL FUSION SURGERY 576 0.1483
144 HEPATIC ENZYME INCREASED 9644 0.1463
145 SCIATICA 2232 0.1457
146 PULMONARY FIBROSIS 2688 0.1454
147 ALANINE AMINOTRANSFERASE ABNORMAL 292 0.1439
148 SWELLING 12935 0.1428
149 OSTEOARTHRITIS 5894 0.1427
150 BRONCHITIS CHRONIC 341 0.1423
151 DRUG EFFECT DECREASED 7673 0.1423
152 INJECTION SITE VESICLES 816 0.1417
153 SYNOVIAL CYST 634 0.1395
154 C-REACTIVE PROTEIN INCREASED 4880 0.1381
155 BLEPHAROSPASM 810 0.1373
156 LIVE BIRTH 1080 0.1346
157 SINUS HEADACHE 777 0.1332
158 FINE MOTOR SKILL DYSFUNCTION 368 0.1324
159 TEMPERATURE REGULATION DISORDER 278 0.1321
160 MUSCULOSKELETAL DISORDER 2443 0.1308
161 SINUS CONGESTION 1724 0.1308
162 ANKLE OPERATION 182 0.1294
163 INFLAMMATION 6206 0.1252
164 LATENT TUBERCULOSIS 252 0.1245
165 INJECTION SITE EXTRAVASATION 1528 0.1245
166 DECREASED IMMUNE RESPONSIVENESS 1172 0.1242
167 THERAPEUTIC RESPONSE DECREASED 7247 0.1240
168 ARTHROPOD BITE 886 0.1240
169 LUPUS-LIKE SYNDROME 1081 0.1236
170 OBESITY 1908 0.1232
171 LIVER INJURY 2843 0.1227
172 RHEUMATIC DISORDER 231 0.1215
173 VIRAL UPPER RESPIRATORY TRACT INFECTION 564 0.1204
174 SENSITIVITY TO WEATHER CHANGE 603 0.1196
175 ADVERSE REACTION 1544 0.1195
176 INJECTION SITE PARAESTHESIA 175 0.1195
177 JOINT DISLOCATION 1209 0.1184
178 ARTHRITIS INFECTIVE 532 0.1180
179 CONTRAST MEDIA ALLERGY 201 0.1173
180 COELIAC DISEASE 1103 0.1159
181 LARYNGITIS 1219 0.1158
182 IRIDOCYCLITIS 346 0.1158
183 NASOPHARYNGITIS 20724 0.1156
184 INJECTION SITE HAEMORRHAGE 8834 0.1152
185 TOOTH INFECTION 1477 0.1151
186 ARTHRITIS 8805 0.1149
187 APPARENT DEATH 411 0.1140
188 PHARYNGITIS STREPTOCOCCAL 1201 0.1139
189 UPPER RESPIRATORY TRACT CONGESTION 322 0.1131
190 ROTATOR CUFF REPAIR 188 0.1130
191 INCREASED TENDENCY TO BRUISE 1015 0.1126
192 INFUSION RELATED REACTION 7205 0.1126
193 ARTHRALGIA 45139 0.1126
194 SARCOIDOSIS 519 0.1120
195 SPONDYLITIS 395 0.1119
196 INCORRECT STORAGE OF DRUG 193 0.1116
197 INTERVERTEBRAL DISCITIS 204 0.1113
198 LACERATION 1046 0.1111
199 THERAPEUTIC RESPONSE DELAYED 300 0.1103
200 UPPER RESPIRATORY TRACT INFECTION 4939 0.1103
201 ANIMAL BITE 280 0.1098
202 EAR INFECTION 2817 0.1095
203 DISCOMFORT 6377 0.1091
204 SKIN NECROSIS 555 0.1090
205 TYPE 2 DIABETES MELLITUS 3569 0.1086
206 BLISTER 5860 0.1078
207 ARTHROPOD STING 170 0.1060
208 INDURATION 184 0.1059
209 GAIT INABILITY 3320 0.1043
210 EAR PAIN 1954 0.1032
211 LOCALISED INFECTION 2427 0.1032
212 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 4714 0.1029
213 PHARYNGOLARYNGEAL PAIN 547 0.1028
214 ENDODONTIC PROCEDURE 255 0.1027
215 LOWER LIMB FRACTURE 1882 0.1023
216 ANTINUCLEAR ANTIBODY POSITIVE 326 0.1023
217 LIVER FUNCTION TEST INCREASED 2082 0.1014
218 DRUG EFFECT DELAYED 460 0.1014
219 LIMB OPERATION 462 0.1012
220 WHEELCHAIR USER 437 0.1004
221 INJECTION SITE MASS 3559 0.0997
222 TENDERNESS 997 0.0977
223 THYROID NEOPLASM 268 0.0976
224 INFECTION SUSCEPTIBILITY INCREASED 208 0.0974
225 MATERNAL EXPOSURE TIMING UNSPECIFIED 349 0.0972
226 INFECTION 13519 0.0968
227 PERIPHERAL SWELLING 14229 0.0959
228 STOMATITIS 5637 0.0956
229 VULVOVAGINAL MYCOTIC INFECTION 367 0.0955
230 FURUNCLE 736 0.0954
231 BRONCHITIS 6850 0.0943
232 UVEITIS 1199 0.0916
233 THERAPY NON-RESPONDER 3873 0.0904
234 INTERCEPTED PRODUCT ADMINISTRATION ERROR 686 0.0904
235 BASAL CELL CARCINOMA 1372 0.0903
236 NO THERAPEUTIC RESPONSE 1102 0.0903
237 BLOOD CHOLESTEROL INCREASED 4069 0.0898
238 NECK SURGERY 197 0.0897
239 PHARYNGITIS 1089 0.0897
240 DRUG TOLERANCE 441 0.0893
241 TOOTH ABSCESS 888 0.0888
