SIMVASTATIN

SIMVASTATIN was reported 201669 times

SIMVASTATIN is most commonly taken among patients reporting these side effects:

# Side effect Count Frequency
0 CHRONIC KIDNEY DISEASE-MINERAL AND BONE DISORDER 133 0.2121
1 MYOPATHY 1110 0.1903
2 HYPERPARATHYROIDISM SECONDARY 309 0.1797
3 NEPHROGENIC ANAEMIA 551 0.1712
4 RHABDOMYOLYSIS 4808 0.1670
5 SELF ESTEEM DECREASED 181 0.1476
6 MYOSITIS 648 0.1226
7 REBOUND ACID HYPERSECRETION 307 0.1186
8 BLOOD CREATINE PHOSPHOKINASE INCREASED 2149 0.0955
9 AORTIC ARTERIOSCLEROSIS 157 0.0927
10 LEFT VENTRICULAR HYPERTROPHY 272 0.0918
11 ISCHAEMIC CARDIOMYOPATHY 232 0.0898
12 CORONARY ARTERY STENOSIS 352 0.0894
13 HAEMORRHAGIC ANAEMIA 402 0.0891
14 DIABETIC NEUROPATHY 334 0.0858
15 ACTINIC KERATOSIS 156 0.0856
16 CAROTID ARTERY STENOSIS 225 0.0829
17 END STAGE RENAL DISEASE 1038 0.0782
18 DIASTOLIC DYSFUNCTION 156 0.0781
19 ARTERIOSCLEROSIS CORONARY ARTERY 360 0.0777
20 ORTHOPNOEA 177 0.0774
21 HYPERLIPIDAEMIA 697 0.0762
22 RENAL FAILURE ACUTE 3271 0.0757
23 ANGINA UNSTABLE 397 0.0721
24 CORONARY ARTERY DISEASE 1855 0.0719
25 ESSENTIAL HYPERTENSION 119 0.0701
26 MITRAL VALVE INCOMPETENCE 567 0.0701
27 MUSCLE INJURY 163 0.0697
28 LEFT VENTRICULAR FAILURE 163 0.0696
29 MUSCLE RUPTURE 170 0.0692
30 PERIPHERAL ARTERIAL OCCLUSIVE DISEASE 190 0.0689
31 CAROTID ARTERY OCCLUSION 170 0.0679
32 RENAL FAILURE CHRONIC 525 0.0675
33 MUSCLE ATROPHY 513 0.0665
34 BUNDLE BRANCH BLOCK LEFT 207 0.0662
35 HIGH DENSITY LIPOPROTEIN DECREASED 174 0.0660
36 LABELLED DRUG-DRUG INTERACTION MEDICATION ERROR 389 0.0655
37 CHRONIC KIDNEY DISEASE 3423 0.0655
38 ATRIOVENTRICULAR BLOCK FIRST DEGREE 216 0.0654
39 DYSLIPIDAEMIA 205 0.0653
40 DUODENITIS 139 0.0652
41 VENTRICULAR HYPOKINESIA 140 0.0647
42 TRICUSPID VALVE INCOMPETENCE 345 0.0635
43 LOWER GASTROINTESTINAL HAEMORRHAGE 367 0.0635
44 NORMOCHROMIC NORMOCYTIC ANAEMIA 137 0.0624
45 SPINAL OSTEOARTHRITIS 385 0.0622
46 UPPER GASTROINTESTINAL HAEMORRHAGE 756 0.0621
47 PERIPHERAL VASCULAR DISORDER 259 0.0620
48 AORTIC STENOSIS 150 0.0618
49 DIVERTICULUM 372 0.0617
50 ARTERIOSCLEROSIS 403 0.0617
51 MYALGIA 7045 0.0611
52 CORONARY ARTERY OCCLUSION 659 0.0602
53 AORTIC VALVE INCOMPETENCE 184 0.0601
54 SUBDURAL HAEMORRHAGE 122 0.0599
55 POTENTIATING DRUG INTERACTION 126 0.0599
56 DIABETIC RETINOPATHY 134 0.0589
57 MYOCARDIAL ISCHAEMIA 549 0.0588
58 PSYCHIATRIC SYMPTOM 297 0.0587
59 UROSEPSIS 337 0.0579
60 TENDON RUPTURE 532 0.0577
61 ABNORMAL LOSS OF WEIGHT 270 0.0577
62 TENDERNESS 399 0.0571
63 DRUG INTERACTION 6023 0.0562
64 HYPOVOLAEMIA 230 0.0559
65 ATRIAL FLUTTER 318 0.0558
66 ACUTE MYOCARDIAL INFARCTION 1240 0.0558
67 RENAL INJURY 1299 0.0557
68 SUPRAVENTRICULAR EXTRASYSTOLES 139 0.0556
69 VENTRICULAR HYPERTROPHY 123 0.0552
70 INTERNATIONAL NORMALISED RATIO INCREASED 1389 0.0550
71 HYPERKALAEMIA 1284 0.0550
72 SOCIAL PROBLEM 161 0.0546
73 BLOOD CHOLESTEROL ABNORMAL 157 0.0546
74 ACUTE KIDNEY INJURY 4542 0.0545
75 LUMBAR SPINAL STENOSIS 118 0.0545
76 ISCHAEMIA 188 0.0544
77 NON-CARDIAC CHEST PAIN 140 0.0537
78 SINUS BRADYCARDIA 357 0.0537
79 ACUTE CORONARY SYNDROME 335 0.0535
80 ORTHOSTATIC HYPOTENSION 599 0.0529
81 DUODENAL ULCER HAEMORRHAGE 116 0.0527
82 DIABETES MELLITUS INADEQUATE CONTROL 621 0.0525
83 RENAL CYST 287 0.0522
84 LEFT VENTRICULAR DYSFUNCTION 225 0.0520
85 GLOMERULAR FILTRATION RATE DECREASED 311 0.0520
86 AZOTAEMIA 138 0.0519
87 HEPATIC CYST 119 0.0518
88 ANGINA PECTORIS 1099 0.0516
89 DIVERTICULUM INTESTINAL 152 0.0515
90 INTERNATIONAL NORMALISED RATIO DECREASED 189 0.0513
91 FRUSTRATION 182 0.0503
92 BLOOD CHOLESTEROL INCREASED 1531 0.0502
93 BENIGN PROSTATIC HYPERPLASIA 181 0.0502
94 QUALITY OF LIFE DECREASED 428 0.0502
95 ELECTROCARDIOGRAM ABNORMAL 265 0.0498
96 TYPE 2 DIABETES MELLITUS 1160 0.0497
97 RHINITIS ALLERGIC 124 0.0494
98 NOCTURIA 354 0.0490
99 CARDIOMEGALY 482 0.0490
100 IRON DEFICIENCY ANAEMIA 304 0.0490
101 OESOPHAGITIS 365 0.0487
102 GLUCOSE TOLERANCE IMPAIRED 177 0.0487
103 ATELECTASIS 348 0.0485
104 BLOOD UREA INCREASED 646 0.0481
105 GASTRITIS EROSIVE 170 0.0481
106 HYPONATRAEMIA 1824 0.0480
107 DUODENAL ULCER 240 0.0479
108 ATRIAL FIBRILLATION 2942 0.0479
109 MUSCLE DISORDER 287 0.0479
110 JAUNDICE CHOLESTATIC 121 0.0478