242 PAIN IN EXTREMITY 25530 0.0888
243 JOINT INJURY 1844 0.0887
244 MACULE 238 0.0880
245 NIGHT SWEATS 2741 0.0877
246 HERPES ZOSTER 4912 0.0877
247 PRODUCT LABEL CONFUSION 490 0.0873
248 EAR CONGESTION 228 0.0869
249 PNEUMONIA VIRAL 267 0.0869
250 KNEE OPERATION 808 0.0867
251 NECK MASS 237 0.0865
252 INFUSION SITE REACTION 237 0.0863
253 SKIN ULCER 2160 0.0861
254 BACK INJURY 898 0.0858
255 SHOULDER OPERATION 344 0.0853
256 ARTHRITIS BACTERIAL 336 0.0849
257 SPINAL COLUMN INJURY 184 0.0848
258 IMMUNOSUPPRESSION 704 0.0847
259 CONTUSION 7904 0.0847
260 TUBERCULOSIS 1057 0.0845
261 ILL-DEFINED DISORDER 4995 0.0845
262 INCREASED UPPER AIRWAY SECRETION 428 0.0845
263 IMMOBILE 352 0.0837
264 SPINAL COLUMN STENOSIS 393 0.0831
265 NECK PAIN 4523 0.0831
266 SKIN PAPILLOMA 323 0.0826
267 HIP SURGERY 421 0.0825
268 INFLAMMATORY MARKER INCREASED 387 0.0824
269 DISABILITY 1577 0.0824
270 DIVERTICULITIS 2185 0.0816
271 ABDOMINAL DISCOMFORT 12891 0.0797
272 PRESCRIBED OVERDOSE 1487 0.0789
273 DRUG HYPERSENSITIVITY 14909 0.0786
274 IMMUNODEFICIENCY 1111 0.0784
275 ORAL SURGERY 176 0.0784
276 LYME DISEASE 252 0.0781
277 DEFORMITY 727 0.0780
278 HYPERSENSITIVITY 14015 0.0779
279 INCORRECT DISPOSAL OF PRODUCT 236 0.0774
280 HEPATIC ENZYME ABNORMAL 374 0.0773
281 CREPITATIONS 223 0.0759
282 LYMPHOMA 1143 0.0757
283 POST PROCEDURAL INFECTION 594 0.0757
284 INGROWING NAIL 172 0.0752
285 ALOPECIA 14354 0.0749
286 CYST 897 0.0740
287 MENISCUS INJURY 441 0.0737
288 SPINAL DISORDER 681 0.0737
289 SPINAL PAIN 835 0.0735
290 IMMUNE SYSTEM DISORDER 930 0.0728
291 SKIN INJURY 231 0.0724
292 DRUG ERUPTION 1235 0.0724
293 PAIN 43197 0.0721
294 STREPTOCOCCAL INFECTION 384 0.0712
295 GASTROINTESTINAL DISORDER 6012 0.0711
296 EXCORIATION 180 0.0709
297 CONDITION AGGRAVATED 20647 0.0708
298 MATERNAL EXPOSURE DURING PREGNANCY 6004 0.0707
299 HEPATIC CIRRHOSIS 1271 0.0703
300 ULCER 1088 0.0701
301 PRURITUS GENERALISED 1517 0.0700
302 FOOD ALLERGY 505 0.0697
303 CARPAL TUNNEL SYNDROME 940 0.0688
304 INFLUENZA 7451 0.0687
305 EXPIRED DEVICE USED 217 0.0687
306 TONSILLITIS 347 0.0683
307 THERAPEUTIC PRODUCT EFFECT INCOMPLETE 4639 0.0677
308 LUNG DISORDER 3216 0.0677
309 ACCIDENTAL EXPOSURE TO PRODUCT 6365 0.0676
310 OROPHARYNGEAL PAIN 6073 0.0675
311 GALLBLADDER OPERATION 261 0.0675
312 DRUG DOSE OMISSION 11158 0.0674
313 STAPHYLOCOCCAL INFECTION 2155 0.0668
314 MONOCYTE COUNT INCREASED 235 0.0664
315 SINUS DISORDER 1270 0.0658
316 COLITIS MICROSCOPIC 298 0.0657
317 PLANTAR FASCIITIS 214 0.0656
318 SURGERY 3648 0.0656
319 TOOTH FRACTURE 706 0.0655
320 SPINAL OPERATION 755 0.0655
321 OVARIAN CYST 643 0.0653
322 CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR 2139 0.0653
323 RASH VESICULAR 304 0.0652
324 LIVER DISORDER 2763 0.0642
325 MUSCULOSKELETAL DISCOMFORT 1071 0.0641
326 INTERVERTEBRAL DISC DISORDER 268 0.0641
327 WEIGHT BEARING DIFFICULTY 168 0.0637
328 INJECTION SITE NODULE 678 0.0636
329 GASTROENTERITIS VIRAL 1113 0.0635
330 SKIN MASS 404 0.0633
331 URINARY TRACT DISORDER 277 0.0633
332 PULMONARY MASS 907 0.0629
333 ORAL INFECTION 237 0.0626
334 KIDNEY INFECTION 1190 0.0624
335 SECRETION DISCHARGE 738 0.0624
336 MASS 850 0.0623
337 RHINORRHOEA 3881 0.0622
338 INTERVERTEBRAL DISC DEGENERATION 564 0.0620
339 TOOTHACHE 1090 0.0619
340 ULCER HAEMORRHAGE 407 0.0616
341 MALIGNANT MELANOMA 805 0.0616
342 FUNGAL SKIN INFECTION 237 0.0613
343 CATARACT OPERATION 351 0.0613
344 ROTATOR CUFF SYNDROME 772 0.0613
345 PULMONARY PAIN 168 0.0611
346 EYE INJURY 178 0.0611
347 ROAD TRAFFIC ACCIDENT 2474 0.0608
348 RASH PRURITIC 3162 0.0607
349 PRESCRIBED UNDERDOSE 1165 0.0604
350 EYE INFECTION 657 0.0604
351 DEAFNESS NEUROSENSORY 191 0.0603
352 TENDON DISORDER 383 0.0602
353 INTERVERTEBRAL DISC PROTRUSION 1282 0.0599
354 SLEEP DISORDER 4026 0.0596
355 INJURY ASSOCIATED WITH DEVICE 1133 0.0591
356 INJECTION SITE INJURY 307 0.0589
357 OSTEOPOROSIS 2361 0.0589
358 DRUG INEFFECTIVE 75212 0.0588
359 INJECTION SITE INFECTION 187 0.0587
360 SKIN INFECTION 634 0.0586
361 B-CELL LYMPHOMA 194 0.0583
362 SNEEZING 1261 0.0582
363 RESPIRATORY TRACT INFECTION 1459 0.0581
364 SCRATCH 572 0.0579
365 LIGAMENT RUPTURE 250 0.0579
366 ADRENAL INSUFFICIENCY 667 0.0579
367 SKIN HAEMORRHAGE 793 0.0578
368 LUNG INFECTION 899 0.0578
369 TOOTH DISORDER 1258 0.0576
370 SPINAL STENOSIS 225 0.0576
371 CUTANEOUS VASCULITIS 195 0.0576
372 INJECTION SITE PAPULE 251 0.0574
373 CYSTITIS 1787 0.0572
374 THERAPY INTERRUPTED 3690 0.0572
375 NASAL CONGESTION 3229 0.0570
376 GRANULOMA 191 0.0567
377 UNEVALUABLE EVENT 4169 0.0565
378 MUSCLE SPASTICITY 688 0.0565
379 HYPERCALCAEMIA 676 0.0564
380 TRIGGER FINGER 222 0.0563
381 PLEURISY 328 0.0561
382 HYPERKERATOSIS 302 0.0561
383 RESPIRATORY DISORDER 1633 0.0560
384 RASH PUSTULAR 398 0.0556
385 EYE OPERATION 237 0.0550
386 LIVER FUNCTION TEST ABNORMAL 1572 0.0549
387 TRANSPLANT REJECTION 427 0.0546
388 PARANASAL SINUS DISCOMFORT 198 0.0545
389 BACK DISORDER 865 0.0544
390 FOETAL DEATH 275 0.0543
391 LIMB DISCOMFORT 1627 0.0541
392 PULMONARY TUBERCULOSIS 224 0.0539
393 BREAST CANCER STAGE II 443 0.0539
394 WHEEZING 3059 0.0535
395 UPPER-AIRWAY COUGH SYNDROME 422 0.0534
396 HYPOAESTHESIA 7741 0.0530
397 PHYSICAL DISABILITY 232 0.0530
398 RASH ERYTHEMATOUS 2367 0.0530
399 NERVE COMPRESSION 473 0.0529
400 SPUTUM DISCOLOURED 485 0.0528
401 GENERAL SYMPTOM 389 0.0527
402 HEPATITIS 1301 0.0522
403 ORAL HERPES 979 0.0520
404 DERMATITIS ALLERGIC 622 0.0519
405 GASTRIC INFECTION 193 0.0519
406 GAIT DISTURBANCE 9705 0.0519
407 BONE DISORDER 933 0.0518
408 CONGENITAL ANOMALY 395 0.0518
409 CELLULITIS 2544 0.0518
410 BODY TEMPERATURE INCREASED 1034 0.0517
411 PREGNANCY 1027 0.0517
412 SKIN REACTION 703 0.0516
413 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 10046 0.0513
414 DEVICE DIFFICULT TO USE 3293 0.0512
415 BEDRIDDEN 653 0.0511
416 DEVICE ISSUE 4244 0.0508
417 TONGUE DISORDER 361 0.0506
418 VARICOSE VEIN 256 0.0506
419 LYMPHADENOPATHY 1730 0.0503
420 DEVICE FAILURE 739 0.0503
421 FOOT FRACTURE 930 0.0502
422 PRODUCT STORAGE ERROR 4204 0.0502
423 LUNG NEOPLASM 211 0.0501
424 GROIN PAIN 429 0.0500
425 SKIN ATROPHY 278 0.0500
426 HEPATIC STEATOSIS 898 0.0499
427 PULMONARY TOXICITY 337 0.0496
428 INTENTIONAL PRODUCT MISUSE 4179 0.0495
429 TENDONITIS 752 0.0495
430 TOOTH EXTRACTION 601 0.0495
431 PRODUCTIVE COUGH 2252 0.0495
432 ACCIDENT 571 0.0494
433 MELANOCYTIC NAEVUS 211 0.0494
434 SQUAMOUS CELL CARCINOMA 452 0.0493
435 GASTROINTESTINAL INFECTION 427 0.0493
436 IMPAIRED WORK ABILITY 1029 0.0491
437 DENTAL CARIES 530 0.0490
438 BRONCHIECTASIS 313 0.0490
439 EAR DISORDER 220 0.0490
440 URTICARIA 7827 0.0487
441 RASH 20201 0.0482
442 INJURY 3333 0.0481
443 ABSCESS LIMB 200 0.0481
444 BACK PAIN 10854 0.0480
445 PAPULE 321 0.0480
446 EPIGASTRIC DISCOMFORT 183 0.0479
447 SCAB 525 0.0479
448 SKIN WARM 270 0.0478
449 OEDEMA PERIPHERAL 5647 0.0473
450 VIRAL INFECTION 1521 0.0473
451 CHRONIC SINUSITIS 172 0.0471
452 SPINAL OSTEOARTHRITIS 405 0.0471
453 POSTOPERATIVE WOUND INFECTION 308 0.0471
454 ADVERSE EVENT 4219 0.0470