111 RENAL FAILURE 4577 0.0477
112 SLEEP APNOEA SYNDROME 621 0.0476
113 RALES 174 0.0476
114 CEREBRAL ISCHAEMIA 193 0.0474
115 GOUT 546 0.0474
116 TROPONIN INCREASED 191 0.0470
117 TRANSIENT ISCHAEMIC ATTACK 1186 0.0470
118 MELAENA 712 0.0466
119 HIATUS HERNIA 446 0.0465
120 ATRIOVENTRICULAR BLOCK COMPLETE 210 0.0464
121 SUBDURAL HAEMATOMA 490 0.0463
122 CIRCULATORY COLLAPSE 589 0.0460
123 INTERVERTEBRAL DISC DEGENERATION 309 0.0460
124 SPINAL COLUMN STENOSIS 221 0.0459
125 THERAPEUTIC AGENT TOXICITY 157 0.0459
126 LIVER FUNCTION TEST ABNORMAL 1105 0.0459
127 VENTRICULAR EXTRASYSTOLES 346 0.0457
128 BLOOD POTASSIUM INCREASED 508 0.0456
129 BUNDLE BRANCH BLOCK RIGHT 162 0.0456
130 NEPHROPATHY 258 0.0453
131 RENAL TUBULAR NECROSIS 283 0.0452
132 BLOOD CREATINE INCREASED 126 0.0451
133 ARTERIAL OCCLUSIVE DISEASE 263 0.0450
134 BLOOD PRESSURE INADEQUATELY CONTROLLED 230 0.0449
135 GASTROINTESTINAL HAEMORRHAGE 3017 0.0449
136 SOCIAL AVOIDANT BEHAVIOUR 214 0.0448
137 LACTIC ACIDOSIS 809 0.0447
138 HYPOMAGNESAEMIA 356 0.0446
139 BREATH SOUNDS ABNORMAL 124 0.0446
140 OESOPHAGEAL ULCER 127 0.0446
141 CEREBRAL ATROPHY 132 0.0441
142 NEUTROPENIC SEPSIS 216 0.0441
143 LOW DENSITY LIPOPROTEIN INCREASED 218 0.0439
144 OEDEMA MOUTH 136 0.0439
145 PANCREATITIS ACUTE 623 0.0439
146 HYPOGLYCAEMIA 1518 0.0436
147 EXERCISE TOLERANCE DECREASED 147 0.0430
148 MUSCULAR WEAKNESS 3266 0.0429
149 PERIPHERAL ISCHAEMIA 119 0.0429
150 TYPE 1 DIABETES MELLITUS 153 0.0427
151 POLYNEUROPATHY 268 0.0424
152 DYSPNOEA EXERTIONAL 916 0.0423
153 OSTEOARTHRITIS 1111 0.0423
154 HAEMATURIA 1047 0.0422
155 BLOOD TRIGLYCERIDES INCREASED 553 0.0421
156 AORTIC ANEURYSM 242 0.0418
157 VENTRICULAR TACHYCARDIA 464 0.0414
158 HEMIPARESIS 519 0.0413
159 PULMONARY FIBROSIS 463 0.0413
160 ATRIOVENTRICULAR BLOCK 211 0.0412
161 VITAMIN D DEFICIENCY 246 0.0411
162 ELECTROLYTE IMBALANCE 288 0.0410
163 EXTRASYSTOLES 210 0.0409
164 EXOSTOSIS 242 0.0408
165 CHRONIC OBSTRUCTIVE PULMONARY DISEASE 1447 0.0407
166 PEMPHIGOID 159 0.0407
167 COAGULOPATHY 478 0.0405
168 TUBULOINTERSTITIAL NEPHRITIS 464 0.0405
169 INTESTINAL ISCHAEMIA 150 0.0402
170 GASTRITIS 722 0.0401
171 HAIR DISORDER 294 0.0401
172 CARDIAC VALVE DISEASE 162 0.0400
173 HAEMODIALYSIS 312 0.0399
174 DIFFICULTY IN WALKING 137 0.0398
175 BRADYCARDIA 1431 0.0396
176 BLOOD CREATININE INCREASED 1757 0.0395
177 CARPAL TUNNEL SYNDROME 355 0.0394
178 SYNCOPE 2695 0.0394
179 CARDIAC FAILURE ACUTE 148 0.0394
180 MULTIPLE INJURIES 234 0.0393
181 ISCHAEMIC STROKE 491 0.0393
182 HAEMATEMESIS 710 0.0393
183 OSTEOPENIA 331 0.0392
184 ECCHYMOSIS 200 0.0391
185 HYPERGLYCAEMIA 973 0.0391
186 OBESITY 379 0.0390
187 CORONARY ARTERIAL STENT INSERTION 152 0.0389
188 HYPOKALAEMIA 1138 0.0389
189 STENT PLACEMENT 230 0.0388
190 BLOOD MAGNESIUM DECREASED 196 0.0387
191 CARDIAC MURMUR 265 0.0386
192 PROTHROMBIN TIME PROLONGED 199 0.0386
193 NEPHROGENIC SYSTEMIC FIBROSIS 118 0.0386
194 BODY HEIGHT DECREASED 324 0.0385
195 BURSITIS 253 0.0384
196 PSYCHOLOGICAL TRAUMA 299 0.0384
197 BLOOD SODIUM DECREASED 472 0.0383
198 CARDIAC FAILURE CONGESTIVE 2601 0.0383
199 CORONARY ARTERY BYPASS 176 0.0380
200 CHROMATURIA 606 0.0379
201 HAIR COLOUR CHANGES 359 0.0378
202 EMPHYSEMA 273 0.0377
203 ROTATOR CUFF SYNDROME 335 0.0375
204 VENTRICULAR FIBRILLATION 298 0.0373
205 NEUTROPHIL COUNT INCREASED 260 0.0373
206 FAECALOMA 126 0.0373
207 BLOOD URINE PRESENT 495 0.0373
208 GINGIVITIS 139 0.0372
209 FLUSHING 2807 0.0372
210 DIZZINESS POSTURAL 193 0.0372
211 GASTRIC ULCER 501 0.0370
212 HYPERTENSIVE CRISIS 286 0.0370
213 RENAL IMPAIRMENT 1791 0.0369
214 CARDIOGENIC SHOCK 298 0.0368
215 SUPRAVENTRICULAR TACHYCARDIA 247 0.0367
216 BLOOD ALBUMIN DECREASED 210 0.0366
217 COLITIS ISCHAEMIC 163 0.0366
218 VARICOSE VEIN 128 0.0365
219 HAEMATOMA 672 0.0365
220 BASAL CELL CARCINOMA 357 0.0364
221 SQUAMOUS CELL CARCINOMA OF SKIN 121 0.0362
222 URINE OUTPUT DECREASED 233 0.0362
223 BLOOD GLUCOSE FLUCTUATION 286 0.0361
224 HAEMATOCRIT DECREASED 540 0.0360
225 PULMONARY HYPERTENSION 536 0.0359
226 FAECES DISCOLOURED 535 0.0358
227 GENERAL PHYSICAL HEALTH DETERIORATION 2221 0.0357
228 MICTURITION URGENCY 259 0.0357
229 HAEMORRHAGIC STROKE 210 0.0357