455 GENERAL PHYSICAL HEALTH DETERIORATION 5208 0.0470
456 ADVERSE DRUG REACTION 4062 0.0470
457 BREAST MASS 307 0.0470
458 UNDERDOSE 3330 0.0469
459 INCORRECT DOSE ADMINISTERED BY DEVICE 1118 0.0466
460 MOUTH ULCERATION 948 0.0465
461 ABASIA 1147 0.0464
462 HYSTERECTOMY 386 0.0462
463 LIMB INJURY 1208 0.0460
464 MULTIPLE ALLERGIES 347 0.0457
465 SKIN LACERATION 474 0.0455
466 RASH PAPULAR 991 0.0453
467 NERVE INJURY 491 0.0451
468 SKIN LESION 1178 0.0448
469 EYE DISORDER 1422 0.0448
470 FUNGAL INFECTION 1442 0.0445
471 NAIL DISCOLOURATION 169 0.0445
472 UPPER LIMB FRACTURE 865 0.0444
473 ERYSIPELAS 218 0.0443
474 HERPES VIRUS INFECTION 247 0.0441
475 PULMONARY CONGESTION 568 0.0440
476 NEPHROLITHIASIS 1943 0.0439
477 MALAISE 18717 0.0437
478 GLAUCOMA 816 0.0435
479 INCORRECT ROUTE OF PRODUCT ADMINISTRATION 691 0.0433
480 PURULENT DISCHARGE 181 0.0433
481 ANKLE FRACTURE 649 0.0430
482 OSTEOMYELITIS 754 0.0427
483 STRESS 2967 0.0426
484 RHINITIS 333 0.0425
485 SKIN DISCOLOURATION 1895 0.0425
486 THERAPY CESSATION 2104 0.0424
487 OEDEMA 2231 0.0424
488 GINGIVITIS 221 0.0420
489 SUBCUTANEOUS ABSCESS 196 0.0418
490 DRUG-INDUCED LIVER INJURY 1231 0.0418
491 DRY MOUTH 3252 0.0415
492 LIGAMENT SPRAIN 396 0.0414
493 BLOOD TEST ABNORMAL 558 0.0409
494 GENERALISED OEDEMA 487 0.0408
495 HEADACHE 24802 0.0408
496 CATARACT 2340 0.0407
497 VAGINAL INFECTION 187 0.0407
498 VASCULITIS 459 0.0406
499 FATIGUE 30414 0.0404
500 HEAD DISCOMFORT 685 0.0403
501 HAND FRACTURE 278 0.0403
502 FEELING HOT 2397 0.0401
503 PNEUMONIA 12537 0.0400
504 SKIN DISORDER 1288 0.0400
505 MIGRAINE 3665 0.0400
506 GASTROINTESTINAL TOXICITY 179 0.0398
507 ACTIVITIES OF DAILY LIVING IMPAIRED 789 0.0398
508 HEARING IMPAIRED 238 0.0396
509 PYREXIA 13286 0.0394
510 TENDON RUPTURE 476 0.0393
511 ORAL DISORDER 281 0.0393
512 INTENTIONAL PRODUCT USE ISSUE 3350 0.0392
513 HYPERTENSION 8045 0.0390
514 URINARY TRACT INFECTION 6434 0.0390
515 DRUG DOSE OMISSION BY DEVICE 2844 0.0388
516 TIBIA FRACTURE 178 0.0388
517 MUSCLE STRAIN 324 0.0385
518 ONYCHOCLASIS 256 0.0385
519 RASH GENERALISED 995 0.0384
520 EXPOSURE DURING PREGNANCY 2318 0.0383
521 MUSCULOSKELETAL CHEST PAIN 575 0.0382
522 OSTEOPENIA 569 0.0382
523 PRODUCT USE ISSUE 6836 0.0379
524 SEASONAL ALLERGY 511 0.0379
525 UMBILICAL HERNIA 171 0.0375
526 PELVIC FRACTURE 283 0.0375
527 HEPATOTOXICITY 800 0.0374
528 BREATH SOUNDS ABNORMAL 179 0.0374
529 INTERSTITIAL LUNG DISEASE 1744 0.0372
530 DIABETES MELLITUS 2778 0.0372
531 WRIST FRACTURE 433 0.0372
532 PHOTOPHOBIA 672 0.0371
533 WEIGHT INCREASED 7940 0.0369
534 EAR DISCOMFORT 366 0.0368
535 SQUAMOUS CELL CARCINOMA OF SKIN 215 0.0368
536 OPTIC NEURITIS 327 0.0368
537 STAPHYLOCOCCAL SEPSIS 178 0.0367
538 MYOSITIS 318 0.0367
539 GASTRIC DISORDER 1259 0.0366
540 SCOLIOSIS 220 0.0365
541 PHOTOSENSITIVITY REACTION 580 0.0363
542 THERMAL BURN 251 0.0362
543 LABORATORY TEST ABNORMAL 1034 0.0361
544 FOOD POISONING 184 0.0360
545 PULMONARY THROMBOSIS 382 0.0359
546 ERYTHEMA 7102 0.0356
547 CHOLECYSTECTOMY 392 0.0356
548 HAEMORRHAGIC STROKE 273 0.0355
549 FACIAL PAIN 307 0.0355
550 PARAESTHESIA 5447 0.0355
551 GASTROINTESTINAL PAIN 376 0.0354
552 BACTERIAL INFECTION 635 0.0354
553 SUNBURN 256 0.0353
554 DYSSTASIA 1004 0.0352
555 EYE INFLAMMATION 319 0.0351
556 PAIN IN JAW 969 0.0350
557 HYPERAESTHESIA 282 0.0348
558 THYROID DISORDER 520 0.0348
559 PRURITUS 12460 0.0345
560 DRY EYE 1582 0.0345
561 MUSCULAR WEAKNESS 3804 0.0345
562 THROAT IRRITATION 1489 0.0344
563 BLOOD DISORDER 269 0.0344
564 RASH MACULAR 1158 0.0344