230 BLOOD PRESSURE DIASTOLIC DECREASED 136 0.0356
231 ACUTE RESPIRATORY FAILURE 386 0.0356
232 CARDIAC PACEMAKER INSERTION 149 0.0355
233 PRODUCT PRESCRIBING ERROR 268 0.0354
234 GROIN PAIN 215 0.0354
235 BALANCE DISORDER 2062 0.0354
236 OEDEMA PERIPHERAL 3288 0.0353
237 EJECTION FRACTION DECREASED 324 0.0353
238 RECTAL HAEMORRHAGE 1064 0.0350
239 CONFUSIONAL STATE 3840 0.0350
240 INCREASED TENDENCY TO BRUISE 227 0.0349
241 DERMATITIS EXFOLIATIVE 157 0.0349
242 HAEMORRHAGE INTRACRANIAL 406 0.0348
243 PATHOLOGICAL FRACTURE 118 0.0348
244 PULMONARY CONGESTION 302 0.0346
245 ERECTILE DYSFUNCTION 565 0.0345
246 DIABETES MELLITUS 1849 0.0345
247 LUNG INFILTRATION 251 0.0345
248 TENDONITIS 385 0.0344
249 ACIDOSIS 183 0.0344
250 HYPERKERATOSIS 122 0.0343
251 HAEMATOCHEZIA 1028 0.0342
252 CARDIOMYOPATHY 354 0.0340
253 RHINITIS 168 0.0339
254 URINARY INCONTINENCE 686 0.0339
255 CLOSTRIDIUM DIFFICILE COLITIS 232 0.0338
256 TORSADE DE POINTES 186 0.0338
257 FALL 7272 0.0337
258 HAEMORRHOIDS 442 0.0337
259 SUBARACHNOID HAEMORRHAGE 233 0.0337
260 ECONOMIC PROBLEM 470 0.0336
261 HAIR TEXTURE ABNORMAL 357 0.0335
262 HEPATIC STEATOSIS 406 0.0334
263 HEMIPLEGIA 200 0.0333
264 ACTIVITIES OF DAILY LIVING IMPAIRED 668 0.0333
265 GLYCOSYLATED HAEMOGLOBIN INCREASED 497 0.0331
266 ANURIA 215 0.0331
267 CATARACT 1133 0.0330
268 ANAL INCONTINENCE 132 0.0330
269 AUTOIMMUNE HEPATITIS 140 0.0330
270 JOINT EFFUSION 147 0.0330
271 MULTIPLE FRACTURES 161 0.0330
272 HAEMOPTYSIS 644 0.0330
273 POLYP 137 0.0329
274 PRESYNCOPE 515 0.0329
275 MENTAL STATUS CHANGES 649 0.0329
276 MULTI-ORGAN FAILURE 579 0.0328
277 CHEST PAIN 4285 0.0328
278 GASTROOESOPHAGEAL REFLUX DISEASE 1678 0.0327
279 FAECAL INCONTINENCE 160 0.0327
280 SCIATICA 281 0.0327
281 UNRESPONSIVE TO STIMULI 562 0.0325
282 FLANK PAIN 199 0.0324
283 HYPOPHAGIA 510 0.0324
284 GASTROENTERITIS 320 0.0324
285 POLYURIA 174 0.0324
286 GASTRIC ULCER HAEMORRHAGE 143 0.0322
287 DEHYDRATION 2966 0.0322
288 AMNESIA 1488 0.0320
289 INFARCTION 169 0.0320
290 METABOLIC ACIDOSIS 603 0.0320
291 WALKING AID USER 127 0.0319
292 HYPOTENSION 4127 0.0319
293 INCONTINENCE 229 0.0319
294 OLIGURIA 139 0.0318
295 JOINT DISLOCATION 204 0.0318
296 ABASIA 793 0.0317
297 CEREBRAL HAEMORRHAGE 797 0.0317
298 MACULAR DEGENERATION 219 0.0316
299 SKIN HAEMORRHAGE 213 0.0316
300 MUSCULOSKELETAL PAIN 1421 0.0316
301 LETHARGY 1272 0.0315
302 BLOOD TESTOSTERONE DECREASED 178 0.0315
303 DECUBITUS ULCER 180 0.0315
304 SQUAMOUS CELL CARCINOMA 186 0.0315
305 INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION 207 0.0315
306 WOUND 397 0.0315
307 URINARY RETENTION 680 0.0314
308 INTERVERTEBRAL DISC PROTRUSION 482 0.0314
309 DYSARTHRIA 828 0.0314
310 PERONEAL NERVE PALSY 125 0.0314
311 LEUKOCYTOSIS 375 0.0314
312 MYOCARDIAL INFARCTION 4480 0.0313
313 HEART RATE IRREGULAR 507 0.0313
314 MUSCLE STRAIN 176 0.0313
315 EPISTAXIS 1594 0.0312
316 OSTEOPOROSIS 734 0.0312
317 MOUTH HAEMORRHAGE 145 0.0311
318 CEREBRAL INFARCTION 537 0.0310
319 HYPOTHERMIA 214 0.0310
320 SKIN CANCER 268 0.0309
321 ANAEMIA 3937 0.0307
322 INCREASED UPPER AIRWAY SECRETION 133 0.0307
323 CATARACT OPERATION 125 0.0306
324 NIGHTMARE 755 0.0306
325 CANDIDIASIS 126 0.0306
326 MUSCULOSKELETAL DISCOMFORT 327 0.0306
327 POLLAKIURIA 837 0.0306
328 DIALYSIS 321 0.0306
329 HEPATITIS CHOLESTATIC 123 0.0306
330 LARGE INTESTINE POLYP 136 0.0305
331 CONTUSION 1854 0.0305
332 COLD SWEAT 370 0.0304
333 PULMONARY OEDEMA 917 0.0303
334 WHITE BLOOD CELL COUNT INCREASED 827 0.0303
335 HAEMOGLOBIN DECREASED 2103 0.0303
336 PROSTATIC SPECIFIC ANTIGEN INCREASED 265 0.0303
337 NERVE COMPRESSION 174 0.0303
338 HEAD INJURY 615 0.0302
339 PERICARDIAL EFFUSION 424 0.0302
340 PLATELET COUNT INCREASED 239 0.0302
341 ASTHENIA 7312 0.0301
342 LIPASE INCREASED 158 0.0301
343 FAILURE TO THRIVE 118 0.0301
344 HAEMARTHROSIS 123 0.0301
345 APHASIA 621 0.0300
346 NECROSIS 120 0.0300
347 BONE DISORDER 414 0.0300
348 RIB FRACTURE 389 0.0299
349 STRESS FRACTURE 123 0.0299
350 MYOCLONUS 243 0.0299
351 SENSORY LOSS 164 0.0298
352 FEELING HOT 1194 0.0298
353 BLOOD CALCIUM DECREASED 226 0.0298
354 JOINT RANGE OF MOTION DECREASED 201 0.0297
355 MUSCLE SPASMS 3652 0.0297
356 CONTRAINDICATED PRODUCT ADMINISTERED 329 0.0297