565 VEIN DISORDER 169 0.0343
566 INFLUENZA LIKE ILLNESS 2758 0.0342
567 VITAMIN D DEFICIENCY 322 0.0342
568 APHONIA 462 0.0341
569 FEMUR FRACTURE 1033 0.0341
570 DERMATITIS CONTACT 375 0.0340
571 STRESS FRACTURE 180 0.0339
572 GENERALISED ERYTHEMA 193 0.0339
573 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 2409 0.0338
574 MEMORY IMPAIRMENT 4524 0.0338
575 CARDIAC OPERATION 276 0.0337
576 TASTE DISORDER 639 0.0334
577 COLON CANCER 485 0.0334
578 HERNIA 622 0.0333
579 MENINGITIS 216 0.0333
580 NORMAL NEWBORN 176 0.0333
581 PHARYNGEAL OEDEMA 511 0.0332
582 ABDOMINAL PAIN UPPER 6578 0.0331
583 TERMINAL STATE 216 0.0330
584 DEAFNESS 836 0.0329
585 OCCUPATIONAL EXPOSURE TO PRODUCT 208 0.0329
586 SCAR 550 0.0329
587 SKIN FISSURES 580 0.0327
588 DRUG USE DISORDER 255 0.0326
589 OCULAR DISCOMFORT 333 0.0323
590 DIVERTICULUM 229 0.0322
591 DYSPEPSIA 3053 0.0322
592 EMPHYSEMA 317 0.0321
593 DELIRIUM 1064 0.0317
594 SLEEP DISORDER DUE TO A GENERAL MEDICAL CONDITION 472 0.0316
595 CONFUSIONAL STATE 4983 0.0316
596 NEOPLASM MALIGNANT 2048 0.0316
597 HYPOACUSIS 1302 0.0313
598 INGUINAL HERNIA 185 0.0312
599 SPINAL FRACTURE 600 0.0311
600 HYPOKINESIA 439 0.0311
601 ORAL CANDIDIASIS 384 0.0306
602 ASTHMA 3287 0.0304
603 WRONG TECHNIQUE IN DRUG USAGE PROCESS 1107 0.0304
604 EPILEPSY 898 0.0304
605 FEELING OF BODY TEMPERATURE CHANGE 174 0.0304
606 SKIN CANCER 635 0.0303
607 GINGIVAL PAIN 233 0.0301
608 UTERINE LEIOMYOMA 215 0.0300
609 VITAMIN D DECREASED 249 0.0299
610 GALLBLADDER DISORDER 521 0.0299
611 SPINAL COMPRESSION FRACTURE 246 0.0297
612 BURNING SENSATION 2020 0.0296
613 ABSCESS 458 0.0295
614 AMNESIA 1875 0.0294
615 DRUG SPECIFIC ANTIBODY PRESENT 185 0.0294
616 TEMPERATURE INTOLERANCE 289 0.0293
617 WHITE BLOOD CELL COUNT ABNORMAL 180 0.0292
618 STENT PLACEMENT 226 0.0290
619 ORAL PAIN 634 0.0290
620 NASAL DRYNESS 175 0.0288
621 HEPATITIS C 344 0.0286
622 VISUAL IMPAIRMENT 3387 0.0285
623 DYSPHONIA 1619 0.0285
624 WHITE BLOOD CELL COUNT INCREASED 1064 0.0283
625 FALL 9134 0.0283
626 POST PROCEDURAL COMPLICATION 531 0.0282
627 ENCEPHALITIS 188 0.0281
628 INSOMNIA 7303 0.0281
629 HIP FRACTURE 875 0.0281
630 BLOOD PRESSURE ABNORMAL 538 0.0281
631 NEEDLE ISSUE 766 0.0280
632 FRACTURE 512 0.0278
633 DRY THROAT 273 0.0277
634 SKIN SWELLING 223 0.0276
635 INTENTIONAL DOSE OMISSION 699 0.0275
636 MUSCLE SPASMS 4868 0.0273
637 LYMPHOEDEMA 182 0.0273
638 CHILLS 3107 0.0272
639 CHEST PAIN 4913 0.0272
640 FEELING ABNORMAL 6358 0.0271
641 PYELONEPHRITIS 225 0.0269
642 BRAIN NEOPLASM 239 0.0268
643 FRUSTRATION TOLERANCE DECREASED 207 0.0267
644 BLOOD IRON DECREASED 304 0.0267
645 OFF LABEL USE 22314 0.0267
646 NASAL DISCOMFORT 207 0.0266
647 CANDIDA INFECTION 421 0.0263
648 DIFFUSE LARGE B-CELL LYMPHOMA 191 0.0262
649 TENDON PAIN 192 0.0260
650 CONJUNCTIVITIS 460 0.0260
651 ALANINE AMINOTRANSFERASE INCREASED 1549 0.0259
652 CONCUSSION 194 0.0258
653 NEOPLASM 289 0.0258
654 ANAPHYLACTIC REACTION 1359 0.0256
655 RIB FRACTURE 508 0.0255
656 GASTROOESOPHAGEAL REFLUX DISEASE 1974 0.0255
657 HIATUS HERNIA 322 0.0254
658 IMPAIRED GASTRIC EMPTYING 291 0.0254
659 MOTOR DYSFUNCTION 249 0.0254
660 NERVOUSNESS 1299 0.0253
661 NAUSEA 19318 0.0253
662 NEURALGIA 592 0.0252
663 ESCHERICHIA INFECTION 199 0.0252
664 PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY 201 0.0251
665 THYROID CANCER 295 0.0250
666 LUNG NEOPLASM MALIGNANT 1005 0.0249
667 EYE PAIN 1323 0.0248
668 IRON DEFICIENCY ANAEMIA 220 0.0248
669 RENAL CYST 191 0.0247
670 ASPARTATE AMINOTRANSFERASE INCREASED 1269 0.0246
671 ASTHENIA 8953 0.0245
672 ORAL DISCOMFORT 331 0.0244
673 OVARIAN CANCER 221 0.0244
674 GASTRIC ULCER 453 0.0244
675 PRODUCT COMMUNICATION ISSUE 192 0.0242
676 FLANK PAIN 218 0.0240
677 MENSTRUAL DISORDER 191 0.0240
678 LACRIMATION INCREASED 690 0.0240
679 MUSCLE TIGHTNESS 376 0.0239
680 VOMITING 10820 0.0238
681 UTERINE CANCER 189 0.0237
682 SENSORY LOSS 186 0.0236
683 DERMATITIS 467 0.0235
684 BREAST CANCER 2165 0.0235
685 EYE DISCHARGE 229 0.0233
686 DEPRESSION 5175 0.0232
687 SWELLING FACE 1463 0.0232
688 BONE PAIN 1309 0.0231
689 SEPSIS 2491 0.0230
690 LEUKAEMIA 211 0.0229
691 SEPTIC SHOCK 947 0.0226
692 LEUKOPENIA 1093 0.0226
693 MACULAR DEGENERATION 259 0.0224
694 DEVICE USE ERROR 732 0.0224
695 BLINDNESS 878 0.0222
696 SKIN EXFOLIATION 1772 0.0222
697 SLUGGISHNESS 219 0.0222
698 MUSCLE DISORDER 176 0.0221
699 FEELING COLD 600 0.0221
700 FACIAL PARALYSIS 180 0.0221
701 DIARRHOEA 13714 0.0221
702 PRODUCT DOSE OMISSION 1441 0.0220
703 CAESAREAN SECTION 254 0.0220
704 FEEDING DISORDER 416 0.0220
705 VISUAL ACUITY REDUCED 721 0.0220
706 DIPLOPIA 552 0.0220
707 CHOLELITHIASIS 696 0.0219
708 DYSPNOEA 11961 0.0218
709 APPENDICITIS 195 0.0218
710 DIZZINESS 10505 0.0217
711 HYPERHIDROSIS 2727 0.0217
712 SLEEP APNOEA SYNDROME 405 0.0217
713 ILLNESS 2047 0.0216
714 DEVICE MALFUNCTION 1368 0.0216
715 DECREASED APPETITE 4828 0.0215
716 FLUID RETENTION 1060 0.0214
717 EYE SWELLING 766 0.0214
718 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 1078 0.0213
719 GINGIVAL BLEEDING 283 0.0213
720 PLATELET COUNT INCREASED 269 0.0212
721 BLOOD URINE PRESENT 394 0.0212
722 WEIGHT DECREASED 5707 0.0211
723 INFLAMMATORY BOWEL DISEASE 201 0.0209
724 GOUT 364 0.0209
725 UROSEPSIS 186 0.0209
726 BREAST PAIN 212 0.0204
727 WEIGHT FLUCTUATION 204 0.0203
728 RED BLOOD CELL COUNT DECREASED 564 0.0202
729 PAIN OF SKIN 526 0.0200
730 EYE HAEMORRHAGE 261 0.0200
731 RENAL DISORDER 908 0.0200
732 WHITE BLOOD CELL COUNT DECREASED 2089 0.0198
733 ATELECTASIS 187 0.0198
734 PNEUMOCYSTIS JIROVECII PNEUMONIA 191 0.0198
735 ABORTION SPONTANEOUS 775 0.0197
736 DEVICE RELATED INFECTION 296 0.0197
737 BLADDER DISORDER 190 0.0196
738 PRESYNCOPE 456 0.0195
739 MOVEMENT DISORDER 612 0.0195
740 ABDOMINAL PAIN 4373 0.0194
741 OCULAR HYPERAEMIA 868 0.0193
742 BONE DENSITY DECREASED 597 0.0192
743 CORONARY ARTERY OCCLUSION 258 0.0191
744 THROMBOSIS 1499 0.0191
745 ABDOMINAL DISTENSION 1909 0.0190
746 CRYING 678 0.0190
747 QUALITY OF LIFE DECREASED 249 0.0190
748 PERIPHERAL COLDNESS 252 0.0188
749 TINNITUS 842 0.0188
750 GASTROENTERITIS 265 0.0187
751 EPISTAXIS 1365 0.0187
752 MYALGIA 3091 0.0187
753 POOR QUALITY SLEEP 387 0.0187
754 EYE PRURITUS 585 0.0186
755 MULTIPLE FRACTURES 300 0.0185
756 DYSURIA 655 0.0183
757 PNEUMONITIS 476 0.0182
758 COLITIS 661 0.0182
759 VERTIGO 1074 0.0181
760 BLOOD PRESSURE INCREASED 2679 0.0180
761 BLOOD PRESSURE FLUCTUATION 420 0.0179
762 GASTRITIS 458 0.0179
763 CHEST DISCOMFORT 1763 0.0178
764 ACNE 1325 0.0178
765 FEAR 469 0.0177
766 HYPOTHYROIDISM 544 0.0176
767 NERVOUS SYSTEM DISORDER 536 0.0175
768 PNEUMOTHORAX 268 0.0174
769 HAEMORRHOIDS 330 0.0174
770 DEPRESSED MOOD 882 0.0173
771 RECTAL HAEMORRHAGE 726 0.0173
772 HEAD INJURY 524 0.0171
773 INSURANCE ISSUE 233 0.0170
774 EYELID OEDEMA 195 0.0170
775 MUSCLE TWITCHING 382 0.0170
776 MENORRHAGIA 331 0.0168
777 NEUTROPHIL COUNT INCREASED 169 0.0168
778 SPLENOMEGALY 191 0.0168
779 BLOOD COUNT ABNORMAL 255 0.0168
780 MEDICATION ERROR 903 0.0168
781 MUSCLE ATROPHY 202 0.0167
782 FEELING JITTERY 308 0.0165