357 SENSATION OF HEAVINESS 117 0.0297
358 DIABETIC KETOACIDOSIS 469 0.0296
359 HEPATOMEGALY 218 0.0296
360 WRIST FRACTURE 227 0.0296
361 PAIN IN EXTREMITY 5889 0.0296
362 CEREBROVASCULAR ACCIDENT 3663 0.0296
363 BLOOD POTASSIUM DECREASED 584 0.0295
364 SWOLLEN TONGUE 655 0.0295
365 PALLOR 498 0.0295
366 DYSURIA 740 0.0293
367 PARKINSONISM 178 0.0293
368 ERUCTATION 311 0.0293
369 AGEUSIA 458 0.0293
370 PLEURAL EFFUSION 1221 0.0293
371 DIVERTICULITIS 509 0.0292
372 SHOCK HAEMORRHAGIC 148 0.0292
373 POSTOPERATIVE WOUND INFECTION 118 0.0292
374 PETECHIAE 205 0.0292
375 ATAXIA 244 0.0290
376 CHOLECYSTITIS ACUTE 117 0.0290
377 VITAMIN D DECREASED 165 0.0289
378 GLAUCOMA 363 0.0289
379 GAIT DISTURBANCE 3686 0.0289
380 BLOOD CALCIUM INCREASED 174 0.0287
381 HALLUCINATION, VISUAL 357 0.0287
382 INITIAL INSOMNIA 179 0.0287
383 ALANINE AMINOTRANSFERASE INCREASED 1250 0.0287
384 HYPERTENSION 3830 0.0287
385 ARRHYTHMIA 956 0.0286
386 DELIRIUM 609 0.0286
387 BLOOD PRESSURE SYSTOLIC INCREASED 292 0.0286
388 SINUS TACHYCARDIA 276 0.0285
389 URINARY TRACT INFECTION 2915 0.0284
390 CARDIAC FLUTTER 118 0.0284
391 MUSCULOSKELETAL CHEST PAIN 284 0.0283
392 CARDIAC FAILURE 1460 0.0283
393 LIP SWELLING 623 0.0283
394 CELLULITIS 973 0.0283
395 HEART RATE DECREASED 558 0.0282
396 DYSSTASIA 540 0.0282
397 ANHEDONIA 485 0.0282
398 HYPOXIA 602 0.0282
399 DYSPEPSIA 1765 0.0281
400 ELECTROCARDIOGRAM QT PROLONGED 625 0.0281
401 IMPAIRED HEALING 564 0.0281
402 ESCHERICHIA INFECTION 135 0.0280
403 LOCAL SWELLING 488 0.0278
404 POST PROCEDURAL HAEMORRHAGE 235 0.0277
405 BLOOD ALKALINE PHOSPHATASE INCREASED 537 0.0277
406 PANCREATITIS 1036 0.0277
407 NECK PAIN 1000 0.0277
408 HYDRONEPHROSIS 135 0.0276
409 PERIPHERAL COLDNESS 253 0.0275
410 ORAL CANDIDIASIS 219 0.0275
411 HAND FRACTURE 117 0.0274
412 FEAR 590 0.0274
413 RESTLESS LEGS SYNDROME 337 0.0274
414 PULMONARY MASS 233 0.0274
415 PURPURA 174 0.0273
416 SKIN LACERATION 133 0.0273
417 ORAL PAIN 406 0.0273
418 EYE HAEMORRHAGE 252 0.0273
419 RETINAL HAEMORRHAGE 136 0.0273
420 HYPOKINESIA 261 0.0273
421 NEUROPATHY PERIPHERAL 1426 0.0272
422 MAJOR DEPRESSION 124 0.0272
423 ABNORMAL DREAMS 607 0.0272
424 BLOOD PRESSURE ABNORMAL 290 0.0271
425 HYPOTHYROIDISM 499 0.0271
426 DYSPNOEA 9853 0.0271
427 DRUG-INDUCED LIVER INJURY 366 0.0271
428 SPRUE-LIKE ENTEROPATHY 117 0.0271
429 VITREOUS FLOATERS 150 0.0271
430 ANGIOEDEMA 753 0.0271
431 ULCER HAEMORRHAGE 127 0.0270
432 MOVEMENT DISORDER 585 0.0270
433 BLADDER DISORDER 180 0.0270
434 HYPERCALCAEMIA 213 0.0270
435 ANKLE FRACTURE 271 0.0270
436 POOR QUALITY SLEEP 343 0.0269
437 DEMENTIA 404 0.0268
438 GANGRENE 125 0.0268
439 CONSTIPATION 3369 0.0268
440 CHOLECYSTITIS 219 0.0267
441 FLATULENCE 971 0.0267
442 WEIGHT DECREASED 4653 0.0266
443 DIZZINESS 8715 0.0266
444 ANOREXIA 358 0.0266
445 IMPAIRED QUALITY OF LIFE 149 0.0266
446 MIDDLE INSOMNIA 315 0.0266
447 DYSPHONIA 966 0.0266
448 LACERATION 251 0.0265
449 REFUSAL OF TREATMENT BY PATIENT 127 0.0265
450 JAW DISORDER 116 0.0265
451 LIVER INJURY 265 0.0264
452 SUDDEN DEATH 222 0.0264
453 SPINAL PAIN 176 0.0264
454 DISORIENTATION 775 0.0264
455 BLINDNESS TRANSIENT 126 0.0263
456 DIPLOPIA 448 0.0263
457 DRY MOUTH 1379 0.0263
458 TOOTH ABSCESS 193 0.0263
459 BEDRIDDEN 229 0.0263
460 GAMMA-GLUTAMYLTRANSFERASE INCREASED 446 0.0263
461 LIMB DISCOMFORT 482 0.0263
462 MADAROSIS 253 0.0262
463 HEPATITIS ACUTE 117 0.0262
464 GINGIVAL BLEEDING 224 0.0261
465 COORDINATION ABNORMAL 291 0.0261
466 RESPIRATORY FAILURE 1307 0.0261
467 CHOLELITHIASIS 612 0.0260
468 SPINAL COMPRESSION FRACTURE 153 0.0260
469 SKIN ULCER 440 0.0260
470 SLEEP DISORDER 1009 0.0260
471 DERMATITIS BULLOUS 125 0.0260
472 IRRITABLE BOWEL SYNDROME 293 0.0259
473 HICCUPS 136 0.0259
474 ARTHRITIS 1232 0.0258
475 RETINAL DETACHMENT 153 0.0258
476 PROTEINURIA 280 0.0258
477 SPLENOMEGALY 201 0.0257
478 DYSPHAGIA 1559 0.0257
479 PARALYSIS 251 0.0256
480 RETCHING 353 0.0256
481 HIP FRACTURE 516 0.0255
482 GLOSSODYNIA 271 0.0255
483 BLOOD PRESSURE FLUCTUATION 350 0.0255
484 BLOOD PRESSURE INCREASED 2441 0.0255
485 DRUG LEVEL INCREASED 259 0.0254
486 FIBROMYALGIA 344 0.0254
487 PLEURISY 116 0.0253
488 PELVIC FRACTURE 126 0.0253
489 RENAL DISORDER 741 0.0252
490 WHEEZING 782 0.0252
491 SEPSIS 1844 0.0251
492 FEELING DRUNK 136 0.0251
493 LOSS OF CONSCIOUSNESS 2218 0.0251
494 HYPERHIDROSIS 2224 0.0250
495 PARAESTHESIA 2665 0.0250
496 JOINT INJURY 328 0.0249
497 LIMB INJURY 373 0.0249
498 DECREASED APPETITE 3436 0.0249
499 BLOOD GLUCOSE INCREASED 3375 0.0249
500 PROSTATE CANCER 386 0.0249
501 VASCULITIS 179 0.0248
502 BACK PAIN 3761 0.0248
503 MOBILITY DECREASED 1067 0.0248
504 TONGUE DISORDER 136 0.0248
505 JAUNDICE 514 0.0248
506 HEPATITIS 424 0.0248
507 FOOT FRACTURE 306 0.0247
508 SPEECH DISORDER 886 0.0247
509 TRANSAMINASES INCREASED 361 0.0247
510 RESPIRATORY DISTRESS 477 0.0246
511 ASPARTATE AMINOTRANSFERASE INCREASED 937 0.0246
512 UPPER LIMB FRACTURE 333 0.0245
513 BACK INJURY 152 0.0245
514 PRODUCTIVE COUGH 643 0.0244
515 BLOOD PRESSURE DECREASED 1058 0.0244
516 PERSONALITY CHANGE 171 0.0244
517 COUGH 3980 0.0244
518 CARDIAC DISORDER 1517 0.0244
519 SKIN LESION 402 0.0243
520 MOUTH ULCERATION 314 0.0243
521 CHEST DISCOMFORT 1533 0.0243
522 NEURALGIA 345 0.0242
523 BLINDNESS UNILATERAL 226 0.0242
524 SPINAL DISORDER 145 0.0241
525 OEDEMA 854 0.0241
526 CARDIAC ARREST 1419 0.0241
527 ARTHROPATHY 771 0.0241
528 BLOOD GLUCOSE ABNORMAL 285 0.0240
529 HYPERSOMNIA 438 0.0240
530 IMPAIRED WORK ABILITY 371 0.0240
531 BRONCHITIS 1272 0.0240
532 NIGHT SWEATS 454 0.0239
533 BACK DISORDER 252 0.0239
534 PNEUMONIA ASPIRATION 379 0.0238
535 INTERNAL HAEMORRHAGE 187 0.0238
536 PNEUMONIA 4805 0.0238
537 COGNITIVE DISORDER 686 0.0238
538 THYROID DISORDER 225 0.0238
539 RED BLOOD CELL SEDIMENTATION RATE INCREASED 158 0.0238
540 LOWER RESPIRATORY TRACT INFECTION 594 0.0237
541 ARTHRALGIA 5600 0.0236
542 OSTEOMYELITIS 312 0.0236
543 GINGIVAL PAIN 127 0.0236
544 HYPOCALCAEMIA 286 0.0235
545 BLOOD GLUCOSE DECREASED 836 0.0235
546 C-REACTIVE PROTEIN INCREASED 487 0.0235
547 SEROTONIN SYNDROME 268 0.0235
548 RESPIRATORY RATE INCREASED 135 0.0234
549 DECREASED ACTIVITY 133 0.0234
550 EATING DISORDER 321 0.0234
551 DENTAL CARIES 178 0.0234
552 MUSCLE RIGIDITY 183 0.0233
553 BURNING SENSATION 1112 0.0233
554 CYSTITIS 505 0.0233
555 TOXIC EPIDERMAL NECROLYSIS 228 0.0233
556 DYSGEUSIA 1202 0.0233
557 CARDIAC OPERATION 116 0.0232
558 HALLUCINATION 1066 0.0232
559 FLUID OVERLOAD 322 0.0231
560 MALIGNANT MELANOMA 204 0.0231
561 HEPATIC ENZYME INCREASED 895 0.0231
562 VISUAL FIELD DEFECT 125 0.0230
563 ACUTE RESPIRATORY DISTRESS SYNDROME 265 0.0230
564 BLOOD DISORDER 120 0.0229
565 POST PROCEDURAL COMPLICATION 315 0.0229
566 PALPITATIONS 1784 0.0229
567 FOOT DEFORMITY 156 0.0229
568 DRUG PRESCRIBING ERROR 443 0.0229
569 ACUTE HEPATIC FAILURE 188 0.0229
570 HYPERAESTHESIA 136 0.0229
571 PHOTOSENSITIVITY REACTION 250 0.0229
572 GAIT INABILITY 280 0.0229
573 DEPRESSION 3744 0.0228
574 VISUAL ACUITY REDUCED 649 0.0228
575 NEPHROLITHIASIS 615 0.0228
576 DRY THROAT 148 0.0228
577 DIARRHOEA 8657 0.0227
578 MEMORY IMPAIRMENT 1991 0.0227
579 WOUND INFECTION 128 0.0227
580 SALIVARY HYPERSECRETION 146 0.0227
581 CLOSTRIDIUM DIFFICILE INFECTION 272 0.0226
582 RASH PRURITIC 744 0.0226
583 RED BLOOD CELL COUNT DECREASED 391 0.0226
584 SPUTUM DISCOLOURED 125 0.0226
585 DEAFNESS 348 0.0226
586 SWELLING FACE 983 0.0225
587 HYPOAESTHESIA 2249 0.0225
588 FEELING COLD 406 0.0225
589 SMALL INTESTINAL OBSTRUCTION 178 0.0224
590 TOOTH INFECTION 174 0.0224
591 MALNUTRITION 155 0.0223
592 DIARRHOEA HAEMORRHAGIC 135 0.0223
593 BLISTER 746 0.0223
594 BLOOD IRON DECREASED 135 0.0223
595 NERVE INJURY 164 0.0222
596 FATIGUE 10234 0.0221
597 HEPATOTOXICITY 278 0.0221
598 PRURITUS GENERALISED 483 0.0221
599 HEARING IMPAIRED 133 0.0220
600 MUSCLE TWITCHING 353 0.0220
601 KNEE ARTHROPLASTY 232 0.0220
602 PNEUMONITIS 327 0.0219
603 UPPER RESPIRATORY TRACT INFECTION 655 0.0218
604 INSOMNIA 3986 0.0218
605 FEMUR FRACTURE 498 0.0218
606 MUSCULOSKELETAL STIFFNESS 1157 0.0218
607 PERIPHERAL SWELLING 1780 0.0218
608 FULL BLOOD COUNT DECREASED 232 0.0218
609 ABDOMINAL DISTENSION 1438 0.0218
610 FACIAL PAIN 123 0.0218
611 SENSORY DISTURBANCE 264 0.0218
612 INJURY 1144 0.0217
613 VISION BLURRED 1917 0.0217
614 PANCYTOPENIA 767 0.0216
615 EMOTIONAL DISTRESS 1055 0.0216
616 LACRIMATION INCREASED 359 0.0216
617 HYPERTHYROIDISM 191 0.0216