783 PANCREATITIS 843 0.0164
784 INTESTINAL PERFORATION 178 0.0163
785 CLOSTRIDIUM DIFFICILE INFECTION 341 0.0163
786 TRANSAMINASES INCREASED 352 0.0163
787 POLYNEUROPATHY 186 0.0162
788 EATING DISORDER 336 0.0161
789 ANXIETY 4479 0.0161
790 CARDIAC DISORDER 1470 0.0161
791 BLOOD PRESSURE SYSTOLIC INCREASED 306 0.0160
792 COLITIS ULCERATIVE 686 0.0160
793 NEUROPATHY PERIPHERAL 1451 0.0159
794 HOSPITALISATION 2322 0.0158
795 FREQUENT BOWEL MOVEMENTS 411 0.0158
796 HAEMATOCRIT DECREASED 309 0.0158
797 PLEURAL EFFUSION 935 0.0158
798 CHOLECYSTITIS 181 0.0157
799 MICTURITION URGENCY 173 0.0157
800 TRANSIENT ISCHAEMIC ATTACK 519 0.0157
801 LIP SWELLING 507 0.0157
802 PALLOR 418 0.0157
803 SWOLLEN TONGUE 478 0.0157
804 MYOCARDIAL INFARCTION 2685 0.0156
805 BREAST CANCER FEMALE 411 0.0156
806 COLD SWEAT 267 0.0155
807 BLOOD GLUCOSE ABNORMAL 278 0.0155
808 EXTRA DOSE ADMINISTERED 591 0.0155
809 HOT FLUSH 1133 0.0154
810 HYPOPHAGIA 375 0.0153
811 DEVICE MECHANICAL ISSUE 178 0.0152
812 PRODUCT DISPENSING ERROR 320 0.0151
813 HAEMATEMESIS 374 0.0151
814 DEVICE DEFECTIVE 220 0.0150
815 LOSS OF CONSCIOUSNESS 1865 0.0149
816 PARALYSIS 209 0.0149
817 POLLAKIURIA 602 0.0149
818 THROAT TIGHTNESS 391 0.0149
819 TOOTH LOSS 303 0.0148
820 DISEASE RECURRENCE 688 0.0148
821 ANGINA PECTORIS 416 0.0148
822 HYPERLIPIDAEMIA 172 0.0147
823 COVID-19 2552 0.0147
824 HYPOAESTHESIA ORAL 215 0.0147
825 HYPERSOMNIA 407 0.0146
826 COORDINATION ABNORMAL 200 0.0146
827 BLINDNESS UNILATERAL 199 0.0146
828 SENSORY DISTURBANCE 228 0.0145
829 DRUG RESISTANCE 361 0.0145
830 ALTERED STATE OF CONSCIOUSNESS 301 0.0144
831 HAEMATURIA 482 0.0144
832 BLOOD CREATININE INCREASED 914 0.0143
833 RESTLESS LEGS SYNDROME 252 0.0142
834 PULMONARY EMBOLISM 1319 0.0142
835 DEMENTIA 380 0.0141
836 ASCITES 400 0.0140
837 RENAL IMPAIRMENT 1132 0.0140
838 BALANCE DISORDER 1175 0.0139
839 LETHARGY 774 0.0138
840 PROCEDURAL PAIN 369 0.0138
841 DEEP VEIN THROMBOSIS 876 0.0137
842 CEREBROVASCULAR ACCIDENT 2275 0.0137
843 DRY SKIN 1728 0.0137
844 PERICARDIAL EFFUSION 305 0.0137
845 MOOD ALTERED 358 0.0136
846 SYNCOPE 1315 0.0135
847 THERAPY PARTIAL RESPONDER 191 0.0135
848 THERAPEUTIC RESPONSE SHORTENED 399 0.0135
849 CARDIAC FAILURE CONGESTIVE 1062 0.0133
850 RASH MACULO-PAPULAR 285 0.0133
851 DRUG DISPENSING ERROR 202 0.0132
852 BLOOD POTASSIUM INCREASED 205 0.0130
853 PARAESTHESIA ORAL 181 0.0130
854 PALPITATIONS 1460 0.0129
855 CARDIOMYOPATHY 186 0.0129
856 ATRIAL FIBRILLATION 1218 0.0129
857 BLOOD POTASSIUM DECREASED 376 0.0128
858 HEPATIC FUNCTION ABNORMAL 459 0.0128
859 ECZEMA 590 0.0127
860 MULTI-ORGAN FAILURE 219 0.0126
861 RETCHING 260 0.0126
862 MOOD SWINGS 389 0.0125
863 HAEMATOMA 316 0.0124
864 BRONCHOSPASM 173 0.0124
865 TACHYCARDIA 1070 0.0124
866 CARDIAC FAILURE 949 0.0122
867 HAEMOGLOBIN DECREASED 1219 0.0122
868 RENAL FAILURE 1586 0.0121
869 DYSPNOEA EXERTIONAL 438 0.0121
870 THERAPEUTIC RESPONSE UNEXPECTED 521 0.0119
871 HEART RATE IRREGULAR 263 0.0118
872 BLOOD TRIGLYCERIDES INCREASED 204 0.0118
873 COMA 548 0.0118
874 EMOTIONAL DISORDER 356 0.0117
875 DYSPHAGIA 1067 0.0116
876 ANAEMIA 2123 0.0114
877 PREMATURE BABY 337 0.0114
878 PANIC ATTACK 402 0.0113
879 ANAPHYLACTIC SHOCK 280 0.0113
880 HAEMOPTYSIS 307 0.0113
881 FAECES DISCOLOURED 237 0.0112
882 TREMOR 1814 0.0112
883 PROTEINURIA 203 0.0111
884 DRUG ADMINISTRATION ERROR 341 0.0111
885 CYTOMEGALOVIRUS INFECTION 179 0.0111
886 HAEMATOCHEZIA 592 0.0111
887 INCORRECT ROUTE OF DRUG ADMINISTRATION 394 0.0110
888 HYPOCALCAEMIA 201 0.0110
889 URINARY INCONTINENCE 317 0.0110
890 ABDOMINAL PAIN LOWER 270 0.0110
891 INCREASED APPETITE 193 0.0109
892 SOMNOLENCE 2124 0.0109
893 PLATELET COUNT DECREASED 1124 0.0109
894 METASTASES TO LIVER 184 0.0108
895 MENTAL DISORDER 455 0.0107
896 DYSGEUSIA 778 0.0106
897 ARRHYTHMIA 492 0.0106
898 PULMONARY OEDEMA 462 0.0106
899 SPEECH DISORDER 538 0.0105
900 THINKING ABNORMAL 193 0.0105
901 HAEMORRHAGE 1067 0.0105
902 EYE IRRITATION 543 0.0103
903 THIRST 178 0.0103
904 MUCOSAL INFLAMMATION 260 0.0103
905 PROSTATE CANCER 819 0.0103
906 HEART RATE INCREASED 984 0.0103
907 THROMBOCYTOPENIA 1097 0.0101
908 BLOOD ALKALINE PHOSPHATASE INCREASED 244 0.0100
909 PELVIC PAIN 175 0.0099
910 CHOKING 186 0.0099
911 CARDIOVASCULAR DISORDER 245 0.0098
912 PRODUCT ADMINISTRATION ERROR 187 0.0097
913 COGNITIVE DISORDER 437 0.0097
914 CORONARY ARTERY DISEASE 288 0.0096
915 INTESTINAL OBSTRUCTION 341 0.0094
916 DEHYDRATION 1221 0.0094
917 BLOOD SODIUM DECREASED 172 0.0094
918 PULMONARY HYPERTENSION 187 0.0092
919 CARDIO-RESPIRATORY ARREST 378 0.0092
920 RESPIRATORY FAILURE 649 0.0091
921 FOETAL EXPOSURE DURING PREGNANCY 721 0.0091
922 TREATMENT NONCOMPLIANCE 475 0.0090
923 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 499 0.0090
924 INCORRECT DOSE ADMINISTERED 1949 0.0090
925 FLATULENCE 488 0.0089
926 HEART RATE DECREASED 305 0.0089
927 GLYCOSYLATED HAEMOGLOBIN INCREASED 215 0.0088
928 PERITONITIS 176 0.0087
929 SKIN IRRITATION 390 0.0087
930 OSTEONECROSIS 281 0.0086
931 DEVICE LEAKAGE 343 0.0086
932 CONVULSION 490 0.0086
933 CHROMATURIA 188 0.0086
934 PANCYTOPENIA 461 0.0085
935 BLOOD GLUCOSE DECREASED 396 0.0084
936 PRODUCT PRESCRIBING ERROR 191 0.0084
937 MENTAL IMPAIRMENT 199 0.0084
938 HYPOKALAEMIA 369 0.0083
939 VAGINAL HAEMORRHAGE 345 0.0083
940 CONSTIPATION 1715 0.0082
941 PRODUCT DOSE OMISSION ISSUE 2161 0.0081
942 DISTURBANCE IN ATTENTION 425 0.0080
943 GAMMA-GLUTAMYLTRANSFERASE INCREASED 173 0.0080
944 ANGIOEDEMA 342 0.0080
945 ACUTE MYOCARDIAL INFARCTION 229 0.0079
946 WRONG TECHNIQUE IN DEVICE USAGE PROCESS 347 0.0079
947 FLUSHING 784 0.0079
948 IRRITABILITY 457 0.0078
949 OXYGEN SATURATION DECREASED 416 0.0077
950 PANCREATIC CARCINOMA 218 0.0077
951 DEATH 6352 0.0076
952 ANGER 250 0.0075
953 APHASIA 220 0.0075
954 GASTRIC CANCER 187 0.0074
955 HEPATIC FAILURE 215 0.0073
956 NEUTROPENIA 952 0.0072
957 MULTIPLE ORGAN DYSFUNCTION SYNDROME 191 0.0072
958 CEREBRAL INFARCTION 169 0.0071
959 BLOOD GLUCOSE INCREASED 1276 0.0069
960 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 1156 0.0069
961 DISORIENTATION 266 0.0069
962 PRODUCT QUALITY ISSUE 888 0.0067
963 HYPOTENSION 1301 0.0067
964 BLADDER CANCER 390 0.0066
965 BLOOD PRESSURE DECREASED 424 0.0066
966 SKIN BURNING SENSATION 431 0.0062
967 OVERDOSE 1314 0.0062
968 CEREBRAL HAEMORRHAGE 214 0.0061
969 DRUG EXPOSURE DURING PREGNANCY 204 0.0060
970 DYSARTHRIA 213 0.0058
971 RESTLESSNESS 207 0.0058
972 RENAL FAILURE ACUTE 246 0.0058
973 DISEASE PROGRESSION 660 0.0058
974 SUICIDAL IDEATION 514 0.0058
975 RENAL CANCER 272 0.0057
976 DYSKINESIA 224 0.0057
977 URINARY RETENTION 174 0.0054
978 DRUG INTERACTION 803 0.0052
979 SEIZURE 568 0.0051
980 GASTROINTESTINAL HAEMORRHAGE 412 0.0050
981 CARDIAC ARREST 390 0.0048
982 NEUTROPHIL COUNT DECREASED 182 0.0046
983 AGITATION 287 0.0040
984 HALLUCINATION 272 0.0038
985 ACUTE KIDNEY INJURY 516 0.0035
986 CHRONIC KIDNEY DISEASE 262 0.0035
987 TOXICITY TO VARIOUS AGENTS 507 0.0031
988 NO ADVERSE EVENT 489 0.0029
989 DRUG DEPENDENCE 438 0.0027
990 EMOTIONAL DISTRESS 325 0.0027