618 VISUAL DISTURBANCE 132 0.0216
619 RESTLESSNESS 543 0.0216
620 DEEP VEIN THROMBOSIS 1101 0.0216
621 SKIN DISCOLOURATION 652 0.0216
622 NERVOUSNESS 845 0.0215
623 VERTIGO 899 0.0214
624 RENAL PAIN 140 0.0214
625 TREMOR 2465 0.0214
626 IMPAIRED DRIVING ABILITY 178 0.0214
627 JOINT SWELLING 1433 0.0213
628 EAR PAIN 261 0.0213
629 ULCER 219 0.0213
630 LOCALISED INFECTION 316 0.0213
631 MUSCLE TIGHTNESS 237 0.0212
632 DYSKINESIA 586 0.0212
633 ABDOMINAL PAIN UPPER 2736 0.0211
634 RASH ERYTHEMATOUS 548 0.0211
635 GASTROINTESTINAL PAIN 137 0.0211
636 TINNITUS 645 0.0211
637 BLOOD BILIRUBIN INCREASED 416 0.0210
638 KIDNEY INFECTION 250 0.0210
639 TREATMENT NONCOMPLIANCE 651 0.0210
640 STRESS 891 0.0210
641 STAPHYLOCOCCAL INFECTION 500 0.0210
642 NODULE 167 0.0209
643 DELUSION 206 0.0209
644 TACHYCARDIA 1210 0.0209
645 HYPOTONIA 154 0.0209
646 BODY TEMPERATURE INCREASED 285 0.0209
647 GASTRIC HAEMORRHAGE 182 0.0209
648 MASS 196 0.0208
649 ENCEPHALOPATHY 318 0.0208
650 PHARYNGEAL OEDEMA 312 0.0208
651 GALLBLADDER DISORDER 278 0.0208
652 TOOTH FRACTURE 149 0.0207
653 PANCREATIC CARCINOMA 230 0.0207
654 PERICARDITIS 118 0.0207
655 CARDIOVASCULAR DISORDER 444 0.0207
656 BLOOD COUNT ABNORMAL 261 0.0206
657 SECRETION DISCHARGE 134 0.0206
658 RASH MACULAR 427 0.0206
659 FLUID RETENTION 702 0.0206
660 SINUS DISORDER 253 0.0206
661 GENERALISED OEDEMA 165 0.0205
662 PAIN IN JAW 414 0.0204
663 EYE SWELLING 486 0.0204
664 THROMBOSIS 1059 0.0204
665 CHOKING 247 0.0204
666 SOMNOLENCE 2695 0.0204
667 ABDOMINAL PAIN 3053 0.0204
668 SPINAL FRACTURE 243 0.0204
669 SCHIZOPHRENIA 141 0.0203
670 OXYGEN SATURATION DECREASED 583 0.0203
671 ILEUS 166 0.0203
672 RASH MACULO-PAPULAR 277 0.0203
673 PAIN 7062 0.0203
674 PRURITUS 4125 0.0203
675 BIPOLAR DISORDER 164 0.0203
676 ORAL DISCOMFORT 193 0.0203
677 SCAB 143 0.0202
678 HYPOAESTHESIA ORAL 207 0.0202
679 MENTAL IMPAIRMENT 328 0.0202
680 HOT FLUSH 876 0.0201
681 THROMBOCYTOPENIA 1402 0.0201
682 APHONIA 168 0.0201
683 MOTOR DYSFUNCTION 133 0.0200
684 COLITIS 414 0.0200
685 LOWER LIMB FRACTURE 218 0.0200
686 FEELING JITTERY 286 0.0200
687 PLATELET COUNT DECREASED 1279 0.0200
688 PRESCRIBED UNDERDOSE 211 0.0199
689 INJECTION SITE NODULE 160 0.0199
690 VOMITING 5996 0.0199
691 SINUS CONGESTION 178 0.0198
692 HEAD DISCOMFORT 196 0.0198
693 CHILLS 1483 0.0198
694 TOOTHACHE 236 0.0198
695 EAR DISCOMFORT 125 0.0198
696 DISTURBANCE IN ATTENTION 741 0.0197
697 APATHY 192 0.0197
698 DRY EYE 417 0.0197
699 LUNG NEOPLASM MALIGNANT 372 0.0197
700 BACTERAEMIA 131 0.0197
701 CARDIO-RESPIRATORY ARREST 618 0.0196
702 JOINT STIFFNESS 329 0.0196
703 DERMATITIS 230 0.0196
704 ABDOMINAL DISCOMFORT 1900 0.0196
705 DRUG ERUPTION 208 0.0195
706 DERMATITIS ALLERGIC 141 0.0195
707 PULMONARY EMBOLISM 1370 0.0195
708 ANXIETY 3699 0.0195
709 PARANOIA 244 0.0195
710 NAUSEA 9899 0.0195
711 INTRAOCULAR PRESSURE INCREASED 175 0.0194
712 WEIGHT INCREASED 2710 0.0194
713 SINUSITIS 1234 0.0194
714 SHOCK 286 0.0193
715 TACHYPNOEA 153 0.0192
716 MALAISE 5863 0.0192
717 HERNIA 218 0.0192
718 VISUAL IMPAIRMENT 1339 0.0192
719 TOOTH DISORDER 289 0.0192
720 MENTAL DISORDER 503 0.0191
721 CANDIDA INFECTION 168 0.0191
722 SEASONAL ALLERGY 126 0.0190
723 PARAESTHESIA ORAL 170 0.0190
724 EOSINOPHILIA 198 0.0190
725 ECZEMA 282 0.0190
726 OROPHARYNGEAL PAIN 1066 0.0190
727 INTERSTITIAL LUNG DISEASE 554 0.0189
728 RASH GENERALISED 496 0.0189
729 INFLAMMATION 511 0.0189
730 SEXUAL DYSFUNCTION 141 0.0189
731 FEELING ABNORMAL 3127 0.0188
732 ASPIRATION 129 0.0188
733 RHINORRHOEA 701 0.0188
734 RESPIRATORY TRACT CONGESTION 190 0.0188
735 OSTEONECROSIS OF JAW 364 0.0187
736 SKIN INFECTION 118 0.0187
737 HEART RATE INCREASED 1178 0.0187
738 HEPATIC CIRRHOSIS 214 0.0186
739 NASAL CONGESTION 615 0.0186
740 MYELODYSPLASTIC SYNDROME 187 0.0186
741 HYPOACUSIS 410 0.0186
742 ABDOMINAL PAIN LOWER 326 0.0186
743 UNEVALUABLE EVENT 958 0.0186
744 SKIN DISORDER 340 0.0186
745 TRANSFUSION 129 0.0185
746 DEPRESSED MOOD 605 0.0185
747 ROAD TRAFFIC ACCIDENT 513 0.0185
748 DEPRESSED LEVEL OF CONSCIOUSNESS 481 0.0184
749 EYELID PTOSIS 119 0.0184
750 HERPES ZOSTER 666 0.0184
751 BLINDNESS 455 0.0184
752 BLOOD LACTATE DEHYDROGENASE INCREASED 224 0.0184
753 HAEMORRHAGE 1215 0.0183
754 BLOOD THYROID STIMULATING HORMONE INCREASED 117 0.0183
755 IMMUNODEFICIENCY 124 0.0183
756 COLON CANCER 162 0.0183
757 ERYTHEMA MULTIFORME 118 0.0182
758 LARYNGITIS 122 0.0182
759 CYST 143 0.0182
760 SCAR 214 0.0182
761 SEPTIC SHOCK 480 0.0181
762 DRUG HYPERSENSITIVITY 2404 0.0181
763 AGGRESSION 680 0.0180
764 HIP ARTHROPLASTY 140 0.0180
765 SLUGGISHNESS 122 0.0180
766 MEDICATION ERROR 703 0.0180
767 AGITATION 975 0.0180
768 BONE PAIN 700 0.0179
769 LUNG INFECTION 285 0.0179
770 LABORATORY TEST ABNORMAL 325 0.0179
771 EYE DISORDER 358 0.0179
772 CONVULSION 1039 0.0178
773 FRACTURE 240 0.0178
774 HUNGER 123 0.0178
775 BREAST PAIN 139 0.0178
776 METASTASES TO LIVER 186 0.0177
777 ALOPECIA 2301 0.0177
778 SNEEZING 228 0.0177
779 VIRAL INFECTION 366 0.0176
780 TOOTH EXTRACTION 152 0.0176
781 EYE PAIN 539 0.0176
782 LUNG DISORDER 525 0.0175
783 WRONG TECHNIQUE IN DRUG USAGE PROCESS 641 0.0175
784 GASTROENTERITIS VIRAL 195 0.0175
785 STOMATITIS 622 0.0175
786 CONDITION AGGRAVATED 2655 0.0175
787 LYMPHOMA 162 0.0174
788 FUNGAL INFECTION 364 0.0174
789 METASTASES TO BONE 152 0.0174
790 CONJUNCTIVITIS 163 0.0174
791 THIRST 185 0.0173
792 LIVER DISORDER 481 0.0173
793 SWELLING 937 0.0173
794 HEPATIC FAILURE 372 0.0173
795 DISABILITY 159 0.0172
796 NEUROLEPTIC MALIGNANT SYNDROME 144 0.0172
797 ASCITES 336 0.0171
798 GASTRIC DISORDER 469 0.0171
799 BLOOD TEST ABNORMAL 124 0.0171
800 PHARYNGITIS 146 0.0171
801 MUSCULOSKELETAL DISORDER 220 0.0170
802 BACTERIAL INFECTION 185 0.0170
803 EYELID OEDEMA 164 0.0169
804 SKIN FISSURES 133 0.0169
805 THROAT TIGHTNESS 302 0.0169
806 ASTHMA 937 0.0169
807 PHOTOPHOBIA 189 0.0168
808 DRUG TOXICITY 235 0.0168
809 LEUKOPENIA 541 0.0168
810 CHOLESTASIS 202 0.0167
811 RESPIRATORY TRACT INFECTION 256 0.0166
812 SOPOR 160 0.0166
813 PANIC ATTACK 413 0.0165
814 MULTIPLE ORGAN DYSFUNCTION SYNDROME 203 0.0165
815 FREQUENT BOWEL MOVEMENTS 216 0.0164
816 WHITE BLOOD CELL COUNT DECREASED 1048 0.0164
817 OCULAR HYPERAEMIA 423 0.0163
818 ILL-DEFINED DISORDER 396 0.0163
819 PRESCRIBED OVERDOSE 200 0.0163
820 LYMPHADENOPATHY 360 0.0163
821 FACE OEDEMA 196 0.0162
822 TOOTH LOSS 169 0.0162
823 PNEUMOTHORAX 158 0.0162
824 HEADACHE 6596 0.0162
825 RASH 4102 0.0161
826 PYREXIA 3583 0.0161
827 DRUG INTOLERANCE 830 0.0161
828 INCREASED APPETITE 177 0.0160
829 CHOLECYSTECTOMY 121 0.0160
830 DISCOMFORT 465 0.0160
831 NO THERAPEUTIC RESPONSE 198 0.0160
832 THROAT IRRITATION 435 0.0159
833 EPILEPSY 290 0.0159
834 EYE IRRITATION 462 0.0158
835 INJECTION SITE EXTRAVASATION 149 0.0158
836 HALLUCINATION, AUDITORY 163 0.0156
837 THERAPEUTIC RESPONSE UNEXPECTED 474 0.0156
838 BRONCHOSPASM 160 0.0156
839 SEDATION 240 0.0155
840 PSYCHOTIC DISORDER 323 0.0155
841 HEPATOCELLULAR INJURY 163 0.0154
842 INFLUENZA 1025 0.0153
843 RASH PAPULAR 248 0.0153
844 CYANOSIS 170 0.0152
845 ABSCESS 149 0.0151
846 NEUTROPHIL COUNT DECREASED 317 0.0151
847 MOOD ALTERED 281 0.0151
848 THINKING ABNORMAL 209 0.0151
849 INJECTION SITE HAEMATOMA 200 0.0151
850 ERYTHEMA 2018 0.0150
851 EAR INFECTION 223 0.0150
852 INCORRECT DRUG ADMINISTRATION DURATION 423 0.0150
853 LYMPHOCYTE COUNT DECREASED 160 0.0149
854 ABNORMAL BEHAVIOUR 479 0.0149
855 LIBIDO DECREASED 132 0.0149
856 GRAND MAL CONVULSION 139 0.0148
857 NASOPHARYNGITIS 1642 0.0148
858 STEVENS-JOHNSON SYNDROME 247 0.0147
859 SKIN EXFOLIATION 713 0.0147
860 SUICIDAL IDEATION 939 0.0146
861 INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION 1043 0.0146
862 GASTROINTESTINAL DISORDER 640 0.0145
863 RESPIRATORY DISORDER 282 0.0144
864 DISSEMINATED INTRAVASCULAR COAGULATION 150 0.0144
865 IRRITABILITY 641 0.0144
866 INFECTION 1188 0.0143
867 PRODUCT QUALITY ISSUE 1565 0.0143
868 EYE PRURITUS 225 0.0143
869 PHARMACEUTICAL PRODUCT COMPLAINT 382 0.0142
870 ANOSMIA 134 0.0142
871 INCORRECT DOSE ADMINISTERED 1423 0.0142
872 EMOTIONAL DISORDER 317 0.0141
873 DRUG ADMINISTRATION ERROR 436 0.0141
874 ANGER 355 0.0141
875 PLASMA CELL MYELOMA 300 0.0141
876 ANAPHYLACTIC REACTION 446 0.0141
877 LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES 209 0.0140
878 MANIA 167 0.0139
879 DISEASE RECURRENCE 206 0.0139
880 DISEASE PROGRESSION 886 0.0139
881 PSORIASIS 1089 0.0139
882 WRONG DRUG ADMINISTERED 125 0.0139
883 INTENTIONAL PRODUCT MISUSE 749 0.0139
884 MUCOSAL INFLAMMATION 231 0.0139
885 HEPATIC FUNCTION ABNORMAL 306 0.0139
886 HYPERSENSITIVITY 1613 0.0138
887 COMA 448 0.0138
888 LIVER FUNCTION TEST INCREASED 139 0.0138
889 BLADDER CANCER 261 0.0137
890 NEUTROPENIA 973 0.0137
891 SKIN REACTION 125 0.0136
892 PULMONARY ARTERIAL HYPERTENSION 143 0.0136
893 SURGERY 411 0.0136
894 PSYCHOMOTOR HYPERACTIVITY 170 0.0135
895 INTENTIONAL PRODUCT USE ISSUE 458 0.0135
896 FEEDING DISORDER 120 0.0133
897 DRUG DISPENSING ERROR 205 0.0133
898 INFLUENZA LIKE ILLNESS 809 0.0132
899 ACCIDENTAL OVERDOSE 296 0.0130
900 DRUG DOSE OMISSION 2163 0.0130
901 INTENTIONAL DRUG MISUSE 280 0.0130
902 FEBRILE NEUTROPENIA 487 0.0130
903 URTICARIA 1332 0.0130
904 INTESTINAL OBSTRUCTION 286 0.0129
905 PSORIATIC ARTHROPATHY 224 0.0129
906 PRODUCT SUBSTITUTION ISSUE 500 0.0128
907 DEVICE RELATED INFECTION 144 0.0128
908 DEVICE MALFUNCTION 386 0.0128
909 RESPIRATORY ARREST 284 0.0126
910 DRUG ADMINISTERED AT INAPPROPRIATE SITE 133 0.0126
911 COLITIS ULCERATIVE 226 0.0125
912 ALTERED STATE OF CONSCIOUSNESS 161 0.0125
913 INJECTION SITE MASS 263 0.0125
914 PERITONITIS 192 0.0125
915 CRYING 346 0.0125
916 NEOPLASM MALIGNANT 405 0.0124
917 BREAST CANCER 443 0.0124
918 NERVOUS SYSTEM DISORDER 302 0.0124
919 WITHDRAWAL SYNDROME 309 0.0124
920 ORAL HERPES 135 0.0123
921 COMPLETED SUICIDE 769 0.0123
922 INJECTION SITE HAEMORRHAGE 560 0.0122
923 RENAL CANCER 129 0.0122
924 SEIZURE 717 0.0122
925 TOXICITY TO VARIOUS AGENTS 1194 0.0121
926 DRUG EFFECT DECREASED 658 0.0120
927 RHEUMATOID ARTHRITIS 773 0.0120
928 DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 322 0.0120
929 OVERDOSE 1317 0.0119
930 THERAPY CESSATION 360 0.0119
931 EXPIRED PRODUCT ADMINISTERED 246 0.0118
932 PROCEDURAL PAIN 196 0.0118
933 DRUG EFFECT INCOMPLETE 432 0.0118
934 ADVERSE DRUG REACTION 513 0.0117
935 DRUG INEFFECTIVE 9174 0.0116
936 PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME 163 0.0114
937 BONE DENSITY DECREASED 166 0.0113
938 ADVERSE EVENT 692 0.0112
939 CIRCUMSTANCE OR INFORMATION CAPABLE OF LEADING TO MEDICATION ERROR 150 0.0112
940 AGRANULOCYTOSIS 121 0.0111
941 SYSTEMIC LUPUS ERYTHEMATOSUS 164 0.0110
942 THERAPEUTIC RESPONSE DECREASED 406 0.0109
943 PRODUCT USE ISSUE 1110 0.0109
944 UNDERDOSE 506 0.0108
945 EXTRA DOSE ADMINISTERED 167 0.0108
946 OFF LABEL USE 3850 0.0108
947 APPLICATION SITE PRURITUS 175 0.0106
948 MALIGNANT NEOPLASM PROGRESSION 599 0.0106
949 SUICIDE ATTEMPT 430 0.0106
950 OSTEONECROSIS 237 0.0106
951 MOOD SWINGS 251 0.0106
952 PRODUCT DOSE OMISSION 736 0.0104
953 DRY SKIN 768 0.0104
954 INTENTIONAL OVERDOSE 378 0.0101
955 APPLICATION SITE ERYTHEMA 214 0.0100
956 MIGRAINE 550 0.0099
957 NEOPLASM PROGRESSION 182 0.0098
958 ANAPHYLACTIC SHOCK 153 0.0097
959 INJECTION SITE PAIN 1704 0.0097
960 INFUSION RELATED REACTION 300 0.0097
961 SKIN BURNING SENSATION 469 0.0095
962 BONE MARROW FAILURE 169 0.0095
963 INJECTION SITE PRURITUS 417 0.0094
964 BREAST CANCER FEMALE 147 0.0093
965 APPLICATION SITE PAIN 150 0.0093
966 DRUG WITHDRAWAL SYNDROME 412 0.0093
967 EXTRAPYRAMIDAL DISORDER 197 0.0092
968 PELVIC PAIN 118 0.0091
969 MULTIPLE SCLEROSIS RELAPSE 453 0.0091
970 INTENTIONAL SELF-INJURY 126 0.0090
971 PRODUCT ADHESION ISSUE 170 0.0087
972 PAIN OF SKIN 155 0.0086
973 TARDIVE DYSKINESIA 207 0.0086
974 MULTIPLE SCLEROSIS 264 0.0085
975 INJECTION SITE ERYTHEMA 724 0.0085
976 DEATH 4272 0.0084
977 INJECTION SITE BRUISING 409 0.0082
978 THERAPY NON-RESPONDER 146 0.0081
979 PRODUCT USE IN UNAPPROVED INDICATION 725 0.0076
980 INJECTION SITE SWELLING 346 0.0075
981 DEVICE ISSUE 285 0.0073
982 INJECTION SITE RASH 130 0.0072
983 GYNAECOMASTIA 199 0.0072
984 HOSPITALISATION 542 0.0071
985 WRONG TECHNIQUE IN PRODUCT USAGE PROCESS 663 0.0071
986 INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 300 0.0068
987 VAGINAL HAEMORRHAGE 223 0.0068
988 INJECTION SITE REACTION 307 0.0066
989 SKIN IRRITATION 199 0.0065
990 INCORRECT ROUTE OF DRUG ADMINISTRATION 227 0.0063
991 DRUG DEPENDENCE 216 0.0057
992 NO ADVERSE EVENT 419 0.0052
993 ACNE 224 0.0043
994 FOETAL EXPOSURE DURING PREGNANCY 166 0.0036
995 DRUG ABUSE 177 0.0036
996 TREATMENT FAILURE 131 0.0030